Motif ID: Rara
Z-value: 0.855

Transcription factors associated with Rara:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Rara | ENSMUSG00000037992.10 | Rara |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Rara | mm10_v2_chr11_+_98927785_98927818 | 0.46 | 5.3e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.8 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
0.3 | 1.1 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.3 | 0.8 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
0.2 | 0.6 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.2 | 1.0 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.2 | 0.6 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.2 | 0.6 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.2 | 1.1 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
0.2 | 0.7 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.2 | 0.6 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
0.1 | 0.3 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 1.6 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.1 | 2.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.4 | GO:0042228 | interleukin-8 biosynthetic process(GO:0042228) |
0.0 | 0.6 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.0 | 0.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.5 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
0.0 | 0.2 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.0 | 0.7 | GO:0010883 | regulation of lipid storage(GO:0010883) |
0.0 | 0.4 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.1 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.2 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.0 | 0.1 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.0 | 0.5 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.3 | GO:1903204 | negative regulation of oxidative stress-induced neuron death(GO:1903204) |
0.0 | 0.2 | GO:1902170 | cellular response to reactive nitrogen species(GO:1902170) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.7 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.1 | 1.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 0.7 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.1 | 0.5 | GO:0097513 | myosin II filament(GO:0097513) |
0.0 | 0.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.2 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.0 | 1.7 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 1.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.4 | 2.7 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.2 | 0.7 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.1 | 1.1 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.1 | 0.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 1.6 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 2.8 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 1.5 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 0.4 | GO:0050700 | CARD domain binding(GO:0050700) |
0.1 | 1.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 0.6 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.7 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.1 | 2.3 | GO:0022839 | ion gated channel activity(GO:0022839) |
0.1 | 0.2 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.0 | 0.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.7 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 1.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.2 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.0 | 0.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.8 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 1.5 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.9 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.7 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 1.4 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 1.6 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 4.1 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.9 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.5 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 0.4 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
0.0 | 0.2 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 0.1 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.0 | 0.5 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.3 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |