Motif ID: Gli2

Z-value: 0.547


Transcription factors associated with Gli2:

Gene SymbolEntrez IDGene Name
Gli2 ENSMUSG00000048402.8 Gli2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli2mm10_v2_chr1_-_119053619_1190536380.401.0e-01Click!


Activity profile for motif Gli2.

activity profile for motif Gli2


Sorted Z-values histogram for motif Gli2

Sorted Z-values for motif Gli2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gli2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_72789240 2.244 ENSMUST00000069536.5
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr6_-_72788952 2.193 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr6_-_23248264 1.634 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr5_-_24527276 1.322 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr7_-_4752972 1.237 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr7_-_137314394 0.983 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr9_-_43239816 0.969 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chrX_-_141725181 0.948 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr8_+_127064022 0.942 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr3_-_135608221 0.928 ENSMUST00000132668.1
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr7_-_144738520 0.914 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr4_+_124700700 0.874 ENSMUST00000106199.3
ENSMUST00000038684.5
Fhl3

four and a half LIM domains 3

chr8_+_127063893 0.840 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr7_-_116308241 0.834 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
Plekha7


pleckstrin homology domain containing, family A member 7


chr7_-_144738478 0.774 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chr13_+_35741313 0.682 ENSMUST00000163595.2
Cdyl
chromodomain protein, Y chromosome-like
chr8_+_127064107 0.638 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr9_+_62342449 0.615 ENSMUST00000156461.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_+_121039385 0.606 ENSMUST00000030372.5
Col9a2
collagen, type IX, alpha 2
chr6_+_120666388 0.520 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr3_+_127633134 0.514 ENSMUST00000029587.7
Neurog2
neurogenin 2
chrX_-_9662950 0.511 ENSMUST00000033519.2
Dynlt3
dynein light chain Tctex-type 3
chr4_+_63215402 0.505 ENSMUST00000036300.6
Col27a1
collagen, type XXVII, alpha 1
chr16_-_17132377 0.502 ENSMUST00000023453.7
Sdf2l1
stromal cell-derived factor 2-like 1
chr5_+_117319258 0.501 ENSMUST00000111967.1
Vsig10
V-set and immunoglobulin domain containing 10
chr4_-_83486453 0.478 ENSMUST00000107214.2
ENSMUST00000107215.2
ENSMUST00000030207.8
Psip1


PC4 and SFRS1 interacting protein 1


chr19_+_6975048 0.456 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_+_137049586 0.438 ENSMUST00000047852.7
Fam199x
family with sequence similarity 199, X-linked
chr5_+_117319292 0.427 ENSMUST00000086464.4
Vsig10
V-set and immunoglobulin domain containing 10
chr14_+_64950037 0.419 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr7_-_133123312 0.408 ENSMUST00000124096.1
ENSMUST00000171022.1
ENSMUST00000163601.1
ENSMUST00000165534.1
ENSMUST00000033269.8
Fgfr2
Ctbp2



fibroblast growth factor receptor 2
C-terminal binding protein 2



chr2_+_164486455 0.406 ENSMUST00000069385.8
ENSMUST00000143690.1
Dbndd2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr17_+_47594629 0.388 ENSMUST00000182846.1
Ccnd3
cyclin D3
chr17_-_31658729 0.386 ENSMUST00000166526.1
ENSMUST00000014684.4
U2af1

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1

chrX_-_167382747 0.377 ENSMUST00000026839.4
Prps2
phosphoribosyl pyrophosphate synthetase 2
chr4_-_83486178 0.364 ENSMUST00000130626.1
Psip1
PC4 and SFRS1 interacting protein 1
chr7_-_133123160 0.363 ENSMUST00000166439.1
Ctbp2
C-terminal binding protein 2
chr19_+_6047081 0.363 ENSMUST00000025723.8
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr19_+_6047055 0.361 ENSMUST00000134667.1
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr4_+_32800246 0.354 ENSMUST00000062802.4
Lyrm2
LYR motif containing 2
chr15_+_95790831 0.333 ENSMUST00000071874.6
Ano6
anoctamin 6
chr3_+_36552600 0.329 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chr15_-_56694525 0.325 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr8_-_67515606 0.320 ENSMUST00000032981.5
Gm9755
predicted pseudogene 9755
chr6_+_43265582 0.320 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr15_-_85581809 0.318 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chrX_+_100730178 0.306 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr5_+_23850590 0.300 ENSMUST00000181574.1
2700038G22Rik
RIKEN cDNA 2700038G22 gene
chr7_+_35119285 0.297 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_100620165 0.295 ENSMUST00000014339.8
Dnajc7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr11_+_101176041 0.295 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chrX_+_20617503 0.294 ENSMUST00000115375.1
ENSMUST00000115374.1
ENSMUST00000084383.3
Rbm10


RNA binding motif protein 10


chr11_+_51619731 0.293 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr5_-_115300912 0.292 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr5_-_115300957 0.292 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr13_+_55445301 0.280 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6

G protein-coupled receptor kinase 6

chr17_+_24632671 0.278 ENSMUST00000047611.2
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr4_-_59783800 0.277 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr5_-_137786681 0.264 ENSMUST00000132726.1
Mepce
methylphosphate capping enzyme
chr1_-_175625580 0.263 ENSMUST00000027810.7
Fh1
fumarate hydratase 1
chr11_+_117308135 0.261 ENSMUST00000153668.1
Sept9
septin 9
chrX_+_100729917 0.255 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr4_-_135971894 0.255 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr4_-_126256226 0.253 ENSMUST00000122129.1
ENSMUST00000061143.8
ENSMUST00000106132.2
Map7d1


MAP7 domain containing 1


chr10_-_93589621 0.251 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr10_-_99126321 0.233 ENSMUST00000060761.5
Phxr2
per-hexamer repeat gene 2
chr9_+_55149364 0.233 ENSMUST00000121677.1
Ube2q2
ubiquitin-conjugating enzyme E2Q (putative) 2
chr5_-_137786651 0.230 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr4_-_121098190 0.223 ENSMUST00000058754.2
Zmpste24
zinc metallopeptidase, STE24
chr2_+_69861562 0.216 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr9_+_13662460 0.210 ENSMUST00000177755.1
Maml2
mastermind like 2 (Drosophila)
chr6_+_67266979 0.208 ENSMUST00000042990.4
Serbp1
serpine1 mRNA binding protein 1
chr17_-_84187939 0.206 ENSMUST00000060366.6
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr5_-_117319242 0.201 ENSMUST00000100834.1
Gm10399
predicted gene 10399
chr17_+_28691342 0.199 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14



chr9_-_69760924 0.198 ENSMUST00000071281.4
Foxb1
forkhead box B1
chr7_-_133122615 0.195 ENSMUST00000167218.1
Ctbp2
C-terminal binding protein 2
chr1_-_51915968 0.184 ENSMUST00000046390.7
Myo1b
myosin IB
chr7_-_65371210 0.183 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr2_+_69861638 0.179 ENSMUST00000112260.1
Ssb
Sjogren syndrome antigen B
chr10_+_80151154 0.179 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr18_-_35662180 0.178 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr13_+_44730726 0.178 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr10_+_93589413 0.169 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr5_-_53213447 0.164 ENSMUST00000031090.6
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_+_45055166 0.159 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr19_+_6057888 0.157 ENSMUST00000043074.5
ENSMUST00000178310.1
Fau

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

chr4_-_126321669 0.150 ENSMUST00000102617.4
Adprhl2
ADP-ribosylhydrolase like 2
chr7_-_81454751 0.149 ENSMUST00000098331.3
ENSMUST00000178892.1
Cpeb1

cytoplasmic polyadenylation element binding protein 1

chr9_+_114401076 0.146 ENSMUST00000063042.9
ENSMUST00000111820.2
Glb1
Tmppe
galactosidase, beta 1
transmembrane protein with metallophosphoesterase domain
chr10_+_42502030 0.143 ENSMUST00000105500.1
ENSMUST00000019939.5
Snx3

sorting nexin 3

chr7_-_133123409 0.139 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr1_-_51915901 0.138 ENSMUST00000018561.7
ENSMUST00000114537.2
Myo1b

myosin IB

chr16_-_4077778 0.136 ENSMUST00000006137.8
Trap1
TNF receptor-associated protein 1
chr16_-_88056176 0.131 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chr17_+_28691419 0.128 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr4_+_117096049 0.127 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr2_+_120609383 0.124 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr1_+_167349976 0.122 ENSMUST00000028004.9
Aldh9a1
aldehyde dehydrogenase 9, subfamily A1
chr16_+_19760902 0.119 ENSMUST00000119468.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr4_+_36952930 0.115 ENSMUST00000144029.1
Gm12371
predicted gene 12371
chr7_-_121035096 0.113 ENSMUST00000065740.2
Gm9905
predicted gene 9905
chr9_+_109095427 0.110 ENSMUST00000072093.6
Plxnb1
plexin B1
chr2_-_37703275 0.108 ENSMUST00000072186.5
Strbp
spermatid perinuclear RNA binding protein
chr17_+_24669730 0.105 ENSMUST00000047179.5
Zfp598
zinc finger protein 598
chr18_-_38250157 0.101 ENSMUST00000181871.1
1700086O06Rik
RIKEN cDNA 1700086O06 gene
chr15_+_41447438 0.100 ENSMUST00000110297.2
ENSMUST00000090096.4
Oxr1

oxidation resistance 1

chr5_-_134456227 0.100 ENSMUST00000111244.1
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr4_+_155831272 0.100 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr7_+_121707189 0.091 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr3_-_95357156 0.087 ENSMUST00000107171.3
ENSMUST00000015841.5
ENSMUST00000107170.2
Setdb1


SET domain, bifurcated 1


chr11_+_100619217 0.085 ENSMUST00000107376.1
Nkiras2
NFKB inhibitor interacting Ras-like protein 2
chr15_-_77970750 0.085 ENSMUST00000100484.4
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr1_-_153332724 0.085 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr4_+_155831630 0.082 ENSMUST00000105592.1
ENSMUST00000105591.1
Aurkaip1

aurora kinase A interacting protein 1

chr1_+_97770158 0.081 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chr11_-_100619576 0.080 ENSMUST00000155152.1
Dnajc7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr2_-_120609319 0.077 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr2_+_49451486 0.075 ENSMUST00000092123.4
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr11_-_118909487 0.074 ENSMUST00000117731.1
ENSMUST00000106278.2
ENSMUST00000120061.1
ENSMUST00000017576.4
Rbfox3



RNA binding protein, fox-1 homolog (C. elegans) 3



chr7_+_81571246 0.065 ENSMUST00000165460.1
Whamm
WAS protein homolog associated with actin, golgi membranes and microtubules
chr2_-_120609283 0.063 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr15_+_78899755 0.062 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
Sh3bp1


SH3-domain binding protein 1


chr9_+_114978507 0.056 ENSMUST00000183104.1
Osbpl10
oxysterol binding protein-like 10
chr1_+_71652837 0.053 ENSMUST00000097699.2
Apol7d
apolipoprotein L 7d
chr4_-_154899077 0.050 ENSMUST00000030935.3
ENSMUST00000132281.1
Fam213b

family with sequence similarity 213, member B

chr4_-_126968124 0.047 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chr11_+_32455362 0.043 ENSMUST00000051053.4
Ubtd2
ubiquitin domain containing 2
chr18_+_80206775 0.035 ENSMUST00000125127.1
ENSMUST00000025463.7
ENSMUST00000145963.1
ENSMUST00000025464.7
Gm16286

Txnl4a

predicted gene 16286

thioredoxin-like 4A

chr4_-_19708922 0.034 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr2_-_120609500 0.034 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr8_-_13890233 0.033 ENSMUST00000033839.7
Coprs
coordinator of PRMT5, differentiation stimulator
chr18_+_80206887 0.032 ENSMUST00000127234.1
Gm16286
predicted gene 16286
chr3_+_9250602 0.029 ENSMUST00000155203.1
Zbtb10
zinc finger and BTB domain containing 10
chr3_+_28781305 0.027 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr12_-_31950170 0.025 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr17_-_56609689 0.023 ENSMUST00000052832.5
2410015M20Rik
RIKEN cDNA 2410015M20 gene
chr9_-_108578657 0.018 ENSMUST00000068700.5
Wdr6
WD repeat domain 6
chr16_-_20302358 0.007 ENSMUST00000048642.8
Parl
presenilin associated, rhomboid-like
chr14_-_64949838 0.006 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
Hmbox1





homeobox containing 1





chr8_-_27174623 0.003 ENSMUST00000033878.6
ENSMUST00000054212.6
Rab11fip1

RAB11 family interacting protein 1 (class I)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.4 2.4 GO:0003383 apical constriction(GO:0003383)
0.3 1.7 GO:0015705 iodide transport(GO:0015705)
0.3 1.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.3 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.1 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.8 GO:0040031 snRNA modification(GO:0040031)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.3 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.5 GO:0001842 neural fold formation(GO:0001842)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.3 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0033269 internode region of axon(GO:0033269)
0.2 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0090537 CERF complex(GO:0090537)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.8 GO:0005915 zonula adherens(GO:0005915)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.8 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.3 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 4.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.9 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 3.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway