Project

avrg: young vs old, Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for ZNF8

Z-value: 0.41

Motif logo

logo of

Transcription factors associated with ZNF8

Gene Symbol Gene ID Gene Info
ZNF8
ENSG00000278129.2 ZNF8
ZNF8
ENSG00000278129.2 ZNF8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF8hg38_v1_chr19_+_58278948_582789920.019.7e-01Click!

Activity profile of ZNF8 motif

Sorted Z-values of ZNF8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_55140922 2.54 ENST00000589745.5
TNNT1
troponin T1, slow skeletal type
chr12_-_46269105 2.46 ENST00000546893.5
SLC38A1
solute carrier family 38 member 1
chr12_-_46268989 2.31 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
SLC38A1
solute carrier family 38 member 1
chr6_+_18155399 1.48 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
KDM1B
lysine demethylase 1B
chr6_+_18155329 1.19 ENST00000546309.6
KDM1B
lysine demethylase 1B
chr3_+_50617390 1.00 ENST00000457064.1
MAPKAPK3
MAPK activated protein kinase 3
chr11_+_13668702 0.97 ENST00000532701.1
FAR1
fatty acyl-CoA reductase 1
chr2_+_219491867 0.90 ENST00000412982.5
ENSG00000286143.1
novel protein
chr6_-_116279837 0.83 ENST00000368608.4
TSPYL1
TSPY like 1
chr13_+_52455429 0.82 ENST00000468284.1
ENST00000378034.7
ENST00000378037.9
ENST00000258607.10
CKAP2
cytoskeleton associated protein 2
chr2_-_239400949 0.80 ENST00000345617.7
HDAC4
histone deacetylase 4
chr2_-_239400991 0.75 ENST00000543185.6
HDAC4
histone deacetylase 4
chr9_-_37576365 0.72 ENST00000432825.7
FBXO10
F-box protein 10
chr4_-_185425941 0.69 ENST00000264689.11
ENST00000505357.1
UFSP2
UFM1 specific peptidase 2
chr11_+_13668653 0.67 ENST00000354817.8
FAR1
fatty acyl-CoA reductase 1
chr3_-_57079287 0.63 ENST00000338458.8
ENST00000468727.5
ARHGEF3
Rho guanine nucleotide exchange factor 3
chr17_+_35809474 0.59 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TAF15
TATA-box binding protein associated factor 15
chr12_-_122266425 0.57 ENST00000643696.1
ENST00000267199.9
VPS33A
VPS33A core subunit of CORVET and HOPS complexes
chrX_-_93673558 0.56 ENST00000475430.2
ENST00000373079.4
NAP1L3
nucleosome assembly protein 1 like 3
chr3_-_9952337 0.54 ENST00000411976.2
ENST00000412055.6
PRRT3
proline rich transmembrane protein 3
chr4_-_52020332 0.52 ENST00000682860.1
LRRC66
leucine rich repeat containing 66
chr10_+_988425 0.50 ENST00000360803.9
GTPBP4
GTP binding protein 4
chr16_+_21953288 0.49 ENST00000630839.2
UQCRC2
ubiquinol-cytochrome c reductase core protein 2
chr17_+_50547089 0.47 ENST00000619622.4
ENST00000356488.8
ENST00000006658.11
SPATA20
spermatogenesis associated 20
chr9_+_32551670 0.47 ENST00000450093.3
SMIM27
small integral membrane protein 27
chr17_-_28842727 0.45 ENST00000583307.6
ENST00000581229.6
ENST00000582266.6
ENST00000577376.6
ENST00000577682.6
ENST00000581407.6
ENST00000341217.7
ENST00000583522.6
FAM222B
family with sequence similarity 222 member B
chr4_+_169620509 0.45 ENST00000347613.8
CLCN3
chloride voltage-gated channel 3
chr7_-_75073844 0.42 ENST00000614461.4
ENST00000618035.4
RCC1L
RCC1 like
chr9_+_93263948 0.42 ENST00000448251.5
WNK2
WNK lysine deficient protein kinase 2
chr3_-_46717855 0.41 ENST00000315170.13
PRSS50
serine protease 50
chr3_-_45958654 0.40 ENST00000438446.1
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1
chr20_+_38748448 0.39 ENST00000243903.6
ACTR5
actin related protein 5
chr4_+_169620527 0.35 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
CLCN3
chloride voltage-gated channel 3
chr6_-_31795475 0.35 ENST00000440048.1
VARS1
valyl-tRNA synthetase 1
chr4_-_76148382 0.35 ENST00000264883.8
ENST00000514987.5
ENST00000514901.5
NUP54
nucleoporin 54
chr12_-_122266410 0.32 ENST00000451053.3
VPS33A
VPS33A core subunit of CORVET and HOPS complexes
chr16_+_21953341 0.32 ENST00000268379.9
ENST00000561553.5
ENST00000565331.5
UQCRC2
ubiquinol-cytochrome c reductase core protein 2
chr2_-_105329685 0.31 ENST00000393359.7
TGFBRAP1
transforming growth factor beta receptor associated protein 1
chr13_-_25287457 0.31 ENST00000381801.6
MTMR6
myotubularin related protein 6
chr2_+_171434196 0.31 ENST00000375255.8
ENST00000539783.5
DCAF17
DDB1 and CUL4 associated factor 17
chr1_-_54801161 0.30 ENST00000371274.8
TTC22
tetratricopeptide repeat domain 22
chr11_-_46617170 0.27 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr7_-_100100716 0.26 ENST00000354230.7
ENST00000425308.5
MCM7
minichromosome maintenance complex component 7
chr1_-_54801290 0.26 ENST00000371276.9
TTC22
tetratricopeptide repeat domain 22
chr22_+_29767351 0.25 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_-_186375671 0.25 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr6_+_44246166 0.25 ENST00000620073.4
HSP90AB1
heat shock protein 90 alpha family class B member 1
chr6_-_18155053 0.24 ENST00000309983.5
TPMT
thiopurine S-methyltransferase
chrX_+_1268828 0.23 ENST00000432318.8
ENST00000381509.8
ENST00000494969.7
ENST00000355805.7
ENST00000355432.8
CSF2RA
colony stimulating factor 2 receptor subunit alpha
chr8_+_38387120 0.20 ENST00000526356.1
LETM2
leucine zipper and EF-hand containing transmembrane protein 2
chr1_-_100249815 0.19 ENST00000370131.3
ENST00000681617.1
ENST00000681780.1
ENST00000370132.8
DBT
dihydrolipoamide branched chain transacylase E2
chr1_-_70205531 0.19 ENST00000370952.4
LRRC40
leucine rich repeat containing 40
chr13_+_21176629 0.17 ENST00000309594.5
MRPL57
mitochondrial ribosomal protein L57
chr5_+_139341826 0.16 ENST00000265192.9
PAIP2
poly(A) binding protein interacting protein 2
chrX_+_129779930 0.16 ENST00000356892.4
SASH3
SAM and SH3 domain containing 3
chr3_+_49199477 0.16 ENST00000452691.7
ENST00000366429.2
IHO1
interactor of HORMAD1 1
chr16_-_53503192 0.15 ENST00000568596.5
ENST00000394657.12
ENST00000570004.5
ENST00000564497.1
ENST00000300245.8
AKTIP
AKT interacting protein
chr9_-_32552553 0.15 ENST00000379858.1
ENST00000360538.7
ENST00000681750.1
ENST00000680198.1
TOPORS
ENSG00000288684.1
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
novel protein
chr2_+_169069537 0.15 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
DHRS9
dehydrogenase/reductase 9
chr19_+_37507129 0.14 ENST00000586138.5
ENST00000588578.5
ENST00000587986.5
ZNF793
zinc finger protein 793
chr5_+_103120314 0.14 ENST00000613674.4
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr13_+_36819214 0.13 ENST00000255476.3
RFXAP
regulatory factor X associated protein
chr16_+_68539213 0.13 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90
ZFP90 zinc finger protein
chr17_+_77185210 0.11 ENST00000431431.6
SEC14L1
SEC14 like lipid binding 1
chr14_-_100903696 0.08 ENST00000649591.1
RTL1
retrotransposon Gag like 1
chr5_-_94111627 0.08 ENST00000505869.5
ENST00000395965.8
ENST00000509163.5
FAM172A
family with sequence similarity 172 member A
chr5_+_139341875 0.07 ENST00000511706.5
PAIP2
poly(A) binding protein interacting protein 2
chr22_-_29766934 0.06 ENST00000344318.4
ZMAT5
zinc finger matrin-type 5
chr22_-_38656353 0.06 ENST00000535113.7
FAM227A
family with sequence similarity 227 member A
chr17_-_58514617 0.06 ENST00000682306.1
MTMR4
myotubularin related protein 4
chr9_-_37576336 0.06 ENST00000541607.1
FBXO10
F-box protein 10
chr2_+_130182224 0.04 ENST00000651060.1
ENST00000409255.1
ENST00000281871.11
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr1_-_235128819 0.03 ENST00000366607.5
TOMM20
translocase of outer mitochondrial membrane 20
chr8_+_26291758 0.03 ENST00000522535.5
ENST00000665949.1
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
chr5_-_138575359 0.03 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
HSPA9
heat shock protein family A (Hsp70) member 9
chr2_+_118096418 0.03 ENST00000614681.1
INSIG2
insulin induced gene 2
chr1_-_22965338 0.02 ENST00000426928.6
LACTBL1
lactamase beta like 1
chr13_-_21176540 0.02 ENST00000400018.7
ENST00000314759.6
SKA3
spindle and kinetochore associated complex subunit 3
chr5_+_103120264 0.02 ENST00000358359.8
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr2_-_171433950 0.01 ENST00000375258.9
ENST00000442541.1
ENST00000392599.6
METTL8
methyltransferase like 8
chrX_+_130401962 0.01 ENST00000305536.11
ENST00000370947.1
RBMX2
RNA binding motif protein X-linked 2
chr1_-_228109255 0.01 ENST00000483159.1
ENST00000366744.5
ENST00000348259.9
ENST00000495434.1
ENST00000295008.8
ENST00000366731.9
ENST00000366746.7
ENST00000366747.7
ENST00000336520.8
ENST00000391867.8
ENST00000457264.5
ENST00000464148.2
ENST00000336300.9
ENST00000430433.5
MRPL55
mitochondrial ribosomal protein L55

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3 2.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.5 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 2.7 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.8 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.1 4.8 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 0.2 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.0 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.9 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 GO:0005861 troponin complex(GO:0005861)
0.1 2.7 GO:0000786 nucleosome(GO:0000786)
0.1 0.2 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.1 1.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0030897 HOPS complex(GO:0030897)
0.0 1.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.6 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 2.5 GO:0031014 troponin T binding(GO:0031014)
0.2 1.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 4.8 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 0.2 GO:0002135 CTP binding(GO:0002135)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein