Motif ID: Nfix
Z-value: 1.224

Transcription factors associated with Nfix:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nfix | ENSMUSG00000001911.10 | Nfix |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nfix | mm10_v2_chr8_-_84773381_84773427 | 0.90 | 2.8e-07 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.0 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
1.2 | 3.6 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
1.1 | 3.3 | GO:0071918 | urea transmembrane transport(GO:0071918) |
1.0 | 10.5 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.9 | 4.3 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
0.7 | 3.0 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
0.6 | 5.3 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.6 | 1.7 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.6 | 9.0 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.5 | 1.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.5 | 2.8 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.4 | 2.2 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.4 | 5.8 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.4 | 1.7 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
0.4 | 2.9 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
0.4 | 1.9 | GO:0007403 | glial cell fate determination(GO:0007403) |
0.4 | 1.8 | GO:0015671 | oxygen transport(GO:0015671) |
0.3 | 2.0 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
0.3 | 1.3 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.3 | 1.4 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.3 | 0.8 | GO:0021998 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414) |
0.3 | 0.8 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
0.2 | 4.6 | GO:0032060 | bleb assembly(GO:0032060) |
0.2 | 1.2 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.2 | 1.6 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.2 | 3.1 | GO:0060134 | prepulse inhibition(GO:0060134) |
0.2 | 3.2 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
0.2 | 1.1 | GO:0019532 | oxalate transport(GO:0019532) |
0.2 | 0.8 | GO:0035617 | stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150) |
0.2 | 0.5 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.1 | 0.4 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
0.1 | 0.9 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.1 | 1.1 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 0.4 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
0.1 | 0.5 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
0.1 | 2.8 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
0.1 | 2.9 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
0.1 | 0.5 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
0.1 | 1.5 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.1 | 0.5 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.1 | 4.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 3.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.4 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
0.1 | 0.5 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
0.1 | 0.6 | GO:1903564 | regulation of protein localization to cilium(GO:1903564) |
0.1 | 0.3 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357) |
0.1 | 0.7 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.1 | 0.7 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 0.8 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
0.1 | 0.3 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.1 | 0.6 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 3.3 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.1 | 0.6 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
0.1 | 1.1 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.1 | 1.5 | GO:0048520 | positive regulation of behavior(GO:0048520) |
0.1 | 0.7 | GO:0050957 | equilibrioception(GO:0050957) |
0.1 | 2.5 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.1 | 1.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.1 | 1.4 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
0.1 | 0.5 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.1 | 0.4 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 1.3 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.1 | 0.7 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
0.1 | 0.2 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
0.1 | 1.6 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
0.1 | 3.2 | GO:0060612 | adipose tissue development(GO:0060612) |
0.1 | 0.2 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 1.0 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
0.0 | 0.5 | GO:0070995 | toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995) |
0.0 | 0.2 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.0 | 8.9 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.2 | GO:0045006 | DNA deamination(GO:0045006) |
0.0 | 0.3 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.0 | 0.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.0 | 0.8 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.9 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.0 | 0.6 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.2 | GO:1903756 | regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
0.0 | 0.7 | GO:0031643 | positive regulation of myelination(GO:0031643) |
0.0 | 0.2 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
0.0 | 1.0 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 1.0 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
0.0 | 0.3 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.0 | 0.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.0 | GO:1903546 | receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546) |
0.0 | 0.6 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
0.0 | 1.8 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 2.2 | GO:0007605 | sensory perception of sound(GO:0007605) |
0.0 | 0.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.0 | 0.4 | GO:2000772 | regulation of cellular senescence(GO:2000772) |
0.0 | 0.1 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.0 | 0.1 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.0 | 0.3 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.0 | 0.5 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 1.1 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
0.0 | 1.0 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
0.0 | 0.8 | GO:0009063 | cellular amino acid catabolic process(GO:0009063) |
0.0 | 0.4 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.3 | GO:0043512 | inhibin A complex(GO:0043512) |
0.8 | 3.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.7 | 2.9 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.6 | 3.0 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.4 | 3.0 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.2 | 2.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.2 | 5.8 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.2 | 5.3 | GO:0031430 | M band(GO:0031430) |
0.2 | 3.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.6 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 2.1 | GO:0043218 | compact myelin(GO:0043218) |
0.1 | 0.7 | GO:0097433 | dense body(GO:0097433) |
0.1 | 0.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 0.5 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 1.9 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 0.9 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.1 | 7.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 1.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.1 | 0.5 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 0.3 | GO:0014802 | terminal cisterna(GO:0014802) |
0.1 | 1.4 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.2 | GO:1990032 | parallel fiber(GO:1990032) |
0.0 | 0.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 5.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.8 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 1.7 | GO:0099738 | cell cortex region(GO:0099738) |
0.0 | 0.8 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.0 | 1.0 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 1.1 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 0.8 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 0.3 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.2 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 3.1 | GO:0030017 | sarcomere(GO:0030017) |
0.0 | 0.4 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.6 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 1.1 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 1.5 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.1 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 2.6 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.1 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 0.9 | GO:0005901 | caveola(GO:0005901) |
0.0 | 4.9 | GO:0043025 | neuronal cell body(GO:0043025) |
0.0 | 13.2 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
0.0 | 0.2 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 0.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.1 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.3 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.4 | GO:0043195 | terminal bouton(GO:0043195) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 10.5 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
1.1 | 3.3 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
0.8 | 3.2 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
0.7 | 2.2 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.7 | 4.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.7 | 3.3 | GO:0015265 | urea channel activity(GO:0015265) |
0.6 | 1.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.5 | 3.0 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.4 | 1.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.4 | 1.9 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.3 | 1.0 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.3 | 1.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.3 | 2.2 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.3 | 1.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.2 | 1.7 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.2 | 1.4 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.2 | 3.6 | GO:0003680 | AT DNA binding(GO:0003680) |
0.2 | 6.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.2 | 3.0 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.2 | 0.5 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.2 | 1.7 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.1 | 5.0 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 1.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 0.4 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.1 | 3.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.8 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.1 | 2.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 0.8 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.1 | 0.8 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.1 | 0.9 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 0.5 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.1 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
0.1 | 1.1 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.1 | 0.7 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 2.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 5.3 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 2.0 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 2.8 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 0.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.1 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 1.0 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 0.4 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.1 | 1.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.1 | 0.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 2.6 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.8 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 0.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 1.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.8 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 2.7 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.8 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 0.5 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 4.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.5 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.0 | 0.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.4 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.1 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 1.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 1.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.9 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.0 | 1.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 6.8 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 1.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 2.6 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.0 | 0.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 1.6 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.6 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.2 | 4.7 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.1 | 6.3 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 1.7 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.1 | 3.0 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.1 | 3.7 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.1 | 2.9 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.1 | 1.1 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.1 | 3.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 1.5 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.1 | 2.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.1 | 1.7 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 1.7 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 2.6 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 0.6 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.5 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 0.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.3 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.0 | 1.7 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.8 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.7 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.0 | 0.6 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 0.8 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 1.0 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 1.0 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 0.3 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.0 | 1.5 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 10.5 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
1.1 | 4.3 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.2 | 3.0 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.2 | 4.6 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.2 | 3.3 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.2 | 3.0 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.2 | 1.6 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.2 | 5.8 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 3.4 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.1 | 1.3 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 1.9 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.1 | 1.5 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 2.9 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.1 | 1.3 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.1 | 2.2 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.1 | 4.1 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 1.6 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 1.7 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
0.0 | 1.2 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 1.1 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 1.4 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 0.8 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 1.0 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 1.5 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 0.5 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 0.2 | REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL | Genes involved in NF-kB is activated and signals survival |
0.0 | 0.8 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.1 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 2.6 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.4 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.0 | 0.3 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.5 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |