Motif ID: Nkx6-1_Evx1_Hesx1
Z-value: 0.661



Transcription factors associated with Nkx6-1_Evx1_Hesx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Evx1 | ENSMUSG00000005503.8 | Evx1 |
Hesx1 | ENSMUSG00000040726.8 | Hesx1 |
Nkx6-1 | ENSMUSG00000035187.8 | Nkx6-1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nkx6-1 | mm10_v2_chr5_-_101665195_101665226 | -0.08 | 7.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.3 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
0.7 | 2.2 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.7 | 2.8 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.7 | 4.0 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.6 | 2.5 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.5 | 1.8 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.4 | 1.1 | GO:0050975 | sensory perception of touch(GO:0050975) |
0.3 | 4.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.3 | 0.9 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.3 | 1.2 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.3 | 2.4 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.3 | 0.3 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.3 | 1.7 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.3 | 2.0 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.3 | 1.4 | GO:0070459 | prolactin secretion(GO:0070459) |
0.3 | 1.9 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.3 | 1.5 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
0.3 | 0.5 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
0.2 | 0.7 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.2 | 0.6 | GO:0019085 | early viral transcription(GO:0019085) |
0.2 | 1.8 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.2 | 0.4 | GO:0009838 | abscission(GO:0009838) |
0.2 | 1.4 | GO:0019532 | oxalate transport(GO:0019532) |
0.2 | 0.6 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.2 | 0.5 | GO:1903002 | negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) |
0.2 | 0.7 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.2 | 0.5 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
0.2 | 0.8 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.2 | 0.5 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
0.2 | 1.1 | GO:0030242 | pexophagy(GO:0030242) |
0.2 | 0.8 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.2 | 1.7 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.1 | 0.4 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.1 | 0.4 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.1 | 0.3 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
0.1 | 0.4 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 0.7 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375) |
0.1 | 0.7 | GO:0051593 | response to folic acid(GO:0051593) |
0.1 | 0.4 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
0.1 | 0.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.1 | 0.4 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
0.1 | 0.5 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
0.1 | 1.3 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.1 | 1.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 2.3 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.1 | 0.5 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 2.5 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.1 | 0.2 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 0.4 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) dibasic protein processing(GO:0090472) |
0.1 | 0.9 | GO:0097475 | motor neuron migration(GO:0097475) |
0.1 | 0.5 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
0.1 | 0.5 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
0.1 | 0.5 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.1 | 0.5 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.1 | 0.4 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
0.1 | 0.5 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.1 | 0.4 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
0.1 | 1.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.1 | 0.2 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) vein smooth muscle contraction(GO:0014826) |
0.1 | 0.2 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
0.1 | 1.3 | GO:0001553 | luteinization(GO:0001553) |
0.1 | 0.9 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.4 | GO:0097646 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.1 | 0.2 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
0.1 | 0.5 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
0.1 | 0.2 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.1 | 0.2 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.1 | 0.3 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.1 | 0.6 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 0.3 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.1 | 0.2 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.1 | 0.2 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
0.1 | 0.5 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
0.1 | 0.2 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
0.1 | 1.1 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
0.1 | 0.6 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.1 | 0.9 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.1 | 0.8 | GO:0032570 | response to progesterone(GO:0032570) |
0.1 | 0.7 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 0.2 | GO:0071336 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
0.1 | 0.2 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.1 | 4.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.1 | 1.0 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
0.1 | 0.3 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.1 | 0.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.1 | 1.3 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.1 | 0.4 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
0.1 | 0.2 | GO:0072092 | ureteric bud invasion(GO:0072092) |
0.1 | 0.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.1 | 0.5 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.3 | GO:0032264 | IMP salvage(GO:0032264) |
0.0 | 1.0 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.0 | 0.2 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
0.0 | 0.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 1.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 1.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.4 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.0 | 0.2 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.0 | 0.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.0 | 1.1 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 0.5 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.0 | 0.2 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
0.0 | 0.3 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.0 | 1.1 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.0 | 0.2 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
0.0 | 2.2 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 1.7 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 2.0 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 0.2 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
0.0 | 0.2 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
0.0 | 0.4 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.5 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 1.7 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.0 | 1.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.5 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
0.0 | 0.4 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.0 | 0.4 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.0 | 0.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.2 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.0 | 0.4 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.0 | 0.2 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.0 | 2.1 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 1.3 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.7 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
0.0 | 0.3 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.2 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.0 | 0.2 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
0.0 | 0.3 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.0 | 0.1 | GO:0031038 | myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) |
0.0 | 0.1 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
0.0 | 0.6 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 0.3 | GO:0045579 | positive regulation of B cell differentiation(GO:0045579) |
0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.6 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
0.0 | 0.0 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.0 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 2.1 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.0 | 0.6 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.0 | 0.6 | GO:0061050 | regulation of cell growth involved in cardiac muscle cell development(GO:0061050) |
0.0 | 0.3 | GO:0032414 | positive regulation of ion transmembrane transporter activity(GO:0032414) |
0.0 | 0.1 | GO:2000158 | regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158) |
0.0 | 0.1 | GO:2000794 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794) |
0.0 | 0.1 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.0 | 0.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.0 | 0.3 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
0.0 | 0.2 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.0 | 0.4 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.0 | 0.6 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 1.1 | GO:0015807 | L-amino acid transport(GO:0015807) |
0.0 | 0.3 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.1 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
0.0 | 0.4 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.0 | 0.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.0 | 0.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.0 | 0.5 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 1.3 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 1.6 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
0.0 | 0.4 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.2 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.1 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
0.0 | 0.2 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
0.0 | 0.3 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 0.0 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) mesenchymal cell proliferation involved in lung development(GO:0060916) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) |
0.0 | 1.8 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.2 | GO:0046339 | phosphatidic acid biosynthetic process(GO:0006654) diacylglycerol metabolic process(GO:0046339) |
0.0 | 0.3 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.1 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.0 | 0.3 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.1 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.0 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.3 | 1.4 | GO:0097487 | vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487) |
0.3 | 0.9 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.3 | 2.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 4.0 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.2 | 2.9 | GO:0005614 | interstitial matrix(GO:0005614) |
0.2 | 0.5 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.2 | 0.7 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.1 | 2.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.1 | 1.7 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 0.6 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.1 | 0.3 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
0.1 | 0.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.1 | 1.0 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.1 | 3.7 | GO:0031672 | A band(GO:0031672) |
0.1 | 1.1 | GO:0098839 | postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634) |
0.1 | 0.3 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.8 | GO:0001739 | sex chromatin(GO:0001739) |
0.1 | 0.4 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.1 | 0.5 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 1.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.1 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 1.5 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 0.3 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.1 | 0.5 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 0.5 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 0.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.0 | 0.4 | GO:0090543 | ESCRT III complex(GO:0000815) Flemming body(GO:0090543) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.2 | GO:0031523 | Myb complex(GO:0031523) |
0.0 | 0.3 | GO:0051286 | cell tip(GO:0051286) |
0.0 | 3.0 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 0.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 0.2 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 1.3 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.7 | GO:0070822 | Sin3-type complex(GO:0070822) |
0.0 | 1.7 | GO:0034704 | calcium channel complex(GO:0034704) |
0.0 | 2.7 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.9 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.8 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.4 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 1.3 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 1.2 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.2 | GO:0097443 | sorting endosome(GO:0097443) |
0.0 | 1.5 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 1.4 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.5 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.0 | 0.2 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
0.0 | 4.7 | GO:0030427 | site of polarized growth(GO:0030427) |
0.0 | 0.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 2.7 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.2 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.0 | 1.8 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 0.9 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 0.1 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.0 | 0.0 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.0 | 0.5 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 2.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.2 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.8 | GO:0030424 | axon(GO:0030424) |
0.0 | 1.4 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 0.2 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.4 | GO:0043679 | axon terminus(GO:0043679) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 4.0 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.5 | 2.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.5 | 1.4 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.3 | 2.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.3 | 1.7 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.3 | 1.2 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.2 | 0.7 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.2 | 1.8 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.2 | 0.7 | GO:0098809 | nitrite reductase activity(GO:0098809) |
0.2 | 1.8 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.2 | 0.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.2 | 1.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.2 | 0.5 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.2 | 1.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.2 | 1.0 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.2 | 0.5 | GO:0019966 | C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120) |
0.1 | 0.7 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.1 | 2.0 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 0.6 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 0.5 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.1 | 0.4 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.1 | 1.4 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.1 | 0.6 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.1 | 0.9 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.1 | 0.8 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.1 | 2.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 0.8 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 0.5 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.1 | 0.6 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.4 | GO:0051378 | serotonin binding(GO:0051378) |
0.1 | 4.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 0.3 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.1 | 0.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 2.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 0.8 | GO:0038191 | neuropilin binding(GO:0038191) |
0.1 | 2.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.2 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.1 | 0.2 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.1 | 0.3 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.1 | 0.6 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.1 | 0.5 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 0.4 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.1 | 1.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 2.1 | GO:0001968 | fibronectin binding(GO:0001968) |
0.1 | 0.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.1 | 1.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 0.3 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
0.1 | 2.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 1.1 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 2.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 0.2 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.1 | 0.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.1 | 0.5 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.1 | 0.2 | GO:0036033 | mediator complex binding(GO:0036033) |
0.1 | 0.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 1.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.1 | 0.4 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.0 | 2.8 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.1 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.0 | 0.3 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 1.9 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.5 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.2 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.0 | 0.2 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
0.0 | 0.3 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.3 | GO:0035004 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004) |
0.0 | 0.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.5 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 0.1 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.0 | 0.2 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.0 | 0.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.0 | 0.1 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.0 | 0.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
0.0 | 0.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 0.7 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.1 | GO:0004534 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534) |
0.0 | 0.2 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.0 | 0.9 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 1.1 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 0.7 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 7.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.1 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.0 | 0.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 5.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 4.9 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.1 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.0 | 0.8 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
0.0 | 0.9 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.1 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.0 | 0.2 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.0 | 0.3 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.4 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.0 | 1.0 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 0.2 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.0 | 0.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 1.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.0 | 0.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.0 | 0.8 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 1.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 0.0 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.0 | 0.4 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.1 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.0 | 0.0 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 0.7 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.2 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 6.1 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.1 | 4.9 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.1 | 4.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.1 | 1.8 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.1 | 1.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.2 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
0.0 | 2.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 1.3 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.5 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.0 | 1.8 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 1.1 | ST_ADRENERGIC | Adrenergic Pathway |
0.0 | 1.0 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 1.5 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.7 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.0 | 0.7 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 0.7 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 1.9 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.0 | 1.7 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.3 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 0.6 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
0.0 | 0.5 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 1.9 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 0.7 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 0.7 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 0.4 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.3 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.4 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 1.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.6 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.6 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.3 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.3 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.2 | PID_ENDOTHELIN_PATHWAY | Endothelins |
0.0 | 0.4 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.2 | PID_ARF_3PATHWAY | Arf1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
0.2 | 2.3 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.1 | 3.4 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 1.9 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 2.9 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.1 | 1.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.1 | 2.1 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.1 | 3.5 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.1 | 4.7 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.1 | 1.0 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.1 | 2.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 0.8 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.1 | 0.5 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.1 | 0.3 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.1 | 1.8 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.1 | 0.5 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.1 | 0.5 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
0.1 | 5.7 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.1 | 1.7 | REACTOME_CELL_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell-cell junction organization |
0.0 | 0.4 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.0 | 0.3 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.0 | 7.1 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 1.6 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.2 | REACTOME_NUCLEOTIDE_EXCISION_REPAIR | Genes involved in Nucleotide Excision Repair |
0.0 | 0.7 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | Genes involved in Post NMDA receptor activation events |
0.0 | 1.0 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.8 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 0.4 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.3 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 1.0 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.0 | 0.3 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.0 | 0.7 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 0.3 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.0 | 0.3 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 1.1 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.6 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.2 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.0 | 0.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.3 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.4 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 0.3 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.0 | 0.7 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 0.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.3 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.1 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.0 | 0.5 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.3 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.4 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |