Motif ID: Tcf3
Z-value: 0.960

Transcription factors associated with Tcf3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tcf3 | ENSMUSG00000020167.8 | Tcf3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tcf3 | mm10_v2_chr10_-_80433615_80433655 | 0.67 | 2.3e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.5 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
0.8 | 3.8 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.7 | 2.0 | GO:0021649 | vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) |
0.7 | 2.0 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913) |
0.5 | 2.2 | GO:0060032 | notochord regression(GO:0060032) |
0.5 | 1.5 | GO:1990523 | bone regeneration(GO:1990523) |
0.5 | 5.4 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.5 | 1.4 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.4 | 1.2 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.4 | 3.1 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.4 | 1.5 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.4 | 1.5 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
0.4 | 1.1 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.4 | 1.1 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.4 | 3.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.4 | 4.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.3 | 1.0 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
0.3 | 1.3 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.3 | 1.2 | GO:0061743 | motor learning(GO:0061743) |
0.3 | 2.4 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
0.3 | 1.2 | GO:0010288 | response to lead ion(GO:0010288) |
0.3 | 0.6 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
0.3 | 0.8 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.3 | 1.1 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.3 | 1.8 | GO:0046549 | phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549) |
0.3 | 1.8 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.2 | 3.3 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
0.2 | 1.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.2 | 0.9 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
0.2 | 0.9 | GO:0030202 | heparin metabolic process(GO:0030202) |
0.2 | 0.7 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826) |
0.2 | 1.1 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.2 | 0.9 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.2 | 0.6 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.2 | 1.5 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.2 | 1.4 | GO:0007144 | female meiosis I(GO:0007144) |
0.2 | 1.6 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.2 | 0.6 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.2 | 0.6 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.2 | 0.6 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.2 | 0.6 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) serotonin secretion by platelet(GO:0002554) |
0.2 | 0.6 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.2 | 2.8 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
0.2 | 2.2 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
0.2 | 0.6 | GO:0051105 | regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) |
0.2 | 0.7 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.2 | 0.5 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.2 | 1.8 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 1.0 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.2 | 0.5 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.2 | 1.8 | GO:0014841 | skeletal muscle satellite cell proliferation(GO:0014841) |
0.1 | 0.4 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
0.1 | 0.3 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
0.1 | 0.5 | GO:0051593 | response to folic acid(GO:0051593) |
0.1 | 1.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 1.2 | GO:0042534 | tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534) |
0.1 | 0.5 | GO:1903998 | regulation of eating behavior(GO:1903998) |
0.1 | 2.7 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
0.1 | 1.3 | GO:0001977 | renal system process involved in regulation of blood volume(GO:0001977) |
0.1 | 2.7 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.1 | 2.0 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
0.1 | 0.5 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 0.3 | GO:1903011 | negative regulation of bone development(GO:1903011) |
0.1 | 1.0 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.1 | 0.2 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.1 | 0.3 | GO:2000850 | protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
0.1 | 1.4 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.1 | 0.3 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
0.1 | 0.3 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
0.1 | 0.9 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
0.1 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 0.3 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.1 | 0.7 | GO:0043201 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
0.1 | 0.2 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) |
0.1 | 0.5 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.1 | 0.5 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.1 | 0.5 | GO:0097473 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
0.1 | 0.6 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 0.4 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
0.1 | 0.5 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
0.1 | 0.6 | GO:0070458 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
0.1 | 1.0 | GO:0009650 | UV protection(GO:0009650) |
0.1 | 0.7 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 0.6 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
0.1 | 0.4 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 0.4 | GO:0006868 | glutamine transport(GO:0006868) |
0.1 | 1.1 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.1 | 0.5 | GO:0021984 | adenohypophysis development(GO:0021984) |
0.1 | 0.2 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
0.1 | 0.1 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) |
0.1 | 0.4 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
0.1 | 0.8 | GO:0002693 | positive regulation of cellular extravasation(GO:0002693) |
0.1 | 1.6 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.1 | 0.2 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 0.2 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
0.1 | 0.4 | GO:0032439 | endosome localization(GO:0032439) |
0.1 | 0.4 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.1 | 0.5 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.1 | 0.7 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.3 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.1 | 0.3 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
0.1 | 0.5 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
0.1 | 0.3 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.1 | 2.6 | GO:0035329 | hippo signaling(GO:0035329) |
0.1 | 0.5 | GO:0042095 | interferon-gamma biosynthetic process(GO:0042095) |
0.1 | 0.8 | GO:0060482 | lobar bronchus development(GO:0060482) |
0.1 | 0.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
0.1 | 0.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 0.3 | GO:1905245 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
0.1 | 0.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.1 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.1 | 0.3 | GO:0060017 | parathyroid gland development(GO:0060017) |
0.1 | 0.2 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.1 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.1 | 0.2 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
0.1 | 0.3 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.1 | 0.9 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.0 | 0.5 | GO:0045945 | positive regulation of transcription from RNA polymerase III promoter(GO:0045945) |
0.0 | 0.1 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.0 | 0.7 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.6 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.0 | 0.2 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.0 | 0.7 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.0 | 0.3 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.3 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.0 | 0.1 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
0.0 | 0.3 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
0.0 | 0.9 | GO:0042493 | response to drug(GO:0042493) |
0.0 | 0.3 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
0.0 | 0.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.5 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.0 | 0.5 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
0.0 | 0.5 | GO:0080111 | DNA demethylation(GO:0080111) |
0.0 | 0.9 | GO:0010719 | negative regulation of epithelial to mesenchymal transition(GO:0010719) |
0.0 | 0.3 | GO:2001054 | negative regulation of mesenchymal cell apoptotic process(GO:2001054) |
0.0 | 0.8 | GO:0042104 | positive regulation of activated T cell proliferation(GO:0042104) |
0.0 | 0.1 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.0 | 1.9 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.0 | 0.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.0 | 0.2 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.0 | 0.1 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
0.0 | 0.5 | GO:0034142 | toll-like receptor 4 signaling pathway(GO:0034142) |
0.0 | 0.2 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385) |
0.0 | 0.8 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.0 | 0.3 | GO:0006560 | proline metabolic process(GO:0006560) |
0.0 | 0.2 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
0.0 | 0.5 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.0 | 0.1 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
0.0 | 0.2 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.0 | 0.1 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.0 | 0.4 | GO:0010225 | response to UV-C(GO:0010225) |
0.0 | 0.7 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.4 | GO:0021924 | cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930) |
0.0 | 0.6 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.2 | GO:0016264 | gap junction assembly(GO:0016264) |
0.0 | 0.1 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.0 | 0.3 | GO:0006833 | water transport(GO:0006833) |
0.0 | 0.1 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
0.0 | 0.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.4 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.4 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.7 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.1 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
0.0 | 0.4 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
0.0 | 0.2 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) |
0.0 | 0.6 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.0 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
0.0 | 0.3 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.0 | 0.2 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.6 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
0.0 | 0.5 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
0.0 | 0.4 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
0.0 | 0.6 | GO:0034629 | cellular protein complex localization(GO:0034629) |
0.0 | 0.5 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
0.0 | 0.2 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
0.0 | 0.3 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.0 | 1.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 1.5 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.4 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.0 | 0.2 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.0 | 0.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 0.1 | GO:0060347 | heart trabecula formation(GO:0060347) |
0.0 | 0.7 | GO:2000573 | positive regulation of DNA biosynthetic process(GO:2000573) |
0.0 | 0.7 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.0 | 0.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.0 | 0.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.5 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.4 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.0 | 1.2 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.3 | GO:0006767 | water-soluble vitamin metabolic process(GO:0006767) |
0.0 | 0.1 | GO:0061052 | negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) |
0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.3 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
0.0 | 0.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.0 | 0.4 | GO:0000154 | rRNA modification(GO:0000154) |
0.0 | 0.2 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
0.0 | 0.4 | GO:0045103 | intermediate filament-based process(GO:0045103) |
0.0 | 0.4 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
0.0 | 0.2 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 0.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.0 | 0.4 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
0.0 | 1.0 | GO:0045089 | positive regulation of innate immune response(GO:0045089) |
0.0 | 0.0 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
0.0 | 0.3 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 0.2 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
0.0 | 0.1 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.3 | 4.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.3 | 0.9 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
0.3 | 1.2 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.3 | 1.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.3 | 0.8 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.2 | 2.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.2 | 2.4 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.2 | 0.9 | GO:0097149 | centralspindlin complex(GO:0097149) |
0.2 | 2.2 | GO:0097542 | ciliary tip(GO:0097542) |
0.2 | 0.9 | GO:0016011 | dystroglycan complex(GO:0016011) |
0.1 | 0.7 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.1 | 0.5 | GO:0043209 | myelin sheath(GO:0043209) |
0.1 | 0.7 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 1.4 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 0.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 0.8 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.1 | 1.3 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 0.3 | GO:0048179 | activin receptor complex(GO:0048179) |
0.1 | 0.5 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.1 | 0.4 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.1 | 0.4 | GO:1990357 | terminal web(GO:1990357) |
0.1 | 0.6 | GO:0005827 | polar microtubule(GO:0005827) |
0.1 | 0.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 2.1 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 0.3 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
0.1 | 0.2 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.1 | 0.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 0.5 | GO:0001940 | male pronucleus(GO:0001940) |
0.1 | 0.4 | GO:0045179 | apical cortex(GO:0045179) |
0.1 | 1.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.1 | 0.4 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 0.4 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 1.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 0.3 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
0.1 | 0.6 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.1 | 1.0 | GO:0031527 | filopodium membrane(GO:0031527) |
0.1 | 0.4 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 0.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.1 | GO:0044302 | dentate gyrus mossy fiber(GO:0044302) |
0.0 | 0.6 | GO:0031090 | organelle membrane(GO:0031090) |
0.0 | 0.8 | GO:0031045 | dense core granule(GO:0031045) |
0.0 | 2.4 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.6 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.0 | 1.2 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.2 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.0 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 2.6 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.6 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.4 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.1 | GO:0031983 | vesicle lumen(GO:0031983) |
0.0 | 0.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.5 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.6 | GO:0000800 | lateral element(GO:0000800) |
0.0 | 0.1 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
0.0 | 0.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.2 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.0 | 0.6 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.2 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 1.1 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.2 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.0 | 0.2 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.0 | 4.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 1.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.3 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.0 | 0.3 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.4 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.0 | 0.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.2 | GO:0033263 | CORVET complex(GO:0033263) |
0.0 | 0.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 0.6 | GO:0070822 | Sin3-type complex(GO:0070822) |
0.0 | 3.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 0.1 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
0.0 | 0.3 | GO:0031105 | septin complex(GO:0031105) |
0.0 | 0.4 | GO:0099568 | cell cortex(GO:0005938) cytoplasmic region(GO:0099568) |
0.0 | 4.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.7 | GO:0005901 | caveola(GO:0005901) |
0.0 | 1.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.3 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 1.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 2.3 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 0.2 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 2.4 | GO:0005819 | spindle(GO:0005819) |
0.0 | 1.0 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.0 | 0.2 | GO:0097449 | astrocyte projection(GO:0097449) |
0.0 | 0.1 | GO:0070695 | FHF complex(GO:0070695) |
0.0 | 0.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.0 | 0.3 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 0.4 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 1.0 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 1.7 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 0.4 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.8 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.6 | GO:0045177 | apical part of cell(GO:0045177) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.5 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
0.8 | 3.2 | GO:0050436 | microfibril binding(GO:0050436) |
0.5 | 1.6 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.5 | 2.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.5 | 4.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.4 | 1.1 | GO:0070052 | collagen V binding(GO:0070052) |
0.4 | 1.8 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.3 | 2.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.3 | 3.6 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.3 | 2.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.3 | 2.0 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.3 | 0.9 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.3 | 1.0 | GO:0004096 | aminoacylase activity(GO:0004046) catalase activity(GO:0004096) |
0.2 | 0.6 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
0.2 | 0.6 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.2 | 0.7 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.2 | 0.5 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.2 | 1.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.2 | 0.6 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.1 | 0.6 | GO:0019863 | IgE binding(GO:0019863) |
0.1 | 0.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.1 | 0.5 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.1 | 0.3 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.1 | 0.5 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
0.1 | 4.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 0.3 | GO:0052743 | inositol tetrakisphosphate phosphatase activity(GO:0052743) |
0.1 | 1.7 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 0.3 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.1 | 0.3 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
0.1 | 0.3 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 3.7 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 1.8 | GO:0051861 | glycolipid binding(GO:0051861) |
0.1 | 0.7 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 0.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 3.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 1.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.1 | 0.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.1 | 1.9 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 0.7 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
0.1 | 1.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 1.3 | GO:0033764 | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764) |
0.1 | 2.8 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.1 | 3.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.1 | 1.2 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.1 | 1.3 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
0.1 | 0.5 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 0.4 | GO:0043532 | angiostatin binding(GO:0043532) |
0.1 | 0.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.1 | 0.4 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
0.1 | 0.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 2.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 3.9 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 0.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 0.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 1.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.1 | 0.3 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.1 | 0.4 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.1 | 0.7 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 0.2 | GO:0051425 | PTB domain binding(GO:0051425) |
0.1 | 0.6 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
0.1 | 0.5 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030) |
0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 1.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.1 | 0.3 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.1 | 0.2 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.1 | 0.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.1 | 0.4 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 1.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.1 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.6 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 4.3 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.8 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.0 | 0.6 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.0 | 0.3 | GO:0008494 | translation activator activity(GO:0008494) |
0.0 | 0.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.3 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.0 | 0.6 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.5 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.0 | 0.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.2 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.0 | 0.6 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 2.3 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.2 | GO:0035877 | death effector domain binding(GO:0035877) |
0.0 | 1.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.5 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
0.0 | 0.2 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 0.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 0.4 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.0 | 0.4 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
0.0 | 0.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 1.0 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 0.3 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 0.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.4 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.3 | GO:0071949 | FAD binding(GO:0071949) |
0.0 | 0.6 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.0 | 0.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.0 | 1.1 | GO:0042054 | histone methyltransferase activity(GO:0042054) |
0.0 | 0.5 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 1.0 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.0 | 0.2 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.6 | GO:0051183 | vitamin transporter activity(GO:0051183) |
0.0 | 1.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.4 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.2 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) |
0.0 | 0.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.3 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.3 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 2.0 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.3 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.3 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 0.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.1 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.1 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 0.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.8 | GO:0015108 | chloride transmembrane transporter activity(GO:0015108) |
0.0 | 0.6 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.0 | 0.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 0.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.0 | 0.1 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.0 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.2 | 1.4 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.2 | 4.7 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.2 | 5.0 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 0.9 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.1 | 1.2 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.1 | 2.5 | PID_LYMPH_ANGIOGENESIS_PATHWAY | VEGFR3 signaling in lymphatic endothelium |
0.1 | 1.8 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.1 | 2.7 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 2.0 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.0 | 0.9 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 1.1 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.2 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 1.6 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 1.0 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.4 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 3.2 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.5 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 1.1 | PID_IGF1_PATHWAY | IGF1 pathway |
0.0 | 0.7 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.0 | 0.5 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.1 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 0.5 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.3 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 2.6 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 0.6 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 3.7 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 1.2 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.3 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 0.4 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.6 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.4 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 0.7 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.6 | PID_ENDOTHELIN_PATHWAY | Endothelins |
0.0 | 0.9 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 0.3 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 0.2 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.3 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 0.6 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 0.7 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.9 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 0.1 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 0.2 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 0.3 | PID_EPO_PATHWAY | EPO signaling pathway |
0.0 | 0.4 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 0.6 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 0.3 | PID_IFNG_PATHWAY | IFN-gamma pathway |
0.0 | 0.7 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
0.0 | 0.4 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.1 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.1 | PID_ALK2_PATHWAY | ALK2 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.0 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.2 | 3.4 | REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION | Genes involved in Incretin Synthesis, Secretion, and Inactivation |
0.2 | 2.0 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.2 | 1.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 2.2 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 0.7 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.1 | 3.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 4.5 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 1.0 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.1 | 1.4 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 0.5 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.1 | 0.3 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 2.5 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 2.7 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.1 | 1.1 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 0.6 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 0.5 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 4.7 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 0.6 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.1 | 1.8 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.1 | 0.9 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.1 | 0.4 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 0.6 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.0 | 0.7 | REACTOME_AQUAPORIN_MEDIATED_TRANSPORT | Genes involved in Aquaporin-mediated transport |
0.0 | 0.7 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 1.6 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.0 | 1.2 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.5 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 3.1 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 3.9 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.0 | 0.5 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.0 | 0.3 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 0.6 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.0 | 1.2 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.6 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 1.3 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.2 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.0 | 1.0 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 1.4 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
0.0 | 0.3 | REACTOME_CD28_DEPENDENT_VAV1_PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
0.0 | 0.4 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.8 | REACTOME_IL_3_5_AND_GM_CSF_SIGNALING | Genes involved in Interleukin-3, 5 and GM-CSF signaling |
0.0 | 0.7 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
0.0 | 0.6 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
0.0 | 0.6 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 0.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 1.6 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.3 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.2 | REACTOME_IL_2_SIGNALING | Genes involved in Interleukin-2 signaling |
0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.2 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 0.1 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 0.8 | REACTOME_SIGNALING_BY_FGFR | Genes involved in Signaling by FGFR |
0.0 | 0.9 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.2 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.0 | 0.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.3 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 0.3 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |