Motif ID: Hand1
Z-value: 1.002

Transcription factors associated with Hand1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hand1 | ENSMUSG00000037335.7 | Hand1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.8 | 3.1 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.7 | 2.0 | GO:0071873 | response to norepinephrine(GO:0071873) |
0.5 | 2.7 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
0.5 | 1.5 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.4 | 1.2 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.4 | 1.2 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
0.4 | 2.2 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
0.4 | 1.1 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
0.4 | 1.8 | GO:0098735 | cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735) |
0.3 | 1.0 | GO:0007525 | somatic muscle development(GO:0007525) |
0.3 | 2.1 | GO:2001023 | regulation of response to drug(GO:2001023) |
0.3 | 1.7 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
0.3 | 2.1 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.3 | 0.8 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
0.2 | 2.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.2 | 1.2 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.2 | 0.6 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.2 | 2.0 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.2 | 0.5 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.2 | 0.5 | GO:0002030 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) |
0.2 | 0.7 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
0.2 | 1.1 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.2 | 1.4 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.2 | 1.4 | GO:0030035 | microspike assembly(GO:0030035) |
0.1 | 0.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.1 | 0.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.1 | 1.0 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 0.4 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.1 | 0.3 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
0.1 | 2.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.9 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
0.1 | 0.8 | GO:0021631 | optic nerve morphogenesis(GO:0021631) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188) |
0.1 | 0.7 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.1 | 0.6 | GO:0032489 | regulation of Cdc42 protein signal transduction(GO:0032489) |
0.1 | 0.4 | GO:0051715 | cytolysis in other organism(GO:0051715) |
0.1 | 0.6 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
0.1 | 0.4 | GO:1901608 | regulation of vesicle transport along microtubule(GO:1901608) |
0.1 | 0.3 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) |
0.1 | 0.3 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.1 | 0.4 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.1 | 0.3 | GO:0060023 | soft palate development(GO:0060023) |
0.1 | 0.4 | GO:1904996 | diapedesis(GO:0050904) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
0.1 | 0.5 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.1 | 0.8 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 1.3 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.1 | 1.2 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
0.1 | 1.6 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.1 | 0.3 | GO:0018094 | protein polyglycylation(GO:0018094) |
0.1 | 0.5 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.5 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
0.1 | 0.3 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
0.1 | 0.9 | GO:0048563 | post-embryonic organ morphogenesis(GO:0048563) |
0.1 | 0.7 | GO:0071569 | protein ufmylation(GO:0071569) |
0.1 | 0.6 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
0.1 | 0.6 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.1 | 1.0 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 0.8 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 1.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.1 | 0.7 | GO:0042989 | sequestering of actin monomers(GO:0042989) actin filament severing(GO:0051014) |
0.1 | 0.2 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.1 | 0.5 | GO:0033227 | dsRNA transport(GO:0033227) |
0.1 | 1.3 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.1 | 0.3 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.1 | 0.2 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
0.1 | 2.8 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.1 | 1.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 0.6 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
0.1 | 1.2 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.1 | 2.4 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
0.1 | 0.3 | GO:0032439 | endosome localization(GO:0032439) |
0.1 | 0.4 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 1.4 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.0 | 0.4 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.0 | 0.1 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.0 | 0.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.0 | 0.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.0 | 0.5 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.0 | 2.2 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
0.0 | 0.1 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
0.0 | 0.1 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) NMDA glutamate receptor clustering(GO:0097114) |
0.0 | 0.2 | GO:0044805 | late nucleophagy(GO:0044805) |
0.0 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.0 | 0.4 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
0.0 | 0.2 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.0 | 0.2 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.0 | 0.7 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
0.0 | 0.3 | GO:0031642 | negative regulation of myelination(GO:0031642) |
0.0 | 0.4 | GO:0003094 | glomerular filtration(GO:0003094) |
0.0 | 0.3 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 0.1 | GO:0061743 | motor learning(GO:0061743) |
0.0 | 0.2 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 0.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.0 | 0.5 | GO:0030575 | nuclear body organization(GO:0030575) |
0.0 | 0.8 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.0 | 0.3 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.0 | 0.2 | GO:0034227 | tRNA thio-modification(GO:0034227) |
0.0 | 0.7 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.0 | 0.8 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.0 | 0.1 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.0 | 0.4 | GO:0035881 | amacrine cell differentiation(GO:0035881) retinal rod cell development(GO:0046548) |
0.0 | 0.7 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 2.4 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 0.3 | GO:0036159 | outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159) |
0.0 | 0.2 | GO:0014029 | neural crest formation(GO:0014029) |
0.0 | 0.4 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
0.0 | 0.9 | GO:0043113 | receptor clustering(GO:0043113) |
0.0 | 0.9 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 3.0 | GO:0007416 | synapse assembly(GO:0007416) |
0.0 | 0.3 | GO:0006555 | methionine metabolic process(GO:0006555) |
0.0 | 0.1 | GO:0061734 | parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) |
0.0 | 0.0 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
0.0 | 0.5 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.1 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 0.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.4 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
0.0 | 1.5 | GO:0007613 | memory(GO:0007613) |
0.0 | 1.0 | GO:0046324 | regulation of glucose import(GO:0046324) |
0.0 | 0.3 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
0.0 | 0.5 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.4 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.4 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.9 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
0.0 | 0.2 | GO:0060444 | branching involved in mammary gland duct morphogenesis(GO:0060444) |
0.0 | 0.2 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
0.0 | 0.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.9 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 0.3 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
0.0 | 0.3 | GO:0009299 | mRNA transcription(GO:0009299) |
0.0 | 0.6 | GO:0006998 | nuclear envelope organization(GO:0006998) |
0.0 | 0.2 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
0.0 | 0.0 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
0.0 | 0.1 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0043512 | inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512) |
0.4 | 2.7 | GO:0044308 | axonal spine(GO:0044308) |
0.4 | 1.7 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
0.3 | 1.4 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.2 | 1.2 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.2 | 2.1 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 0.6 | GO:0097447 | dendritic tree(GO:0097447) |
0.1 | 0.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.1 | 0.4 | GO:0098855 | HCN channel complex(GO:0098855) |
0.1 | 2.0 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.1 | 2.0 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.1 | 2.1 | GO:1990635 | proximal dendrite(GO:1990635) |
0.1 | 0.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.1 | 0.5 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.1 | 1.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 0.4 | GO:0002139 | stereocilia coupling link(GO:0002139) |
0.1 | 0.5 | GO:0097443 | sorting endosome(GO:0097443) |
0.1 | 0.8 | GO:0032426 | stereocilium tip(GO:0032426) |
0.1 | 0.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 2.0 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.1 | 0.5 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.6 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.1 | 0.3 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 3.5 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.1 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.2 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 1.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.7 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 1.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 2.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.6 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.0 | 1.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 3.4 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.2 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 1.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.3 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.3 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 1.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 1.4 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.2 | GO:0089701 | U2AF(GO:0089701) |
0.0 | 0.4 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.4 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.1 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 1.5 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 0.2 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
0.0 | 0.4 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 0.3 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.3 | GO:0030904 | retromer complex(GO:0030904) |
0.0 | 1.8 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 2.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.1 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.5 | 2.0 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.4 | 1.8 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.4 | 2.0 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.4 | 2.4 | GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.4 | 1.1 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.4 | 2.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.3 | 2.2 | GO:0034711 | inhibin binding(GO:0034711) |
0.2 | 1.2 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.2 | 0.6 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.2 | 0.5 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
0.2 | 0.6 | GO:0042834 | peptidoglycan binding(GO:0042834) |
0.1 | 0.5 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.1 | 0.4 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 0.5 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.1 | 1.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 0.5 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
0.1 | 2.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.1 | 0.5 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.1 | 0.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 0.4 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.1 | 1.0 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.1 | 2.0 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 0.8 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 1.3 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 0.4 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.1 | 0.5 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.1 | 0.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.1 | 0.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.3 | GO:0070736 | protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) |
0.1 | 0.4 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.1 | 0.6 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.1 | 0.5 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 0.8 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.1 | 0.4 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.1 | 1.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.2 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.1 | 0.8 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.1 | 0.2 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.1 | 1.2 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
0.1 | 1.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 0.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 0.2 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.0 | 0.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.1 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.7 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.0 | 1.0 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.5 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 1.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 3.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 2.0 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 2.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 1.0 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.1 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
0.0 | 1.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.2 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.0 | 0.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.0 | 0.4 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.0 | 0.2 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 2.6 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.0 | 0.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.0 | 0.3 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.0 | 0.1 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
0.0 | 1.5 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.2 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.6 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.6 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.7 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.3 | GO:0016594 | glycine binding(GO:0016594) |
0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.8 | GO:0030145 | manganese ion binding(GO:0030145) |
0.0 | 0.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.2 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
0.0 | 0.2 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
0.0 | 2.1 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.2 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.0 | 0.3 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.0 | 0.2 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 0.0 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
0.0 | 0.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 2.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 0.3 | GO:0043022 | ribosome binding(GO:0043022) |
0.0 | 0.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.1 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.0 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.2 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.1 | 1.5 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.1 | 0.9 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.1 | 1.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 1.4 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 3.0 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 1.1 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.8 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 1.5 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.2 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.0 | 0.7 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 1.0 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 0.9 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.9 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 0.8 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 0.4 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.0 | 1.2 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.4 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 1.5 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.7 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.2 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 0.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.6 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.7 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.3 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 0.3 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 0.2 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.2 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.2 | 1.4 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.2 | 3.0 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 1.8 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.1 | 2.4 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.1 | 1.1 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 1.0 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.1 | 2.1 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 0.7 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.1 | 1.9 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.1 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.0 | 0.5 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 0.6 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 2.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.4 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.0 | 0.6 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.3 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.7 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.5 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.6 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
0.0 | 1.0 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.5 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 0.3 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.4 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 1.4 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.2 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.9 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.2 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.0 | 0.2 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 1.2 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
0.0 | 0.6 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.0 | 0.2 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.3 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
0.0 | 1.4 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | Genes involved in Downstream signal transduction |
0.0 | 0.3 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
0.0 | 0.3 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 0.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.5 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.4 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.0 | 0.2 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.4 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | Genes involved in Signaling by EGFR in Cancer |