Motif ID: Hsfy2
Z-value: 0.946

Transcription factors associated with Hsfy2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hsfy2 | ENSMUSG00000045336.4 | Hsfy2 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0070366 | regulation of hepatocyte differentiation(GO:0070366) |
0.7 | 2.0 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
0.6 | 1.8 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.5 | 2.2 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.4 | 1.3 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
0.4 | 2.1 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.4 | 1.2 | GO:0002432 | granuloma formation(GO:0002432) |
0.4 | 1.2 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.4 | 1.8 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
0.4 | 1.1 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
0.4 | 0.7 | GO:0002159 | desmosome assembly(GO:0002159) |
0.3 | 1.9 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.3 | 0.8 | GO:0002314 | germinal center B cell differentiation(GO:0002314) positive regulation of germinal center formation(GO:0002636) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) xanthine metabolic process(GO:0046110) purine deoxyribonucleoside metabolic process(GO:0046122) regulation of adenosine receptor signaling pathway(GO:0060167) negative regulation of mucus secretion(GO:0070256) |
0.2 | 0.7 | GO:0061744 | motor behavior(GO:0061744) |
0.2 | 1.4 | GO:0044351 | macropinocytosis(GO:0044351) |
0.2 | 1.6 | GO:0070458 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
0.2 | 0.7 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.2 | 0.9 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.2 | 1.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.2 | 1.2 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
0.2 | 0.7 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
0.2 | 0.5 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
0.2 | 0.9 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
0.2 | 1.4 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.2 | 0.5 | GO:0051715 | cytolysis in other organism(GO:0051715) |
0.2 | 0.6 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.2 | 0.9 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
0.1 | 0.4 | GO:2000373 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
0.1 | 0.4 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.1 | 0.4 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
0.1 | 0.4 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.1 | 0.6 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.1 | 2.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.1 | 1.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 0.2 | GO:0033864 | positive regulation of NAD(P)H oxidase activity(GO:0033864) |
0.1 | 4.1 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
0.1 | 0.4 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
0.1 | 1.4 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.1 | 0.8 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.1 | 1.0 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.1 | 2.4 | GO:0070884 | short-term memory(GO:0007614) regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
0.1 | 1.4 | GO:0036093 | germ cell proliferation(GO:0036093) |
0.1 | 1.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.1 | 0.3 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.1 | 1.9 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 1.8 | GO:0003334 | keratinocyte development(GO:0003334) |
0.1 | 0.3 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
0.1 | 0.3 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
0.1 | 2.0 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.1 | 0.7 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
0.1 | 0.3 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 0.6 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
0.1 | 0.3 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
0.1 | 0.9 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.1 | 1.1 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.1 | 1.0 | GO:0060068 | vagina development(GO:0060068) |
0.1 | 1.3 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
0.1 | 0.2 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.1 | 0.3 | GO:0001692 | histamine metabolic process(GO:0001692) |
0.1 | 1.0 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.1 | 0.7 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
0.1 | 0.2 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.1 | 0.4 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
0.1 | 0.2 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
0.1 | 0.5 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.1 | 0.3 | GO:0060368 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
0.1 | 0.3 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
0.1 | 0.1 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.1 | 1.1 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.1 | 0.4 | GO:0042730 | fibrinolysis(GO:0042730) |
0.1 | 0.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.1 | 0.5 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.1 | 0.2 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.1 | 0.6 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.1 | 0.2 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
0.1 | 0.3 | GO:1903232 | melanosome assembly(GO:1903232) |
0.1 | 0.3 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.1 | 0.8 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
0.1 | 1.0 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.1 | 0.2 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
0.0 | 0.6 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 1.1 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.2 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.0 | 0.7 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
0.0 | 0.2 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.0 | 0.4 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 1.6 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
0.0 | 0.9 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 1.0 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.0 | 0.6 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
0.0 | 1.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.3 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
0.0 | 0.1 | GO:0019062 | virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650) |
0.0 | 0.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.2 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
0.0 | 0.2 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 1.0 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.7 | GO:0000469 | cleavage involved in rRNA processing(GO:0000469) |
0.0 | 0.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.0 | 1.7 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 0.3 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
0.0 | 0.1 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
0.0 | 1.2 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
0.0 | 0.2 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
0.0 | 1.1 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.2 | GO:0036035 | osteoclast development(GO:0036035) |
0.0 | 0.2 | GO:0070508 | sterol import(GO:0035376) cholesterol import(GO:0070508) |
0.0 | 1.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.0 | 0.5 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.0 | 1.1 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
0.0 | 0.3 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.0 | 0.2 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.0 | 0.2 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
0.0 | 0.3 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.0 | GO:0009826 | unidimensional cell growth(GO:0009826) |
0.0 | 0.4 | GO:0050832 | defense response to fungus(GO:0050832) |
0.0 | 2.3 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
0.0 | 0.7 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.4 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
0.0 | 1.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 1.0 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
0.0 | 0.7 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.0 | 1.1 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.0 | 0.1 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
0.0 | 0.0 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
0.0 | 0.1 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
0.0 | 1.8 | GO:0042476 | odontogenesis(GO:0042476) |
0.0 | 0.1 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
0.0 | 0.8 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
0.0 | 0.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.5 | GO:0006301 | postreplication repair(GO:0006301) |
0.0 | 0.1 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
0.0 | 0.0 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
0.0 | 0.3 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
0.0 | 4.9 | GO:0008380 | RNA splicing(GO:0008380) |
0.0 | 0.1 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177) |
0.0 | 0.8 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.7 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.0 | 0.6 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
0.0 | 0.1 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.7 | GO:0006289 | nucleotide-excision repair(GO:0006289) |
0.0 | 0.4 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
0.0 | 0.1 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
0.0 | 0.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 0.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 4.3 | GO:0005818 | aster(GO:0005818) |
0.4 | 1.2 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.4 | 1.1 | GO:0000801 | central element(GO:0000801) |
0.3 | 1.3 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.3 | 0.9 | GO:1990423 | RZZ complex(GO:1990423) |
0.3 | 3.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.2 | 0.9 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
0.2 | 2.1 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.2 | 0.5 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.2 | 0.6 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.2 | 0.6 | GO:0061702 | inflammasome complex(GO:0061702) |
0.1 | 0.6 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 0.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.1 | 0.8 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 1.1 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.1 | 3.1 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.1 | 0.4 | GO:0018444 | translation release factor complex(GO:0018444) |
0.1 | 0.9 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 0.3 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.1 | 0.3 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
0.1 | 0.3 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.1 | 0.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.1 | 1.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.1 | 0.9 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.1 | 0.4 | GO:0005688 | U6 snRNP(GO:0005688) |
0.1 | 4.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.1 | 0.7 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 1.5 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.1 | 1.1 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.1 | 1.4 | GO:0097526 | spliceosomal tri-snRNP complex(GO:0097526) |
0.1 | 0.7 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 0.5 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.1 | 0.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.1 | 0.7 | GO:0045095 | keratin filament(GO:0045095) |
0.1 | 2.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.1 | 1.7 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 3.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.7 | GO:0031091 | platelet alpha granule(GO:0031091) |
0.0 | 0.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.0 | 0.7 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.0 | 0.2 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.0 | 0.3 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.0 | 1.0 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.5 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 1.9 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.3 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.2 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.5 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 1.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 0.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 1.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
0.0 | 0.6 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.5 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.0 | 1.0 | GO:0031672 | A band(GO:0031672) |
0.0 | 1.8 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.8 | GO:0030686 | 90S preribosome(GO:0030686) |
0.0 | 0.1 | GO:0005638 | lamin filament(GO:0005638) |
0.0 | 1.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.1 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 2.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.9 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.3 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.1 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 0.6 | GO:0000793 | condensed chromosome(GO:0000793) |
0.0 | 0.8 | GO:0005657 | replication fork(GO:0005657) |
0.0 | 1.0 | GO:0005840 | ribosome(GO:0005840) |
0.0 | 0.3 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 1.2 | GO:0000922 | spindle pole(GO:0000922) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.4 | 1.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.4 | 2.4 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.4 | 3.5 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.4 | 1.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.4 | 1.1 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.3 | 2.1 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.3 | 0.9 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
0.3 | 1.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.3 | 0.8 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.2 | 1.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.2 | 0.7 | GO:0009041 | uridylate kinase activity(GO:0009041) |
0.2 | 1.3 | GO:0008494 | translation activator activity(GO:0008494) |
0.2 | 1.1 | GO:0004359 | glutaminase activity(GO:0004359) |
0.2 | 1.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.2 | 1.2 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.2 | 0.8 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
0.2 | 1.4 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.2 | 1.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.1 | 1.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.1 | 2.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 0.5 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.1 | 0.6 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.1 | 0.9 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 1.1 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 0.5 | GO:0050700 | CARD domain binding(GO:0050700) |
0.1 | 0.6 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.1 | 0.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 2.0 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 0.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.1 | 0.6 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 0.9 | GO:1990405 | protein antigen binding(GO:1990405) |
0.1 | 2.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 1.6 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.3 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
0.1 | 0.4 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.1 | 2.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 1.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.1 | 0.4 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.1 | 0.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.1 | 0.4 | GO:0000405 | bubble DNA binding(GO:0000405) |
0.1 | 0.6 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.1 | 0.5 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.1 | 0.4 | GO:0034046 | poly(G) binding(GO:0034046) |
0.1 | 0.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.1 | 0.7 | GO:0015266 | protein channel activity(GO:0015266) |
0.1 | 0.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.1 | 0.8 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.1 | 0.5 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.1 | 0.2 | GO:0032052 | bile acid binding(GO:0032052) |
0.1 | 0.9 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 1.6 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.1 | 0.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 0.6 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.5 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.1 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 1.0 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 1.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.4 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.0 | 0.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.3 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.1 | GO:0036004 | GAF domain binding(GO:0036004) |
0.0 | 0.2 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.0 | 0.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.1 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.0 | 0.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.6 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.6 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 1.1 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 1.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.3 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
0.0 | 1.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.0 | 0.4 | GO:0051400 | BH domain binding(GO:0051400) |
0.0 | 1.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0003883 | CTP synthase activity(GO:0003883) |
0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 2.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 3.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 1.3 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
0.0 | 0.9 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 1.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.5 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.3 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.0 | 0.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.0 | 0.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 1.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.1 | GO:0048256 | flap endonuclease activity(GO:0048256) |
0.0 | 0.4 | GO:0051536 | iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540) |
0.0 | 0.2 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
0.0 | 0.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.2 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.1 | 0.8 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 3.5 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.1 | 3.4 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 1.6 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 1.3 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 1.8 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 1.9 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.8 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 1.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 3.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 1.1 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 1.0 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.0 | 0.4 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 2.2 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.2 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.3 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 0.4 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 0.9 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.0 | 1.1 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.0 | 1.1 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
0.0 | 0.2 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 0.7 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.4 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.1 | 1.0 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PI | Genes involved in Acyl chain remodelling of PI |
0.1 | 1.8 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.1 | 0.7 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.1 | 0.6 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.1 | 3.9 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.1 | 1.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 0.8 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.1 | 2.7 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.1 | 4.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.1 | 1.6 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 0.2 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.1 | 1.1 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.1 | 0.4 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.0 | 0.8 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.8 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 1.1 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 2.2 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 1.7 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.8 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.7 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.0 | 0.6 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.8 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.5 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
0.0 | 0.3 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.3 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 1.3 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.8 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.3 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 1.4 | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
0.0 | 0.2 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
0.0 | 1.9 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.9 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.7 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 1.5 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.4 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.4 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
0.0 | 1.5 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.0 | 1.1 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.2 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
0.0 | 0.7 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.5 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.4 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.5 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.3 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.3 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.3 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
0.0 | 0.3 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |