Motif ID: Pax8

Z-value: 0.456


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475596_244756050.243.3e-01Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_66860458 1.555 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr7_+_6961160 1.283 ENSMUST00000054055.6
Usp29
ubiquitin specific peptidase 29
chr13_-_66852017 0.891 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr18_-_12121460 0.582 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
Tmem241


transmembrane protein 241


chr9_+_32116040 0.481 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr4_+_103313806 0.465 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr7_+_112742025 0.435 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr11_-_69801716 0.433 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr9_-_103230415 0.417 ENSMUST00000035158.9
Trf
transferrin
chr7_-_29906087 0.384 ENSMUST00000053521.8
Zfp27
zinc finger protein 27
chr9_+_109052828 0.377 ENSMUST00000124432.1
Shisa5
shisa homolog 5 (Xenopus laevis)
chr12_+_71048338 0.373 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr1_+_65186727 0.340 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr2_+_128967383 0.301 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr11_+_78499087 0.252 ENSMUST00000017488.4
Vtn
vitronectin
chr4_+_6191093 0.211 ENSMUST00000029907.5
Ubxn2b
UBX domain protein 2B
chr17_+_45555693 0.201 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr13_-_62777089 0.176 ENSMUST00000167516.2
Gm5141
predicted gene 5141
chr13_-_25270076 0.160 ENSMUST00000057866.6
Nrsn1
neurensin 1
chr8_-_64849818 0.160 ENSMUST00000034017.7
Klhl2
kelch-like 2, Mayven
chr19_+_46075842 0.151 ENSMUST00000165017.1
Nolc1
nucleolar and coiled-body phosphoprotein 1
chr12_-_20900867 0.145 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr4_+_156215920 0.114 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr4_+_59805829 0.112 ENSMUST00000030080.6
Snx30
sorting nexin family member 30
chr2_+_177508570 0.109 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chrX_-_105391726 0.097 ENSMUST00000142109.1
5330434G04Rik
RIKEN cDNA 5330434G04 gene
chr11_+_24080664 0.086 ENSMUST00000118955.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr5_+_100196611 0.085 ENSMUST00000066813.1
Gm9932
predicted gene 9932
chr13_-_62607499 0.081 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr13_-_62520451 0.070 ENSMUST00000082203.6
ENSMUST00000101547.4
Zfp934

zinc finger protein 934

chr17_+_21691860 0.068 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr16_-_30587537 0.067 ENSMUST00000117363.2
Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chr7_+_12897800 0.058 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
Zscan22



zinc finger and SCAN domain containing 22



chrX_-_105391770 0.038 ENSMUST00000136406.1
ENSMUST00000150604.1
5330434G04Rik

RIKEN cDNA 5330434G04 gene

chrX_-_7572843 0.022 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr9_-_103230262 0.018 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
Trf

Gm20425
transferrin

predicted gene 20425
chr1_+_74542881 0.004 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 0.6 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.1 0.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 0.4 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0032329 serine transport(GO:0032329)
0.0 0.4 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.3 GO:0097421 liver regeneration(GO:0097421)
0.0 0.1 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0032288 myelin assembly(GO:0032288)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.3 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression