Motif ID: Pbx2

Z-value: 0.777


Transcription factors associated with Pbx2:

Gene SymbolEntrez IDGene Name
Pbx2 ENSMUSG00000034673.8 Pbx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pbx2mm10_v2_chr17_+_34592248_34592329-0.791.1e-04Click!


Activity profile for motif Pbx2.

activity profile for motif Pbx2


Sorted Z-values histogram for motif Pbx2

Sorted Z-values for motif Pbx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pbx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66812593 3.659 ENSMUST00000100572.3
Sla
src-like adaptor
chr2_+_65620829 2.427 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr5_+_106609098 2.413 ENSMUST00000167618.1
Gm17304
predicted gene, 17304
chr15_+_21111452 2.176 ENSMUST00000075132.6
Cdh12
cadherin 12
chr6_+_8259288 2.027 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr2_-_104257400 1.845 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr3_+_121953213 1.702 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr1_-_56972437 1.607 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr6_+_8259327 1.606 ENSMUST00000159378.1
Gm16039
predicted gene 16039
chrX_+_140367494 1.487 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr3_-_152982240 1.449 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_+_3330401 1.331 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_+_3330781 1.315 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr6_+_8259379 1.310 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr15_+_92597104 1.227 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr9_+_112234257 0.985 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr8_+_72646679 0.981 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr2_+_128967383 0.973 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr8_+_72646728 0.870 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chrX_-_70365052 0.863 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr6_-_143947061 0.860 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr11_-_79504078 0.822 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr13_-_113663670 0.819 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr17_-_45686899 0.761 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chrX_+_134295225 0.732 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chr8_-_54724317 0.715 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr14_+_65969714 0.711 ENSMUST00000153460.1
Clu
clusterin
chr1_-_176807124 0.668 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chrX_+_73064787 0.649 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr8_-_54724474 0.631 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr16_-_91728701 0.623 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr17_+_8849974 0.606 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr6_-_143947092 0.606 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr19_-_32061438 0.605 ENSMUST00000096119.4
Asah2
N-acylsphingosine amidohydrolase 2
chrX_+_38600626 0.598 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr3_+_68572245 0.595 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chrX_-_8175890 0.545 ENSMUST00000143984.1
Tbc1d25
TBC1 domain family, member 25
chr8_+_90828820 0.524 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr18_+_77938452 0.519 ENSMUST00000044622.5
Epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr8_+_93810832 0.489 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr17_+_21690766 0.487 ENSMUST00000097384.1
Gm10509
predicted gene 10509
chr18_+_37725706 0.477 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr18_-_31820413 0.457 ENSMUST00000165131.2
Gm6665
predicted gene 6665
chr9_-_42399709 0.456 ENSMUST00000160940.1
Tecta
tectorin alpha
chr13_-_25270076 0.455 ENSMUST00000057866.6
Nrsn1
neurensin 1
chr11_-_120643643 0.440 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr9_-_54661870 0.409 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr2_-_132578244 0.399 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr3_-_107943705 0.387 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
Gstm6


glutathione S-transferase, mu 6


chr4_+_42949814 0.366 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr7_-_12818837 0.364 ENSMUST00000121215.1
ENSMUST00000108546.1
ENSMUST00000072222.7
Zfp329


zinc finger protein 329


chr8_-_41054771 0.363 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr1_-_23909687 0.358 ENSMUST00000129254.1
Smap1
small ArfGAP 1
chr16_-_37384915 0.345 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr9_-_54661666 0.332 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chrX_+_20364481 0.326 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr16_+_32332238 0.324 ENSMUST00000115151.3
Ubxn7
UBX domain protein 7
chr5_-_113280572 0.319 ENSMUST00000112324.1
ENSMUST00000057209.5
Sgsm1

small G protein signaling modulator 1

chr15_+_85510812 0.309 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr7_+_49974864 0.300 ENSMUST00000081872.5
ENSMUST00000151721.1
Nell1

NEL-like 1

chr5_-_114773372 0.294 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr13_+_60602182 0.290 ENSMUST00000044083.7
Dapk1
death associated protein kinase 1
chr3_-_107943362 0.288 ENSMUST00000106683.1
Gstm6
glutathione S-transferase, mu 6
chr3_+_79884496 0.284 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr5_-_114773488 0.282 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chr13_+_60601921 0.278 ENSMUST00000077453.5
Dapk1
death associated protein kinase 1
chr14_-_7483762 0.273 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr17_+_7170101 0.260 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr12_+_71015966 0.252 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr6_-_8259098 0.243 ENSMUST00000012627.4
Rpa3
replication protein A3
chrX_-_122397351 0.240 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr12_-_8499985 0.237 ENSMUST00000067384.4
Rhob
ras homolog gene family, member B
chr14_+_61599493 0.236 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr18_-_73754457 0.225 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr2_+_23068168 0.216 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chr3_+_152346465 0.216 ENSMUST00000026507.6
ENSMUST00000117492.2
Usp33

ubiquitin specific peptidase 33

chr11_-_98149551 0.203 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr1_+_171271627 0.201 ENSMUST00000141114.1
B4galt3
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
chr5_-_34288407 0.201 ENSMUST00000114368.1
ENSMUST00000114369.1
Zfyve28

zinc finger, FYVE domain containing 28

chr14_+_30825580 0.201 ENSMUST00000006701.5
Tmem110
transmembrane protein 110
chr2_+_119594288 0.198 ENSMUST00000147425.1
ENSMUST00000153581.1
1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr17_-_24527830 0.194 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr2_+_175275125 0.186 ENSMUST00000109051.1
Gm14440
predicted gene 14440
chr17_+_78508063 0.185 ENSMUST00000024880.9
Vit
vitrin
chr19_-_3575708 0.184 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr8_-_94696223 0.182 ENSMUST00000034227.4
Pllp
plasma membrane proteolipid
chr4_-_150003130 0.173 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr17_-_24527925 0.167 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr5_-_109691041 0.152 ENSMUST00000092720.3
5430403G16Rik
RIKEN cDNA 5430403G16 gene
chr9_+_44398176 0.149 ENSMUST00000165839.1
Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr17_+_21691860 0.148 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr11_-_115708538 0.147 ENSMUST00000106495.1
ENSMUST00000021090.7
Grb2

growth factor receptor bound protein 2

chr4_-_43046196 0.142 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr9_+_92309362 0.138 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr3_-_106790143 0.136 ENSMUST00000038845.8
Cd53
CD53 antigen
chr1_+_169928648 0.134 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr5_+_24394388 0.128 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr2_+_177897096 0.124 ENSMUST00000108935.1
Gm14327
predicted gene 14327
chr6_-_42693030 0.121 ENSMUST00000045140.4
Fam115a
family with sequence similarity 115, member A
chr1_+_134560190 0.119 ENSMUST00000112198.1
ENSMUST00000112197.1
Kdm5b

lysine (K)-specific demethylase 5B

chr7_-_104950441 0.117 ENSMUST00000179862.1
Gm5900
predicted pseudogene 5900
chrX_-_75578188 0.110 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr5_+_8660059 0.087 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr6_-_127109517 0.086 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr11_-_72215592 0.086 ENSMUST00000021157.8
Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr6_-_42693087 0.085 ENSMUST00000121083.1
Fam115a
family with sequence similarity 115, member A
chr17_+_37193889 0.085 ENSMUST00000038844.6
Ubd
ubiquitin D
chr2_+_55411790 0.081 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr9_+_119341294 0.073 ENSMUST00000039784.5
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
chr11_-_110251736 0.072 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr19_+_11912389 0.069 ENSMUST00000061618.7
Patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr17_+_24886643 0.057 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr10_-_119240006 0.056 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr2_-_86347764 0.053 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr11_+_5520652 0.043 ENSMUST00000063084.9
Xbp1
X-box binding protein 1
chr13_+_3538075 0.035 ENSMUST00000059515.6
Gdi2
guanosine diphosphate (GDP) dissociation inhibitor 2
chr15_+_74563738 0.028 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr12_-_103425780 0.027 ENSMUST00000110001.2
ENSMUST00000044923.7
Ddx24

DEAD (Asp-Glu-Ala-Asp) box polypeptide 24

chr11_-_79296906 0.025 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr9_-_113708209 0.023 ENSMUST00000111861.3
ENSMUST00000035086.6
Pdcd6ip

programmed cell death 6 interacting protein

chr11_-_110095937 0.022 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr7_-_27178835 0.021 ENSMUST00000093040.6
Rab4b
RAB4B, member RAS oncogene family
chr8_-_8639363 0.018 ENSMUST00000152698.1
Efnb2
ephrin B2
chr12_-_55302974 0.018 ENSMUST00000021410.8
Ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
chr9_-_108263706 0.018 ENSMUST00000171412.1
Dag1
dystroglycan 1
chr4_+_15881255 0.016 ENSMUST00000029876.1
Calb1
calbindin 1
chr16_-_93603803 0.012 ENSMUST00000023669.5
ENSMUST00000113951.2
Setd4

SET domain containing 4

chr15_+_16778101 0.007 ENSMUST00000026432.6
Cdh9
cadherin 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.7 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 1.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.3 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 3.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.8 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.0 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0051926 dopamine receptor signaling pathway(GO:0007212) negative regulation of calcium ion transport(GO:0051926)
0.0 0.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 1.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 4.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 3.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 3.5 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 3.1 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 2.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation