Motif ID: Atf6

Z-value: 1.231


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_170867784-0.184.8e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_-_1245685 3.847 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr16_-_23988852 3.439 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr3_+_123267445 3.213 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr12_+_82616885 2.666 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr5_+_134986191 2.484 ENSMUST00000094245.2
Cldn3
claudin 3
chr5_-_89883321 2.215 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chrX_+_41401128 2.168 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chrY_-_1245753 2.119 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr6_-_126740151 1.945 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr8_+_125995102 1.869 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr5_+_35056813 1.787 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
Dok7


docking protein 7


chr6_-_101377897 1.774 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr5_-_136170634 1.670 ENSMUST00000041048.1
Orai2
ORAI calcium release-activated calcium modulator 2
chr10_+_29211637 1.594 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr17_+_46297917 1.562 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr8_-_70487314 1.549 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr6_-_8778439 1.508 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1


chr6_-_8778106 1.448 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr6_+_77242644 1.434 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 1.412 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_-_136173492 1.364 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chrX_+_163908982 1.325 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_155276297 1.315 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr16_+_41532999 1.225 ENSMUST00000099761.3
Lsamp
limbic system-associated membrane protein
chr10_-_18743691 1.198 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr13_-_105054895 1.181 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr5_+_35057059 1.153 ENSMUST00000050709.3
Dok7
docking protein 7
chr5_-_65492984 1.112 ENSMUST00000139122.1
Smim14
small integral membrane protein 14
chr11_-_108343917 1.100 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr18_-_31447383 1.088 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr7_+_126950687 1.068 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr4_+_128058962 1.036 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr12_-_4841583 1.027 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr2_+_55437100 1.024 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr7_+_126950518 1.013 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr7_+_126950837 1.008 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr15_-_77956658 1.008 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr13_-_59557230 1.006 ENSMUST00000165370.1
ENSMUST00000109830.2
ENSMUST00000022040.6
ENSMUST00000171606.1
ENSMUST00000167096.1
ENSMUST00000166585.1
Agtpbp1





ATP/GTP binding protein 1





chr4_+_155734800 0.991 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr1_-_136260873 0.980 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr5_+_137288273 0.969 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr4_-_149774238 0.965 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr3_+_101377074 0.942 ENSMUST00000043983.5
Igsf3
immunoglobulin superfamily, member 3
chr13_+_13784278 0.909 ENSMUST00000021734.7
Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr13_+_93303757 0.909 ENSMUST00000109494.1
Homer1
homer homolog 1 (Drosophila)
chr5_+_37185897 0.907 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr14_-_124677089 0.899 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr4_+_88094599 0.887 ENSMUST00000097992.3
Focad
focadhesin
chr2_+_67748212 0.870 ENSMUST00000180887.1
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr16_-_57231434 0.867 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chr16_+_17759601 0.837 ENSMUST00000129199.1
ENSMUST00000165790.1
Klhl22

kelch-like 22

chrX_+_73787002 0.832 ENSMUST00000166518.1
Ssr4
signal sequence receptor, delta
chr6_-_124464772 0.831 ENSMUST00000008297.4
Clstn3
calsyntenin 3
chr15_-_98881255 0.829 ENSMUST00000024518.9
Rhebl1
Ras homolog enriched in brain like 1
chrX_+_73787062 0.818 ENSMUST00000002090.2
Ssr4
signal sequence receptor, delta
chr9_+_72925622 0.818 ENSMUST00000038489.5
Pygo1
pygopus 1
chr18_+_23803962 0.808 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr19_+_4099998 0.771 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr3_-_144205165 0.770 ENSMUST00000120539.1
Lmo4
LIM domain only 4
chr11_+_69991061 0.757 ENSMUST00000018711.8
Gabarap
gamma-aminobutyric acid receptor associated protein
chr13_+_93304066 0.755 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr7_+_132931142 0.755 ENSMUST00000106157.1
Zranb1
zinc finger, RAN-binding domain containing 1
chrX_-_85776606 0.751 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
Gyk


glycerol kinase


chr15_-_81960851 0.744 ENSMUST00000071462.6
ENSMUST00000023112.5
Pmm1

phosphomannomutase 1

chr11_-_96916448 0.744 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr6_-_118479237 0.742 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr11_-_30025915 0.741 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr16_-_4880284 0.733 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr7_+_45785331 0.719 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr4_+_46489248 0.715 ENSMUST00000030018.4
Nans
N-acetylneuraminic acid synthase (sialic acid synthase)
chr15_+_77084367 0.705 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr17_-_24205514 0.695 ENSMUST00000097376.3
ENSMUST00000168410.2
ENSMUST00000167791.2
ENSMUST00000040474.7
Tbc1d24



TBC1 domain family, member 24



chr9_-_98563580 0.691 ENSMUST00000058992.2
4930579K19Rik
RIKEN cDNA 4930579K19 gene
chr8_-_70439557 0.682 ENSMUST00000076615.5
Crtc1
CREB regulated transcription coactivator 1
chr4_+_43406435 0.682 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr12_-_72070991 0.679 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr5_-_118244861 0.674 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr13_-_93499803 0.666 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr1_+_50927511 0.658 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_-_95750335 0.656 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr16_+_17759630 0.630 ENSMUST00000140306.1
ENSMUST00000117192.1
Klhl22

kelch-like 22

chr10_+_111164794 0.627 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr3_+_30792876 0.625 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr16_-_94370450 0.624 ENSMUST00000138514.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr18_+_62977826 0.620 ENSMUST00000025474.6
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr10_-_95416850 0.617 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr16_+_20733104 0.611 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr5_-_135934590 0.607 ENSMUST00000055808.5
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr13_-_111490111 0.598 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr4_+_59003121 0.596 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr13_-_111490028 0.595 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr13_+_5861489 0.594 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr16_-_94370647 0.593 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_17693965 0.592 ENSMUST00000115419.1
St7
suppression of tumorigenicity 7
chr5_-_8367982 0.588 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr5_-_52471534 0.587 ENSMUST00000059428.5
Ccdc149
coiled-coil domain containing 149
chr16_+_94370618 0.585 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chrX_+_134717943 0.582 ENSMUST00000113201.1
ENSMUST00000051256.3
ENSMUST00000113199.1
ENSMUST00000035748.7
ENSMUST00000113198.1
ENSMUST00000113197.1
Armcx1





armadillo repeat containing, X-linked 1





chr11_-_96916366 0.582 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr7_+_133776857 0.573 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
Fank1


fibronectin type 3 and ankyrin repeat domains 1


chr11_+_54438188 0.572 ENSMUST00000046835.7
Fnip1
folliculin interacting protein 1
chr13_+_118714678 0.572 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr5_+_137030275 0.571 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr17_+_45563928 0.568 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chr11_-_69920581 0.567 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr17_+_87107621 0.561 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr3_-_127225847 0.556 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr9_-_51008936 0.553 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr7_-_126082406 0.544 ENSMUST00000073935.5
Gsg1l
GSG1-like
chr6_+_17693905 0.540 ENSMUST00000115420.1
St7
suppression of tumorigenicity 7
chr1_-_66817536 0.530 ENSMUST00000068168.3
ENSMUST00000113987.1
Kansl1l

KAT8 regulatory NSL complex subunit 1-like

chr2_+_156721069 0.527 ENSMUST00000000094.7
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr6_+_17694005 0.524 ENSMUST00000081635.6
ENSMUST00000052113.5
St7

suppression of tumorigenicity 7

chr9_-_103761820 0.521 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr3_+_138065052 0.517 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chrX_-_7375830 0.516 ENSMUST00000115744.1
Usp27x
ubiquitin specific peptidase 27, X chromosome
chrX_+_56346390 0.508 ENSMUST00000101560.3
Zfp449
zinc finger protein 449
chr10_-_95417099 0.497 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr3_+_103575275 0.496 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr7_-_105633525 0.494 ENSMUST00000153371.1
ENSMUST00000106789.1
ENSMUST00000057525.7
Trim3


tripartite motif-containing 3


chr5_-_24447587 0.494 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr12_+_51377560 0.494 ENSMUST00000021335.5
Scfd1
Sec1 family domain containing 1
chr15_+_40655020 0.494 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr2_+_156721037 0.488 ENSMUST00000109566.2
ENSMUST00000146412.2
ENSMUST00000177013.1
ENSMUST00000171030.2
Dlgap4



discs, large homolog-associated protein 4 (Drosophila)



chr4_-_121017201 0.485 ENSMUST00000043200.7
Smap2
small ArfGAP 2
chr17_-_36042690 0.477 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
H2-T22


histocompatibility 2, T region locus 22


chrX_-_136741155 0.475 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr7_-_45466894 0.475 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr11_-_68853119 0.473 ENSMUST00000018880.7
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr9_+_123150941 0.473 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr17_-_37023349 0.472 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr5_-_137533170 0.467 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr13_+_58807884 0.465 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr17_+_45433823 0.462 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr2_-_73386396 0.462 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr11_+_16257706 0.461 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr1_+_143640664 0.457 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_-_105633479 0.457 ENSMUST00000147044.1
ENSMUST00000106791.1
Trim3

tripartite motif-containing 3

chr13_+_46669517 0.452 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr18_+_62977854 0.451 ENSMUST00000150267.1
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr6_+_3498382 0.450 ENSMUST00000001412.10
ENSMUST00000170873.3
ENSMUST00000184752.1
ENSMUST00000164052.3
Ccdc132



coiled-coil domain containing 132



chr11_-_96916407 0.448 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_+_16098458 0.446 ENSMUST00000006181.6
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr6_+_17694167 0.442 ENSMUST00000115418.1
St7
suppression of tumorigenicity 7
chrX_-_73786888 0.441 ENSMUST00000052761.8
Idh3g
isocitrate dehydrogenase 3 (NAD+), gamma
chr16_-_94370695 0.436 ENSMUST00000113906.2
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr14_-_54913089 0.430 ENSMUST00000050772.7
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr7_+_81523555 0.429 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr17_+_37050631 0.425 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr4_+_48585135 0.416 ENSMUST00000030032.6
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr5_-_137533212 0.412 ENSMUST00000111038.1
ENSMUST00000143495.1
Epo
Gnb2
erythropoietin
guanine nucleotide binding protein (G protein), beta 2
chr4_+_127077374 0.405 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr15_-_102510681 0.402 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr19_+_11965817 0.401 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr7_-_67372846 0.400 ENSMUST00000156690.1
ENSMUST00000107476.1
ENSMUST00000076325.5
ENSMUST00000032776.8
ENSMUST00000133074.1
Mef2a




myocyte enhancer factor 2A




chr3_+_103575231 0.390 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr16_-_16829276 0.388 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr3_-_127225917 0.382 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr2_-_91070283 0.380 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr14_+_26638074 0.379 ENSMUST00000022429.2
Arf4
ADP-ribosylation factor 4
chr2_-_91070180 0.379 ENSMUST00000153367.1
ENSMUST00000079976.3
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr17_-_80290476 0.375 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr8_-_11550689 0.364 ENSMUST00000049461.5
Cars2
cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
chr13_-_92131494 0.363 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chrX_-_20291776 0.360 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr10_+_78780470 0.356 ENSMUST00000005490.8
Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr5_-_135078224 0.355 ENSMUST00000067935.4
ENSMUST00000076203.2
Vps37d

vacuolar protein sorting 37D (yeast)

chr19_+_8741669 0.350 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
Stx5a


syntaxin 5A


chr8_+_35587780 0.348 ENSMUST00000037666.5
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr8_-_105255100 0.347 ENSMUST00000093217.2
ENSMUST00000161745.2
ENSMUST00000136822.2
B3gnt9


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9


chr8_+_12984246 0.347 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr11_+_70023905 0.347 ENSMUST00000124568.2
Dlg4
discs, large homolog 4 (Drosophila)
chrX_+_23693043 0.346 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chrX_-_134751331 0.345 ENSMUST00000113194.1
ENSMUST00000052431.5
Armcx6

armadillo repeat containing, X-linked 6

chr8_+_25720054 0.344 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr9_-_78109020 0.343 ENSMUST00000001402.7
Fbxo9
f-box protein 9
chr8_+_4493443 0.341 ENSMUST00000175781.2
Cers4
ceramide synthase 4
chr7_-_100863373 0.340 ENSMUST00000142885.1
ENSMUST00000008462.3
Relt

RELT tumor necrosis factor receptor

chrX_+_166344692 0.336 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr11_-_74590065 0.334 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr6_+_48537560 0.329 ENSMUST00000040361.5
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr16_-_11134624 0.329 ENSMUST00000038424.7
Txndc11
thioredoxin domain containing 11
chr2_+_156721009 0.327 ENSMUST00000131157.2
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr1_+_99772765 0.326 ENSMUST00000086738.3
Cntnap5b
contactin associated protein-like 5B
chr7_+_47050628 0.326 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr15_+_82274935 0.325 ENSMUST00000023095.6
Sept3
septin 3
chr17_-_67354459 0.320 ENSMUST00000037974.8
Ptprm
protein tyrosine phosphatase, receptor type, M
chr9_-_86695897 0.317 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr17_+_83350925 0.314 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
Eml4


echinoderm microtubule associated protein like 4


chr8_+_105701624 0.311 ENSMUST00000093195.6
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr1_+_115684727 0.311 ENSMUST00000043725.7
Cntnap5a
contactin associated protein-like 5A
chrX_+_136741821 0.310 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr19_+_8741413 0.309 ENSMUST00000176381.1
Stx5a
syntaxin 5A
chr6_+_71493850 0.305 ENSMUST00000064637.4
ENSMUST00000114178.1
Rnf103

ring finger protein 103

chr17_-_63863791 0.302 ENSMUST00000050753.3
A930002H24Rik
RIKEN cDNA A930002H24 gene
chr2_-_126876117 0.300 ENSMUST00000028843.5
Trpm7
transient receptor potential cation channel, subfamily M, member 7
chrX_+_57053549 0.300 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr4_-_70534904 0.300 ENSMUST00000107359.2
Megf9
multiple EGF-like-domains 9
chr2_-_126876209 0.296 ENSMUST00000103224.3
Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr3_+_79591356 0.287 ENSMUST00000029382.7
Ppid
peptidylprolyl isomerase D (cyclophilin D)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.7 5.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 2.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 1.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.3 1.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.3 1.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 2.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 1.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.3 3.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 0.8 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.3 1.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 1.0 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 0.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.2 0.6 GO:0070375 ERK5 cascade(GO:0070375)
0.2 0.9 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2 3.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 2.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.5 GO:0003195 tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.7 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.2 0.5 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.6 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 1.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 1.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.0 GO:0060315 response to redox state(GO:0051775) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 1.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 3.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 1.1 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 3.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 3.0 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 0.3 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.4 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.4 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 1.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.7 GO:0090166 Golgi disassembly(GO:0090166)
0.1 1.0 GO:0045176 apical protein localization(GO:0045176)
0.1 0.5 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.6 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.4 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 3.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:0015747 urate transport(GO:0015747)
0.1 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.4 GO:0060416 response to growth hormone(GO:0060416)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.2 GO:0051495 positive regulation of cytoskeleton organization(GO:0051495)
0.1 0.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.6 GO:0043084 penile erection(GO:0043084)
0.1 0.2 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.1 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.8 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 2.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 2.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.4 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.0 0.7 GO:0060746 parental behavior(GO:0060746)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0009405 pathogenesis(GO:0009405)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.4 GO:0007614 short-term memory(GO:0007614)
0.0 0.3 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.3 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of translation in response to stress(GO:0032055) cellular response to cold(GO:0070417)
0.0 0.1 GO:0009268 response to pH(GO:0009268)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0021886 female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.7 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.6 GO:0001707 mesoderm formation(GO:0001707)
0.0 0.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 5.4 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.0 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 4.5 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 3.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.5 GO:0005827 polar microtubule(GO:0005827)
0.1 2.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 2.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 2.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 3.4 GO:0043034 costamere(GO:0043034)
0.1 1.1 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 4.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 3.2 GO:0005657 replication fork(GO:0005657)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 4.4 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 1.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.4 1.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 1.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 1.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.3 2.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 3.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 1.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 1.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 1.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.3 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 3.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.0 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 3.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0071074 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.0 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 1.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.7 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.3 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.2 PID_NECTIN_PATHWAY Nectin adhesion pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 0.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.5 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 3.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.1 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.7 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 2.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.1 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 2.3 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.8 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway