Motif ID: Etv4

Z-value: 0.630


Transcription factors associated with Etv4:

Gene SymbolEntrez IDGene Name
Etv4 ENSMUSG00000017724.8 Etv4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv4mm10_v2_chr11_-_101785252_101785371-0.038.9e-01Click!


Activity profile for motif Etv4.

activity profile for motif Etv4


Sorted Z-values histogram for motif Etv4

Sorted Z-values for motif Etv4



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_56133817 1.286 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr6_+_5725639 1.085 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr15_-_66969616 1.011 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr15_-_66812593 0.951 ENSMUST00000100572.3
Sla
src-like adaptor
chr13_+_109632760 0.951 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr11_-_76509419 0.902 ENSMUST00000094012.4
Abr
active BCR-related gene
chr7_+_45627482 0.811 ENSMUST00000057927.7
Rasip1
Ras interacting protein 1
chr17_+_3397189 0.783 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr6_+_8259288 0.722 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr9_-_29411736 0.704 ENSMUST00000115236.1
Ntm
neurotrimin
chr11_-_45944910 0.679 ENSMUST00000129820.1
Lsm11
U7 snRNP-specific Sm-like protein LSM11
chr9_+_107935876 0.632 ENSMUST00000035700.8
Camkv
CaM kinase-like vesicle-associated
chr13_+_83504032 0.594 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr13_-_49309217 0.564 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr5_+_117133567 0.541 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr6_+_8259327 0.539 ENSMUST00000159378.1
Gm16039
predicted gene 16039
chr5_-_103100054 0.518 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr3_+_123267445 0.517 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr13_+_109260481 0.512 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr12_-_84970814 0.511 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
Arel1


apoptosis resistant E3 ubiquitin protein ligase 1


chr18_+_23803962 0.508 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr9_+_108290433 0.487 ENSMUST00000035227.6
Nicn1
nicolin 1
chr11_+_103171081 0.486 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr7_+_49246131 0.473 ENSMUST00000064395.6
Nav2
neuron navigator 2
chrX_+_159840463 0.467 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr2_-_5714490 0.454 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr6_+_55836878 0.453 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr9_-_110476637 0.453 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr2_+_70563435 0.451 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr6_+_8259379 0.443 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr13_+_119623819 0.439 ENSMUST00000099241.2
Ccl28
chemokine (C-C motif) ligand 28
chr9_-_29412204 0.437 ENSMUST00000115237.1
Ntm
neurotrimin
chr14_-_76556662 0.437 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr11_+_83302641 0.436 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr1_-_56969864 0.426 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr17_-_80290476 0.424 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr14_+_80000292 0.422 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr8_+_70501116 0.414 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr17_-_50094277 0.407 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr1_-_124045523 0.396 ENSMUST00000112606.1
Dpp10
dipeptidylpeptidase 10
chr14_-_19977249 0.390 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_87592145 0.388 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr1_-_124045247 0.382 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chr5_+_122391878 0.379 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr4_-_127313980 0.377 ENSMUST00000053753.7
Gja4
gap junction protein, alpha 4
chr14_-_19977040 0.375 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_83302817 0.369 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr3_-_104511812 0.368 ENSMUST00000046316.6
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr14_-_19977151 0.367 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr2_+_168230597 0.366 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr6_+_86849488 0.360 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr4_+_43562672 0.360 ENSMUST00000167751.1
ENSMUST00000132631.1
Creb3

cAMP responsive element binding protein 3

chr15_-_100403243 0.356 ENSMUST00000124324.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr15_+_98167806 0.344 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr16_+_29579347 0.340 ENSMUST00000038867.6
ENSMUST00000161186.1
Opa1

optic atrophy 1

chr9_+_58582240 0.333 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr17_+_35135196 0.333 ENSMUST00000172571.1
ENSMUST00000173491.1
Bag6

BCL2-associated athanogene 6

chr16_-_94526830 0.332 ENSMUST00000023615.6
Dscr3
Down syndrome critical region gene 3
chr3_-_87768932 0.328 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr15_-_79804717 0.327 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr1_-_56969827 0.326 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr7_+_29309429 0.326 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr3_+_82358056 0.326 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr1_-_191318090 0.326 ENSMUST00000046770.9
Nenf
neuron derived neurotrophic factor
chr18_+_37294840 0.323 ENSMUST00000056522.3
Pcdhb2
protocadherin beta 2
chr7_-_27181149 0.318 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr15_+_30172570 0.317 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr13_+_24614608 0.317 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr15_+_25984359 0.314 ENSMUST00000061875.6
Zfp622
zinc finger protein 622
chr9_+_56418624 0.314 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr15_-_98567630 0.312 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr18_+_37473538 0.304 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr11_+_73177236 0.304 ENSMUST00000108477.1
Tax1bp3
Tax1 (human T cell leukemia virus type I) binding protein 3
chr2_+_91650169 0.301 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr4_-_118489755 0.300 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr11_-_105944412 0.300 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
Cyb561


cytochrome b-561


chr1_+_118389058 0.295 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
Clasp1



CLIP associating protein 1



chr4_-_122885965 0.289 ENSMUST00000128485.1
Cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_52817643 0.288 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr4_+_103313806 0.287 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr2_+_91650116 0.287 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr3_-_127409014 0.286 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr17_+_35135174 0.286 ENSMUST00000166426.2
ENSMUST00000025250.7
Bag6

BCL2-associated athanogene 6

chr11_+_101245996 0.283 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr16_-_35769356 0.280 ENSMUST00000023554.8
Dirc2
disrupted in renal carcinoma 2 (human)
chr1_-_52817503 0.280 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr7_+_122067164 0.277 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr5_-_118244861 0.277 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr16_+_29579331 0.275 ENSMUST00000160597.1
Opa1
optic atrophy 1
chr3_+_98382438 0.274 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr19_-_6235804 0.273 ENSMUST00000025695.9
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr7_+_97081711 0.273 ENSMUST00000004622.5
Gab2
growth factor receptor bound protein 2-associated protein 2
chr3_+_98382538 0.270 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr8_-_105295934 0.269 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr2_-_12419387 0.263 ENSMUST00000124515.1
Fam188a
family with sequence similarity 188, member A
chr3_-_127408937 0.260 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr5_+_34543365 0.259 ENSMUST00000101316.3
Sh3bp2
SH3-domain binding protein 2
chr12_-_4038905 0.259 ENSMUST00000111178.1
Efr3b
EFR3 homolog B (S. cerevisiae)
chr11_-_87826023 0.255 ENSMUST00000103177.3
Lpo
lactoperoxidase
chr12_-_67221221 0.254 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr5_+_75574916 0.251 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr17_+_8311101 0.251 ENSMUST00000154553.1
Sft2d1
SFT2 domain containing 1
chr1_-_54926311 0.249 ENSMUST00000179030.1
ENSMUST00000044359.9
Ankrd44

ankyrin repeat domain 44

chr2_-_23040092 0.248 ENSMUST00000153931.1
ENSMUST00000123948.1
Abi1

abl-interactor 1

chr12_-_87266227 0.247 ENSMUST00000072744.7
ENSMUST00000179379.1
Vipas39

VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog

chr19_-_57360668 0.245 ENSMUST00000181921.1
B230217O12Rik
RIKEN cDNA B230217O12 gene
chr11_+_77765588 0.242 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr5_-_3803081 0.241 ENSMUST00000043551.6
Ankib1
ankyrin repeat and IBR domain containing 1
chr9_+_32224457 0.241 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr5_+_117363513 0.240 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr11_+_83299005 0.240 ENSMUST00000176944.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr11_-_20112876 0.238 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr1_-_183297008 0.238 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr2_-_66410064 0.238 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr9_-_40346290 0.237 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr11_+_97362396 0.236 ENSMUST00000045540.3
Socs7
suppressor of cytokine signaling 7
chr19_-_40402267 0.233 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1



chr9_+_58582397 0.232 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr19_+_4231899 0.231 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr7_+_73740277 0.230 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr1_+_180726019 0.230 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr2_-_92024502 0.228 ENSMUST00000028663.4
Creb3l1
cAMP responsive element binding protein 3-like 1
chr5_-_25100624 0.228 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr4_-_135494615 0.227 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr16_-_44139630 0.225 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr2_-_120353094 0.225 ENSMUST00000028752.7
ENSMUST00000102501.3
Vps39

vacuolar protein sorting 39 (yeast)

chr3_+_28263205 0.224 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr10_-_89732253 0.223 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr4_-_122886044 0.222 ENSMUST00000106255.1
ENSMUST00000106257.3
Cap1

CAP, adenylate cyclase-associated protein 1 (yeast)

chr1_+_179546303 0.221 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr11_+_69059750 0.220 ENSMUST00000051888.2
2310047M10Rik
RIKEN cDNA 2310047M10 gene
chr14_-_74947865 0.214 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr1_-_85598796 0.213 ENSMUST00000093508.6
Sp110
Sp110 nuclear body protein
chr11_+_6200029 0.212 ENSMUST00000181545.1
A730071L15Rik
RIKEN cDNA A730071L15Rik gene
chr3_-_127409044 0.209 ENSMUST00000182704.1
Ank2
ankyrin 2, brain
chr8_+_72219726 0.209 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr15_-_28025834 0.209 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)
chr5_+_29735991 0.208 ENSMUST00000012734.5
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr8_-_71723308 0.208 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr9_+_21592722 0.206 ENSMUST00000062125.10
1810026J23Rik
RIKEN cDNA 1810026J23 gene
chr6_-_99028251 0.205 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr17_+_33955902 0.205 ENSMUST00000173196.2
Vps52
vacuolar protein sorting 52 (yeast)
chr13_+_77708683 0.205 ENSMUST00000163257.1
ENSMUST00000091459.4
ENSMUST00000099358.3
Fam172a


family with sequence similarity 172, member A


chr5_+_29735940 0.205 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr11_+_3330781 0.204 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr3_-_50443603 0.204 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr17_-_24936894 0.203 ENSMUST00000115228.2
ENSMUST00000117509.1
ENSMUST00000121723.1
ENSMUST00000119115.1
ENSMUST00000121787.1
ENSMUST00000088345.5
ENSMUST00000120035.1
Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr18_-_23038656 0.203 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr9_-_44965519 0.203 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a


ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)


chr16_-_55895279 0.199 ENSMUST00000099705.3
Nxpe3
neurexophilin and PC-esterase domain family, member 3
chr15_-_33405976 0.198 ENSMUST00000079057.6
1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr13_-_100730839 0.197 ENSMUST00000091299.6
Cdk7
cyclin-dependent kinase 7
chr7_+_129591859 0.197 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chrX_+_152178945 0.197 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chr2_-_102400863 0.197 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr10_-_84440591 0.196 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr11_+_29692937 0.195 ENSMUST00000102843.3
ENSMUST00000102842.3
ENSMUST00000078830.4
ENSMUST00000170731.1
Rtn4



reticulon 4



chr9_-_60688118 0.195 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr4_+_44012661 0.195 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr2_+_32646586 0.194 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr2_+_130405256 0.192 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr11_-_6200411 0.188 ENSMUST00000066496.3
Nudcd3
NudC domain containing 3
chr11_-_75454656 0.188 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr9_-_75683992 0.188 ENSMUST00000034699.6
Scg3
secretogranin III
chr8_+_109778554 0.188 ENSMUST00000093157.6
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr2_-_7395879 0.188 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr16_-_4880284 0.187 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr2_+_37452231 0.183 ENSMUST00000148470.1
ENSMUST00000066055.3
ENSMUST00000112920.1
Rabgap1


RAB GTPase activating protein 1


chr8_+_109778863 0.183 ENSMUST00000034171.8
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr17_+_55445550 0.182 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr3_-_89773221 0.179 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr7_+_7171330 0.178 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr2_-_23040137 0.178 ENSMUST00000091394.6
ENSMUST00000093171.6
Abi1

abl-interactor 1

chr9_+_32224246 0.177 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr5_-_92435114 0.177 ENSMUST00000135112.1
Nup54
nucleoporin 54
chrX_+_163909132 0.174 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr16_-_44139003 0.174 ENSMUST00000124102.1
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr17_+_29268788 0.174 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr1_-_125435694 0.174 ENSMUST00000178474.1
ENSMUST00000027579.10
Actr3

ARP3 actin-related protein 3

chr16_-_17405877 0.174 ENSMUST00000154364.1
Pi4ka
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
chr18_+_30272747 0.173 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
Pik3c3


phosphoinositide-3-kinase, class 3


chr2_+_147012996 0.171 ENSMUST00000028921.5
Xrn2
5'-3' exoribonuclease 2
chr17_+_37050631 0.170 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr11_+_70647258 0.169 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr2_+_4559742 0.169 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr3_-_127408986 0.168 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
Ank2


ankyrin 2, brain


chr17_-_24527830 0.165 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr6_-_8259098 0.165 ENSMUST00000012627.4
Rpa3
replication protein A3
chr5_-_135744206 0.164 ENSMUST00000153399.1
ENSMUST00000043378.2
Tmem120a

transmembrane protein 120A

chr12_-_27160311 0.164 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr17_-_24936969 0.161 ENSMUST00000178969.1
ENSMUST00000115229.3
Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

chr2_-_91183818 0.161 ENSMUST00000075269.3
ENSMUST00000111371.1
ENSMUST00000111372.1
ENSMUST00000111381.2
ENSMUST00000077941.6
ENSMUST00000066473.5
Madd





MAP-kinase activating death domain





chr8_+_85071737 0.161 ENSMUST00000078665.6
Dhps
deoxyhypusine synthase
chr7_+_80261202 0.160 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chr4_+_136462250 0.159 ENSMUST00000084593.2
6030445D17Rik
RIKEN cDNA 6030445D17 gene
chr4_+_44012638 0.159 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr11_+_54522872 0.159 ENSMUST00000108895.1
ENSMUST00000101206.3
Rapgef6

Rap guanine nucleotide exchange factor (GEF) 6

chr11_-_115276973 0.157 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr12_+_83688123 0.157 ENSMUST00000041806.5
Psen1
presenilin 1
chr1_-_121328024 0.156 ENSMUST00000003818.7
Insig2
insulin induced gene 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 0.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 0.7 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.1 0.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.5 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 0.4 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:0019046 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.1 0.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.5 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.1 0.8 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.9 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.1 1.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.3 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.3 GO:0010637 diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0015871 astrocyte activation involved in immune response(GO:0002265) choline transport(GO:0015871)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.3 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.5 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.0 GO:0051884 regulation of anagen(GO:0051884)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0021886 female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.6 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.0 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.0 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.1 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0019034 viral replication complex(GO:0019034)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0044437 vacuolar part(GO:0044437)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.1 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0052742 phosphatidylinositol kinase activity(GO:0052742)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 3.2 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.1 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.6 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 2.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.0 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.0 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.1 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation