Motif ID: Nr2c1

Z-value: 0.694


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_941480230.107.0e-01Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_46991842 2.127 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr9_-_29411736 2.091 ENSMUST00000115236.1
Ntm
neurotrimin
chr15_+_80091320 2.064 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr9_-_29412204 1.961 ENSMUST00000115237.1
Ntm
neurotrimin
chr10_-_86498836 1.785 ENSMUST00000120638.1
Syn3
synapsin III
chr10_+_58813359 1.756 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr1_-_155417283 1.723 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr12_-_83487708 1.421 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr7_+_110768169 1.360 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr6_-_142964404 1.274 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr6_+_22875496 1.267 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr9_-_21037775 1.234 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr5_+_117120120 1.211 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr1_-_58586191 1.186 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr11_+_75193783 1.160 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr2_-_29253001 1.108 ENSMUST00000071201.4
Ntng2
netrin G2
chr16_-_44139630 1.078 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr11_-_26210553 1.038 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr11_-_76577701 1.004 ENSMUST00000176179.1
Abr
active BCR-related gene
chr7_+_46397648 0.965 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr4_+_133039482 0.938 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr17_-_35909626 0.937 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr15_+_81811414 0.849 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr17_-_35910032 0.829 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr7_+_45896941 0.819 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr10_-_86498872 0.757 ENSMUST00000121789.1
Syn3
synapsin III
chr12_+_61523889 0.748 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr15_-_98093245 0.695 ENSMUST00000180657.1
Senp1
SUMO1/sentrin specific peptidase 1
chr4_-_129440800 0.693 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr3_+_68572245 0.661 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr19_+_46152505 0.645 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr5_-_137741601 0.609 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr15_-_79141197 0.606 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr1_+_58973521 0.603 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta

chr16_-_4523056 0.597 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr15_+_89429560 0.571 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr7_+_45897429 0.560 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr6_+_125145235 0.558 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr19_-_45998479 0.520 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr5_+_105519388 0.517 ENSMUST00000067924.6
ENSMUST00000150981.1
Lrrc8c

leucine rich repeat containing 8 family, member C

chr2_+_130406478 0.513 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr15_-_89429093 0.503 ENSMUST00000170460.1
Chkb
choline kinase beta
chr12_+_83987854 0.489 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr11_-_3504766 0.474 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr13_-_9878998 0.473 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr10_+_127705170 0.460 ENSMUST00000079590.5
Myo1a
myosin IA
chr1_+_180726019 0.452 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chrX_+_10485121 0.441 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr1_-_58973421 0.434 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr4_+_127172866 0.432 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr15_+_3270767 0.421 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr2_+_164805082 0.384 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr16_-_44139196 0.373 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr4_+_129461581 0.372 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1

BSD domain containing 1

chr9_+_118506226 0.369 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr11_+_62281457 0.342 ENSMUST00000101075.4
ENSMUST00000050646.6
Ttc19

tetratricopeptide repeat domain 19

chrX_-_59567348 0.342 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr11_-_107337556 0.335 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr15_+_86214431 0.335 ENSMUST00000063414.8
Tbc1d22a
TBC1 domain family, member 22a
chr2_+_153345809 0.333 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr17_-_46032366 0.325 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr4_+_156215920 0.324 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr14_+_20674311 0.296 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr15_-_89425795 0.285 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr13_-_93192270 0.261 ENSMUST00000048702.5
Papd4
PAP associated domain containing 4
chr11_-_97766508 0.261 ENSMUST00000107579.1
ENSMUST00000018685.2
Cwc25

CWC25 spliceosome-associated protein homolog (S. cerevisiae)

chr13_+_84222286 0.258 ENSMUST00000057495.8
Tmem161b
transmembrane protein 161B
chr13_+_31558157 0.227 ENSMUST00000042118.8
Foxq1
forkhead box Q1
chr1_+_195017399 0.221 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr1_+_59256906 0.212 ENSMUST00000160662.1
ENSMUST00000114248.2
Cdk15

cyclin-dependent kinase 15

chr1_-_172632931 0.208 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr5_-_5265224 0.200 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr7_-_28598140 0.200 ENSMUST00000108283.1
ENSMUST00000040531.8
Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr2_+_22895583 0.198 ENSMUST00000152170.1
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr11_-_62281342 0.190 ENSMUST00000072916.4
Zswim7
zinc finger SWIM-type containing 7
chr4_+_137993016 0.187 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr10_-_67548944 0.181 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr14_+_54360826 0.164 ENSMUST00000000985.5
Oxa1l
oxidase assembly 1-like
chr19_-_6921753 0.153 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chr19_-_5688149 0.151 ENSMUST00000068169.5
Pcnxl3
pecanex-like 3 (Drosophila)
chr17_-_12992188 0.146 ENSMUST00000159986.1
Wtap
Wilms' tumour 1-associating protein
chr10_-_4432312 0.144 ENSMUST00000126102.1
ENSMUST00000131853.1
ENSMUST00000042251.4
Rmnd1


required for meiotic nuclear division 1 homolog (S. cerevisiae)


chr19_-_6921804 0.143 ENSMUST00000025906.4
Esrra
estrogen related receptor, alpha
chr6_-_83054415 0.139 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr10_-_119240006 0.139 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr4_+_150853919 0.130 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr13_+_44729794 0.123 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr16_+_44139821 0.091 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr9_+_107340593 0.085 ENSMUST00000042581.2
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr3_+_58526303 0.075 ENSMUST00000138848.1
Eif2a
eukaryotic translation initiation factor 2A
chr12_+_4082574 0.070 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_+_30712209 0.053 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr1_-_156939387 0.047 ENSMUST00000171292.1
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr11_+_116853752 0.045 ENSMUST00000021173.7
Mfsd11
major facilitator superfamily domain containing 11
chr3_+_32529532 0.041 ENSMUST00000147350.1
Mfn1
mitofusin 1
chr5_+_135187251 0.040 ENSMUST00000002825.5
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr1_-_156718894 0.039 ENSMUST00000086153.6
Fam20b
family with sequence similarity 20, member B
chr17_-_12992227 0.035 ENSMUST00000007007.7
Wtap
Wilms' tumour 1-associating protein
chr4_-_41048124 0.017 ENSMUST00000030136.6
Aqp7
aquaporin 7
chr9_+_65101453 0.015 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
Igdcc4


immunoglobulin superfamily, DCC subclass, member 4


chr1_+_133309778 0.013 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr7_+_82648595 0.011 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
Eftud1


elongation factor Tu GTP binding domain containing 1


chr17_-_51810866 0.001 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.3 1.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.6 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 1.4 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 2.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.6 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 2.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.3 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.7 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 4.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.5 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 2.2 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 1.3 GO:0072534 perineuronal net(GO:0072534)
0.2 1.8 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 4.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.4 GO:0071565 nBAF complex(GO:0071565)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 2.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 1.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.7 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 2.1 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac