Motif ID: Hoxb1
Z-value: 0.747

Transcription factors associated with Hoxb1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxb1 | ENSMUSG00000018973.2 | Hoxb1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 7.0 | GO:0060032 | notochord regression(GO:0060032) |
0.4 | 1.6 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
0.4 | 1.1 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.3 | 0.3 | GO:0072038 | mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038) |
0.3 | 3.5 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
0.3 | 0.9 | GO:0072092 | ureteric bud invasion(GO:0072092) |
0.3 | 0.8 | GO:1990927 | negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927) |
0.2 | 1.1 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
0.1 | 1.0 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.1 | 0.3 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
0.1 | 1.4 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
0.1 | 0.8 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 0.5 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.1 | 0.9 | GO:2001054 | negative regulation of mesenchymal cell apoptotic process(GO:2001054) |
0.1 | 0.3 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.1 | 0.4 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.1 | 1.0 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.1 | 0.4 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
0.1 | 0.2 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) negative regulation of apoptotic process involved in morphogenesis(GO:1902338) negative regulation of apoptotic process involved in development(GO:1904746) |
0.1 | 0.6 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.3 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
0.0 | 1.4 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.0 | 1.2 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.0 | 0.4 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.0 | 0.3 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 1.0 | GO:0006826 | iron ion transport(GO:0006826) |
0.0 | 1.3 | GO:0007628 | adult walking behavior(GO:0007628) |
0.0 | 0.6 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.0 | 2.2 | GO:0021954 | central nervous system neuron development(GO:0021954) |
0.0 | 0.5 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.0 | 0.2 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 1.5 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.0 | 0.9 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 7.0 | GO:0097542 | ciliary tip(GO:0097542) |
0.4 | 1.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 0.5 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.1 | 0.8 | GO:0032009 | early phagosome(GO:0032009) |
0.1 | 0.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.0 | 1.0 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 1.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 3.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.1 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.0 | 0.2 | GO:0005858 | axonemal dynein complex(GO:0005858) |
0.0 | 0.9 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.7 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.3 | 0.9 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
0.3 | 1.5 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.3 | 3.5 | GO:1990459 | transferrin receptor binding(GO:1990459) |
0.2 | 0.6 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.2 | 6.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 1.1 | GO:0048495 | Roundabout binding(GO:0048495) |
0.1 | 0.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.1 | 1.0 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.1 | 0.3 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.1 | 0.9 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 2.2 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.4 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.0 | 1.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.3 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 1.2 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.8 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 1.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 1.0 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.2 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 7.0 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 3.5 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.4 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 1.1 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.8 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 1.1 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.6 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.1 | 1.5 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 1.2 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.5 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.5 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.1 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.6 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |