Motif ID: Dlx1
Z-value: 1.065

Transcription factors associated with Dlx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dlx1 | ENSMUSG00000041911.3 | Dlx1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dlx1 | mm10_v2_chr2_+_71529085_71529110 | 0.21 | 4.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.8 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.4 | 1.2 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.4 | 1.2 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.3 | 1.3 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
0.3 | 1.3 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.3 | 1.5 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.2 | 3.0 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 0.9 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.2 | 1.1 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
0.2 | 0.6 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.2 | 0.8 | GO:0061743 | motor learning(GO:0061743) |
0.2 | 1.3 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.2 | 0.5 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.2 | 0.7 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.2 | 0.5 | GO:0019085 | early viral transcription(GO:0019085) |
0.1 | 0.4 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
0.1 | 0.8 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.1 | 0.6 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.1 | 1.0 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.1 | 0.4 | GO:0009838 | abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.1 | 0.6 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.1 | 0.5 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
0.1 | 0.3 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.1 | 0.7 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.1 | 0.8 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.1 | 1.5 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.3 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.1 | 0.7 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.1 | 0.3 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.1 | 0.6 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.1 | 0.5 | GO:0072235 | distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) |
0.1 | 0.9 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.1 | 0.4 | GO:0072592 | oxygen metabolic process(GO:0072592) |
0.1 | 0.9 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 0.3 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.1 | 0.4 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.1 | 0.3 | GO:0031038 | myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) |
0.1 | 0.3 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898) |
0.1 | 0.2 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.1 | 0.3 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.1 | 0.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
0.1 | 0.3 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.1 | 0.5 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.1 | 0.2 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
0.1 | 0.6 | GO:0046541 | saliva secretion(GO:0046541) |
0.1 | 1.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.1 | 0.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805) |
0.1 | 0.2 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.1 | 0.4 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
0.1 | 0.3 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.1 | 0.5 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 0.2 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.1 | 0.2 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
0.1 | 1.0 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.1 | 0.2 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
0.1 | 0.3 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.0 | 0.3 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
0.0 | 0.5 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.1 | GO:0007525 | somatic muscle development(GO:0007525) |
0.0 | 0.1 | GO:0002554 | serotonin secretion by platelet(GO:0002554) |
0.0 | 2.0 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 0.1 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.0 | 0.2 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.0 | 0.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.0 | 0.1 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
0.0 | 0.3 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.0 | 0.4 | GO:0036376 | sodium ion export from cell(GO:0036376) |
0.0 | 0.9 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.0 | 0.1 | GO:0006097 | glyoxylate cycle(GO:0006097) |
0.0 | 0.3 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.0 | 0.3 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.1 | GO:0045575 | basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575) |
0.0 | 0.1 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.0 | 0.2 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.0 | 0.4 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
0.0 | 0.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.1 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
0.0 | 0.1 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
0.0 | 0.3 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.6 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.1 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.0 | 0.1 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.0 | 0.3 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.3 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.0 | 0.1 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.0 | 0.2 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.2 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
0.0 | 0.1 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
0.0 | 0.9 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.5 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.0 | 0.1 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.0 | 1.1 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 1.4 | GO:0021884 | forebrain neuron development(GO:0021884) |
0.0 | 1.7 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.0 | 1.1 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 0.1 | GO:0006681 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
0.0 | 0.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.2 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.0 | 0.3 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 0.1 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.0 | 0.6 | GO:0097178 | ruffle assembly(GO:0097178) |
0.0 | 1.4 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.0 | 0.2 | GO:0032570 | response to progesterone(GO:0032570) |
0.0 | 0.1 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.0 | 0.1 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.0 | 0.1 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.0 | 0.6 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.1 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.0 | 0.4 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.0 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
0.0 | 0.1 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.0 | 0.1 | GO:0030223 | neutrophil differentiation(GO:0030223) |
0.0 | 1.6 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
0.0 | 0.0 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.0 | 0.5 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.1 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.2 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 0.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.0 | 0.3 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 0.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.2 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.4 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
0.2 | 1.4 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.2 | 0.8 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.2 | 0.9 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.1 | 3.0 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 1.6 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 1.7 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 0.6 | GO:0097443 | sorting endosome(GO:0097443) |
0.1 | 0.9 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 0.6 | GO:0033269 | internode region of axon(GO:0033269) |
0.1 | 0.3 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.1 | 0.3 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 0.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.0 | 0.2 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.0 | 0.6 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.5 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.0 | 0.4 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 0.1 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
0.0 | 0.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.0 | 1.5 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 1.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.9 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.2 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.1 | GO:0097637 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
0.0 | 0.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.0 | 1.2 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.7 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.2 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.0 | 1.1 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.1 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 0.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.6 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.1 | GO:0001739 | sex chromatin(GO:0001739) |
0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 1.4 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.1 | GO:0000812 | Swr1 complex(GO:0000812) |
0.0 | 2.2 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.2 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 1.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.7 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 0.1 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.3 | 1.2 | GO:0030151 | molybdenum ion binding(GO:0030151) |
0.3 | 1.7 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.3 | 0.8 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.3 | 0.8 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.2 | 0.9 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.2 | 1.0 | GO:0070330 | aromatase activity(GO:0070330) |
0.2 | 0.6 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.2 | 0.9 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.2 | 0.5 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.2 | 0.5 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.2 | 1.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 1.2 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.1 | 1.1 | GO:0005283 | sodium:amino acid symporter activity(GO:0005283) |
0.1 | 2.0 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.1 | 0.1 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.1 | 3.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 0.5 | GO:1904315 | GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.1 | 0.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.3 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.5 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 0.5 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.1 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.1 | 0.3 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
0.1 | 0.7 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 0.7 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.1 | 0.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 0.2 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.1 | 0.2 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
0.1 | 0.2 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.1 | 0.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 0.6 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.0 | 1.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 0.2 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.0 | 0.2 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
0.0 | 0.4 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.0 | 0.1 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
0.0 | 0.2 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 0.1 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.7 | GO:0042287 | MHC protein binding(GO:0042287) |
0.0 | 1.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.1 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.0 | 0.1 | GO:0016934 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
0.0 | 0.2 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.0 | 0.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.3 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 1.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.6 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.0 | 0.1 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.0 | 0.2 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 0.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.1 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.0 | 0.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.0 | 0.2 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.2 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.0 | 0.1 | GO:0009374 | biotin binding(GO:0009374) |
0.0 | 0.1 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.0 | 0.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.1 | GO:0089720 | caspase binding(GO:0089720) |
0.0 | 0.1 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.0 | 0.1 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
0.0 | 3.1 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.1 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 1.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 0.1 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.0 | 0.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.0 | 0.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.1 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.0 | 0.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.1 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.0 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | NABA_CORE_MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
0.0 | 1.5 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.4 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 1.1 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 0.9 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.0 | 0.6 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 0.2 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.4 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.1 | 1.1 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 0.9 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.1 | 1.6 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.1 | 2.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 3.0 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 1.5 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.1 | 1.0 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.0 | 1.0 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 0.6 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 0.3 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.5 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.0 | 0.3 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 1.0 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
0.0 | 0.3 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 0.7 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.0 | 0.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 0.6 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 1.0 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.3 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.0 | 0.6 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.3 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.1 | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
0.0 | 0.4 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 1.5 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.2 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.0 | 1.9 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 1.3 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | Genes involved in Transmission across Chemical Synapses |
0.0 | 0.4 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |