Motif ID: Mef2d_Mef2a

Z-value: 1.206

Transcription factors associated with Mef2d_Mef2a:

Gene SymbolEntrez IDGene Name
Mef2a ENSMUSG00000030557.10 Mef2a
Mef2d ENSMUSG00000001419.11 Mef2d

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2amm10_v2_chr7_-_67372846_673728580.881.5e-06Click!
Mef2dmm10_v2_chr3_+_88142328_881424830.551.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2d_Mef2a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_83573577 7.755 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr13_+_23934434 5.065 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr19_+_38264761 4.830 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr4_+_144892813 4.700 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr1_-_134234492 4.528 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr6_+_58831748 4.505 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr3_-_56183678 4.215 ENSMUST00000029374.6
Nbea
neurobeachin
chr1_-_64122256 4.190 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr6_-_136171722 4.134 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_+_75152274 3.948 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr7_+_91090697 3.931 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr9_-_112232449 3.900 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr11_+_31872100 3.848 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr7_+_91090728 3.828 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr4_+_144893077 3.605 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr13_-_113663670 3.522 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr16_+_45093611 3.463 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr16_+_7069825 3.432 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr15_+_101266839 3.333 ENSMUST00000023779.6
Nr4a1
nuclear receptor subfamily 4, group A, member 1
chr18_-_31949571 3.321 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr1_+_75375271 3.288 ENSMUST00000087122.5
Speg
SPEG complex locus
chr14_-_36919314 3.232 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chrX_-_51681703 3.231 ENSMUST00000088172.5
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr14_-_36919513 3.201 ENSMUST00000182042.1
Ccser2
coiled-coil serine rich 2
chr14_+_101729907 3.168 ENSMUST00000100337.3
Lmo7
LIM domain only 7
chr13_+_5861489 3.063 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chrX_-_51681856 3.027 ENSMUST00000114871.1
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr10_+_69785507 2.990 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chr4_+_144893127 2.974 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_-_33371400 2.889 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr14_+_101840602 2.821 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr13_+_42680565 2.696 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr7_-_67372846 2.637 ENSMUST00000156690.1
ENSMUST00000107476.1
ENSMUST00000076325.5
ENSMUST00000032776.8
ENSMUST00000133074.1
Mef2a




myocyte enhancer factor 2A




chr19_-_5802640 2.614 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
Malat1


metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)


chr2_-_33371486 2.547 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr5_+_66745835 2.494 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr9_-_49798905 2.482 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr2_+_118663235 2.467 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_+_71048338 2.418 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr5_+_19907774 2.366 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_16011851 2.279 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr9_+_34904913 2.227 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr14_+_101840501 2.225 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr2_-_168712853 2.186 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr3_-_85722474 2.162 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr10_+_90576872 2.157 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr9_-_101198999 2.133 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr9_-_49798729 2.122 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr19_-_46327121 2.107 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr11_+_111066154 2.098 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_-_34528844 2.046 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr12_+_69241832 1.912 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr10_-_25200110 1.890 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr17_+_70522083 1.888 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr19_-_37176055 1.887 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr13_+_16014457 1.817 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr14_-_64455903 1.779 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr19_-_5924797 1.772 ENSMUST00000055458.4
Cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr1_-_64121389 1.759 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr8_+_76902277 1.744 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr7_-_127824469 1.710 ENSMUST00000106267.3
Stx1b
syntaxin 1B
chr5_+_105519388 1.704 ENSMUST00000067924.6
ENSMUST00000150981.1
Lrrc8c

leucine rich repeat containing 8 family, member C

chr17_-_67950908 1.700 ENSMUST00000164647.1
Arhgap28
Rho GTPase activating protein 28
chr11_+_3330401 1.698 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr18_-_38601268 1.692 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr5_+_107497762 1.623 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr12_+_52699297 1.617 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr1_+_177445660 1.581 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr8_-_71671723 1.557 ENSMUST00000177517.1
ENSMUST00000030170.8
Unc13a

unc-13 homolog A (C. elegans)

chr16_+_43235856 1.527 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr15_-_89425795 1.438 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr1_+_63445842 1.429 ENSMUST00000087374.3
ENSMUST00000114107.1
ENSMUST00000182642.1
Adam23


a disintegrin and metallopeptidase domain 23


chr5_+_138280538 1.415 ENSMUST00000162245.1
ENSMUST00000161691.1
Stag3

stromal antigen 3

chr2_-_77703252 1.373 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr5_+_107497718 1.369 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr18_-_25753852 1.349 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr18_-_37969742 1.343 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr15_+_9140527 1.330 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr5_+_138280516 1.312 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr6_+_42286709 1.298 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr2_-_65022740 1.268 ENSMUST00000028252.7
Grb14
growth factor receptor bound protein 14
chr1_-_64121456 1.245 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr2_+_32628390 1.232 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr2_+_19658055 1.218 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr7_-_97417730 1.214 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr1_-_172297989 1.210 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr2_-_65567465 1.202 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr9_-_112187898 1.185 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr18_+_67464849 1.183 ENSMUST00000025411.7
Slmo1
slowmo homolog 1 (Drosophila)
chr9_-_75599124 1.180 ENSMUST00000098552.2
Tmod2
tropomodulin 2
chr2_-_65567505 1.176 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_+_137410721 1.171 ENSMUST00000167002.1
Ptpro
protein tyrosine phosphatase, receptor type, O
chr4_+_156215920 1.166 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr9_-_112187766 1.163 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_-_152766281 1.131 ENSMUST00000111859.1
ENSMUST00000148865.1
Rgl1

ral guanine nucleotide dissociation stimulator,-like 1

chrX_-_47892502 1.109 ENSMUST00000077569.4
ENSMUST00000101616.2
ENSMUST00000088973.4
Smarca1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr16_+_43363855 1.107 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr12_-_112929415 1.079 ENSMUST00000075827.3
Jag2
jagged 2
chr3_+_68584154 1.076 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chrX_-_47892396 1.076 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr11_-_69369377 1.072 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr2_+_32625431 1.056 ENSMUST00000113277.1
Ak1
adenylate kinase 1
chr2_-_77170592 1.053 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr7_+_30121915 1.041 ENSMUST00000098596.3
ENSMUST00000153792.1
Zfp382

zinc finger protein 382

chr6_+_42286676 1.018 ENSMUST00000031894.6
Clcn1
chloride channel 1
chrX_-_47892432 0.998 ENSMUST00000141084.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr6_-_142702259 0.994 ENSMUST00000073173.5
ENSMUST00000111771.1
ENSMUST00000087527.4
ENSMUST00000100827.2
Abcc9



ATP-binding cassette, sub-family C (CFTR/MRP), member 9



chr14_-_93888732 0.980 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr3_+_103279293 0.976 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr11_-_69801716 0.968 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr6_+_116650674 0.964 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr2_-_25469742 0.941 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chrX_-_165004829 0.939 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr9_-_77347816 0.931 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr1_+_180851131 0.911 ENSMUST00000038091.6
Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr3_+_96596628 0.910 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr1_-_30863256 0.904 ENSMUST00000088310.3
Phf3
PHD finger protein 3
chr16_+_43364145 0.900 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr14_+_65968483 0.893 ENSMUST00000022616.6
Clu
clusterin
chr11_-_102218923 0.887 ENSMUST00000131254.1
Hdac5
histone deacetylase 5
chr2_+_3513035 0.838 ENSMUST00000036350.2
Cdnf
cerebral dopamine neurotrophic factor
chr5_-_62765618 0.829 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_111761697 0.822 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr3_+_138065052 0.815 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr18_+_37473538 0.813 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr2_-_164833438 0.802 ENSMUST00000042775.4
Neurl2
neuralized-like 2 (Drosophila)
chr8_-_41016749 0.800 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr2_+_107290590 0.781 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr7_-_45366714 0.780 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr7_-_80371197 0.777 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chr5_-_123140135 0.774 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr1_+_34121250 0.723 ENSMUST00000183006.1
Dst
dystonin
chr11_-_120630516 0.711 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr2_-_25470031 0.702 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr4_+_62663620 0.680 ENSMUST00000126338.1
Rgs3
regulator of G-protein signaling 3
chr2_+_48949495 0.670 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr6_-_128124312 0.663 ENSMUST00000127105.1
Tspan9
tetraspanin 9
chr18_+_76059458 0.663 ENSMUST00000167921.1
Zbtb7c
zinc finger and BTB domain containing 7C
chr17_+_85028347 0.663 ENSMUST00000024944.7
Slc3a1
solute carrier family 3, member 1
chr9_+_75071579 0.643 ENSMUST00000136731.1
Myo5a
myosin VA
chr2_-_27027909 0.610 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chr13_+_20090538 0.604 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr5_-_128953303 0.604 ENSMUST00000111346.1
Rimbp2
RIMS binding protein 2
chr13_+_20090500 0.600 ENSMUST00000165249.2
Elmo1
engulfment and cell motility 1
chr9_-_77347787 0.593 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr18_-_79109391 0.589 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chrX_-_59567348 0.586 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr15_-_95528228 0.577 ENSMUST00000075275.2
Nell2
NEL-like 2
chr2_-_119541513 0.576 ENSMUST00000171024.1
Exd1
exonuclease 3'-5' domain containing 1
chr1_-_16520020 0.559 ENSMUST00000144138.2
ENSMUST00000145092.1
Stau2

staufen (RNA binding protein) homolog 2 (Drosophila)

chrX_-_59568068 0.550 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr16_-_35769356 0.535 ENSMUST00000023554.8
Dirc2
disrupted in renal carcinoma 2 (human)
chr16_-_14159232 0.530 ENSMUST00000090300.4
Marf1
meiosis arrest female 1
chr13_-_107890059 0.527 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr3_-_95882232 0.523 ENSMUST00000161866.1
Gm129
predicted gene 129
chr11_-_107716517 0.505 ENSMUST00000021065.5
Cacng1
calcium channel, voltage-dependent, gamma subunit 1
chr7_+_112742025 0.505 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr16_+_14705832 0.494 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr5_+_24985840 0.493 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr13_-_74363993 0.482 ENSMUST00000022064.4
Lrrc14b
leucine rich repeat containing 14B
chr16_-_4523056 0.472 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr11_+_54304005 0.464 ENSMUST00000000145.5
ENSMUST00000138515.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr4_-_44066960 0.462 ENSMUST00000173234.1
ENSMUST00000173274.1
Gne

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr1_-_16520106 0.459 ENSMUST00000162435.1
Stau2
staufen (RNA binding protein) homolog 2 (Drosophila)
chr10_-_69212996 0.451 ENSMUST00000170048.1
A930033H14Rik
RIKEN cDNA A930033H14 gene
chr2_+_72054598 0.431 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr1_-_16520067 0.422 ENSMUST00000131257.2
ENSMUST00000153966.2
Stau2

staufen (RNA binding protein) homolog 2 (Drosophila)

chr11_+_54304180 0.401 ENSMUST00000108904.3
ENSMUST00000108905.3
Acsl6

acyl-CoA synthetase long-chain family member 6

chr19_+_41582370 0.391 ENSMUST00000172371.1
Gm340
predicted gene 340
chr5_+_25759987 0.389 ENSMUST00000128727.1
ENSMUST00000088244.4
Actr3b

ARP3 actin-related protein 3B

chr1_+_134193432 0.385 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr11_-_120630126 0.380 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr9_+_75071386 0.370 ENSMUST00000155282.2
Myo5a
myosin VA
chr2_+_79635416 0.364 ENSMUST00000111788.1
Ssfa2
sperm specific antigen 2
chr17_+_44188564 0.362 ENSMUST00000024755.5
Clic5
chloride intracellular channel 5
chr13_-_83729544 0.358 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr7_-_31055594 0.356 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr2_+_69670100 0.356 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr14_-_60197173 0.353 ENSMUST00000131670.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chrX_+_101449078 0.345 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr1_+_16688405 0.344 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr16_+_8513429 0.321 ENSMUST00000065987.7
ENSMUST00000115838.1
ENSMUST00000115839.2
Abat


4-aminobutyrate aminotransferase


chr9_+_104566677 0.320 ENSMUST00000157006.1
Cpne4
copine IV
chr2_-_104028287 0.315 ENSMUST00000056170.3
4931422A03Rik
RIKEN cDNA 4931422A03 gene
chr11_+_54303798 0.305 ENSMUST00000093106.5
Acsl6
acyl-CoA synthetase long-chain family member 6
chr11_+_102284931 0.301 ENSMUST00000036376.6
ENSMUST00000100387.4
Tmub2

transmembrane and ubiquitin-like domain containing 2

chr2_+_79635352 0.300 ENSMUST00000111785.2
Ssfa2
sperm specific antigen 2
chr15_-_82912134 0.289 ENSMUST00000048966.5
ENSMUST00000109510.2
Tcf20

transcription factor 20

chrX_+_38189780 0.281 ENSMUST00000049740.2
ENSMUST00000115142.2
Zbtb33

zinc finger and BTB domain containing 33

chr11_+_102285161 0.275 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr2_+_129198757 0.269 ENSMUST00000028880.3
Slc20a1
solute carrier family 20, member 1
chr9_-_70141484 0.265 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr14_-_66280949 0.260 ENSMUST00000111121.1
ENSMUST00000022622.7
ENSMUST00000089250.2
Ptk2b


PTK2 protein tyrosine kinase 2 beta


chr4_-_127313980 0.255 ENSMUST00000053753.7
Gja4
gap junction protein, alpha 4
chr11_+_77462325 0.253 ENSMUST00000102493.1
Coro6
coronin 6
chr3_+_95164306 0.250 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr3_+_116562965 0.243 ENSMUST00000029573.5
Lrrc39
leucine rich repeat containing 39
chr3_+_68869563 0.240 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr1_-_186705980 0.240 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr15_+_25940846 0.230 ENSMUST00000110438.1
Fam134b
family with sequence similarity 134, member B

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
1.5 4.6 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.5 4.5 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.3 3.9 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
1.1 5.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
1.0 6.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.0 4.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.0 10.9 GO:0042572 retinol metabolic process(GO:0042572)
0.9 2.6 GO:0070375 ERK5 cascade(GO:0070375)
0.8 4.1 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.7 2.1 GO:0007525 somatic muscle development(GO:0007525)
0.7 2.7 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.6 1.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 3.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.6 7.8 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.5 2.6 GO:0035063 nuclear speck organization(GO:0035063)
0.5 3.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.5 2.4 GO:0046684 response to pyrethroid(GO:0046684)
0.4 2.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.4 1.7 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.4 1.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 1.3 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4 3.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.4 1.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.4 2.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.4 2.3 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.3 1.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 2.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 2.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 3.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.8 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.3 1.6 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.3 1.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 0.5 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 1.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 3.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.2 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.2 2.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 1.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 1.9 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 0.4 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.2 2.1 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.2 1.1 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.9 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 1.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 1.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 1.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.5 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 0.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 1.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.1 GO:0001553 luteinization(GO:0001553)
0.1 4.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.3 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.1 3.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.4 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 6.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.4 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.1 1.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 0.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 2.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 4.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 4.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 2.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 1.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 2.5 GO:0007613 memory(GO:0007613)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 1.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 5.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.1 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 1.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 4.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.6 GO:0021766 hippocampus development(GO:0021766)
0.0 4.0 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.5 GO:0007143 female meiotic division(GO:0007143)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.5 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 1.8 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 2.6 GO:0060541 respiratory system development(GO:0060541)
0.0 0.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 1.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.1 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0043512 inhibin A complex(GO:0043512)
0.9 2.7 GO:0000802 transverse filament(GO:0000802)
0.8 3.2 GO:0090537 CERF complex(GO:0090537)
0.4 7.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 7.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 1.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.3 5.3 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.6 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.3 2.3 GO:0001520 outer dense fiber(GO:0001520)
0.3 4.1 GO:0043083 synaptic cleft(GO:0043083)
0.3 0.8 GO:0005927 muscle tendon junction(GO:0005927)
0.3 2.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 3.5 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.2 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 3.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 4.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 5.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 7.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 5.2 GO:0001650 fibrillar center(GO:0001650)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 3.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 6.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 8.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 3.0 GO:0030054 cell junction(GO:0030054)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.6 6.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
1.1 6.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.1 6.5 GO:0070699 type II activin receptor binding(GO:0070699)
1.1 3.2 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.8 3.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.6 4.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.6 1.8 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.6 1.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 4.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.4 1.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.4 7.8 GO:0035198 miRNA binding(GO:0035198)
0.3 7.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 5.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 2.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 4.5 GO:0030275 LRR domain binding(GO:0030275)
0.2 2.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 5.7 GO:0042805 actinin binding(GO:0042805)
0.2 3.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 1.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 4.2 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.2 GO:1990239 steroid hormone binding(GO:1990239)
0.1 3.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.8 GO:0030955 potassium ion binding(GO:0030955)
0.1 3.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 4.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 7.2 GO:0008017 microtubule binding(GO:0008017)
0.0 1.4 GO:0019894 kinesin binding(GO:0019894)
0.0 1.4 GO:0042562 hormone binding(GO:0042562)
0.0 2.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 2.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.8 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID_FGF_PATHWAY FGF signaling pathway
0.2 10.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 7.0 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.1 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.1 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 2.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.7 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 4.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.1 PID_P73PATHWAY p73 transcription factor network
0.0 0.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
1.0 4.1 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.4 4.5 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 9.3 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 4.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.2 2.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 6.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.7 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.6 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.1 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 3.9 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.2 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation