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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for ZBTB16

Z-value: 1.07

Motif logo

Transcription factors associated with ZBTB16

Gene Symbol Gene ID Gene Info
ENSG00000109906.15 ZBTB16

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB16hg38_v1_chr11_+_114059702_114059749-0.459.0e-03Click!

Activity profile of ZBTB16 motif

Sorted Z-values of ZBTB16 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB16

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_210303608 1.98 ENST00000341685.8
myosin light chain 1
chr15_-_53759634 1.77 ENST00000557913.5
ENST00000360509.10
WD repeat domain 72
chr4_-_48080172 1.74 ENST00000507351.1
TXK tyrosine kinase
chr11_-_13496018 1.73 ENST00000529816.1
parathyroid hormone
chr7_+_76461676 1.70 ENST00000425780.5
ENST00000456590.5
ENST00000451769.5
ENST00000324432.9
ENST00000457529.5
ENST00000446600.5
ENST00000430490.7
ENST00000413936.6
ENST00000423646.5
ENST00000438930.5
deltex E3 ubiquitin ligase 2
chr15_-_53733103 1.60 ENST00000559418.5
WD repeat domain 72
chr14_-_45253161 1.51 ENST00000451174.1
ENST00000310806.9
MIS18 binding protein 1
chr12_-_53207241 1.48 ENST00000267082.10
ENST00000549086.2
integrin subunit beta 7
chr8_+_66126896 1.47 ENST00000353317.9
tripartite motif containing 55
chr1_+_110451132 1.45 ENST00000271331.4
prokineticin 1
chr8_+_66127043 1.42 ENST00000276573.11
ENST00000350034.4
ENST00000315962.9
tripartite motif containing 55
chr13_+_102656933 1.34 ENST00000650757.1
tripeptidyl peptidase 2
chr5_+_35856883 1.32 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr12_-_53207271 1.31 ENST00000552972.5
ENST00000422257.7
integrin subunit beta 7
chr15_-_55270383 1.30 ENST00000396307.6
RAB27A, member RAS oncogene family
chr21_-_39445719 1.28 ENST00000438404.5
ENST00000358268.6
ENST00000411566.5
ENST00000451131.1
ENST00000418018.5
ENST00000415863.5
ENST00000426783.5
ENST00000485895.6
ENST00000288350.8
ENST00000448288.6
ENST00000456017.5
ENST00000434281.5
lebercilin LCA5 like
chr2_+_1484663 1.26 ENST00000446278.5
ENST00000469607.3
thyroid peroxidase
chr3_+_88338451 1.21 ENST00000637986.2
casein kinase 2 subunit alpha' interacting protein
chr10_+_116324440 1.18 ENST00000333254.4
coiled-coil domain containing 172
chr15_-_55270280 1.18 ENST00000564609.5
RAB27A, member RAS oncogene family
chr6_+_106541111 1.17 ENST00000457437.1
crystallin beta-gamma domain containing 1
chr10_+_8054668 1.16 ENST00000379328.9
GATA binding protein 3
chr12_+_96912517 1.14 ENST00000457368.2
NEDD1 gamma-tubulin ring complex targeting factor
chr5_-_56116946 1.06 ENST00000434982.2
ankyrin repeat domain 55
chr5_-_41071314 1.06 ENST00000399564.5
maestro heat like repeat family member 2B
chr10_+_8054808 1.06 ENST00000346208.4
GATA binding protein 3
chr1_+_198638968 1.05 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr1_+_198639162 1.01 ENST00000418674.1
protein tyrosine phosphatase receptor type C
chr14_+_66486356 1.01 ENST00000636229.1
coiled-coil domain containing 196
chr7_-_36724457 0.99 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr15_+_81196871 0.98 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chr12_+_10307950 0.97 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr7_-_50093204 0.95 ENST00000419417.5
ENST00000046087.7
zona pellucida binding protein
chr7_-_38249572 0.94 ENST00000436911.6
T cell receptor gamma constant 2
chr8_+_65707041 0.93 ENST00000521247.6
ENST00000527155.5
mitochondrial fission regulator 1
chr5_-_55692620 0.93 ENST00000503817.5
ENST00000512595.5
solute carrier family 38 member 9
chr17_-_38841438 0.89 ENST00000614158.2
chromosome 17 open reading frame 98
chr3_-_120647018 0.88 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr14_+_22320128 0.87 ENST00000390468.1
T cell receptor alpha variable 41
chr6_+_87407965 0.86 ENST00000369562.9
cilia and flagella associated protein 206
chr9_+_76459152 0.85 ENST00000444201.6
ENST00000376730.5
glucosaminyl (N-acetyl) transferase 1
chr7_-_36724380 0.85 ENST00000617267.4
acyloxyacyl hydrolase
chr2_+_203936755 0.83 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr14_+_21990357 0.81 ENST00000390444.1
T cell receptor alpha variable 16
chr7_-_36724543 0.81 ENST00000612871.4
acyloxyacyl hydrolase
chr10_+_122910605 0.78 ENST00000368894.2
family with sequence similarity 24 member A
chrX_+_12867064 0.75 ENST00000380659.4
toll like receptor 7
chr14_+_67189393 0.73 ENST00000524532.5
ENST00000612183.4
ENST00000530728.5
family with sequence similarity 71 member D
chr12_+_10307818 0.72 ENST00000350274.9
ENST00000336164.9
killer cell lectin like receptor D1
chr14_+_30577752 0.72 ENST00000547532.5
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr19_+_14583076 0.72 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr8_+_7825137 0.72 ENST00000335186.3
defensin beta 106A
chr12_-_113335030 0.71 ENST00000552014.5
ENST00000680972.1
ENST00000548186.5
ENST00000202831.7
ENST00000549181.5
solute carrier family 8 member B1
chr8_-_33513077 0.71 ENST00000360742.9
ENST00000523305.1
ENST00000431156.7
ENST00000613904.1
TELO2 interacting protein 2
chr5_-_175968280 0.69 ENST00000513482.1
ENST00000265097.9
ENST00000628318.2
THO complex 3
chr5_+_160421847 0.68 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr20_-_33004307 0.68 ENST00000420875.5
ENST00000375519.2
ENST00000375523.7
ENST00000356173.8
Sad1 and UNC84 domain containing 5
chr12_+_85036310 0.68 ENST00000393212.7
ENST00000393217.7
leucine rich repeats and IQ motif containing 1
chr17_+_42773442 0.68 ENST00000253794.7
ENST00000590339.5
ENST00000589520.1
vacuolar protein sorting 25 homolog
chr8_-_7486400 0.66 ENST00000335479.2
defensin beta 106B
chr1_+_241532370 0.66 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr15_-_55270249 0.64 ENST00000568803.1
RAB27A, member RAS oncogene family
chr4_-_38782970 0.63 ENST00000502321.5
ENST00000308973.9
ENST00000613579.4
ENST00000361424.6
ENST00000622002.4
toll like receptor 10
chr17_+_56978111 0.62 ENST00000262288.8
ENST00000572710.5
ENST00000575395.5
ENST00000631024.1
serine carboxypeptidase 1
chr16_+_20764036 0.62 ENST00000440284.6
acyl-CoA synthetase medium chain family member 3
chr4_+_36281591 0.62 ENST00000639862.2
ENST00000357504.7
death domain containing 1
chr11_-_66677748 0.61 ENST00000525754.5
ENST00000531969.5
ENST00000524637.1
ENST00000531036.2
ENST00000310046.9
RNA binding motif protein 4B
chr9_-_114074969 0.61 ENST00000466610.6
alpha-1-microglobulin/bikunin precursor
chr7_+_120951116 0.61 ENST00000431467.1
inhibitor of growth family member 3
chrX_-_24027186 0.61 ENST00000328046.8
kelch like family member 15
chr7_+_106865474 0.61 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr7_+_128709052 0.60 ENST00000485070.5
family with sequence similarity 71 member F1
chr6_-_44265541 0.60 ENST00000619360.6
NFKB inhibitor epsilon
chr15_+_44736522 0.59 ENST00000329464.9
ENST00000558329.5
ENST00000560442.5
ENST00000561043.5
tripartite motif containing 69
chr1_+_100363118 0.59 ENST00000455467.6
cell division cycle 14A
chr5_-_115296610 0.58 ENST00000379611.10
ENST00000506442.5
coiled-coil domain containing 112
chr1_+_51102221 0.56 ENST00000648827.1
ENST00000371759.7
chromosome 1 open reading frame 185
chr7_-_93148345 0.54 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr5_+_69565122 0.54 ENST00000507595.1
GTF2H2 family member C
chr12_-_68302872 0.53 ENST00000539972.5
Mdm1 nuclear protein
chr13_-_100588731 0.53 ENST00000471912.1
ENST00000683975.1
gamma-glutamylamine cyclotransferase
chr17_-_3513768 0.52 ENST00000570318.1
ENST00000541913.5
spermatogenesis associated 22
chr8_-_37940103 0.52 ENST00000524298.1
ENST00000307599.5
glutamic-oxaloacetic transaminase 1 like 1
chr1_+_51102238 0.51 ENST00000467127.5
chromosome 1 open reading frame 185
chr14_+_39233884 0.51 ENST00000553728.1
MIA SH3 domain ER export factor 2
chr19_-_44500503 0.50 ENST00000587047.1
ENST00000391956.8
ENST00000221327.8
ENST00000592529.6
ENST00000591064.1
zinc finger protein 180
chr9_-_15472732 0.50 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr4_+_73481737 0.49 ENST00000226355.5
afamin
chr4_+_94207596 0.47 ENST00000359052.8
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_207104287 0.47 ENST00000421786.5
complement component 4 binding protein alpha
chr16_+_20806424 0.46 ENST00000568894.5
RNA exonuclease 5
chr1_+_174799895 0.44 ENST00000489615.5
RAB GTPase activating protein 1 like
chr6_+_25962792 0.44 ENST00000357085.5
tripartite motif containing 38
chr17_-_445939 0.43 ENST00000329099.4
refilin B
chr15_+_44736556 0.43 ENST00000338264.8
tripartite motif containing 69
chr5_+_172194172 0.42 ENST00000398186.5
EF-hand calcium binding domain 9
chr14_+_22096017 0.42 ENST00000390452.2
T cell receptor delta variable 1
chrX_+_88749318 0.41 ENST00000614120.1
CPX chromosome region candidate 1
chr6_+_135851681 0.41 ENST00000308191.11
phosphodiesterase 7B
chr5_+_76875177 0.41 ENST00000613039.1
S100 calcium binding protein Z
chr4_+_80335717 0.41 ENST00000358105.8
ENST00000508675.1
cilia and flagella associated protein 299
chr19_+_4153616 0.40 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr10_+_113125536 0.40 ENST00000349937.7
transcription factor 7 like 2
chr5_-_55692731 0.40 ENST00000502247.1
solute carrier family 38 member 9
chr2_+_102001966 0.40 ENST00000457817.5
interleukin 1 receptor type 2
chr20_-_56005466 0.39 ENST00000064571.3
cerebellin 4 precursor
chr2_+_89862438 0.39 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr5_+_156850292 0.39 ENST00000522232.3
PPP1R2 family member B
chr12_+_133080875 0.38 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr22_+_28772664 0.38 ENST00000448492.6
ENST00000421503.6
ENST00000249064.9
ENST00000444523.1
coiled-coil domain containing 117
chr12_+_57772942 0.37 ENST00000546504.1
novel protein
chr2_+_191678967 0.36 ENST00000435931.1
nucleic acid binding protein 1
chr6_+_42782020 0.36 ENST00000314073.9
BRD4 interacting chromatin remodeling complex associated protein like
chr6_-_165309598 0.36 ENST00000230301.9
chromosome 6 open reading frame 118
chr16_+_20806439 0.36 ENST00000568046.5
RNA exonuclease 5
chr6_+_73461578 0.34 ENST00000415954.6
ENST00000681204.1
ENST00000680686.1
ENST00000521156.6
ENST00000498286.6
ENST00000370305.5
ENST00000370300.8
mitochondrial tRNA translation optimization 1
chr1_+_33081145 0.32 ENST00000294517.11
ENST00000373443.7
antizyme inhibitor 2
chr16_-_18896874 0.32 ENST00000565324.5
ENST00000561947.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr17_-_59151794 0.32 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr19_+_21082190 0.31 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
zinc finger protein 714
chr17_-_39451243 0.31 ENST00000300651.11
ENST00000394287.7
mediator complex subunit 1
chr5_-_43397159 0.31 ENST00000513525.1
C-C motif chemokine ligand 28
chr7_-_108130349 0.31 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chr7_-_105269007 0.30 ENST00000357311.7
SRSF protein kinase 2
chr2_-_89010515 0.29 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr2_-_229923163 0.29 ENST00000435716.5
thyroid hormone receptor interactor 12
chr12_+_57454674 0.29 ENST00000547970.1
inhibin subunit beta E
chr12_+_21131187 0.29 ENST00000256958.3
solute carrier organic anion transporter family member 1B1
chr16_+_81779279 0.29 ENST00000564138.6
phospholipase C gamma 2
chr22_+_24011192 0.28 ENST00000454754.5
ENST00000263119.10
ENST00000617531.4
calcineurin binding protein 1
chr4_-_39032343 0.28 ENST00000381938.4
transmembrane protein 156
chr12_-_121669646 0.28 ENST00000355329.7
MORN repeat containing 3
chr2_-_206086057 0.27 ENST00000403263.6
INO80 complex subunit D
chr20_-_18497218 0.27 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr10_+_110005804 0.27 ENST00000360162.7
adducin 3
chr10_+_7703340 0.26 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr2_-_89320146 0.26 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr11_-_64777751 0.26 ENST00000433274.6
ENST00000432725.1
splicing factor 1
chr3_-_134250831 0.26 ENST00000623711.4
receptor like tyrosine kinase
chr19_-_55831987 0.25 ENST00000592953.5
ENST00000589093.5
NLR family pyrin domain containing 11
chr19_+_57128643 0.25 ENST00000598197.1
ubiquitin specific peptidase 29
chr10_-_28334439 0.25 ENST00000441595.2
membrane palmitoylated protein 7
chrX_+_23908006 0.25 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr19_-_23687163 0.25 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
zinc finger protein 675
chr1_-_178869272 0.25 ENST00000444255.1
angiopoietin like 1
chr17_-_18363504 0.24 ENST00000583780.1
ENST00000316694.8
ENST00000352886.10
serine hydroxymethyltransferase 1
chr18_+_616672 0.24 ENST00000338387.11
clusterin like 1
chrX_-_115017569 0.24 ENST00000243213.2
interleukin 13 receptor subunit alpha 2
chr12_+_133181409 0.24 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
zinc finger protein 268
chr16_+_81037187 0.24 ENST00000564241.5
ENST00000565237.1
ATM interactor
chr2_-_177263471 0.24 ENST00000449627.1
nuclear factor, erythroid 2 like 2
chr6_+_32844789 0.23 ENST00000414474.5
proteasome 20S subunit beta 9
chr13_+_75549734 0.23 ENST00000563635.5
ENST00000377595.8
novel transcript
ubiquitin C-terminal hydrolase L3
chr6_+_27957241 0.23 ENST00000244623.1
olfactory receptor family 2 subfamily B member 6
chr8_+_73991345 0.23 ENST00000284818.7
ENST00000518893.1
lymphocyte antigen 96
chr18_+_616711 0.22 ENST00000579494.1
clusterin like 1
chrX_-_120878924 0.22 ENST00000613352.1
novel protein similar to cancer/testis antigen family 47, member A12 (CT47A12)
chr4_+_70242583 0.22 ENST00000304954.3
casein kappa
chr4_-_44651619 0.22 ENST00000415895.9
ENST00000332990.6
Yip1 domain family member 7
chr6_-_49744378 0.22 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr11_+_43358908 0.21 ENST00000039989.9
ENST00000299240.10
tetratricopeptide repeat domain 17
chr4_-_158173004 0.21 ENST00000585682.6
golgi associated kinase 1B
chr9_-_104536856 0.21 ENST00000641090.1
olfactory receptor family 13 subfamily C member 3
chr1_+_210328244 0.21 ENST00000541565.5
ENST00000413764.6
hedgehog acyltransferase
chr12_+_133181529 0.20 ENST00000541009.6
ENST00000592241.5
zinc finger protein 268
chr12_+_18262730 0.20 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr19_+_24087147 0.20 ENST00000611359.3
ENST00000616028.2
zinc finger protein 254
chr15_-_52652031 0.20 ENST00000546305.6
family with sequence similarity 214 member A
chr10_+_60778331 0.20 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr12_-_7503841 0.19 ENST00000359156.8
CD163 molecule
chr14_+_23258485 0.19 ENST00000399905.5
ENST00000470456.1
ring finger protein 212B
chr4_+_73740541 0.19 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr22_-_30505650 0.18 ENST00000381982.3
ENST00000255858.12
SEC14 like lipid binding 4
chr3_-_187139477 0.18 ENST00000455270.5
ENST00000296277.9
ribosomal protein L39 like
chr3_+_57890011 0.17 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr4_+_70397931 0.17 ENST00000399575.7
opiorphin prepropeptide
chr3_+_172754457 0.17 ENST00000441497.6
epithelial cell transforming 2
chr15_+_41286011 0.16 ENST00000661438.1
novel protein
chr10_+_7703300 0.16 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chr6_+_37929959 0.15 ENST00000373389.5
zinc finger AN1-type containing 3
chr2_-_1979755 0.15 ENST00000649587.1
myelin transcription factor 1 like
chr19_+_21082140 0.15 ENST00000616183.1
ENST00000596053.5
zinc finger protein 714
chr4_-_158173042 0.15 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr4_+_105710809 0.15 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr14_+_39233908 0.14 ENST00000280082.4
MIA SH3 domain ER export factor 2
chr3_+_40477107 0.14 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr9_+_129139382 0.14 ENST00000423100.5
ENST00000674648.1
protein phosphatase 2 phosphatase activator
novel protein
chr16_-_4767125 0.14 ENST00000219478.11
ENST00000545009.1
zinc finger protein 500
chr14_+_67364849 0.14 ENST00000555876.1
eukaryotic translation initiation factor 2 subunit alpha
chr19_-_52821631 0.13 ENST00000457749.7
ENST00000391783.6
zinc finger protein 28
chr2_-_206086272 0.13 ENST00000414320.1
INO80 complex subunit D
chr13_-_75366973 0.13 ENST00000648194.1
TBC1 domain family member 4
chr2_+_190469486 0.13 ENST00000444317.1
major facilitator superfamily domain containing 6
chr7_+_7567009 0.13 ENST00000433056.5
meiosis regulator for oocyte development
chr1_+_203802094 0.13 ENST00000675181.1
novel protein
chr4_-_139302516 0.13 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr4_-_82848843 0.13 ENST00000511338.1
SEC31 homolog A, COPII coat complex component
chr12_-_75511594 0.12 ENST00000438169.6
ENST00000229214.9
KRR1 small subunit processome component homolog
chr7_+_7566866 0.12 ENST00000405785.5
ENST00000340080.9
ENST00000433635.1
meiosis regulator for oocyte development
chr2_-_189583392 0.12 ENST00000440626.1
solute carrier family 40 member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.6 2.2 GO:2000734 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.4 3.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 2.1 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.3 1.7 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 2.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 0.5 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.2 3.4 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.7 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.4 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 1.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.3 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.4 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.5 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.7 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0015847 putrescine transport(GO:0015847)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.4 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.9 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.6 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 1.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 1.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.8 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:1903414 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.7 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036) regulation of store-operated calcium entry(GO:2001256)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.6 GO:0032329 serine transport(GO:0032329) D-amino acid transport(GO:0042940)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 1.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 1.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.7 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 2.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.6 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 1.7 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.1 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.2 GO:2000645 negative regulation of myelination(GO:0031642) negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.6 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.3 0.9 GO:0001534 radial spoke(GO:0001534)
0.2 0.7 GO:0000814 ESCRT II complex(GO:0000814)
0.2 3.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.3 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 2.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.7 GO:0032009 early phagosome(GO:0032009)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0044207 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.0 2.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 6.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.3 1.7 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 0.9 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
0.3 1.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 2.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 0.9 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.5 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.7 GO:0042806 fucose binding(GO:0042806)
0.1 3.1 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0019862 IgA binding(GO:0019862)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) mediator complex binding(GO:0036033)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.7 GO:0035197 siRNA binding(GO:0035197)
0.0 1.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 3.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 4.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.9 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)