Motif ID: Scrt2

Z-value: 1.415


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.474.6e-02Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_30973399 7.460 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr7_-_30973367 6.992 ENSMUST00000108116.3
Lsr
lipolysis stimulated lipoprotein receptor
chr7_-_30973464 6.941 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr10_+_26229707 6.789 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr10_+_56377300 6.785 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr9_+_91368811 5.980 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368970 5.203 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr7_-_25250720 3.631 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chrX_-_72274747 3.545 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr9_-_27155418 3.527 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr15_-_98004634 3.395 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr3_+_34649987 3.318 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr2_-_164443177 3.259 ENSMUST00000017153.3
Sdc4
syndecan 4
chr13_+_23756937 3.256 ENSMUST00000102965.2
Hist1h4b
histone cluster 1, H4b
chr3_-_33143227 3.220 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr2_+_31950257 3.209 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr8_+_31187317 2.827 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr1_-_133424377 2.771 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr16_+_16213318 2.768 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr11_-_100355383 2.540 ENSMUST00000146878.2
Hap1
huntingtin-associated protein 1
chr4_+_98923908 2.440 ENSMUST00000169053.1
Usp1
ubiquitin specific peptidase 1
chr9_+_59656368 2.407 ENSMUST00000034834.9
ENSMUST00000163694.2
Pkm

pyruvate kinase, muscle

chr4_+_98923810 2.277 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr15_-_36598019 2.259 ENSMUST00000155116.1
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr11_-_55419898 2.197 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr4_+_98923845 2.181 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr3_-_33143025 2.144 ENSMUST00000108226.1
Pex5l
peroxisomal biogenesis factor 5-like
chr9_-_21852603 2.032 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr4_-_129189646 1.949 ENSMUST00000106059.1
S100pbp
S100P binding protein
chr2_+_92915080 1.912 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr3_+_81036360 1.800 ENSMUST00000029652.3
Pdgfc
platelet-derived growth factor, C polypeptide
chr11_+_71749914 1.798 ENSMUST00000150531.1
Wscd1
WSC domain containing 1
chr3_+_130180882 1.709 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr6_-_120357422 1.661 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr4_-_129189512 1.646 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
S100pbp


S100P binding protein


chr6_-_120357342 1.596 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr4_+_15265798 1.542 ENSMUST00000062684.8
Tmem64
transmembrane protein 64
chr12_-_91779129 1.531 ENSMUST00000170077.1
Ston2
stonin 2
chr6_-_23839137 1.520 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr2_-_168590191 1.485 ENSMUST00000029057.6
ENSMUST00000074618.3
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr15_-_50889691 1.467 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr3_-_108840477 1.422 ENSMUST00000106596.3
ENSMUST00000102621.4
Stxbp3a

syntaxin binding protein 3A

chr6_-_53820764 1.375 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr2_-_168590315 1.299 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr6_-_120357440 1.276 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr12_-_40037387 1.210 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr16_+_44347121 1.206 ENSMUST00000050897.6
Spice1
spindle and centriole associated protein 1
chr11_+_53770458 1.195 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr3_+_121426495 1.193 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr5_-_137116177 1.066 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr12_+_113098199 1.051 ENSMUST00000009099.6
ENSMUST00000109723.1
ENSMUST00000109726.1
ENSMUST00000109727.2
ENSMUST00000069690.4
Mta1




metastasis associated 1




chr8_-_70700070 1.049 ENSMUST00000116172.1
Gm11175
predicted gene 11175
chr5_-_138171248 1.047 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_170131156 1.033 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr14_+_54883377 1.030 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chr5_-_137611372 0.991 ENSMUST00000054564.6
Pcolce
procollagen C-endopeptidase enhancer protein
chr4_-_129189600 0.973 ENSMUST00000117497.1
ENSMUST00000117350.1
S100pbp

S100P binding protein

chr11_+_76945719 0.908 ENSMUST00000125145.1
Blmh
bleomycin hydrolase
chr2_+_91257323 0.889 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chrX_-_101085352 0.879 ENSMUST00000101362.1
ENSMUST00000073927.4
Slc7a3

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

chr15_+_31276491 0.826 ENSMUST00000068987.5
Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr12_+_78748947 0.826 ENSMUST00000082024.5
Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr15_+_34306666 0.813 ENSMUST00000163455.2
ENSMUST00000022947.5
Matn2

matrilin 2

chr7_-_65370908 0.781 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr7_+_107370728 0.779 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chrX_+_85048309 0.758 ENSMUST00000113991.1
ENSMUST00000113992.2
Dmd

dystrophin, muscular dystrophy

chrX_-_104671048 0.748 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr10_-_61979073 0.723 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr2_+_91256813 0.711 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr15_-_50890041 0.694 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_45830776 0.676 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr3_-_89101907 0.670 ENSMUST00000081848.8
Fdps
farnesyl diphosphate synthetase
chr9_-_22117123 0.652 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr13_-_81633119 0.607 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr7_+_126847908 0.590 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr5_-_137611429 0.579 ENSMUST00000031731.7
Pcolce
procollagen C-endopeptidase enhancer protein
chr9_+_6168638 0.563 ENSMUST00000058692.7
Pdgfd
platelet-derived growth factor, D polypeptide
chr11_+_50376982 0.544 ENSMUST00000109142.1
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
chrX_+_153139941 0.541 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr17_-_56183887 0.516 ENSMUST00000019723.7
D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chr4_-_134012381 0.502 ENSMUST00000176113.1
Lin28a
lin-28 homolog A (C. elegans)
chr5_-_123684275 0.434 ENSMUST00000111561.1
Clip1
CAP-GLY domain containing linker protein 1
chr17_-_25844417 0.422 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr1_+_120602405 0.358 ENSMUST00000079721.7
En1
engrailed 1
chr8_-_71537402 0.339 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr5_-_100373484 0.334 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr3_-_67375163 0.334 ENSMUST00000166353.1
Gm17402
predicted gene, 17402
chr4_-_151044564 0.329 ENSMUST00000103204.4
Per3
period circadian clock 3
chr6_-_148831448 0.276 ENSMUST00000048418.7
Ipo8
importin 8
chr5_-_138171216 0.230 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_-_98206151 0.212 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr2_-_30830333 0.195 ENSMUST00000041726.3
Asb6
ankyrin repeat and SOCS box-containing 6
chr5_+_66676098 0.188 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr19_-_4839286 0.179 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr11_+_103649498 0.168 ENSMUST00000057870.2
Rprml
reprimo-like
chr4_+_149518216 0.157 ENSMUST00000030839.6
Ctnnbip1
catenin beta interacting protein 1
chr5_-_138171813 0.155 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr18_-_3281036 0.153 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr4_+_135759705 0.149 ENSMUST00000105854.1
Myom3
myomesin family, member 3
chr7_+_102223021 0.146 ENSMUST00000156529.1
ENSMUST00000138479.1
ENSMUST00000126914.1
ENSMUST00000033292.7
ENSMUST00000146559.1
Pgap2




post-GPI attachment to proteins 2




chr2_-_32260138 0.108 ENSMUST00000002625.8
Uck1
uridine-cytidine kinase 1
chr1_-_156939387 0.090 ENSMUST00000171292.1
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr5_-_123684289 0.079 ENSMUST00000111564.1
ENSMUST00000063905.5
Clip1

CAP-GLY domain containing linker protein 1

chr6_-_90716489 0.051 ENSMUST00000101153.3
Iqsec1
IQ motif and Sec7 domain 1
chr4_+_125066672 0.047 ENSMUST00000052183.6
Snip1
Smad nuclear interacting protein 1
chr1_-_156939626 0.033 ENSMUST00000063199.6
ENSMUST00000027886.7
ENSMUST00000172057.1
Ralgps2


Ral GEF with PH domain and SH3 binding motif 2


chr1_-_79440039 0.030 ENSMUST00000049972.4
Scg2
secretogranin II
chr4_+_129189760 0.023 ENSMUST00000106054.2
ENSMUST00000001365.2
Yars

tyrosyl-tRNA synthetase

chr7_+_90130227 0.022 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr17_-_55712571 0.017 ENSMUST00000086876.5
Pot1b
protection of telomeres 1B
chr15_+_6422240 0.004 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.3 6.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.9 2.8 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.8 5.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.7 3.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.7 3.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.6 6.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.5 1.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5 2.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.5 3.3 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.5 2.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 1.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4 2.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.4 1.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.4 3.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 3.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 1.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 2.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.2 0.6 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.2 0.9 GO:0015822 ornithine transport(GO:0015822)
0.2 2.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 1.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 3.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 0.9 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 3.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 2.8 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 3.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.7 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 2.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 2.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 1.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 1.2 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 1.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.8 GO:0048678 response to axon injury(GO:0048678)
0.0 0.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 1.1 GO:0007569 cell aging(GO:0007569)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 21.4 GO:0061689 tricellular tight junction(GO:0061689)
1.3 5.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.7 3.5 GO:0033010 paranodal junction(GO:0033010)
0.6 6.8 GO:0005916 fascia adherens(GO:0005916)
0.5 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 3.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 2.8 GO:0030057 desmosome(GO:0030057)
0.2 1.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 3.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 4.0 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 3.7 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0070382 exocytic vesicle(GO:0070382)
0.0 3.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 4.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
1.6 3.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.3 21.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
1.1 5.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.8 2.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.7 2.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.7 3.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 2.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 0.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 2.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 3.8 GO:0035198 miRNA binding(GO:0035198)
0.2 3.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 2.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.8 GO:0071253 connexin binding(GO:0071253)
0.1 8.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 4.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.0 GO:0051400 BH domain binding(GO:0051400)
0.1 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 3.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 3.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 17.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.3 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 3.5 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 6.9 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 5.8 NABA_COLLAGENS Genes encoding collagen proteins
0.1 3.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 1.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 2.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.9 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 6.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 7.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 2.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 3.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production