Motif ID: Tcf3

Z-value: 0.960


Transcription factors associated with Tcf3:

Gene SymbolEntrez IDGene Name
Tcf3 ENSMUSG00000020167.8 Tcf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf3mm10_v2_chr10_-_80433615_804336550.672.3e-03Click!


Activity profile for motif Tcf3.

activity profile for motif Tcf3


Sorted Z-values histogram for motif Tcf3

Sorted Z-values for motif Tcf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_28302238 3.751 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr1_+_74791516 3.120 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr14_-_20181773 2.877 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr12_+_109459843 2.695 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr15_+_34238026 2.643 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_+_121707189 2.451 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr19_+_25610533 2.279 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr6_+_17307272 2.262 ENSMUST00000115454.1
Cav1
caveolin 1, caveolae protein
chr6_+_17307632 2.246 ENSMUST00000115453.1
Cav1
caveolin 1, caveolae protein
chr6_-_72235559 2.229 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr13_-_116309639 1.989 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr6_+_29694204 1.985 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr1_+_129273344 1.976 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr7_-_17056669 1.838 ENSMUST00000037762.4
Hif3a
hypoxia inducible factor 3, alpha subunit
chr17_-_35703971 1.827 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr12_+_110279228 1.789 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr5_-_98566762 1.787 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr8_-_122699066 1.784 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr13_-_60177357 1.773 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr7_+_19094594 1.757 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr4_+_45184815 1.743 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr14_+_27039001 1.555 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr5_-_135251209 1.547 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr17_-_35704000 1.542 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chrX_-_106485214 1.517 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr2_+_131186942 1.430 ENSMUST00000028804.8
ENSMUST00000079857.8
Cdc25b

cell division cycle 25B

chrX_-_133688978 1.419 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr1_-_119053339 1.349 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr3_-_32365608 1.330 ENSMUST00000168566.1
Zmat3
zinc finger matrin type 3
chr17_+_75178797 1.302 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr8_+_105518736 1.281 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr3_-_32365643 1.270 ENSMUST00000029199.5
Zmat3
zinc finger matrin type 3
chr15_-_98004695 1.266 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr6_+_47244359 1.252 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr15_-_98004634 1.252 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr6_+_56017489 1.249 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr1_-_183147461 1.244 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr10_-_7212222 1.239 ENSMUST00000015346.5
Cnksr3
Cnksr family member 3
chr3_-_116253467 1.238 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr11_-_82871133 1.196 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr19_-_15924560 1.159 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr3_+_95588990 1.150 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr18_+_57142782 1.150 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr8_-_61902669 1.149 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr4_-_133872997 1.137 ENSMUST00000137486.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr17_+_75178911 1.133 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr1_+_92831614 1.116 ENSMUST00000045970.6
Gpc1
glypican 1
chr2_+_14873656 1.105 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr7_-_25250720 1.103 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr11_+_117809653 1.103 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr6_-_3494587 1.072 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr1_+_187997835 1.071 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr3_+_125404292 1.056 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_+_62703667 1.050 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
Nrp2



neuropilin 2



chr9_+_102720287 1.035 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chrX_-_106485367 1.021 ENSMUST00000140707.1
Fndc3c1
fibronectin type III domain containing 3C1
chr12_+_51593315 1.018 ENSMUST00000164782.2
ENSMUST00000085412.5
Coch

coagulation factor C homolog (Limulus polyphemus)

chr19_+_53140430 1.018 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr1_+_187997821 1.008 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr9_+_35423582 1.004 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chrX_-_48034842 0.991 ENSMUST00000039026.7
Apln
apelin
chr5_-_114690906 0.990 ENSMUST00000112212.1
ENSMUST00000112214.1
Gltp

glycolipid transfer protein

chr7_+_107370728 0.990 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr8_+_95352258 0.984 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr19_-_45560508 0.979 ENSMUST00000026239.6
Poll
polymerase (DNA directed), lambda
chr11_-_95514570 0.974 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr1_+_62703285 0.974 ENSMUST00000102822.2
ENSMUST00000075144.5
Nrp2

neuropilin 2

chr18_+_57133065 0.970 ENSMUST00000075770.6
Megf10
multiple EGF-like-domains 10
chr8_+_45885479 0.967 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr19_+_56548254 0.962 ENSMUST00000071423.5
Nhlrc2
NHL repeat containing 2
chr2_-_73214323 0.962 ENSMUST00000100015.4
Ola1
Obg-like ATPase 1
chr1_+_153665666 0.927 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr3_-_144570136 0.920 ENSMUST00000043325.7
Hs2st1
heparan sulfate 2-O-sulfotransferase 1
chr18_+_60963517 0.915 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr3_+_125404072 0.910 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr2_-_73214409 0.908 ENSMUST00000028517.6
Ola1
Obg-like ATPase 1
chr11_-_101466222 0.881 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr1_+_153665274 0.861 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr15_-_78773452 0.861 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_117809687 0.857 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr3_+_95588960 0.853 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr1_-_119053619 0.851 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr4_+_137862237 0.849 ENSMUST00000102518.3
Ece1
endothelin converting enzyme 1
chr5_-_114690974 0.844 ENSMUST00000012028.7
Gltp
glycolipid transfer protein
chr2_-_33431324 0.839 ENSMUST00000113158.1
Zbtb34
zinc finger and BTB domain containing 34
chr7_+_45216671 0.821 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr3_+_95588928 0.814 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr3_+_146404978 0.813 ENSMUST00000129978.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chrX_-_48208870 0.807 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr9_+_120929216 0.792 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr4_+_41903610 0.791 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr2_+_27079371 0.782 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr5_+_64160207 0.779 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr1_+_72824482 0.774 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr15_+_72913357 0.774 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chr4_-_21685782 0.774 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr1_+_153665627 0.766 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr1_-_75219245 0.751 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr1_+_153665587 0.751 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr17_-_87797994 0.750 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr2_-_120539852 0.746 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr11_-_3527916 0.743 ENSMUST00000020718.4
Smtn
smoothelin
chr5_-_151651216 0.740 ENSMUST00000038131.9
Rfc3
replication factor C (activator 1) 3
chr9_+_102718424 0.723 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr9_-_21852603 0.720 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr2_-_80129458 0.718 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr11_-_94474088 0.717 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr8_+_94977101 0.704 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr2_-_64097994 0.701 ENSMUST00000131615.2
Fign
fidgetin
chr15_-_85578070 0.696 ENSMUST00000109424.2
Wnt7b
wingless-related MMTV integration site 7B
chr3_-_19264959 0.693 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr12_+_108334341 0.684 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr2_+_174760619 0.684 ENSMUST00000029030.2
Edn3
endothelin 3
chr8_+_36094828 0.682 ENSMUST00000110492.1
D8Ertd82e
DNA segment, Chr 8, ERATO Doi 82, expressed
chr17_+_84511832 0.680 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr4_-_133967296 0.672 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_117266216 0.671 ENSMUST00000019038.8
Sept9
septin 9
chr11_-_94242701 0.671 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr4_-_42168603 0.670 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr12_-_91779129 0.668 ENSMUST00000170077.1
Ston2
stonin 2
chrX_-_48208566 0.659 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr9_-_67760208 0.659 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr4_+_32983417 0.654 ENSMUST00000084747.5
Rragd
Ras-related GTP binding D
chr4_-_43523746 0.653 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chrX_-_72656135 0.650 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr6_-_124840192 0.645 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chr6_+_82402475 0.645 ENSMUST00000032122.8
Tacr1
tachykinin receptor 1
chr19_-_28680077 0.643 ENSMUST00000162022.1
ENSMUST00000112612.2
Glis3

GLIS family zinc finger 3

chr8_-_71511762 0.640 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr4_-_129696579 0.638 ENSMUST00000137640.1
Tmem39b
transmembrane protein 39b
chr6_-_53820764 0.636 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr2_+_34772089 0.635 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr4_-_131967824 0.631 ENSMUST00000146443.1
ENSMUST00000135579.1
Epb4.1

erythrocyte protein band 4.1

chr4_+_33031527 0.630 ENSMUST00000029944.6
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr6_-_31563978 0.629 ENSMUST00000026698.7
Podxl
podocalyxin-like
chr1_+_61638819 0.629 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr17_-_35702297 0.626 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr11_+_3202908 0.623 ENSMUST00000179770.1
ENSMUST00000110048.1
Eif4enif1

eukaryotic translation initiation factor 4E nuclear import factor 1

chr8_+_53511695 0.618 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr11_+_3202684 0.614 ENSMUST00000125637.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr4_+_152008803 0.611 ENSMUST00000097773.3
Klhl21
kelch-like 21
chr10_+_127063527 0.609 ENSMUST00000006911.5
Cdk4
cyclin-dependent kinase 4
chr2_-_30474199 0.608 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr17_-_48432723 0.604 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_-_28840274 0.599 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4

general transcription factor IIIC, polypeptide 4

chrX_+_151522352 0.596 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chr11_+_83964419 0.595 ENSMUST00000049714.8
ENSMUST00000092834.5
ENSMUST00000183714.1
ENSMUST00000183456.1
Synrg



synergin, gamma



chr2_+_103969528 0.594 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2

LIM domain only 2

chr7_+_127876796 0.594 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chr14_-_122451109 0.592 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr1_+_131970589 0.591 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr9_+_58134535 0.590 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr19_-_60581013 0.588 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1


CDK2 associated, cullin domain 1


chr17_-_32388885 0.586 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr2_-_163750169 0.578 ENSMUST00000017841.3
Ada
adenosine deaminase
chr4_+_137862270 0.573 ENSMUST00000130407.1
Ece1
endothelin converting enzyme 1
chr15_-_103215285 0.573 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr10_+_127063599 0.571 ENSMUST00000120226.1
ENSMUST00000133115.1
Cdk4

cyclin-dependent kinase 4

chr4_-_43523388 0.570 ENSMUST00000107913.3
ENSMUST00000030184.5
Tpm2

tropomyosin 2, beta

chr1_-_171234290 0.568 ENSMUST00000079957.6
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr17_+_28142267 0.566 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3
chr18_-_61707583 0.564 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr4_+_33031371 0.561 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr2_+_5137756 0.559 ENSMUST00000027988.7
Ccdc3
coiled-coil domain containing 3
chr16_+_38902305 0.557 ENSMUST00000023478.7
Igsf11
immunoglobulin superfamily, member 11
chr4_-_135272798 0.556 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr2_+_119112793 0.555 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr14_+_70457447 0.554 ENSMUST00000003561.3
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr4_+_128883549 0.554 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr1_+_109993982 0.535 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr3_-_73708399 0.534 ENSMUST00000029367.5
Bche
butyrylcholinesterase
chr13_-_98890974 0.528 ENSMUST00000179301.1
ENSMUST00000179271.1
Tnpo1

transportin 1

chr5_-_21701332 0.528 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr4_-_133967235 0.524 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr5_+_123142187 0.522 ENSMUST00000174836.1
ENSMUST00000163030.2
Setd1b

SET domain containing 1B

chr9_-_39604124 0.521 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr17_-_35700520 0.520 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr8_-_40634750 0.517 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr2_-_103485138 0.516 ENSMUST00000028610.3
Cat
catalase
chr9_-_108263887 0.515 ENSMUST00000166905.1
ENSMUST00000080435.2
Dag1

dystroglycan 1

chr19_+_5068077 0.513 ENSMUST00000070630.6
Cd248
CD248 antigen, endosialin
chr17_+_28691419 0.509 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr3_-_100489324 0.506 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr11_-_84916338 0.503 ENSMUST00000103195.4
Znhit3
zinc finger, HIT type 3
chr6_-_83441674 0.502 ENSMUST00000089622.4
Tet3
tet methylcytosine dioxygenase 3
chr11_+_32455362 0.495 ENSMUST00000051053.4
Ubtd2
ubiquitin domain containing 2
chr5_-_98030727 0.494 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr5_-_52566264 0.494 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr2_-_103485068 0.492 ENSMUST00000111168.3
Cat
catalase
chr13_+_51846673 0.489 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr6_+_88724828 0.489 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr13_+_23751069 0.489 ENSMUST00000078369.1
Hist1h2ab
histone cluster 1, H2ab
chr4_-_133872304 0.487 ENSMUST00000157067.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr5_-_149053038 0.487 ENSMUST00000085546.6
Hmgb1
high mobility group box 1
chr13_+_23544052 0.482 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr19_-_4928241 0.477 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr7_-_101837776 0.473 ENSMUST00000165052.1
Inppl1
inositol polyphosphate phosphatase-like 1
chr2_-_18048784 0.470 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr14_-_30607808 0.465 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
Prkcd



protein kinase C, delta



chr19_+_46623387 0.465 ENSMUST00000111855.4
Wbp1l
WW domain binding protein 1 like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.8 3.8 GO:0007386 compartment pattern specification(GO:0007386)
0.7 2.0 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.7 2.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.5 2.2 GO:0060032 notochord regression(GO:0060032)
0.5 1.5 GO:1990523 bone regeneration(GO:1990523)
0.5 5.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.5 1.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.4 1.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 3.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.4 1.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 1.5 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.4 1.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 1.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 3.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.4 4.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 1.0 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.3 1.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 1.2 GO:0061743 motor learning(GO:0061743)
0.3 2.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 1.2 GO:0010288 response to lead ion(GO:0010288)
0.3 0.6 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.3 0.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 1.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.3 1.8 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.3 1.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 3.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 1.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.9 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.2 0.9 GO:0030202 heparin metabolic process(GO:0030202)
0.2 0.7 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.2 1.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 0.9 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 1.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 1.4 GO:0007144 female meiosis I(GO:0007144)
0.2 1.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.6 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 0.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 0.6 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) serotonin secretion by platelet(GO:0002554)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 2.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 2.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.6 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.2 0.7 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 0.5 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 1.8 GO:0060539 diaphragm development(GO:0060539)
0.2 1.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 0.5 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.2 1.8 GO:0014841 skeletal muscle satellite cell proliferation(GO:0014841)
0.1 0.4 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.1 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0051593 response to folic acid(GO:0051593)
0.1 1.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.2 GO:0042534 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.1 0.5 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 2.7 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 1.3 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.1 2.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 2.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.3 GO:2000850 protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 1.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.7 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.2 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.1 0.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.4 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.5 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.6 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 1.0 GO:0009650 UV protection(GO:0009650)
0.1 0.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.6 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0006868 glutamine transport(GO:0006868)
0.1 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.5 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.1 0.4 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.8 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 1.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.4 GO:0032439 endosome localization(GO:0032439)
0.1 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 2.6 GO:0035329 hippo signaling(GO:0035329)
0.1 0.5 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 0.8 GO:0060482 lobar bronchus development(GO:0060482)
0.1 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.3 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.2 GO:0006706 steroid catabolic process(GO:0006706)
0.1 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.3 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.9 GO:0042493 response to drug(GO:0042493)
0.0 0.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.5 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.5 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.9 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.0 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.3 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.3 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 1.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.7 GO:2000573 positive regulation of DNA biosynthetic process(GO:2000573)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.4 GO:0000154 rRNA modification(GO:0000154)
0.0 0.2 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.4 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.4 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 1.0 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 0.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.3 4.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 0.9 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.3 1.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 0.8 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.2 2.2 GO:0097542 ciliary tip(GO:0097542)
0.2 0.9 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0043209 myelin sheath(GO:0043209)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0001940 male pronucleus(GO:0001940)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 1.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.6 GO:0031090 organelle membrane(GO:0031090)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.6 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 1.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 4.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 3.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0099568 cell cortex(GO:0005938) cytoplasmic region(GO:0099568)
0.0 4.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005901 caveola(GO:0005901)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 1.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 2.4 GO:0005819 spindle(GO:0005819)
0.0 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0043235 receptor complex(GO:0043235)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.6 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.8 3.2 GO:0050436 microfibril binding(GO:0050436)
0.5 1.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 2.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 4.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 1.1 GO:0070052 collagen V binding(GO:0070052)
0.4 1.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 2.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 3.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.3 2.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 0.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.0 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.2 0.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 4.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1 1.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 3.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.8 GO:0051861 glycolipid binding(GO:0051861)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 3.6 GO:0005109 frizzled binding(GO:0005109)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.7 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 2.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 3.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.2 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.9 GO:0070888 E-box binding(GO:0070888)
0.1 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 4.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.1 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.0 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0015108 chloride transmembrane transporter activity(GO:0015108)
0.0 0.6 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.2 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 4.7 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.2 5.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.9 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 1.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.5 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.0 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 0.9 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.2 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.6 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 3.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.1 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.6 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 3.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.2 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.6 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.9 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.6 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.1 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.1 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.4 REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.2 2.0 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.7 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 3.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 4.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.4 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.5 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 2.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 2.7 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.1 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.5 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.6 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 0.9 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.6 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 1.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 3.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 3.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.2 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_IL_3_5_AND_GM_CSF_SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.7 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.6 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 1.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME_IL_2_SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis