Motif ID: Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Z-value: 1.027


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mlxmm10_v2_chr11_+_101087277_101087323-0.736.4e-04Click!
Arntlmm10_v2_chr7_+_113207465_113207595-0.581.3e-02Click!
Tfe3mm10_v2_chrX_+_7762652_7762695-0.371.3e-01Click!
Mlxiplmm10_v2_chr5_+_135106881_135106918-0.077.9e-01Click!
Mitfmm10_v2_chr6_+_97807014_97807067-0.009.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_127063599 5.100 ENSMUST00000120226.1
ENSMUST00000133115.1
Cdk4

cyclin-dependent kinase 4

chr19_-_4201591 4.601 ENSMUST00000025740.6
Rad9a
RAD9 homolog A
chr10_+_127063527 4.547 ENSMUST00000006911.5
Cdk4
cyclin-dependent kinase 4
chr11_+_70000578 3.907 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr3_+_137864573 3.328 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr10_-_128923948 3.136 ENSMUST00000131271.1
Bloc1s1
biogenesis of lysosome-related organelles complex-1, subunit 1
chr5_+_99979061 3.104 ENSMUST00000046721.1
4930524J08Rik
RIKEN cDNA 4930524J08 gene
chr7_-_45466894 2.977 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr2_+_121449362 2.974 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr17_-_26939464 2.846 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr3_+_137864487 2.843 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr5_-_137314175 2.841 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chr3_+_90052814 2.718 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
4933434E20Rik



RIKEN cDNA 4933434E20 gene



chrX_-_134600976 2.682 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr6_+_108660616 2.523 ENSMUST00000032194.4
Bhlhe40
basic helix-loop-helix family, member e40
chr10_-_128923439 2.506 ENSMUST00000153731.1
ENSMUST00000026405.3
Bloc1s1

biogenesis of lysosome-related organelles complex-1, subunit 1

chr10_-_128922888 2.490 ENSMUST00000135161.1
Rdh5
retinol dehydrogenase 5
chrX_+_134601179 2.443 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr11_+_69935894 2.267 ENSMUST00000149194.1
Ybx2
Y box protein 2
chr10_+_41519493 2.243 ENSMUST00000019962.8
Cd164
CD164 antigen
chr2_+_164833841 2.141 ENSMUST00000152721.1
Ctsa
cathepsin A
chr15_+_34238026 2.075 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr9_+_102626278 2.040 ENSMUST00000038673.7
Anapc13
anaphase promoting complex subunit 13
chr2_-_79456750 2.007 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr14_-_118052235 1.994 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr11_+_69935796 1.981 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr19_-_10203880 1.974 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chrX_+_134601271 1.964 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr11_-_94653964 1.949 ENSMUST00000039949.4
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_+_164833781 1.912 ENSMUST00000143780.1
Ctsa
cathepsin A
chr15_+_59374198 1.904 ENSMUST00000079703.3
ENSMUST00000168722.1
Nsmce2

non-SMC element 2 homolog (MMS21, S. cerevisiae)

chrX_+_136270302 1.894 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrY_-_1245685 1.867 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr17_+_56040350 1.865 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr2_+_75659253 1.789 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr3_+_159495408 1.771 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a


DEP domain containing 1a


chrX_+_136270253 1.762 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr19_-_7241216 1.758 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr10_-_62486772 1.739 ENSMUST00000105447.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr8_+_75093591 1.644 ENSMUST00000005548.6
Hmox1
heme oxygenase (decycling) 1
chr11_-_52000432 1.630 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr6_+_134929118 1.629 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr4_+_128654686 1.617 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr11_+_95337012 1.614 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr17_-_24163668 1.599 ENSMUST00000040735.5
Amdhd2
amidohydrolase domain containing 2
chr6_+_134929089 1.594 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr7_-_105752193 1.577 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr2_+_84839395 1.565 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr1_+_166254095 1.551 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr13_+_55321991 1.539 ENSMUST00000021942.6
Prelid1
PRELI domain containing 1
chr9_+_21411824 1.514 ENSMUST00000002902.6
Qtrt1
queuine tRNA-ribosyltransferase 1
chr8_+_13159135 1.492 ENSMUST00000033824.6
Lamp1
lysosomal-associated membrane protein 1
chr4_+_129336012 1.455 ENSMUST00000119480.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr3_+_67582737 1.439 ENSMUST00000029344.8
Mfsd1
major facilitator superfamily domain containing 1
chr4_-_116994374 1.437 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr11_-_120549695 1.427 ENSMUST00000034913.4
Fam195b
family with sequence similarity 195, member B
chr3_-_37724321 1.418 ENSMUST00000108105.1
ENSMUST00000079755.4
ENSMUST00000099128.1
Gm5148


predicted gene 5148


chr19_-_4615647 1.414 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr18_+_53176345 1.407 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr7_-_116308241 1.404 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
Plekha7


pleckstrin homology domain containing, family A member 7


chrX_-_136215443 1.395 ENSMUST00000113120.1
ENSMUST00000113118.1
ENSMUST00000058125.8
Bex1


brain expressed gene 1


chr1_-_75219245 1.394 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr8_+_75033673 1.376 ENSMUST00000078847.5
ENSMUST00000165630.1
Tom1

target of myb1 homolog (chicken)

chr14_-_50930803 1.361 ENSMUST00000160538.1
ENSMUST00000162957.1
ENSMUST00000161166.1
ENSMUST00000160835.1
ENSMUST00000049312.7
Tmem55b




transmembrane protein 55b




chr2_-_25356319 1.339 ENSMUST00000028332.7
Dpp7
dipeptidylpeptidase 7
chrY_-_1245753 1.339 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr2_-_28466266 1.328 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr11_+_94653767 1.318 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr17_-_33685386 1.309 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm


heterogeneous nuclear ribonucleoprotein M


chr12_-_74316394 1.307 ENSMUST00000110441.1
Gm11042
predicted gene 11042
chr17_-_12769605 1.305 ENSMUST00000024599.7
Igf2r
insulin-like growth factor 2 receptor
chr10_-_62486575 1.298 ENSMUST00000092473.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr17_-_56609689 1.295 ENSMUST00000052832.5
2410015M20Rik
RIKEN cDNA 2410015M20 gene
chr16_+_45158725 1.290 ENSMUST00000023343.3
Atg3
autophagy related 3
chr7_+_127841752 1.280 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr6_-_72235559 1.268 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr9_-_103480328 1.264 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr19_-_4615453 1.260 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr7_-_126377401 1.246 ENSMUST00000119846.1
ENSMUST00000119754.1
ENSMUST00000032994.8
Spns1


spinster homolog 1


chr6_-_128362812 1.242 ENSMUST00000112152.1
ENSMUST00000057421.8
ENSMUST00000112151.1
Rhno1


RAD9-HUS1-RAD1 interacting nuclear orphan 1


chr11_+_69991061 1.228 ENSMUST00000018711.8
Gabarap
gamma-aminobutyric acid receptor associated protein
chr5_+_128601106 1.218 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr8_+_119575235 1.207 ENSMUST00000093100.2
Dnaaf1
dynein, axonemal assembly factor 1
chr17_-_33824346 1.194 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr4_-_116994354 1.189 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chrX_-_136068236 1.173 ENSMUST00000049130.7
Bex2
brain expressed X-linked 2
chr9_+_21368014 1.165 ENSMUST00000067646.4
ENSMUST00000115414.1
Ilf3

interleukin enhancer binding factor 3

chr1_+_17727034 1.165 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr4_-_55532453 1.163 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr2_+_92915080 1.160 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr4_-_129239165 1.149 ENSMUST00000097873.3
C77080
expressed sequence C77080
chr19_-_8786272 1.148 ENSMUST00000176610.1
ENSMUST00000177056.1
Taf6l

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

chr9_-_106887000 1.146 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr11_-_97782409 1.133 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr13_+_37826225 1.132 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr11_-_52000748 1.128 ENSMUST00000109086.1
Ube2b
ubiquitin-conjugating enzyme E2B
chr1_-_82291370 1.114 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr11_+_116198853 1.114 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr7_+_127841817 1.113 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr4_-_129578535 1.112 ENSMUST00000052835.8
Fam167b
family with sequence similarity 167, member B
chr5_+_115011111 1.110 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chrX_-_136172195 1.108 ENSMUST00000136533.1
ENSMUST00000146583.1
Tceal8

transcription elongation factor A (SII)-like 8

chrX_-_60893430 1.102 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr1_-_75142360 1.097 ENSMUST00000041213.5
Cnppd1
cyclin Pas1/PHO80 domain containing 1
chr4_-_148087961 1.095 ENSMUST00000030865.8
Agtrap
angiotensin II, type I receptor-associated protein
chr11_-_58801944 1.094 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr5_+_28165690 1.086 ENSMUST00000036177.7
En2
engrailed 2
chr9_+_35267857 1.077 ENSMUST00000034543.4
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr13_-_119408985 1.065 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr18_+_75367529 1.060 ENSMUST00000026999.3
Smad7
SMAD family member 7
chrX_+_136138996 1.054 ENSMUST00000116527.1
Bex4
brain expressed gene 4
chr19_+_10204014 1.049 ENSMUST00000040372.7
Tmem258
transmembrane protein 258
chr19_-_8786245 1.048 ENSMUST00000177216.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr9_+_108339048 1.044 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr15_+_79030874 1.043 ENSMUST00000171999.1
ENSMUST00000006544.7
Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

chr3_+_89773562 1.042 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr4_-_117887292 1.038 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr14_-_50924626 1.032 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
Osgep


O-sialoglycoprotein endopeptidase


chr12_+_17544873 1.027 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr3_-_108226598 1.026 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr2_+_168081004 1.014 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr4_+_123917420 1.014 ENSMUST00000030399.6
Rragc
Ras-related GTP binding C
chr19_+_41981709 1.011 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr7_+_101905837 0.987 ENSMUST00000033131.6
Lamtor1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr3_+_104638658 0.980 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr9_-_102626509 0.975 ENSMUST00000161645.1
ENSMUST00000162297.1
ENSMUST00000162655.1
Cep63


centrosomal protein 63


chr5_+_104046869 0.973 ENSMUST00000031250.7
Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr2_+_156840966 0.970 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr3_-_90052463 0.965 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
Ubap2l


ubiquitin associated protein 2-like


chr8_-_122432924 0.963 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr12_-_59219725 0.963 ENSMUST00000043204.7
Fbxo33
F-box protein 33
chr11_-_3931960 0.961 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr6_+_85187438 0.953 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr10_+_128322443 0.947 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr11_-_117780630 0.947 ENSMUST00000026659.3
ENSMUST00000127227.1
Tmc6

transmembrane channel-like gene family 6

chr11_+_102881204 0.934 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr5_+_104046980 0.931 ENSMUST00000134313.1
Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chrX_-_136172233 0.931 ENSMUST00000163584.1
ENSMUST00000060101.3
Tceal8

transcription elongation factor A (SII)-like 8

chr11_-_3931789 0.927 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr4_-_137048695 0.926 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr5_-_99978914 0.919 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr13_-_55321928 0.914 ENSMUST00000035242.7
Rab24
RAB24, member RAS oncogene family
chr3_-_79842662 0.911 ENSMUST00000029568.1
Tmem144
transmembrane protein 144
chr17_+_45563928 0.908 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chr17_+_24632671 0.904 ENSMUST00000047611.2
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr15_+_102279446 0.903 ENSMUST00000051341.4
Mfsd5
major facilitator superfamily domain containing 5
chr11_-_60811228 0.895 ENSMUST00000018744.8
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr9_-_102626095 0.893 ENSMUST00000093791.3
Cep63
centrosomal protein 63
chr7_-_45128725 0.887 ENSMUST00000150350.1
Rpl13a
ribosomal protein L13A
chr2_+_31572651 0.887 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr10_+_77606044 0.880 ENSMUST00000020501.8
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr8_-_84846860 0.879 ENSMUST00000003912.6
Calr
calreticulin
chr10_-_63339023 0.874 ENSMUST00000177694.1
ENSMUST00000020257.6
ENSMUST00000105442.2
Sirt1


sirtuin 1


chr9_+_3037111 0.873 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr10_+_4432467 0.871 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
1700052N19Rik


RIKEN cDNA 1700052N19 gene


chr3_-_96727436 0.862 ENSMUST00000154679.1
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr10_+_22158566 0.861 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr16_-_94370994 0.858 ENSMUST00000113914.1
ENSMUST00000113905.1
Pigp

phosphatidylinositol glycan anchor biosynthesis, class P

chr11_+_69913888 0.855 ENSMUST00000072581.2
ENSMUST00000116358.1
Gps2

G protein pathway suppressor 2

chr4_-_141053660 0.855 ENSMUST00000040222.7
Crocc
ciliary rootlet coiled-coil, rootletin
chr1_+_191098414 0.849 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr13_+_108316332 0.848 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr7_-_141214080 0.847 ENSMUST00000026573.5
ENSMUST00000170841.1
1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr10_+_77606571 0.847 ENSMUST00000099538.5
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr3_-_96727566 0.847 ENSMUST00000029741.2
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr11_-_102230091 0.846 ENSMUST00000008999.5
Hdac5
histone deacetylase 5
chr11_-_94242701 0.844 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr6_-_108185552 0.838 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr2_+_31572701 0.836 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3
chr6_+_128362919 0.834 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr4_-_129335324 0.833 ENSMUST00000102598.3
Rbbp4
retinoblastoma binding protein 4
chr14_+_50924968 0.831 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
Apex1


apurinic/apyrimidinic endonuclease 1


chr7_-_16387791 0.830 ENSMUST00000094815.3
Sae1
SUMO1 activating enzyme subunit 1
chr5_-_72168142 0.826 ENSMUST00000013693.6
Commd8
COMM domain containing 8
chr7_-_142387895 0.821 ENSMUST00000151120.1
Ctsd
cathepsin D
chr11_-_97782377 0.811 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr5_+_45520221 0.792 ENSMUST00000156481.1
ENSMUST00000119579.1
ENSMUST00000118833.1
Med28


mediator of RNA polymerase II transcription, subunit 28 homolog (yeast)


chr11_-_102230127 0.791 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
Hdac5



histone deacetylase 5



chr11_-_69920892 0.791 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr15_+_100615620 0.789 ENSMUST00000000356.8
Dazap2
DAZ associated protein 2
chr5_+_104046526 0.788 ENSMUST00000150226.1
Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr9_-_13826946 0.786 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr2_+_26586607 0.781 ENSMUST00000174211.1
ENSMUST00000145575.2
ENSMUST00000173920.1
Egfl7


EGF-like domain 7


chrX_+_36795642 0.780 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr4_-_134018829 0.778 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr11_+_69914179 0.777 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chr12_+_65036319 0.776 ENSMUST00000120580.1
Prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr19_-_8786408 0.771 ENSMUST00000176496.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr4_-_141053704 0.769 ENSMUST00000102491.3
Crocc
ciliary rootlet coiled-coil, rootletin
chr16_-_5203981 0.761 ENSMUST00000147567.1
ENSMUST00000023911.4
Nagpa

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chrX_+_71215006 0.757 ENSMUST00000101501.3
ENSMUST00000061970.5
ENSMUST00000025391.4
ENSMUST00000114621.1
ENSMUST00000033700.5
Mtm1




X-linked myotubular myopathy gene 1




chr2_+_30066419 0.747 ENSMUST00000067996.6
Set
SET nuclear oncogene
chr5_+_24428208 0.745 ENSMUST00000115049.2
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr19_+_34922351 0.745 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr6_+_117907795 0.743 ENSMUST00000167657.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr2_-_37703275 0.743 ENSMUST00000072186.5
Strbp
spermatid perinuclear RNA binding protein
chr7_-_27166413 0.740 ENSMUST00000108382.1
Egln2
EGL nine homolog 2 (C. elegans)
chrX_-_134541847 0.739 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr9_-_107289847 0.737 ENSMUST00000035194.2
Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr5_+_30921825 0.733 ENSMUST00000117435.1
Khk
ketohexokinase

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0010288 response to lead ion(GO:0010288)
1.0 3.0 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.9 2.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.9 2.7 GO:0046032 ADP catabolic process(GO:0046032)
0.8 2.4 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.8 3.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.7 4.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.7 2.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.6 1.9 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.6 1.8 GO:0030421 defecation(GO:0030421)
0.6 3.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.5 0.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.5 1.6 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.5 2.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.5 1.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.5 2.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.5 1.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.5 1.9 GO:0015889 cobalamin transport(GO:0015889)
0.5 6.0 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.5 0.9 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.4 2.6 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.4 1.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 3.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 1.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.4 1.2 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.4 1.9 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.4 1.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.4 3.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.4 1.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.4 1.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.3 1.0 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.3 1.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of arachidonic acid secretion(GO:0090238) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 1.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.3 1.0 GO:1901355 response to rapamycin(GO:1901355)
0.3 2.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 2.5 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.3 1.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.3 1.3 GO:0006545 glycine biosynthetic process(GO:0006545)
0.3 6.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.3 0.9 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3 0.9 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 2.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.3 1.6 GO:0032439 endosome localization(GO:0032439)
0.3 0.8 GO:0036166 phenotypic switching(GO:0036166)
0.3 1.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 6.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 1.0 GO:0070459 prolactin secretion(GO:0070459)
0.3 1.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 0.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 1.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.7 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 1.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.7 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167) regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 1.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 2.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 1.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 1.1 GO:0018158 protein oxidation(GO:0018158)
0.2 0.7 GO:1990523 bone regeneration(GO:1990523)
0.2 0.7 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 0.8 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.2 0.8 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of heart induction(GO:0090381)
0.2 1.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.2 1.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.2 0.8 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 0.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 1.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 0.7 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.2 1.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 1.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.5 GO:0071873 response to norepinephrine(GO:0071873)
0.2 0.8 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.2 2.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 0.8 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 0.8 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.2 0.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.5 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.2 0.6 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.2 0.8 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 1.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 3.6 GO:0007035 vacuolar acidification(GO:0007035)
0.2 4.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.2 0.6 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 1.0 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.4 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 1.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.7 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 1.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 1.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.6 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.1 1.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 3.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.9 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 1.4 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 1.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 0.5 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.7 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.1 0.5 GO:0015888 thiamine transport(GO:0015888)
0.1 1.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.9 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.1 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.1 0.3 GO:0030324 lung development(GO:0030324)
0.1 1.2 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.1 0.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1 0.3 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.1 0.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 4.1 GO:0048255 mRNA stabilization(GO:0048255)
0.1 0.3 GO:0046061 dATP catabolic process(GO:0046061)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.1 GO:2000643 positive regulation of vacuolar transport(GO:1903337) positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 2.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 0.2 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 1.2 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.6 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 1.4 GO:0006183 GTP biosynthetic process(GO:0006183)
0.1 0.1 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.2 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 0.4 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 0.8 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.3 GO:0009204 deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.1 0.5 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.4 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.2 GO:0042637 catagen(GO:0042637)
0.1 1.3 GO:0042407 cristae formation(GO:0042407)
0.1 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.4 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.1 1.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 1.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.5 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.3 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.8 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.2 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.4 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 0.7 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.1 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.7 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.2 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.1 0.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.7 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.8 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.1 GO:0002339 B cell selection(GO:0002339)
0.1 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.1 GO:1904170 regulation of bleb assembly(GO:1904170)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.9 GO:0060481 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1 0.1 GO:1902302 regulation of potassium ion export(GO:1902302)
0.1 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 2.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.1 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.1 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.2 GO:0007530 sex determination(GO:0007530)
0.1 0.2 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.1 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.2 GO:0048864 stem cell development(GO:0048864)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.1 GO:0043096 purine nucleobase salvage(GO:0043096)
0.1 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.1 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
0.1 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.4 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.6 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.1 1.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.4 GO:0006105 succinate metabolic process(GO:0006105)
0.1 2.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.2 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0007521 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) muscle cell fate determination(GO:0007521)
0.0 0.2 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
0.0 0.4 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.4 GO:0040031 snRNA modification(GO:0040031)
0.0 0.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.9 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0044241 lipid digestion(GO:0044241)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.5 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.5 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.1 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 1.1 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 1.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.3 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.3 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.3 GO:0001842 neural fold formation(GO:0001842)
0.0 0.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 1.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0072610 interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.0 0.2 GO:0015786 UDP-glucose transport(GO:0015786) protein O-linked fucosylation(GO:0036066)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.2 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) icosanoid biosynthetic process(GO:0046456) prostanoid biosynthetic process(GO:0046457) fatty acid derivative biosynthetic process(GO:1901570)
0.0 2.7 GO:1904591 positive regulation of protein import(GO:1904591)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 2.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.0 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0019043 establishment of viral latency(GO:0019043)
0.0 1.8 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.0 0.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.4 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 1.3 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940) contact inhibition(GO:0060242)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0021554 optic nerve development(GO:0021554)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0046596 regulation of viral entry into host cell(GO:0046596) negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1902750 negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.3 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.8 GO:0031016 pancreas development(GO:0031016)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.5 GO:2000191 regulation of fatty acid transport(GO:2000191)
0.0 0.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.4 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.3 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0021539 subthalamus development(GO:0021539)
0.0 0.1 GO:0043489 RNA stabilization(GO:0043489)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 1.7 GO:0007601 visual perception(GO:0007601)
0.0 0.0 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1990173 regulation of establishment of protein localization to chromosome(GO:0070202) regulation of establishment of protein localization to telomere(GO:0070203) protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.8 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:1903671 negative regulation of sprouting angiogenesis(GO:1903671)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006) cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:1904738 vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752) positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.0 0.0 GO:0010726 regulation of hydrogen peroxide metabolic process(GO:0010310) positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 1.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0090169 regulation of spindle assembly(GO:0090169)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0034244 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.8 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0051030 snRNA transport(GO:0051030)
0.0 0.5 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.0 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.2 GO:0043486 histone exchange(GO:0043486)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.0 GO:0036124 histone H3-K9 trimethylation(GO:0036124)
0.0 0.4 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.2 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0045760 positive regulation of action potential(GO:0045760)
0.0 0.0 GO:0086103 G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.4 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.0 GO:2000542 negative regulation of endodermal cell differentiation(GO:1903225) negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0003338 metanephros morphogenesis(GO:0003338)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.2 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.9 GO:0010038 response to metal ion(GO:0010038)
0.0 0.7 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.0 2.9 GO:0033186 CAF-1 complex(GO:0033186)
0.9 6.1 GO:0001740 Barr body(GO:0001740)
0.8 4.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 3.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.5 1.5 GO:0044194 cytolytic granule(GO:0044194)
0.5 1.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.4 2.0 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 2.7 GO:0033503 HULC complex(GO:0033503)
0.4 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.3 2.4 GO:0000322 storage vacuole(GO:0000322)
0.3 5.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 1.7 GO:0071986 Ragulator complex(GO:0071986)
0.3 0.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 3.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 1.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 1.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0035101 FACT complex(GO:0035101)
0.2 1.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 0.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 0.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 1.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 3.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.2 0.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 0.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.5 GO:0044299 C-fiber(GO:0044299)
0.2 0.7 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.2 1.4 GO:0042382 paraspeckles(GO:0042382)
0.2 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.8 GO:0005915 zonula adherens(GO:0005915)
0.2 2.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 1.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 3.4 GO:0030914 STAGA complex(GO:0030914)
0.2 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.2 0.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.0 GO:0097452 GAIT complex(GO:0097452)
0.1 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.9 GO:0045179 apical cortex(GO:0045179)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.1 1.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.3 GO:0061617 MICOS complex(GO:0061617)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.9 GO:0031514 motile cilium(GO:0031514)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0071817 MMXD complex(GO:0071817)
0.1 0.4 GO:1990047 spindle matrix(GO:1990047)
0.1 0.3 GO:0031082 BLOC complex(GO:0031082)
0.1 0.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.6 GO:0032133 interphase microtubule organizing center(GO:0031021) chromosome passenger complex(GO:0032133)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.5 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 2.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.2 GO:0000243 commitment complex(GO:0000243)
0.1 1.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 2.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 2.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 1.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.6 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 5.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 3.2 GO:0016235 aggresome(GO:0016235)
0.1 3.7 GO:0005844 polysome(GO:0005844)
0.1 1.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 1.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0090537 CERF complex(GO:0090537)
0.1 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 3.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0070652 HAUS complex(GO:0070652)
0.1 1.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.8 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 1.2 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0071953 fibrinogen complex(GO:0005577) elastic fiber(GO:0071953)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0044391 ribosomal subunit(GO:0044391)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 6.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 1.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0033202 DNA helicase complex(GO:0033202)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0022624 proteasome accessory complex(GO:0022624)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 5.6 GO:0016604 nuclear body(GO:0016604)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.6 2.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.5 1.6 GO:0004454 ketohexokinase activity(GO:0004454)
0.5 3.1 GO:0043426 MRF binding(GO:0043426)
0.5 1.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.5 3.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 1.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.5 1.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 1.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4 2.7 GO:0016936 galactoside binding(GO:0016936)
0.4 2.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.4 4.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 1.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 1.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 1.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 2.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 1.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.4 2.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 1.4 GO:1990460 leptin receptor binding(GO:1990460)
0.3 1.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3 1.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 2.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.3 2.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821) endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3 3.0 GO:0051434 BH3 domain binding(GO:0051434)
0.3 2.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.3 0.9 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.3 0.9 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.3 0.8 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 1.9 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 1.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 1.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.2 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 10.2 GO:0030332 cyclin binding(GO:0030332)
0.2 1.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 2.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.0 GO:1990405 protein antigen binding(GO:1990405)
0.2 2.4 GO:0031386 protein tag(GO:0031386)
0.2 0.9 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 8.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.8 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 2.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 2.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 4.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1 0.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.2 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.1 2.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 4.5 GO:0045182 translation regulator activity(GO:0045182)
0.1 3.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 4.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 4.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.8 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.3 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.9 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.7 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.2 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0008430 selenium binding(GO:0008430)
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 9.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.7 GO:0005507 copper ion binding(GO:0005507)
0.1 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.5 GO:0070990 snRNP binding(GO:0070990)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 2.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.4 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 2.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.3 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:1990269 GTP-dependent protein kinase activity(GO:0034211) RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 1.0 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.5 GO:0003774 motor activity(GO:0003774)
0.0 0.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.2 5.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.2 4.9 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 5.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.5 PID_ATR_PATHWAY ATR signaling pathway
0.1 3.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 7.4 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 1.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 4.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 5.1 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.1 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 0.5 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 1.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.5 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 2.4 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 3.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.1 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 4.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.3 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.1 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.2 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.2 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.4 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID_ATM_PATHWAY ATM pathway
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.1 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.7 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.1 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 0.4 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 2.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 8.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 5.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.1 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 6.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 1.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 6.2 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.1 3.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 2.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.3 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 13.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 1.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.1 1.7 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 9.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 0.8 REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1 1.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.2 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.5 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.1 2.8 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 0.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 1.9 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 4.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.4 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.6 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 0.5 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.9 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.9 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.4 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.6 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 2.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 3.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.0 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 2.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 8.1 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.0 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import