Motif ID: Nkx2-3
Z-value: 1.198

Transcription factors associated with Nkx2-3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nkx2-3 | ENSMUSG00000044220.12 | Nkx2-3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nkx2-3 | mm10_v2_chr19_+_43612299_43612325 | 0.70 | 1.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | GO:0021759 | globus pallidus development(GO:0021759) |
1.3 | 14.7 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.8 | 2.4 | GO:0060166 | olfactory pit development(GO:0060166) |
0.6 | 1.7 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
0.5 | 2.3 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.4 | 0.8 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
0.4 | 1.1 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
0.4 | 3.0 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.3 | 2.1 | GO:0030916 | otic vesicle formation(GO:0030916) |
0.3 | 1.6 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.2 | 1.8 | GO:0097264 | self proteolysis(GO:0097264) |
0.2 | 0.6 | GO:0072720 | response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720) |
0.2 | 0.6 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
0.2 | 0.9 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.2 | 0.5 | GO:0006642 | triglyceride mobilization(GO:0006642) |
0.2 | 0.5 | GO:0016095 | polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310) |
0.1 | 0.4 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.1 | 0.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.1 | 0.3 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.1 | 1.0 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.4 | GO:0099548 | drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) trans-synaptic signaling by nitric oxide(GO:0099548) |
0.1 | 0.5 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.1 | 0.5 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 0.5 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.1 | 0.6 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 0.9 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.3 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
0.1 | 0.5 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 0.7 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
0.1 | 0.5 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.1 | 0.5 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.1 | 0.3 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.1 | 0.6 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.3 | GO:0061357 | Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357) |
0.1 | 0.2 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
0.1 | 4.8 | GO:0021884 | forebrain neuron development(GO:0021884) |
0.1 | 0.7 | GO:0036371 | T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.1 | 0.3 | GO:0015867 | ATP transport(GO:0015867) |
0.1 | 0.2 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.1 | 0.8 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.1 | 0.4 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.1 | 0.2 | GO:0035552 | oxidative single-stranded DNA demethylation(GO:0035552) |
0.1 | 0.2 | GO:1903002 | regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) |
0.1 | 3.0 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.1 | 0.6 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.6 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
0.1 | 0.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.3 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.1 | 2.1 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.2 | GO:0006681 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
0.0 | 0.4 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.5 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.0 | 0.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368) |
0.0 | 0.6 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.3 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.0 | 0.4 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.0 | 0.6 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.0 | 0.2 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.0 | 0.3 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.0 | 0.5 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.2 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.0 | 1.2 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 0.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.0 | 0.3 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
0.0 | 0.1 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
0.0 | 0.2 | GO:0035826 | rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) |
0.0 | 0.6 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 0.6 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
0.0 | 0.1 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.0 | 0.3 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.2 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.0 | 0.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.0 | 0.1 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
0.0 | 1.0 | GO:0007588 | excretion(GO:0007588) |
0.0 | 0.2 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.0 | 2.3 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
0.0 | 0.1 | GO:0060023 | soft palate development(GO:0060023) |
0.0 | 0.4 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 0.4 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.0 | 0.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.0 | 0.2 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 0.3 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 0.1 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.0 | 0.1 | GO:0035937 | androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) testosterone biosynthetic process(GO:0061370) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
0.0 | 0.3 | GO:0014823 | response to activity(GO:0014823) |
0.0 | 0.1 | GO:1901550 | regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140) |
0.0 | 0.3 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.0 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.2 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 1.7 | GO:0030326 | embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113) |
0.0 | 0.4 | GO:0030851 | granulocyte differentiation(GO:0030851) |
0.0 | 0.4 | GO:0072337 | modified amino acid transport(GO:0072337) |
0.0 | 1.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.1 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.0 | 0.3 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.0 | 0.1 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.0 | 0.2 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.0 | GO:0061738 | late endosomal microautophagy(GO:0061738) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
0.0 | 0.5 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.3 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 3.4 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.2 | 2.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.6 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 0.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.5 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.4 | GO:0031523 | Myb complex(GO:0031523) |
0.1 | 1.3 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.1 | 0.2 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.1 | 0.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.1 | 0.3 | GO:0070876 | SOSS complex(GO:0070876) |
0.1 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 2.0 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 0.6 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 2.1 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.3 | GO:0005818 | aster(GO:0005818) |
0.0 | 0.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.2 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
0.0 | 0.9 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 0.1 | GO:0001940 | male pronucleus(GO:0001940) |
0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.1 | GO:0070820 | tertiary granule(GO:0070820) |
0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.0 | 0.5 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 1.3 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.7 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 0.2 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.0 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.2 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.0 | 0.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.2 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.0 | 0.3 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.0 | 0.3 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 0.6 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 7.5 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.3 | 2.3 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.3 | 1.2 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.2 | 2.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.2 | 0.5 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.2 | 0.5 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.2 | 2.4 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 1.7 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 0.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 0.9 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.6 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.4 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 3.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.1 | 0.4 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
0.1 | 0.3 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
0.1 | 0.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 0.5 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 2.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.5 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.1 | 0.3 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.1 | 0.4 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.1 | 0.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.1 | 0.2 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.1 | 0.5 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.1 | 1.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 0.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.3 | GO:0034046 | poly(G) binding(GO:0034046) |
0.0 | 0.3 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.0 | 0.3 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.0 | 0.3 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.0 | 0.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.7 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.2 | GO:0043734 | DNA-N1-methyladenine dioxygenase activity(GO:0043734) |
0.0 | 0.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.0 | 0.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.3 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
0.0 | 0.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.0 | 0.5 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.9 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
0.0 | 0.5 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.0 | 0.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.0 | 0.2 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.1 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.0 | 9.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 1.6 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 1.4 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.0 | 0.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.1 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
0.0 | 0.9 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.8 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.1 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 0.1 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 1.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.4 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.3 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.0 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.2 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.0 | 0.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 14.2 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 3.9 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 2.8 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.4 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 1.3 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 1.1 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 2.0 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.6 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.0 | 0.5 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
0.0 | 2.2 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 1.0 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.0 | 0.6 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.4 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.3 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 0.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.4 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 0.7 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.3 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 0.5 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.1 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.1 | 2.3 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.1 | 1.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 0.4 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.5 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 1.1 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.9 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 0.2 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
0.0 | 0.3 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.5 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.0 | 0.2 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 2.0 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.3 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.5 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 0.4 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 0.2 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.2 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.3 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.1 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |