Motif ID: Zkscan3

Z-value: 0.295


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.617.3e-03Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_75422524 0.378 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr11_-_75422586 0.349 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr5_+_24985840 0.312 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr8_-_70760889 0.297 ENSMUST00000038626.8
Mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr1_+_132298606 0.279 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr7_-_81345189 0.242 ENSMUST00000080813.4
Rps17
ribosomal protein S17
chr2_+_32646586 0.234 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr1_+_37997975 0.219 ENSMUST00000027252.7
Eif5b
eukaryotic translation initiation factor 5B
chr7_+_101896340 0.212 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr2_+_104069819 0.211 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr13_-_19395728 0.192 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr7_+_126759601 0.189 ENSMUST00000050201.4
ENSMUST00000057669.9
Mapk3

mitogen-activated protein kinase 3

chr17_+_46110982 0.172 ENSMUST00000024763.3
ENSMUST00000123646.1
Mrps18a

mitochondrial ribosomal protein S18A

chr8_+_33732237 0.167 ENSMUST00000171010.1
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr3_+_146500071 0.167 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr8_+_71396853 0.163 ENSMUST00000002473.8
Babam1
BRISC and BRCA1 A complex member 1
chr18_+_61105844 0.163 ENSMUST00000115268.3
Csf1r
colony stimulating factor 1 receptor
chr17_-_35673738 0.163 ENSMUST00000001565.8
Gtf2h4
general transcription factor II H, polypeptide 4
chr8_+_31091593 0.149 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr4_+_63544747 0.143 ENSMUST00000035301.6
Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr12_+_69724939 0.140 ENSMUST00000021372.5
Atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr17_-_35673517 0.133 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
Gtf2h4



general transcription factor II H, polypeptide 4



chr8_+_94810446 0.128 ENSMUST00000034232.1
Ccl17
chemokine (C-C motif) ligand 17
chr3_+_146499850 0.127 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr1_+_135232045 0.124 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr7_-_127020321 0.122 ENSMUST00000032918.2
Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr11_-_102365111 0.112 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr2_+_156613664 0.109 ENSMUST00000169464.2
ENSMUST00000109567.3
Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr4_+_139192899 0.102 ENSMUST00000102508.3
ENSMUST00000131912.1
ENSMUST00000102507.3
Capzb


capping protein (actin filament) muscle Z-line, beta


chr13_-_38658991 0.102 ENSMUST00000001757.7
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr10_+_80629646 0.100 ENSMUST00000085435.5
Csnk1g2
casein kinase 1, gamma 2
chr12_+_112588753 0.095 ENSMUST00000101029.2
Inf2
inverted formin, FH2 and WH2 domain containing
chr8_-_13200576 0.094 ENSMUST00000165605.2
Grtp1
GH regulated TBC protein 1
chr2_+_104095796 0.092 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr9_+_108648720 0.092 ENSMUST00000098384.2
Gm10621
predicted gene 10621
chr6_+_125552948 0.088 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr8_-_105758570 0.087 ENSMUST00000155038.2
ENSMUST00000013294.9
Gfod2

glucose-fructose oxidoreductase domain containing 2

chr5_-_73338580 0.084 ENSMUST00000087195.5
Ociad2
OCIA domain containing 2
chr5_-_88675613 0.080 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr1_-_173333503 0.078 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr13_-_32851176 0.074 ENSMUST00000091668.5
ENSMUST00000076352.6
Serpinb1a

serine (or cysteine) peptidase inhibitor, clade B, member 1a

chr19_-_10869757 0.073 ENSMUST00000120524.1
ENSMUST00000025645.7
Tmem132a

transmembrane protein 132A

chr2_+_31670714 0.071 ENSMUST00000038474.7
ENSMUST00000137156.1
Exosc2

exosome component 2

chr4_+_15957923 0.069 ENSMUST00000029879.8
ENSMUST00000149069.1
Nbn

nibrin

chr8_+_106893616 0.067 ENSMUST00000047629.5
Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr8_+_70616816 0.064 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chr8_-_106893581 0.062 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
Chtf8



CTF8, chromosome transmission fidelity factor 8



chr10_-_33951190 0.059 ENSMUST00000048222.4
Zufsp
zinc finger with UFM1-specific peptidase domain
chr19_+_6276725 0.056 ENSMUST00000025684.3
Ehd1
EH-domain containing 1
chr15_-_3979432 0.053 ENSMUST00000022791.8
Fbxo4
F-box protein 4
chr5_+_24586721 0.050 ENSMUST00000121863.1
ENSMUST00000088295.4
Chpf2

chondroitin polymerizing factor 2

chr6_-_122856151 0.043 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr6_-_113719880 0.038 ENSMUST00000064993.5
Ghrl
ghrelin
chr9_+_114688782 0.036 ENSMUST00000047404.6
Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chrX_-_17571563 0.029 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chr12_+_32954179 0.029 ENSMUST00000020885.6
Sypl
synaptophysin-like protein
chrX_-_17572241 0.028 ENSMUST00000176638.1
ENSMUST00000026016.6
Fundc1

FUN14 domain containing 1

chr2_-_30194112 0.020 ENSMUST00000113659.1
ENSMUST00000113660.1
Ccbl1

cysteine conjugate-beta lyase 1

chr18_+_82554463 0.020 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr16_-_16359016 0.017 ENSMUST00000023477.7
ENSMUST00000096229.3
ENSMUST00000115749.1
Dnm1l


dynamin 1-like


chr1_+_58795371 0.011 ENSMUST00000027189.8
Casp8
caspase 8
chr8_-_116978908 0.011 ENSMUST00000070577.5
1700030J22Rik
RIKEN cDNA 1700030J22 gene
chr13_-_100786402 0.010 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr7_-_27228605 0.008 ENSMUST00000003850.7
Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr1_-_40790642 0.006 ENSMUST00000039672.5
Mfsd9
major facilitator superfamily domain containing 9
chr11_-_100650693 0.004 ENSMUST00000103119.3
Zfp385c
zinc finger protein 385C
chr2_-_66634952 0.003 ENSMUST00000100064.2
ENSMUST00000100063.2
Scn9a

sodium channel, voltage-gated, type IX, alpha


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.2 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304) histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.0 GO:0035482 intestine smooth muscle contraction(GO:0014827) gastric motility(GO:0035482) gastric emptying(GO:0035483) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464) positive regulation of adipose tissue development(GO:1904179) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
0.0 0.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade