Motif ID: Esrrb_Esrra
Z-value: 1.242


Transcription factors associated with Esrrb_Esrra:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Esrra | ENSMUSG00000024955.7 | Esrra |
Esrrb | ENSMUSG00000021255.11 | Esrrb |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Esrra | mm10_v2_chr19_-_6921753_6921803 | -0.33 | 1.9e-01 | Click! |
Esrrb | mm10_v2_chr12_+_86421628_86421662 | 0.21 | 3.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.8 | 4.7 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.6 | 2.5 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.6 | 1.7 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.5 | 1.6 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.5 | 5.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.5 | 4.8 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.5 | 1.4 | GO:0086047 | membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) |
0.4 | 1.7 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
0.4 | 1.9 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.4 | 1.1 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
0.4 | 1.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.4 | 1.1 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
0.3 | 1.7 | GO:0019244 | lactate biosynthetic process from pyruvate(GO:0019244) |
0.3 | 1.7 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.3 | 1.0 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
0.3 | 2.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.3 | 0.9 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.3 | 1.2 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.3 | 0.9 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) |
0.3 | 0.8 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.3 | 6.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.3 | 0.8 | GO:0009814 | defense response, incompatible interaction(GO:0009814) |
0.3 | 0.8 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
0.3 | 1.8 | GO:0035902 | response to immobilization stress(GO:0035902) |
0.3 | 10.6 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.2 | 1.5 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.2 | 0.7 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.2 | 0.7 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.2 | 1.4 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.2 | 0.7 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.2 | 0.7 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.2 | 2.4 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.2 | 0.7 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.2 | 1.7 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.2 | 1.3 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.2 | 0.8 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.2 | 1.4 | GO:0009249 | protein lipoylation(GO:0009249) |
0.2 | 0.6 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.2 | 0.6 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.2 | 1.0 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.2 | 0.4 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
0.2 | 0.6 | GO:0060166 | olfactory pit development(GO:0060166) |
0.2 | 0.9 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.2 | 0.5 | GO:0042713 | sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455) |
0.2 | 1.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.2 | 0.5 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.2 | 2.2 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.2 | 1.4 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.2 | 0.5 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.2 | 0.7 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.2 | 0.7 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.2 | 0.3 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
0.2 | 0.8 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.2 | 2.3 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
0.2 | 0.5 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
0.1 | 0.4 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.1 | 0.7 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
0.1 | 1.5 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.1 | 0.3 | GO:0019046 | release from viral latency(GO:0019046) |
0.1 | 0.1 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.1 | 0.8 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.1 | 1.0 | GO:0090234 | cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234) |
0.1 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
0.1 | 0.8 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.1 | 0.4 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.1 | 0.9 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
0.1 | 0.5 | GO:1990379 | lipid transport across blood brain barrier(GO:1990379) |
0.1 | 0.7 | GO:0051665 | membrane raft localization(GO:0051665) |
0.1 | 2.6 | GO:0007614 | short-term memory(GO:0007614) |
0.1 | 0.4 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.1 | 0.6 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.1 | 1.7 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 0.3 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
0.1 | 0.9 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
0.1 | 0.3 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.1 | 0.5 | GO:0035701 | hematopoietic stem cell migration(GO:0035701) |
0.1 | 0.6 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.1 | 0.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.4 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 0.7 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.1 | 0.8 | GO:0031999 | negative regulation of fatty acid beta-oxidation(GO:0031999) |
0.1 | 0.3 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.1 | 0.5 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.1 | 0.3 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.1 | 0.6 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 0.6 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.1 | 0.3 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.1 | 0.6 | GO:0061198 | fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.1 | 1.4 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.1 | 0.4 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.1 | 2.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.4 | GO:0015744 | succinate transport(GO:0015744) |
0.1 | 0.3 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
0.1 | 2.6 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.1 | 0.7 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.1 | 0.4 | GO:0002082 | regulation of oxidative phosphorylation(GO:0002082) |
0.1 | 0.5 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.1 | 1.0 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
0.1 | 0.5 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.1 | 1.8 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.1 | 0.4 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
0.1 | 0.4 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.1 | 0.3 | GO:0018343 | protein farnesylation(GO:0018343) |
0.1 | 0.9 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.1 | 0.5 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.1 | 0.2 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.1 | 0.8 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.1 | 0.4 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.1 | 0.7 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.1 | 1.4 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 0.5 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 1.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.1 | 1.6 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.1 | 0.2 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
0.1 | 0.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 0.4 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.1 | 0.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 1.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.1 | 0.5 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
0.1 | 0.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.1 | 0.2 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
0.1 | 0.9 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.1 | 0.4 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
0.1 | 0.6 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
0.1 | 0.3 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.1 | 3.1 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.1 | 0.8 | GO:0015732 | prostaglandin transport(GO:0015732) |
0.1 | 0.2 | GO:0030043 | actin filament fragmentation(GO:0030043) |
0.1 | 0.7 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
0.1 | 0.3 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
0.1 | 2.2 | GO:0048713 | regulation of oligodendrocyte differentiation(GO:0048713) |
0.1 | 0.3 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.6 | GO:0031639 | plasminogen activation(GO:0031639) |
0.1 | 1.0 | GO:0045116 | protein neddylation(GO:0045116) |
0.1 | 0.2 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.0 | 0.1 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.0 | 3.2 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.5 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.3 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 1.4 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 1.0 | GO:0001990 | regulation of systemic arterial blood pressure by hormone(GO:0001990) |
0.0 | 0.5 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
0.0 | 0.2 | GO:0051012 | microtubule sliding(GO:0051012) |
0.0 | 0.3 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.0 | 2.9 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.0 | 0.6 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.0 | 0.1 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.2 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
0.0 | 0.2 | GO:0034214 | protein hexamerization(GO:0034214) |
0.0 | 1.1 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.2 | GO:0019731 | antibacterial humoral response(GO:0019731) |
0.0 | 0.7 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
0.0 | 0.5 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
0.0 | 0.4 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
0.0 | 0.4 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.0 | 0.1 | GO:0035672 | regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672) |
0.0 | 0.3 | GO:0023021 | termination of signal transduction(GO:0023021) |
0.0 | 0.1 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.0 | 0.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.3 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
0.0 | 0.2 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.0 | 0.3 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.0 | 0.2 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.0 | 0.7 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 0.4 | GO:0002385 | mucosal immune response(GO:0002385) |
0.0 | 0.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.0 | 0.7 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.0 | 0.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.2 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
0.0 | 1.3 | GO:1903078 | positive regulation of protein localization to plasma membrane(GO:1903078) |
0.0 | 0.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
0.0 | 0.1 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
0.0 | 0.6 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
0.0 | 0.7 | GO:0042026 | protein refolding(GO:0042026) |
0.0 | 2.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.0 | 0.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.0 | 1.9 | GO:0007338 | single fertilization(GO:0007338) |
0.0 | 0.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.0 | 0.4 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
0.0 | 0.8 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 1.2 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.6 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.1 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
0.0 | 0.1 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.0 | 0.6 | GO:0001893 | maternal placenta development(GO:0001893) |
0.0 | 1.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 0.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
0.0 | 0.7 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
0.0 | 0.5 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.2 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.9 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
0.0 | 0.1 | GO:1902513 | regulation of organelle transport along microtubule(GO:1902513) |
0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.1 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308) |
0.0 | 0.8 | GO:0045471 | response to ethanol(GO:0045471) |
0.0 | 0.6 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
0.0 | 0.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) choline metabolic process(GO:0019695) |
0.0 | 0.8 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.0 | 0.7 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
0.0 | 0.1 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
0.0 | 0.1 | GO:0046133 | pyrimidine ribonucleoside catabolic process(GO:0046133) |
0.0 | 0.7 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.0 | 0.2 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
0.0 | 0.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.0 | 0.3 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
0.0 | 0.3 | GO:0030262 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262) |
0.0 | 0.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.3 | GO:2000398 | regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398) |
0.0 | 0.9 | GO:0032418 | lysosome localization(GO:0032418) |
0.0 | 0.2 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 1.3 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.2 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.0 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.0 | 0.2 | GO:0032506 | cytokinetic process(GO:0032506) |
0.0 | 0.5 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.0 | 0.2 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
0.0 | 0.2 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
0.0 | 0.1 | GO:0090190 | positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
0.0 | 0.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.0 | 0.1 | GO:0007007 | inner mitochondrial membrane organization(GO:0007007) |
0.0 | 0.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.1 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.0 | 0.6 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.3 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
0.0 | 0.3 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.3 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
0.0 | 0.1 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 7.4 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.5 | 13.1 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.5 | 1.6 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
0.3 | 4.0 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.3 | 2.7 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.3 | 1.2 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.3 | 1.8 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.2 | 12.0 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
0.2 | 1.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.2 | 0.4 | GO:0097444 | spine apparatus(GO:0097444) |
0.2 | 1.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.2 | 2.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.1 | 0.7 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
0.1 | 0.6 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.1 | 0.7 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 0.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.8 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.1 | 1.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 1.8 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.4 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
0.1 | 1.9 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.1 | 0.3 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.1 | 0.3 | GO:0070069 | cytochrome complex(GO:0070069) |
0.1 | 0.8 | GO:0001520 | outer dense fiber(GO:0001520) |
0.1 | 0.4 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
0.1 | 1.0 | GO:0032426 | stereocilium tip(GO:0032426) |
0.1 | 1.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.1 | 0.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.1 | 4.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 0.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.1 | 0.2 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.1 | 1.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.1 | 0.7 | GO:0045298 | tubulin complex(GO:0045298) |
0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.1 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.1 | 0.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.1 | 2.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.4 | GO:0061617 | MICOS complex(GO:0061617) |
0.1 | 1.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 0.4 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 0.6 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 0.5 | GO:0032009 | early phagosome(GO:0032009) |
0.0 | 0.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 0.5 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0031983 | vesicle lumen(GO:0031983) |
0.0 | 0.7 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.4 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.0 | 0.4 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.7 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 10.2 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.3 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.0 | 0.3 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.5 | GO:0098800 | inner mitochondrial membrane protein complex(GO:0098800) |
0.0 | 7.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.3 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.0 | 0.6 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.4 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 2.5 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 0.4 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 1.3 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 0.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.2 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
0.0 | 0.4 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.3 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 0.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.0 | 0.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.0 | 0.6 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 7.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.3 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 1.9 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.3 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.2 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.3 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 0.6 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.0 | 0.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.1 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.0 | 0.5 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.0 | 0.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 3.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 1.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 0.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.5 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 2.1 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.6 | GO:0030118 | clathrin coat(GO:0030118) |
0.0 | 0.1 | GO:0097427 | microtubule bundle(GO:0097427) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.8 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.7 | 3.7 | GO:0043532 | angiostatin binding(GO:0043532) |
0.6 | 4.8 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.6 | 6.0 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.6 | 1.7 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.4 | 6.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.4 | 1.7 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.4 | 1.6 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.4 | 1.2 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
0.4 | 2.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.3 | 7.5 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.3 | 1.7 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.3 | 0.9 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.3 | 2.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.3 | 2.3 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.3 | 0.8 | GO:0016015 | morphogen activity(GO:0016015) |
0.2 | 2.5 | GO:0015266 | protein channel activity(GO:0015266) |
0.2 | 0.7 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.2 | 1.3 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.2 | 1.2 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.2 | 1.0 | GO:0004359 | glutaminase activity(GO:0004359) |
0.2 | 1.4 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.2 | 0.9 | GO:0045340 | mercury ion binding(GO:0045340) |
0.2 | 0.9 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.2 | 0.8 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.2 | 0.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.2 | 4.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.2 | 1.0 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.2 | 1.1 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.2 | 0.6 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.2 | 0.5 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
0.2 | 0.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.2 | 4.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.2 | 0.6 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.2 | 0.5 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
0.2 | 0.5 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.2 | 0.5 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.1 | 0.4 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.1 | 3.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.1 | 0.3 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
0.1 | 0.6 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
0.1 | 1.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.1 | 0.7 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.4 | GO:0003977 | UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977) |
0.1 | 4.0 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.1 | 1.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 0.4 | GO:0030172 | troponin C binding(GO:0030172) |
0.1 | 0.4 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
0.1 | 1.0 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.1 | 0.4 | GO:0015141 | succinate transmembrane transporter activity(GO:0015141) sodium:dicarboxylate symporter activity(GO:0017153) |
0.1 | 0.6 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.1 | 0.8 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
0.1 | 2.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 0.7 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.1 | 0.8 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.1 | 0.3 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.1 | 0.3 | GO:0070052 | collagen V binding(GO:0070052) |
0.1 | 0.7 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.1 | 0.6 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.1 | 1.0 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.8 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.1 | 0.6 | GO:0017040 | ceramidase activity(GO:0017040) |
0.1 | 1.1 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 1.8 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 1.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 0.3 | GO:0019808 | polyamine binding(GO:0019808) |
0.1 | 0.7 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.1 | 0.8 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 0.2 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.1 | 0.4 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 0.4 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.1 | 0.8 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.1 | 0.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.1 | 1.3 | GO:0009055 | electron carrier activity(GO:0009055) |
0.1 | 0.9 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 0.2 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
0.1 | 2.4 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 0.2 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.1 | 1.8 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
0.1 | 0.3 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.1 | 0.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.1 | 0.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 0.7 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.1 | 1.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.5 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.1 | 0.4 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.1 | 1.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.9 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 0.5 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.0 | 0.6 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 2.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 1.3 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
0.0 | 0.7 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.5 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.0 | 1.9 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 0.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.4 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.3 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.2 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 0.3 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.0 | 0.1 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
0.0 | 0.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.0 | 0.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 5.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 0.6 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
0.0 | 0.1 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.0 | 0.1 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
0.0 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 0.3 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.0 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.1 | GO:0004104 | choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.0 | 0.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 0.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.1 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.1 | GO:0004064 | arylesterase activity(GO:0004064) |
0.0 | 1.1 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 1.2 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.0 | 0.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.0 | 0.1 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.5 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 0.4 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
0.0 | 0.3 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.1 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.0 | 0.6 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.1 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
0.0 | 1.5 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.2 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.0 | 0.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 1.0 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.2 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
0.0 | 0.5 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 0.2 | GO:0008106 | alcohol dehydrogenase (NADP+) activity(GO:0008106) |
0.0 | 0.2 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.8 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.2 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
0.0 | 0.1 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 2.0 | GO:0008168 | methyltransferase activity(GO:0008168) |
0.0 | 0.1 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.5 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.3 | GO:0050699 | WW domain binding(GO:0050699) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 0.7 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.2 | 1.9 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 1.8 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 2.8 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 0.2 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.1 | 0.8 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 1.7 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 1.1 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 0.6 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 1.9 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 0.9 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 1.1 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 1.2 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 3.9 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.5 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.3 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 1.2 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 1.2 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 1.2 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.3 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 1.0 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.0 | 0.7 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 0.4 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 0.2 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.6 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 0.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 1.1 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.5 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.1 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
0.0 | 1.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 0.3 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 0.4 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 0.4 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 7.7 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.3 | 23.9 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.2 | 1.7 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.2 | 1.3 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.2 | 7.4 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.1 | 2.3 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 3.0 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 3.6 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.1 | 0.8 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.1 | 0.8 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.1 | 1.1 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.1 | 1.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.1 | 0.4 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 1.8 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 0.9 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.1 | 1.7 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.1 | 1.5 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.1 | 0.6 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 2.1 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.1 | 0.8 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.1 | 1.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.6 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
0.0 | 3.2 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 1.1 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.0 | 0.3 | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK |
0.0 | 0.3 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.0 | 1.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.8 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 1.4 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 0.8 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.3 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.0 | 0.6 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 2.5 | REACTOME_SIGNALING_BY_NOTCH1 | Genes involved in Signaling by NOTCH1 |
0.0 | 0.5 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 0.4 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.0 | 0.4 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.0 | 1.4 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.9 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 0.7 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.2 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.7 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.8 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 0.3 | REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
0.0 | 0.3 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 2.0 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.0 | 0.2 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.9 | REACTOME_TRANSLATION | Genes involved in Translation |
0.0 | 1.1 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.8 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.2 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.2 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 0.4 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.2 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.2 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 0.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.2 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.2 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.6 | REACTOME_RNA_POL_III_TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
0.0 | 1.8 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.5 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.1 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 0.2 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.0 | 0.1 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
0.0 | 0.2 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 0.1 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |