Motif ID: Zfp219_Zfp740
Z-value: 1.208


Transcription factors associated with Zfp219_Zfp740:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zfp219 | ENSMUSG00000049295.10 | Zfp219 |
Zfp740 | ENSMUSG00000046897.10 | Zfp740 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zfp740 | mm10_v2_chr15_+_102203639_102203709 | 0.66 | 3.0e-03 | Click! |
Zfp219 | mm10_v2_chr14_-_52020698_52020737 | -0.08 | 7.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 10.0 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
1.5 | 4.6 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
1.2 | 3.5 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
1.1 | 4.6 | GO:1904048 | regulation of spontaneous neurotransmitter secretion(GO:1904048) |
1.0 | 5.0 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.7 | 2.2 | GO:0060023 | soft palate development(GO:0060023) |
0.7 | 2.9 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
0.6 | 4.5 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.6 | 1.9 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
0.5 | 3.1 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.5 | 1.5 | GO:0014916 | regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793) |
0.4 | 3.9 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.4 | 6.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.4 | 1.3 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.4 | 1.2 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.4 | 2.5 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.4 | 2.0 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.4 | 0.4 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.4 | 1.6 | GO:0060032 | notochord regression(GO:0060032) |
0.4 | 3.0 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.4 | 1.1 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.4 | 3.9 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.3 | 1.4 | GO:0045358 | negative regulation of interferon-beta biosynthetic process(GO:0045358) |
0.3 | 1.7 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.3 | 0.7 | GO:0097117 | guanylate kinase-associated protein clustering(GO:0097117) |
0.3 | 1.0 | GO:0097402 | neuroblast migration(GO:0097402) |
0.3 | 1.5 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.3 | 1.2 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
0.3 | 1.2 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.3 | 0.9 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
0.3 | 0.8 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.3 | 1.0 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.3 | 2.8 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.2 | 1.0 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
0.2 | 3.9 | GO:1990403 | embryonic brain development(GO:1990403) |
0.2 | 0.7 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
0.2 | 0.7 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
0.2 | 0.5 | GO:0021759 | globus pallidus development(GO:0021759) |
0.2 | 1.3 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.2 | 0.6 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.2 | 0.8 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
0.2 | 1.2 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.2 | 0.8 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
0.2 | 2.0 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.2 | 1.5 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.2 | 1.7 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
0.2 | 0.6 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
0.2 | 0.6 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.2 | 1.3 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.2 | 0.5 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
0.2 | 0.5 | GO:0010752 | negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) |
0.2 | 0.7 | GO:0097393 | post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582) |
0.2 | 0.3 | GO:0046881 | positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
0.2 | 4.1 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.2 | 0.9 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.2 | 0.5 | GO:0070602 | regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602) |
0.2 | 1.1 | GO:0070814 | hydrogen sulfide biosynthetic process(GO:0070814) |
0.1 | 0.1 | GO:0043585 | nose morphogenesis(GO:0043585) |
0.1 | 0.6 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
0.1 | 0.3 | GO:0071286 | cellular response to magnesium ion(GO:0071286) |
0.1 | 0.8 | GO:0072718 | response to cisplatin(GO:0072718) |
0.1 | 1.1 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.1 | 1.4 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
0.1 | 0.5 | GO:1904398 | positive regulation of neuromuscular junction development(GO:1904398) |
0.1 | 0.4 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.1 | 1.9 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 1.2 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.5 | GO:0052151 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
0.1 | 0.5 | GO:0097494 | regulation of vesicle size(GO:0097494) |
0.1 | 0.3 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
0.1 | 0.8 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
0.1 | 0.1 | GO:2000830 | vacuolar phosphate transport(GO:0007037) vitamin D3 metabolic process(GO:0070640) positive regulation of parathyroid hormone secretion(GO:2000830) |
0.1 | 0.6 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
0.1 | 1.2 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
0.1 | 1.0 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.1 | 0.5 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
0.1 | 0.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 0.4 | GO:0060437 | lung growth(GO:0060437) |
0.1 | 2.1 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
0.1 | 0.6 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.1 | 0.8 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.1 | 0.4 | GO:0061010 | gall bladder development(GO:0061010) |
0.1 | 0.6 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 0.4 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.1 | 1.7 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.1 | 0.3 | GO:0014735 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) regulation of muscle atrophy(GO:0014735) |
0.1 | 0.9 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.1 | 0.3 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.1 | 0.3 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.1 | 0.6 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.1 | 0.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 0.8 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 0.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.1 | 1.3 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
0.1 | 0.1 | GO:1902661 | regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661) |
0.1 | 1.5 | GO:0099612 | protein localization to axon(GO:0099612) |
0.1 | 2.5 | GO:0007520 | myoblast fusion(GO:0007520) |
0.1 | 0.6 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) |
0.1 | 0.1 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.1 | 0.6 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.1 | 0.6 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.1 | 0.5 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
0.1 | 0.7 | GO:0046959 | habituation(GO:0046959) |
0.1 | 0.8 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
0.1 | 0.3 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.1 | 1.0 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 2.5 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.1 | 0.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.1 | 0.4 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.1 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
0.1 | 0.2 | GO:0097298 | regulation of nucleus size(GO:0097298) |
0.1 | 0.5 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 0.2 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.1 | 0.1 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
0.1 | 0.3 | GO:0060982 | coronary artery morphogenesis(GO:0060982) |
0.1 | 0.5 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.1 | 2.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 0.5 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.1 | 0.3 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
0.1 | 2.1 | GO:0009994 | oocyte differentiation(GO:0009994) |
0.1 | 0.4 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
0.1 | 0.4 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.1 | 0.9 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.3 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.1 | 0.7 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.0 | 0.5 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 0.5 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.0 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.0 | 0.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.0 | 0.1 | GO:0072553 | terminal button organization(GO:0072553) |
0.0 | 0.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.0 | 0.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 2.2 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.0 | 0.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.1 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
0.0 | 0.2 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
0.0 | 0.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.0 | 0.2 | GO:0010642 | negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642) |
0.0 | 0.5 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.0 | 0.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.1 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
0.0 | 0.4 | GO:0055090 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
0.0 | 0.3 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.0 | 0.2 | GO:0097646 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.0 | 0.2 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
0.0 | 0.9 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:1904017 | positive regulation of female receptivity(GO:0045925) response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
0.0 | 0.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.5 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.6 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.3 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
0.0 | 0.7 | GO:0048169 | regulation of long-term neuronal synaptic plasticity(GO:0048169) |
0.0 | 0.5 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.1 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.0 | 0.6 | GO:0007143 | female meiotic division(GO:0007143) |
0.0 | 0.3 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
0.0 | 0.6 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.6 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.1 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.0 | 0.5 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.2 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
0.0 | 0.6 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 1.9 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.4 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 1.1 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
0.0 | 0.1 | GO:0009405 | pathogenesis(GO:0009405) |
0.0 | 0.1 | GO:0071579 | regulation of zinc ion transport(GO:0071579) |
0.0 | 0.1 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.0 | 0.2 | GO:0051014 | actin filament severing(GO:0051014) |
0.0 | 0.1 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
0.0 | 0.4 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.0 | 0.3 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.2 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.0 | 0.2 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
0.0 | 0.8 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
0.0 | 0.2 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 0.7 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.0 | 0.6 | GO:0001755 | neural crest cell migration(GO:0001755) |
0.0 | 0.2 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
0.0 | 0.1 | GO:0000733 | DNA strand renaturation(GO:0000733) |
0.0 | 0.1 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 0.4 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.0 | 2.2 | GO:0007051 | spindle organization(GO:0007051) |
0.0 | 0.1 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.1 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.0 | 0.2 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.2 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
0.0 | 0.4 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
0.0 | 0.4 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 0.9 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
0.0 | 0.5 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
0.0 | 1.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.1 | GO:0051775 | response to redox state(GO:0051775) |
0.0 | 0.6 | GO:0009612 | response to mechanical stimulus(GO:0009612) |
0.0 | 0.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 0.1 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.0 | 0.1 | GO:0032484 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
0.0 | 0.7 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
0.0 | 0.2 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.0 | GO:1990859 | cellular response to endothelin(GO:1990859) |
0.0 | 0.1 | GO:0014052 | regulation of gamma-aminobutyric acid secretion(GO:0014052) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.6 | 1.7 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
0.5 | 2.5 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.4 | 1.5 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.3 | 1.0 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.3 | 0.8 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
0.3 | 6.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.2 | 3.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.2 | 1.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.2 | 3.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.2 | 3.8 | GO:0010369 | chromocenter(GO:0010369) |
0.2 | 1.9 | GO:0032584 | growth cone membrane(GO:0032584) |
0.2 | 0.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.2 | 0.7 | GO:1990421 | subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707) |
0.2 | 2.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.2 | 1.5 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 0.6 | GO:0043259 | laminin-10 complex(GO:0043259) |
0.1 | 0.8 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.1 | 11.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.1 | 1.6 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 1.6 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 0.8 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 0.6 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.1 | 0.8 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 2.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.1 | 0.6 | GO:0044305 | calyx of Held(GO:0044305) |
0.1 | 0.9 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.1 | 1.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 2.8 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 3.9 | GO:0035869 | ciliary transition zone(GO:0035869) |
0.1 | 1.0 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.1 | 0.9 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.1 | 0.3 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.1 | 0.9 | GO:0031011 | Ino80 complex(GO:0031011) |
0.1 | 1.2 | GO:0045180 | basal cortex(GO:0045180) |
0.1 | 0.3 | GO:0043511 | inhibin complex(GO:0043511) |
0.1 | 0.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 6.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 0.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 0.2 | GO:0034679 | integrin alpha9-beta1 complex(GO:0034679) |
0.1 | 0.6 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 2.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.1 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
0.1 | 0.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.1 | 0.6 | GO:0044327 | dendritic spine head(GO:0044327) |
0.1 | 2.2 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 6.0 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 0.3 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.1 | 0.6 | GO:0031010 | ISWI-type complex(GO:0031010) |
0.1 | 0.2 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
0.1 | 0.4 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.1 | 0.6 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.0 | 1.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.5 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.2 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
0.0 | 1.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.3 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 1.4 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 1.9 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.3 | GO:0070578 | micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578) |
0.0 | 0.5 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 0.5 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 5.4 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.2 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.0 | 1.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.3 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 0.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.8 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 0.3 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.5 | GO:0098839 | postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634) |
0.0 | 0.1 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
0.0 | 0.2 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 0.6 | GO:0032590 | dendrite membrane(GO:0032590) |
0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.7 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.2 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 0.3 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.5 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.5 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.0 | 2.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.4 | GO:0000791 | euchromatin(GO:0000791) |
0.0 | 0.2 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.2 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 0.1 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.0 | 1.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 2.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 0.4 | GO:0030118 | clathrin coat(GO:0030118) |
0.0 | 0.1 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.2 | GO:0005844 | polysome(GO:0005844) |
0.0 | 2.5 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 0.3 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.0 | 0.2 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 1.3 | GO:0044306 | neuron projection terminus(GO:0044306) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.3 | 10.0 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
1.1 | 4.5 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.9 | 4.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.8 | 3.9 | GO:1990188 | euchromatin binding(GO:1990188) |
0.5 | 2.7 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.4 | 1.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.4 | 5.0 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.3 | 1.3 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.3 | 2.6 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.3 | 2.6 | GO:0001093 | TFIIB-class transcription factor binding(GO:0001093) |
0.3 | 1.9 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.3 | 1.2 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.3 | 2.4 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.3 | 1.5 | GO:0097001 | ceramide binding(GO:0097001) |
0.2 | 1.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.2 | 2.8 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.2 | 1.5 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.2 | 3.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.2 | 1.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.2 | 0.5 | GO:0070052 | collagen V binding(GO:0070052) |
0.2 | 1.3 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) |
0.1 | 1.0 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 1.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.1 | 0.4 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 0.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 0.9 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 0.4 | GO:0016901 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
0.1 | 1.0 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.1 | 0.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 0.7 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.1 | 0.5 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 0.9 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.1 | 3.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.5 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.1 | 2.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 1.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 1.2 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
0.1 | 0.8 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 0.6 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 0.9 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.1 | 0.4 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
0.1 | 2.0 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 0.3 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
0.1 | 0.8 | GO:0039706 | co-receptor binding(GO:0039706) |
0.1 | 0.6 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.3 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.1 | 0.7 | GO:0048495 | Roundabout binding(GO:0048495) |
0.1 | 0.3 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.1 | 0.8 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.1 | 0.7 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.1 | 1.9 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 0.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.1 | 0.2 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
0.1 | 0.6 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.1 | 0.3 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.1 | 2.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 0.3 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.1 | 0.4 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.1 | 0.3 | GO:0050436 | microfibril binding(GO:0050436) |
0.1 | 0.4 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.1 | 0.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.2 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 0.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.5 | GO:0034046 | poly(G) binding(GO:0034046) |
0.1 | 0.5 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.1 | 0.5 | GO:0019534 | toxin transporter activity(GO:0019534) |
0.1 | 0.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.1 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.1 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.0 | 0.3 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 0.2 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.0 | 0.2 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
0.0 | 0.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 1.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.2 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
0.0 | 0.1 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.0 | 0.3 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.7 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.7 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.6 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
0.0 | 1.3 | GO:0001221 | transcription cofactor binding(GO:0001221) |
0.0 | 0.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.2 | GO:0032451 | demethylase activity(GO:0032451) histone demethylase activity(GO:0032452) |
0.0 | 0.2 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.0 | 1.6 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 1.1 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.7 | GO:0043274 | phospholipase binding(GO:0043274) |
0.0 | 0.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.1 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
0.0 | 0.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.0 | 1.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 1.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 0.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.0 | 0.4 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.0 | 0.1 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.0 | 1.3 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.1 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.0 | 0.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 1.0 | GO:0003678 | DNA helicase activity(GO:0003678) |
0.0 | 1.1 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 2.4 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.1 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
0.0 | 1.8 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.4 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 5.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.8 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.0 | 0.2 | GO:0070840 | dynein complex binding(GO:0070840) |
0.0 | 0.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 1.6 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.0 | 0.1 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.4 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.1 | GO:0031005 | filamin binding(GO:0031005) |
0.0 | 0.1 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.0 | 0.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.0 | 0.2 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.0 | 0.7 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.5 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 2.9 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 9.7 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.1 | 1.5 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 0.9 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 0.3 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.1 | 0.8 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.1 | 2.6 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 2.0 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.1 | 0.8 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 3.4 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.1 | 0.9 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.1 | 4.4 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.1 | 0.5 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.1 | 2.0 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 3.8 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.1 | 3.1 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.7 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 3.9 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 2.7 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 0.9 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.0 | 2.9 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.8 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 0.5 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.9 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.5 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 0.8 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.0 | 0.2 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.0 | 0.5 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
0.0 | 0.1 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.4 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 1.2 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 0.0 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.0 | 0.4 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.9 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.5 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.8 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.9 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
0.1 | 3.7 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.1 | 2.0 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 1.2 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.1 | 0.7 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 0.3 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.1 | 2.0 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.1 | 2.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 0.8 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.1 | 1.4 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.1 | 0.9 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
0.1 | 1.4 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 0.9 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.0 | 0.5 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.5 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 0.4 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.0 | 0.4 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.7 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 0.9 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
0.0 | 2.8 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.3 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.0 | 1.1 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.3 | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
0.0 | 0.9 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
0.0 | 0.3 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.8 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.1 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
0.0 | 0.2 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.5 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 1.3 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.2 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
0.0 | 0.4 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 1.5 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.1 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 1.0 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.3 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.2 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |