Motif ID: Gsc2_Dmbx1
Z-value: 0.501


Transcription factors associated with Gsc2_Dmbx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dmbx1 | ENSMUSG00000028707.9 | Dmbx1 |
Gsc2 | ENSMUSG00000022738.6 | Gsc2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dmbx1 | mm10_v2_chr4_-_115939923_115939928 | 0.17 | 4.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.3 | GO:0032053 | ciliary basal body organization(GO:0032053) |
0.3 | 0.8 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913) |
0.3 | 1.5 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
0.2 | 0.9 | GO:2000705 | regulation of dense core granule biogenesis(GO:2000705) |
0.2 | 0.5 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
0.2 | 1.0 | GO:0086028 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
0.2 | 0.6 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
0.1 | 0.4 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.1 | 0.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.1 | 0.5 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.1 | 0.4 | GO:0030576 | Cajal body organization(GO:0030576) |
0.1 | 0.3 | GO:0016056 | photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
0.1 | 0.9 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 0.5 | GO:0002681 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
0.1 | 2.1 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 1.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:0015747 | urate transport(GO:0015747) |
0.0 | 0.3 | GO:0032782 | bile acid secretion(GO:0032782) |
0.0 | 0.1 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.0 | 0.1 | GO:1902524 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
0.0 | 0.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.0 | 0.1 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.0 | 0.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.0 | 0.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.1 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.0 | 0.3 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.2 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.0 | 0.1 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.0 | 0.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.3 | GO:0055070 | copper ion homeostasis(GO:0055070) |
0.0 | 0.0 | GO:0045358 | negative regulation of interferon-beta biosynthetic process(GO:0045358) |
0.0 | 1.0 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.4 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
0.0 | 0.3 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.1 | 2.3 | GO:0005652 | nuclear lamina(GO:0005652) |
0.1 | 2.1 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
0.1 | 1.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 1.5 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.7 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.9 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 1.5 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.3 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.0 | 0.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.2 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.3 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.5 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 1.0 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 0.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.3 | 1.3 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
0.1 | 0.4 | GO:0070140 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
0.1 | 0.5 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
0.1 | 1.5 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.1 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.9 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.1 | 0.5 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 0.3 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.1 | 0.9 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.1 | 0.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.1 | 0.4 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.5 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.1 | 0.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.1 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 1.0 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.4 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
0.0 | 0.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 0.5 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 1.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 1.1 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.3 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.0 | 0.1 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.6 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 0.8 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 0.1 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 1.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.1 | REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION | Genes involved in Incretin Synthesis, Secretion, and Inactivation |
0.0 | 0.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 1.5 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.1 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.0 | 1.0 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 0.5 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 0.1 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |