Motif ID: Zbtb16
Z-value: 1.542

Transcription factors associated with Zbtb16:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zbtb16 | ENSMUSG00000066687.4 | Zbtb16 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zbtb16 | mm10_v2_chr9_-_48835932_48835962 | -0.69 | 1.6e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) |
0.8 | 2.3 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.7 | 2.2 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.7 | 2.1 | GO:0045004 | DNA replication proofreading(GO:0045004) |
0.6 | 1.8 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
0.6 | 1.8 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.5 | 2.2 | GO:0006751 | glutathione catabolic process(GO:0006751) |
0.5 | 2.1 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
0.5 | 2.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.4 | 1.1 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
0.3 | 1.3 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
0.3 | 1.1 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
0.3 | 1.6 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.3 | 1.3 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.3 | 0.8 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.3 | 0.8 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
0.2 | 2.2 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.2 | 1.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.2 | 0.7 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
0.2 | 1.6 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.2 | 1.6 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.2 | 0.6 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.2 | 1.0 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.2 | 1.0 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.2 | 0.7 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
0.2 | 1.1 | GO:0002317 | plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.2 | 0.9 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.2 | 0.5 | GO:0042737 | drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) |
0.2 | 0.9 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.1 | 1.0 | GO:0048318 | axial mesoderm development(GO:0048318) |
0.1 | 1.5 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.1 | 0.8 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.1 | 1.5 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.1 | 8.8 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.1 | 0.8 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.4 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 1.0 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 0.2 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.1 | 0.4 | GO:0048539 | bone marrow development(GO:0048539) |
0.1 | 0.5 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.1 | 1.5 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
0.1 | 0.8 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
0.1 | 0.7 | GO:0033147 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 0.6 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
0.1 | 0.4 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.1 | 0.6 | GO:0043144 | snoRNA processing(GO:0043144) |
0.1 | 0.5 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 0.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.1 | 0.6 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.1 | 0.3 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
0.1 | 1.2 | GO:0006999 | nuclear pore organization(GO:0006999) |
0.1 | 0.7 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
0.1 | 1.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.1 | 1.7 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
0.1 | 3.5 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
0.1 | 0.8 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
0.1 | 0.2 | GO:1903061 | positive regulation of macromitophagy(GO:1901526) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) positive regulation of neuronal action potential(GO:1904457) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
0.1 | 8.9 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.1 | 0.9 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 1.4 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 1.1 | GO:0043536 | positive regulation of blood vessel endothelial cell migration(GO:0043536) |
0.0 | 1.3 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.0 | 0.4 | GO:0030539 | male genitalia development(GO:0030539) |
0.0 | 0.3 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 0.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
0.0 | 1.3 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
0.0 | 0.9 | GO:2001240 | negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
0.0 | 0.6 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 1.4 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 1.1 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 0.7 | GO:0006301 | postreplication repair(GO:0006301) |
0.0 | 0.4 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.4 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.7 | GO:1903146 | regulation of mitophagy(GO:1903146) |
0.0 | 0.2 | GO:0008272 | sulfate transport(GO:0008272) |
0.0 | 0.1 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.0 | 1.4 | GO:0045843 | negative regulation of striated muscle tissue development(GO:0045843) |
0.0 | 0.9 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.1 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 0.8 | GO:0006826 | iron ion transport(GO:0006826) |
0.0 | 0.3 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
0.0 | 0.2 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
0.0 | 1.2 | GO:0007569 | cell aging(GO:0007569) |
0.0 | 0.9 | GO:0043966 | histone H3 acetylation(GO:0043966) |
0.0 | 0.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.8 | GO:0016925 | protein sumoylation(GO:0016925) |
0.0 | 0.2 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
0.0 | 0.0 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
0.0 | 0.6 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway(GO:2001243) |
0.0 | 0.6 | GO:0035082 | cilium movement(GO:0003341) axoneme assembly(GO:0035082) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.5 | 2.1 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.4 | 2.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.4 | 1.6 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.4 | 1.8 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.3 | 1.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.3 | 1.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.3 | 0.8 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.2 | 0.9 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.2 | 1.3 | GO:0030870 | Mre11 complex(GO:0030870) |
0.2 | 0.6 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.2 | 1.0 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.2 | 0.8 | GO:0070552 | BRISC complex(GO:0070552) |
0.2 | 1.0 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.1 | 1.1 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 0.4 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.1 | 0.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.1 | 0.8 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 1.8 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 1.3 | GO:0016460 | myosin II complex(GO:0016460) |
0.1 | 0.7 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
0.1 | 1.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.1 | 0.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.1 | 0.8 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 0.8 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 1.8 | GO:0071010 | prespliceosome(GO:0071010) |
0.1 | 2.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.1 | 2.3 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 1.0 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 0.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 3.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.9 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 1.2 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 2.4 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 1.4 | GO:0035869 | ciliary transition zone(GO:0035869) |
0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.6 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
0.0 | 0.6 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.8 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 2.7 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 2.9 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.0 | 2.1 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.0 | 1.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.5 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 0.6 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.0 | 0.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 0.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 3.1 | GO:0005938 | cell cortex(GO:0005938) |
0.0 | 1.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.7 | 2.1 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
0.6 | 1.8 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
0.5 | 2.4 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
0.4 | 1.6 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.4 | 1.1 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.4 | 1.8 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.3 | 2.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.3 | 1.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.3 | 2.2 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.3 | 0.8 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.2 | 0.7 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.2 | 1.6 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.2 | 1.1 | GO:0043532 | angiostatin binding(GO:0043532) |
0.2 | 0.6 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.2 | 1.7 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.2 | 1.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.2 | 1.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.2 | 8.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.2 | 0.6 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.2 | 1.9 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.2 | 1.1 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.2 | 2.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.2 | 0.5 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.1 | 1.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.1 | 0.6 | GO:0035877 | death effector domain binding(GO:0035877) |
0.1 | 2.3 | GO:0016594 | glycine binding(GO:0016594) |
0.1 | 1.4 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 0.4 | GO:0030519 | snoRNP binding(GO:0030519) |
0.1 | 0.9 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 0.8 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.1 | 1.3 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
0.1 | 0.5 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.1 | 1.5 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.1 | 2.1 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 2.2 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.1 | 0.7 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.1 | 0.9 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.1 | 0.7 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.1 | 1.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.1 | 1.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 0.8 | GO:0015266 | protein channel activity(GO:0015266) |
0.1 | 0.2 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.1 | 2.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.1 | 0.8 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
0.1 | 1.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.1 | 3.1 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.1 | 0.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 0.2 | GO:0001729 | ceramide kinase activity(GO:0001729) |
0.0 | 0.4 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
0.0 | 0.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.0 | 1.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.0 | 0.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.0 | 1.1 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 1.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 1.1 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.4 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 4.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.6 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 1.9 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 1.4 | GO:0008026 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035) |
0.0 | 0.7 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.8 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.6 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 1.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 1.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 1.3 | GO:0035254 | glutamate receptor binding(GO:0035254) |
0.0 | 0.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.9 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.7 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 1.0 | GO:0008565 | protein transporter activity(GO:0008565) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.8 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.1 | 4.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 2.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.1 | 2.1 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 0.6 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.1 | 1.5 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.1 | 8.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.9 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 1.8 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.0 | 1.3 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.4 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 1.0 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 1.1 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.3 | PID_AURORA_A_PATHWAY | Aurora A signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.5 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.2 | 1.8 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 2.1 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
0.1 | 2.7 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.1 | 2.2 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 2.6 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 1.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.1 | 1.1 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.5 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 0.6 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.1 | 0.7 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.1 | 0.3 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.0 | 0.6 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.0 | 0.4 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 0.7 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 1.0 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.8 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 3.6 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 2.2 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
0.0 | 2.2 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 0.3 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 8.5 | REACTOME_HEMOSTASIS | Genes involved in Hemostasis |
0.0 | 0.7 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 1.1 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.4 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.6 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.5 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
0.0 | 0.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.4 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |