Motif ID: Zfp652

Z-value: 0.894


Transcription factors associated with Zfp652:

Gene SymbolEntrez IDGene Name
Zfp652 ENSMUSG00000075595.3 Zfp652

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp652mm10_v2_chr11_+_95712673_95712673-0.243.5e-01Click!


Activity profile for motif Zfp652.

activity profile for motif Zfp652


Sorted Z-values histogram for motif Zfp652

Sorted Z-values for motif Zfp652



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp652

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_53707532 6.142 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr10_+_26229707 3.519 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr16_+_30065333 3.056 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr10_-_92165159 3.003 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_-_138847579 2.648 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr12_+_55598917 2.322 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr3_+_87971129 2.188 ENSMUST00000160694.1
Nes
nestin
chr3_+_87971071 2.180 ENSMUST00000090973.5
Nes
nestin
chr1_+_153665666 2.157 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr7_-_25788635 2.108 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chrX_-_48034842 2.098 ENSMUST00000039026.7
Apln
apelin
chr2_+_167777467 2.029 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr1_+_153665274 2.022 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr11_-_94242701 1.743 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_+_153665587 1.737 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 1.732 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr4_-_63403330 1.717 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr14_+_73237891 1.707 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr3_-_116129615 1.649 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr1_+_184034381 1.542 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr2_+_4882204 1.494 ENSMUST00000115019.1
Sephs1
selenophosphate synthetase 1
chr10_-_6980376 1.469 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr5_+_115908644 1.444 ENSMUST00000141101.1
Cit
citron
chr6_+_137754529 1.316 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr19_-_4928241 1.301 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr14_+_55853997 1.266 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr11_+_117266216 1.191 ENSMUST00000019038.8
Sept9
septin 9
chr6_-_54593139 1.179 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr1_-_167285110 1.122 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr6_+_124808885 1.113 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr9_-_108452377 1.054 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr3_-_104818539 1.009 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr11_+_98960412 0.999 ENSMUST00000107473.2
Rara
retinoic acid receptor, alpha
chr6_+_50110837 0.997 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr17_-_32388885 0.982 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr1_-_118982551 0.970 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr1_+_134037490 0.934 ENSMUST00000162779.1
Fmod
fibromodulin
chr1_-_184033998 0.926 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr5_-_124354671 0.921 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_+_108920342 0.910 ENSMUST00000052915.7
Axin2
axin2
chr12_-_17176888 0.908 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr7_-_127615208 0.904 ENSMUST00000122066.1
Zfp629
zinc finger protein 629
chr11_+_62820469 0.900 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr11_-_102819663 0.883 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr4_+_128654686 0.881 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr19_+_55898553 0.880 ENSMUST00000148666.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr4_-_35845204 0.840 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr6_+_83137089 0.824 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr7_+_128237357 0.813 ENSMUST00000044660.5
Armc5
armadillo repeat containing 5
chr3_+_90072641 0.809 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr2_+_16356294 0.806 ENSMUST00000028081.6
Plxdc2
plexin domain containing 2
chr3_+_127791374 0.805 ENSMUST00000171621.1
Tifa
TRAF-interacting protein with forkhead-associated domain
chr7_-_4164796 0.742 ENSMUST00000076831.6
Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr10_+_75589363 0.718 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr14_-_49525840 0.700 ENSMUST00000138884.1
ENSMUST00000074368.4
ENSMUST00000123534.1
Slc35f4


solute carrier family 35, member F4


chr1_-_45503282 0.673 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr6_-_39557830 0.659 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr3_-_89338005 0.651 ENSMUST00000029674.7
Efna4
ephrin A4
chr10_+_128225830 0.580 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr7_-_4164442 0.575 ENSMUST00000140410.1
ENSMUST00000143825.1
Cdc42ep5

CDC42 effector protein (Rho GTPase binding) 5

chr6_-_99028874 0.556 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr10_+_19591949 0.553 ENSMUST00000020188.6
Ifngr1
interferon gamma receptor 1
chr16_-_36666067 0.551 ENSMUST00000089620.4
Cd86
CD86 antigen
chr17_+_69383319 0.547 ENSMUST00000062369.7
Zbtb14
zinc finger and BTB domain containing 14
chr2_-_79456750 0.511 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr7_-_127615226 0.503 ENSMUST00000084564.3
Zfp629
zinc finger protein 629
chr2_-_84886692 0.461 ENSMUST00000054514.5
ENSMUST00000151799.1
Rtn4rl2

reticulon 4 receptor-like 2

chr5_+_65131184 0.438 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr3_-_79145875 0.434 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr11_+_23666479 0.431 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr2_+_3118407 0.429 ENSMUST00000091505.4
Fam171a1
family with sequence similarity 171, member A1
chr3_+_107595031 0.428 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr11_-_23665862 0.395 ENSMUST00000020523.3
Pex13
peroxisomal biogenesis factor 13
chr7_-_128237984 0.385 ENSMUST00000078816.3
9130023H24Rik
RIKEN cDNA 9130023H24 gene
chr15_+_82147238 0.379 ENSMUST00000023100.6
Srebf2
sterol regulatory element binding factor 2
chr2_+_3118335 0.375 ENSMUST00000115099.2
Fam171a1
family with sequence similarity 171, member A1
chr19_+_46396885 0.367 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
Sufu


suppressor of fused homolog (Drosophila)


chr3_-_90465858 0.366 ENSMUST00000029540.6
Npr1
natriuretic peptide receptor 1
chr19_+_8617991 0.366 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr17_+_69383024 0.353 ENSMUST00000112674.1
Zbtb14
zinc finger and BTB domain containing 14
chrX_+_159459125 0.341 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
Map7d2


MAP7 domain containing 2


chr19_+_46397009 0.310 ENSMUST00000118440.1
Sufu
suppressor of fused homolog (Drosophila)
chr6_-_99028251 0.285 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr9_-_67539392 0.275 ENSMUST00000039662.8
Tln2
talin 2
chr9_-_72111651 0.265 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr18_+_65582390 0.265 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr1_-_156718989 0.258 ENSMUST00000122424.1
Fam20b
family with sequence similarity 20, member B
chr9_+_44334685 0.240 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr5_-_136883115 0.223 ENSMUST00000057497.6
ENSMUST00000111103.1
Col26a1

collagen, type XXVI, alpha 1

chr10_-_7792795 0.218 ENSMUST00000065124.1
6530403G13Rik
RIKEN cDNA 6530403G13 gene
chr11_-_95310186 0.190 ENSMUST00000103159.3
ENSMUST00000107734.3
ENSMUST00000107733.3
Kat7


K(lysine) acetyltransferase 7


chr4_+_109343029 0.188 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr1_+_133246092 0.173 ENSMUST00000038295.8
ENSMUST00000105082.2
Plekha6

pleckstrin homology domain containing, family A member 6

chr1_-_156718894 0.166 ENSMUST00000086153.6
Fam20b
family with sequence similarity 20, member B
chr9_-_72111827 0.162 ENSMUST00000183404.1
ENSMUST00000184783.1
Tcf12

transcription factor 12

chr14_-_54653616 0.159 ENSMUST00000126166.1
ENSMUST00000141453.1
ENSMUST00000150371.1
ENSMUST00000123875.1
ENSMUST00000022794.7
ENSMUST00000148754.3
Acin1





apoptotic chromatin condensation inducer 1





chr9_-_72111755 0.147 ENSMUST00000183492.1
ENSMUST00000184523.1
ENSMUST00000034755.6
Tcf12


transcription factor 12


chr7_-_27228605 0.147 ENSMUST00000003850.7
Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr18_+_56432116 0.138 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr9_-_58555129 0.130 ENSMUST00000165365.1
Cd276
CD276 antigen
chr2_-_32424005 0.118 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr9_+_21165714 0.091 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr15_-_76199835 0.082 ENSMUST00000054449.7
ENSMUST00000169714.1
ENSMUST00000165453.1
Plec


plectin


chr2_-_93046053 0.062 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chr7_+_4690604 0.040 ENSMUST00000120836.1
Brsk1
BR serine/threonine kinase 1
chr2_-_84743655 0.024 ENSMUST00000181711.1
Gm19426
predicted gene, 19426

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.0 3.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.7 2.1 GO:0097350 neutrophil clearance(GO:0097350)
0.7 2.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.5 7.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.5 2.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 1.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 1.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.3 1.5 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 0.9 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.3 0.9 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2 1.0 GO:0060032 notochord regression(GO:0060032)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.7 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 1.3 GO:0015074 DNA integration(GO:0015074)
0.1 1.6 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.5 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.4 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.9 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.8 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.4 GO:0090370 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) negative regulation of cholesterol efflux(GO:0090370)
0.1 1.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.0 1.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.0 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.7 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.4 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.9 GO:0003170 heart valve development(GO:0003170)
0.0 0.5 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.1 6.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.1 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.2 GO:0031105 septin complex(GO:0031105)
0.1 1.0 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 4.3 GO:0005882 intermediate filament(GO:0005882)
0.1 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 6.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 1.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 0.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 0.9 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.2 1.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 7.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 4.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 6.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.4 GO:0001653 peptide receptor activity(GO:0001653)
0.1 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.0 GO:0035014 retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.9 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.6 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 3.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.9 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 7.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 1.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 6.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.9 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.1 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels