Motif ID: Mnx1_Lhx6_Lmx1a

Z-value: 1.099

Transcription factors associated with Mnx1_Lhx6_Lmx1a:

Gene SymbolEntrez IDGene Name
Lhx6 ENSMUSG00000026890.13 Lhx6
Lmx1a ENSMUSG00000026686.8 Lmx1a
Mnx1 ENSMUSG00000001566.8 Mnx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lmx1amm10_v2_chr1_+_167689108_1676892390.672.2e-03Click!
Lhx6mm10_v2_chr2_-_36105271_36105434-0.617.5e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Mnx1_Lhx6_Lmx1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_61902669 8.246 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr5_+_139543889 7.988 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_+_20737306 7.696 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr6_-_147264124 6.215 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr14_-_48665098 5.508 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr3_+_125404292 4.038 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_55782500 4.016 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr19_+_44493472 3.959 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr14_-_118052235 3.912 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr3_+_125404072 3.866 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_-_102906046 3.587 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_102905740 3.532 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr9_+_119063429 3.239 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr7_-_49636847 3.040 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr2_-_168767136 2.976 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr1_-_172027269 2.948 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr3_-_88410295 2.811 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr13_-_53473074 2.483 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr2_-_168767029 2.448 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr4_-_97778042 2.438 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_+_25372315 2.421 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr5_+_92809372 2.385 ENSMUST00000113054.2
Shroom3
shroom family member 3
chrM_+_2743 2.323 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr14_-_48662740 2.190 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr17_-_48432723 2.175 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr1_-_72284248 2.169 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chrX_-_60893430 2.154 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_-_35845204 2.088 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr10_+_4611971 2.088 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr1_-_172027251 1.939 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr3_+_159839729 1.922 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chrM_+_9452 1.838 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr17_+_17402672 1.791 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr17_+_34592248 1.732 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr19_+_59458372 1.723 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr17_-_70853482 1.703 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr1_+_109983737 1.700 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr19_-_15924560 1.684 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr7_-_5014645 1.672 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr19_-_15924928 1.657 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chrX_+_169685191 1.635 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr11_-_3931789 1.603 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chrX_+_56779437 1.597 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr9_+_65890237 1.536 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chrM_+_7005 1.491 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr19_+_24875679 1.459 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr8_+_45658731 1.451 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr4_-_58499398 1.435 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr8_+_45658666 1.434 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr11_-_3931960 1.393 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr3_+_94372794 1.391 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr10_+_37139558 1.347 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr1_+_12718496 1.335 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_+_59306920 1.333 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr3_-_79841729 1.320 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr7_-_116198487 1.286 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr8_-_84662841 1.276 ENSMUST00000060427.4
Ier2
immediate early response 2
chr10_-_37138863 1.243 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr3_+_24333046 1.176 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr2_-_28916412 1.169 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr5_+_92683625 1.165 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr3_-_157925056 1.165 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr7_-_37773555 1.154 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr9_+_118478344 1.150 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr6_+_138140298 1.132 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr15_-_50889691 1.130 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr2_-_30093642 1.104 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr17_+_36958623 1.100 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr11_+_60537978 1.082 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr7_-_101837776 1.045 ENSMUST00000165052.1
Inppl1
inositol polyphosphate phosphatase-like 1
chr3_+_121291725 1.042 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr1_+_110099295 1.020 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr6_+_7555053 1.006 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr2_-_30093607 0.990 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr10_+_88091070 0.985 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr10_-_6980376 0.978 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr10_+_128337761 0.973 ENSMUST00000005826.7
Cs
citrate synthase
chr2_-_129699833 0.971 ENSMUST00000028883.5
Pdyn
prodynorphin
chr10_+_102158858 0.966 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr9_-_64022043 0.944 ENSMUST00000041029.5
Smad6
SMAD family member 6
chr6_+_138140521 0.934 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr2_-_28916668 0.930 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr3_-_88577208 0.924 ENSMUST00000098952.2
Gm10704
predicted pseudogene 10704
chr17_+_36958571 0.918 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr12_+_55598917 0.917 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr9_+_118478182 0.907 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr7_-_45830776 0.906 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr6_+_125552948 0.905 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr3_+_122044428 0.902 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_-_136875794 0.897 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr15_-_103215285 0.895 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr5_+_9100681 0.886 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr12_-_54986328 0.882 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chrX_-_74246534 0.876 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr12_-_54986363 0.861 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr15_-_9140374 0.853 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr12_-_73047179 0.851 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr1_+_153665666 0.832 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr5_+_138187485 0.831 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr15_+_25773985 0.830 ENSMUST00000125667.1
Myo10
myosin X
chr13_+_23575753 0.827 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr3_+_133338936 0.814 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr18_+_34758890 0.812 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr1_-_183147461 0.806 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr1_+_10993452 0.799 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr10_+_26772477 0.792 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr1_-_180330550 0.774 ENSMUST00000050581.3
Gm5069
predicted pseudogene 5069
chr16_-_56712825 0.772 ENSMUST00000136394.1
Tfg
Trk-fused gene
chr4_-_110292719 0.771 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_+_181767040 0.757 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr13_-_114458720 0.738 ENSMUST00000022287.5
Fst
follistatin
chr9_+_62858085 0.735 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chrX_-_102157065 0.734 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr9_+_72806874 0.730 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chrM_-_14060 0.728 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr3_+_40800778 0.728 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr3_-_116253467 0.724 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr19_+_55895508 0.724 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chrX_+_134308084 0.722 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr1_+_153665627 0.721 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr12_+_3954943 0.718 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr9_+_96258697 0.715 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr2_+_181767283 0.714 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr3_-_141982224 0.711 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr2_-_174346712 0.709 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr16_+_33684538 0.698 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr3_+_54361103 0.698 ENSMUST00000107985.3
ENSMUST00000117373.1
ENSMUST00000073012.6
ENSMUST00000081564.6
Postn



periostin, osteoblast specific factor



chr5_-_138170992 0.675 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_18048784 0.672 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr1_-_75046639 0.671 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr2_+_152754156 0.668 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr13_-_78196373 0.667 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr3_-_87174657 0.665 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr10_-_8886033 0.662 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr1_+_153665587 0.659 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr2_+_109917639 0.634 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chrM_+_11734 0.633 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr14_+_79515618 0.632 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr7_+_125829653 0.627 ENSMUST00000124223.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr4_-_14621669 0.624 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr3_-_33082004 0.623 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr3_+_134236483 0.622 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr2_+_61804453 0.613 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr5_+_15516489 0.612 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr4_+_140701466 0.594 ENSMUST00000038893.5
ENSMUST00000138808.1
Rcc2

regulator of chromosome condensation 2

chr9_-_71163224 0.593 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr17_-_24073479 0.590 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr7_-_116031047 0.588 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr5_+_135994796 0.575 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
Dtx2




deltex 2 homolog (Drosophila)




chr9_+_89199319 0.575 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr10_-_35711891 0.574 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr2_+_3114220 0.567 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr7_+_28881656 0.565 ENSMUST00000066880.4
Capn12
calpain 12
chr1_+_82233112 0.565 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr7_-_38019505 0.556 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr5_-_134946917 0.540 ENSMUST00000051401.2
Cldn4
claudin 4
chr7_-_37772868 0.539 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr4_-_110287479 0.524 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr11_+_101582236 0.523 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
Tmem106a



transmembrane protein 106A



chr11_+_98798653 0.514 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr5_-_77115145 0.500 ENSMUST00000081964.5
Hopx
HOP homeobox
chr6_+_71909046 0.492 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr1_+_180330470 0.481 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr3_-_49757257 0.480 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr2_-_155074447 0.480 ENSMUST00000137242.1
ENSMUST00000054607.9
Ahcy

S-adenosylhomocysteine hydrolase

chr1_-_156034800 0.467 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr9_-_20959785 0.466 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr10_+_88146992 0.464 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr11_-_31671863 0.456 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr2_+_106693185 0.454 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr4_-_155056784 0.449 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chrX_+_152001845 0.446 ENSMUST00000026289.3
ENSMUST00000112617.3
Hsd17b10

hydroxysteroid (17-beta) dehydrogenase 10

chrX_-_134111852 0.443 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr7_-_45103747 0.443 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr2_-_33718789 0.427 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr1_-_93445642 0.422 ENSMUST00000042498.7
Hdlbp
high density lipoprotein (HDL) binding protein
chr13_+_89540636 0.420 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr6_+_34746368 0.414 ENSMUST00000142716.1
Cald1
caldesmon 1
chr7_-_37769624 0.410 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr1_-_156034826 0.404 ENSMUST00000141878.1
ENSMUST00000123705.1
Tor1aip1

torsin A interacting protein 1

chr1_+_156035392 0.367 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr6_+_146642547 0.350 ENSMUST00000032429.2
ENSMUST00000111650.1
Med21

mediator complex subunit 21

chr18_-_15063560 0.349 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr7_+_25681158 0.345 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr12_-_111813834 0.345 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr12_+_111814170 0.342 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr15_-_13173607 0.336 ENSMUST00000036439.4
Cdh6
cadherin 6
chr6_+_29859374 0.333 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr7_-_19399859 0.332 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr3_+_106113229 0.324 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr2_-_132247747 0.316 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr18_-_56975333 0.313 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr11_-_31671727 0.311 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr19_-_11604828 0.309 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr17_+_12119274 0.309 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr18_+_4993795 0.305 ENSMUST00000153016.1
Svil
supervillin
chr5_-_137531952 0.287 ENSMUST00000140139.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr9_+_21955747 0.273 ENSMUST00000053583.5
Swsap1
SWIM type zinc finger 7 associated protein 1
chr5_+_136919137 0.273 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr6_-_90716489 0.272 ENSMUST00000101153.3
Iqsec1
IQ motif and Sec7 domain 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.6 4.9 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.1 8.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.0 6.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
1.0 3.9 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.8 2.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.7 3.0 GO:0015889 cobalamin transport(GO:0015889)
0.7 2.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.7 2.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.7 2.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.7 3.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.6 1.9 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.6 1.7 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.5 2.1 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.4 8.2 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.4 1.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 1.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 1.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.3 5.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 0.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
0.3 1.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 4.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.7 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 1.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 2.3 GO:0060539 diaphragm development(GO:0060539)
0.2 3.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 0.7 GO:0061743 motor learning(GO:0061743)
0.2 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.2 1.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 2.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 0.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 2.2 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 0.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 1.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 2.2 GO:0007530 sex determination(GO:0007530)
0.1 2.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.7 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.1 0.6 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 1.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.6 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.6 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.5 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.9 GO:1902916 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.6 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 1.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 2.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 1.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 1.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.8 GO:0097352 autophagosome maturation(GO:0097352)
0.1 2.4 GO:0051693 actin filament capping(GO:0051693)
0.1 2.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 2.8 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 1.8 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 2.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 1.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 1.0 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:0001824 blastocyst development(GO:0001824)
0.0 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853) positive regulation of brown fat cell differentiation(GO:0090336)
0.0 1.4 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.0 2.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.1 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.7 GO:0007588 excretion(GO:0007588)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.9 GO:0030168 platelet activation(GO:0030168)
0.0 0.8 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.8 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.0 0.2 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0060187 cell pole(GO:0060187)
0.5 2.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.4 1.7 GO:0008623 CHRAC(GO:0008623)
0.4 1.2 GO:0042585 germinal vesicle(GO:0042585)
0.3 2.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 1.1 GO:0031523 Myb complex(GO:0031523)
0.2 8.2 GO:0002102 podosome(GO:0002102)
0.2 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 2.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 3.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 0.7 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 4.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.6 GO:0070469 respiratory chain(GO:0070469)
0.1 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.9 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.6 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 4.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.5 GO:0000776 kinetochore(GO:0000776)
0.1 2.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 6.6 GO:0000792 heterochromatin(GO:0000792)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 3.0 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 5.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 10.5 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.8 3.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.7 2.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.7 2.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 2.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 3.0 GO:0031419 cobalamin binding(GO:0031419)
0.4 6.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.3 3.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 1.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 0.7 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 2.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 5.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.0 GO:0031628 opioid receptor binding(GO:0031628)
0.2 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.7 GO:0019808 polyamine binding(GO:0019808)
0.2 3.3 GO:0008483 transaminase activity(GO:0008483)
0.2 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 5.3 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 2.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 2.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.1 GO:1900750 glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.7 GO:0048185 activin binding(GO:0048185)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 8.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.8 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 2.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 6.6 GO:0051015 actin filament binding(GO:0051015)
0.0 4.5 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.9 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 4.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 12.9 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 4.6 GO:0003779 actin binding(GO:0003779)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.1 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.5 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 2.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 6.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.0 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.7 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.1 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 1.0 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.2 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.7 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 11.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 1.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 4.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 5.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 4.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.8 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines