Motif ID: Mga

Z-value: 0.302


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.455.8e-02Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 1.742 ENSMUST00000168589.1
Sla
src-like adaptor
chr15_-_43869993 0.742 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr10_+_81575257 0.606 ENSMUST00000135211.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr10_+_81575306 0.603 ENSMUST00000146916.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr13_+_29016267 0.563 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr11_+_49203465 0.447 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr2_+_85136355 0.423 ENSMUST00000057019.7
Aplnr
apelin receptor
chr11_+_49203285 0.420 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr5_-_138619751 0.354 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68

zinc finger protein 68

chr3_+_13946368 0.340 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr5_-_138619702 0.320 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr5_-_138619653 0.319 ENSMUST00000129832.1
Zfp68
zinc finger protein 68
chrX_+_163909132 0.311 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr8_+_12984246 0.289 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr4_+_43381979 0.248 ENSMUST00000035645.5
ENSMUST00000144911.1
Rusc2

RUN and SH3 domain containing 2

chr9_+_57940104 0.246 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr6_-_41636389 0.238 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr14_-_52279238 0.227 ENSMUST00000167116.1
ENSMUST00000100631.4
Rab2b

RAB2B, member RAS oncogene family

chr17_-_32350569 0.219 ENSMUST00000050214.7
Akap8l
A kinase (PRKA) anchor protein 8-like
chr10_+_115384951 0.219 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr4_+_95967322 0.217 ENSMUST00000107083.1
Hook1
hook homolog 1 (Drosophila)
chr14_-_18893623 0.217 ENSMUST00000177259.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr1_+_60409612 0.216 ENSMUST00000052332.8
Abi2
abl-interactor 2
chr9_-_97111117 0.215 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chrX_+_35888808 0.196 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr16_-_62786742 0.181 ENSMUST00000152553.1
ENSMUST00000063089.5
Nsun3

NOL1/NOP2/Sun domain family member 3

chr7_-_24316590 0.178 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr1_+_75436002 0.177 ENSMUST00000131545.1
ENSMUST00000141124.1
Gmppa

GDP-mannose pyrophosphorylase A

chr9_-_117252450 0.174 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr8_+_3393018 0.164 ENSMUST00000004684.6
ENSMUST00000145394.1
Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

chr2_+_83644435 0.160 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr1_+_75435930 0.160 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
Gmppa






GDP-mannose pyrophosphorylase A






chr14_-_18893376 0.159 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr13_-_74482943 0.158 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr5_-_86676346 0.145 ENSMUST00000038448.6
Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr10_+_79669410 0.140 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr5_+_100196611 0.136 ENSMUST00000066813.1
Gm9932
predicted gene 9932
chr6_-_56923927 0.125 ENSMUST00000031793.5
Nt5c3
5'-nucleotidase, cytosolic III
chr7_-_126898249 0.116 ENSMUST00000121532.1
ENSMUST00000032926.5
Tmem219

transmembrane protein 219

chr14_+_79397772 0.107 ENSMUST00000022600.2
Mtrf1
mitochondrial translational release factor 1
chr6_-_149188648 0.100 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
Amn1


antagonist of mitotic exit network 1


chr10_-_86011833 0.095 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr9_-_85749308 0.092 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr11_+_21572221 0.080 ENSMUST00000020568.3
ENSMUST00000131135.1
Wdpcp

WD repeat containing planar cell polarity effector

chr7_+_5080214 0.076 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr14_+_64652524 0.070 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr3_+_76075583 0.067 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr11_+_116532441 0.065 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr8_+_3353415 0.065 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr6_+_3993776 0.060 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_+_144527718 0.055 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr15_+_51877429 0.049 ENSMUST00000137116.2
ENSMUST00000161651.1
ENSMUST00000059599.9
Utp23


UTP23, small subunit (SSU) processome component, homolog (yeast)


chr14_-_55900188 0.047 ENSMUST00000111325.3
Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr17_-_7827289 0.042 ENSMUST00000167580.1
ENSMUST00000169126.1
Fndc1

fibronectin type III domain containing 1

chr5_-_120777628 0.042 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr17_-_6948283 0.037 ENSMUST00000024572.9
Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr10_+_75212065 0.036 ENSMUST00000105421.2
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr2_+_55411790 0.022 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr1_+_171419027 0.020 ENSMUST00000171362.1
Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr16_-_9994921 0.015 ENSMUST00000115835.1
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr8_-_13974715 0.015 ENSMUST00000119182.1
ENSMUST00000062613.4
Tdrp

testis development related protein

chr17_+_7945653 0.015 ENSMUST00000097423.2
Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr13_-_8870999 0.012 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
Wdr37


WD repeat domain 37


chr8_-_84104773 0.009 ENSMUST00000041367.7
Dcaf15
DDB1 and CUL4 associated factor 15
chr4_+_62525369 0.002 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway