Motif ID: Gzf1

Z-value: 0.430


Transcription factors associated with Gzf1:

Gene SymbolEntrez IDGene Name
Gzf1 ENSMUSG00000027439.9 Gzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gzf1mm10_v2_chr2_+_148681023_148681197-0.781.4e-04Click!


Activity profile for motif Gzf1.

activity profile for motif Gzf1


Sorted Z-values histogram for motif Gzf1

Sorted Z-values for motif Gzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 1.290 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr14_+_19751257 1.276 ENSMUST00000022340.3
Nid2
nidogen 2
chr11_-_33163072 0.997 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
Npm1



nucleophosmin 1



chr17_+_47594629 0.857 ENSMUST00000182846.1
Ccnd3
cyclin D3
chr8_-_78508876 0.812 ENSMUST00000049245.7
Rbmxl1
RNA binding motif protein, X linked-like-1
chr17_-_55915870 0.807 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr4_-_129542710 0.792 ENSMUST00000102597.4
Hdac1
histone deacetylase 1
chr2_-_93996354 0.721 ENSMUST00000183110.1
Gm27027
predicted gene, 27027
chr13_+_37826225 0.706 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr4_+_129513581 0.690 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr16_+_65815508 0.650 ENSMUST00000168064.1
Vgll3
vestigial like 3 (Drosophila)
chr14_+_11227511 0.620 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr7_-_30612731 0.544 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr8_+_105855086 0.538 ENSMUST00000040445.7
Thap11
THAP domain containing 11
chr4_-_134128707 0.505 ENSMUST00000105879.1
ENSMUST00000030651.8
Sh3bgrl3

SH3 domain binding glutamic acid-rich protein-like 3

chr14_+_55854115 0.424 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr2_+_162931520 0.380 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr1_+_15805639 0.288 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr14_+_55853997 0.176 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr10_+_82699007 0.175 ENSMUST00000020478.7
Hcfc2
host cell factor C2
chr2_-_153632775 0.103 ENSMUST00000071852.3
Commd7
COMM domain containing 7
chr8_+_78509319 0.058 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr2_+_29827342 0.015 ENSMUST00000091142.3
Urm1
ubiquitin related modifier 1 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.3 1.3 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.8 GO:0061198 fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.7 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.6 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.0 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0001652 granular component(GO:0001652)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 1.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 PID_CDC42_PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription