Motif ID: Stat1

Z-value: 0.754


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_52119499-0.223.8e-01Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_80802789 3.893 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_-_64046925 2.686 ENSMUST00000107377.3
Tnc
tenascin C
chrX_-_61185558 2.578 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr12_+_74297474 1.792 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr7_+_45783686 1.395 ENSMUST00000118564.1
ENSMUST00000133428.1
Lmtk3

lemur tyrosine kinase 3

chr10_+_69925766 1.352 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr9_-_96719404 1.324 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr10_+_69925954 1.321 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr7_+_45783883 1.276 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr9_+_20868628 1.228 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr12_+_11265867 1.181 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr11_+_101245996 1.168 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr10_+_69925800 1.155 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr11_+_78499087 1.136 ENSMUST00000017488.4
Vtn
vitronectin
chrX_-_88760312 1.101 ENSMUST00000182943.1
Gm27000
predicted gene, 27000
chr1_-_155417394 1.049 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr12_+_109544498 1.048 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr13_+_109903089 1.046 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr19_-_46327121 1.013 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr2_+_3424123 0.988 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr17_-_68004075 0.982 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr7_+_24112314 0.944 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr4_-_108032069 0.934 ENSMUST00000106709.2
Podn
podocan
chr3_-_10440054 0.922 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr9_-_96719549 0.877 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr16_-_74411776 0.875 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr4_-_108031938 0.869 ENSMUST00000106708.1
Podn
podocan
chr3_+_96576984 0.860 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr16_-_20426322 0.811 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr1_-_155417283 0.794 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr2_+_178193075 0.777 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr5_-_123140135 0.762 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr9_+_44981779 0.758 ENSMUST00000034602.7
Cd3d
CD3 antigen, delta polypeptide
chrX_-_47892396 0.728 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr13_-_67755132 0.724 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr10_-_18234930 0.712 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr7_+_24134148 0.699 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr19_-_37207293 0.699 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr8_-_105326252 0.695 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr14_+_84443553 0.690 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr1_+_34005872 0.688 ENSMUST00000182296.1
Dst
dystonin
chr7_+_29768552 0.681 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr18_+_37320374 0.675 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr13_-_67755192 0.675 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr7_+_30095150 0.657 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr10_+_40349265 0.637 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr9_+_45117813 0.634 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr1_+_136624901 0.623 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr15_-_54919961 0.608 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr9_+_32224457 0.587 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr4_+_148602527 0.585 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr2_-_120970706 0.581 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr2_-_127584668 0.569 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chr10_-_127041513 0.557 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr16_-_20426375 0.554 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr5_-_34513892 0.542 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr8_-_67910911 0.532 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr16_-_20425881 0.523 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_+_43401232 0.510 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr13_-_85288999 0.508 ENSMUST00000109552.2
Rasa1
RAS p21 protein activator 1
chr15_-_37458523 0.500 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr16_-_42340595 0.464 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr1_-_64121389 0.445 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr3_+_142496924 0.437 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr7_-_105399991 0.431 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr8_-_70776650 0.430 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr11_-_101425330 0.427 ENSMUST00000103102.3
Ptges3l
prostaglandin E synthase 3 (cytosolic)-like
chr10_-_128409632 0.425 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
Nabp2




nucleic acid binding protein 2




chr5_+_14025305 0.419 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_168712853 0.418 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr15_-_37459327 0.408 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr9_+_107296843 0.402 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr18_+_42511496 0.395 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr14_-_121915774 0.386 ENSMUST00000055475.7
Gpr18
G protein-coupled receptor 18
chr1_+_134182404 0.380 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr10_-_95417099 0.378 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr17_-_27728889 0.377 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr17_+_34145231 0.365 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr13_-_41847482 0.364 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr13_-_41847626 0.357 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr7_-_24316590 0.352 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr14_+_56668242 0.351 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr1_-_64121456 0.350 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr11_-_77787747 0.350 ENSMUST00000092883.2
Gm10277
predicted gene 10277
chr15_-_78305603 0.349 ENSMUST00000096356.3
Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr7_+_29816061 0.345 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr12_-_100520778 0.328 ENSMUST00000062957.6
Ttc7b
tetratricopeptide repeat domain 7B
chr9_+_107296682 0.315 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr11_-_106579111 0.312 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chr14_-_70627008 0.310 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr4_+_148140699 0.308 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr17_-_24527830 0.289 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr18_-_33463615 0.287 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr2_-_66634952 0.287 ENSMUST00000100064.2
ENSMUST00000100063.2
Scn9a

sodium channel, voltage-gated, type IX, alpha

chr10_+_20312461 0.284 ENSMUST00000092678.3
ENSMUST00000043881.5
Bclaf1

BCL2-associated transcription factor 1

chr17_-_24527925 0.282 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr4_+_49521176 0.277 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chrX_-_101419788 0.268 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr7_-_78577771 0.267 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr8_+_11728105 0.258 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr7_+_28392916 0.257 ENSMUST00000003529.8
Paf1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr9_+_86571965 0.251 ENSMUST00000034988.3
ENSMUST00000179212.1
Rwdd2a

RWD domain containing 2A

chr7_+_27591705 0.242 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr6_+_127446819 0.239 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr16_+_21794384 0.236 ENSMUST00000180830.1
1300002E11Rik
RIKEN cDNA 1300002E11 gene
chr11_+_101425068 0.235 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr9_+_86743616 0.234 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr18_-_33464007 0.227 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr11_+_78536393 0.224 ENSMUST00000050366.8
ENSMUST00000108275.1
Ift20

intraflagellar transport 20

chr2_+_164403194 0.220 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr18_-_33463747 0.215 ENSMUST00000171533.1
Nrep
neuronal regeneration related protein
chr4_-_140617062 0.212 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_+_18235030 0.208 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chr4_-_11965699 0.199 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr3_-_51560816 0.194 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr5_-_140702241 0.187 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr16_+_17508947 0.177 ENSMUST00000023444.3
Lztr1
leucine-zipper-like transcriptional regulator, 1
chr13_-_34002740 0.167 ENSMUST00000167237.1
ENSMUST00000168400.1
Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

chr15_-_54920115 0.165 ENSMUST00000171545.1
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr16_+_91372865 0.162 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr10_-_95416850 0.160 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr3_+_97032416 0.151 ENSMUST00000132256.1
ENSMUST00000072600.6
Gja5

gap junction protein, alpha 5

chr4_+_83417715 0.150 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr16_+_91372783 0.149 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr19_-_29047847 0.149 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr11_+_78536355 0.132 ENSMUST00000128788.1
Ift20
intraflagellar transport 20
chr11_-_98729374 0.132 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr11_+_3488275 0.128 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr18_-_3281036 0.126 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr8_+_105326354 0.120 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chrX_-_10216918 0.117 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
Rpgr




retinitis pigmentosa GTPase regulator




chr10_+_128303322 0.110 ENSMUST00000005825.6
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_108210438 0.108 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr8_+_25601591 0.107 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr16_+_21794320 0.091 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr13_-_34002784 0.086 ENSMUST00000166354.1
ENSMUST00000076532.7
ENSMUST00000171034.1
Serpinb6a


serine (or cysteine) peptidase inhibitor, clade B, member 6a


chr2_-_37422869 0.082 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr6_+_115134899 0.067 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr7_-_45016224 0.065 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chr9_+_86743641 0.063 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr11_+_82101836 0.060 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr11_-_45955183 0.059 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr16_-_35871544 0.056 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr4_+_11704439 0.053 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr6_-_65144908 0.051 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chr16_+_19760195 0.049 ENSMUST00000121344.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chrX_+_139684980 0.048 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr17_+_35470083 0.044 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10

histocompatibility 2, Q region locus 10

chr7_-_100856289 0.041 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr1_+_134182150 0.041 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr7_-_13053684 0.034 ENSMUST00000182490.1
Mzf1
myeloid zinc finger 1
chr15_-_96460838 0.034 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr2_+_150749036 0.034 ENSMUST00000094467.5
Entpd6
ectonucleoside triphosphate diphosphohydrolase 6
chrX_+_48623737 0.033 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr15_-_97831460 0.031 ENSMUST00000079838.7
ENSMUST00000118294.1
Hdac7

histone deacetylase 7

chr7_-_81829431 0.027 ENSMUST00000026093.7
Btbd1
BTB (POZ) domain containing 1
chr8_-_70608261 0.024 ENSMUST00000049908.9
Ssbp4
single stranded DNA binding protein 4
chr16_+_19760232 0.009 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr2_+_101886249 0.006 ENSMUST00000028584.7
Commd9
COMM domain containing 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 3.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 0.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.7 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 1.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 3.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.0 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.5 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 1.1 GO:0097421 liver regeneration(GO:0097421)
0.1 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.4 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.8 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.0 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0086017 renin secretion into blood stream(GO:0002001) cell communication by chemical coupling(GO:0010643) Purkinje myocyte action potential(GO:0086017) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) regulation of renin secretion into blood stream(GO:1900133)
0.0 0.7 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 1.5 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 2.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.5 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.4 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.4 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 4.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 3.9 GO:0032279 asymmetric synapse(GO:0032279)
0.2 0.7 GO:0090537 CERF complex(GO:0090537)
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.2 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 1.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 1.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 2.7 GO:0045545 syndecan binding(GO:0045545)
0.2 0.7 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.2 1.2 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.1 1.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.6 GO:0001846 opsonin binding(GO:0001846)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0031402 voltage-gated sodium channel activity(GO:0005248) sodium ion binding(GO:0031402)
0.0 1.7 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.7 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 1.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.9 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.9 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 4.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.3 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases