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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for PLAG1

Z-value: 0.97

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
PLAG1
ENSG00000181690.8 PLAG1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PLAG1hg38_v1_chr8_-_56211257_562113090.057.9e-01Click!

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_38433676 2.22 ENST00000359596.8
ENST00000355481.8
RYR1
ryanodine receptor 1
chr12_+_57611420 2.03 ENST00000286494.9
ARHGEF25
Rho guanine nucleotide exchange factor 25
chr5_-_59893718 1.93 ENST00000340635.11
PDE4D
phosphodiesterase 4D
chr19_-_49155384 1.86 ENST00000252825.9
HRC
histidine rich calcium binding protein
chr6_-_83709019 1.81 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
SNAP91
synaptosome associated protein 91
chr14_-_25049889 1.80 ENST00000419632.6
ENST00000396700.5
STXBP6
syntaxin binding protein 6
chr14_-_25050111 1.67 ENST00000323944.9
STXBP6
syntaxin binding protein 6
chr19_-_49155130 1.66 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr9_+_69325168 1.59 ENST00000303068.14
FAM189A2
family with sequence similarity 189 member A2
chr1_-_145964567 1.52 ENST00000606888.3
ANKRD34A
ankyrin repeat domain 34A
chr3_+_42654470 1.51 ENST00000680014.1
ZBTB47
zinc finger and BTB domain containing 47
chr1_+_163068775 1.49 ENST00000421743.6
RGS4
regulator of G protein signaling 4
chr4_-_8127650 1.46 ENST00000545242.6
ENST00000676532.1
ABLIM2
actin binding LIM protein family member 2
chr3_-_116445458 1.45 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr12_+_78864768 1.38 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr3_-_51968387 1.37 ENST00000490063.5
ENST00000468324.5
ENST00000497653.5
ENST00000484633.5
PCBP4
poly(rC) binding protein 4
chr3_+_135965718 1.33 ENST00000264977.8
ENST00000490467.5
PPP2R3A
protein phosphatase 2 regulatory subunit B''alpha
chr14_+_79279906 1.31 ENST00000428277.6
NRXN3
neurexin 3
chr6_-_166308385 1.29 ENST00000322583.5
PRR18
proline rich 18
chr3_-_73624840 1.27 ENST00000308537.4
ENST00000263666.9
PDZRN3
PDZ domain containing ring finger 3
chr6_-_96897853 1.26 ENST00000316149.8
NDUFAF4
NADH:ubiquinone oxidoreductase complex assembly factor 4
chr12_+_56152579 1.24 ENST00000551834.5
ENST00000552568.5
MYL6B
myosin light chain 6B
chr20_+_58891981 1.24 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS
GNAS complex locus
chr5_+_161848536 1.21 ENST00000519621.2
ENST00000636573.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr1_+_202462730 1.20 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr1_+_150257247 1.15 ENST00000647854.1
CA14
carbonic anhydrase 14
chr3_-_116444983 1.13 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr5_+_161848314 1.12 ENST00000437025.6
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr2_-_74391780 1.11 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin subunit 1
chr11_+_71565563 1.10 ENST00000398531.3
KRTAP5-10
keratin associated protein 5-10
chr17_+_4951080 1.09 ENST00000521811.5
ENST00000323997.10
ENST00000522249.5
ENST00000519584.5
ENST00000519602.6
ENO3
enolase 3
chr8_-_143976722 1.07 ENST00000436759.6
ENST00000527303.2
PLEC
plectin
chr19_-_35135011 1.04 ENST00000310123.8
LGI4
leucine rich repeat LGI family member 4
chr14_+_79279403 1.03 ENST00000281127.11
NRXN3
neurexin 3
chr14_+_79279681 1.00 ENST00000679122.1
NRXN3
neurexin 3
chr6_-_29628038 0.99 ENST00000355973.7
ENST00000377012.8
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
chrX_+_52184874 0.98 ENST00000599522.7
ENST00000471932.6
MAGED4
MAGE family member D4
chr10_-_59709842 0.98 ENST00000395348.8
SLC16A9
solute carrier family 16 member 9
chr15_-_44194407 0.98 ENST00000484674.5
FRMD5
FERM domain containing 5
chr3_-_51967410 0.95 ENST00000461554.6
ENST00000483411.5
ENST00000461544.2
ENST00000355852.6
PCBP4
poly(rC) binding protein 4
chr1_-_160070102 0.93 ENST00000638728.1
ENST00000637644.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr4_+_41990496 0.92 ENST00000264451.12
SLC30A9
solute carrier family 30 member 9
chr5_+_161848112 0.92 ENST00000393943.10
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr17_+_47694053 0.91 ENST00000578982.5
TBKBP1
TBK1 binding protein 1
chr14_+_79279339 0.90 ENST00000557594.5
NRXN3
neurexin 3
chr2_-_74391837 0.90 ENST00000417090.1
ENST00000409868.5
ENST00000680606.1
DCTN1
dynactin subunit 1
chr1_-_151165847 0.90 ENST00000368908.10
ENST00000440902.2
LYSMD1
LysM domain containing 1
chr17_+_50835578 0.87 ENST00000311378.5
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr2_+_169733811 0.87 ENST00000392647.7
KLHL23
kelch like family member 23
chr19_-_35135180 0.84 ENST00000392225.7
LGI4
leucine rich repeat LGI family member 4
chr14_+_79280056 0.84 ENST00000676811.1
NRXN3
neurexin 3
chr2_-_74392025 0.84 ENST00000440727.1
ENST00000409240.5
DCTN1
dynactin subunit 1
chr22_+_29073112 0.84 ENST00000327813.9
ENST00000407188.5
KREMEN1
kringle containing transmembrane protein 1
chr16_+_56451513 0.81 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
OGFOD1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr2_-_179861604 0.81 ENST00000410066.7
ZNF385B
zinc finger protein 385B
chr11_+_46277648 0.80 ENST00000621158.5
CREB3L1
cAMP responsive element binding protein 3 like 1
chrX_+_111096136 0.79 ENST00000372007.10
PAK3
p21 (RAC1) activated kinase 3
chr19_+_3359563 0.78 ENST00000589123.5
ENST00000395111.7
ENST00000586919.5
NFIC
nuclear factor I C
chr1_-_160070150 0.77 ENST00000644903.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr4_-_113761563 0.75 ENST00000394522.7
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr1_-_231528541 0.75 ENST00000658645.1
ENST00000667843.1
ENST00000666601.1
ENST00000654602.1
ENST00000662999.1
ENST00000662216.1
ENST00000653908.1
ENSG00000233461.6
ENSG00000287856.1
novel transcript
novel protein
chrX_-_143636094 0.74 ENST00000356928.2
SLITRK4
SLIT and NTRK like family member 4
chr17_-_4704040 0.73 ENST00000570571.5
ENST00000575101.1
ENST00000574876.5
ENST00000572293.7
PELP1
proline, glutamate and leucine rich protein 1
chr9_-_128128102 0.72 ENST00000617202.4
PTGES2
prostaglandin E synthase 2
chrX_+_52184904 0.69 ENST00000375626.7
ENST00000467526.1
MAGED4
MAGE family member D4
chr10_+_988425 0.69 ENST00000360803.9
GTPBP4
GTP binding protein 4
chr10_+_134465 0.66 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
ZMYND11
zinc finger MYND-type containing 11
chr2_+_156436423 0.66 ENST00000540309.5
GPD2
glycerol-3-phosphate dehydrogenase 2
chr10_+_24208774 0.66 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
KIAA1217
chr17_-_3696033 0.66 ENST00000551178.5
ENST00000552276.5
ENST00000547178.5
P2RX5
purinergic receptor P2X 5
chr7_-_10940123 0.65 ENST00000339600.6
NDUFA4
NDUFA4 mitochondrial complex associated
chr2_+_241188509 0.63 ENST00000674324.1
ENST00000274979.12
ANO7
anoctamin 7
chr10_+_24209129 0.62 ENST00000376454.8
ENST00000635504.1
KIAA1217
KIAA1217
chr16_-_29899532 0.61 ENST00000308713.9
ENST00000617533.5
SEZ6L2
seizure related 6 homolog like 2
chr3_-_197297523 0.61 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
DLG1
discs large MAGUK scaffold protein 1
chr19_-_49061997 0.59 ENST00000593537.1
NTF4
neurotrophin 4
chr4_-_113761724 0.58 ENST00000511664.6
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr13_+_53028806 0.58 ENST00000219022.3
OLFM4
olfactomedin 4
chr9_+_136980211 0.57 ENST00000444903.2
PTGDS
prostaglandin D2 synthase
chrX_-_138711663 0.56 ENST00000315930.11
FGF13
fibroblast growth factor 13
chr11_-_1585283 0.56 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chrX_+_70282093 0.55 ENST00000509895.5
ENST00000374473.6
ENST00000276066.4
RAB41
RAB41, member RAS oncogene family
chr7_-_158587710 0.55 ENST00000389416.8
PTPRN2
protein tyrosine phosphatase receptor type N2
chr6_-_35497042 0.55 ENST00000639578.3
ENST00000338863.13
TEAD3
TEA domain transcription factor 3
chrX_+_111096211 0.54 ENST00000372010.5
ENST00000519681.5
PAK3
p21 (RAC1) activated kinase 3
chr11_-_73598067 0.54 ENST00000450446.6
ENST00000356467.5
FAM168A
family with sequence similarity 168 member A
chr1_-_31704001 0.53 ENST00000373672.8
COL16A1
collagen type XVI alpha 1 chain
chr1_-_115338231 0.52 ENST00000369512.3
ENST00000680116.1
ENST00000681124.1
ENST00000675637.2
ENST00000676038.2
NGF
nerve growth factor
chr19_+_50205437 0.52 ENST00000642980.1
MYH14
myosin heavy chain 14
chr16_-_56451316 0.50 ENST00000300291.10
NUDT21
nudix hydrolase 21
chr14_-_74612226 0.50 ENST00000261978.9
LTBP2
latent transforming growth factor beta binding protein 2
chr2_-_109614143 0.49 ENST00000356688.8
SEPTIN10
septin 10
chr1_-_44017296 0.49 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
SLC6A9
solute carrier family 6 member 9
chr11_+_65576023 0.49 ENST00000533237.5
ENST00000309295.9
ENST00000634639.1
EHBP1L1
EH domain binding protein 1 like 1
chr20_+_38724478 0.48 ENST00000217420.2
SLC32A1
solute carrier family 32 member 1
chr1_-_93614091 0.48 ENST00000370247.7
BCAR3
BCAR3 adaptor protein, NSP family member
chr19_+_40467145 0.48 ENST00000338932.7
SPTBN4
spectrin beta, non-erythrocytic 4
chr17_-_1400168 0.48 ENST00000573026.1
ENST00000575977.1
ENST00000571732.5
ENST00000264335.13
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
chr1_+_26993684 0.47 ENST00000522111.3
TRNP1
TMF1 regulated nuclear protein 1
chr4_-_113761927 0.46 ENST00000296402.9
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr19_+_40466976 0.45 ENST00000598249.6
SPTBN4
spectrin beta, non-erythrocytic 4
chr11_+_118607579 0.45 ENST00000530708.4
PHLDB1
pleckstrin homology like domain family B member 1
chr10_+_134703 0.45 ENST00000509513.6
ZMYND11
zinc finger MYND-type containing 11
chr15_-_43618240 0.43 ENST00000432436.1
STRC
stereocilin
chr1_-_204685700 0.43 ENST00000367177.4
LRRN2
leucine rich repeat neuronal 2
chr17_+_66835110 0.41 ENST00000533854.6
CACNG5
calcium voltage-gated channel auxiliary subunit gamma 5
chr17_-_1684807 0.41 ENST00000577001.1
ENST00000572621.5
ENST00000304992.11
PRPF8
pre-mRNA processing factor 8
chr2_-_127642131 0.41 ENST00000426981.5
LIMS2
LIM zinc finger domain containing 2
chr4_-_113761441 0.40 ENST00000394524.7
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr19_-_38229654 0.40 ENST00000412732.5
ENST00000456296.5
DPF1
double PHD fingers 1
chr16_-_30096170 0.40 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
YPEL3
yippee like 3
chr16_+_31472130 0.40 ENST00000394863.8
ENST00000565360.5
ENST00000361773.7
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr14_-_31026363 0.40 ENST00000357479.10
ENST00000355683.9
STRN3
striatin 3
chrX_-_45200828 0.40 ENST00000398000.7
DIPK2B
divergent protein kinase domain 2B
chrX_+_150361559 0.39 ENST00000262858.8
MAMLD1
mastermind like domain containing 1
chr12_+_48815566 0.38 ENST00000536187.6
CACNB3
calcium voltage-gated channel auxiliary subunit beta 3
chr14_-_21526202 0.38 ENST00000450879.2
SALL2
spalt like transcription factor 2
chr11_+_1629775 0.38 ENST00000399676.3
KRTAP5-5
keratin associated protein 5-5
chr16_+_31117656 0.38 ENST00000219797.9
ENST00000448516.6
KAT8
lysine acetyltransferase 8
chr17_+_50274447 0.38 ENST00000507382.2
TMEM92
transmembrane protein 92
chr8_+_22054817 0.38 ENST00000432128.5
ENST00000443491.6
ENST00000517600.5
ENST00000523782.6
DMTN
dematin actin binding protein
chr19_-_55580829 0.37 ENST00000592239.1
ENST00000325421.7
ZNF579
zinc finger protein 579
chr16_-_29899043 0.37 ENST00000346932.9
ENST00000350527.7
ENST00000568380.1
SEZ6L2
seizure related 6 homolog like 2
chr2_-_109614087 0.37 ENST00000423520.5
SEPTIN10
septin 10
chr16_+_14833713 0.36 ENST00000287667.12
ENST00000620755.4
ENST00000610363.4
NOMO1
NODAL modulator 1
chr18_+_58864352 0.36 ENST00000590287.5
ZNF532
zinc finger protein 532
chr2_-_152099155 0.35 ENST00000637309.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr11_-_73598183 0.35 ENST00000064778.8
FAM168A
family with sequence similarity 168 member A
chr9_-_132944600 0.35 ENST00000490179.3
ENST00000643583.1
ENST00000298552.9
ENST00000643072.1
ENST00000642745.1
ENST00000647462.1
ENST00000643875.1
ENST00000642627.1
ENST00000475903.6
ENST00000642617.1
ENST00000642646.1
ENST00000646625.1
ENST00000645150.1
ENST00000645129.1
ENST00000403810.6
ENST00000643691.1
ENST00000644097.1
TSC1
TSC complex subunit 1
chr14_-_100903696 0.34 ENST00000649591.1
RTL1
retrotransposon Gag like 1
chr9_-_133129395 0.34 ENST00000393157.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr1_-_160070125 0.33 ENST00000639408.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr9_-_133336169 0.33 ENST00000372022.6
SURF6
surfeit 6
chr22_+_29205877 0.32 ENST00000334018.11
ENST00000429226.5
ENST00000404755.7
ENST00000404820.7
ENST00000430127.1
EMID1
EMI domain containing 1
chrX_-_16870153 0.32 ENST00000493145.1
RBBP7
RB binding protein 7, chromatin remodeling factor
chr17_-_28812392 0.31 ENST00000452648.8
FAM222B
family with sequence similarity 222 member B
chr3_-_197298000 0.31 ENST00000664991.1
DLG1
discs large MAGUK scaffold protein 1
chr3_+_49673939 0.31 ENST00000449966.5
APEH
acylaminoacyl-peptide hydrolase
chr3_+_69763726 0.30 ENST00000448226.9
MITF
melanocyte inducing transcription factor
chr3_-_197298092 0.30 ENST00000392382.6
DLG1
discs large MAGUK scaffold protein 1
chr5_+_10353668 0.30 ENST00000274140.10
ENST00000449913.6
ENST00000503788.5
MARCHF6
membrane associated ring-CH-type finger 6
chr16_-_29899245 0.29 ENST00000537485.5
SEZ6L2
seizure related 6 homolog like 2
chr14_-_21526312 0.29 ENST00000537235.2
SALL2
spalt like transcription factor 2
chr1_+_2476315 0.27 ENST00000419816.6
PLCH2
phospholipase C eta 2
chr19_-_38229714 0.26 ENST00000416611.5
DPF1
double PHD fingers 1
chr12_-_57738740 0.26 ENST00000547588.6
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_26500296 0.26 ENST00000684113.1
BTN1A1
butyrophilin subfamily 1 member A1
chr13_+_99981775 0.25 ENST00000376335.8
ZIC2
Zic family member 2
chr19_-_49878350 0.25 ENST00000391834.6
ENST00000391830.1
AKT1S1
AKT1 substrate 1
chr1_-_31704319 0.25 ENST00000373668.7
COL16A1
collagen type XVI alpha 1 chain
chr16_+_285680 0.24 ENST00000435833.1
PDIA2
protein disulfide isomerase family A member 2
chr17_-_28812224 0.24 ENST00000582059.6
FAM222B
family with sequence similarity 222 member B
chr12_-_112382363 0.24 ENST00000682272.1
ENST00000377560.9
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chrX_-_16869840 0.23 ENST00000380084.8
RBBP7
RB binding protein 7, chromatin remodeling factor
chr3_+_184135343 0.23 ENST00000648915.2
ENST00000432569.2
ENST00000647909.1
EIF2B5
eukaryotic translation initiation factor 2B subunit epsilon
chr8_+_22056837 0.23 ENST00000520174.5
DMTN
dematin actin binding protein
chr1_+_151166001 0.22 ENST00000368902.1
ENST00000368905.9
SCNM1
sodium channel modifier 1
chr5_+_110738983 0.21 ENST00000355943.8
ENST00000447245.6
SLC25A46
solute carrier family 25 member 46
chr11_+_71527267 0.21 ENST00000398536.6
KRTAP5-7
keratin associated protein 5-7
chr9_+_136327526 0.20 ENST00000440944.6
GPSM1
G protein signaling modulator 1
chr7_-_73328082 0.20 ENST00000333149.7
TRIM50
tripartite motif containing 50
chr5_+_171420016 0.20 ENST00000675071.1
ENSG00000288639.1
novel protein
chr7_-_72969466 0.20 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr4_+_61200318 0.19 ENST00000683033.1
ADGRL3
adhesion G protein-coupled receptor L3
chr17_-_76141240 0.19 ENST00000322957.7
FOXJ1
forkhead box J1
chr10_-_31928790 0.18 ENST00000375250.9
ENST00000344936.7
ARHGAP12
Rho GTPase activating protein 12
chr19_-_461007 0.18 ENST00000264554.11
SHC2
SHC adaptor protein 2
chr1_+_6447331 0.17 ENST00000632803.1
ENST00000632593.1
ESPN
espin
chr19_-_9214871 0.17 ENST00000308682.3
OR7D4
olfactory receptor family 7 subfamily D member 4
chr14_-_57866075 0.16 ENST00000556826.6
SLC35F4
solute carrier family 35 member F4
chr1_+_2476284 0.16 ENST00000378486.8
PLCH2
phospholipase C eta 2
chr16_-_46689145 0.15 ENST00000299138.12
VPS35
VPS35 retromer complex component
chr19_-_13906062 0.14 ENST00000591586.5
ENST00000346736.6
BRME1
break repair meiotic recombinase recruitment factor 1
chr11_-_71582837 0.14 ENST00000617152.1
ENST00000398530.1
KRTAP5-11
keratin associated protein 5-11
chr17_+_20579724 0.14 ENST00000661883.1
ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15 like 2
chr11_+_57338344 0.14 ENST00000263314.3
ENST00000616487.4
P2RX3
purinergic receptor P2X 3
chr6_-_36986122 0.13 ENST00000460219.2
ENST00000373627.10
ENST00000373616.9
MTCH1
mitochondrial carrier 1
chr6_-_31972290 0.12 ENST00000375349.7
DXO
decapping exoribonuclease
chr7_-_6531186 0.12 ENST00000435185.5
GRID2IP
Grid2 interacting protein
chr1_-_151327650 0.12 ENST00000368875.6
ENST00000529142.5
PI4KB
phosphatidylinositol 4-kinase beta
chr15_+_22094522 0.12 ENST00000328795.5
OR4N4
olfactory receptor family 4 subfamily N member 4
chr1_-_151327365 0.12 ENST00000438243.2
ENST00000489223.2
ENST00000368873.6
ENST00000430800.5
ENST00000368872.5
PI4KB
phosphatidylinositol 4-kinase beta
chr7_+_75395629 0.11 ENST00000323819.7
ENST00000430211.5
TRIM73
tripartite motif containing 73
chr13_-_99971739 0.11 ENST00000267294.4
ZIC5
Zic family member 5
chr11_-_95231046 0.10 ENST00000416495.6
ENST00000536441.7
SESN3
sestrin 3
chr19_+_13906190 0.10 ENST00000318003.11
CC2D1A
coiled-coil and C2 domain containing 1A
chr10_-_70283998 0.09 ENST00000277942.7
NPFFR1
neuropeptide FF receptor 1
chr10_-_73414027 0.09 ENST00000372921.10
ENST00000372919.8
ANXA7
annexin A7
chr11_+_65919383 0.09 ENST00000312515.7
DRAP1
DR1 associated protein 1
chr6_-_70303070 0.09 ENST00000370496.3
ENST00000357250.11
COL9A1
collagen type IX alpha 1 chain
chrX_-_47145035 0.09 ENST00000276062.8
NDUFB11
NADH:ubiquinone oxidoreductase subunit B11
chr9_+_128689948 0.08 ENST00000372688.8
ENST00000372686.5
SET
SET nuclear proto-oncogene
chr6_+_31715339 0.08 ENST00000375824.1
ENST00000375825.7
LY6G6D
lymphocyte antigen 6 family member G6D
chr14_-_54488658 0.08 ENST00000553333.1
GMFB
glia maturation factor beta
chrX_+_21940978 0.07 ENST00000457085.1
SMS
spermine synthase
chr1_-_151327684 0.07 ENST00000368874.8
PI4KB
phosphatidylinositol 4-kinase beta
chr2_-_29921580 0.07 ENST00000389048.8
ALK
ALK receptor tyrosine kinase
chr16_-_18801424 0.07 ENST00000546206.6
ENST00000562819.5
ENST00000304414.12
ENST00000562234.2
ENST00000567078.2
ARL6IP1
ENSG00000260342.2
ADP ribosylation factor like GTPase 6 interacting protein 1
novel protein
chr2_-_55419276 0.06 ENST00000646796.1
CCDC88A
coiled-coil domain containing 88A
chr12_-_12266769 0.06 ENST00000543091.1
LRP6
LDL receptor related protein 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.3 2.8 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.3 0.9 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 2.0 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.7 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 3.5 GO:0051601 exocyst localization(GO:0051601)
0.2 0.6 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.2 1.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.5 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 0.2 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823)
0.1 2.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 2.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 5.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.3 GO:0006407 rRNA export from nucleus(GO:0006407)
0.1 3.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.6 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 2.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 1.2 GO:1903760 regulation of potassium ion export(GO:1902302) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.9 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.8 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 1.0 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.6 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.9 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409) glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.8 GO:0033622 integrin activation(GO:0033622)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.9 GO:0006829 zinc II ion transport(GO:0006829)
0.0 2.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 1.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 1.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.7 GO:0010524 positive regulation of calcium ion transport into cytosol(GO:0010524)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 3.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 2.8 GO:0005869 dynactin complex(GO:0005869)
0.2 1.4 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 3.5 GO:0000145 exocyst(GO:0000145)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 3.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.9 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 4.7 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 1.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 8.0 GO:0098793 presynapse(GO:0098793)
0.0 1.2 GO:0031672 A band(GO:0031672)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.4 3.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 2.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 5.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 1.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.8 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.7 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.1 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 3.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 3.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.1 2.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.0 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 3.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 3.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression