Motif ID: Gata4

Z-value: 0.636


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_103510874 2.168 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr5_-_73191848 1.846 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr10_-_62342674 1.510 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr1_-_56969827 1.371 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_59948155 1.303 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr16_-_34263179 1.299 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr2_+_4559742 1.279 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr1_-_56969864 1.258 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr1_+_180851131 1.238 ENSMUST00000038091.6
Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr16_-_34262830 1.228 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr10_-_83648631 1.129 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr4_-_82705735 1.058 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr16_+_45093611 1.036 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr5_+_64812336 0.967 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr9_+_66350465 0.938 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr11_+_3330781 0.929 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr10_+_84576626 0.914 ENSMUST00000020223.7
Tcp11l2
t-complex 11 (mouse) like 2
chr8_+_45628176 0.906 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr2_+_65845833 0.850 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_-_7081207 0.837 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr7_-_98112618 0.837 ENSMUST00000153657.1
Myo7a
myosin VIIA
chr7_-_80403315 0.833 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr16_-_34262945 0.818 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr18_+_36952621 0.807 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr4_-_32923455 0.795 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr8_+_45627946 0.794 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr4_+_13751297 0.794 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_71786923 0.751 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr13_+_42681513 0.749 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr12_+_95692212 0.747 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_+_177444653 0.734 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr2_-_52558539 0.725 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr1_+_165788681 0.722 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr16_-_23520579 0.706 ENSMUST00000089883.5
Masp1
mannan-binding lectin serine peptidase 1
chr19_+_58670358 0.690 ENSMUST00000057270.7
Pnlip
pancreatic lipase
chr1_+_165788746 0.689 ENSMUST00000161559.2
Cd247
CD247 antigen
chr4_-_43558386 0.684 ENSMUST00000130353.1
Tln1
talin 1
chr11_+_3330401 0.681 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr13_+_42709482 0.676 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr4_+_102570065 0.655 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr12_-_91849081 0.645 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr4_-_87806276 0.636 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_+_179803376 0.626 ENSMUST00000097454.2
Gm10518
predicted gene 10518
chr2_-_33087169 0.613 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr4_+_102760294 0.596 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr7_+_99535439 0.592 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr13_+_56703504 0.543 ENSMUST00000109874.1
Smad5
SMAD family member 5
chr4_-_87806296 0.525 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr2_-_7081256 0.505 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr15_+_60822947 0.502 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr4_+_102254993 0.482 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chrX_+_93654863 0.475 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr4_-_14621494 0.462 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr2_-_33086366 0.460 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr15_-_50890396 0.459 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr5_-_123666682 0.453 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chrX_+_93675088 0.431 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr3_+_66985680 0.408 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr4_-_14621805 0.404 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr6_-_124768330 0.386 ENSMUST00000135626.1
Eno2
enolase 2, gamma neuronal
chr17_-_33713372 0.383 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr14_-_64455903 0.378 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr15_+_55307743 0.367 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr8_+_45658273 0.359 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr19_-_7295394 0.346 ENSMUST00000025921.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr4_-_138326234 0.343 ENSMUST00000105817.3
ENSMUST00000030536.6
Pink1

PTEN induced putative kinase 1

chr2_+_65845767 0.336 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chrX_+_159840463 0.316 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr2_-_20968881 0.315 ENSMUST00000114594.1
Arhgap21
Rho GTPase activating protein 21
chr17_+_71204647 0.312 ENSMUST00000126681.1
Lpin2
lipin 2
chr8_+_84701430 0.306 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr16_+_91647859 0.274 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son



Son DNA binding protein



chr15_-_77153772 0.268 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr4_+_102254739 0.257 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr16_-_63864114 0.257 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr16_-_46010212 0.256 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_+_43634718 0.240 ENSMUST00000032663.8
Ceacam18
carcinoembryonic antigen-related cell adhesion molecule 18
chr3_-_129755305 0.235 ENSMUST00000029653.2
Egf
epidermal growth factor
chr5_-_121836810 0.227 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr9_-_77251829 0.224 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr10_-_83648713 0.218 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr2_+_72476225 0.212 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr4_-_14621669 0.206 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr1_-_173333503 0.204 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr18_-_24020307 0.198 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr17_-_45593626 0.191 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr14_+_75455957 0.183 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chrX_+_10485121 0.182 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr1_+_151344472 0.182 ENSMUST00000023918.6
ENSMUST00000097543.1
ENSMUST00000111887.3
Ivns1abp


influenza virus NS1A binding protein


chr1_-_162866502 0.181 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr16_+_58670208 0.166 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr1_-_132367879 0.164 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr14_+_55560904 0.163 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr12_-_69893162 0.159 ENSMUST00000049239.7
ENSMUST00000110570.1
Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr5_-_121836852 0.156 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr10_-_59616667 0.156 ENSMUST00000020312.6
Mcu
mitochondrial calcium uniporter
chr15_-_83170168 0.155 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chrX_-_60403947 0.149 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr7_+_110627650 0.144 ENSMUST00000033054.8
Adm
adrenomedullin
chr17_-_28915314 0.142 ENSMUST00000062357.4
4930539E08Rik
RIKEN cDNA 4930539E08 gene
chr11_+_73047783 0.142 ENSMUST00000021135.3
1200014J11Rik
RIKEN cDNA 1200014J11 gene
chr17_+_43389436 0.137 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr6_-_127109517 0.125 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr6_-_122609964 0.097 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chr11_+_88047788 0.095 ENSMUST00000107920.3
Srsf1
serine/arginine-rich splicing factor 1
chr3_+_135826075 0.086 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr2_-_121037048 0.084 ENSMUST00000102490.3
Epb4.2
erythrocyte protein band 4.2
chr1_-_82586781 0.077 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr1_-_14310198 0.064 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr12_-_91746020 0.063 ENSMUST00000166967.1
Ston2
stonin 2
chr3_+_135825648 0.063 ENSMUST00000180196.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr1_-_179803625 0.059 ENSMUST00000027768.7
Ahctf1
AT hook containing transcription factor 1
chr18_+_7869159 0.054 ENSMUST00000170932.1
ENSMUST00000167020.1
Wac

WW domain containing adaptor with coiled-coil

chr2_-_77170592 0.054 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr7_+_28833975 0.053 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr15_-_83170498 0.046 ENSMUST00000162178.1
Cyb5r3
cytochrome b5 reductase 3
chr6_-_55681257 0.044 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr9_+_44379536 0.042 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr7_-_44892358 0.040 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chrX_+_150547375 0.040 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr9_-_77251871 0.034 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr19_-_43524462 0.022 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr4_-_46404224 0.016 ENSMUST00000107764.2
Hemgn
hemogen
chr14_+_55561060 0.014 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr11_+_5009515 0.003 ENSMUST00000101613.2
Ap1b1
adaptor protein complex AP-1, beta 1 subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.5 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.8 GO:0090472 dibasic protein processing(GO:0090472)
0.2 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 2.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.1 GO:0019532 oxalate transport(GO:0019532)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 2.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.8 GO:0050957 equilibrioception(GO:0050957)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 1.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 2.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.2 GO:0007262 STAT protein import into nucleus(GO:0007262) negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.9 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.0 0.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0072513 semicircular canal morphogenesis(GO:0048752) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.8 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.7 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 3.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.8 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 2.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.8 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.2 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 3.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.5 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 1.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides