Motif ID: Vdr

Z-value: 0.997


Transcription factors associated with Vdr:

Gene SymbolEntrez IDGene Name
Vdr ENSMUSG00000022479.9 Vdr



Activity profile for motif Vdr.

activity profile for motif Vdr


Sorted Z-values histogram for motif Vdr

Sorted Z-values for motif Vdr



Network of associatons between targets according to the STRING database.



First level regulatory network of Vdr

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_16752203 3.589 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr10_+_127725392 3.378 ENSMUST00000026466.3
Tac2
tachykinin 2
chr10_+_79716588 2.308 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr5_+_17574268 2.137 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_19310035 1.723 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr3_-_88000350 1.693 ENSMUST00000090971.5
Bcan
brevican
chr7_+_130865835 1.510 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr1_-_162859684 1.450 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr6_+_4903298 1.344 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr4_+_123183722 1.294 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr4_+_148160613 1.243 ENSMUST00000047951.8
Fbxo2
F-box protein 2
chr1_+_170308802 1.234 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr6_+_4902913 1.193 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr11_-_118093702 1.185 ENSMUST00000018719.3
Dnah17
dynein, axonemal, heavy chain 17
chrX_+_136741821 1.179 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr1_-_180483410 1.174 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr4_+_13743424 1.159 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_129121699 1.121 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr3_+_117575268 1.097 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr18_+_36281069 1.090 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr15_-_72546279 1.077 ENSMUST00000044624.6
Kcnk9
potassium channel, subfamily K, member 9
chr7_-_12422751 1.071 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr13_+_94173992 1.042 ENSMUST00000121618.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr3_-_95687846 1.034 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
Adamtsl4


ADAMTS-like 4


chr5_-_8367982 1.018 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr19_+_34192229 1.008 ENSMUST00000054956.8
Stambpl1
STAM binding protein like 1
chr7_-_12422488 0.992 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr8_+_40862379 0.992 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr19_+_44992127 0.972 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_-_116412965 0.962 ENSMUST00000100202.3
ENSMUST00000106398.2
Rnf157

ring finger protein 157

chr7_+_28833975 0.939 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chrX_+_136590841 0.924 ENSMUST00000138047.1
ENSMUST00000145648.1
Tceal3

transcription elongation factor A (SII)-like 3

chr18_+_37484955 0.875 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr4_-_141599835 0.869 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr8_+_13405080 0.861 ENSMUST00000033827.7
Grk1
G protein-coupled receptor kinase 1
chr15_-_65014904 0.841 ENSMUST00000110100.2
Gm21961
predicted gene, 21961
chr11_-_120047070 0.818 ENSMUST00000064307.3
Aatk
apoptosis-associated tyrosine kinase
chr9_-_21248437 0.812 ENSMUST00000122088.1
S1pr5
sphingosine-1-phosphate receptor 5
chr9_+_87144285 0.781 ENSMUST00000113149.1
ENSMUST00000143779.1
ENSMUST00000179313.1
ENSMUST00000049457.7
ENSMUST00000153444.1
Mrap2




melanocortin 2 receptor accessory protein 2




chr2_+_120629113 0.776 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr8_+_34054622 0.767 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr19_+_5740885 0.763 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr1_-_136260873 0.762 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr8_+_122269569 0.761 ENSMUST00000055537.2
Gm22
predicted gene 22
chr2_-_5063996 0.758 ENSMUST00000114996.1
Optn
optineurin
chr7_-_140154712 0.743 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr2_-_5063932 0.726 ENSMUST00000027986.4
Optn
optineurin
chr1_-_162859919 0.718 ENSMUST00000134098.1
ENSMUST00000111518.1
Fmo1

flavin containing monooxygenase 1

chr1_+_134182404 0.714 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr2_+_32741452 0.706 ENSMUST00000131101.1
Sh2d3c
SH2 domain containing 3C
chr15_-_58214882 0.702 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr7_+_126776939 0.695 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chrX_-_85776606 0.692 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
Gyk


glycerol kinase


chr2_+_180042496 0.684 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr6_-_146502141 0.682 ENSMUST00000079573.6
ENSMUST00000139732.1
Itpr2

inositol 1,4,5-triphosphate receptor 2

chr3_-_40846847 0.667 ENSMUST00000026859.5
Mfsd8
major facilitator superfamily domain containing 8
chrX_-_37110257 0.654 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr4_-_42034726 0.649 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr6_-_37442095 0.641 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr7_-_139683797 0.639 ENSMUST00000129990.1
ENSMUST00000130453.1
9330101J02Rik

RIKEN cDNA 9330101J02 gene

chr4_+_42459563 0.639 ENSMUST00000098119.2
Gm3883
predicted gene 3883
chr9_-_107667375 0.634 ENSMUST00000010208.8
Slc38a3
solute carrier family 38, member 3
chr7_+_112953955 0.633 ENSMUST00000182858.1
Rassf10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr3_+_40846970 0.616 ENSMUST00000108078.2
3110057O12Rik
RIKEN cDNA 3110057O12 gene
chr2_+_119897212 0.613 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr11_-_87826023 0.597 ENSMUST00000103177.3
Lpo
lactoperoxidase
chr7_+_4460687 0.577 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr4_+_136286061 0.576 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr5_-_32785585 0.564 ENSMUST00000142779.1
ENSMUST00000061895.9
Pisd

phosphatidylserine decarboxylase

chr16_+_23609895 0.550 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr15_+_82256023 0.544 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr11_-_61175020 0.541 ENSMUST00000041683.8
Usp22
ubiquitin specific peptidase 22
chr1_-_176807124 0.541 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr4_-_149698698 0.533 ENSMUST00000038859.7
ENSMUST00000105690.2
Pik3cd

phosphatidylinositol 3-kinase catalytic delta polypeptide

chr8_-_105289465 0.530 ENSMUST00000171788.1
ENSMUST00000014981.6
4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr14_-_74947865 0.514 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr10_+_57784914 0.497 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr6_-_128143525 0.493 ENSMUST00000032503.5
ENSMUST00000112173.1
Tspan9

tetraspanin 9

chr10_-_79874565 0.470 ENSMUST00000167250.1
ENSMUST00000092325.4
BC005764

cDNA sequence BC005764

chr5_-_39644634 0.462 ENSMUST00000053116.6
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr7_-_4778141 0.461 ENSMUST00000094892.5
Il11
interleukin 11
chr11_+_82952095 0.448 ENSMUST00000108158.2
ENSMUST00000067443.2
Slfn5

schlafen 5

chr6_-_146502099 0.448 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr10_-_81430966 0.446 ENSMUST00000117966.1
Nfic
nuclear factor I/C
chr10_+_57784859 0.444 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr17_-_7827289 0.435 ENSMUST00000167580.1
ENSMUST00000169126.1
Fndc1

fibronectin type III domain containing 1

chr5_-_39644597 0.434 ENSMUST00000152057.1
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr12_-_84361802 0.423 ENSMUST00000021659.1
ENSMUST00000065536.2
Fam161b

family with sequence similarity 161, member B

chr7_+_13398115 0.405 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr10_+_7792891 0.401 ENSMUST00000015901.4
Ppil4
peptidylprolyl isomerase (cyclophilin)-like 4
chr18_-_7004717 0.396 ENSMUST00000079788.4
Mkx
mohawk homeobox
chr7_-_141429351 0.389 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr19_-_23075853 0.386 ENSMUST00000181623.1
C330002G04Rik
RIKEN cDNA C330002G04 gene
chr1_+_135729147 0.383 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr3_-_146812951 0.379 ENSMUST00000102515.3
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr14_-_20794009 0.377 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr14_+_4110526 0.371 ENSMUST00000170207.1
Gm8108
predicted gene 8108
chr15_+_82274935 0.371 ENSMUST00000023095.6
Sept3
septin 3
chr7_-_141429433 0.370 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr19_-_30549516 0.369 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr17_+_33929514 0.366 ENSMUST00000047503.9
Rgl2
ral guanine nucleotide dissociation stimulator-like 2
chr5_-_151190154 0.358 ENSMUST00000062015.8
ENSMUST00000110483.2
Stard13

StAR-related lipid transfer (START) domain containing 13

chr9_-_86880647 0.353 ENSMUST00000167014.1
Snap91
synaptosomal-associated protein 91
chr6_+_125215551 0.350 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr19_-_6909599 0.346 ENSMUST00000173091.1
Prdx5
peroxiredoxin 5
chr15_+_101412402 0.344 ENSMUST00000068904.8
Krt7
keratin 7
chr4_+_59003121 0.342 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr3_+_95160449 0.342 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr7_+_127800844 0.341 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr2_-_32741016 0.330 ENSMUST00000009695.2
6330409D20Rik
RIKEN cDNA 6330409D20 gene
chr2_+_140152043 0.328 ENSMUST00000104994.2
Gm17374
predicted gene, 17374
chr4_-_118180043 0.323 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr9_+_53771499 0.319 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr3_+_41024369 0.318 ENSMUST00000099121.3
Larp1b
La ribonucleoprotein domain family, member 1B
chr15_+_82275197 0.317 ENSMUST00000116423.1
Sept3
septin 3
chrX_+_48108912 0.317 ENSMUST00000114998.1
ENSMUST00000115000.3
Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

chr4_-_118179946 0.312 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr14_-_45477856 0.300 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr7_-_3720382 0.299 ENSMUST00000078451.6
Pirb
paired Ig-like receptor B
chr11_-_3722189 0.296 ENSMUST00000102950.3
ENSMUST00000101632.3
Osbp2

oxysterol binding protein 2

chr10_+_40629987 0.295 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr4_-_42459176 0.294 ENSMUST00000098118.1
Gm10597
predicted gene 10597
chr15_-_97814830 0.283 ENSMUST00000121514.1
Hdac7
histone deacetylase 7
chr13_+_105443693 0.281 ENSMUST00000022235.4
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
chr2_+_91259822 0.275 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr1_+_134182150 0.264 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr11_+_3514861 0.261 ENSMUST00000094469.4
Selm
selenoprotein M
chr19_+_10204014 0.259 ENSMUST00000040372.7
Tmem258
transmembrane protein 258
chr5_-_121502980 0.257 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr11_+_83299005 0.253 ENSMUST00000176944.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr7_+_5051515 0.244 ENSMUST00000069324.5
Zfp580
zinc finger protein 580
chr9_-_119322421 0.243 ENSMUST00000040853.4
Oxsr1
oxidative-stress responsive 1
chr4_-_19708922 0.241 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr8_-_105255100 0.239 ENSMUST00000093217.2
ENSMUST00000161745.2
ENSMUST00000136822.2
B3gnt9


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9


chr4_+_156215920 0.237 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr4_-_46413486 0.235 ENSMUST00000071096.2
Hemgn
hemogen
chr5_-_120588613 0.223 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr4_-_43578824 0.213 ENSMUST00000030189.7
Gba2
glucosidase beta 2
chr1_+_130717320 0.213 ENSMUST00000049813.4
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr12_+_76765527 0.211 ENSMUST00000137826.1
ENSMUST00000041262.7
ENSMUST00000126408.1
ENSMUST00000110399.2
Fntb
Churc1


farnesyltransferase, CAAX box, beta
churchill domain containing 1


chr5_+_101765120 0.209 ENSMUST00000031273.8
Cds1
CDP-diacylglycerol synthase 1
chr15_-_79328201 0.206 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr8_-_85080652 0.201 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr10_-_81545175 0.195 ENSMUST00000043604.5
Gna11
guanine nucleotide binding protein, alpha 11
chr4_+_42035113 0.193 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr10_-_78298162 0.192 ENSMUST00000105389.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_+_123183456 0.192 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr18_-_12941777 0.191 ENSMUST00000122175.1
Osbpl1a
oxysterol binding protein-like 1A
chr10_+_89744988 0.185 ENSMUST00000020112.5
Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr2_-_30415767 0.181 ENSMUST00000102855.1
ENSMUST00000028207.6
Crat

carnitine acetyltransferase

chr17_-_36271877 0.180 ENSMUST00000042717.6
Trim39
tripartite motif-containing 39
chr15_-_76918010 0.176 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chrX_+_71215006 0.174 ENSMUST00000101501.3
ENSMUST00000061970.5
ENSMUST00000025391.4
ENSMUST00000114621.1
ENSMUST00000033700.5
Mtm1




X-linked myotubular myopathy gene 1




chr7_+_19282613 0.170 ENSMUST00000032559.9
Rtn2
reticulon 2 (Z-band associated protein)
chr18_+_38418946 0.169 ENSMUST00000025293.3
Ndfip1
Nedd4 family interacting protein 1
chr5_+_139389785 0.168 ENSMUST00000100514.2
Gpr146
G protein-coupled receptor 146
chr14_-_30923754 0.164 ENSMUST00000006697.8
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr19_+_5474681 0.163 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr16_-_18413452 0.157 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt

catechol-O-methyltransferase

chr2_-_30415302 0.156 ENSMUST00000132981.2
ENSMUST00000129494.1
Crat

carnitine acetyltransferase

chr4_-_42528175 0.154 ENSMUST00000180201.1
Gm13298
predicted gene 13298
chr15_-_79328154 0.153 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chr17_-_33713372 0.150 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr7_+_16098458 0.149 ENSMUST00000006181.6
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr18_-_12941801 0.148 ENSMUST00000074352.4
Osbpl1a
oxysterol binding protein-like 1A
chr17_+_83706137 0.142 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3


metastasis associated 3


chrX_+_38600626 0.139 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr7_+_5080214 0.136 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr3_+_106547693 0.133 ENSMUST00000117469.1
ENSMUST00000067630.6
ENSMUST00000134396.1
ENSMUST00000144746.1
ENSMUST00000121034.1
ENSMUST00000029507.6
ENSMUST00000132923.1
ENSMUST00000151465.1
Dram2







DNA-damage regulated autophagy modulator 2







chr2_+_126707319 0.133 ENSMUST00000028841.7
ENSMUST00000110416.2
Usp8

ubiquitin specific peptidase 8

chr10_-_80102653 0.132 ENSMUST00000042771.7
Sbno2
strawberry notch homolog 2 (Drosophila)
chr5_-_148371525 0.130 ENSMUST00000138596.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_+_54304180 0.128 ENSMUST00000108904.3
ENSMUST00000108905.3
Acsl6

acyl-CoA synthetase long-chain family member 6

chr4_-_153975038 0.127 ENSMUST00000030893.2
Dffb
DNA fragmentation factor, beta subunit
chr6_-_28397999 0.121 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chrX_+_7878298 0.121 ENSMUST00000033495.8
Pim2
proviral integration site 2
chr9_-_50693799 0.121 ENSMUST00000120622.1
Dixdc1
DIX domain containing 1
chr10_+_52690496 0.117 ENSMUST00000105473.2
Slc35f1
solute carrier family 35, member F1
chr4_-_19570073 0.114 ENSMUST00000029885.4
Cpne3
copine III
chr4_+_126148457 0.112 ENSMUST00000106150.2
Eva1b
eva-1 homolog B (C. elegans)
chr11_-_115187827 0.111 ENSMUST00000103041.1
Nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr8_-_70897407 0.109 ENSMUST00000054220.8
Rpl18a
ribosomal protein L18A
chr13_-_12106945 0.107 ENSMUST00000021750.7
ENSMUST00000170156.2
Ryr2

ryanodine receptor 2, cardiac

chr12_-_48559971 0.098 ENSMUST00000169406.1
Gm1818
predicted gene 1818
chr17_+_56990264 0.096 ENSMUST00000002735.7
Clpp
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit
chr1_+_173420567 0.096 ENSMUST00000173023.1
Aim2
absent in melanoma 2
chr8_+_60632818 0.092 ENSMUST00000161421.1
Mfap3l
microfibrillar-associated protein 3-like
chr9_-_75441652 0.089 ENSMUST00000181896.1
A130057D12Rik
RIKEN cDNA A130057D12 gene
chr4_-_43578636 0.087 ENSMUST00000130443.1
Gba2
glucosidase beta 2
chr4_-_155869394 0.086 ENSMUST00000105586.1
ENSMUST00000030950.1
Gltpd1

glycolipid transfer protein domain containing 1

chr6_-_70792155 0.083 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr2_-_165360136 0.083 ENSMUST00000073062.7
Zfp663
zinc finger protein 663
chr1_-_171287916 0.081 ENSMUST00000111305.1
Usp21
ubiquitin specific peptidase 21
chr8_+_4243264 0.079 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chr11_+_87853207 0.078 ENSMUST00000038196.6
Mks1
Meckel syndrome, type 1
chr11_-_83298873 0.069 ENSMUST00000175741.1
ENSMUST00000176518.1
Pex12

peroxisomal biogenesis factor 12

chr4_-_140665891 0.068 ENSMUST00000069623.5
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr8_-_70353243 0.068 ENSMUST00000075666.6
Upf1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr12_-_54656496 0.066 ENSMUST00000056228.6
Sptssa
serine palmitoyltransferase, small subunit A
chr2_-_30415509 0.066 ENSMUST00000134120.1
ENSMUST00000102854.3
Crat

carnitine acetyltransferase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.8 3.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.7 3.6 GO:0070459 prolactin secretion(GO:0070459)
0.5 2.3 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.4 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 1.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 2.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 1.0 GO:1902022 L-lysine transport(GO:1902022)
0.3 0.9 GO:0016056 photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.3 0.8 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 0.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.2 0.7 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 2.5 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.6 GO:0015817 histidine transport(GO:0015817)
0.1 1.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.1 1.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.4 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.9 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.5 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.4 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.8 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.8 2.3 GO:0098855 HCN channel complex(GO:0098855)
0.5 2.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.7 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.4 GO:0070820 tertiary granule(GO:0070820)
0.1 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.7 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.0 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.6 2.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 2.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 0.8 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 1.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 0.6 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.2 1.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 2.1 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.6 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.3 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.1 0.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.5 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 0.9 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 3.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.6 PID_FOXO_PATHWAY FoxO family signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.6 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.7 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.3 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.1 2.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.3 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME_IL_3_5_AND_GM_CSF_SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane