Motif ID: Bhlhe40
Z-value: 0.607

Transcription factors associated with Bhlhe40:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Bhlhe40 | ENSMUSG00000030103.5 | Bhlhe40 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Bhlhe40 | mm10_v2_chr6_+_108660772_108660874 | 0.54 | 2.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.4 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
0.4 | 2.0 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
0.2 | 1.0 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055) |
0.1 | 0.5 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
0.1 | 2.6 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.1 | 1.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 1.0 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
0.1 | 0.3 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
0.1 | 0.2 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
0.1 | 0.5 | GO:0015808 | L-alanine transport(GO:0015808) |
0.1 | 0.2 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.1 | 0.3 | GO:1903012 | positive regulation of bone development(GO:1903012) |
0.0 | 0.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.0 | 2.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.7 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.3 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.2 | GO:0030242 | pexophagy(GO:0030242) |
0.0 | 0.3 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
0.0 | 0.1 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) positive regulation of neuronal action potential(GO:1904457) |
0.0 | 0.3 | GO:0001675 | acrosome assembly(GO:0001675) |
0.0 | 0.7 | GO:0097178 | ruffle assembly(GO:0097178) |
0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.5 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
0.0 | 0.1 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
0.0 | 0.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.1 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
0.0 | 0.1 | GO:0070842 | aggresome assembly(GO:0070842) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.0 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.3 | 2.5 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.2 | 1.3 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 1.0 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 0.3 | GO:0032280 | symmetric synapse(GO:0032280) |
0.0 | 0.7 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.7 | GO:0044306 | neuron projection terminus(GO:0044306) |
0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 3.3 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.4 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.2 | 1.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.2 | 0.5 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.1 | 2.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 0.7 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 2.5 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.1 | 0.4 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 0.7 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 2.0 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 0.2 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.1 | 1.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.0 | 0.3 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 0.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.1 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 0.3 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.0 | 0.3 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 0.3 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.7 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.5 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 4.2 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 2.0 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.3 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.2 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.0 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |