Motif ID: Hsf4
Z-value: 0.956

Transcription factors associated with Hsf4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hsf4 | ENSMUSG00000033249.4 | Hsf4 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 5.2 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
0.6 | 3.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.5 | 1.5 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
0.3 | 1.8 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.3 | 1.2 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
0.2 | 0.7 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
0.2 | 0.9 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.2 | 0.9 | GO:0007412 | axon target recognition(GO:0007412) |
0.2 | 0.6 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.2 | 0.6 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.2 | 0.6 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.2 | 1.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.2 | 0.7 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.2 | 0.6 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
0.1 | 0.6 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
0.1 | 0.5 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 0.4 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.1 | 0.6 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 1.1 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.1 | 1.0 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.1 | 0.8 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 0.3 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.5 | GO:0042228 | interleukin-8 biosynthetic process(GO:0042228) |
0.1 | 0.3 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.1 | 0.5 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.1 | 0.4 | GO:0002188 | translation reinitiation(GO:0002188) |
0.1 | 1.2 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.1 | 0.4 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
0.1 | 0.9 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.1 | 0.3 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.1 | 0.5 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 0.2 | GO:0090187 | positive regulation of pancreatic juice secretion(GO:0090187) |
0.1 | 0.2 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
0.1 | 0.5 | GO:0048254 | snoRNA localization(GO:0048254) |
0.1 | 0.2 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.1 | 0.3 | GO:0015793 | glycerol transport(GO:0015793) |
0.1 | 0.3 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.1 | 0.2 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.1 | 0.2 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
0.1 | 0.7 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 0.2 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.1 | 0.4 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
0.1 | 1.5 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.1 | 0.8 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.1 | 0.3 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.1 | 0.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.1 | 0.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.1 | 0.6 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.1 | 0.2 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
0.1 | 0.4 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.1 | 0.2 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
0.1 | 0.5 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.1 | 0.2 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.1 | 0.2 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.0 | 0.2 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.0 | 0.3 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
0.0 | 0.4 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
0.0 | 0.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.0 | 0.1 | GO:1904154 | protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
0.0 | 0.3 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.0 | 0.7 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
0.0 | 0.3 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.0 | 0.4 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.0 | 0.9 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
0.0 | 0.6 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.0 | 1.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 1.5 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 0.2 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.0 | 0.8 | GO:0019731 | antibacterial humoral response(GO:0019731) |
0.0 | 0.1 | GO:2000812 | response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812) |
0.0 | 0.2 | GO:0090383 | phagosome acidification(GO:0090383) |
0.0 | 0.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.0 | 0.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.0 | 0.1 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
0.0 | 0.2 | GO:0043652 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) engulfment of apoptotic cell(GO:0043652) |
0.0 | 0.7 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.1 | GO:0035771 | interleukin-4-mediated signaling pathway(GO:0035771) |
0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.0 | 0.2 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.0 | 0.4 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.1 | GO:0009414 | response to water deprivation(GO:0009414) |
0.0 | 0.2 | GO:0019695 | choline metabolic process(GO:0019695) |
0.0 | 0.3 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
0.0 | 0.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.0 | 0.1 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.0 | 0.1 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.0 | 0.2 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
0.0 | 1.0 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.0 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.2 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.0 | 0.1 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.0 | 1.5 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 0.2 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
0.0 | 0.7 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.0 | 0.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.3 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.0 | 0.2 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
0.0 | 0.8 | GO:0021591 | ventricular system development(GO:0021591) |
0.0 | 0.3 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.0 | 0.4 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
0.0 | 0.1 | GO:0061450 | trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) |
0.0 | 0.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.1 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 1.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.1 | GO:0032364 | oxygen homeostasis(GO:0032364) |
0.0 | 1.1 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.1 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.0 | 0.2 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.1 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.0 | 0.1 | GO:0051036 | regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
0.0 | 0.5 | GO:0070232 | regulation of T cell apoptotic process(GO:0070232) |
0.0 | 0.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.3 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.0 | 0.1 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.0 | 0.6 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.2 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.0 | 0.7 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.5 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
0.0 | 0.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.6 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
0.0 | 0.0 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.0 | 0.1 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
0.0 | 0.2 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.3 | GO:1903146 | regulation of mitophagy(GO:1903146) |
0.0 | 0.1 | GO:0010818 | T cell chemotaxis(GO:0010818) |
0.0 | 0.1 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.6 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 5.2 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 0.4 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.1 | 1.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 0.3 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.1 | 0.6 | GO:0000938 | GARP complex(GO:0000938) |
0.1 | 0.4 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 0.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 1.3 | GO:0046930 | pore complex(GO:0046930) |
0.1 | 0.8 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 1.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.6 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 1.0 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.1 | 0.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.1 | 0.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 1.0 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 0.2 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.1 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 0.3 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
0.0 | 0.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.0 | 0.4 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.1 | GO:0098842 | postsynaptic early endosome(GO:0098842) |
0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.4 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.0 | 0.4 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.4 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.1 | GO:0097361 | CIA complex(GO:0097361) |
0.0 | 0.1 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.0 | 0.3 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
0.0 | 0.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.4 | GO:0000800 | lateral element(GO:0000800) |
0.0 | 0.1 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.0 | 0.2 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 1.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.1 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.0 | 0.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.2 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.2 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.3 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.2 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.1 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.0 | 0.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 1.4 | GO:0015934 | large ribosomal subunit(GO:0015934) |
0.0 | 0.7 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.9 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 5.2 | GO:0030911 | TPR domain binding(GO:0030911) |
0.3 | 1.0 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
0.3 | 1.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.2 | 0.7 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.2 | 1.5 | GO:0043199 | sulfate binding(GO:0043199) |
0.2 | 0.9 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.2 | 1.3 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.1 | 0.4 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.1 | 0.4 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.1 | 0.5 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.1 | 1.7 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.1 | 0.4 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.1 | 0.4 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.1 | 0.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 0.4 | GO:0034618 | arginine binding(GO:0034618) |
0.1 | 0.5 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.1 | 0.4 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 0.5 | GO:0050700 | CARD domain binding(GO:0050700) |
0.1 | 0.5 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.1 | 0.3 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
0.1 | 1.0 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.1 | 0.3 | GO:0005118 | sevenless binding(GO:0005118) |
0.1 | 0.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.1 | 1.6 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.1 | 0.3 | GO:0015254 | glycerol channel activity(GO:0015254) |
0.1 | 0.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.1 | 0.9 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.1 | 0.6 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.2 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
0.1 | 0.2 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.1 | 0.2 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.1 | 0.7 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.1 | 0.2 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.1 | 0.2 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
0.1 | 0.2 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.1 | 0.5 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.1 | 0.3 | GO:0070883 | pre-miRNA binding(GO:0070883) |
0.1 | 0.3 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.1 | 0.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.1 | 0.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.1 | 0.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 0.3 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.0 | 0.2 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
0.0 | 0.2 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.0 | 1.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 1.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 1.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 1.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.0 | 0.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 0.1 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.8 | GO:0070840 | dynein complex binding(GO:0070840) |
0.0 | 0.2 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.0 | 0.7 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.3 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.8 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 0.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.3 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 0.4 | GO:0070717 | poly-purine tract binding(GO:0070717) |
0.0 | 0.1 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
0.0 | 0.3 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
0.0 | 0.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.7 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 0.2 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
0.0 | 0.1 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.0 | 0.1 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.0 | 0.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 2.1 | GO:0047485 | protein N-terminus binding(GO:0047485) |
0.0 | 1.2 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 0.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.4 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 5.2 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 1.1 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 0.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 1.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 1.8 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.9 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.9 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 0.9 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.8 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.7 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 0.4 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.0 | 0.3 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.2 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.6 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 1.1 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 1.6 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 0.3 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 0.6 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 0.3 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.0 | 0.5 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.2 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.0 | 0.2 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 0.1 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.1 | PID_CD40_PATHWAY | CD40/CD40L signaling |
0.0 | 0.4 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 5.2 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 0.6 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.1 | 1.3 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.5 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.1 | 0.6 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.1 | 0.2 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.0 | 1.3 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 2.8 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 2.7 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.9 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.1 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.6 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.3 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.0 | 3.3 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.5 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.1 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 0.3 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.0 | 0.4 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.7 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 1.1 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
0.0 | 0.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.6 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 0.3 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 0.2 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |