Motif ID: Hoxd11_Cdx1_Hoxc11

Z-value: 0.667

Transcription factors associated with Hoxd11_Cdx1_Hoxc11:

Gene SymbolEntrez IDGene Name
Cdx1 ENSMUSG00000024619.8 Cdx1
Hoxc11 ENSMUSG00000001656.3 Hoxc11
Hoxd11 ENSMUSG00000042499.12 Hoxd11






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd11_Cdx1_Hoxc11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_159737510 3.181 ENSMUST00000111669.3
Tnr
tenascin R
chr13_-_84064772 2.624 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr4_+_144893127 2.225 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr17_+_3397189 2.062 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr17_-_91092715 1.921 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr15_+_81936753 1.867 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr15_+_81936911 1.750 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr4_+_144892813 1.617 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr6_-_13839916 1.477 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr17_+_31433054 1.374 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr9_-_55919605 1.342 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr2_+_32395896 1.253 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr4_+_144893077 1.221 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_+_57455898 1.071 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr1_-_56969864 0.999 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr13_-_101692624 0.973 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr11_+_29463735 0.956 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr10_+_116177351 0.929 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr3_+_62419668 0.924 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr1_-_56969827 0.908 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr6_+_80018877 0.897 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr4_-_64046925 0.893 ENSMUST00000107377.3
Tnc
tenascin C
chr2_-_66410064 0.806 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr3_+_108591279 0.787 ENSMUST00000051145.8
ENSMUST00000139626.1
Wdr47

WD repeat domain 47

chr15_+_100761741 0.774 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr4_-_88033328 0.771 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_+_25306085 0.767 ENSMUST00000119703.1
ENSMUST00000108409.1
Tmem145

transmembrane protein 145

chr10_+_123264076 0.750 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr19_-_45812291 0.727 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr2_+_65930117 0.678 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_+_81077274 0.678 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr18_+_69593361 0.640 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr1_-_72536930 0.628 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr7_-_134232005 0.597 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr18_-_42899470 0.588 ENSMUST00000120632.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_+_19103022 0.587 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr5_-_62765618 0.570 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_29906087 0.566 ENSMUST00000053521.8
Zfp27
zinc finger protein 27
chr10_+_69787431 0.554 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr1_+_81077204 0.548 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr5_-_25100624 0.542 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr16_+_11405648 0.531 ENSMUST00000096273.2
Snx29
sorting nexin 29
chr13_-_23622502 0.518 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr7_-_73537621 0.502 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr10_-_25200110 0.495 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr6_-_97617536 0.489 ENSMUST00000113355.2
Frmd4b
FERM domain containing 4B
chrX_-_12673540 0.471 ENSMUST00000060108.6
1810030O07Rik
RIKEN cDNA 1810030O07 gene
chr3_+_103575275 0.465 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr5_+_107497718 0.457 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr4_+_31964081 0.448 ENSMUST00000037607.4
ENSMUST00000080933.6
ENSMUST00000108183.1
ENSMUST00000108184.2
Map3k7



mitogen-activated protein kinase kinase kinase 7



chr2_+_178141920 0.434 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr16_-_4880284 0.431 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr17_-_90455872 0.426 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr7_-_142661858 0.425 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr5_+_150259922 0.420 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr6_-_12749193 0.420 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr4_-_11981265 0.408 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chrX_-_162565514 0.403 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr2_-_45112890 0.402 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr6_+_8259288 0.396 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr5_-_62766153 0.394 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_95579463 0.382 ENSMUST00000150830.1
ENSMUST00000134012.2
Fggy

FGGY carbohydrate kinase domain containing

chr5_+_107497762 0.376 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr4_+_102254739 0.375 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_+_180109192 0.375 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr3_+_103575231 0.374 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr13_-_99344652 0.368 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr5_-_73256555 0.357 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr7_-_141435327 0.350 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr18_+_36939178 0.348 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr10_+_119992916 0.343 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr1_-_175491130 0.337 ENSMUST00000027812.5
Rgs7
regulator of G protein signaling 7
chrX_+_150547375 0.330 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr7_+_4922251 0.328 ENSMUST00000047309.5
Nat14
N-acetyltransferase 14
chr16_-_89508313 0.323 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr7_-_134232125 0.316 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr16_+_42907563 0.311 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr19_+_60755947 0.305 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr16_+_32877775 0.303 ENSMUST00000023489.4
ENSMUST00000171325.1
Fyttd1

forty-two-three domain containing 1

chr3_+_66985947 0.299 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr14_+_76504185 0.298 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr11_-_79504078 0.296 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr1_-_176807124 0.285 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr9_-_39604124 0.278 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr2_-_24048857 0.269 ENSMUST00000114497.1
Hnmt
histamine N-methyltransferase
chr12_+_55836365 0.264 ENSMUST00000059250.6
Brms1l
breast cancer metastasis-suppressor 1-like
chrX_-_43274786 0.263 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr1_-_155099630 0.258 ENSMUST00000055322.4
Ier5
immediate early response 5
chr5_-_24030649 0.257 ENSMUST00000030849.6
Fam126a
family with sequence similarity 126, member A
chr1_+_153874335 0.255 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr1_-_37496095 0.251 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr11_-_109298066 0.247 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr17_-_35910032 0.245 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chrX_-_75578188 0.235 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr9_-_101198999 0.235 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr7_+_103550368 0.233 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr18_-_42899294 0.231 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_+_89454769 0.226 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr11_-_109298090 0.220 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr16_-_35769356 0.220 ENSMUST00000023554.8
Dirc2
disrupted in renal carcinoma 2 (human)
chr18_-_37020679 0.219 ENSMUST00000097612.2
Gm10545
predicted gene 10545
chr10_-_30655859 0.219 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr16_-_91728599 0.215 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr7_-_141434532 0.213 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr4_-_47057296 0.213 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr16_-_32877723 0.212 ENSMUST00000119810.1
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr16_-_91728701 0.207 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr9_-_44799179 0.207 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr8_-_105943382 0.203 ENSMUST00000038896.7
Lcat
lecithin cholesterol acyltransferase
chr19_-_50678642 0.203 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr2_-_33086366 0.203 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr11_-_109298121 0.192 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr14_+_74640840 0.189 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr14_+_66868850 0.189 ENSMUST00000100453.1
Gm5464
predicted gene 5464
chr3_-_87768932 0.188 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr12_+_105453831 0.186 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chrX_+_20364481 0.186 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr1_-_157256682 0.185 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr4_+_136143497 0.178 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr2_+_29965560 0.177 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr6_-_144209558 0.173 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr8_+_25720054 0.173 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chrX_-_105928547 0.165 ENSMUST00000101305.2
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr14_+_20674311 0.165 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr10_+_26822560 0.159 ENSMUST00000135866.1
Arhgap18
Rho GTPase activating protein 18
chr3_+_66985647 0.158 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chrX_+_36195938 0.158 ENSMUST00000048067.3
Zcchc12
zinc finger, CCHC domain containing 12
chr19_-_6067785 0.157 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chr10_+_90071095 0.156 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_+_97798995 0.154 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr3_-_88459047 0.151 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr10_-_105574435 0.146 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chrX_+_36195904 0.145 ENSMUST00000115258.2
Zcchc12
zinc finger, CCHC domain containing 12
chr4_+_136284658 0.141 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr2_-_79908428 0.141 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr3_+_76074270 0.139 ENSMUST00000038364.8
Fstl5
follistatin-like 5
chr7_-_27181149 0.130 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr3_-_88458876 0.129 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr2_+_73271925 0.123 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chrX_+_36195950 0.121 ENSMUST00000115257.1
Zcchc12
zinc finger, CCHC domain containing 12
chr6_-_122340499 0.120 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr4_+_136284708 0.119 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr2_-_27463994 0.118 ENSMUST00000164296.1
Brd3
bromodomain containing 3
chr1_+_59256906 0.118 ENSMUST00000160662.1
ENSMUST00000114248.2
Cdk15

cyclin-dependent kinase 15

chrX_+_36195968 0.113 ENSMUST00000115256.1
Zcchc12
zinc finger, CCHC domain containing 12
chr3_+_88965812 0.112 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr19_-_46395722 0.111 ENSMUST00000040270.4
Actr1a
ARP1 actin-related protein 1A, centractin alpha
chr1_-_152625212 0.110 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr4_+_59035088 0.109 ENSMUST00000041160.6
Gng10
guanine nucleotide binding protein (G protein), gamma 10
chr4_+_62286441 0.109 ENSMUST00000084530.2
Slc31a2
solute carrier family 31, member 2
chr7_-_31051431 0.108 ENSMUST00000073892.4
Fxyd7
FXYD domain-containing ion transport regulator 7
chr8_+_40307458 0.108 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chr4_-_14826582 0.106 ENSMUST00000117268.1
Otud6b
OTU domain containing 6B
chr6_-_144209448 0.099 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr6_+_95117740 0.097 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr13_-_56895737 0.096 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr4_+_20008357 0.095 ENSMUST00000117632.1
ENSMUST00000098244.1
Ttpa

tocopherol (alpha) transfer protein

chr11_+_115933282 0.092 ENSMUST00000140991.1
Sap30bp
SAP30 binding protein
chr2_-_31845925 0.091 ENSMUST00000028188.7
Fibcd1
fibrinogen C domain containing 1
chr2_+_116900152 0.091 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr6_-_144209471 0.084 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr11_-_77607812 0.083 ENSMUST00000058496.7
Taok1
TAO kinase 1
chr15_-_82047579 0.082 ENSMUST00000166578.1
ENSMUST00000080622.7
Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr3_-_89349968 0.082 ENSMUST00000074582.6
ENSMUST00000107448.2
ENSMUST00000029676.5
Adam15


a disintegrin and metallopeptidase domain 15 (metargidin)


chr13_+_104109752 0.080 ENSMUST00000160322.1
ENSMUST00000159574.1
Sgtb

small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta

chr4_+_108479081 0.073 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr3_+_10088173 0.072 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr2_-_79908389 0.072 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr6_-_112947246 0.071 ENSMUST00000088373.4
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr18_-_3281712 0.071 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
Crem



cAMP responsive element modulator



chr3_-_89349939 0.068 ENSMUST00000107446.1
Adam15
a disintegrin and metallopeptidase domain 15 (metargidin)
chr16_-_55838827 0.067 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr11_-_103267405 0.060 ENSMUST00000021324.2
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr7_+_45062429 0.059 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
Nosip



nitric oxide synthase interacting protein



chr8_-_83458386 0.058 ENSMUST00000081506.3
Scoc
short coiled-coil protein
chr1_+_137928100 0.058 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr6_-_8259098 0.056 ENSMUST00000012627.4
Rpa3
replication protein A3
chr8_+_121116163 0.055 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr2_+_119208975 0.052 ENSMUST00000102519.4
Zfyve19
zinc finger, FYVE domain containing 19
chr5_+_32611171 0.051 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr10_-_81364846 0.051 ENSMUST00000131736.1
4930404N11Rik
RIKEN cDNA 4930404N11 gene
chr5_+_33018816 0.050 ENSMUST00000019109.7
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr18_-_6490808 0.049 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr4_+_5724304 0.044 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr2_-_140671400 0.044 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr13_+_49582745 0.043 ENSMUST00000065494.7
Omd
osteomodulin
chr18_+_37655891 0.038 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr3_-_89960562 0.038 ENSMUST00000069805.7
Atp8b2
ATPase, class I, type 8B, member 2
chr7_-_45459839 0.037 ENSMUST00000094434.4
Ftl1
ferritin light chain 1
chr2_-_180824596 0.037 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr14_+_8098196 0.032 ENSMUST00000112689.2
ENSMUST00000036682.7
Pxk

PX domain containing serine/threonine kinase

chrX_+_13632769 0.031 ENSMUST00000096492.3
Gpr34
G protein-coupled receptor 34
chr3_+_66219909 0.030 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr1_-_105659008 0.029 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr14_+_47663756 0.028 ENSMUST00000022391.7
Ktn1
kinectin 1
chr15_-_79062866 0.028 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr15_-_98934522 0.027 ENSMUST00000077577.7
Tuba1b
tubulin, alpha 1B
chr11_-_110251736 0.025 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr12_+_33147754 0.022 ENSMUST00000146040.1
ENSMUST00000125192.1
Atxn7l1

ataxin 7-like 1

chr3_-_144760841 0.020 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.6 2.3 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.5 5.1 GO:0042572 retinol metabolic process(GO:0042572)
0.3 0.8 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 0.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 0.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 1.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.8 GO:0019236 response to pheromone(GO:0019236)
0.1 0.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 1.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.5 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 1.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.4 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.4 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.9 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.9 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.8 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.0 0.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.0 3.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.0 GO:0051238 sequestering of metal ion(GO:0051238)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.0 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.0 0.1 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0072534 perineuronal net(GO:0072534)
0.3 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 1.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 2.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 3.2 GO:0046625 sphingolipid binding(GO:0046625)
0.2 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.0 GO:0016208 AMP binding(GO:0016208)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.8 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.3 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 1.0 PID_ARF6_PATHWAY Arf6 signaling events
0.0 3.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.1 1.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases