Motif ID: Gfi1_Gfi1b
Z-value: 1.439


Transcription factors associated with Gfi1_Gfi1b:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gfi1 | ENSMUSG00000029275.11 | Gfi1 |
Gfi1b | ENSMUSG00000026815.8 | Gfi1b |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 10.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.6 | 6.2 | GO:2000768 | positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
1.0 | 3.0 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.8 | 2.5 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.5 | 1.5 | GO:0035622 | intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034) |
0.5 | 1.0 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
0.5 | 1.4 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
0.4 | 0.9 | GO:1990705 | cholangiocyte proliferation(GO:1990705) |
0.4 | 2.7 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
0.4 | 1.3 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.4 | 2.9 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
0.4 | 1.2 | GO:1904207 | chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
0.4 | 1.2 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
0.4 | 1.6 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
0.4 | 5.1 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
0.4 | 1.1 | GO:1990046 | positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046) |
0.3 | 1.3 | GO:0030043 | actin filament fragmentation(GO:0030043) |
0.3 | 0.9 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.3 | 10.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.3 | 1.0 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
0.2 | 1.0 | GO:0060578 | extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
0.2 | 0.7 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
0.2 | 0.9 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.2 | 1.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.2 | 0.8 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.2 | 0.6 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.2 | 0.6 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407) |
0.2 | 1.9 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.2 | 2.8 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.2 | 1.5 | GO:0072615 | interleukin-17 secretion(GO:0072615) |
0.2 | 0.2 | GO:1901630 | negative regulation of presynaptic membrane organization(GO:1901630) |
0.2 | 0.4 | GO:0032847 | regulation of cellular pH reduction(GO:0032847) |
0.2 | 0.6 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
0.2 | 0.7 | GO:1900150 | neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) regulation of defense response to fungus(GO:1900150) |
0.2 | 0.7 | GO:0097168 | condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168) |
0.2 | 1.3 | GO:0055064 | carbon dioxide transport(GO:0015670) chloride ion homeostasis(GO:0055064) |
0.2 | 1.3 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.2 | 0.6 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.2 | 0.8 | GO:0060849 | regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.2 | 0.5 | GO:0097274 | urea homeostasis(GO:0097274) |
0.2 | 0.5 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.1 | 0.6 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.1 | 1.3 | GO:0070141 | response to UV-A(GO:0070141) |
0.1 | 0.4 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.1 | 0.8 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.1 | 0.3 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
0.1 | 2.3 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.1 | 0.2 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
0.1 | 0.4 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.1 | 0.5 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.1 | 0.1 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
0.1 | 0.4 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.1 | 4.6 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.1 | 0.3 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313) |
0.1 | 0.5 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 0.3 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.1 | 0.6 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
0.1 | 1.0 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.1 | 0.5 | GO:0061085 | regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087) |
0.1 | 1.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 0.5 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
0.1 | 1.1 | GO:0061436 | establishment of skin barrier(GO:0061436) |
0.1 | 1.5 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.1 | 2.9 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 0.6 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.1 | 0.5 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.1 | 0.5 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 0.3 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.1 | 0.2 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
0.1 | 0.4 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.1 | 0.3 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.1 | 0.6 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.1 | 0.4 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
0.1 | 0.5 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.1 | 0.2 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.1 | 0.4 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
0.1 | 0.2 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.2 | GO:0071335 | hair follicle cell proliferation(GO:0071335) |
0.1 | 0.2 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
0.1 | 0.2 | GO:0032632 | interleukin-3 production(GO:0032632) |
0.1 | 0.5 | GO:0031424 | keratinization(GO:0031424) |
0.1 | 0.2 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.1 | 0.2 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.1 | 2.9 | GO:0000578 | embryonic axis specification(GO:0000578) |
0.1 | 2.0 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.1 | 0.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 0.6 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.1 | 0.2 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
0.1 | 0.2 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.1 | 0.3 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
0.1 | 0.6 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
0.1 | 0.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 0.8 | GO:0051601 | exocyst localization(GO:0051601) |
0.1 | 1.1 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
0.1 | 0.6 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.1 | 0.2 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.1 | 0.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.1 | 0.2 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
0.1 | 0.2 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.1 | 0.1 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
0.1 | 0.4 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.1 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 0.6 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.1 | 0.2 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.1 | 0.5 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.1 | 0.3 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
0.1 | 0.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.1 | 0.2 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
0.1 | 2.0 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.1 | 0.1 | GO:0045414 | regulation of interleukin-8 biosynthetic process(GO:0045414) |
0.1 | 0.9 | GO:0048368 | lateral mesoderm development(GO:0048368) |
0.1 | 0.6 | GO:0060013 | righting reflex(GO:0060013) |
0.1 | 0.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.5 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.0 | 0.1 | GO:0036363 | transforming growth factor beta activation(GO:0036363) |
0.0 | 0.3 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.0 | 0.2 | GO:0030576 | Cajal body organization(GO:0030576) |
0.0 | 0.3 | GO:0019731 | antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731) |
0.0 | 0.1 | GO:0030070 | insulin processing(GO:0030070) |
0.0 | 0.1 | GO:0015793 | glycerol transport(GO:0015793) renal water absorption(GO:0070295) |
0.0 | 0.6 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
0.0 | 1.1 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.2 | GO:0046210 | nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346) |
0.0 | 0.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.0 | 0.2 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
0.0 | 0.1 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
0.0 | 0.2 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177) |
0.0 | 0.2 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.6 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.0 | 1.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.6 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.1 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
0.0 | 0.8 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.0 | 0.4 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
0.0 | 0.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.0 | 0.2 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.0 | 2.0 | GO:0021884 | forebrain neuron development(GO:0021884) |
0.0 | 0.1 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 1.8 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
0.0 | 0.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.4 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
0.0 | 0.2 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.0 | 0.1 | GO:0090135 | B cell proliferation involved in immune response(GO:0002322) actin filament branching(GO:0090135) negative regulation of phospholipase C activity(GO:1900275) |
0.0 | 0.2 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
0.0 | 0.6 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.4 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
0.0 | 0.9 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 2.2 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.2 | GO:0016114 | terpenoid biosynthetic process(GO:0016114) |
0.0 | 0.1 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.0 | 0.4 | GO:0007413 | axonal fasciculation(GO:0007413) |
0.0 | 1.2 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.4 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.1 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
0.0 | 0.2 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.0 | 0.3 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.2 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.8 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
0.0 | 0.1 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.0 | 0.9 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
0.0 | 1.1 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
0.0 | 1.0 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.0 | 0.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.1 | GO:0051461 | corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.0 | 0.2 | GO:0050832 | defense response to fungus(GO:0050832) |
0.0 | 1.4 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 1.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
0.0 | 0.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.3 | GO:0030220 | platelet formation(GO:0030220) |
0.0 | 0.5 | GO:0006760 | folic acid-containing compound metabolic process(GO:0006760) |
0.0 | 1.0 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
0.0 | 0.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
0.0 | 0.0 | GO:0046881 | sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
0.0 | 0.3 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 1.7 | GO:0007286 | spermatid development(GO:0007286) |
0.0 | 0.8 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.0 | 0.2 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.0 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.0 | 0.4 | GO:0060479 | lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487) |
0.0 | 0.0 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.0 | 0.6 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
0.0 | 1.7 | GO:0008033 | tRNA processing(GO:0008033) |
0.0 | 0.0 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
0.0 | 0.1 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
0.0 | 0.8 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.0 | 0.2 | GO:0009062 | fatty acid catabolic process(GO:0009062) |
0.0 | 0.1 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
0.0 | 0.0 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.0 | 0.4 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.0 | 0.2 | GO:0035455 | response to interferon-alpha(GO:0035455) |
0.0 | 0.1 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.1 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.0 | 1.8 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 0.2 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.3 | GO:0034644 | cellular response to UV(GO:0034644) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.8 | 2.3 | GO:0071914 | prominosome(GO:0071914) |
0.3 | 0.9 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.3 | 1.7 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.3 | 0.6 | GO:0000799 | nuclear condensin complex(GO:0000799) |
0.2 | 1.7 | GO:0001520 | outer dense fiber(GO:0001520) meiotic spindle(GO:0072687) |
0.2 | 0.6 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.1 | 5.0 | GO:0030904 | retromer complex(GO:0030904) |
0.1 | 1.3 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 0.1 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
0.1 | 0.9 | GO:0008278 | cohesin complex(GO:0008278) |
0.1 | 1.0 | GO:0033269 | internode region of axon(GO:0033269) |
0.1 | 0.6 | GO:0001652 | granular component(GO:0001652) |
0.1 | 0.8 | GO:0042627 | chylomicron(GO:0042627) |
0.1 | 0.4 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.1 | 0.5 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 0.3 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.1 | 0.5 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.1 | 0.6 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 1.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 3.6 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 2.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 0.8 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.4 | GO:1990246 | uniplex complex(GO:1990246) |
0.1 | 0.6 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.1 | 1.1 | GO:0031105 | septin complex(GO:0031105) |
0.1 | 0.4 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 0.4 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.1 | 1.4 | GO:0045120 | pronucleus(GO:0045120) |
0.1 | 0.7 | GO:0005688 | U6 snRNP(GO:0005688) |
0.1 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.1 | 0.4 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
0.1 | 0.9 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.1 | 0.2 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 0.2 | GO:0070820 | tertiary granule(GO:0070820) |
0.1 | 0.4 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.1 | 0.2 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.1 | 0.2 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.1 | 0.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.6 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 2.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.1 | 2.3 | GO:0002102 | podosome(GO:0002102) |
0.1 | 0.3 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.1 | 3.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.5 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 2.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.2 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.0 | 0.1 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.0 | 0.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.3 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) |
0.0 | 0.4 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.9 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 1.4 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 0.7 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.9 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.2 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.0 | 0.3 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
0.0 | 4.4 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 0.3 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.3 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 0.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 9.2 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 0.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.0 | 0.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.0 | 0.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.4 | GO:0005838 | proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624) |
0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.2 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.0 | 1.5 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 1.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 1.3 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.0 | 1.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.0 | 0.1 | GO:0051286 | cell tip(GO:0051286) |
0.0 | 0.7 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.0 | 0.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.0 | GO:0005687 | U4 snRNP(GO:0005687) |
0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 0.2 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 0.0 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.0 | 0.8 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.1 | GO:0031201 | SNARE complex(GO:0031201) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
0.8 | 2.5 | GO:0016015 | morphogen activity(GO:0016015) |
0.5 | 2.7 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.4 | 1.3 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.4 | 1.5 | GO:0008142 | oxysterol binding(GO:0008142) |
0.3 | 1.0 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.3 | 1.0 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
0.3 | 1.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.3 | 0.8 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.2 | 0.7 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.2 | 2.2 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.2 | 0.8 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.2 | 0.5 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.2 | 1.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.2 | 1.1 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
0.1 | 1.0 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.7 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.1 | 2.8 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.1 | 0.4 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
0.1 | 0.5 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.1 | 0.4 | GO:1990254 | keratin filament binding(GO:1990254) |
0.1 | 1.5 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.1 | 1.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 1.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 0.3 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.1 | 0.6 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.1 | 0.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.1 | 3.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 1.1 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 0.5 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.3 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.1 | 0.4 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
0.1 | 1.1 | GO:0031996 | thioesterase binding(GO:0031996) |
0.1 | 0.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.7 | GO:0032564 | dATP binding(GO:0032564) |
0.1 | 2.8 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 1.7 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.1 | 2.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.1 | 0.5 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.1 | 0.2 | GO:0003796 | lysozyme activity(GO:0003796) |
0.1 | 0.8 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.1 | 0.2 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
0.1 | 0.4 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.1 | 1.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 0.7 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.1 | 0.6 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.1 | 0.3 | GO:0070051 | fibrinogen binding(GO:0070051) |
0.1 | 11.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.2 | GO:0070140 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
0.1 | 0.2 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
0.1 | 0.3 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 0.8 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 0.2 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.1 | 0.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 0.4 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 2.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 5.3 | GO:0035326 | enhancer binding(GO:0035326) |
0.1 | 0.7 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 2.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.1 | 0.7 | GO:0035198 | miRNA binding(GO:0035198) |
0.1 | 0.2 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 0.9 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.1 | 0.9 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 1.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 3.6 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.2 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.0 | 2.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.5 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
0.0 | 0.2 | GO:0016708 | nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726) |
0.0 | 0.2 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.0 | 0.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 1.0 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.0 | 0.4 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.3 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.5 | GO:0001618 | virus receptor activity(GO:0001618) |
0.0 | 0.1 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.0 | 0.2 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.0 | 0.4 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.6 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.1 | GO:0030911 | TPR domain binding(GO:0030911) |
0.0 | 0.8 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 1.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.2 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.0 | 0.1 | GO:0015254 | glycerol channel activity(GO:0015254) |
0.0 | 0.5 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 1.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.2 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 0.1 | GO:2001069 | glycogen binding(GO:2001069) |
0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 0.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.0 | 0.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.2 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
0.0 | 0.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.5 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 0.5 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.0 | 0.1 | GO:0070728 | leucine binding(GO:0070728) |
0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.4 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.4 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.0 | 0.5 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 1.4 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.2 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
0.0 | 0.2 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.0 | 0.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.0 | 0.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.4 | GO:0043566 | structure-specific DNA binding(GO:0043566) |
0.0 | 0.6 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 2.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.0 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.2 | GO:0030371 | translation repressor activity(GO:0030371) |
0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 1.0 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 2.4 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.0 | 0.1 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.0 | 0.1 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
0.0 | 2.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 1.2 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.4 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.2 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.0 | 0.1 | GO:0043028 | cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
0.0 | 4.6 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 4.1 | GO:0003682 | chromatin binding(GO:0003682) |
0.0 | 0.2 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 1.0 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
0.0 | 0.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.7 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 3.0 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.1 | 3.0 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 0.3 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 2.0 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 2.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 0.8 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 4.0 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 0.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 2.2 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.0 | 1.0 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 3.1 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.8 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.5 | PID_IL23_PATHWAY | IL23-mediated signaling events |
0.0 | 0.4 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.0 | 0.6 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.0 | 1.2 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.9 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
0.0 | 1.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.2 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.9 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.2 | 3.3 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 2.2 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 2.2 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.1 | 2.2 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.1 | 1.4 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.1 | 5.9 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.1 | 2.8 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.1 | 4.9 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.1 | 1.3 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.1 | 1.7 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.1 | 0.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 0.8 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.1 | 0.9 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.1 | 1.0 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 0.6 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.1 | 2.9 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.1 | 0.6 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.1 | 1.4 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.0 | 0.4 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.0 | 0.6 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 1.0 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 3.1 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.7 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 1.3 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.5 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
0.0 | 0.3 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 0.5 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.4 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 1.8 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.2 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.0 | 0.5 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 2.3 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.0 | 1.3 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 0.1 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 0.8 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.4 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.5 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.8 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.3 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.6 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 0.2 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.1 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 0.2 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.2 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.2 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.0 | 0.1 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.0 | 0.5 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 0.3 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.0 | 0.3 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |