Motif ID: Hoxc9
Z-value: 0.688

Transcription factors associated with Hoxc9:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxc9 | ENSMUSG00000036139.6 | Hoxc9 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hoxc9 | mm10_v2_chr15_+_102977032_102977032 | -0.26 | 2.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.8 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
0.5 | 1.6 | GO:0003219 | atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219) |
0.4 | 1.8 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.3 | 2.3 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.2 | 2.0 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.1 | 0.4 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
0.1 | 1.4 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
0.1 | 0.4 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.6 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
0.1 | 0.7 | GO:0061042 | vascular wound healing(GO:0061042) |
0.1 | 0.2 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
0.1 | 0.9 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.1 | 1.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.1 | 0.2 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.1 | 0.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.0 | 0.6 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.0 | 0.3 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
0.0 | 0.4 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
0.0 | 0.1 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.0 | 0.5 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.0 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.9 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.0 | 0.2 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 0.7 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.0 | GO:0044308 | axonal spine(GO:0044308) |
0.3 | 1.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.3 | 2.8 | GO:0005915 | zonula adherens(GO:0005915) |
0.3 | 1.8 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.1 | 0.4 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 0.6 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.1 | 0.2 | GO:0071914 | prominosome(GO:0071914) |
0.1 | 0.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.3 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.0 | 0.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.2 | GO:0042581 | specific granule(GO:0042581) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.3 | 1.3 | GO:0055100 | adiponectin binding(GO:0055100) |
0.2 | 2.0 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 0.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 0.4 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.1 | 0.7 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 0.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.1 | 0.3 | GO:0038025 | reelin receptor activity(GO:0038025) |
0.1 | 0.2 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.1 | 1.1 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.0 | 1.6 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.1 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.0 | 0.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.1 | GO:0030151 | molybdenum ion binding(GO:0030151) |
0.0 | 0.2 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.3 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 2.8 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.0 | 1.8 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
0.0 | 1.6 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 1.3 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.8 | NABA_COLLAGENS | Genes encoding collagen proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 2.3 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 1.8 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.0 | 0.3 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
0.0 | 1.7 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.8 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.3 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.7 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |