Motif ID: Meis2
Z-value: 1.547

Transcription factors associated with Meis2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Meis2 | ENSMUSG00000027210.14 | Meis2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Meis2 | mm10_v2_chr2_-_116065798_116065853 | 0.83 | 2.1e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.6 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
1.3 | 5.2 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
1.3 | 3.8 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
1.0 | 2.9 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
0.8 | 2.4 | GO:0031554 | regulation of DNA-templated transcription, termination(GO:0031554) |
0.7 | 3.7 | GO:1903587 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
0.7 | 4.7 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.6 | 3.5 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.5 | 2.3 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.5 | 1.4 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
0.5 | 1.8 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.4 | 2.2 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
0.4 | 1.1 | GO:1904580 | quinolinate biosynthetic process(GO:0019805) regulation of intracellular mRNA localization(GO:1904580) |
0.4 | 5.5 | GO:0032098 | regulation of appetite(GO:0032098) |
0.4 | 2.2 | GO:1904923 | regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) |
0.4 | 2.8 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
0.3 | 3.1 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.3 | 1.3 | GO:0032095 | regulation of response to food(GO:0032095) |
0.3 | 0.6 | GO:0014735 | regulation of muscle atrophy(GO:0014735) |
0.3 | 2.2 | GO:0015824 | L-alanine transport(GO:0015808) proline transport(GO:0015824) |
0.3 | 1.5 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.3 | 0.3 | GO:0098907 | regulation of SA node cell action potential(GO:0098907) |
0.3 | 2.0 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
0.3 | 0.9 | GO:0061744 | motor behavior(GO:0061744) |
0.3 | 2.4 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
0.3 | 3.9 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
0.3 | 5.9 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
0.3 | 1.0 | GO:1900368 | regulation of RNA interference(GO:1900368) |
0.2 | 2.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.2 | 1.9 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
0.2 | 0.7 | GO:0051105 | regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) |
0.2 | 1.6 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) spindle assembly involved in meiosis(GO:0090306) |
0.2 | 1.5 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.2 | 0.6 | GO:0060126 | hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126) |
0.2 | 0.6 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.2 | 1.8 | GO:2000194 | regulation of female gonad development(GO:2000194) |
0.2 | 0.6 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
0.2 | 1.7 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.2 | 1.3 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
0.2 | 0.9 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.2 | 1.3 | GO:0035745 | T-helper 2 cell cytokine production(GO:0035745) |
0.2 | 0.6 | GO:0070428 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
0.2 | 0.5 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
0.2 | 3.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.2 | 1.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.2 | 1.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.2 | 0.9 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.2 | 0.5 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.2 | 0.8 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
0.2 | 1.3 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.2 | 0.8 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.2 | 1.7 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.2 | 2.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.2 | 2.1 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.1 | 2.7 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 1.0 | GO:0032264 | IMP salvage(GO:0032264) |
0.1 | 0.4 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
0.1 | 1.0 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
0.1 | 1.1 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.1 | 1.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 0.9 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.1 | 1.7 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.1 | 4.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.1 | 1.0 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.1 | 0.9 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.1 | 3.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 0.5 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.1 | 1.0 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 0.6 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
0.1 | 0.9 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.1 | 1.5 | GO:0044144 | regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144) |
0.1 | 0.3 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
0.1 | 0.5 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.1 | 0.3 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
0.1 | 0.8 | GO:0031642 | negative regulation of myelination(GO:0031642) |
0.1 | 0.3 | GO:0006533 | aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416) |
0.1 | 0.8 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.1 | 0.3 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.5 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.1 | 0.2 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.1 | 0.5 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.1 | 2.1 | GO:0051968 | positive regulation of synaptic transmission, glutamatergic(GO:0051968) |
0.1 | 1.1 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 6.6 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.1 | 1.3 | GO:0048070 | platelet formation(GO:0030220) regulation of developmental pigmentation(GO:0048070) |
0.1 | 3.4 | GO:0030042 | actin filament depolymerization(GO:0030042) |
0.1 | 0.4 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.1 | 0.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.1 | 2.2 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.1 | 0.4 | GO:0010878 | cholesterol storage(GO:0010878) very-low-density lipoprotein particle assembly(GO:0034379) |
0.1 | 0.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.1 | 0.5 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
0.1 | 1.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.1 | 0.7 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
0.1 | 0.2 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
0.1 | 1.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.1 | 1.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
0.1 | 0.4 | GO:0098707 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.1 | 1.5 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.1 | 0.3 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.1 | 0.7 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
0.0 | 2.9 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
0.0 | 0.2 | GO:0070627 | ferrous iron import(GO:0070627) |
0.0 | 1.1 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.9 | GO:0030307 | positive regulation of cell growth(GO:0030307) |
0.0 | 0.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
0.0 | 0.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.8 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.0 | 0.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.2 | GO:0002544 | chronic inflammatory response(GO:0002544) |
0.0 | 0.5 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) |
0.0 | 0.6 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
0.0 | 3.7 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.6 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
0.0 | 2.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.8 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.0 | 2.0 | GO:0016575 | histone deacetylation(GO:0016575) |
0.0 | 4.3 | GO:0008643 | carbohydrate transport(GO:0008643) |
0.0 | 1.5 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 1.4 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
0.0 | 0.9 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
0.0 | 1.0 | GO:0035690 | cellular response to drug(GO:0035690) |
0.0 | 0.2 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 0.1 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
0.0 | 1.6 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
0.0 | 0.1 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.0 | 2.6 | GO:0007605 | sensory perception of sound(GO:0007605) |
0.0 | 0.3 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
0.0 | 0.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.5 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 0.2 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.2 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.0 | 0.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 1.6 | GO:0098656 | anion transmembrane transport(GO:0098656) |
0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.2 | GO:0001782 | B cell homeostasis(GO:0001782) |
0.0 | 1.2 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
0.0 | 0.6 | GO:0006998 | nuclear envelope organization(GO:0006998) |
0.0 | 1.7 | GO:1990830 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
0.0 | 0.1 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
0.0 | 1.1 | GO:0034614 | cellular response to reactive oxygen species(GO:0034614) |
0.0 | 0.2 | GO:0030262 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262) |
0.0 | 0.3 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.7 | 3.4 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.5 | 1.5 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
0.5 | 5.9 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.5 | 3.9 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.5 | 1.4 | GO:0016939 | kinesin II complex(GO:0016939) |
0.4 | 1.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.3 | 1.0 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.3 | 5.0 | GO:0005614 | interstitial matrix(GO:0005614) |
0.3 | 1.5 | GO:0097443 | sorting endosome(GO:0097443) |
0.3 | 3.7 | GO:0043203 | axon hillock(GO:0043203) |
0.3 | 2.1 | GO:0005883 | neurofilament(GO:0005883) |
0.3 | 1.0 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.3 | 1.0 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.3 | 0.8 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.2 | 3.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.2 | 2.1 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.2 | 4.7 | GO:0001891 | phagocytic cup(GO:0001891) |
0.2 | 0.9 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.2 | 1.3 | GO:0033263 | CORVET complex(GO:0033263) |
0.2 | 2.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.2 | 1.9 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 1.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.1 | 0.5 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.1 | 0.9 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.1 | 1.7 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.1 | 1.9 | GO:0030008 | TRAPP complex(GO:0030008) |
0.1 | 2.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 3.1 | GO:0031430 | M band(GO:0031430) |
0.1 | 1.5 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.1 | 2.6 | GO:0002102 | podosome(GO:0002102) |
0.1 | 1.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.1 | 0.5 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.1 | 1.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 1.4 | GO:0044292 | dendrite terminus(GO:0044292) |
0.1 | 0.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 9.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.9 | GO:0070545 | PeBoW complex(GO:0070545) |
0.1 | 0.2 | GO:0098888 | extrinsic component of presynaptic membrane(GO:0098888) |
0.1 | 6.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.1 | 1.5 | GO:0042641 | actomyosin(GO:0042641) |
0.1 | 0.8 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 3.2 | GO:0045171 | intercellular bridge(GO:0045171) |
0.1 | 0.6 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 2.0 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 1.7 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 0.4 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 0.8 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
0.0 | 0.2 | GO:0035859 | Seh1-associated complex(GO:0035859) |
0.0 | 0.3 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.6 | GO:0097386 | glial cell projection(GO:0097386) |
0.0 | 0.2 | GO:0098536 | deuterosome(GO:0098536) |
0.0 | 1.1 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 2.4 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.5 | GO:0000242 | pericentriolar material(GO:0000242) |
0.0 | 2.6 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 6.9 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 0.6 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 7.6 | GO:0015629 | actin cytoskeleton(GO:0015629) |
0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 2.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.6 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.2 | GO:0097228 | sperm midpiece(GO:0097225) sperm principal piece(GO:0097228) |
0.0 | 0.8 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.6 | GO:0043198 | dendritic shaft(GO:0043198) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 3.8 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
0.9 | 4.6 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
0.9 | 3.5 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
0.9 | 3.5 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.8 | 2.4 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.7 | 2.2 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.6 | 2.4 | GO:0038025 | reelin receptor activity(GO:0038025) |
0.5 | 2.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
0.5 | 1.4 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
0.5 | 3.2 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.4 | 1.3 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
0.4 | 1.6 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.3 | 2.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.3 | 5.9 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.3 | 0.9 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.3 | 0.9 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.3 | 1.3 | GO:0051425 | PTB domain binding(GO:0051425) |
0.3 | 3.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.2 | 2.9 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.2 | 1.0 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
0.2 | 0.9 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
0.2 | 4.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.2 | 0.6 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.2 | 0.6 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.2 | 1.0 | GO:0070883 | pre-miRNA binding(GO:0070883) |
0.2 | 1.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.2 | 1.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.2 | 4.3 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.2 | 0.6 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.2 | 0.5 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
0.2 | 1.6 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.2 | 1.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.2 | 3.7 | GO:0071949 | FAD binding(GO:0071949) |
0.2 | 0.5 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.2 | 0.7 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.2 | 1.1 | GO:0034452 | dynactin binding(GO:0034452) |
0.2 | 0.8 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.2 | 4.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.2 | 0.6 | GO:0035877 | death effector domain binding(GO:0035877) |
0.2 | 0.9 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 1.0 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 0.4 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.1 | 2.2 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.1 | 1.9 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.4 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
0.1 | 1.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.1 | 1.3 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.1 | 2.0 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 1.0 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.1 | 0.3 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.1 | 2.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 5.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.1 | 0.3 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.1 | 0.4 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.1 | 0.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.1 | 2.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 4.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.1 | 1.8 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 4.5 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 1.0 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 1.5 | GO:0015248 | sterol transporter activity(GO:0015248) |
0.1 | 1.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.4 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
0.1 | 0.5 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.1 | 1.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 0.3 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 0.6 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.1 | 0.4 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 1.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 0.2 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 0.3 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.1 | 0.7 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.1 | 0.3 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.2 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 0.2 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 0.8 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.0 | 4.0 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 2.8 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.7 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 0.7 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
0.0 | 1.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.2 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.0 | 1.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.0 | 0.5 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 1.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 6.2 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.0 | 0.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 1.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 1.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 2.9 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 0.1 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.0 | 0.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.0 | 3.8 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 2.8 | GO:0008201 | heparin binding(GO:0008201) |
0.0 | 0.6 | GO:0043394 | proteoglycan binding(GO:0043394) |
0.0 | 0.6 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 1.7 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.0 | 0.9 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 8.2 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 0.3 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.7 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.4 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.4 | GO:0016859 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859) |
0.0 | 0.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.3 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.1 | 2.2 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 1.8 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.1 | 2.2 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.1 | 2.3 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 1.4 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.6 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.2 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 2.1 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 1.5 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 0.4 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.0 | 0.7 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.6 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 1.4 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 1.5 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 1.3 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.5 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.5 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.5 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.6 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.5 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.6 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
0.0 | 1.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 9.4 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.2 | 6.1 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
0.1 | 1.9 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.1 | 2.4 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
0.1 | 4.6 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.1 | 3.0 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.1 | 4.7 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.1 | 1.0 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.1 | 2.2 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 1.5 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.1 | 1.3 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.1 | 1.0 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.1 | 2.2 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 1.4 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.1 | 0.8 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 2.0 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
0.1 | 0.6 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.0 | 0.5 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 3.7 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.6 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 1.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 1.7 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.5 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.9 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 2.4 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 0.2 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 1.6 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.0 | 0.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 0.6 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
0.0 | 0.1 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 0.3 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 0.9 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.5 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |