Motif ID: Rela_Rel_Nfkb1
Z-value: 1.289



Transcription factors associated with Rela_Rel_Nfkb1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nfkb1 | ENSMUSG00000028163.11 | Nfkb1 |
Rel | ENSMUSG00000020275.8 | Rel |
Rela | ENSMUSG00000024927.7 | Rela |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nfkb1 | mm10_v2_chr3_-_135608221_135608290 | 0.84 | 1.2e-05 | Click! |
Rela | mm10_v2_chr19_+_5637475_5637486 | 0.30 | 2.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 3.8 | GO:0097350 | neutrophil clearance(GO:0097350) |
1.2 | 8.4 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.9 | 2.8 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.7 | 1.3 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
0.6 | 1.8 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
0.6 | 1.8 | GO:0072554 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
0.5 | 2.2 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.5 | 1.6 | GO:0090403 | regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) oxidative stress-induced premature senescence(GO:0090403) |
0.5 | 1.9 | GO:0030091 | protein repair(GO:0030091) |
0.4 | 1.8 | GO:1903416 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416) |
0.4 | 0.8 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
0.4 | 1.2 | GO:0016115 | terpenoid catabolic process(GO:0016115) |
0.4 | 1.2 | GO:0070103 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.4 | 1.9 | GO:0015671 | oxygen transport(GO:0015671) |
0.4 | 1.4 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.4 | 1.8 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137) |
0.3 | 3.0 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.3 | 2.0 | GO:0007296 | vitellogenesis(GO:0007296) |
0.3 | 3.3 | GO:0048733 | sebaceous gland development(GO:0048733) |
0.3 | 1.1 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.3 | 1.1 | GO:1900150 | regulation of defense response to fungus(GO:1900150) |
0.3 | 0.8 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
0.3 | 6.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.3 | 4.1 | GO:0003334 | keratinocyte development(GO:0003334) |
0.3 | 3.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.2 | 1.5 | GO:0070094 | positive regulation of glucagon secretion(GO:0070094) |
0.2 | 0.7 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356) |
0.2 | 1.2 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.2 | 1.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
0.2 | 0.7 | GO:0060023 | soft palate development(GO:0060023) |
0.2 | 0.6 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.2 | 0.6 | GO:0071579 | regulation of zinc ion transport(GO:0071579) |
0.2 | 0.4 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
0.2 | 1.5 | GO:0098535 | de novo centriole assembly(GO:0098535) |
0.2 | 1.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.2 | 0.6 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.2 | 1.0 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.2 | 0.8 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
0.2 | 1.5 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
0.2 | 0.6 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
0.2 | 0.7 | GO:0070859 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
0.2 | 0.7 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.2 | 0.7 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.2 | 0.5 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.2 | 1.4 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
0.2 | 1.5 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
0.1 | 1.6 | GO:0060056 | mammary gland involution(GO:0060056) |
0.1 | 0.7 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.1 | 1.7 | GO:2000254 | regulation of male germ cell proliferation(GO:2000254) |
0.1 | 0.4 | GO:0090135 | actin filament branching(GO:0090135) negative regulation of phospholipase C activity(GO:1900275) |
0.1 | 0.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.1 | 0.8 | GO:0072553 | terminal button organization(GO:0072553) |
0.1 | 0.6 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.1 | 0.8 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.1 | 0.6 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.1 | 0.4 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.1 | 1.5 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.1 | 0.2 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.1 | 0.4 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
0.1 | 0.4 | GO:1904170 | regulation of bleb assembly(GO:1904170) |
0.1 | 0.5 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
0.1 | 0.4 | GO:1900060 | negative regulation of ceramide biosynthetic process(GO:1900060) |
0.1 | 1.9 | GO:0002467 | germinal center formation(GO:0002467) |
0.1 | 0.6 | GO:1990839 | response to endothelin(GO:1990839) |
0.1 | 0.4 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.1 | 0.4 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269) |
0.1 | 0.2 | GO:0035622 | intrahepatic bile duct development(GO:0035622) |
0.1 | 0.4 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
0.1 | 0.3 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.1 | 0.4 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
0.1 | 1.4 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.8 | GO:0042095 | interferon-gamma biosynthetic process(GO:0042095) |
0.1 | 0.6 | GO:0051013 | microtubule severing(GO:0051013) |
0.1 | 0.5 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
0.1 | 1.6 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 0.7 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.1 | 0.5 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
0.1 | 0.3 | GO:2000510 | regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.1 | 1.1 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.1 | 1.1 | GO:0061436 | establishment of skin barrier(GO:0061436) |
0.1 | 0.3 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
0.1 | 0.7 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.1 | 0.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 0.4 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.1 | 1.7 | GO:0038092 | nodal signaling pathway(GO:0038092) |
0.1 | 0.3 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
0.1 | 0.8 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.2 | GO:0060664 | epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664) |
0.1 | 0.7 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.1 | 0.7 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 1.5 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
0.1 | 0.3 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
0.1 | 0.2 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.1 | 0.3 | GO:0035553 | oxidative single-stranded RNA demethylation(GO:0035553) |
0.1 | 0.5 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) histone H3-K27 demethylation(GO:0071557) |
0.1 | 0.2 | GO:2000334 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
0.1 | 0.5 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
0.1 | 0.5 | GO:0048102 | autophagic cell death(GO:0048102) |
0.1 | 0.2 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.1 | 1.0 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.1 | 0.6 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
0.1 | 0.3 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 1.3 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
0.1 | 0.5 | GO:0048625 | embryonic hindgut morphogenesis(GO:0048619) myoblast fate commitment(GO:0048625) |
0.1 | 0.3 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
0.1 | 0.8 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.1 | 0.6 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.1 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
0.1 | 4.2 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.1 | 0.9 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.1 | 0.2 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) |
0.1 | 0.7 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
0.1 | 0.5 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.1 | 0.3 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.1 | 0.9 | GO:0003338 | metanephros morphogenesis(GO:0003338) |
0.1 | 0.1 | GO:0060737 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
0.1 | 0.7 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.5 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
0.1 | 1.2 | GO:0001709 | cell fate determination(GO:0001709) |
0.1 | 0.6 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 2.6 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
0.0 | 1.3 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 0.1 | GO:0046101 | hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) |
0.0 | 0.5 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.4 | GO:0019884 | antigen processing and presentation of exogenous antigen(GO:0019884) |
0.0 | 0.7 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.2 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.0 | 1.6 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.1 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
0.0 | 0.2 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 2.6 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
0.0 | 0.5 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
0.0 | 0.4 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.0 | 0.4 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.0 | 0.2 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.0 | 0.2 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
0.0 | 0.2 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.0 | 0.4 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.8 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
0.0 | 0.7 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.5 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
0.0 | 0.2 | GO:0040031 | snRNA modification(GO:0040031) |
0.0 | 0.2 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
0.0 | 0.2 | GO:0030223 | neutrophil differentiation(GO:0030223) |
0.0 | 0.4 | GO:0045830 | positive regulation of isotype switching(GO:0045830) |
0.0 | 0.6 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 0.2 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
0.0 | 0.6 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.3 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.0 | 0.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.2 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.0 | 0.1 | GO:0090282 | positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282) |
0.0 | 0.8 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.0 | 0.1 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
0.0 | 0.2 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
0.0 | 0.3 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.1 | GO:0048539 | bone marrow development(GO:0048539) |
0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.3 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 0.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.3 | GO:0070475 | rRNA base methylation(GO:0070475) |
0.0 | 0.1 | GO:0007494 | midgut development(GO:0007494) vein smooth muscle contraction(GO:0014826) |
0.0 | 0.1 | GO:0030043 | actin filament fragmentation(GO:0030043) |
0.0 | 1.1 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 0.1 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.2 | GO:1903912 | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912) |
0.0 | 0.1 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.0 | 0.4 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.0 | 0.1 | GO:0015867 | ATP transport(GO:0015867) |
0.0 | 0.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.0 | 0.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.1 | GO:2000318 | positive regulation of T-helper 17 type immune response(GO:2000318) |
0.0 | 1.8 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
0.0 | 0.2 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.0 | 0.1 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.0 | 0.4 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
0.0 | 0.3 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.0 | 0.2 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 1.2 | GO:0035082 | axoneme assembly(GO:0035082) |
0.0 | 0.2 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
0.0 | 0.1 | GO:0045911 | positive regulation of DNA recombination(GO:0045911) |
0.0 | 0.2 | GO:0060192 | regulation of lipoprotein lipase activity(GO:0051004) negative regulation of lipase activity(GO:0060192) |
0.0 | 0.1 | GO:1903232 | melanosome assembly(GO:1903232) |
0.0 | 0.2 | GO:0071549 | response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549) |
0.0 | 0.1 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
0.0 | 0.1 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
0.0 | 0.1 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
0.0 | 0.2 | GO:0032494 | response to peptidoglycan(GO:0032494) |
0.0 | 0.2 | GO:0070633 | transepithelial transport(GO:0070633) |
0.0 | 0.4 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
0.0 | 0.2 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.0 | 2.0 | GO:2000045 | regulation of G1/S transition of mitotic cell cycle(GO:2000045) |
0.0 | 1.1 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.2 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
0.0 | 2.2 | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731) |
0.0 | 0.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
0.0 | 0.1 | GO:0007603 | phototransduction, visible light(GO:0007603) |
0.0 | 0.2 | GO:0031584 | activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176) |
0.0 | 1.1 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
0.0 | 0.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
0.0 | 0.4 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.0 | 0.9 | GO:0043966 | histone H3 acetylation(GO:0043966) |
0.0 | 0.4 | GO:0016180 | snRNA processing(GO:0016180) |
0.0 | 0.2 | GO:0048096 | nucleosome disassembly(GO:0006337) chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 0.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.3 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.0 | 0.1 | GO:0032506 | cytokinetic process(GO:0032506) |
0.0 | 0.5 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.1 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
0.0 | 2.1 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
0.0 | 0.1 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.0 | 0.2 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.0 | GO:0046133 | pyrimidine ribonucleoside catabolic process(GO:0046133) |
0.0 | 0.3 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.1 | GO:0019530 | taurine metabolic process(GO:0019530) |
0.0 | 0.4 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
0.0 | 0.0 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.0 | 0.3 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
0.0 | 0.3 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
0.0 | 0.1 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.2 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
0.0 | 0.1 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
0.0 | 0.1 | GO:0044241 | lipid digestion(GO:0044241) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.6 | 2.8 | GO:0031523 | Myb complex(GO:0031523) |
0.4 | 1.6 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.4 | 1.8 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.4 | 1.1 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.4 | 1.8 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.4 | 1.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.2 | 0.7 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.2 | 1.9 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 1.3 | GO:0098536 | deuterosome(GO:0098536) |
0.2 | 0.6 | GO:0032127 | dense core granule membrane(GO:0032127) |
0.2 | 0.6 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.2 | 1.1 | GO:0035976 | AP1 complex(GO:0035976) |
0.2 | 4.4 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
0.2 | 1.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.2 | 2.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.2 | 0.5 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
0.1 | 1.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.1 | 0.5 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
0.1 | 0.5 | GO:0043293 | apoptosome(GO:0043293) |
0.1 | 1.0 | GO:0001520 | outer dense fiber(GO:0001520) |
0.1 | 0.5 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.1 | 0.3 | GO:0031251 | PAN complex(GO:0031251) |
0.1 | 1.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 4.6 | GO:0002102 | podosome(GO:0002102) |
0.1 | 0.4 | GO:0070552 | BRISC complex(GO:0070552) |
0.1 | 1.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.1 | 0.3 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.1 | 0.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 0.5 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.1 | 0.4 | GO:0035339 | SPOTS complex(GO:0035339) |
0.1 | 1.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.1 | 0.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 0.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.5 | GO:0070522 | ERCC4-ERCC1 complex(GO:0070522) |
0.1 | 0.6 | GO:0042587 | glycogen granule(GO:0042587) |
0.1 | 0.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.1 | 0.1 | GO:0000125 | PCAF complex(GO:0000125) |
0.1 | 0.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.1 | 0.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.1 | 0.5 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 0.6 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.1 | 1.8 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 0.8 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 0.2 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
0.0 | 0.3 | GO:0042825 | TAP complex(GO:0042825) |
0.0 | 0.9 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.3 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.0 | 0.2 | GO:1990246 | uniplex complex(GO:1990246) |
0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.4 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 2.1 | GO:0043034 | costamere(GO:0043034) |
0.0 | 1.2 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.8 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 2.4 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 5.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 1.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.3 | GO:0097422 | tubular endosome(GO:0097422) |
0.0 | 1.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 2.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.5 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.1 | GO:0042827 | platelet dense granule(GO:0042827) |
0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 0.6 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 2.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.1 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.0 | 0.5 | GO:0005685 | U1 snRNP(GO:0005685) |
0.0 | 0.5 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 0.1 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.0 | 0.1 | GO:0044305 | calyx of Held(GO:0044305) |
0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
0.0 | 0.3 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
0.0 | 0.3 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.1 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.0 | 2.3 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
0.0 | 2.9 | GO:0043296 | apical junction complex(GO:0043296) |
0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 1.4 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.8 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 1.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.3 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.3 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
0.0 | 1.6 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
0.0 | 0.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 0.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 0.1 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 0.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.8 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.8 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.0 | 5.9 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.7 | 2.8 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
0.5 | 1.9 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.5 | 1.8 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.3 | 3.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.3 | 3.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.3 | 1.3 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
0.3 | 1.9 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.3 | 0.9 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
0.2 | 3.0 | GO:0031996 | thioesterase binding(GO:0031996) |
0.2 | 0.7 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.2 | 2.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.2 | 1.2 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.2 | 1.1 | GO:0035240 | dopamine binding(GO:0035240) |
0.2 | 0.9 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.2 | 1.0 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.2 | 0.7 | GO:1990254 | keratin filament binding(GO:1990254) |
0.2 | 1.6 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
0.2 | 0.7 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
0.2 | 0.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.1 | 1.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 0.9 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
0.1 | 0.4 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
0.1 | 0.6 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.1 | 0.4 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.1 | 1.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 1.5 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.1 | 0.6 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.5 | GO:0050436 | microfibril binding(GO:0050436) |
0.1 | 0.5 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.1 | 1.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 1.0 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.1 | 0.4 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.1 | 1.7 | GO:0046977 | TAP binding(GO:0046977) |
0.1 | 1.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 0.5 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.1 | 0.4 | GO:0070976 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
0.1 | 4.0 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 0.7 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.8 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.8 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
0.1 | 0.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.1 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 1.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.1 | 0.3 | GO:0097677 | STAT family protein binding(GO:0097677) |
0.1 | 0.5 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
0.1 | 0.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 3.4 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.1 | 0.3 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.1 | 0.3 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 0.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 1.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.1 | 0.3 | GO:0035877 | death effector domain binding(GO:0035877) |
0.1 | 0.3 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
0.1 | 0.3 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.1 | 0.3 | GO:0030984 | kininogen binding(GO:0030984) |
0.1 | 0.3 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.1 | 0.5 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.1 | 0.4 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.1 | 1.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.1 | 1.2 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.1 | 0.4 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.3 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
0.1 | 0.2 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.1 | 0.2 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.1 | 0.3 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 6.6 | GO:0005178 | integrin binding(GO:0005178) |
0.1 | 0.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.1 | 0.2 | GO:0050632 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
0.1 | 0.3 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.1 | 0.3 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.1 | 0.4 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.7 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
0.0 | 0.6 | GO:0052744 | phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744) |
0.0 | 1.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.1 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
0.0 | 0.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.3 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.1 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.0 | 0.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 1.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 0.2 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.0 | 0.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 1.9 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.7 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.1 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.0 | 0.0 | GO:0051425 | PTB domain binding(GO:0051425) |
0.0 | 0.1 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.0 | 0.6 | GO:0030957 | Tat protein binding(GO:0030957) |
0.0 | 0.6 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.3 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 0.1 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.0 | 0.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.4 | GO:0031386 | protein tag(GO:0031386) |
0.0 | 0.5 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
0.0 | 0.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 1.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.2 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 1.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.2 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 0.3 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.1 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.0 | 0.4 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 0.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.0 | 0.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.0 | 4.1 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.7 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.2 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.1 | GO:0000405 | bubble DNA binding(GO:0000405) |
0.0 | 0.3 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
0.0 | 0.0 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.0 | 0.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 1.2 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 1.7 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.8 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.2 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
0.0 | 1.0 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.6 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.8 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 0.8 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.1 | GO:0050733 | RS domain binding(GO:0050733) |
0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.1 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.0 | 0.0 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.0 | 0.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.0 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.0 | 0.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.0 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.4 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.0 | 1.4 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
0.0 | 0.4 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
0.0 | 0.1 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.0 | 0.2 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 0.6 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.1 | 3.1 | PID_IL23_PATHWAY | IL23-mediated signaling events |
0.1 | 2.6 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.1 | 6.6 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.1 | 6.4 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.1 | 4.1 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.1 | 5.1 | PID_FGF_PATHWAY | FGF signaling pathway |
0.1 | 1.9 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.1 | 3.7 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.1 | 3.1 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.1 | 0.6 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.1 | 1.5 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 2.5 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.1 | 1.1 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
0.0 | 0.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 3.8 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 1.3 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.0 | 1.8 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 0.4 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 3.8 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 1.8 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 2.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 1.1 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 1.6 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.0 | 0.6 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.7 | PID_P73PATHWAY | p73 transcription factor network |
0.0 | 1.3 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.7 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.7 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.2 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 1.2 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 0.3 | PID_IFNG_PATHWAY | IFN-gamma pathway |
0.0 | 0.8 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
0.0 | 1.1 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.3 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 1.4 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.4 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.2 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 5.9 | REACTOME_SIGNALING_BY_FGFR3_MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.2 | 3.1 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
0.2 | 0.9 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.2 | 1.1 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.1 | 0.7 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.1 | 0.1 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
0.1 | 2.0 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.1 | 5.4 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 1.1 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 0.3 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.1 | 1.7 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.1 | 1.1 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.1 | 1.1 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.1 | 1.0 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.1 | 1.8 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.1 | 0.7 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
0.1 | 1.3 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.1 | 1.8 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.1 | 1.9 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.1 | 0.7 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.1 | 0.8 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 1.0 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 1.6 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.0 | 0.5 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
0.0 | 1.2 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.0 | 1.2 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.0 | 0.7 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
0.0 | 3.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.6 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 0.4 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.0 | 0.6 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.3 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.0 | 0.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 0.3 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 0.4 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.2 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.0 | 0.8 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.8 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 0.5 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.8 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.6 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.9 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.4 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 1.2 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.5 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.5 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.0 | 0.5 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 0.4 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.2 | REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM | Genes involved in Bile acid and bile salt metabolism |
0.0 | 0.6 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.4 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.0 | 1.3 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.8 | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
0.0 | 0.2 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 0.5 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 0.5 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 0.5 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.0 | 1.6 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.9 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |