Motif ID: Nkx6-3_Dbx2_Barx2

Z-value: 0.462

Transcription factors associated with Nkx6-3_Dbx2_Barx2:

Gene SymbolEntrez IDGene Name
Barx2 ENSMUSG00000032033.10 Barx2
Dbx2 ENSMUSG00000045608.6 Dbx2
Nkx6-3 ENSMUSG00000063672.6 Nkx6-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbx2mm10_v2_chr15_-_95655960_956559600.653.3e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-3_Dbx2_Barx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_102589687 1.923 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr14_+_80000292 1.793 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr16_+_11406618 1.645 ENSMUST00000122168.1
Snx29
sorting nexin 29
chrX_-_143933089 1.464 ENSMUST00000087313.3
Dcx
doublecortin
chr4_-_14621805 1.439 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr13_+_94083490 1.396 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr17_-_81649607 1.347 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr10_-_110000219 1.326 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr5_-_118244861 1.063 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr5_-_62766153 0.896 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr13_+_83732438 0.881 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr9_-_15301555 0.845 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chrX_-_143933204 0.818 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr8_+_34054622 0.731 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr5_-_70842617 0.729 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr13_-_105054895 0.702 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr17_+_26715644 0.652 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr9_+_67840386 0.646 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr5_+_144100387 0.608 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr10_+_23797052 0.588 ENSMUST00000133289.1
Slc18b1
solute carrier family 18, subfamily B, member 1
chr13_+_109926832 0.577 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr15_-_33687840 0.574 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr4_-_108301045 0.548 ENSMUST00000043616.6
Zyg11b
zyg-ll family member B, cell cycle regulator
chr1_+_72284367 0.545 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr3_-_116712644 0.536 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_+_13743424 0.527 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_-_105271039 0.520 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr15_-_8710409 0.494 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_29195983 0.480 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr7_+_79273201 0.475 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr4_-_14621494 0.448 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr9_+_113812547 0.431 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr14_-_100149764 0.420 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr19_-_57239310 0.391 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr8_-_70212268 0.367 ENSMUST00000110127.1
Slc25a42
solute carrier family 25, member 42
chr18_+_23753708 0.363 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr8_-_70212251 0.361 ENSMUST00000063788.7
Slc25a42
solute carrier family 25, member 42
chr2_-_73580288 0.339 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr15_-_8710734 0.333 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_45112890 0.321 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_125782834 0.315 ENSMUST00000053699.6
Secisbp2l
SECIS binding protein 2-like
chr2_+_55437100 0.315 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr4_+_118961578 0.313 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr14_-_75754475 0.299 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr15_+_82252397 0.290 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr8_+_40354303 0.270 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr3_+_5218516 0.268 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr2_+_69897220 0.263 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr3_-_62506970 0.257 ENSMUST00000029336.4
Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr7_+_57387304 0.252 ENSMUST00000085241.5
Gm9962
predicted gene 9962
chr7_+_39588931 0.239 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr2_-_113829069 0.236 ENSMUST00000024005.7
Scg5
secretogranin V
chr4_-_40722307 0.226 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr2_+_23069210 0.215 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr3_+_94837702 0.210 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr7_+_123123870 0.209 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr17_-_36032682 0.202 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr7_-_57387172 0.195 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr3_+_5218589 0.189 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr2_-_177267036 0.185 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr14_+_4198185 0.185 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr10_+_75037291 0.176 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr9_+_53771499 0.167 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr10_+_79996479 0.165 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr6_+_37870786 0.155 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr3_+_32436151 0.153 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr12_+_72536342 0.149 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chrX_+_16619698 0.148 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr7_+_103550368 0.148 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr2_-_5895319 0.146 ENSMUST00000026926.4
ENSMUST00000102981.3
Sec61a2

Sec61, alpha subunit 2 (S. cerevisiae)

chr18_+_37655891 0.144 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr18_+_57468478 0.142 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr6_+_145934113 0.134 ENSMUST00000032383.7
Sspn
sarcospan
chr10_+_23894688 0.131 ENSMUST00000041416.7
Vnn1
vanin 1
chr18_-_24603464 0.126 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr10_-_117148474 0.121 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chrX_-_157415286 0.120 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr10_+_50592669 0.119 ENSMUST00000035606.8
Ascc3
activating signal cointegrator 1 complex subunit 3
chr11_+_51261719 0.118 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr17_+_22424248 0.116 ENSMUST00000120222.1
Zfp946
zinc finger protein 946
chr15_-_75905349 0.116 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr11_+_78037931 0.110 ENSMUST00000072289.5
ENSMUST00000100784.2
Flot2

flotillin 2

chr3_+_94837533 0.110 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr11_+_78037959 0.109 ENSMUST00000073660.6
Flot2
flotillin 2
chr7_-_133702515 0.108 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr2_+_69670100 0.107 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr19_-_32196393 0.106 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr17_+_22424261 0.105 ENSMUST00000088763.6
Zfp946
zinc finger protein 946
chr2_+_36230426 0.104 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr2_+_110597298 0.104 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr9_+_100597686 0.099 ENSMUST00000124487.1
Stag1
stromal antigen 1
chr18_+_59062462 0.099 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr3_+_5218546 0.098 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr7_-_80405425 0.095 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr11_+_102285161 0.093 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr11_-_107337556 0.091 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_129378116 0.088 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chr18_+_24603952 0.081 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr18_-_24603791 0.078 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr4_-_149126688 0.078 ENSMUST00000030815.2
Cort
cortistatin
chr18_+_55057557 0.075 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr4_+_146610961 0.070 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr2_-_84715160 0.069 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr8_+_107031218 0.066 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr4_+_145585166 0.065 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr18_-_43477764 0.063 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr1_-_168432270 0.063 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr12_-_20900867 0.062 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr4_+_147492417 0.060 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr17_-_50094277 0.059 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr8_+_72219726 0.054 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr10_-_86011833 0.054 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr9_+_110052016 0.047 ENSMUST00000164930.1
ENSMUST00000163979.1
Map4

microtubule-associated protein 4

chr2_-_84650676 0.037 ENSMUST00000067232.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr7_+_19119853 0.036 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr4_+_136143497 0.035 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr4_-_147809788 0.035 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr12_+_102128718 0.032 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr18_+_59062282 0.029 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr1_+_194619815 0.028 ENSMUST00000027952.5
Plxna2
plexin A2
chr5_-_34660068 0.025 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr10_+_75037066 0.021 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr2_-_84650714 0.018 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
Ctnnd1



















catenin (cadherin associated protein), delta 1



















chr2_+_32606979 0.018 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

chr6_-_122340525 0.016 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr2_-_86347764 0.014 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr2_-_84650490 0.012 ENSMUST00000066177.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr17_-_32886083 0.010 ENSMUST00000178401.1
Zfp870
zinc finger protein 870
chr13_-_21468474 0.006 ENSMUST00000068235.4
Nkapl
NFKB activating protein-like
chr18_-_23981555 0.005 ENSMUST00000115829.1
Zscan30
zinc finger and SCAN domain containing 30
chr4_-_14621669 0.004 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr7_-_45103747 0.004 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr1_+_139454747 0.004 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr4_+_147132038 0.004 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr19_-_23273893 0.000 ENSMUST00000087556.5
Smc5
structural maintenance of chromosomes 5

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0019532 oxalate transport(GO:0019532)
0.3 1.3 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.2 0.7 GO:0015866 ADP transport(GO:0015866)
0.2 0.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 2.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.6 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.2 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.5 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0033089 chronic inflammatory response(GO:0002544) positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 2.9 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 0.7 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 1.9 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 2.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0022857 transmembrane transporter activity(GO:0022857)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 2.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins