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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for ZNF691

Z-value: 1.44

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Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ZNF691
ENSG00000164011.18 ZNF691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF691hg38_v1_chr1_+_42846573_42846640-0.038.8e-01Click!

Activity profile of ZNF691 motif

Sorted Z-values of ZNF691 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_26317950 5.75 ENST00000374213.3
CD52
CD52 molecule
chr22_+_22880706 4.34 ENST00000390319.2
IGLV3-1
immunoglobulin lambda variable 3-1
chr11_+_60455839 3.52 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
MS4A1
membrane spanning 4-domains A1
chr15_-_74433942 3.19 ENST00000543145.6
ENST00000261918.9
SEMA7A
semaphorin 7A (John Milton Hagen blood group)
chr2_-_85668172 2.87 ENST00000428225.5
ENST00000519937.7
SFTPB
surfactant protein B
chr3_+_46370854 2.59 ENST00000292303.4
CCR5
C-C motif chemokine receptor 5
chr19_-_17821505 2.44 ENST00000598577.1
ENST00000317306.8
ENST00000379695.5
INSL3
insulin like 3
chr1_+_27872536 2.30 ENST00000328928.11
ENST00000373921.8
ENST00000373925.5
ENST00000373927.7
ENST00000427466.1
ENST00000442118.5
THEMIS2
thymocyte selection associated family member 2
chr17_-_75844334 2.23 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
UNC13D
unc-13 homolog D
chr1_+_203765168 2.20 ENST00000367217.5
ENST00000442561.7
LAX1
lymphocyte transmembrane adaptor 1
chr20_-_1657762 2.16 ENST00000303415.7
ENST00000381583.6
SIRPG
signal regulatory protein gamma
chr12_-_51324091 2.14 ENST00000604560.6
BIN2
bridging integrator 2
chr12_-_51324652 2.00 ENST00000544402.5
BIN2
bridging integrator 2
chr12_-_51324164 1.83 ENST00000615107.6
BIN2
bridging integrator 2
chr12_-_51324138 1.82 ENST00000452142.7
BIN2
bridging integrator 2
chr3_-_172523460 1.67 ENST00000420541.6
TNFSF10
TNF superfamily member 10
chr3_-_172523423 1.62 ENST00000241261.7
TNFSF10
TNF superfamily member 10
chr11_+_102317542 1.60 ENST00000532808.5
BIRC3
baculoviral IAP repeat containing 3
chr6_+_31586269 1.53 ENST00000438075.7
LST1
leukocyte specific transcript 1
chr6_+_31586124 1.46 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr10_+_127907036 1.40 ENST00000254667.8
ENST00000442830.5
PTPRE
protein tyrosine phosphatase receptor type E
chr17_+_75610690 1.39 ENST00000642007.1
MYO15B
myosin XVB
chr2_+_68734773 1.35 ENST00000409202.8
ARHGAP25
Rho GTPase activating protein 25
chr7_+_142462882 1.34 ENST00000454561.2
TRBV5-4
T cell receptor beta variable 5-4
chr16_+_760728 1.33 ENST00000545450.7
ENST00000563941.5
ENST00000566549.5
MSLN
mesothelin
chr2_+_68734861 1.30 ENST00000467265.5
ARHGAP25
Rho GTPase activating protein 25
chr2_+_201233443 1.28 ENST00000392263.6
ENST00000264274.13
ENST00000432109.6
ENST00000264275.9
ENST00000450491.5
ENST00000440732.5
ENST00000392258.7
CASP8
caspase 8
chr5_-_132011811 1.23 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
ACSL6
acyl-CoA synthetase long chain family member 6
chr16_+_57628507 1.17 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
ADGRG1
adhesion G protein-coupled receptor G1
chr17_-_75843708 1.17 ENST00000590762.5
UNC13D
unc-13 homolog D
chr20_+_38304149 1.14 ENST00000262865.9
ENST00000642449.2
BPI
bactericidal permeability increasing protein
chr14_-_91867529 1.02 ENST00000435962.7
TC2N
tandem C2 domains, nuclear
chr17_-_75844533 0.95 ENST00000586108.1
UNC13D
unc-13 homolog D
chr17_+_77405070 0.95 ENST00000585930.5
SEPTIN9
septin 9
chr20_-_1588632 0.94 ENST00000262929.9
ENST00000567028.5
SIRPB1
ENSG00000260861.6
signal regulatory protein beta 1
novel protein, SIRPB1-SIRPD readthrough
chr5_-_179617581 0.94 ENST00000523449.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr16_+_84294823 0.93 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr15_-_40106609 0.91 ENST00000561360.5
BMF
Bcl2 modifying factor
chr8_+_27311620 0.90 ENST00000522338.5
PTK2B
protein tyrosine kinase 2 beta
chr4_-_82798735 0.88 ENST00000273908.4
ENST00000319540.9
SCD5
stearoyl-CoA desaturase 5
chr6_-_158819355 0.88 ENST00000367075.4
EZR
ezrin
chr9_-_132878262 0.86 ENST00000298545.4
AK8
adenylate kinase 8
chr9_-_120929160 0.85 ENST00000540010.1
TRAF1
TNF receptor associated factor 1
chr16_+_84294853 0.84 ENST00000219454.10
WFDC1
WAP four-disulfide core domain 1
chr11_+_121590388 0.83 ENST00000527934.1
SORL1
sortilin related receptor 1
chr21_+_14216145 0.80 ENST00000400577.4
RBM11
RNA binding motif protein 11
chr12_+_53461015 0.79 ENST00000553064.6
ENST00000547859.2
PCBP2
poly(rC) binding protein 2
chr5_-_179618032 0.76 ENST00000519033.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr1_+_178513103 0.76 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
TEX35
testis expressed 35
chr15_-_25863304 0.76 ENST00000555815.6
ENST00000673716.1
ATP10A
ATPase phospholipid transporting 10A (putative)
chr3_+_184181985 0.75 ENST00000442686.1
AP2M1
adaptor related protein complex 2 subunit mu 1
chr9_+_137077467 0.74 ENST00000409858.8
UAP1L1
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
chr17_+_47209035 0.68 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
MYL4
myosin light chain 4
chr1_-_183653307 0.66 ENST00000308641.6
APOBEC4
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr16_+_57628226 0.65 ENST00000562414.5
ENST00000561969.5
ENST00000563445.5
ENST00000565338.5
ENST00000567702.5
ADGRG1
adhesion G protein-coupled receptor G1
chr17_-_63931354 0.65 ENST00000647774.1
ENSG00000285947.1
novel protein
chrX_+_103215072 0.65 ENST00000372695.6
ENST00000372691.3
BEX4
brain expressed X-linked 4
chr2_+_201260496 0.64 ENST00000323492.11
CASP8
caspase 8
chr5_-_132011794 0.63 ENST00000650697.1
ACSL6
acyl-CoA synthetase long chain family member 6
chrX_+_103710907 0.63 ENST00000319560.7
TMEM31
transmembrane protein 31
chr11_+_44726811 0.62 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
TSPAN18
tetraspanin 18
chr11_+_67586104 0.61 ENST00000495996.1
GSTP1
glutathione S-transferase pi 1
chr9_+_132878873 0.61 ENST00000356311.10
ENST00000350499.6
SPACA9
sperm acrosome associated 9
chrX_-_63351308 0.61 ENST00000374884.3
SPIN4
spindlin family member 4
chr6_-_144008396 0.59 ENST00000354765.6
ENST00000416623.5
ENST00000649211.1
PLAGL1
PLAG1 like zinc finger 1
chr5_-_39074377 0.57 ENST00000514735.1
ENST00000357387.8
ENST00000296782.9
RICTOR
RPTOR independent companion of MTOR complex 2
chr12_+_94262521 0.57 ENST00000545312.1
PLXNC1
plexin C1
chr1_-_233295712 0.57 ENST00000258229.14
PCNX2
pecanex 2
chr20_-_35147285 0.56 ENST00000374491.3
ENST00000374492.8
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
chr2_+_105851748 0.56 ENST00000425756.1
ENST00000393349.2
NCK2
NCK adaptor protein 2
chr15_-_58279245 0.56 ENST00000558231.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr22_-_31662430 0.53 ENST00000439502.6
PISD
phosphatidylserine decarboxylase
chr20_-_63572455 0.53 ENST00000467148.1
HELZ2
helicase with zinc finger 2
chr3_-_195247851 0.52 ENST00000429994.5
XXYLT1
xyloside xylosyltransferase 1
chr9_+_132978687 0.44 ENST00000372122.4
ENST00000372123.5
GFI1B
growth factor independent 1B transcriptional repressor
chr8_+_141416141 0.43 ENST00000680615.1
PTP4A3
protein tyrosine phosphatase 4A3
chr14_+_49893055 0.42 ENST00000298316.7
ARF6
ADP ribosylation factor 6
chr12_-_132687307 0.41 ENST00000535270.5
ENST00000320574.10
POLE
DNA polymerase epsilon, catalytic subunit
chr3_-_167734510 0.38 ENST00000475915.6
ENST00000462725.6
ENST00000461494.5
PDCD10
programmed cell death 10
chr16_-_53703883 0.38 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1L
RPGRIP1 like
chr8_+_141416078 0.37 ENST00000349124.3
PTP4A3
protein tyrosine phosphatase 4A3
chr19_+_9324165 0.37 ENST00000446085.8
ENST00000603656.5
ENST00000541595.6
ENST00000592504.5
ENST00000585352.5
ENST00000317221.11
ENST00000603380.6
ENST00000586255.5
ENST00000592896.5
ENST00000605750.5
ENST00000589208.1
ENST00000592298.5
ENST00000585377.5
ENST00000393883.6
ENST00000588124.1
ZNF559-ZNF177
ZNF559
ZNF559-ZNF177 readthrough
zinc finger protein 559
chr13_-_52129051 0.36 ENST00000652119.1
ENST00000647945.1
ENST00000355568.8
NEK5
NIMA related kinase 5
chr11_-_65122057 0.36 ENST00000531743.5
ENST00000527548.5
ENST00000526555.5
ENST00000529639.6
ENST00000279259.7
FAU
FAU ubiquitin like and ribosomal protein S30 fusion
chr17_-_40665121 0.35 ENST00000394052.5
KRT222
keratin 222
chr17_+_82458733 0.35 ENST00000309794.16
ENST00000577410.2
NARF
nuclear prelamin A recognition factor
chr12_-_108827384 0.34 ENST00000326470.9
SSH1
slingshot protein phosphatase 1
chr10_-_97498378 0.33 ENST00000327238.14
ENST00000437002.5
ENST00000438925.7
ENST00000422685.5
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component
chr3_-_167734465 0.31 ENST00000487947.6
PDCD10
programmed cell death 10
chr1_-_144373659 0.31 ENST00000581164.1
PPIAL4E
peptidylprolyl isomerase A like 4E
chr19_-_49808639 0.30 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr9_+_136658854 0.29 ENST00000371699.5
EGFL7
EGF like domain multiple 7
chr20_-_47348072 0.28 ENST00000441977.1
ZMYND8
zinc finger MYND-type containing 8
chr16_-_53703810 0.28 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1L
RPGRIP1 like
chr17_+_82458649 0.27 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
NARF
nuclear prelamin A recognition factor
chr8_+_98426943 0.25 ENST00000287042.5
KCNS2
potassium voltage-gated channel modifier subfamily S member 2
chr1_+_144592868 0.25 ENST00000581138.3
PPIAL4F
peptidylprolyl isomerase A like 4F
chr17_+_82458174 0.25 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
NARF
nuclear prelamin A recognition factor
chr4_+_663696 0.25 ENST00000471824.6
PDE6B
phosphodiesterase 6B
chr17_+_45844875 0.24 ENST00000329196.7
SPPL2C
signal peptide peptidase like 2C
chr10_-_89251768 0.24 ENST00000336233.10
LIPA
lipase A, lysosomal acid type
chr3_+_44555185 0.23 ENST00000426540.6
ENST00000431636.5
ENST00000341840.7
ENST00000273320.7
ZKSCAN7
zinc finger with KRAB and SCAN domains 7
chr22_-_31662180 0.23 ENST00000435900.5
PISD
phosphatidylserine decarboxylase
chr12_-_10453330 0.20 ENST00000347831.9
ENST00000359151.8
KLRC1
killer cell lectin like receptor C1
chr17_+_81528370 0.20 ENST00000417245.7
ENST00000334850.7
FSCN2
fascin actin-bundling protein 2, retinal
chr17_+_75234704 0.20 ENST00000579838.1
NUP85
nucleoporin 85
chr9_+_128685062 0.20 ENST00000409104.7
SET
SET nuclear proto-oncogene
chrX_-_152769677 0.19 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGEA6
MAGE family member A6
chr5_-_175968280 0.18 ENST00000513482.1
ENST00000265097.9
ENST00000628318.2
THOC3
THO complex 3
chr16_+_84294944 0.17 ENST00000613603.1
WFDC1
WAP four-disulfide core domain 1
chr2_-_219243577 0.16 ENST00000409640.5
GLB1L
galactosidase beta 1 like
chr3_-_167734832 0.16 ENST00000464360.5
ENST00000492139.5
ENST00000471885.5
ENST00000392750.7
ENST00000470131.5
PDCD10
programmed cell death 10
chr9_+_113505256 0.14 ENST00000374136.5
RGS3
regulator of G protein signaling 3
chr20_+_64255695 0.13 ENST00000299468.11
PCMTD2
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr19_+_58544447 0.13 ENST00000594806.5
ENST00000341753.10
TRIM28
tripartite motif containing 28
chr1_-_146344790 0.13 ENST00000584068.3
PPIAL4H
peptidylprolyl isomerase A like 4H
chr17_-_3513768 0.12 ENST00000570318.1
ENST00000541913.5
SPATA22
spermatogenesis associated 22
chr9_+_81988772 0.09 ENST00000344803.3
SPATA31D1
SPATA31 subfamily D member 1
chr2_-_202871611 0.08 ENST00000392237.6
ENST00000416760.5
ENST00000412210.5
ICA1L
islet cell autoantigen 1 like
chr6_-_144008364 0.08 ENST00000625622.2
PLAGL1
PLAG1 like zinc finger 1
chr1_-_16437416 0.06 ENST00000375577.5
ENST00000335496.5
SPATA21
spermatogenesis associated 21
chr11_-_36598221 0.04 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
RAG2
recombination activating 2
chr8_-_28490220 0.03 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
FBXO16
F-box protein 16
chr14_+_22501542 0.02 ENST00000390498.1
TRAJ39
T cell receptor alpha joining 39
chr5_-_177462379 0.01 ENST00000512501.1
DBN1
drebrin 1
chr14_-_20802402 0.01 ENST00000412779.2
RNASE1
ribonuclease A family member 1, pancreatic

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0002432 granuloma formation(GO:0002432)
0.4 1.9 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.3 0.8 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 2.6 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 0.6 GO:0035732 nitric oxide storage(GO:0035732)
0.2 7.8 GO:0097320 membrane tubulation(GO:0097320)
0.2 0.6 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.9 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.9 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 3.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 5.7 GO:0045730 respiratory burst(GO:0045730)
0.1 3.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 1.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 2.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.9 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 4.3 GO:0030449 regulation of complement activation(GO:0030449)
0.0 3.1 GO:0042100 B cell proliferation(GO:0042100)
0.0 1.5 GO:0021591 ventricular system development(GO:0021591)
0.0 2.4 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 3.0 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 3.0 GO:0061041 regulation of wound healing(GO:0061041)
0.0 2.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 2.9 GO:0097208 alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486)
0.2 7.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.6 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 1.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 1.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 10.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 5.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.7 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 0.6 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.2 0.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 2.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.9 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 3.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.8 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.8 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 4.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 2.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.2 GO:0023023 MHC protein complex binding(GO:0023023)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 4.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 4.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 2.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 5.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events