Motif ID: Nanog

Z-value: 0.613


Transcription factors associated with Nanog:

Gene SymbolEntrez IDGene Name
Nanog ENSMUSG00000012396.6 Nanog

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogmm10_v2_chr6_+_122707489_1227076080.145.9e-01Click!


Activity profile for motif Nanog.

activity profile for motif Nanog


Sorted Z-values histogram for motif Nanog

Sorted Z-values for motif Nanog



Network of associatons between targets according to the STRING database.



First level regulatory network of Nanog

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66831625 1.442 ENSMUST00000164163.1
Sla
src-like adaptor
chr13_-_41273977 1.293 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chrY_-_1245685 1.240 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr18_-_35215008 1.111 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr2_+_134786154 0.979 ENSMUST00000110116.1
Plcb1
phospholipase C, beta 1
chr17_-_81649607 0.919 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr7_+_49246131 0.861 ENSMUST00000064395.6
Nav2
neuron navigator 2
chr6_+_80018877 0.855 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr17_+_3397189 0.723 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr17_+_46297406 0.714 ENSMUST00000061722.6
ENSMUST00000166280.1
Dlk2

delta-like 2 homolog (Drosophila)

chr18_-_78206408 0.678 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr6_+_80019008 0.673 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chrX_+_153237466 0.661 ENSMUST00000143880.1
Klf8
Kruppel-like factor 8
chr3_+_62419668 0.622 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_-_63212514 0.604 ENSMUST00000032738.5
Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
chr7_+_128688480 0.585 ENSMUST00000118605.1
Inpp5f
inositol polyphosphate-5-phosphatase F
chr1_-_52490736 0.543 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr9_-_15357692 0.531 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr14_-_78536762 0.526 ENSMUST00000123853.1
Akap11
A kinase (PRKA) anchor protein 11
chr1_+_169655493 0.471 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr10_+_39612934 0.461 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr10_-_25200110 0.456 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr16_-_3872378 0.445 ENSMUST00000090522.4
Zfp597
zinc finger protein 597
chr8_+_110721462 0.444 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr13_-_51567084 0.443 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr10_+_58394361 0.443 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr6_+_8259288 0.440 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr14_-_26971232 0.435 ENSMUST00000036570.4
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr7_+_113514085 0.435 ENSMUST00000122890.1
Far1
fatty acyl CoA reductase 1
chr11_+_62248977 0.426 ENSMUST00000018644.2
Adora2b
adenosine A2b receptor
chr12_+_35047180 0.421 ENSMUST00000048519.9
ENSMUST00000163677.1
Snx13

sorting nexin 13

chr2_+_164948219 0.419 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr2_-_45112890 0.416 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr15_+_80097866 0.395 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr10_+_58394381 0.393 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr2_-_144527341 0.392 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr11_-_98053415 0.391 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr12_-_83487708 0.384 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr11_-_109298066 0.379 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr12_-_34528844 0.363 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr6_+_8259327 0.359 ENSMUST00000159378.1
Gm16039
predicted gene 16039
chr15_+_76246747 0.347 ENSMUST00000023225.6
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr5_+_19907774 0.345 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_+_59228743 0.345 ENSMUST00000107537.1
Ube3a
ubiquitin protein ligase E3A
chr19_-_56822161 0.342 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr15_-_71954395 0.339 ENSMUST00000159410.1
Col22a1
collagen, type XXII, alpha 1
chr14_+_65970610 0.338 ENSMUST00000127387.1
Clu
clusterin
chr17_-_32800938 0.334 ENSMUST00000080905.6
Zfp811
zinc finger protein 811
chr15_+_21111452 0.333 ENSMUST00000075132.6
Cdh12
cadherin 12
chr7_+_112742025 0.331 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr5_+_135806859 0.328 ENSMUST00000126232.1
Srrm3
serine/arginine repetitive matrix 3
chr6_-_39725448 0.327 ENSMUST00000002487.8
Braf
Braf transforming gene
chr2_+_62664279 0.323 ENSMUST00000028257.2
Gca
grancalcin
chr13_-_9765137 0.321 ENSMUST00000062658.8
ENSMUST00000130151.1
ENSMUST00000110636.1
ENSMUST00000152725.1
Zmynd11



zinc finger, MYND domain containing 11



chr2_+_69897255 0.317 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr3_-_54915867 0.313 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr14_+_65971049 0.312 ENSMUST00000128539.1
Clu
clusterin
chr19_+_4003334 0.309 ENSMUST00000025806.3
Doc2g
double C2, gamma
chr3_+_88965812 0.307 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr2_-_173276144 0.304 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr11_-_109298090 0.300 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr8_-_34965631 0.300 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_-_52168111 0.295 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chr5_+_25246775 0.293 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr16_+_20696175 0.293 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr11_+_75531690 0.291 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr14_+_65970804 0.288 ENSMUST00000138191.1
Clu
clusterin
chrX_+_159840463 0.288 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr6_+_8259379 0.282 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr12_-_101958148 0.279 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr2_+_116067213 0.278 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr5_+_30711849 0.277 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5

dihydropyrimidinase-like 5

chr17_+_8849974 0.275 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr9_-_15301555 0.270 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr4_+_12906838 0.269 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr11_-_109298121 0.267 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr3_+_10088173 0.266 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr2_-_116067391 0.266 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr6_+_125145235 0.259 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr2_+_29060239 0.258 ENSMUST00000100237.3
Ttf1
transcription termination factor, RNA polymerase I
chr11_+_75468040 0.250 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr10_-_127121125 0.250 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr5_-_147076482 0.238 ENSMUST00000016664.7
Lnx2
ligand of numb-protein X 2
chr11_-_94321957 0.237 ENSMUST00000166312.1
ENSMUST00000107821.2
ENSMUST00000021226.7
ENSMUST00000107820.1
Luc7l3



LUC7-like 3 (S. cerevisiae)



chr7_-_98656530 0.236 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr9_+_109096659 0.236 ENSMUST00000130366.1
Plxnb1
plexin B1
chr3_-_123672321 0.227 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr1_+_135584773 0.224 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr10_+_69785507 0.220 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chr11_+_75532099 0.219 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chrX_-_135009185 0.216 ENSMUST00000113185.2
ENSMUST00000064659.5
Zmat1

zinc finger, matrin type 1

chr13_+_104178797 0.215 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr5_-_124187150 0.213 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_+_109485606 0.210 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr3_-_146499721 0.209 ENSMUST00000029839.4
Spata1
spermatogenesis associated 1
chr7_+_28693032 0.208 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr11_-_20332654 0.205 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_+_153874335 0.205 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr2_+_69897220 0.204 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr7_-_141434402 0.202 ENSMUST00000136354.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr3_+_114030532 0.201 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr5_-_137684665 0.201 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr11_-_20332689 0.201 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_-_29179584 0.200 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr9_+_58554799 0.198 ENSMUST00000098676.2
Gm10657
predicted gene 10657
chrX_+_7822289 0.197 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr17_+_35841668 0.196 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr5_+_19907502 0.191 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_+_89454769 0.190 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr9_-_7184440 0.190 ENSMUST00000140466.1
Dync2h1
dynein cytoplasmic 2 heavy chain 1
chr7_+_25267669 0.187 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr7_+_100706623 0.185 ENSMUST00000107042.1
Fam168a
family with sequence similarity 168, member A
chr7_+_64287665 0.183 ENSMUST00000032736.4
Mtmr10
myotubularin related protein 10
chr10_-_9901079 0.182 ENSMUST00000141722.1
Stxbp5
syntaxin binding protein 5 (tomosyn)
chr10_+_18469958 0.179 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr17_+_7170101 0.178 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr5_-_139484475 0.178 ENSMUST00000110851.1
ENSMUST00000079996.6
Zfand2a

zinc finger, AN1-type domain 2A

chr15_+_98092569 0.178 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chr12_+_24651346 0.177 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr16_+_11405648 0.176 ENSMUST00000096273.2
Snx29
sorting nexin 29
chr2_-_140066661 0.175 ENSMUST00000046656.2
ENSMUST00000099304.3
ENSMUST00000110079.2
Tasp1


taspase, threonine aspartase 1


chr13_-_9764943 0.168 ENSMUST00000110634.1
Zmynd11
zinc finger, MYND domain containing 11
chr11_+_115154139 0.168 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr5_-_124249758 0.168 ENSMUST00000162812.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr15_-_50889043 0.167 ENSMUST00000183997.1
ENSMUST00000183757.1
Trps1

trichorhinophalangeal syndrome I (human)

chr16_+_3872368 0.165 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr1_-_158814469 0.165 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr4_+_136310991 0.162 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr2_-_176149825 0.162 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr10_+_40349265 0.161 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr17_+_21691860 0.160 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr7_-_25754701 0.158 ENSMUST00000108401.1
ENSMUST00000043765.7
Hnrnpul1

heterogeneous nuclear ribonucleoprotein U-like 1

chr11_+_69088490 0.157 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr16_+_19760902 0.155 ENSMUST00000119468.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr14_-_26534870 0.154 ENSMUST00000139075.1
ENSMUST00000102956.1
Slmap

sarcolemma associated protein

chr18_-_67245818 0.154 ENSMUST00000073054.3
Mppe1
metallophosphoesterase 1
chr1_-_152625212 0.149 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr18_-_15718046 0.149 ENSMUST00000053017.6
Chst9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr19_-_32196393 0.145 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr2_-_181581996 0.145 ENSMUST00000057816.8
Uckl1
uridine-cytidine kinase 1-like 1
chr3_-_49757257 0.144 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr9_-_44305595 0.143 ENSMUST00000034629.4
Hinfp
histone H4 transcription factor
chr10_-_109010955 0.143 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr11_+_86484647 0.142 ENSMUST00000020827.6
Rnft1
ring finger protein, transmembrane 1
chr3_-_152193803 0.142 ENSMUST00000050073.6
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr15_-_93519499 0.141 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr15_-_13173607 0.139 ENSMUST00000036439.4
Cdh6
cadherin 6
chr7_-_6730412 0.139 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr15_+_78428564 0.136 ENSMUST00000166142.2
ENSMUST00000162517.1
ENSMUST00000089414.4
Kctd17


potassium channel tetramerisation domain containing 17


chr13_+_24943144 0.136 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr3_+_68869563 0.134 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr1_-_153900198 0.133 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr12_-_72408934 0.133 ENSMUST00000078505.7
Rtn1
reticulon 1
chr16_+_13671858 0.132 ENSMUST00000023365.6
Bfar
bifunctional apoptosis regulator
chr5_+_121397936 0.132 ENSMUST00000042163.8
Naa25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr3_+_79884576 0.131 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr16_-_32877723 0.130 ENSMUST00000119810.1
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr16_+_32877775 0.128 ENSMUST00000023489.4
ENSMUST00000171325.1
Fyttd1

forty-two-three domain containing 1

chr12_-_20900867 0.128 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr19_-_36736653 0.127 ENSMUST00000087321.2
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr10_+_90576570 0.126 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr4_+_126024506 0.126 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chr4_-_126968124 0.119 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chr3_+_79884496 0.118 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr2_-_167062981 0.118 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr16_+_87454976 0.116 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16

ubiquitin specific peptidase 16

chr3_-_69127098 0.116 ENSMUST00000029353.2
Kpna4
karyopherin (importin) alpha 4
chrX_+_8271133 0.113 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr16_-_18622403 0.113 ENSMUST00000167388.1
Gp1bb
glycoprotein Ib, beta polypeptide
chr8_-_83594440 0.112 ENSMUST00000019382.9
ENSMUST00000165740.1
Tecr

trans-2,3-enoyl-CoA reductase

chr5_-_115652974 0.111 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr2_-_37703845 0.110 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr13_-_92131494 0.108 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr14_+_56887795 0.108 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr2_+_144527718 0.106 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr1_+_50927511 0.104 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr10_-_81364846 0.098 ENSMUST00000131736.1
4930404N11Rik
RIKEN cDNA 4930404N11 gene
chr17_+_20945311 0.098 ENSMUST00000007708.7
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr1_+_174501796 0.095 ENSMUST00000030039.7
Fmn2
formin 2
chr4_-_43046196 0.094 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr13_-_12258093 0.093 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr12_+_109549157 0.093 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr13_+_4233730 0.092 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chr4_-_149454971 0.091 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr10_+_38965515 0.089 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr7_+_128246812 0.088 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr4_+_154964117 0.088 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr4_+_109343029 0.088 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr16_-_23520579 0.087 ENSMUST00000089883.5
Masp1
mannan-binding lectin serine peptidase 1
chr17_-_25919506 0.086 ENSMUST00000164982.1
ENSMUST00000179998.1
ENSMUST00000167626.1
ENSMUST00000164738.1
ENSMUST00000026826.7
ENSMUST00000167018.1
Rab40c





Rab40c, member RAS oncogene family





chr4_+_101507947 0.085 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr6_+_38551334 0.082 ENSMUST00000163047.1
ENSMUST00000161538.1
ENSMUST00000057692.4
Luc7l2


LUC7-like 2 (S. cerevisiae)


chr17_-_57247632 0.081 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr14_+_61607455 0.080 ENSMUST00000051184.8
Kcnrg
potassium channel regulator
chr18_+_57142782 0.080 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr2_+_32363680 0.078 ENSMUST00000113331.1
ENSMUST00000113338.2
Ciz1

CDKN1A interacting zinc finger protein 1

chr7_+_103550368 0.078 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr4_+_136310936 0.077 ENSMUST00000131671.1
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr16_+_13671980 0.076 ENSMUST00000069281.7
Bfar
bifunctional apoptosis regulator
chr7_-_6011010 0.076 ENSMUST00000086338.1
Vmn1r65
vomeronasal 1 receptor 65

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.2 0.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.9 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 0.6 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.2 0.9 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.2 0.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 0.9 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 1.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.1 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.1 0.4 GO:0015825 L-serine transport(GO:0015825)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.0 0.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.3 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.1 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0045113 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.5 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.4 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.6 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 1.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.8 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.1 0.9 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects