Motif ID: Atf7_E4f1
Z-value: 1.561


Transcription factors associated with Atf7_E4f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atf7 | ENSMUSG00000052414.9 | Atf7 |
Atf7 | ENSMUSG00000071584.1 | Atf7 |
E4f1 | ENSMUSG00000024137.8 | E4f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Atf7 | mm10_v2_chr15_-_102529025_102529025 | -0.74 | 3.9e-04 | Click! |
E4f1 | mm10_v2_chr17_-_24455265_24455345 | -0.55 | 1.8e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 12.7 | GO:0046490 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490) |
1.9 | 7.6 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
1.7 | 10.2 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
1.3 | 1.3 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
1.3 | 3.9 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
1.3 | 3.9 | GO:0072284 | cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
1.2 | 3.6 | GO:0014028 | notochord formation(GO:0014028) |
1.1 | 6.7 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.1 | 6.6 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.9 | 4.6 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.9 | 5.4 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.8 | 3.2 | GO:0060578 | extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
0.8 | 9.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.7 | 2.0 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044) |
0.7 | 2.7 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
0.7 | 3.3 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
0.6 | 1.9 | GO:0035973 | aggrephagy(GO:0035973) |
0.6 | 2.5 | GO:0090467 | L-arginine import(GO:0043091) arginine import(GO:0090467) |
0.6 | 1.8 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.6 | 4.1 | GO:0098535 | positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535) |
0.6 | 5.3 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.6 | 2.8 | GO:0051309 | female meiosis chromosome separation(GO:0051309) |
0.5 | 2.7 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
0.5 | 10.3 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.5 | 6.4 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
0.5 | 1.6 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
0.5 | 5.2 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.5 | 1.9 | GO:1902990 | leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
0.5 | 3.8 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.5 | 1.9 | GO:0021986 | epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866) |
0.5 | 5.2 | GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030) |
0.5 | 5.5 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.4 | 3.1 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.4 | 2.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.4 | 2.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.4 | 4.4 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
0.4 | 1.9 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.4 | 1.1 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.4 | 2.6 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
0.4 | 1.1 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.4 | 1.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.3 | 0.7 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.3 | 2.0 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.3 | 1.0 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.3 | 1.6 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.3 | 1.3 | GO:1902724 | positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
0.3 | 2.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.3 | 1.5 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
0.3 | 2.1 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
0.3 | 1.5 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
0.3 | 0.9 | GO:0051030 | snRNA transport(GO:0051030) |
0.3 | 2.0 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.3 | 3.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.3 | 0.8 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.3 | 0.8 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
0.3 | 0.8 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
0.3 | 3.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.2 | 0.7 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.2 | 0.7 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
0.2 | 0.7 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.2 | 6.7 | GO:0034508 | centromere complex assembly(GO:0034508) |
0.2 | 1.6 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.2 | 0.7 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
0.2 | 1.4 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.2 | 1.3 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
0.2 | 0.9 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.2 | 1.1 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.2 | 7.8 | GO:0001709 | cell fate determination(GO:0001709) |
0.2 | 1.1 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
0.2 | 2.5 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.2 | 0.8 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
0.2 | 4.3 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.2 | 0.6 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.2 | 0.8 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.2 | 2.3 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.2 | 1.7 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.2 | 0.9 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.2 | 0.6 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
0.2 | 0.7 | GO:2000319 | negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
0.2 | 0.9 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.2 | 2.4 | GO:0031639 | plasminogen activation(GO:0031639) |
0.2 | 0.9 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.2 | 2.7 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.2 | 3.7 | GO:0007530 | sex determination(GO:0007530) |
0.2 | 1.3 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
0.2 | 0.2 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
0.2 | 1.2 | GO:0051036 | regulation of endosome size(GO:0051036) |
0.2 | 0.5 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.2 | 0.8 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 2.2 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.1 | 0.4 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
0.1 | 1.4 | GO:0030049 | muscle filament sliding(GO:0030049) |
0.1 | 0.4 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.1 | 0.4 | GO:0031038 | myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) |
0.1 | 0.5 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.1 | 1.5 | GO:1990403 | embryonic brain development(GO:1990403) |
0.1 | 0.6 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.1 | 0.6 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.1 | 4.9 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.1 | 2.5 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.1 | 0.8 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 0.5 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
0.1 | 0.5 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
0.1 | 0.8 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 0.8 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.1 | 1.6 | GO:0042407 | cristae formation(GO:0042407) |
0.1 | 0.9 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
0.1 | 0.9 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.1 | 0.3 | GO:0030070 | insulin processing(GO:0030070) |
0.1 | 1.7 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.1 | 1.7 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 0.5 | GO:0044828 | negative regulation by host of viral process(GO:0044793) negative regulation by host of viral genome replication(GO:0044828) |
0.1 | 0.8 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.1 | 1.0 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.5 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.1 | 3.8 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.1 | 0.9 | GO:0030432 | peristalsis(GO:0030432) |
0.1 | 1.0 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
0.1 | 0.6 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 3.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.4 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.1 | 0.6 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
0.1 | 0.4 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 3.8 | GO:0009409 | response to cold(GO:0009409) |
0.1 | 0.3 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.1 | 0.6 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.1 | 0.9 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.1 | 0.5 | GO:0048539 | bone marrow development(GO:0048539) |
0.1 | 2.2 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.1 | 0.8 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 0.5 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.1 | 1.4 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.1 | 0.5 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
0.1 | 0.9 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.1 | 1.4 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.1 | 1.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.1 | 3.1 | GO:0035082 | axoneme assembly(GO:0035082) |
0.1 | 1.0 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.1 | 0.6 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.1 | 0.8 | GO:0019985 | translesion synthesis(GO:0019985) |
0.1 | 0.2 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.1 | 0.6 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.1 | 1.2 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.1 | 3.3 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.1 | 0.9 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
0.1 | 1.5 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.1 | 1.9 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.1 | 0.3 | GO:1903232 | melanosome assembly(GO:1903232) |
0.1 | 0.1 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
0.1 | 1.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.1 | 6.1 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.1 | 0.3 | GO:0035553 | oxidative single-stranded RNA demethylation(GO:0035553) |
0.1 | 0.8 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.1 | 0.2 | GO:0033108 | mitochondrial respiratory chain complex assembly(GO:0033108) |
0.1 | 0.3 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.1 | 5.3 | GO:0006342 | chromatin silencing(GO:0006342) |
0.1 | 0.6 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
0.1 | 0.5 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
0.1 | 0.3 | GO:0031442 | positive regulation of mRNA 3'-end processing(GO:0031442) |
0.1 | 0.2 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
0.0 | 1.1 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.0 | 0.6 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
0.0 | 0.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 1.3 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 1.4 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 1.3 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.0 | 0.2 | GO:0030223 | neutrophil differentiation(GO:0030223) |
0.0 | 0.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
0.0 | 0.5 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.5 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
0.0 | 0.8 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.6 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
0.0 | 1.2 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.6 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.5 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
0.0 | 1.9 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.0 | 0.5 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.0 | 0.3 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.0 | 0.6 | GO:0031670 | cellular response to nutrient(GO:0031670) |
0.0 | 1.3 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 0.2 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.0 | 0.4 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.0 | 0.6 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
0.0 | 2.1 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
0.0 | 0.5 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
0.0 | 0.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.1 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 1.4 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.1 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
0.0 | 0.6 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.0 | 0.4 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.0 | 0.6 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.0 | 1.5 | GO:0051225 | spindle assembly(GO:0051225) |
0.0 | 0.2 | GO:0071028 | RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
0.0 | 0.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.0 | 1.8 | GO:0042254 | ribosome biogenesis(GO:0042254) |
0.0 | 0.3 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.6 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.4 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.0 | 8.3 | GO:0006412 | translation(GO:0006412) |
0.0 | 0.5 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
0.0 | 0.1 | GO:0070344 | fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345) |
0.0 | 5.6 | GO:0008380 | RNA splicing(GO:0008380) |
0.0 | 2.0 | GO:0048864 | stem cell development(GO:0048864) |
0.0 | 0.6 | GO:0006352 | DNA-templated transcription, initiation(GO:0006352) |
0.0 | 0.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.2 | GO:0034063 | stress granule assembly(GO:0034063) |
0.0 | 0.2 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
0.0 | 2.0 | GO:0030336 | negative regulation of cell migration(GO:0030336) |
0.0 | 0.1 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
0.0 | 0.4 | GO:0051591 | response to cAMP(GO:0051591) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.0 | 6.1 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
1.3 | 9.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.8 | 3.3 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
0.7 | 4.1 | GO:0098536 | deuterosome(GO:0098536) |
0.7 | 2.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.6 | 1.9 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.6 | 10.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.6 | 1.9 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.6 | 6.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.6 | 9.3 | GO:0030008 | TRAPP complex(GO:0030008) |
0.6 | 4.1 | GO:0001940 | male pronucleus(GO:0001940) |
0.5 | 1.6 | GO:0000799 | nuclear condensin complex(GO:0000799) |
0.5 | 2.0 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.5 | 3.3 | GO:0010009 | cytoplasmic side of endosome membrane(GO:0010009) |
0.4 | 2.5 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.4 | 5.7 | GO:0016589 | NURF complex(GO:0016589) |
0.4 | 3.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.4 | 1.5 | GO:0000939 | nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939) |
0.4 | 1.8 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
0.3 | 17.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.3 | 9.9 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.3 | 1.5 | GO:0030689 | Noc complex(GO:0030689) |
0.3 | 12.1 | GO:0097546 | ciliary base(GO:0097546) |
0.3 | 1.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.3 | 1.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.3 | 1.9 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.3 | 2.5 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.2 | 2.0 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.2 | 1.3 | GO:0000125 | PCAF complex(GO:0000125) |
0.2 | 0.9 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.2 | 1.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.2 | 1.6 | GO:0070652 | HAUS complex(GO:0070652) |
0.2 | 1.8 | GO:0061617 | MICOS complex(GO:0061617) |
0.2 | 1.7 | GO:0089701 | U2AF(GO:0089701) |
0.2 | 0.9 | GO:1990246 | uniplex complex(GO:1990246) |
0.2 | 2.1 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.2 | 2.2 | GO:0071437 | invadopodium(GO:0071437) |
0.2 | 1.2 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.2 | 1.1 | GO:0000796 | condensin complex(GO:0000796) |
0.2 | 4.7 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.2 | 2.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.2 | 2.4 | GO:0031011 | Ino80 complex(GO:0031011) |
0.2 | 1.1 | GO:0033503 | HULC complex(GO:0033503) |
0.2 | 2.6 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 10.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 3.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.1 | 0.5 | GO:0097447 | dendritic tree(GO:0097447) |
0.1 | 0.8 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.1 | 1.4 | GO:0016461 | unconventional myosin complex(GO:0016461) |
0.1 | 3.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.1 | 1.6 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.1 | 2.0 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.1 | 0.6 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.1 | 0.7 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 3.6 | GO:0044815 | DNA packaging complex(GO:0044815) |
0.1 | 1.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 0.6 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.1 | 2.8 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.1 | 0.3 | GO:0042827 | platelet dense granule(GO:0042827) |
0.1 | 3.6 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.1 | 1.0 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 4.4 | GO:0015934 | large ribosomal subunit(GO:0015934) |
0.1 | 1.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.1 | 1.1 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 0.4 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 9.7 | GO:0000776 | kinetochore(GO:0000776) |
0.1 | 0.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 12.5 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 3.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 3.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 0.8 | GO:0042555 | MCM complex(GO:0042555) |
0.1 | 0.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476) |
0.1 | 1.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.1 | 0.6 | GO:0001739 | sex chromatin(GO:0001739) |
0.1 | 2.2 | GO:0030286 | dynein complex(GO:0030286) |
0.1 | 0.4 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 2.0 | GO:0005876 | spindle microtubule(GO:0005876) |
0.1 | 3.3 | GO:0005844 | polysome(GO:0005844) |
0.1 | 0.8 | GO:0010369 | chromocenter(GO:0010369) |
0.1 | 0.5 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.6 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 3.4 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 2.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.6 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.6 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
0.0 | 0.2 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.0 | 1.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 2.6 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 1.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.4 | GO:0005685 | U1 snRNP(GO:0005685) |
0.0 | 8.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 1.6 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.9 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 7.7 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 1.0 | GO:0031514 | motile cilium(GO:0031514) |
0.0 | 2.4 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.8 | GO:0005840 | ribosome(GO:0005840) |
0.0 | 0.6 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.3 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 0.8 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 0.1 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.8 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.0 | 0.6 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 0.8 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 1.4 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 0.2 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.2 | GO:0030686 | 90S preribosome(GO:0030686) |
0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 3.9 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 1.9 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.6 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 1.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 3.8 | GO:0005739 | mitochondrion(GO:0005739) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 7.6 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.8 | 2.5 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.8 | 6.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.7 | 3.6 | GO:0032027 | myosin light chain binding(GO:0032027) |
0.7 | 10.2 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.7 | 2.0 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
0.6 | 1.9 | GO:0032139 | DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139) |
0.6 | 1.9 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.6 | 1.8 | GO:0070052 | collagen V binding(GO:0070052) |
0.6 | 2.4 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.5 | 4.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.5 | 2.1 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.5 | 3.9 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.5 | 1.4 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
0.5 | 2.7 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.4 | 5.5 | GO:0001618 | virus receptor activity(GO:0001618) |
0.4 | 1.7 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
0.4 | 6.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.4 | 2.5 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.4 | 5.2 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.4 | 9.1 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.4 | 1.1 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.4 | 1.8 | GO:0043515 | kinetochore binding(GO:0043515) |
0.3 | 2.0 | GO:0045340 | mercury ion binding(GO:0045340) |
0.3 | 0.9 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.3 | 1.2 | GO:0042731 | PH domain binding(GO:0042731) |
0.3 | 1.4 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.3 | 0.8 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.3 | 1.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.3 | 3.1 | GO:0031996 | thioesterase binding(GO:0031996) |
0.2 | 0.5 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.2 | 1.7 | GO:0050733 | RS domain binding(GO:0050733) |
0.2 | 1.2 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.2 | 2.0 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.2 | 1.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.2 | 0.9 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.2 | 3.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.2 | 0.6 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.2 | 0.7 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.2 | 1.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.2 | 3.0 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.2 | 3.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.2 | 0.5 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.2 | 3.0 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.2 | 1.8 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.2 | 7.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.2 | 1.5 | GO:0032564 | dATP binding(GO:0032564) |
0.2 | 1.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.2 | 1.3 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.2 | 0.5 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.2 | 0.9 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.2 | 0.9 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.2 | 5.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.2 | 2.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.2 | 0.6 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.1 | 2.0 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.1 | 5.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 3.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.1 | 0.5 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
0.1 | 0.7 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 0.4 | GO:0030519 | snoRNP binding(GO:0030519) |
0.1 | 21.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.1 | 2.0 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.1 | 6.1 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
0.1 | 2.7 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.1 | 2.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 1.6 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.1 | 5.5 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
0.1 | 1.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.1 | 0.6 | GO:0043426 | MRF binding(GO:0043426) |
0.1 | 0.5 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 0.4 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.1 | 0.6 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.1 | 1.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.1 | 2.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 2.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 1.0 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 3.3 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.1 | 0.5 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 3.6 | GO:0009055 | electron carrier activity(GO:0009055) |
0.1 | 1.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.1 | 0.8 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.9 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 0.6 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.1 | 2.1 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.1 | 1.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 1.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.1 | 0.3 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.1 | 0.6 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
0.1 | 1.4 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 0.6 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.1 | 2.0 | GO:0019843 | rRNA binding(GO:0019843) |
0.1 | 1.1 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 3.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 0.9 | GO:0070717 | poly-purine tract binding(GO:0070717) |
0.1 | 1.4 | GO:0030515 | snoRNA binding(GO:0030515) |
0.1 | 0.6 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.1 | 0.2 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
0.1 | 9.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.2 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.1 | 2.7 | GO:0004497 | monooxygenase activity(GO:0004497) |
0.0 | 3.9 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 0.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.3 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.0 | 0.5 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.5 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 2.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 0.3 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
0.0 | 0.1 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
0.0 | 0.3 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.0 | 0.6 | GO:0048156 | tau protein binding(GO:0048156) |
0.0 | 2.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
0.0 | 2.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.6 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.0 | 0.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 2.7 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.1 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
0.0 | 0.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.7 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.0 | 0.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 2.0 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.6 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 5.4 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.4 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.2 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
0.0 | 0.9 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 1.3 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.1 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
0.0 | 0.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.6 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 1.2 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.0 | 1.0 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.0 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858) |
0.0 | 1.7 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.0 | 0.8 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 1.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 1.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 1.3 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 0.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.4 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.4 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 0.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 7.1 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.2 | 2.0 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.2 | 3.9 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.2 | 2.8 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 3.6 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.1 | 6.1 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 3.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 4.2 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.1 | 1.3 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.1 | 3.2 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.1 | 1.7 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.1 | 1.8 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.1 | 3.6 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.1 | 2.6 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
0.1 | 5.0 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.1 | 1.3 | PID_MYC_PATHWAY | C-MYC pathway |
0.1 | 2.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.1 | 0.6 | PID_FOXO_PATHWAY | FoxO family signaling |
0.1 | 2.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.2 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.0 | 3.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 1.5 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 0.9 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 0.8 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.0 | 0.5 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 1.2 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.3 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.3 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.6 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
0.0 | 0.6 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 0.4 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 9.1 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.5 | 12.6 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.3 | 12.3 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.3 | 17.7 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.3 | 6.6 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.2 | 4.1 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.2 | 3.3 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.2 | 2.0 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.2 | 1.9 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.2 | 4.8 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.2 | 10.9 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.1 | 2.0 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.1 | 1.5 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.1 | 1.6 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.1 | 0.5 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 3.2 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.1 | 3.2 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 1.8 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 3.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.1 | 2.0 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 7.6 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.1 | 3.1 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.1 | 1.3 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.1 | 4.6 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.1 | 8.0 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 0.6 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.1 | 5.3 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.1 | 1.1 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.1 | 2.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.1 | 1.1 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
0.1 | 1.1 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 2.5 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.1 | 0.9 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
0.1 | 2.4 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.1 | 1.4 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.1 | 7.7 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.1 | 5.2 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.1 | 1.9 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.1 | 1.4 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 0.8 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.1 | 0.8 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.1 | 1.0 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.1 | 0.6 | REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
0.0 | 0.9 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.0 | 2.1 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.9 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 1.6 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 1.0 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 1.2 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 1.1 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.8 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.0 | 0.4 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 0.6 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 1.8 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 0.4 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.0 | 0.5 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
0.0 | 0.8 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 0.5 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.6 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.5 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 1.6 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.1 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.0 | 0.5 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 1.8 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.4 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.6 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
0.0 | 3.3 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.5 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.0 | 0.3 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.6 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.2 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.3 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.0 | 0.4 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |