Motif ID: Foxd1

Z-value: 1.866


Transcription factors associated with Foxd1:

Gene SymbolEntrez IDGene Name
Foxd1 ENSMUSG00000078302.3 Foxd1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_98354250-0.561.7e-02Click!


Activity profile for motif Foxd1.

activity profile for motif Foxd1


Sorted Z-values histogram for motif Foxd1

Sorted Z-values for motif Foxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144892813 12.230 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893077 9.504 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr13_-_93499803 8.637 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr4_+_144893127 7.952 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr5_+_3928033 7.299 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr11_+_3332426 6.922 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr16_-_22439570 6.127 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr18_+_5593566 5.957 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr12_-_100725028 5.899 ENSMUST00000043599.6
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr8_+_65618009 5.878 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
March1


membrane-associated ring finger (C3HC4) 1


chr6_+_135362931 5.432 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr10_+_60106452 4.910 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr11_+_69095217 4.741 ENSMUST00000101004.2
Per1
period circadian clock 1
chr16_-_22439719 4.729 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr5_+_107437908 4.687 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr11_+_3330781 4.672 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr11_-_101226414 4.435 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
Ezh1


enhancer of zeste homolog 1 (Drosophila)


chr10_-_8518801 4.421 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr16_-_74411292 4.160 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr8_+_20136455 4.021 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chr8_-_84773381 3.976 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr1_+_34005872 3.967 ENSMUST00000182296.1
Dst
dystonin
chr11_+_3330401 3.940 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_+_74619594 3.935 ENSMUST00000100866.2
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr12_+_95695350 3.930 ENSMUST00000110117.1
Flrt2
fibronectin leucine rich transmembrane protein 2
chr7_+_110772604 3.916 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr18_+_69344503 3.910 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr8_-_84978709 3.867 ENSMUST00000064922.5
Junb
Jun-B oncogene
chr5_+_3928267 3.809 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr6_-_39725193 3.808 ENSMUST00000101497.3
Braf
Braf transforming gene
chr13_-_51701041 3.770 ENSMUST00000110042.1
Gm15440
predicted gene 15440
chr1_-_64956731 3.703 ENSMUST00000123225.1
Plekhm3
pleckstrin homology domain containing, family M, member 3
chr3_+_5218516 3.678 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr10_+_29211637 3.673 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr2_+_28641227 3.668 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
Tsc1


tuberous sclerosis 1


chr14_-_55560340 3.660 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr2_+_112265809 3.659 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr7_+_82175156 3.606 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr19_-_28010995 3.541 ENSMUST00000172907.1
ENSMUST00000046898.9
Rfx3

regulatory factor X, 3 (influences HLA class II expression)

chr6_-_5496296 3.532 ENSMUST00000019721.4
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr14_-_18239053 3.506 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr16_-_4880284 3.418 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr1_-_64956807 3.418 ENSMUST00000097713.1
Plekhm3
pleckstrin homology domain containing, family M, member 3
chr16_+_20097554 3.355 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr8_-_46294592 3.289 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr8_+_19682268 3.287 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483

predicted gene 6483

chr19_+_4855129 3.284 ENSMUST00000119694.1
Ctsf
cathepsin F
chr12_-_84450944 3.222 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr1_+_179546303 3.216 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr19_-_28011138 3.201 ENSMUST00000174850.1
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr18_-_34624562 3.182 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr19_+_26750939 3.002 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_5218589 2.996 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr12_+_35047180 2.987 ENSMUST00000048519.9
ENSMUST00000163677.1
Snx13

sorting nexin 13

chr11_-_107348130 2.976 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr13_+_80886095 2.958 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr7_+_113207465 2.849 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr15_-_58214882 2.807 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr3_-_146770218 2.624 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr2_+_181837854 2.617 ENSMUST00000029116.7
ENSMUST00000108754.1
Pcmtd2

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

chr14_-_93888732 2.609 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr11_+_54438188 2.608 ENSMUST00000046835.7
Fnip1
folliculin interacting protein 1
chr11_+_85353156 2.539 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
Bcas3





breast carcinoma amplified sequence 3





chr11_-_102556122 2.506 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr7_+_24907618 2.496 ENSMUST00000151121.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr6_-_13677930 2.419 ENSMUST00000045235.5
B630005N14Rik
RIKEN cDNA B630005N14 gene
chr2_-_73892530 2.329 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
Atf2



activating transcription factor 2



chr3_+_138860489 2.315 ENSMUST00000121826.1
Tspan5
tetraspanin 5
chr15_+_89059712 2.260 ENSMUST00000161372.1
ENSMUST00000162424.1
Panx2

pannexin 2

chr4_-_45012093 2.257 ENSMUST00000131991.1
Zbtb5
zinc finger and BTB domain containing 5
chr9_-_45955170 2.231 ENSMUST00000162072.1
Sidt2
SID1 transmembrane family, member 2
chr8_+_20567716 2.205 ENSMUST00000178995.1
Gm21092
predicted gene, 21092
chr12_+_52699297 2.196 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr10_-_26373956 2.184 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr2_+_19658055 2.182 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr2_-_73312701 2.178 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr3_+_96557950 2.147 ENSMUST00000074519.6
ENSMUST00000049093.7
Txnip

thioredoxin interacting protein

chr8_-_3279606 2.110 ENSMUST00000091291.4
Insr
insulin receptor
chr7_-_44849075 2.106 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr6_-_87809757 2.043 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr11_+_17051818 2.026 ENSMUST00000058159.5
Cnrip1
cannabinoid receptor interacting protein 1
chr17_+_70561739 2.023 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr9_-_107710475 2.021 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_+_31251678 2.021 ENSMUST00000054829.7
ENSMUST00000114570.1
ENSMUST00000075611.7
Krtcap3


keratinocyte associated protein 3


chrX_+_94234921 2.001 ENSMUST00000113908.1
ENSMUST00000113916.3
Klhl15

kelch-like 15

chr7_+_19359740 1.991 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr2_-_104712122 1.983 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr10_-_18234930 1.972 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr19_+_23141183 1.943 ENSMUST00000036884.1
Klf9
Kruppel-like factor 9
chrX_+_94234594 1.942 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr13_-_98815408 1.904 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr7_-_29505447 1.901 ENSMUST00000183096.1
ENSMUST00000085809.4
Sipa1l3

signal-induced proliferation-associated 1 like 3

chr4_+_136357423 1.899 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr9_-_60838200 1.882 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr1_-_183297008 1.875 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr14_-_68655804 1.813 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr2_+_176236860 1.795 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr12_+_38781093 1.761 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr18_+_9707639 1.758 ENSMUST00000040069.8
Colec12
collectin sub-family member 12
chr6_+_92940572 1.746 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr2_-_73892588 1.708 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
Atf2


activating transcription factor 2


chr1_-_97977233 1.708 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr14_+_55560480 1.707 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr3_+_68584154 1.679 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr13_+_104178797 1.657 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr2_+_24976033 1.650 ENSMUST00000045295.7
ENSMUST00000153618.1
ENSMUST00000152777.1
Pnpla7


patatin-like phospholipase domain containing 7


chr6_+_134830145 1.638 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr9_+_45370185 1.632 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chrX_-_7740206 1.628 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr13_-_52929458 1.620 ENSMUST00000123599.1
Auh
AU RNA binding protein/enoyl-coenzyme A hydratase
chr15_+_25752860 1.614 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chrX_+_68678541 1.605 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr12_-_31950210 1.603 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr13_+_118714678 1.588 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chrX_+_7722267 1.570 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr13_+_55209776 1.563 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr5_-_31048014 1.541 ENSMUST00000137223.1
Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr2_-_104028287 1.539 ENSMUST00000056170.3
4931422A03Rik
RIKEN cDNA 4931422A03 gene
chr11_-_106920359 1.534 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr6_+_14901440 1.532 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr13_+_75089826 1.519 ENSMUST00000022075.4
Pcsk1
proprotein convertase subtilisin/kexin type 1
chr11_+_107547925 1.508 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr16_+_24448082 1.488 ENSMUST00000078988.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr12_+_4133394 1.472 ENSMUST00000152065.1
ENSMUST00000127756.1
Adcy3

adenylate cyclase 3

chr11_+_114851142 1.472 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chrX_+_68678624 1.471 ENSMUST00000114656.1
Fmr1
fragile X mental retardation syndrome 1
chr3_+_5218546 1.436 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr11_+_110968016 1.423 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16

potassium inwardly-rectifying channel, subfamily J, member 16

chr14_+_48120841 1.410 ENSMUST00000073150.4
Peli2
pellino 2
chr11_-_107470699 1.405 ENSMUST00000103064.3
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_98741871 1.399 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr12_+_38780817 1.392 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr10_+_21882184 1.386 ENSMUST00000120509.1
Sgk1
serum/glucocorticoid regulated kinase 1
chr2_-_73892619 1.381 ENSMUST00000112007.1
ENSMUST00000112016.2
Atf2

activating transcription factor 2

chr1_-_179546261 1.379 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr3_+_118430299 1.355 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr11_+_43433720 1.344 ENSMUST00000126128.1
ENSMUST00000151880.1
ENSMUST00000020681.3
Slu7


SLU7 splicing factor homolog (S. cerevisiae)


chr11_-_121388186 1.317 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr4_-_45012287 1.277 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
Zbtb5


zinc finger and BTB domain containing 5


chr9_+_110333402 1.276 ENSMUST00000133114.1
ENSMUST00000125759.1
Scap

SREBF chaperone

chr2_-_60125651 1.262 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_-_59549243 1.262 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3



polypyrimidine tract binding protein 3



chr12_-_85270564 1.256 ENSMUST00000019378.6
ENSMUST00000166821.1
Mlh3

mutL homolog 3 (E coli)

chr6_+_134830216 1.231 ENSMUST00000111937.1
Crebl2
cAMP responsive element binding protein-like 2
chr11_+_120232921 1.175 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr6_+_53573364 1.141 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr3_-_144202300 1.134 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr14_+_55560904 1.125 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr6_-_106800051 1.122 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr19_+_30030589 1.101 ENSMUST00000112552.1
Uhrf2
ubiquitin-like, containing PHD and RING finger domains 2
chr18_-_43059418 1.094 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr5_+_25246775 1.087 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr2_+_52072823 1.076 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr5_-_5265224 1.062 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr19_-_7341433 1.045 ENSMUST00000165965.1
ENSMUST00000051711.9
ENSMUST00000169541.1
ENSMUST00000165989.1
Mark2



MAP/microtubule affinity-regulating kinase 2



chr5_+_14025305 1.043 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr5_-_142817387 1.031 ENSMUST00000036253.6
Tnrc18
trinucleotide repeat containing 18
chr10_+_18235030 1.020 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chrX_+_7722214 1.011 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr15_-_79546741 1.011 ENSMUST00000054014.7
Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr6_+_15185203 1.002 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr13_-_52929640 0.998 ENSMUST00000120535.1
ENSMUST00000119311.1
ENSMUST00000021913.9
ENSMUST00000110031.3
Auh



AU RNA binding protein/enoyl-coenzyme A hydratase



chr8_-_119558718 0.984 ENSMUST00000081381.4
ENSMUST00000098362.3
Mbtps1

membrane-bound transcription factor peptidase, site 1

chr14_+_54259227 0.936 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr12_-_31499541 0.921 ENSMUST00000101499.3
ENSMUST00000064240.6
ENSMUST00000085487.5
Cbll1


Casitas B-lineage lymphoma-like 1


chrX_+_68678712 0.918 ENSMUST00000114654.1
ENSMUST00000114655.1
ENSMUST00000114657.2
ENSMUST00000114653.1
Fmr1



fragile X mental retardation syndrome 1



chr19_-_7341848 0.909 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr4_+_133130505 0.874 ENSMUST00000084241.5
ENSMUST00000138831.1
Wasf2

WAS protein family, member 2

chr2_+_112284561 0.874 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr12_-_31950170 0.868 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr1_-_87573825 0.861 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr7_+_126776939 0.861 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr11_+_70214105 0.853 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr15_+_5185700 0.828 ENSMUST00000081640.5
Ttc33
tetratricopeptide repeat domain 33
chrX_+_94234982 0.805 ENSMUST00000096369.3
ENSMUST00000113911.2
Klhl15

kelch-like 15

chr5_-_31047998 0.803 ENSMUST00000114665.1
ENSMUST00000006817.4
Slc5a6

solute carrier family 5 (sodium-dependent vitamin transporter), member 6

chr12_+_71016658 0.791 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr7_-_80402743 0.772 ENSMUST00000122232.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr11_+_90030295 0.758 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr15_+_97784355 0.754 ENSMUST00000117892.1
Slc48a1
solute carrier family 48 (heme transporter), member 1
chr5_-_138171216 0.735 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_+_21372642 0.712 ENSMUST00000035799.5
Fgl2
fibrinogen-like protein 2
chr3_+_32436376 0.706 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr9_-_101198999 0.696 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_176917518 0.680 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr7_-_37772868 0.665 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr10_-_93310963 0.638 ENSMUST00000151153.1
Elk3
ELK3, member of ETS oncogene family
chr15_+_5185519 0.636 ENSMUST00000118193.1
ENSMUST00000022751.8
Ttc33

tetratricopeptide repeat domain 33

chr1_-_54926311 0.625 ENSMUST00000179030.1
ENSMUST00000044359.9
Ankrd44

ankyrin repeat domain 44

chr9_-_45955226 0.614 ENSMUST00000038488.9
Sidt2
SID1 transmembrane family, member 2
chr7_+_16309577 0.614 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr11_-_23497867 0.603 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
Ahsa2


AHA1, activator of heat shock protein ATPase 2


chr3_+_32436151 0.603 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr4_+_155734800 0.583 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr12_-_31950535 0.572 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chrX_+_35888808 0.543 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr19_+_42090422 0.543 ENSMUST00000066778.4
Pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr5_-_142817654 0.536 ENSMUST00000151477.1
Tnrc18
trinucleotide repeat containing 18
chr4_+_32238950 0.533 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr3_-_27153782 0.533 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 29.7 GO:0042572 retinol metabolic process(GO:0042572)
2.2 15.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
2.2 10.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.2 8.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.0 5.9 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.8 5.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.7 6.7 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
1.4 4.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.3 4.0 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
1.2 3.7 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
1.1 3.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
1.1 3.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
1.1 3.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
1.0 3.0 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.9 2.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.9 4.7 GO:0097167 circadian regulation of translation(GO:0097167)
0.9 2.8 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.9 3.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.8 7.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.8 4.7 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.8 3.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 2.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.6 4.5 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.6 11.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.6 2.3 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.6 3.9 GO:0032264 IMP salvage(GO:0032264)
0.5 2.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.5 4.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 1.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 1.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.4 4.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 3.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 1.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 2.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.4 3.0 GO:0033227 dsRNA transport(GO:0033227)
0.4 1.9 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.4 1.5 GO:0008355 olfactory learning(GO:0008355)
0.4 3.9 GO:0042118 endothelial cell activation(GO:0042118)
0.4 3.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 3.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.3 2.0 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 3.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 5.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 1.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 2.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 3.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 5.4 GO:0032060 bleb assembly(GO:0032060)
0.3 1.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3 3.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 0.8 GO:0015886 heme transport(GO:0015886)
0.2 1.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 2.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 3.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 4.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 1.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 4.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.8 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 0.4 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.2 0.8 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.8 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 2.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.5 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.2 1.3 GO:0007144 female meiosis I(GO:0007144)
0.2 4.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 2.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032) negative regulation of macrophage cytokine production(GO:0010936)
0.2 3.3 GO:0001967 suckling behavior(GO:0001967)
0.2 2.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 3.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 0.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 2.0 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 2.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 1.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 2.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.6 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 1.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 1.5 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.7 GO:0001553 luteinization(GO:0001553)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 1.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 2.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 2.3 GO:0002931 response to ischemia(GO:0002931)
0.1 1.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0071455 response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.1 2.7 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 1.0 GO:0010107 potassium ion import(GO:0010107)
0.1 1.7 GO:0009268 response to pH(GO:0009268)
0.1 7.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 2.1 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.9 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0002921 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.4 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 4.4 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 2.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.0 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 2.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.5 GO:0007601 visual perception(GO:0007601)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 2.7 GO:0016042 lipid catabolic process(GO:0016042)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.1 GO:0044307 dendritic branch(GO:0044307)
1.2 3.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.0 4.0 GO:1902737 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
1.0 4.0 GO:0031673 H zone(GO:0031673)
0.7 2.1 GO:0005899 insulin receptor complex(GO:0005899)
0.6 3.9 GO:0035976 AP1 complex(GO:0035976)
0.6 1.9 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.4 1.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.4 2.8 GO:0033391 chromatoid body(GO:0033391)
0.3 1.9 GO:0061689 tricellular tight junction(GO:0061689)
0.3 3.2 GO:0000812 Swr1 complex(GO:0000812)
0.3 3.4 GO:0030057 desmosome(GO:0030057)
0.2 2.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 1.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 2.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 4.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 5.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 6.5 GO:0035861 site of double-strand break(GO:0035861)
0.2 3.0 GO:0071564 npBAF complex(GO:0071564)
0.2 2.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.3 GO:0032300 mismatch repair complex(GO:0032300)
0.1 2.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 4.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 4.2 GO:0030673 axolemma(GO:0030673)
0.1 2.3 GO:0005921 gap junction(GO:0005921)
0.1 5.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.8 GO:0005581 collagen trimer(GO:0005581)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 3.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 13.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 7.7 GO:0016607 nuclear speck(GO:0016607)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 7.4 GO:0031252 cell leading edge(GO:0031252)
0.0 5.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 7.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.6 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
4.2 29.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.0 3.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.9 3.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.8 2.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.8 4.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.7 3.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 8.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 4.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6 4.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 13.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.6 4.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.6 1.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.6 3.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 2.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.5 5.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 1.5 GO:0005118 sevenless binding(GO:0005118)
0.5 4.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 1.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.4 3.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 2.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 6.0 GO:0045499 chemorepellent activity(GO:0045499)
0.4 4.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 3.2 GO:0071253 connexin binding(GO:0071253)
0.3 1.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.3 2.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 1.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.3 2.3 GO:0005243 gap junction channel activity(GO:0005243)
0.3 2.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 2.3 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.2 2.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 1.8 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 0.5 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 3.6 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 3.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 3.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 6.0 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 3.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105) transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 5.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.0 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 1.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 3.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 3.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 12.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 7.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.0 GO:0051117 ATPase binding(GO:0051117)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.8 GO:0000975 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.0 2.7 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 37.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 7.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.3 7.9 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.3 10.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.3 5.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 3.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.1 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 3.9 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 3.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.4 PID_FOXO_PATHWAY FoxO family signaling
0.1 2.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 6.0 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 1.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 15.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 8.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 1.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.8 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 2.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 2.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID_CMYB_PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.1 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.3 2.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 3.7 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 5.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 3.5 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 1.5 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 3.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.2 3.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 3.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 7.9 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.1 1.6 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 5.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 4.2 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.1 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 4.4 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 1.0 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 2.3 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.1 1.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 3.3 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.3 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.4 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.1 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs