Motif ID: Esr1
Z-value: 0.599

Transcription factors associated with Esr1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Esr1 | ENSMUSG00000019768.10 | Esr1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Esr1 | mm10_v2_chr10_+_4710119_4710166 | 0.19 | 4.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.5 | 1.9 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.4 | 1.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.4 | 1.2 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.3 | 1.4 | GO:0002481 | antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) |
0.3 | 1.0 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.3 | 1.0 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
0.3 | 1.0 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356) |
0.3 | 0.9 | GO:0016115 | terpenoid catabolic process(GO:0016115) |
0.3 | 0.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.3 | 1.7 | GO:0032439 | endosome localization(GO:0032439) |
0.3 | 1.1 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.3 | 0.8 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
0.3 | 0.5 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
0.2 | 0.7 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.2 | 1.0 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.2 | 0.7 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.2 | 0.8 | GO:0030091 | protein repair(GO:0030091) |
0.2 | 0.6 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
0.2 | 0.6 | GO:0044413 | regulation of lung blood pressure(GO:0014916) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
0.2 | 0.6 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.2 | 0.6 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.2 | 0.6 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.2 | 0.9 | GO:0019659 | fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.2 | 1.5 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
0.2 | 0.5 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
0.1 | 0.6 | GO:0006751 | glutathione catabolic process(GO:0006751) |
0.1 | 0.4 | GO:0046061 | dATP catabolic process(GO:0046061) |
0.1 | 0.9 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 1.7 | GO:2000254 | regulation of male germ cell proliferation(GO:2000254) |
0.1 | 0.6 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) positive regulation of neurotrophin production(GO:0032901) |
0.1 | 0.6 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.4 | GO:2000510 | regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.1 | 0.6 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.1 | 0.3 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.1 | 0.3 | GO:0060129 | BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) |
0.1 | 0.3 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
0.1 | 0.4 | GO:0002901 | brain renin-angiotensin system(GO:0002035) mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of arachidonic acid secretion(GO:0090238) |
0.1 | 0.3 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.1 | 0.4 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.1 | 1.0 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.1 | 0.7 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.1 | 0.3 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
0.1 | 0.3 | GO:0002176 | male germ cell proliferation(GO:0002176) |
0.1 | 0.4 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.1 | 0.2 | GO:1990869 | response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) |
0.1 | 0.3 | GO:0090204 | protein localization to nuclear pore(GO:0090204) positive regulation of calcium-transporting ATPase activity(GO:1901896) |
0.1 | 1.4 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.1 | 1.1 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
0.1 | 0.3 | GO:0050787 | glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) regulation of cellular amino acid biosynthetic process(GO:2000282) positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
0.1 | 0.4 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
0.1 | 0.5 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.1 | 0.2 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.1 | 0.2 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
0.1 | 0.3 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.1 | 0.6 | GO:0071865 | regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866) |
0.1 | 0.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.1 | 0.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 0.2 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.6 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
0.1 | 0.2 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 0.1 | GO:0006532 | aspartate biosynthetic process(GO:0006532) |
0.1 | 0.4 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
0.1 | 0.2 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.1 | 0.5 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.1 | 0.2 | GO:0036166 | phenotypic switching(GO:0036166) |
0.1 | 0.2 | GO:0010958 | regulation of amino acid import(GO:0010958) |
0.1 | 0.1 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
0.1 | 0.1 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.1 | 0.2 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.1 | 0.2 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.1 | 0.7 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.1 | 0.4 | GO:0000279 | M phase(GO:0000279) |
0.1 | 0.2 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.1 | 0.2 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.1 | 0.3 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.0 | 0.3 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
0.0 | 0.2 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.0 | 0.5 | GO:0060179 | male mating behavior(GO:0060179) |
0.0 | 0.2 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.0 | 0.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 0.1 | GO:1903998 | regulation of eating behavior(GO:1903998) |
0.0 | 0.1 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
0.0 | 0.1 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.0 | 0.2 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 0.4 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.0 | 0.3 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.0 | 0.4 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.0 | 0.4 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.1 | GO:0016132 | brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132) |
0.0 | 1.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.2 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.0 | 0.3 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.0 | 0.2 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.0 | 0.5 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
0.0 | 0.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.0 | 0.1 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
0.0 | 0.1 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.0 | 0.2 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
0.0 | 0.7 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
0.0 | 0.1 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.0 | 0.1 | GO:0061744 | motor behavior(GO:0061744) |
0.0 | 0.2 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
0.0 | 0.2 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.0 | 0.3 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.0 | 0.3 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 0.5 | GO:0071459 | protein localization to chromosome, centromeric region(GO:0071459) |
0.0 | 0.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.1 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449) |
0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 0.3 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
0.0 | 0.1 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.0 | 0.1 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
0.0 | 0.1 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.0 | 0.5 | GO:0050909 | sensory perception of taste(GO:0050909) |
0.0 | 0.3 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
0.0 | 0.3 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
0.0 | 0.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.0 | 0.2 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
0.0 | 0.1 | GO:0080184 | response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184) |
0.0 | 0.3 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.0 | 0.4 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 1.1 | GO:0043039 | tRNA aminoacylation(GO:0043039) |
0.0 | 0.1 | GO:0051126 | negative regulation of actin nucleation(GO:0051126) |
0.0 | 0.2 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation by host of viral genome replication(GO:0044829) |
0.0 | 0.4 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.0 | 0.1 | GO:0009838 | abscission(GO:0009838) |
0.0 | 0.1 | GO:0018343 | protein farnesylation(GO:0018343) |
0.0 | 0.3 | GO:0043589 | skin morphogenesis(GO:0043589) |
0.0 | 0.0 | GO:0010616 | negative regulation of cardiac muscle adaptation(GO:0010616) |
0.0 | 0.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.0 | 0.2 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
0.0 | 0.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.0 | 0.0 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
0.0 | 0.4 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.0 | 0.3 | GO:0006857 | oligopeptide transport(GO:0006857) |
0.0 | 0.2 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.0 | 0.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.1 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.0 | 0.7 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
0.0 | 0.3 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.0 | 0.4 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.0 | 0.2 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.3 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.7 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.1 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.0 | 0.2 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.0 | 0.1 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.0 | 0.1 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
0.0 | 0.9 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.2 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
0.0 | 0.1 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
0.0 | 0.2 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.0 | 0.1 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.0 | 0.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.0 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.0 | 0.6 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.1 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
0.0 | 1.0 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.0 | 0.5 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 0.1 | GO:0019695 | choline metabolic process(GO:0019695) |
0.0 | 0.2 | GO:0045003 | DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
0.0 | 0.2 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.0 | 0.3 | GO:0006825 | copper ion transport(GO:0006825) |
0.0 | 0.3 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.2 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.0 | 0.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.0 | 0.1 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.0 | 0.3 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 1.0 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
0.0 | 0.2 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.1 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.0 | 0.2 | GO:0021559 | trigeminal nerve development(GO:0021559) |
0.0 | 0.2 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.0 | 0.2 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
0.0 | 0.1 | GO:0060539 | diaphragm development(GO:0060539) |
0.0 | 0.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.2 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.0 | 0.1 | GO:0006265 | DNA topological change(GO:0006265) |
0.0 | 0.1 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
0.0 | 0.1 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.0 | 0.2 | GO:0032094 | response to food(GO:0032094) |
0.0 | 0.1 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.0 | 0.1 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
0.0 | 0.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.2 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.0 | 0.4 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.2 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
0.0 | 0.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.0 | 0.1 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 0.2 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
0.0 | 0.1 | GO:1990564 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 4.5 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.4 | 2.5 | GO:0097452 | GAIT complex(GO:0097452) |
0.3 | 1.0 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.3 | 0.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.3 | 1.7 | GO:0045179 | apical cortex(GO:0045179) |
0.3 | 1.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 0.8 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.1 | 0.5 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
0.1 | 1.2 | GO:0061574 | ASAP complex(GO:0061574) |
0.1 | 1.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.4 | GO:0000801 | central element(GO:0000801) |
0.1 | 1.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 0.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.1 | 0.7 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.1 | 0.3 | GO:0005584 | collagen type I trimer(GO:0005584) |
0.1 | 0.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 0.3 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.1 | 0.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.1 | 0.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 0.3 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.1 | 0.7 | GO:0042611 | MHC protein complex(GO:0042611) |
0.1 | 0.3 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.1 | 0.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.2 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.1 | 0.5 | GO:0033061 | DNA recombinase mediator complex(GO:0033061) |
0.1 | 0.2 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.1 | 0.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.1 | 0.3 | GO:0030120 | vesicle coat(GO:0030120) |
0.1 | 0.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 0.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.1 | GO:0071920 | cleavage body(GO:0071920) |
0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
0.0 | 0.3 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 0.4 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.0 | 0.1 | GO:1903349 | omegasome membrane(GO:1903349) |
0.0 | 0.3 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.0 | 0.4 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 1.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 0.2 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.2 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 0.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.1 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.0 | 0.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
0.0 | 0.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.2 | GO:0005638 | lamin filament(GO:0005638) |
0.0 | 0.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.0 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.1 | GO:0072487 | MSL complex(GO:0072487) |
0.0 | 1.8 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.1 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.0 | 0.1 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.0 | 1.1 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.2 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
0.0 | 0.2 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.2 | GO:0089701 | commitment complex(GO:0000243) U2AF(GO:0089701) |
0.0 | 0.4 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.1 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.0 | 0.2 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.0 | 0.1 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
0.0 | 0.8 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.1 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.0 | 0.2 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 1.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.2 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.1 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.1 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 0.1 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.0 | 0.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 0.4 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 0.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.9 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.4 | 1.2 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.3 | 1.0 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.2 | 0.7 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.2 | 0.7 | GO:0030629 | U6 snRNA 3'-end binding(GO:0030629) |
0.2 | 4.2 | GO:0030228 | lipoprotein particle receptor activity(GO:0030228) |
0.2 | 0.9 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 1.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 0.6 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.2 | 1.0 | GO:0043199 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) sulfate binding(GO:0043199) |
0.2 | 1.0 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.2 | 0.9 | GO:0019841 | retinol binding(GO:0019841) |
0.1 | 1.0 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.1 | 0.6 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
0.1 | 0.8 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.1 | 0.5 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
0.1 | 0.6 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.1 | 0.3 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.1 | 1.0 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 0.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 0.4 | GO:0030984 | kininogen binding(GO:0030984) |
0.1 | 0.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 0.4 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.1 | 0.2 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
0.1 | 0.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.1 | 0.3 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.1 | 0.4 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.1 | 0.6 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.1 | 0.3 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 1.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 0.5 | GO:0008494 | translation activator activity(GO:0008494) |
0.1 | 0.2 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.1 | 0.4 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 0.4 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.1 | 0.2 | GO:0009041 | uridylate kinase activity(GO:0009041) |
0.1 | 1.8 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.1 | 0.4 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.1 | 0.3 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.9 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 0.3 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.1 | 0.7 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.1 | 0.4 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.1 | 0.4 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 0.2 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618) |
0.1 | 0.4 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.4 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.1 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.0 | 0.5 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.0 | 0.3 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.0 | 0.3 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.0 | 0.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.1 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
0.0 | 0.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.0 | 0.2 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.0 | 0.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.0 | 0.1 | GO:0009918 | sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598) |
0.0 | 0.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.0 | 0.2 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
0.0 | 0.5 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.0 | 0.3 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.0 | 0.2 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.0 | 0.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.0 | 0.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.0 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.0 | 0.8 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.0 | 0.2 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 0.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.4 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.0 | 1.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.2 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.0 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
0.0 | 0.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.3 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
0.0 | 0.5 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.0 | 0.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.0 | 0.2 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.0 | 0.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.2 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.0 | 0.3 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
0.0 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.0 | 0.5 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 0.4 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.2 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.4 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 1.1 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.1 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.0 | 0.2 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.2 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.0 | 0.1 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.0 | 0.2 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 0.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.1 | GO:0030519 | snoRNP binding(GO:0030519) |
0.0 | 0.2 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.2 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
0.0 | 1.2 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.2 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.0 | 0.5 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.1 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 0.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.0 | 0.1 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.0 | 0.0 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.0 | 0.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 2.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.1 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.1 | GO:0032564 | dATP binding(GO:0032564) |
0.0 | 0.1 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.0 | 0.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.2 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.0 | 0.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.4 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 1.7 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.1 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.0 | 0.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 0.0 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.0 | 0.1 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.0 | 0.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.0 | 0.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 0.0 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.0 | 0.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.2 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 4.7 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 1.0 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 1.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.3 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.0 | 0.3 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.0 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.0 | 1.1 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 0.7 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 0.7 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.0 | 0.7 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.2 | PID_EPO_PATHWAY | EPO signaling pathway |
0.0 | 0.2 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.2 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 0.1 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.0 | 0.1 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.7 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.1 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 0.4 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.0 | 0.2 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
0.0 | 0.2 | PID_ATM_PATHWAY | ATM pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
0.1 | 0.3 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.1 | 3.5 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.1 | 0.6 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 1.1 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.1 | 0.6 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.0 | 1.1 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.0 | 0.7 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.3 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 2.2 | REACTOME_ER_PHAGOSOME_PATHWAY | Genes involved in ER-Phagosome pathway |
0.0 | 0.6 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 0.6 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.7 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.7 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 0.3 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 0.4 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 1.3 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.4 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.3 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.6 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.6 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.5 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.2 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.1 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.0 | 0.6 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
0.0 | 0.3 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.6 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
0.0 | 0.8 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.1 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 0.3 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 1.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.4 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.1 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.0 | 1.0 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.0 | 0.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 1.2 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.0 | 0.3 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.6 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.3 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.9 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.9 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | Genes involved in Host Interactions of HIV factors |
0.0 | 0.1 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.2 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.2 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 0.2 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.1 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.2 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.0 | 0.2 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |