Motif ID: Pou3f2
Z-value: 0.539

Transcription factors associated with Pou3f2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou3f2 | ENSMUSG00000095139.1 | Pou3f2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou3f2 | mm10_v2_chr4_-_22488296_22488366 | 0.46 | 5.6e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
0.3 | 1.3 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.2 | 2.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.2 | 2.0 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.2 | 1.0 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
0.1 | 0.6 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.1 | 1.0 | GO:0002674 | negative regulation of acute inflammatory response(GO:0002674) |
0.1 | 0.8 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 0.5 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
0.1 | 0.5 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 0.5 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
0.1 | 0.9 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 0.5 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
0.1 | 0.7 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.1 | 0.6 | GO:0032439 | endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549) |
0.1 | 0.7 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.1 | 1.2 | GO:0015809 | arginine transport(GO:0015809) |
0.1 | 0.3 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.1 | 0.3 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.1 | 1.3 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.1 | 0.4 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.1 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.1 | 0.9 | GO:0072112 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
0.0 | 0.3 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
0.0 | 0.8 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.2 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.0 | 0.6 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.5 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.0 | 0.7 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.3 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.0 | 0.3 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.2 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
0.0 | 0.5 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.3 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
0.0 | 0.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.0 | 0.1 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 0.1 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.6 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.3 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
0.0 | 0.5 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
0.0 | 0.1 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.0 | 1.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.2 | GO:0070842 | aggresome assembly(GO:0070842) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0031673 | H zone(GO:0031673) |
0.1 | 1.0 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 1.3 | GO:0044754 | autolysosome(GO:0044754) |
0.1 | 0.9 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 0.6 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.1 | 0.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.0 | 0.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.8 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 0.4 | GO:0042581 | specific granule(GO:0042581) |
0.0 | 0.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 1.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.3 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.0 | 0.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.1 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 0.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.3 | 2.2 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
0.3 | 1.3 | GO:0043532 | angiostatin binding(GO:0043532) |
0.2 | 0.5 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.2 | 1.0 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.2 | 0.5 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.2 | 1.2 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.1 | 0.6 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 0.5 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.1 | 0.7 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.1 | 0.9 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 0.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.3 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.1 | 0.4 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.1 | 0.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.0 | 0.1 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.0 | 2.0 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.5 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.0 | 0.5 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.3 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.0 | 0.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.2 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.1 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.1 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.9 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.0 | 2.8 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.0 | 0.5 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 1.8 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.8 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 0.7 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 0.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.8 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.3 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 1.5 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
0.0 | 0.2 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.0 | 1.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.5 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.0 | 0.8 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 1.4 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.1 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.0 | 0.2 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 0.7 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |