Motif ID: Tfap4

Z-value: 1.565


Transcription factors associated with Tfap4:

Gene SymbolEntrez IDGene Name
Tfap4 ENSMUSG00000005718.7 Tfap4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap4mm10_v2_chr16_-_4559720_4559747-0.165.2e-01Click!


Activity profile for motif Tfap4.

activity profile for motif Tfap4


Sorted Z-values histogram for motif Tfap4

Sorted Z-values for motif Tfap4



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_91269759 10.563 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr15_-_66812593 9.244 ENSMUST00000100572.3
Sla
src-like adaptor
chr9_-_40346290 7.928 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr4_+_119814495 6.815 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr6_-_136171722 6.270 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr4_+_48045144 5.485 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr7_-_120202104 5.299 ENSMUST00000033198.5
Crym
crystallin, mu
chr2_-_52335134 5.135 ENSMUST00000075301.3
Neb
nebulin
chr2_+_170731807 4.580 ENSMUST00000029075.4
Dok5
docking protein 5
chr6_-_58907120 4.476 ENSMUST00000059539.3
Nap1l5
nucleosome assembly protein 1-like 5
chr2_+_37516618 4.355 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr16_+_43510267 4.161 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr8_+_66386292 4.084 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr13_+_29014399 3.994 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr15_-_71727815 3.955 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr8_-_115707778 3.806 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr7_+_144284385 3.743 ENSMUST00000097929.2
Shank2
SH3/ankyrin domain gene 2
chr18_-_23041641 3.303 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr10_+_69785507 3.238 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chr13_+_54949388 3.202 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr5_-_89883321 3.124 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr8_+_12984246 2.862 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr19_-_5510467 2.786 ENSMUST00000070172.4
Snx32
sorting nexin 32
chr1_-_79761752 2.776 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
Wdfy1






WD repeat and FYVE domain containing 1






chr13_-_45964964 2.746 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1


chr1_-_134332928 2.696 ENSMUST00000168515.1
Ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_+_87327044 2.634 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr14_-_45219364 2.632 ENSMUST00000022377.4
ENSMUST00000143609.1
ENSMUST00000139526.1
Txndc16


thioredoxin domain containing 16


chr14_+_45219993 2.533 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr2_-_5063996 2.486 ENSMUST00000114996.1
Optn
optineurin
chr6_+_90465287 2.453 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr15_-_102722120 2.416 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr11_-_75454656 2.409 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr3_-_84220853 2.394 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr1_+_127306706 2.390 ENSMUST00000171405.1
Mgat5
mannoside acetylglucosaminyltransferase 5
chr6_+_8259379 2.266 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr3_+_90537242 2.255 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr15_-_99528017 2.238 ENSMUST00000023750.7
Faim2
Fas apoptotic inhibitory molecule 2
chr3_-_88456397 2.101 ENSMUST00000141471.1
ENSMUST00000123753.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr11_+_85353156 2.098 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
Bcas3





breast carcinoma amplified sequence 3





chr9_-_21037775 2.087 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr9_-_114933811 2.053 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr11_+_77348272 1.972 ENSMUST00000181283.1
Ssh2
slingshot homolog 2 (Drosophila)
chr15_+_80287234 1.958 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr8_+_9864251 1.954 ENSMUST00000088080.2
Gm10217
predicted gene 10217
chr15_-_102722150 1.953 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr2_-_5063932 1.942 ENSMUST00000027986.4
Optn
optineurin
chr3_+_90537306 1.891 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr9_-_24503127 1.860 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr19_+_26749726 1.836 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_14514918 1.826 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr9_-_104262900 1.823 ENSMUST00000035170.6
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr10_+_128270546 1.801 ENSMUST00000105238.3
ENSMUST00000085708.2
Stat2

signal transducer and activator of transcription 2

chr3_+_5218516 1.786 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr19_+_45047557 1.784 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
Sfxn3


sideroflexin 3


chr9_+_57072024 1.774 ENSMUST00000169879.1
Sin3a
transcriptional regulator, SIN3A (yeast)
chr1_+_87327008 1.761 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr2_-_77170592 1.754 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr7_-_97417730 1.738 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr9_+_50752758 1.727 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr2_-_122702615 1.647 ENSMUST00000005952.4
ENSMUST00000099457.3
Slc30a4

solute carrier family 30 (zinc transporter), member 4

chr1_-_59237093 1.597 ENSMUST00000163058.1
ENSMUST00000027178.6
Als2

amyotrophic lateral sclerosis 2 (juvenile)

chr9_+_45370185 1.590 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr4_-_11981265 1.565 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr13_+_24638636 1.565 ENSMUST00000110384.2
ENSMUST00000058009.9
ENSMUST00000038477.6
Fam65b


family with sequence similarity 65, member B


chr9_-_50693799 1.539 ENSMUST00000120622.1
Dixdc1
DIX domain containing 1
chr11_+_110968016 1.524 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16

potassium inwardly-rectifying channel, subfamily J, member 16

chr19_+_4510472 1.522 ENSMUST00000068004.6
Pcx
pyruvate carboxylase
chr10_+_80300997 1.473 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr3_+_5218589 1.422 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr18_-_10610346 1.404 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr5_+_90759299 1.391 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr10_+_79997463 1.385 ENSMUST00000171637.1
ENSMUST00000043866.7
Abca7

ATP-binding cassette, sub-family A (ABC1), member 7

chr5_-_73191848 1.377 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr14_+_123659971 1.368 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr2_-_45117349 1.329 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr16_+_14705832 1.321 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr9_-_78587968 1.293 ENSMUST00000117645.1
ENSMUST00000119213.1
ENSMUST00000052441.5
Slc17a5


solute carrier family 17 (anion/sugar transporter), member 5


chr2_-_74579379 1.281 ENSMUST00000130586.1
Lnp
limb and neural patterns
chr11_-_78497458 1.260 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr15_-_100599983 1.246 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr5_+_111733924 1.229 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr11_-_120643643 1.206 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr9_-_39604124 1.182 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chrX_+_101449078 1.177 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr18_+_38296805 1.163 ENSMUST00000171461.1
Rnf14
ring finger protein 14
chr4_+_123016590 1.129 ENSMUST00000102649.3
Trit1
tRNA isopentenyltransferase 1
chr2_+_48949495 1.121 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr5_-_147725988 1.120 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chrX_+_93675088 1.086 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr13_-_117025505 1.076 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr6_-_115251839 1.074 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr4_-_156228540 1.063 ENSMUST00000105571.2
Plekhn1
pleckstrin homology domain containing, family N member 1
chrX_+_134404780 1.054 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr12_-_86884808 1.044 ENSMUST00000038422.6
Irf2bpl
interferon regulatory factor 2 binding protein-like
chr8_+_104591464 1.043 ENSMUST00000059588.6
Pdp2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr18_-_61536522 1.035 ENSMUST00000171629.1
Arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr1_-_97977233 1.021 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr2_+_155382186 1.018 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr1_-_9748376 1.011 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr13_-_97747399 1.005 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_-_8871751 1.005 ENSMUST00000175958.1
Wdr37
WD repeat domain 37
chr11_+_70764209 0.999 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr11_+_69059750 0.993 ENSMUST00000051888.2
2310047M10Rik
RIKEN cDNA 2310047M10 gene
chr13_+_93304940 0.989 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr10_+_39420009 0.941 ENSMUST00000157009.1
Fyn
Fyn proto-oncogene
chr15_+_98708187 0.939 ENSMUST00000003444.4
Ccdc65
coiled-coil domain containing 65
chr11_-_107716517 0.918 ENSMUST00000021065.5
Cacng1
calcium channel, voltage-dependent, gamma subunit 1
chr9_+_59589288 0.916 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr11_+_97362396 0.908 ENSMUST00000045540.3
Socs7
suppressor of cytokine signaling 7
chr2_-_73580288 0.906 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr11_-_68871848 0.903 ENSMUST00000101017.2
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr19_+_60811574 0.878 ENSMUST00000128357.1
ENSMUST00000119633.1
ENSMUST00000025957.8
Fam45a


family with sequence similarity 45, member A


chr15_-_3995708 0.874 ENSMUST00000046633.8
AW549877
expressed sequence AW549877
chr13_-_47014814 0.863 ENSMUST00000052747.2
Nhlrc1
NHL repeat containing 1
chr10_-_102490418 0.840 ENSMUST00000020040.3
Nts
neurotensin
chr13_+_44731281 0.837 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chrX_-_36645359 0.836 ENSMUST00000051906.6
Akap17b
A kinase (PRKA) anchor protein 17B
chr10_+_24149291 0.819 ENSMUST00000020174.5
Stx7
syntaxin 7
chr2_-_74578875 0.808 ENSMUST00000134168.1
ENSMUST00000111993.2
ENSMUST00000064503.6
Lnp


limb and neural patterns


chr18_+_65800543 0.803 ENSMUST00000025394.6
ENSMUST00000153193.1
Sec11c

SEC11 homolog C (S. cerevisiae)

chr3_+_118430299 0.803 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr9_+_74976096 0.789 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr5_+_91517615 0.783 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr8_+_3500451 0.776 ENSMUST00000004683.6
ENSMUST00000160338.1
Mcoln1

mucolipin 1

chr18_+_38296635 0.775 ENSMUST00000072376.5
ENSMUST00000170811.1
Rnf14

ring finger protein 14

chr2_-_75938407 0.771 ENSMUST00000099996.3
Ttc30b
tetratricopeptide repeat domain 30B
chr19_-_45046614 0.770 ENSMUST00000145391.1
Pdzd7
PDZ domain containing 7
chr19_-_42202150 0.765 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr2_-_104712122 0.757 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr8_+_22060712 0.742 ENSMUST00000072572.6
ENSMUST00000110737.2
ENSMUST00000131624.1
Alg11


asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)


chr13_+_118714678 0.720 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr5_+_139791513 0.718 ENSMUST00000018287.3
Mafk
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
chr11_+_68691906 0.714 ENSMUST00000102611.3
Myh10
myosin, heavy polypeptide 10, non-muscle
chr17_+_29679247 0.703 ENSMUST00000129864.1
Cmtr1
cap methyltransferase 1
chr16_+_17451981 0.700 ENSMUST00000006293.3
Crkl
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr12_-_81333129 0.699 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr5_-_121502980 0.697 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr11_-_116086929 0.695 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr6_+_126939957 0.692 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr14_+_20707548 0.685 ENSMUST00000022358.7
Zswim8
zinc finger SWIM-type containing 8
chr4_-_134704235 0.671 ENSMUST00000054096.6
ENSMUST00000038628.3
Man1c1

mannosidase, alpha, class 1C, member 1

chr4_+_120854786 0.669 ENSMUST00000071093.2
Rims3
regulating synaptic membrane exocytosis 3
chr16_-_89818338 0.661 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chr7_+_107567445 0.660 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr4_-_43040279 0.651 ENSMUST00000107958.1
ENSMUST00000107959.1
ENSMUST00000152846.1
Fam214b


family with sequence similarity 214, member B


chr9_-_57147034 0.647 ENSMUST00000034842.4
Neil1
nei endonuclease VIII-like 1 (E. coli)
chr19_-_8929323 0.633 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr5_-_131538687 0.617 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr3_+_5218546 0.615 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr10_-_80742211 0.602 ENSMUST00000020420.7
Ap3d1
adaptor-related protein complex 3, delta 1 subunit
chrX_+_48108912 0.601 ENSMUST00000114998.1
ENSMUST00000115000.3
Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

chr2_-_28840274 0.598 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4

general transcription factor IIIC, polypeptide 4

chr7_-_141435327 0.593 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr7_-_127895578 0.580 ENSMUST00000033074.6
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr2_+_119288725 0.566 ENSMUST00000037280.4
Vps18
vacuolar protein sorting 18 (yeast)
chr15_-_97767798 0.565 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr19_-_4397052 0.563 ENSMUST00000075856.4
Kdm2a
lysine (K)-specific demethylase 2A
chr3_+_95434386 0.562 ENSMUST00000102749.4
ENSMUST00000090804.5
ENSMUST00000107161.1
ENSMUST00000107160.1
ENSMUST00000015666.10
Arnt




aryl hydrocarbon receptor nuclear translocator




chr8_+_121590361 0.555 ENSMUST00000034270.10
ENSMUST00000181948.1
Map1lc3b

microtubule-associated protein 1 light chain 3 beta

chr15_-_82912134 0.551 ENSMUST00000048966.5
ENSMUST00000109510.2
Tcf20

transcription factor 20

chr4_+_129136948 0.537 ENSMUST00000102600.3
Fndc5
fibronectin type III domain containing 5
chr6_-_142702259 0.534 ENSMUST00000073173.5
ENSMUST00000111771.1
ENSMUST00000087527.4
ENSMUST00000100827.2
Abcc9



ATP-binding cassette, sub-family C (CFTR/MRP), member 9



chr17_+_47688992 0.497 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr3_-_51560816 0.492 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr6_-_97179100 0.492 ENSMUST00000095664.3
Tmf1
TATA element modulatory factor 1
chr11_-_30268169 0.489 ENSMUST00000006629.7
Sptbn1
spectrin beta, non-erythrocytic 1
chr17_+_45734506 0.487 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr7_+_16098458 0.486 ENSMUST00000006181.6
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr18_+_57468478 0.464 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr5_+_134099704 0.444 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr9_+_108296853 0.432 ENSMUST00000035230.5
Amt
aminomethyltransferase
chr10_+_60277627 0.423 ENSMUST00000105465.1
ENSMUST00000177779.1
ENSMUST00000179238.1
ENSMUST00000004316.8
Psap



prosaposin



chr3_+_9250602 0.422 ENSMUST00000155203.1
Zbtb10
zinc finger and BTB domain containing 10
chr5_-_73647713 0.408 ENSMUST00000081170.7
Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr11_-_119086221 0.403 ENSMUST00000026665.7
Cbx4
chromobox 4
chr5_-_28210022 0.398 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr4_-_136021722 0.394 ENSMUST00000030427.5
Tceb3
transcription elongation factor B (SIII), polypeptide 3
chr18_+_60293372 0.382 ENSMUST00000171297.1
F830016B08Rik
RIKEN cDNA F830016B08 gene
chrX_+_151522352 0.362 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chr6_-_92481343 0.354 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr11_+_77801325 0.349 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
Myo18a




myosin XVIIIA




chr7_-_141902361 0.346 ENSMUST00000055819.6
ENSMUST00000130439.1
ENSMUST00000001950.5
Tollip


toll interacting protein


chr4_+_43632185 0.339 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr4_-_139310665 0.335 ENSMUST00000172747.1
ENSMUST00000105801.2
ENSMUST00000053862.5
Pqlc2


PQ loop repeat containing 2


chr4_+_74251928 0.325 ENSMUST00000030102.5
Kdm4c
lysine (K)-specific demethylase 4C
chr13_+_93308006 0.324 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr18_-_10610048 0.322 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr11_+_82952095 0.317 ENSMUST00000108158.2
ENSMUST00000067443.2
Slfn5

schlafen 5

chr8_+_83165348 0.311 ENSMUST00000034145.4
Tbc1d9
TBC1 domain family, member 9
chr5_+_72914264 0.277 ENSMUST00000144843.1
Slain2
SLAIN motif family, member 2
chr5_+_34999111 0.269 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr11_-_50431101 0.259 ENSMUST00000020643.3
Rufy1
RUN and FYVE domain containing 1
chr9_-_105131775 0.241 ENSMUST00000035179.6
Nudt16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr9_+_63602650 0.240 ENSMUST00000041551.7
Aagab
alpha- and gamma-adaptin binding protein
chr18_-_10610124 0.236 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr5_+_72914554 0.232 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr5_+_117357274 0.222 ENSMUST00000031309.9
Wsb2
WD repeat and SOCS box-containing 2
chr7_+_30712209 0.203 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr2_-_160367057 0.197 ENSMUST00000099126.3
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.6 6.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.1 4.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.1 5.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.7 2.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.6 3.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.6 1.9 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 1.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.6 1.8 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.5 1.5 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.5 1.4 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.4 1.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.4 3.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 2.8 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.4 2.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.4 2.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 1.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 1.0 GO:0046543 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.3 3.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 4.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 1.4 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.3 1.8 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.3 0.8 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 2.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 0.7 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 0.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 0.9 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 0.7 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 4.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.7 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 1.0 GO:0090168 Golgi reassembly(GO:0090168)
0.2 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 1.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 1.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 0.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 1.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 1.2 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 0.5 GO:2000836 positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845)
0.2 0.8 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 4.7 GO:0071625 vocalization behavior(GO:0071625)
0.2 1.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 4.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.7 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 1.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.5 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 2.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 9.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 3.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.2 GO:0021681 cerebellar granular layer development(GO:0021681)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 5.1 GO:0045214 sarcomere organization(GO:0045214)
0.1 1.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 2.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.7 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 4.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.1 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.2 GO:0021546 rhombomere development(GO:0021546)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 4.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.9 GO:0048680 membrane disassembly(GO:0030397) positive regulation of axon regeneration(GO:0048680) nuclear envelope disassembly(GO:0051081)
0.1 0.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.0 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.3 GO:0080144 amino acid homeostasis(GO:0080144)
0.1 1.8 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.6 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 6.0 GO:0048663 neuron fate commitment(GO:0048663)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 5.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.9 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 2.0 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 1.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.1 GO:1905075 negative regulation of macrophage cytokine production(GO:0010936) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1 1.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 1.8 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.1 2.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.9 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 1.7 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.2 GO:0010155 regulation of proton transport(GO:0010155)
0.0 1.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 1.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 4.2 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 4.1 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 4.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.9 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.3 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 2.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 1.3 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.6 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 2.4 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.5 GO:0008542 visual learning(GO:0008542)
0.0 1.3 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.8 GO:0055072 iron ion homeostasis(GO:0055072)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.4 6.3 GO:0043083 synaptic cleft(GO:0043083)
0.4 3.7 GO:0005883 neurofilament(GO:0005883)
0.4 2.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 1.7 GO:0097512 cardiac myofibril(GO:0097512)
0.3 4.4 GO:1990635 proximal dendrite(GO:1990635)
0.3 1.8 GO:0071203 WASH complex(GO:0071203)
0.2 0.6 GO:0098830 presynaptic endosome(GO:0098830)
0.2 0.8 GO:0002141 stereocilia ankle link(GO:0002141)
0.2 2.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 4.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 0.8 GO:0070820 tertiary granule(GO:0070820)
0.2 3.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.7 GO:0097513 myosin II filament(GO:0097513)
0.1 0.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 1.5 GO:0031258 catenin complex(GO:0016342) lamellipodium membrane(GO:0031258)
0.1 2.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0008091 spectrin(GO:0008091) cuticular plate(GO:0032437)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.8 GO:0071564 npBAF complex(GO:0071564)
0.1 3.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 12.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.1 GO:0010369 chromocenter(GO:0010369)
0.1 2.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 5.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 3.5 GO:0005770 late endosome(GO:0005770)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 7.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.3 GO:0043197 dendritic spine(GO:0043197)
0.0 2.0 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0042175 endoplasmic reticulum membrane(GO:0005789) nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.8 6.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.7 2.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.6 5.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 3.2 GO:0005042 netrin receptor activity(GO:0005042)
0.5 4.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.5 2.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 2.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.5 1.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 2.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 5.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 2.7 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.5 GO:0009374 biotin binding(GO:0009374)
0.2 0.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 9.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.9 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 1.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 4.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.7 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 4.1 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 4.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 4.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 5.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 3.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.6 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.8 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.3 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089) nickel cation binding(GO:0016151)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0048038 quinone binding(GO:0048038)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 5.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 7.7 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 4.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.1 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 3.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.9 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 1.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.9 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 2.2 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 3.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 4.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 2.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_RB_1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 3.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.8 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 3.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.1 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.9 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.6 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.5 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 3.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.0 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling