Motif ID: Elf3

Z-value: 1.071


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.106.9e-01Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_35049966 1.748 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr2_+_164562579 1.553 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr2_+_126215100 1.265 ENSMUST00000164042.2
Gm17555
predicted gene, 17555
chr10_+_79988584 1.219 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr1_+_138963709 1.207 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr11_+_61653259 1.087 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr13_-_41847482 1.075 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr10_-_83648713 1.044 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chrX_+_169685191 1.030 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr11_-_48816936 1.005 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr1_+_51987139 0.982 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr12_-_65172560 0.981 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr3_-_146499721 0.919 ENSMUST00000029839.4
Spata1
spermatogenesis associated 1
chr6_-_146502141 0.892 ENSMUST00000079573.6
ENSMUST00000139732.1
Itpr2

inositol 1,4,5-triphosphate receptor 2

chr19_+_16435616 0.889 ENSMUST00000025602.2
Gna14
guanine nucleotide binding protein, alpha 14
chr6_-_23248264 0.888 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr14_-_57890242 0.861 ENSMUST00000089473.3
Zdhhc20
zinc finger, DHHC domain containing 20
chr1_+_16688405 0.859 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr2_-_73580288 0.852 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr8_-_71395794 0.849 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr7_-_3677509 0.827 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr11_-_70654598 0.801 ENSMUST00000108549.1
Pfn1
profilin 1
chr7_-_101933780 0.789 ENSMUST00000106964.1
ENSMUST00000078448.3
Lrrc51

leucine rich repeat containing 51

chr3_-_51396528 0.767 ENSMUST00000038154.5
Mgarp
mitochondria localized glutamic acid rich protein
chr7_-_44375006 0.758 ENSMUST00000107933.1
1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr3_-_51396716 0.743 ENSMUST00000141156.1
Mgarp
mitochondria localized glutamic acid rich protein
chr15_-_78803015 0.733 ENSMUST00000164826.1
Card10
caspase recruitment domain family, member 10
chr11_+_111066154 0.729 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr13_-_103920508 0.728 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr11_-_70654624 0.724 ENSMUST00000018437.2
Pfn1
profilin 1
chr4_-_106464167 0.697 ENSMUST00000049507.5
Pcsk9
proprotein convertase subtilisin/kexin type 9
chr6_+_29694204 0.688 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr9_-_120068263 0.675 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr11_+_53770014 0.669 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr3_-_51396502 0.666 ENSMUST00000108046.1
Mgarp
mitochondria localized glutamic acid rich protein
chr7_-_102250086 0.665 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr12_-_57546121 0.662 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr6_-_48708206 0.645 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr19_+_8850785 0.634 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr13_-_41847626 0.629 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chrX_-_8090442 0.623 ENSMUST00000033505.6
Was
Wiskott-Aldrich syndrome homolog (human)
chr2_+_165055625 0.619 ENSMUST00000017799.5
ENSMUST00000073707.2
Cd40

CD40 antigen

chr14_-_70207637 0.617 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr11_-_106388066 0.609 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr11_-_48817332 0.604 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr15_+_79516396 0.599 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr14_+_25983005 0.598 ENSMUST00000049793.8
Duxbl1
double homeobox B-like 1
chr3_+_146499850 0.591 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr3_+_146499828 0.588 ENSMUST00000090031.5
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr7_-_101933815 0.586 ENSMUST00000106963.1
ENSMUST00000106966.1
Lrrc51

leucine rich repeat containing 51

chr11_-_55419898 0.586 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr17_+_86963279 0.583 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr14_-_20496780 0.583 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr14_+_34673888 0.582 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr6_+_48739039 0.575 ENSMUST00000054368.4
ENSMUST00000140054.1
Gimap1

GTPase, IMAP family member 1

chr4_-_14621669 0.570 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr14_-_8309770 0.568 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr10_+_83543941 0.565 ENSMUST00000038388.5
A230046K03Rik
RIKEN cDNA A230046K03 gene
chr17_-_25880236 0.562 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr7_+_27486910 0.556 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr4_-_14621494 0.555 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr1_+_84839833 0.548 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr6_-_146502099 0.539 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr4_-_14621805 0.536 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr2_-_148045891 0.532 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr11_+_53770458 0.527 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr15_+_55557399 0.524 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr7_-_80232479 0.522 ENSMUST00000123279.1
Cib1
calcium and integrin binding 1 (calmyrin)
chr13_-_103920295 0.515 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr2_-_30474199 0.514 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr2_+_31572651 0.511 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr16_+_62854299 0.502 ENSMUST00000023629.8
Pros1
protein S (alpha)
chr10_+_94198955 0.495 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr4_-_118489755 0.491 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_15720654 0.476 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr1_+_15805639 0.475 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr9_-_66919646 0.468 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr4_-_63403330 0.458 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr10_-_23787195 0.454 ENSMUST00000073926.6
Rps12
ribosomal protein S12
chr7_+_105640448 0.454 ENSMUST00000058333.3
Timm10b
translocase of inner mitochondrial membrane 10B
chr3_-_84582476 0.449 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr12_+_109544498 0.438 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr14_-_54577578 0.435 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr3_-_89418287 0.431 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr17_+_86753900 0.429 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr3_+_87919490 0.429 ENSMUST00000019854.6
ENSMUST00000119968.1
Mrpl24

mitochondrial ribosomal protein L24

chr7_-_34655500 0.421 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr19_+_46305682 0.412 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_-_72980402 0.412 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3

trans-acting transcription factor 3

chr1_+_170308802 0.404 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr7_+_101378183 0.404 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_-_20898592 0.403 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr15_-_36608959 0.402 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr7_+_30563838 0.401 ENSMUST00000163330.1
U2af1l4
U2 small nuclear RNA auxiliary factor 1-like 4
chr4_+_44756553 0.396 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr3_+_90603767 0.394 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr7_-_81345189 0.386 ENSMUST00000080813.4
Rps17
ribosomal protein S17
chr3_+_96645579 0.385 ENSMUST00000119365.1
ENSMUST00000029744.5
Itga10

integrin, alpha 10

chr7_+_119793987 0.385 ENSMUST00000033218.8
ENSMUST00000106520.1
2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr3_+_145576196 0.377 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr12_-_69357120 0.377 ENSMUST00000021368.8
Nemf
nuclear export mediator factor
chr4_+_108847827 0.377 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr7_+_105640522 0.373 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
Timm10b



translocase of inner mitochondrial membrane 10B



chr8_-_83442648 0.362 ENSMUST00000167525.1
Scoc
short coiled-coil protein
chr6_-_124741374 0.360 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr18_-_3281036 0.360 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr3_-_116614587 0.358 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr18_+_56432116 0.357 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr5_+_110330697 0.356 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr1_-_161876656 0.353 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr3_-_52104891 0.352 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr1_-_84839304 0.350 ENSMUST00000027421.6
Trip12
thyroid hormone receptor interactor 12
chr5_+_108065742 0.348 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr4_-_136053343 0.346 ENSMUST00000102536.4
Rpl11
ribosomal protein L11
chr17_-_47834682 0.341 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr11_+_120598421 0.341 ENSMUST00000026128.3
Anapc11
anaphase promoting complex subunit 11
chr1_-_13589717 0.339 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr7_+_101896340 0.338 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr7_-_29155717 0.338 ENSMUST00000153251.1
Fam98c
family with sequence similarity 98, member C
chr9_+_44407629 0.338 ENSMUST00000080300.7
Rps25
ribosomal protein S25
chr10_-_30655859 0.337 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr2_+_31470207 0.325 ENSMUST00000102840.4
Ass1
argininosuccinate synthetase 1
chr17_+_31057686 0.324 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr7_+_119794102 0.323 ENSMUST00000084644.2
2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr14_-_54253907 0.322 ENSMUST00000128231.1
Dad1
defender against cell death 1
chr10_+_80249106 0.322 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr4_+_42158092 0.322 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr14_+_31208309 0.320 ENSMUST00000169169.1
Tnnc1
troponin C, cardiac/slow skeletal
chr10_-_62231208 0.311 ENSMUST00000047883.9
Tspan15
tetraspanin 15
chr5_-_34637203 0.311 ENSMUST00000114331.3
Mfsd10
major facilitator superfamily domain containing 10
chr10_+_93540626 0.310 ENSMUST00000092215.5
Ccdc38
coiled-coil domain containing 38
chr6_+_71272019 0.310 ENSMUST00000168700.1
Krcc1
lysine-rich coiled-coil 1
chr14_+_34375504 0.308 ENSMUST00000111908.1
Mmrn2
multimerin 2
chr2_+_31670714 0.308 ENSMUST00000038474.7
ENSMUST00000137156.1
Exosc2

exosome component 2

chr16_-_24393588 0.307 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr10_+_80249441 0.306 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr5_-_34637107 0.305 ENSMUST00000124668.1
ENSMUST00000001109.4
ENSMUST00000155577.1
ENSMUST00000114329.1
Mfsd10



major facilitator superfamily domain containing 10



chr4_-_156255327 0.301 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr9_+_6168601 0.297 ENSMUST00000168039.1
Pdgfd
platelet-derived growth factor, D polypeptide
chr11_-_17008647 0.294 ENSMUST00000102881.3
Plek
pleckstrin
chr19_-_50678485 0.289 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr7_+_102065713 0.289 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr6_-_24515036 0.288 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr1_+_72711259 0.280 ENSMUST00000059980.9
Rpl37a
ribosomal protein L37a
chr8_+_104340594 0.276 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr9_+_35559460 0.275 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr6_-_24527546 0.271 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr16_+_24393350 0.269 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_23572038 0.264 ENSMUST00000132484.1
Spopl
speckle-type POZ protein-like
chr18_-_62756275 0.260 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr14_-_11356726 0.260 ENSMUST00000181173.1
Gm3839
predicted pseudogene 3839
chr7_-_25477607 0.256 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr8_+_3493135 0.255 ENSMUST00000061508.7
Zfp358
zinc finger protein 358
chr5_-_105343929 0.255 ENSMUST00000183149.1
Gbp11
guanylate binding protein 11
chr11_+_51261719 0.254 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr1_+_36307745 0.250 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr3_-_51560816 0.250 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr9_-_54647199 0.249 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr3_+_90051630 0.244 ENSMUST00000159064.1
4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr5_+_115845229 0.241 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr4_-_40722307 0.240 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr15_-_55557748 0.239 ENSMUST00000172387.1
Mrpl13
mitochondrial ribosomal protein L13
chr11_-_100850724 0.238 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr1_-_4496400 0.238 ENSMUST00000027035.3
Sox17
SRY-box containing gene 17
chr10_+_76449074 0.236 ENSMUST00000092406.5
2610028H24Rik
RIKEN cDNA 2610028H24 gene
chr17_+_21733704 0.236 ENSMUST00000183192.1
ENSMUST00000065871.7
Zfp229

zinc finger protein 229

chr2_+_105904629 0.234 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_-_13037627 0.231 ENSMUST00000125964.1
Ube2m
ubiquitin-conjugating enzyme E2M
chr2_+_26581050 0.229 ENSMUST00000166920.2
Egfl7
EGF-like domain 7
chr5_+_33983437 0.225 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr4_-_156228540 0.224 ENSMUST00000105571.2
Plekhn1
pleckstrin homology domain containing, family N member 1
chr16_+_19760232 0.223 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr3_-_122984404 0.219 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chrX_-_88760312 0.214 ENSMUST00000182943.1
Gm27000
predicted gene, 27000
chr12_-_80260356 0.213 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr14_-_31830402 0.209 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr19_+_5740885 0.206 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr3_-_146839365 0.205 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr4_-_117887292 0.200 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr1_+_58795371 0.200 ENSMUST00000027189.8
Casp8
caspase 8
chr11_-_97150025 0.200 ENSMUST00000118375.1
Tbkbp1
TBK1 binding protein 1
chr5_+_17574268 0.197 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_150237694 0.197 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr10_-_89443888 0.195 ENSMUST00000099374.2
ENSMUST00000105298.1
Gas2l3

growth arrest-specific 2 like 3

chr17_-_63499983 0.192 ENSMUST00000024761.6
Fbxl17
F-box and leucine-rich repeat protein 17
chr15_-_83432819 0.189 ENSMUST00000165095.1
Pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr3_+_87919563 0.188 ENSMUST00000121920.1
Mrpl24
mitochondrial ribosomal protein L24
chr8_+_25720054 0.185 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr14_+_34673948 0.182 ENSMUST00000090027.3
Wapal
wings apart-like homolog (Drosophila)
chr1_+_136467958 0.182 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr11_+_78324200 0.180 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr4_+_40722912 0.175 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr11_-_103344651 0.173 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr4_+_53826014 0.169 ENSMUST00000030127.6
Tmem38b
transmembrane protein 38B
chr19_+_6363671 0.163 ENSMUST00000131252.1
Sf1
splicing factor 1
chr11_+_117232254 0.162 ENSMUST00000106354.2
Sept9
septin 9
chr5_-_30155101 0.161 ENSMUST00000156859.1
Hadha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
chr2_+_20737306 0.160 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr3_+_89418443 0.155 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chr9_-_43116514 0.153 ENSMUST00000061833.4
Tmem136
transmembrane protein 136

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.4 1.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 1.7 GO:0019532 oxalate transport(GO:0019532)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.2 1.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 1.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.5 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743)
0.2 1.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 0.5 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 0.7 GO:0001920 negative regulation of receptor recycling(GO:0001920) negative regulation of low-density lipoprotein particle clearance(GO:0010989) positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.2 0.9 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.7 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.5 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.1 0.3 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.6 GO:0042891 antibiotic transport(GO:0042891)
0.1 0.2 GO:0032817 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819)
0.1 0.5 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.1 0.4 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 0.3 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.3 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0060913 stem cell fate specification(GO:0048866) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043)
0.1 0.3 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.4 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.1 0.4 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.1 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.6 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.5 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0034436 low-density lipoprotein particle remodeling(GO:0034374) glycoprotein transport(GO:0034436)
0.1 1.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.4 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:1990839 response to endothelin(GO:1990839)
0.0 0.4 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.8 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.6 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.6 GO:0043392 negative regulation of DNA binding(GO:0043392)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 0.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.5 GO:0070187 telosome(GO:0070187)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 3.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0031105 septin complex(GO:0031105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 0.3 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.3 1.6 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 0.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.7 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.2 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.7 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.6 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.3 GO:0031014 troponin T binding(GO:0031014)
0.1 0.5 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0070739 NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 4.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 2.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 0.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.9 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.9 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 2.0 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 2.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.0 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation