Motif ID: Hsf4

Z-value: 0.956


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_5802640 2.956 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
Malat1


metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)


chr2_+_121456963 1.791 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr17_+_17316078 1.658 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr12_-_110696289 1.623 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_110696332 1.616 ENSMUST00000094361.4
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr1_+_194938821 1.544 ENSMUST00000016638.2
ENSMUST00000110815.2
Cd34

CD34 antigen

chr7_-_19310035 1.502 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chrX_-_109013389 1.365 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr5_-_123749371 1.333 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749393 1.299 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr13_-_62607499 1.173 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr12_+_75308308 1.165 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr17_+_27029259 1.120 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr13_-_111490111 1.114 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr12_-_110696248 1.095 ENSMUST00000124156.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chrX_+_42149288 1.084 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr7_-_126949499 1.082 ENSMUST00000106339.1
ENSMUST00000052937.5
Asphd1

aspartate beta-hydroxylase domain containing 1

chr11_-_26210553 1.027 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr10_+_100488289 1.002 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr2_-_28466266 0.949 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr11_-_93968242 0.937 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr9_+_13827708 0.933 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr17_+_21707682 0.902 ENSMUST00000073312.6
Zfp760
zinc finger protein 760
chr5_+_30281377 0.894 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr4_+_152178126 0.891 ENSMUST00000075363.3
Acot7
acyl-CoA thioesterase 7
chr6_+_86527312 0.870 ENSMUST00000181928.1
1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr9_-_13827029 0.870 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr5_+_66676098 0.859 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr13_-_111490028 0.850 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr12_-_110695860 0.841 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_172472512 0.840 ENSMUST00000029007.2
Fam209
family with sequence similarity 209
chr4_+_40722461 0.837 ENSMUST00000030118.3
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_-_189688074 0.825 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr6_-_136941887 0.816 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr10_-_86011833 0.801 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr1_+_55088132 0.793 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr9_-_13826946 0.782 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr14_-_79390666 0.779 ENSMUST00000022597.7
Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr15_+_75704280 0.754 ENSMUST00000121137.1
ENSMUST00000023244.5
Rhpn1

rhophilin, Rho GTPase binding protein 1

chr16_-_84835557 0.752 ENSMUST00000138279.1
ENSMUST00000023608.7
Atp5j

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

chr4_-_133545906 0.722 ENSMUST00000030665.6
Nudc
nuclear distribution gene C homolog (Aspergillus)
chr5_-_92675253 0.721 ENSMUST00000151180.1
ENSMUST00000150359.1
Ccdc158

coiled-coil domain containing 158

chr10_+_127759721 0.720 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr19_-_29812952 0.707 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr4_+_127077374 0.702 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr17_+_34135182 0.701 ENSMUST00000042121.9
H2-DMa
histocompatibility 2, class II, locus DMa
chr9_+_118040475 0.699 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr16_+_23107754 0.694 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2

eukaryotic translation initiation factor 4A2

chr1_+_195017399 0.693 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr14_+_34375504 0.686 ENSMUST00000111908.1
Mmrn2
multimerin 2
chr10_-_100589205 0.682 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr17_+_17831004 0.676 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr11_-_93968293 0.666 ENSMUST00000170303.1
Gm20390
predicted gene 20390
chr19_+_25505618 0.654 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr13_+_81657732 0.653 ENSMUST00000049055.6
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr17_+_35424842 0.650 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr16_+_23107413 0.642 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr2_+_157560078 0.638 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chrX_-_73659724 0.638 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr15_+_82252397 0.638 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr11_-_116335384 0.636 ENSMUST00000036215.7
Foxj1
forkhead box J1
chrX_+_42149534 0.632 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr14_-_65833963 0.627 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr11_+_21239279 0.624 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr3_-_113630068 0.607 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr15_-_66801577 0.606 ENSMUST00000168589.1
Sla
src-like adaptor
chr18_-_3337539 0.594 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr10_-_86705485 0.591 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chrX_-_73660047 0.578 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr6_-_136941494 0.570 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr14_+_18271122 0.569 ENSMUST00000132374.1
ENSMUST00000133460.1
Nkiras1

NFKB inhibitor interacting Ras-like protein 1

chr8_-_71537402 0.562 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr2_-_64975762 0.558 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr16_-_84835484 0.553 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr10_+_80826656 0.533 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1



ornithine decarboxylase antizyme 1



chr11_-_48946148 0.532 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr3_+_30792876 0.529 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr14_+_34170640 0.524 ENSMUST00000104925.3
Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chr6_+_48647224 0.521 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr6_-_59024470 0.520 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr6_-_54972603 0.520 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr4_-_107684228 0.518 ENSMUST00000069271.4
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr6_-_128438673 0.517 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr19_-_4625612 0.517 ENSMUST00000025823.3
Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr4_-_151988950 0.513 ENSMUST00000105665.2
ENSMUST00000036680.1
Thap3

THAP domain containing, apoptosis associated protein 3

chr16_+_44943737 0.512 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr16_+_21794320 0.507 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr11_-_116843449 0.497 ENSMUST00000047616.3
Jmjd6
jumonji domain containing 6
chr13_-_23574196 0.490 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chr13_-_51203065 0.481 ENSMUST00000091708.4
Hist1h2al
histone cluster 1, H2al
chr7_-_120982260 0.473 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr1_+_75210832 0.469 ENSMUST00000027401.4
ENSMUST00000144355.1
ENSMUST00000123825.1
Stk16


serine/threonine kinase 16


chr18_-_61259987 0.464 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr1_+_59684949 0.464 ENSMUST00000027174.3
Nop58
NOP58 ribonucleoprotein
chr15_-_82354280 0.463 ENSMUST00000023085.5
Ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)
chr6_+_125049952 0.455 ENSMUST00000088294.5
ENSMUST00000032481.7
Acrbp

proacrosin binding protein

chr19_-_5366626 0.455 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr11_+_116843278 0.455 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr1_+_153874335 0.452 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr9_-_105495130 0.441 ENSMUST00000038118.7
Atp2c1
ATPase, Ca++-sequestering
chr18_+_53176345 0.440 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr1_-_55088024 0.436 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr6_-_136941694 0.435 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr12_-_79172609 0.433 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr19_-_5845471 0.427 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr15_+_87625214 0.427 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr4_-_46566432 0.425 ENSMUST00000030021.7
ENSMUST00000107757.1
Coro2a

coronin, actin binding protein 2A

chr7_+_136894598 0.422 ENSMUST00000081510.2
Mgmt
O-6-methylguanine-DNA methyltransferase
chr4_-_40722307 0.422 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr18_-_70472429 0.421 ENSMUST00000067556.3
4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr13_-_22042949 0.421 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr11_-_52000432 0.415 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr5_-_137962955 0.415 ENSMUST00000077119.6
Gjc3
gap junction protein, gamma 3
chr11_+_4218220 0.415 ENSMUST00000020699.3
Gatsl3
GATS protein-like 3
chr12_-_72236692 0.414 ENSMUST00000021497.9
ENSMUST00000137990.1
Rtn1

reticulon 1

chr17_+_21491256 0.413 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr18_-_10706688 0.410 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr17_+_35379608 0.409 ENSMUST00000081435.4
H2-Q4
histocompatibility 2, Q region locus 4
chr16_+_19760232 0.408 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr18_-_36766198 0.403 ENSMUST00000061522.7
Dnd1
dead end homolog 1 (zebrafish)
chr12_-_54695885 0.401 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chr7_+_92561141 0.392 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b

coiled-coil domain containing 90B

chr2_-_175133322 0.389 ENSMUST00000099029.3
Gm14399
predicted gene 14399
chr11_-_49187159 0.389 ENSMUST00000046522.6
Btnl9
butyrophilin-like 9
chr3_+_79591356 0.378 ENSMUST00000029382.7
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr5_+_43868802 0.378 ENSMUST00000030964.4
Cd38
CD38 antigen
chr7_-_116334132 0.376 ENSMUST00000170953.1
Rps13
ribosomal protein S13
chr17_+_3532554 0.372 ENSMUST00000168560.1
Cldn20
claudin 20
chr5_+_121204477 0.372 ENSMUST00000031617.9
Rpl6
ribosomal protein L6
chr5_-_45450121 0.370 ENSMUST00000127562.1
Qdpr
quinoid dihydropteridine reductase
chr11_+_116657106 0.368 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr11_-_16508149 0.365 ENSMUST00000109642.1
Sec61g
SEC61, gamma subunit
chr2_+_19344820 0.363 ENSMUST00000150514.1
ENSMUST00000136456.1
4930447M23Rik

RIKEN cDNA 4930447M23 gene

chr19_-_60790692 0.361 ENSMUST00000025955.6
Eif3a
eukaryotic translation initiation factor 3, subunit A
chr13_+_22043189 0.361 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chrX_+_73214333 0.361 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
Xlr4b




X-linked lymphocyte-regulated 4B




chr7_+_119895836 0.354 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr9_+_64235201 0.354 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr14_+_3449379 0.350 ENSMUST00000096168.5
Gm10408
predicted gene 10408
chr2_-_118256929 0.350 ENSMUST00000028820.6
ENSMUST00000028821.3
Fsip1

fibrous sheath-interacting protein 1

chr19_+_8740712 0.349 ENSMUST00000163172.1
1700092M07Rik
RIKEN cDNA 1700092M07 gene
chr7_+_4792874 0.345 ENSMUST00000032597.5
ENSMUST00000078432.4
Rpl28

ribosomal protein L28

chr5_+_129020069 0.345 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr16_-_22265950 0.344 ENSMUST00000161286.1
Tra2b
transformer 2 beta homolog (Drosophila)
chr4_-_43653560 0.343 ENSMUST00000107870.2
Spag8
sperm associated antigen 8
chrX_-_61185558 0.341 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr8_-_105933832 0.341 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr6_+_51470339 0.339 ENSMUST00000094623.3
Cbx3
chromobox 3
chr19_+_46328179 0.338 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr11_+_21091291 0.333 ENSMUST00000093290.5
Peli1
pellino 1
chr17_-_34972124 0.332 ENSMUST00000087328.2
ENSMUST00000179128.1
Hspa1a

heat shock protein 1A

chr5_+_29735940 0.328 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr3_-_107943390 0.318 ENSMUST00000106681.1
Gstm6
glutathione S-transferase, mu 6
chr5_-_45450143 0.317 ENSMUST00000154962.1
Qdpr
quinoid dihydropteridine reductase
chr17_+_35470083 0.315 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10

histocompatibility 2, Q region locus 10

chr9_+_118040509 0.311 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chr7_-_28741780 0.306 ENSMUST00000056078.8
Mrps12
mitochondrial ribosomal protein S12
chr19_-_28967794 0.305 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr2_-_24975084 0.304 ENSMUST00000045604.3
Mrpl41
mitochondrial ribosomal protein L41
chr4_-_41048124 0.302 ENSMUST00000030136.6
Aqp7
aquaporin 7
chr7_+_49759100 0.298 ENSMUST00000085272.5
Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr5_-_45450221 0.298 ENSMUST00000015950.5
Qdpr
quinoid dihydropteridine reductase
chr9_+_112227443 0.297 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr19_+_34290653 0.297 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr11_-_101278927 0.297 ENSMUST00000168089.1
ENSMUST00000017332.3
Coa3

cytochrome C oxidase assembly factor 3

chr11_-_117040182 0.292 ENSMUST00000152401.1
ENSMUST00000150628.1
Gm11728

predicted gene 11728

chr2_+_120567652 0.292 ENSMUST00000110711.2
Snap23
synaptosomal-associated protein 23
chr15_+_73724754 0.289 ENSMUST00000163582.1
Ptp4a3
protein tyrosine phosphatase 4a3
chr12_-_72408934 0.289 ENSMUST00000078505.7
Rtn1
reticulon 1
chr2_-_113829069 0.285 ENSMUST00000024005.7
Scg5
secretogranin V
chr5_-_33218229 0.284 ENSMUST00000046186.4
Spon2
spondin 2, extracellular matrix protein
chr7_-_44869788 0.282 ENSMUST00000046575.9
Ptov1
prostate tumor over expressed gene 1
chr12_-_54695813 0.279 ENSMUST00000110713.3
Eapp
E2F-associated phosphoprotein
chr9_+_18292267 0.278 ENSMUST00000001825.7
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr4_+_40722912 0.276 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr13_+_104229366 0.275 ENSMUST00000022227.6
Cenpk
centromere protein K
chr16_+_19760195 0.270 ENSMUST00000121344.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr7_-_89941196 0.270 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr10_-_95416850 0.268 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr3_-_89402650 0.268 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr7_-_28741749 0.267 ENSMUST00000171183.1
Mrps12
mitochondrial ribosomal protein S12
chr15_-_31601786 0.265 ENSMUST00000022842.8
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr10_-_60002993 0.265 ENSMUST00000182116.1
Anapc16
anaphase promoting complex subunit 16
chr7_+_24399606 0.264 ENSMUST00000002280.4
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr15_-_58135047 0.263 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr13_-_24831409 0.262 ENSMUST00000006900.6
Acot13
acyl-CoA thioesterase 13
chr16_-_36784924 0.262 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chrX_+_139217166 0.261 ENSMUST00000166444.1
ENSMUST00000170671.1
ENSMUST00000113041.2
ENSMUST00000113042.2
Mum1l1



melanoma associated antigen (mutated) 1-like 1



chr12_-_116262946 0.258 ENSMUST00000039349.6
Wdr60
WD repeat domain 60
chr17_-_71002488 0.250 ENSMUST00000148960.1
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_+_101279092 0.249 ENSMUST00000103107.4
Cntd1
cyclin N-terminal domain containing 1
chr9_-_44440868 0.248 ENSMUST00000098837.1
Foxr1
forkhead box R1
chr13_+_23574381 0.247 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr1_-_36273425 0.243 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr19_+_26748268 0.240 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr1_+_42953106 0.239 ENSMUST00000179655.1
Gpr45
G protein-coupled receptor 45
chr7_-_46179929 0.237 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr12_+_111758923 0.237 ENSMUST00000118471.1
ENSMUST00000122300.1
Klc1

kinesin light chain 1

chr9_+_50752758 0.237 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr11_-_23497867 0.236 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
Ahsa2


AHA1, activator of heat shock protein ATPase 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.2 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.6 3.0 GO:0035063 nuclear speck organization(GO:0035063)
0.5 1.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 1.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 1.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.7 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 0.9 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 0.9 GO:0007412 axon target recognition(GO:0007412)
0.2 0.6 GO:0019043 establishment of viral latency(GO:0019043)
0.2 0.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.6 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 1.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.7 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 0.6 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.6 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.5 GO:0042228 interleukin-8 biosynthetic process(GO:0042228)
0.1 0.3 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.5 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.1 0.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.2 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 0.5 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793)
0.1 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.5 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.3 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.6 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.4 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.7 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.4 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.9 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.8 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:2000812 response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.2 GO:0043652 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) engulfment of apoptotic cell(GO:0043652)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.8 GO:0021591 ventricular system development(GO:0021591)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0061450 trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 1.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.5 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.3 GO:0046930 pore complex(GO:0046930)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.2 GO:0030911 TPR domain binding(GO:0030911)
0.3 1.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.3 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.5 GO:0043199 sulfate binding(GO:0043199)
0.2 0.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 1.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0042936 dipeptide transporter activity(GO:0042936)
0.1 0.4 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 1.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.3 GO:0005118 sevenless binding(GO:0005118)
0.1 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 2.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.9 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.1 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.1 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.6 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.6 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 2.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins