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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for TFCP2L1

Z-value: 0.33

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Transcription factors associated with TFCP2L1

Gene Symbol Gene ID Gene Info
ENSG00000115112.8 TFCP2L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2L1hg38_v1_chr2_-_121285194_1212852090.183.3e-01Click!

Activity profile of TFCP2L1 motif

Sorted Z-values of TFCP2L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2L1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_46413548 4.05 ENST00000307522.5
coiled-coil domain containing 8
chr12_+_40692413 3.56 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr1_-_153565535 2.93 ENST00000368707.5
S100 calcium binding protein A2
chr16_-_65121930 2.87 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
cadherin 11
chr11_-_119423162 2.84 ENST00000284240.10
ENST00000524970.5
Thy-1 cell surface antigen
chr15_-_51094897 2.75 ENST00000637513.2
TNF alpha induced protein 8 like 3
chr1_-_225941383 2.71 ENST00000420304.6
left-right determination factor 2
chr1_-_225941212 2.64 ENST00000366820.10
left-right determination factor 2
chr1_-_204359885 2.59 ENST00000414478.1
ENST00000272203.8
pleckstrin homology domain containing A6
chr15_+_74174403 2.51 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine rich repeat
chr2_-_55923775 2.25 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr5_+_141475928 2.23 ENST00000611950.1
ENST00000308177.5
ENST00000617641.4
ENST00000621008.1
ENST00000617222.4
protocadherin gamma subfamily C, 3
chr9_-_124507382 2.23 ENST00000373588.9
ENST00000620110.4
nuclear receptor subfamily 5 group A member 1
chr6_-_31730198 2.13 ENST00000375787.6
dimethylarginine dimethylaminohydrolase 2
chr14_+_58637934 2.04 ENST00000395153.8
dishevelled binding antagonist of beta catenin 1
chr9_-_127122623 2.03 ENST00000373417.1
ENST00000373425.8
angiopoietin like 2
chr11_-_119423193 2.02 ENST00000580275.5
Thy-1 cell surface antigen
chr1_+_26863140 2.02 ENST00000339276.6
stratifin
chr17_+_42851167 2.00 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr17_+_7888783 1.92 ENST00000330494.12
ENST00000358181.8
chromodomain helicase DNA binding protein 3
chr1_+_204870831 1.89 ENST00000404076.5
ENST00000539706.6
neurofascin
chr1_-_1421302 1.87 ENST00000520296.5
ankyrin repeat domain 65
chr1_-_155990062 1.80 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr20_+_56629296 1.80 ENST00000201031.3
transcription factor AP-2 gamma
chr19_-_12140315 1.79 ENST00000418866.1
ENST00000600335.5
ENST00000334213.10
zinc finger protein 20
chr1_-_1421248 1.78 ENST00000442470.1
ENST00000537107.6
ankyrin repeat domain 65
chr10_-_98011320 1.75 ENST00000309155.3
cartilage acidic protein 1
chr1_-_45623967 1.74 ENST00000445048.2
ENST00000421127.6
ENST00000528266.6
coiled-coil domain containing 17
chr20_+_36154630 1.71 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
erythrocyte membrane protein band 4.1 like 1
chr14_-_68937942 1.68 ENST00000684182.1
actinin alpha 1
chr19_+_47713412 1.67 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr17_-_28711660 1.64 ENST00000439862.7
ENST00000581289.1
ENST00000301039.6
ENST00000682792.1
protein interacting with cyclin A1
chr3_-_123692347 1.63 ENST00000508240.1
myosin light chain kinase
chr16_+_84294853 1.58 ENST00000219454.10
WAP four-disulfide core domain 1
chr16_+_84294823 1.56 ENST00000568638.1
WAP four-disulfide core domain 1
chr6_-_31729260 1.56 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr14_-_106803221 1.55 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr1_-_111200633 1.51 ENST00000357640.9
DENN domain containing 2D
chr3_+_71753834 1.51 ENST00000304411.3
G protein-coupled receptor 27
chr5_+_122311740 1.47 ENST00000506272.5
ENST00000508681.5
ENST00000509154.6
synuclein alpha interacting protein
chr5_+_52989314 1.47 ENST00000296585.10
integrin subunit alpha 2
chr14_+_96204679 1.46 ENST00000542454.2
ENST00000539359.1
ENST00000554311.2
ENST00000553811.1
bradykinin receptor B2
novel protein
chr21_-_30216047 1.45 ENST00000399899.2
claudin 8
chr1_+_27342014 1.45 ENST00000618673.4
ENST00000318074.9
ENST00000616558.5
synaptotagmin like 1
chr1_-_182604379 1.45 ENST00000367558.6
regulator of G protein signaling 16
chr5_+_177086867 1.44 ENST00000503708.5
ENST00000393648.6
ENST00000514472.1
ENST00000502906.5
ENST00000292408.9
ENST00000510911.5
fibroblast growth factor receptor 4
chr12_+_53097656 1.41 ENST00000301464.4
insulin like growth factor binding protein 6
chr8_-_6877928 1.41 ENST00000297439.4
defensin beta 1
chr19_-_20661563 1.38 ENST00000601440.6
ENST00000291750.6
ENST00000595094.1
zinc finger protein 626
novel transcript
chr4_+_84583037 1.35 ENST00000295887.6
CDP-diacylglycerol synthase 1
chr14_-_106154113 1.35 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr1_-_58784035 1.32 ENST00000371222.4
Jun proto-oncogene, AP-1 transcription factor subunit
chr4_-_25863537 1.32 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr10_-_119536533 1.31 ENST00000392865.5
regulator of G protein signaling 10
chr1_-_207032749 1.29 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr7_+_30921430 1.28 ENST00000409899.5
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr11_+_62613236 1.28 ENST00000278833.4
retinal outer segment membrane protein 1
chr11_-_62612725 1.27 ENST00000419857.1
ENST00000394773.7
EMAP like 3
chr5_-_180591488 1.26 ENST00000292641.4
secretoglobin family 3A member 1
chr12_+_93574965 1.25 ENST00000551883.1
ENST00000549510.1
suppressor of cytokine signaling 2
chr15_+_73926443 1.24 ENST00000261921.8
lysyl oxidase like 1
chr7_+_64313943 1.23 ENST00000423484.3
zinc finger protein 736
chr6_-_32763522 1.20 ENST00000435145.6
ENST00000437316.7
major histocompatibility complex, class II, DQ beta 2
chr8_-_53842899 1.20 ENST00000524234.1
ENST00000521275.5
ENST00000396774.6
ATPase H+ transporting V1 subunit H
chr2_+_90234809 1.19 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr1_+_151540299 1.19 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
tuftelin 1
chr8_-_27992663 1.19 ENST00000380385.6
ENST00000354914.8
scavenger receptor class A member 5
chrX_+_134237047 1.18 ENST00000370809.4
ENST00000517294.5
coiled-coil domain containing 160
chr6_-_31582415 1.15 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr2_-_168247569 1.15 ENST00000355999.5
serine/threonine kinase 39
chr2_-_72147819 1.12 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr19_-_20565769 1.12 ENST00000427401.9
zinc finger protein 737
chr17_+_7654096 1.12 ENST00000577113.1
ATPase Na+/K+ transporting subunit beta 2
chr20_+_9514562 1.12 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr12_+_55931148 1.10 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr7_-_128405930 1.10 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
inosine monophosphate dehydrogenase 1
chr13_-_36131286 1.09 ENST00000255448.8
ENST00000379892.4
doublecortin like kinase 1
chr1_-_161038907 1.09 ENST00000318289.14
ENST00000368023.7
ENST00000423014.3
ENST00000368024.5
thiosulfate sulfurtransferase like domain containing 1
chr14_+_58638023 1.08 ENST00000335867.4
dishevelled binding antagonist of beta catenin 1
chr19_-_20661507 1.05 ENST00000612591.4
ENST00000595405.1
zinc finger protein 626
chrX_+_70455093 1.04 ENST00000542398.1
discs large MAGUK scaffold protein 3
chr2_+_158968608 1.03 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr8_-_97277890 1.03 ENST00000322128.5
TSPY like 5
chr11_-_128867364 1.02 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr17_-_19716604 1.02 ENST00000325411.9
ENST00000350657.9
solute carrier family 47 member 2
chr12_+_48814451 1.01 ENST00000540990.5
calcium voltage-gated channel auxiliary subunit beta 3
chr12_+_52079700 1.00 ENST00000546390.2
small integral membrane protein 41
chr17_-_15263162 0.99 ENST00000674673.1
ENST00000675950.1
peripheral myelin protein 22
chr11_-_128867268 0.99 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr7_-_100158679 0.97 ENST00000456769.5
ENST00000316937.8
trafficking protein particle complex 14
chr4_-_163332589 0.96 ENST00000296533.3
ENST00000509586.5
ENST00000504391.5
ENST00000512819.1
neuropeptide Y receptor Y1
chr17_-_35448742 0.95 ENST00000534689.5
ENST00000532210.5
ENST00000285013.11
ENST00000526861.5
ENST00000531588.1
schlafen family member 13
chr10_+_100347225 0.95 ENST00000370355.3
stearoyl-CoA desaturase
chr2_-_31138429 0.93 ENST00000349752.10
polypeptide N-acetylgalactosaminyltransferase 14
chr19_-_11738882 0.92 ENST00000586121.1
ENST00000431998.1
ENST00000341191.11
ENST00000440527.1
zinc finger protein 823
chr17_+_77376083 0.92 ENST00000427674.6
septin 9
chr12_-_120369156 0.92 ENST00000257552.7
musashi RNA binding protein 1
chr19_-_12294819 0.90 ENST00000355684.6
ENST00000356109.10
zinc finger protein 44
chr7_+_129188622 0.90 ENST00000249373.8
smoothened, frizzled class receptor
chr19_-_19821704 0.89 ENST00000443905.6
ENST00000590766.5
ENST00000587452.5
ENST00000545006.1
ENST00000590319.1
ENST00000587461.5
ENST00000450683.6
ENST00000540806.7
ENST00000590274.1
zinc finger protein 506
novel transcript
chr6_-_32666648 0.89 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr11_-_65557740 0.89 ENST00000526927.5
latent transforming growth factor beta binding protein 3
chr13_-_36131352 0.88 ENST00000360631.8
doublecortin like kinase 1
chr16_-_2340703 0.87 ENST00000301732.10
ENST00000382381.7
ATP binding cassette subfamily A member 3
chr4_-_173334385 0.87 ENST00000446922.6
high mobility group box 2
chr7_+_66205325 0.87 ENST00000304842.6
ENST00000649664.1
tyrosylprotein sulfotransferase 1
chr11_+_95089804 0.87 ENST00000278505.5
endonuclease domain containing 1
chr1_-_43285559 0.86 ENST00000523677.6
chromosome 1 open reading frame 210
chr14_-_68979251 0.85 ENST00000438964.6
ENST00000679147.1
actinin alpha 1
chr17_+_64506953 0.84 ENST00000580188.1
ENST00000556440.7
ENST00000581056.5
centrosomal protein 95
chr1_+_205256189 0.84 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr7_+_64903247 0.83 ENST00000476120.1
zinc finger protein 273
chr3_-_64445396 0.82 ENST00000295902.11
prickle planar cell polarity protein 2
chr12_+_119178920 0.82 ENST00000281938.7
heat shock protein family B (small) member 8
chr2_-_20012661 0.81 ENST00000421259.2
ENST00000407540.8
matrilin 3
chr12_-_53232182 0.81 ENST00000425354.7
ENST00000546717.1
ENST00000394426.5
retinoic acid receptor gamma
chr1_+_54641754 0.80 ENST00000339553.9
ENST00000421030.7
maestro heat like repeat family member 7
chr12_+_41188301 0.80 ENST00000402685.7
PDZ domain containing ring finger 4
chr6_-_52995170 0.79 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr16_+_31355165 0.79 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr2_-_136118142 0.79 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr17_+_64507029 0.79 ENST00000553412.5
centrosomal protein 95
chr7_-_65006678 0.79 ENST00000394323.3
endogenous retrovirus group 3 member 1, envelope
chr20_+_346769 0.78 ENST00000609179.5
neurensin 2
chr1_+_116111395 0.78 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr15_+_100877714 0.78 ENST00000561338.5
aldehyde dehydrogenase 1 family member A3
chr20_-_54173976 0.77 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr14_-_106622837 0.77 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr8_+_54457927 0.77 ENST00000297316.5
SRY-box transcription factor 17
chr14_-_68979076 0.75 ENST00000538545.6
ENST00000684639.1
actinin alpha 1
chr12_+_119178953 0.75 ENST00000674542.1
heat shock protein family B (small) member 8
chr4_-_82430192 0.74 ENST00000621267.4
ENST00000614627.4
heterogeneous nuclear ribonucleoprotein D like
chr19_-_20565746 0.73 ENST00000594419.1
zinc finger protein 737
chr7_-_128031422 0.73 ENST00000249363.4
leucine rich repeat containing 4
chr19_-_1822038 0.73 ENST00000643515.1
RNA exonuclease 1 homolog
chr7_+_6615576 0.72 ENST00000457543.4
zinc finger protein 853
chr17_-_76027296 0.72 ENST00000301607.8
envoplakin
chr10_-_126388455 0.72 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chr18_-_48409292 0.71 ENST00000589194.5
ENST00000591279.5
ENST00000590855.5
ENST00000587107.5
ENST00000588970.5
ENST00000586525.5
ENST00000592387.5
ENST00000590800.6
zinc finger and BTB domain containing 7C
chrX_+_151397163 0.71 ENST00000330374.7
vacuolar ATPase assembly factor VMA21
chr14_-_106130061 0.71 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr20_-_33686371 0.71 ENST00000343380.6
E2F transcription factor 1
chr8_+_73008850 0.70 ENST00000679115.1
ENST00000517390.2
ENST00000678860.1
ENST00000678518.1
ENST00000276602.10
ENST00000276603.10
ENST00000518874.6
telomeric repeat binding factor 1
chr14_-_68979314 0.70 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
actinin alpha 1
chr2_+_240605417 0.70 ENST00000319838.10
ENST00000403859.1
G protein-coupled receptor 35
chr7_-_1028311 0.70 ENST00000412051.5
chromosome 7 open reading frame 50
chr17_+_16415553 0.70 ENST00000338560.12
transient receptor potential cation channel subfamily V member 2
chr3_-_50340804 0.69 ENST00000359365.9
ENST00000357043.6
Ras association domain family member 1
chr2_+_188291911 0.69 ENST00000410051.5
GULP PTB domain containing engulfment adaptor 1
chr12_+_57772587 0.69 ENST00000300209.13
EEF1A lysine methyltransferase 3
chr17_-_19716573 0.69 ENST00000433844.4
solute carrier family 47 member 2
chr19_-_12052954 0.68 ENST00000547628.2
zinc finger protein 878
chr9_+_113349514 0.68 ENST00000374183.5
B-box and SPRY domain containing
chr2_+_9206762 0.68 ENST00000315273.4
ENST00000281419.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr22_+_31093358 0.67 ENST00000404574.5
smoothelin
chr19_+_12064720 0.67 ENST00000550826.1
ENST00000439326.8
zinc finger protein 844
chr12_-_120904337 0.65 ENST00000353487.7
signal peptide peptidase like 3
chr17_+_42844573 0.64 ENST00000253799.8
ENST00000452774.2
amine oxidase copper containing 2
chr11_+_78188797 0.64 ENST00000530267.5
ubiquitin specific peptidase 35
chr7_+_64045420 0.64 ENST00000647787.1
ENST00000456806.3
novel transcript
zinc finger protein 727
chr22_+_20131781 0.64 ENST00000334554.12
ENST00000320602.11
ENST00000405930.3
zinc finger DHHC-type palmitoyltransferase 8
chr2_+_231781669 0.63 ENST00000410024.5
ENST00000611614.4
ENST00000409295.5
ENST00000409091.5
COP9 signalosome subunit 7B
chr14_-_68979274 0.62 ENST00000394419.9
actinin alpha 1
chr5_+_72179622 0.62 ENST00000504492.1
microtubule associated protein 1B
chr19_-_12484773 0.61 ENST00000397732.8
zinc finger protein 709
chr22_+_22734577 0.61 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr1_+_54641806 0.61 ENST00000409996.5
maestro heat like repeat family member 7
chrX_-_129523436 0.61 ENST00000371123.5
ENST00000371121.5
ENST00000371122.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr6_-_32763466 0.61 ENST00000427449.1
ENST00000411527.5
major histocompatibility complex, class II, DQ beta 2
chr10_+_79068955 0.60 ENST00000334512.10
zinc finger MIZ-type containing 1
chr3_-_50567646 0.60 ENST00000426034.5
ENST00000441239.5
chromosome 3 open reading frame 18
chr16_+_31355215 0.60 ENST00000562522.2
integrin subunit alpha X
chr1_-_161550591 0.60 ENST00000367967.7
ENST00000436743.6
ENST00000442336.1
Fc fragment of IgG receptor IIIa
chr2_+_71068636 0.58 ENST00000244204.11
ENST00000533981.5
N-acetylglucosamine kinase
chr12_-_121274510 0.58 ENST00000392474.6
calcium/calmodulin dependent protein kinase kinase 2
chr22_-_22508702 0.57 ENST00000626650.3
zinc finger protein 280B
chr12_+_57772648 0.57 ENST00000333012.5
EEF1A lysine methyltransferase 3
chr11_+_78188871 0.57 ENST00000528910.5
ENST00000529308.6
ubiquitin specific peptidase 35
chr4_-_173334249 0.55 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr5_-_149379286 0.54 ENST00000261796.4
interleukin 17B
chr1_-_155978524 0.54 ENST00000361247.9
Rho/Rac guanine nucleotide exchange factor 2
chr19_+_41219235 0.53 ENST00000359092.7
AXL receptor tyrosine kinase
chr5_-_140043069 0.53 ENST00000289409.8
ENST00000358522.7
ENST00000289422.11
ENST00000541337.5
ENST00000361474.6
neuregulin 2
chr3_-_50340933 0.53 ENST00000616212.4
Ras association domain family member 1
chr7_+_32957385 0.52 ENST00000538336.5
ENST00000242209.9
FKBP prolyl isomerase 9
chr19_+_11965029 0.52 ENST00000592625.5
ENST00000358987.8
ENST00000586494.1
ENST00000343949.9
zinc finger protein 763
chr19_+_11766989 0.51 ENST00000357901.5
zinc finger protein 441
chr11_+_96389985 0.51 ENST00000332349.5
JRK like
chr2_-_19990058 0.51 ENST00000281405.9
ENST00000345530.8
WD repeat domain 35
chr16_+_67528799 0.51 ENST00000379312.7
ENST00000042381.9
ENST00000540839.7
RHO family interacting cell polarization regulator 1
chr4_-_121823843 0.50 ENST00000274026.10
cyclin A2
chr1_+_26545833 0.49 ENST00000531382.5
ribosomal protein S6 kinase A1
chr10_+_100745570 0.49 ENST00000427256.6
ENST00000355243.8
paired box 2
chr4_-_82430399 0.48 ENST00000630827.1
ENST00000295470.10
heterogeneous nuclear ribonucleoprotein D like
chr19_+_20077967 0.48 ENST00000418063.3
zinc finger protein 90
chr1_+_1425854 0.48 ENST00000378821.4
transmembrane protein 88B
chr2_+_71068603 0.48 ENST00000443938.6
N-acetylglucosamine kinase
chr3_+_158110363 0.48 ENST00000683137.1
arginine and serine rich coiled-coil 1
chr17_+_44187210 0.48 ENST00000589785.1
ENST00000592825.1
ENST00000589184.5
transmembrane and ubiquitin like domain containing 2
chr15_+_43594027 0.48 ENST00000453733.5
ENST00000441322.6
ENST00000627381.1
creatine kinase, mitochondrial 1B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.0 3.1 GO:1904864 regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864)
0.5 1.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.5 2.4 GO:0007538 primary sex determination(GO:0007538)
0.4 1.3 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.4 1.1 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.3 2.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 1.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.3 2.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.2 GO:0018277 protein deamination(GO:0018277)
0.3 1.5 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 2.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 1.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 1.1 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.3 1.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 3.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.3 0.8 GO:0060796 inner cell mass cellular morphogenesis(GO:0001828) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) cardiac cell fate determination(GO:0060913)
0.2 1.7 GO:0046618 drug export(GO:0046618)
0.2 0.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 1.6 GO:0070384 Harderian gland development(GO:0070384)
0.2 0.9 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.4 GO:1903412 response to bile acid(GO:1903412)
0.2 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.9 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228) pancreas morphogenesis(GO:0061113)
0.2 0.9 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 1.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 0.5 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 3.7 GO:0000052 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.2 5.0 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.2 0.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.6 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.4 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.1 0.7 GO:0032214 regulation of telomere maintenance via semi-conservative replication(GO:0032213) negative regulation of telomere maintenance via semi-conservative replication(GO:0032214)
0.1 0.9 GO:2000669 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 1.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 1.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 2.9 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 1.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.8 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.8 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0060529 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.3 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 1.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:1904828 regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.0 0.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 1.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:0043366 beta selection(GO:0043366)
0.0 2.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 1.2 GO:0007035 vacuolar acidification(GO:0007035)
0.0 2.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 3.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 2.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 1.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 4.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.0 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of membrane repolarization during action potential(GO:0098903)
0.0 1.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.0 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 3.3 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 0.8 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 1.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 3.6 GO:0021549 cerebellum development(GO:0021549)
0.0 0.6 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.8 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 3.0 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.5 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 3.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 1.9 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 1.0 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 2.0 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 1.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 1.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.9 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 2.9 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.7 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 1.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.0 GO:1990393 3M complex(GO:1990393)
0.4 1.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.4 1.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.4 GO:1990742 microvesicle(GO:1990742)
0.2 1.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 0.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 1.8 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 0.8 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.2 0.9 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 4.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.3 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.1 4.5 GO:0005916 fascia adherens(GO:0005916)
0.1 2.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 3.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.4 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 7.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 1.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.5 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.9 GO:0033643 host cell part(GO:0033643)
0.0 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 2.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.4 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0097542 ciliary tip(GO:0097542)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5 2.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.5 3.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.5 2.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 4.9 GO:0034235 GPI anchor binding(GO:0034235)
0.4 1.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.4 1.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.4 1.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.4 1.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 1.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.3 1.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 1.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.2 3.1 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 1.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 2.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 2.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 2.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.4 GO:0002135 CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098)
0.1 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 1.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 1.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 5.0 GO:0017166 vinculin binding(GO:0017166)
0.1 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 1.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 1.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.2 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.9 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 3.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 3.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0019864 IgG binding(GO:0019864)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.2 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.3 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 6.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 6.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 4.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 3.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 3.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 4.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 5.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 5.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 2.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 7.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors