Motif ID: Vdr
Z-value: 0.997

Transcription factors associated with Vdr:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Vdr | ENSMUSG00000022479.9 | Vdr |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
0.8 | 3.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.7 | 3.6 | GO:0070459 | prolactin secretion(GO:0070459) |
0.5 | 2.3 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
0.4 | 1.1 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.4 | 1.1 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.4 | 1.5 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.4 | 2.1 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
0.3 | 1.0 | GO:1902022 | L-lysine transport(GO:1902022) |
0.3 | 0.9 | GO:0016056 | photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
0.3 | 0.8 | GO:1902460 | transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.3 | 0.8 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.2 | 0.7 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.2 | 2.5 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.2 | 0.4 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
0.2 | 0.6 | GO:0015817 | histidine transport(GO:0015817) |
0.1 | 1.1 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.1 | 0.7 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
0.1 | 0.4 | GO:1904956 | regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
0.1 | 1.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 1.1 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 0.3 | GO:0006533 | aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416) |
0.1 | 1.5 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
0.1 | 0.3 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.1 | 0.4 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
0.1 | 0.5 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
0.1 | 0.6 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
0.1 | 0.2 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.1 | 0.8 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.1 | 0.4 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.1 | 0.2 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) |
0.1 | 0.2 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.1 | 1.2 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.1 | 0.6 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.1 | 0.3 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.1 | 0.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.1 | 0.3 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.1 | 0.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.1 | 0.9 | GO:0060134 | prepulse inhibition(GO:0060134) |
0.1 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
0.1 | 0.2 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) |
0.1 | 0.4 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.0 | 0.2 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.0 | 0.2 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.0 | 0.4 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
0.0 | 0.1 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
0.0 | 0.5 | GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) |
0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.1 | GO:0071105 | response to interleukin-11(GO:0071105) |
0.0 | 0.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.0 | 1.8 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 0.3 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.0 | 1.0 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 0.4 | GO:0060055 | angiogenesis involved in wound healing(GO:0060055) |
0.0 | 0.1 | GO:0070269 | pyroptosis(GO:0070269) |
0.0 | 0.3 | GO:0033622 | integrin activation(GO:0033622) |
0.0 | 0.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.1 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.0 | 0.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.0 | 0.1 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
0.0 | 1.2 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.0 | 1.0 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.0 | 0.4 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
0.0 | 0.4 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.4 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.1 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.0 | 0.1 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.8 | GO:0030819 | positive regulation of cAMP biosynthetic process(GO:0030819) |
0.0 | 0.1 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.0 | 0.1 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
0.0 | 0.1 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 0.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.2 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
0.0 | 0.1 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.6 | GO:0097487 | vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487) |
0.8 | 2.3 | GO:0098855 | HCN channel complex(GO:0098855) |
0.5 | 2.4 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.2 | 0.7 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
0.1 | 1.2 | GO:0036157 | outer dynein arm(GO:0036157) |
0.1 | 0.5 | GO:0098888 | extrinsic component of presynaptic membrane(GO:0098888) |
0.1 | 1.1 | GO:0044327 | dendritic spine head(GO:0044327) |
0.1 | 1.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 0.2 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.1 | 0.4 | GO:0070820 | tertiary granule(GO:0070820) |
0.1 | 1.0 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 1.2 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 0.2 | GO:0014802 | terminal cisterna(GO:0014802) |
0.1 | 0.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.5 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.0 | 0.7 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.3 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.6 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 1.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.1 | GO:0061702 | inflammasome complex(GO:0061702) |
0.0 | 0.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.1 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.0 | 0.3 | GO:0043203 | axon hillock(GO:0043203) |
0.0 | 0.1 | GO:0045160 | myosin I complex(GO:0045160) |
0.0 | 2.1 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.7 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.1 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.0 | 0.6 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 1.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.1 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 0.1 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 1.3 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.1 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.0 | 1.2 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.0 | GO:0042613 | MHC class II protein complex(GO:0042613) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.6 | 2.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.4 | 2.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.4 | 1.1 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.3 | 1.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.3 | 0.8 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.2 | 1.0 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.2 | 0.9 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.2 | 0.6 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
0.2 | 1.5 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.2 | 2.1 | GO:0038191 | neuropilin binding(GO:0038191) |
0.2 | 0.9 | GO:0016936 | galactoside binding(GO:0016936) |
0.1 | 0.9 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.1 | 0.6 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.1 | 0.4 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.1 | 0.3 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.1 | 0.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.1 | 0.8 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 0.3 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.1 | 1.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 1.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.3 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
0.1 | 1.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.1 | 2.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.2 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.1 | 0.2 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.1 | 0.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.1 | 0.2 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.1 | 1.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 0.9 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 0.3 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.1 | 0.2 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
0.1 | 0.2 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.1 | 0.2 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
0.0 | 0.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 1.8 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 0.1 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.0 | 0.4 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.0 | 0.1 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.0 | 0.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.6 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.8 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.5 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.0 | 0.5 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.0 | 0.2 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.1 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.1 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.0 | 0.3 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
0.0 | 0.8 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 1.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.1 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.0 | 0.3 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.6 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.6 | GO:0004601 | peroxidase activity(GO:0004601) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.6 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.1 | 0.9 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.1 | 1.5 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 1.7 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.8 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 3.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.6 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.0 | 1.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.2 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 1.8 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.4 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.0 | 0.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.6 | PID_FOXO_PATHWAY | FoxO family signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.1 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.2 | 3.6 | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | Genes involved in SHC1 events in EGFR signaling |
0.2 | 1.1 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 1.7 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.1 | 0.3 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.1 | 2.2 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.1 | 0.3 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.0 | 1.2 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 1.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.4 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.0 | 0.2 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.0 | 2.3 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.0 | 0.9 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.5 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.0 | 0.4 | REACTOME_IL_3_5_AND_GM_CSF_SIGNALING | Genes involved in Interleukin-3, 5 and GM-CSF signaling |
0.0 | 0.7 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.3 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |