Motif ID: Egr1

Z-value: 3.182


Transcription factors associated with Egr1:

Gene SymbolEntrez IDGene Name
Egr1 ENSMUSG00000038418.7 Egr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Egr1mm10_v2_chr18_+_34861200_348612150.214.1e-01Click!


Activity profile for motif Egr1.

activity profile for motif Egr1


Sorted Z-values histogram for motif Egr1

Sorted Z-values for motif Egr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Egr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_6065538 26.373 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr4_-_22488296 10.233 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr5_-_139130159 10.232 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_-_139129662 9.919 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr14_-_33447142 9.259 ENSMUST00000111944.3
ENSMUST00000022504.5
ENSMUST00000111945.2
Mapk8


mitogen-activated protein kinase 8


chr3_+_54156039 9.089 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr11_-_67922136 9.022 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr14_-_102982630 8.926 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr11_-_6065737 8.677 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr4_+_127169131 8.405 ENSMUST00000046659.7
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr7_+_73740277 8.282 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr14_-_30353468 7.632 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr11_+_98348404 7.284 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_27396542 6.846 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr6_-_126645784 6.680 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr7_-_45370559 6.040 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr9_+_59750876 5.922 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr5_+_137553517 5.906 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr1_-_56969864 5.904 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_28263205 5.864 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr7_+_82174796 5.536 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr7_+_82175156 5.521 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr16_+_20589471 5.457 ENSMUST00000100074.3
ENSMUST00000096197.4
Vwa5b2

von Willebrand factor A domain containing 5B2

chr1_-_189343704 5.433 ENSMUST00000180044.1
ENSMUST00000110920.1
Kcnk2

potassium channel, subfamily K, member 2

chr2_-_24763047 5.385 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr1_-_56969827 5.330 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr5_+_32136458 5.272 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chrX_-_20920911 5.126 ENSMUST00000081893.6
ENSMUST00000115345.1
Syn1

synapsin I

chr4_+_42917234 5.081 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr11_-_98053415 5.008 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr5_+_137288273 4.975 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr5_-_62766153 4.906 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_-_127666673 4.832 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr2_-_36105271 4.790 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr17_+_86167777 4.511 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr10_-_127666598 4.487 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr11_+_119942763 4.483 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr17_-_83631892 4.441 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr3_+_28263563 4.426 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr11_-_101785252 4.413 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr18_+_32163073 4.405 ENSMUST00000096575.3
Map3k2
mitogen-activated protein kinase kinase kinase 2
chr11_-_108343917 4.322 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr1_-_189343342 4.306 ENSMUST00000079451.6
Kcnk2
potassium channel, subfamily K, member 2
chr4_+_124657646 4.288 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr3_-_89089955 4.259 ENSMUST00000166687.1
Rusc1
RUN and SH3 domain containing 1
chr19_-_4698315 4.224 ENSMUST00000096325.3
Gm960
predicted gene 960
chr5_+_137030275 4.117 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr17_+_26715644 4.073 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr11_+_85832551 4.050 ENSMUST00000000095.6
Tbx2
T-box 2
chr7_-_47132698 4.018 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr8_+_104170513 4.012 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr11_-_37235882 3.876 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr2_-_25319095 3.764 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr9_-_56418023 3.761 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr10_+_79716588 3.689 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr10_-_116473418 3.678 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr9_+_60712989 3.645 ENSMUST00000038407.5
Larp6
La ribonucleoprotein domain family, member 6
chr7_+_5056856 3.591 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr4_-_149774238 3.566 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr9_-_107710475 3.547 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chrX_-_73660047 3.541 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr10_-_54075730 3.453 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr10_-_80139347 3.440 ENSMUST00000105369.1
Dos
downstream of Stk11
chr11_+_42419729 3.434 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr13_-_107890059 3.427 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr12_+_36157124 3.411 ENSMUST00000041640.3
Ankmy2
ankyrin repeat and MYND domain containing 2
chr3_+_117575268 3.326 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr4_-_151861762 3.276 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr14_-_76556662 3.265 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr12_-_76709997 3.260 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr8_+_95678085 3.260 ENSMUST00000041318.7
Ndrg4
N-myc downstream regulated gene 4
chr1_-_22805994 3.258 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr16_+_44173271 3.208 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr2_-_168741898 3.195 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr7_+_122671378 3.179 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr2_-_136387929 3.173 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr7_+_122671401 3.131 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr10_-_81472859 3.128 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chr3_-_86920830 3.115 ENSMUST00000029719.8
Dclk2
doublecortin-like kinase 2
chr4_+_42949814 3.112 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr11_+_97415527 3.091 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr9_-_24503127 3.089 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr4_+_136286061 3.085 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr12_+_78226627 3.075 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn

gephyrin

chr14_-_55585250 3.029 ENSMUST00000022828.8
Emc9
ER membrane protein complex subunit 9
chr15_+_89499598 2.971 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr16_-_18629864 2.946 ENSMUST00000096987.5
Sept5
septin 5
chr19_+_27217357 2.944 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr1_+_75382114 2.939 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr7_+_5057161 2.926 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr16_+_94370786 2.905 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr6_-_85502980 2.901 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr2_-_32312162 2.896 ENSMUST00000155269.1
Dnm1
dynamin 1
chr9_-_112187898 2.886 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr6_-_85502858 2.879 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr7_+_99535652 2.850 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr2_+_157914618 2.842 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr9_-_112187766 2.824 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr10_-_116473875 2.775 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_-_84800024 2.752 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr4_+_138250403 2.747 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr9_-_51008936 2.734 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr12_+_102949450 2.728 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr4_-_151861698 2.711 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chrX_-_47892502 2.699 ENSMUST00000077569.4
ENSMUST00000101616.2
ENSMUST00000088973.4
Smarca1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr19_+_6399857 2.691 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr2_+_145167706 2.689 ENSMUST00000110007.1
Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr15_-_76660108 2.681 ENSMUST00000066677.8
ENSMUST00000177359.1
Cyhr1

cysteine and histidine rich 1

chr14_-_20546512 2.663 ENSMUST00000022355.4
ENSMUST00000161445.1
ENSMUST00000159027.1
Ppp3cb


protein phosphatase 3, catalytic subunit, beta isoform


chr19_-_50678642 2.661 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chrX_-_160994665 2.660 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chrX_-_47892396 2.640 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr8_-_73353477 2.636 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr9_-_107231816 2.635 ENSMUST00000044532.4
Dock3
dedicator of cyto-kinesis 3
chr16_+_94370618 2.613 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr11_-_97573929 2.594 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1

SRC kinase signaling inhibitor 1

chrY_+_897782 2.554 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr16_+_20696175 2.513 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr16_+_10545339 2.505 ENSMUST00000066345.7
ENSMUST00000115824.3
ENSMUST00000155633.1
Clec16a


C-type lectin domain family 16, member A


chr4_-_126753372 2.503 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr9_-_54501496 2.493 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr9_+_21032038 2.482 ENSMUST00000019616.4
Icam5
intercellular adhesion molecule 5, telencephalin
chr11_-_97574040 2.481 ENSMUST00000107593.1
Srcin1
SRC kinase signaling inhibitor 1
chr16_+_44173239 2.476 ENSMUST00000119746.1
Gm608
predicted gene 608
chr7_-_45366714 2.466 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr12_+_102948843 2.447 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chrX_-_47892432 2.447 ENSMUST00000141084.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr3_+_96596628 2.445 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr19_+_27217011 2.443 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr7_+_5056706 2.437 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr13_-_54749627 2.430 ENSMUST00000099506.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr19_+_37550397 2.407 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr4_-_40722307 2.395 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr11_+_75193783 2.394 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr14_-_60177482 2.383 ENSMUST00000140924.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr8_-_70234401 2.345 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr15_+_99295087 2.329 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr10_-_54075702 2.328 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr17_+_26414820 2.302 ENSMUST00000182897.1
ENSMUST00000183077.1
ENSMUST00000053020.7
Neurl1b


neuralized homolog 1b (Drosophila)


chr11_+_54522872 2.299 ENSMUST00000108895.1
ENSMUST00000101206.3
Rapgef6

Rap guanine nucleotide exchange factor (GEF) 6

chr16_-_4880284 2.291 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr2_-_181135220 2.290 ENSMUST00000016491.7
Kcnq2
potassium voltage-gated channel, subfamily Q, member 2
chr2_+_118111876 2.272 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr3_+_136670679 2.268 ENSMUST00000056758.8
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr4_+_43046014 2.267 ENSMUST00000180426.1
Gm26881
predicted gene, 26881
chr1_-_52233211 2.251 ENSMUST00000114513.2
ENSMUST00000114510.1
Gls

glutaminase

chr14_-_105896819 2.243 ENSMUST00000022709.4
Spry2
sprouty homolog 2 (Drosophila)
chr8_-_64205970 2.238 ENSMUST00000066166.4
Tll1
tolloid-like
chr19_-_5098418 2.217 ENSMUST00000025805.6
Cnih2
cornichon homolog 2 (Drosophila)
chr4_-_148287927 2.213 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr6_-_60828889 2.168 ENSMUST00000114268.3
Snca
synuclein, alpha
chr10_+_83543941 2.155 ENSMUST00000038388.5
A230046K03Rik
RIKEN cDNA A230046K03 gene
chrX_+_152144240 2.144 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chr8_-_70234097 2.136 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chrX_+_23693043 2.130 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chr16_-_20621255 2.129 ENSMUST00000052939.2
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr12_+_71309876 2.117 ENSMUST00000061273.5
ENSMUST00000150639.1
Dact1

dapper homolog 1, antagonist of beta-catenin (xenopus)

chr18_+_64887690 2.099 ENSMUST00000163516.1
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr8_+_88697022 2.095 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr2_-_161109017 2.081 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr7_+_80860909 2.078 ENSMUST00000132163.1
ENSMUST00000147125.1
Zscan2

zinc finger and SCAN domain containing 2

chr14_-_52279238 2.068 ENSMUST00000167116.1
ENSMUST00000100631.4
Rab2b

RAB2B, member RAS oncogene family

chr11_+_54522847 2.056 ENSMUST00000102743.3
Rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr10_+_98915117 2.044 ENSMUST00000020107.7
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr4_-_41774097 2.040 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
Ccl27a



chemokine (C-C motif) ligand 27A



chr7_+_126950837 2.019 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr16_+_10545390 2.018 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr2_-_25319187 1.983 ENSMUST00000114312.1
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr6_+_121636173 1.973 ENSMUST00000032203.7
A2m
alpha-2-macroglobulin
chr7_-_16286744 1.957 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr8_+_84415348 1.947 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr3_+_106721893 1.938 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
Lrif1



ligand dependent nuclear receptor interacting factor 1



chr1_-_52232296 1.910 ENSMUST00000114512.1
Gls
glutaminase
chr12_+_5375870 1.909 ENSMUST00000037953.6
2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr6_-_4747019 1.907 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
Sgce


sarcoglycan, epsilon


chr4_+_42154040 1.904 ENSMUST00000108018.2
Gm13306
predicted gene 13306
chr13_-_96132568 1.894 ENSMUST00000161263.1
Sv2c
synaptic vesicle glycoprotein 2c
chr3_+_106721672 1.877 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chr11_-_78497458 1.868 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr11_+_51263114 1.863 ENSMUST00000093132.6
ENSMUST00000109113.1
Clk4

CDC like kinase 4

chrX_-_20291776 1.862 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr2_+_156613664 1.858 ENSMUST00000169464.2
ENSMUST00000109567.3
Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chrX_-_73659724 1.857 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr5_-_77408034 1.855 ENSMUST00000163898.1
ENSMUST00000046746.6
Igfbp7

insulin-like growth factor binding protein 7

chr2_+_52857844 1.853 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
Fmnl2


formin-like 2


chr7_+_120843551 1.841 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr19_+_42255704 1.834 ENSMUST00000087123.5
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr14_+_101653967 1.828 ENSMUST00000002289.6
Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr13_-_43304153 1.821 ENSMUST00000055341.5
Gfod1
glucose-fructose oxidoreductase domain containing 1
chr3_-_89093358 1.776 ENSMUST00000090929.5
ENSMUST00000052539.6
Rusc1

RUN and SH3 domain containing 1

chr9_-_119093468 1.773 ENSMUST00000010804.2
Plcd1
phospholipase C, delta 1
chr15_-_45114926 1.764 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr2_-_165473187 1.759 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr7_+_101108768 1.753 ENSMUST00000098250.3
ENSMUST00000032931.7
Fchsd2

FCH and double SH3 domains 2

chr2_-_167188787 1.737 ENSMUST00000059826.8
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr7_-_97332017 1.716 ENSMUST00000139582.2
Usp35
ubiquitin specific peptidase 35
chr9_+_58582397 1.706 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr7_+_130936172 1.678 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chrX_+_6047453 1.676 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr5_+_100039990 1.673 ENSMUST00000169390.1
ENSMUST00000031268.6
Enoph1

enolase-phosphatase 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.0 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
3.2 9.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
2.4 7.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
2.3 9.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
2.2 6.7 GO:0050975 sensory perception of touch(GO:0050975)
2.2 11.1 GO:0007256 activation of JNKK activity(GO:0007256)
1.9 5.7 GO:1900673 olefin metabolic process(GO:1900673)
1.7 20.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4 4.3 GO:0002159 desmosome assembly(GO:0002159)
1.3 4.0 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
1.3 9.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
1.2 6.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.1 6.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.1 4.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.1 1.1 GO:0060667 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
1.1 5.4 GO:0034436 glycoprotein transport(GO:0034436)
1.1 4.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
1.0 3.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.0 1.9 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.9 4.7 GO:2001025 positive regulation of response to drug(GO:2001025)
0.9 12.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.9 4.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.9 7.2 GO:0005513 detection of calcium ion(GO:0005513)
0.9 3.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.8 4.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.8 5.0 GO:0019695 choline metabolic process(GO:0019695)
0.8 3.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.8 4.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.8 3.9 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.8 2.3 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752)
0.8 2.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.7 11.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.7 1.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.7 3.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.7 3.7 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.7 4.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.7 9.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.7 1.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.7 3.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.7 4.1 GO:0032796 uropod organization(GO:0032796)
0.7 2.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.7 2.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.6 2.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 3.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.6 3.0 GO:0090292 nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.6 3.5 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.6 2.9 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.6 2.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.6 5.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.6 2.2 GO:0060437 lung growth(GO:0060437)
0.5 2.2 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) regulation of peroxidase activity(GO:2000468)
0.5 10.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.5 2.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.5 1.6 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.5 2.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 7.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.5 3.9 GO:0097264 self proteolysis(GO:0097264)
0.5 1.4 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.5 1.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 1.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 7.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.4 2.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.4 2.1 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.4 1.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 5.4 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.4 4.1 GO:0043084 penile erection(GO:0043084)
0.4 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.4 0.8 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.4 1.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 3.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 3.4 GO:0071420 cellular response to histamine(GO:0071420)
0.4 1.1 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881) positive regulation of ovulation(GO:0060279)
0.4 7.8 GO:0006491 N-glycan processing(GO:0006491)
0.4 3.0 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4 2.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.3 3.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 2.4 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 1.7 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 1.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 6.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 1.5 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 3.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 0.9 GO:0030070 insulin processing(GO:0030070)
0.3 1.2 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.3 1.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.3 1.5 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 4.1 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response(GO:1900102)
0.3 0.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 1.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.3 1.7 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 1.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 2.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 4.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 0.8 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.3 3.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 1.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.2 3.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 0.5 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 2.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.2 0.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.2 1.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 1.6 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 4.4 GO:0030033 microvillus assembly(GO:0030033)
0.2 1.1 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 2.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 2.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 3.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 7.9 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 2.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.2 1.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 1.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 2.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 0.6 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.2 1.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 4.9 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 0.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.2 2.9 GO:0001914 regulation of T cell mediated cytotoxicity(GO:0001914)
0.2 2.5 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2 1.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 3.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 1.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 3.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.0 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 1.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 3.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 5.3 GO:0032355 response to estradiol(GO:0032355)
0.1 0.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.7 GO:0030578 PML body organization(GO:0030578)
0.1 0.6 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.6 GO:0009408 response to heat(GO:0009408)
0.1 0.9 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 3.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.2 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 3.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 5.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 2.0 GO:0060074 synapse maturation(GO:0060074)
0.1 1.3 GO:0016926 protein desumoylation(GO:0016926)
0.1 3.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.4 GO:0051693 actin filament capping(GO:0051693)
0.1 1.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 3.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.5 GO:0032026 response to magnesium ion(GO:0032026)
0.1 0.6 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.5 GO:0009615 response to virus(GO:0009615)
0.1 9.8 GO:0016579 protein deubiquitination(GO:0016579)
0.1 3.3 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.1 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 5.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 3.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.7 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 1.4 GO:0001706 endoderm formation(GO:0001706)
0.1 2.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.6 GO:0061157 mRNA destabilization(GO:0061157)
0.1 2.9 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 1.8 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 0.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 1.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 8.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.9 GO:0044804 nucleophagy(GO:0044804)
0.0 0.6 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.2 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.9 GO:0006298 mismatch repair(GO:0006298)
0.0 2.2 GO:1900076 regulation of cellular response to insulin stimulus(GO:1900076)
0.0 1.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 4.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 2.6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.7 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.4 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 1.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 3.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 3.3 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 1.9 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.6 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 1.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.0 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.8 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0090537 CERF complex(GO:0090537)
1.7 10.1 GO:0008091 spectrin(GO:0008091)
1.6 9.7 GO:0044305 calyx of Held(GO:0044305)
1.5 20.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.4 5.7 GO:0044307 dendritic branch(GO:0044307)
1.2 3.7 GO:0098855 HCN channel complex(GO:0098855)
1.1 6.3 GO:0005955 calcineurin complex(GO:0005955)
1.0 33.9 GO:0051233 spindle midzone(GO:0051233)
0.9 2.7 GO:1990075 periciliary membrane compartment(GO:1990075)
0.9 6.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.8 3.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.8 3.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.8 7.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.8 2.3 GO:0005577 fibrinogen complex(GO:0005577)
0.6 1.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.6 8.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.5 1.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.5 7.9 GO:1990635 proximal dendrite(GO:1990635)
0.5 5.0 GO:0043083 synaptic cleft(GO:0043083)
0.4 5.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.4 4.1 GO:0032426 stereocilium tip(GO:0032426)
0.4 3.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4 10.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 3.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 17.5 GO:0034704 calcium channel complex(GO:0034704)
0.4 6.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 2.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 1.1 GO:0043511 inhibin complex(GO:0043511)
0.3 8.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 0.8 GO:0044194 cytolytic granule(GO:0044194)
0.3 17.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 2.4 GO:0071141 SMAD protein complex(GO:0071141)
0.2 3.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.1 GO:1902710 GABA receptor complex(GO:1902710)
0.2 2.8 GO:0031143 pseudopodium(GO:0031143)
0.2 5.1 GO:0071565 nBAF complex(GO:0071565)
0.2 8.1 GO:0048786 presynaptic active zone(GO:0048786)
0.2 2.9 GO:0031105 septin complex(GO:0031105)
0.2 2.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.7 GO:0043293 apoptosome(GO:0043293)
0.2 2.1 GO:0097542 ciliary tip(GO:0097542)
0.2 3.1 GO:0060077 inhibitory synapse(GO:0060077)
0.2 1.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 5.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.1 GO:0098830 presynaptic endosome(GO:0098830)
0.1 2.4 GO:0000145 exocyst(GO:0000145)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 1.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.9 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.6 GO:0032433 filopodium tip(GO:0032433)
0.1 12.0 GO:0055037 recycling endosome(GO:0055037)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 1.1 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.5 GO:0031430 M band(GO:0031430)
0.1 3.1 GO:0032420 stereocilium(GO:0032420)
0.1 4.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 3.6 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.6 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 17.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.2 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 3.7 GO:0016459 myosin complex(GO:0016459)
0.1 2.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.8 GO:0097060 synaptic membrane(GO:0097060)
0.1 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 4.5 GO:0010008 endosome membrane(GO:0010008)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 7.1 GO:0005769 early endosome(GO:0005769)
0.0 10.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 2.9 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0030426 growth cone(GO:0030426)
0.0 5.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
2.4 7.3 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
2.3 9.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.8 20.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.8 5.4 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
1.4 4.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.4 36.7 GO:0043274 phospholipase binding(GO:0043274)
1.2 5.0 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
1.2 11.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.1 15.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.1 4.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.0 6.0 GO:0097016 L27 domain binding(GO:0097016)
1.0 5.7 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.9 2.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 3.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.9 3.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.9 5.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 3.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8 10.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.8 4.2 GO:0004359 glutaminase activity(GO:0004359)
0.8 2.4 GO:0035500 MH2 domain binding(GO:0035500)
0.8 3.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.8 2.3 GO:0070052 collagen V binding(GO:0070052)
0.7 3.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.7 12.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 7.8 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.7 9.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 2.0 GO:0019966 C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
0.6 1.8 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.6 1.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.6 1.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.6 4.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 2.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 1.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 1.4 GO:0019002 GMP binding(GO:0019002)
0.4 2.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.4 6.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 3.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.4 4.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 1.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 2.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 2.9 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.4 2.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3 1.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.3 1.2 GO:2001069 glycogen binding(GO:2001069)
0.3 1.7 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.3 1.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 3.5 GO:0038191 neuropilin binding(GO:0038191)
0.3 3.0 GO:0043495 protein anchor(GO:0043495)
0.3 2.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 1.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.5 GO:0097001 ceramide binding(GO:0097001)
0.2 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 6.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 6.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 1.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 5.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 0.7 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 4.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 2.1 GO:0070097 delta-catenin binding(GO:0070097)
0.2 4.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 6.8 GO:0071837 HMG box domain binding(GO:0071837)
0.2 0.8 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 1.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 4.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 2.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 3.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 6.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 3.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 6.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.1 GO:0034711 inhibin binding(GO:0034711)
0.1 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 11.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 5.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 4.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.9 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 3.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 5.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 6.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.3 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.5 GO:0030552 cAMP binding(GO:0030552)
0.1 3.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.0 GO:0030332 cyclin binding(GO:0030332)
0.1 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 5.9 GO:0003774 motor activity(GO:0003774)
0.0 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 3.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 6.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 2.5 GO:0004620 phospholipase activity(GO:0004620)
0.0 7.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 5.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017) nucleoside kinase activity(GO:0019206)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 4.7 GO:0045296 cadherin binding(GO:0045296)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.6 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 33.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.6 8.8 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 22.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.4 0.9 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 13.7 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 7.8 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 5.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 4.8 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 9.7 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 6.3 PID_ARF6_PATHWAY Arf6 signaling events
0.2 9.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.2 2.1 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 5.7 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.2 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 2.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 4.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 8.3 PID_LKB1_PATHWAY LKB1 signaling events
0.1 4.7 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 2.2 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 1.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 2.4 PID_INSULIN_PATHWAY Insulin Pathway
0.1 0.6 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 1.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.1 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 0.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 4.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.9 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.7 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.2 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.9 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 40.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
1.6 11.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.9 20.5 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.8 9.1 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.7 8.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.7 9.8 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.5 4.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 12.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.4 17.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.4 3.8 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.4 4.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 8.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.3 1.1 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.3 2.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.3 2.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.2 3.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 3.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 5.0 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.2 2.0 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 1.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.9 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.8 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 5.5 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 6.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 3.1 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 3.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 4.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 10.4 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 5.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 0.8 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 0.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.7 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.4 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 1.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 7.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.5 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.1 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 1.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 9.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 2.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates