Motif ID: Hmga1

Z-value: 0.987


Transcription factors associated with Hmga1:

Gene SymbolEntrez IDGene Name
Hmga1 ENSMUSG00000046711.9 Hmga1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556668_275566900.653.5e-03Click!


Activity profile for motif Hmga1.

activity profile for motif Hmga1


Sorted Z-values histogram for motif Hmga1

Sorted Z-values for motif Hmga1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 8.216 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr18_+_20665250 7.876 ENSMUST00000075312.3
Ttr
transthyretin
chr14_-_48667508 2.859 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr17_+_85620816 2.758 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr3_+_102010138 2.362 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr8_-_87959560 2.334 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr1_+_45311538 2.147 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr16_-_26989974 2.051 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr17_+_43953191 2.011 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr10_+_4611971 1.786 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr10_+_97482350 1.547 ENSMUST00000163448.2
Dcn
decorin
chr17_+_43952999 1.514 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr3_-_88577208 1.418 ENSMUST00000098952.2
Gm10704
predicted pseudogene 10704
chr10_-_92165159 1.377 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr9_-_100506844 1.377 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr10_+_97565436 1.371 ENSMUST00000038160.4
Lum
lumican
chr12_-_108003594 1.359 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr3_-_10208569 1.345 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr1_+_107511416 1.281 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr10_+_96136603 1.271 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr4_-_36056726 1.266 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr4_-_97584605 1.257 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr18_+_35770318 1.253 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr14_+_26514554 1.184 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr6_-_25690729 1.152 ENSMUST00000054867.6
Gpr37
G protein-coupled receptor 37
chr17_+_28692568 1.143 ENSMUST00000114752.1
Mapk14
mitogen-activated protein kinase 14
chr15_-_56694525 1.086 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr19_+_24875679 1.085 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr15_+_34238026 1.068 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr10_+_88091070 1.033 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr7_-_143460989 1.019 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr15_+_79030874 1.011 ENSMUST00000171999.1
ENSMUST00000006544.7
Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

chr3_+_67892189 1.005 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr3_+_134236483 0.993 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr10_+_102158858 0.992 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr2_+_125866107 0.979 ENSMUST00000134337.1
ENSMUST00000094604.2
ENSMUST00000134798.1
Galk2


galactokinase 2


chr10_-_33624587 0.978 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr10_+_11609256 0.977 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr10_+_53596936 0.969 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr16_-_59632520 0.968 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr1_-_158814469 0.967 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr7_-_139582790 0.914 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr7_-_84679346 0.913 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr19_-_24861828 0.896 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr4_-_97584612 0.886 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_+_67647405 0.883 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr10_-_35711891 0.784 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr3_-_150073620 0.761 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr6_+_88724828 0.747 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr2_-_79908389 0.715 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr19_+_9283231 0.712 ENSMUST00000088040.4
Pcna-ps2
proliferating cell nuclear antigen pseudogene 2
chr13_-_56895737 0.707 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr4_+_101507947 0.704 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_109676568 0.697 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr1_+_45981548 0.691 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr14_-_46788267 0.686 ENSMUST00000015903.4
Cnih1
cornichon homolog 1 (Drosophila)
chr4_+_105789869 0.684 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr7_+_46847128 0.682 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr4_-_92191749 0.675 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr2_-_140671462 0.674 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr7_-_28302238 0.667 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr9_+_57521232 0.659 ENSMUST00000000090.6
Cox5a
cytochrome c oxidase subunit Va
chrX_-_23285532 0.657 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr12_-_10900296 0.652 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr11_-_82829024 0.649 ENSMUST00000021036.6
ENSMUST00000074515.4
ENSMUST00000103218.2
Rffl


ring finger and FYVE like domain containing protein


chr2_+_20737306 0.647 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr9_-_70421533 0.625 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr6_+_135065651 0.624 ENSMUST00000050104.7
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr4_+_105157339 0.623 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr15_+_44196135 0.618 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr15_+_31276491 0.614 ENSMUST00000068987.5
Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr2_-_69206146 0.609 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chrX_-_163761323 0.604 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr1_+_59482133 0.599 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr14_+_105681824 0.594 ENSMUST00000073238.6
Gm10076
predicted gene 10076
chr10_+_96616998 0.594 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr2_-_164389095 0.584 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr4_-_40279389 0.575 ENSMUST00000108108.2
ENSMUST00000095128.3
Ndufb6

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6

chr1_+_109993982 0.567 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr19_-_32466575 0.562 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr1_-_89933290 0.548 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr3_+_106034661 0.545 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr11_+_101627942 0.537 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr18_-_62741387 0.533 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr2_-_69206133 0.519 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr15_-_36598019 0.515 ENSMUST00000155116.1
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr6_-_99028874 0.503 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr13_-_18031616 0.501 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr12_+_100110148 0.497 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr7_-_126704816 0.496 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr2_+_130277157 0.495 ENSMUST00000028890.8
ENSMUST00000159373.1
Nop56

NOP56 ribonucleoprotein

chr2_-_140671400 0.494 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr5_+_124579134 0.483 ENSMUST00000031333.3
Gtf2h3
general transcription factor IIH, polypeptide 3
chr15_+_82345954 0.482 ENSMUST00000023086.8
Smdt1
single-pass membrane protein with aspartate rich tail 1
chr8_-_111854278 0.479 ENSMUST00000034432.5
Cfdp1
craniofacial development protein 1
chr11_+_6415443 0.479 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr17_-_24073479 0.474 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr2_+_14388434 0.474 ENSMUST00000133258.1
Slc39a12
solute carrier family 39 (zinc transporter), member 12
chr5_-_88527841 0.473 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr6_-_125191535 0.471 ENSMUST00000043848.4
Ncapd2
non-SMC condensin I complex, subunit D2
chrX_-_17571563 0.471 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chr11_+_22512088 0.470 ENSMUST00000059319.7
Tmem17
transmembrane protein 17
chr7_-_113347273 0.464 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr1_-_171150588 0.463 ENSMUST00000155798.1
ENSMUST00000081560.4
ENSMUST00000111336.3
Sdhc


succinate dehydrogenase complex, subunit C, integral membrane protein


chr1_-_140183283 0.455 ENSMUST00000111977.1
Cfh
complement component factor h
chr18_-_36726730 0.455 ENSMUST00000061829.6
Cd14
CD14 antigen
chr13_-_114388057 0.448 ENSMUST00000022286.6
Ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4
chr11_-_98625661 0.444 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr14_-_52104015 0.443 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr7_+_67655414 0.442 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr14_+_113314602 0.436 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr9_+_65890237 0.435 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr18_+_11633276 0.434 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr5_+_8046077 0.427 ENSMUST00000088786.4
Sri
sorcin
chr7_-_126704736 0.425 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr1_-_52499980 0.423 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr4_-_123750236 0.420 ENSMUST00000102636.3
Akirin1
akirin 1
chr1_-_162898665 0.419 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr18_+_75000469 0.418 ENSMUST00000079716.5
Rpl17
ribosomal protein L17
chr11_-_107189325 0.401 ENSMUST00000018577.7
ENSMUST00000106757.1
Nol11

nucleolar protein 11

chr9_-_78489141 0.399 ENSMUST00000154207.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr19_-_37330613 0.392 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr8_+_45658731 0.387 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr15_+_99074968 0.381 ENSMUST00000039665.6
Troap
trophinin associated protein
chr8_+_45658666 0.378 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr6_-_136875794 0.373 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr6_-_30390997 0.372 ENSMUST00000152391.2
ENSMUST00000115184.1
ENSMUST00000080812.7
ENSMUST00000102992.3
Zc3hc1



zinc finger, C3HC type 1



chr11_+_108682602 0.370 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr7_-_60005101 0.369 ENSMUST00000059305.10
Snrpn
small nuclear ribonucleoprotein N
chr10_+_37139558 0.356 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr6_-_99044414 0.355 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr1_+_4808237 0.353 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr3_-_63851251 0.348 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr18_+_56562443 0.337 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax

phosphorylated adaptor for RNA export

chr15_-_99651580 0.337 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
Racgap1




Rac GTPase-activating protein 1




chr6_-_99435345 0.337 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
Foxp1


forkhead box P1


chr10_+_5593718 0.336 ENSMUST00000051809.8
Myct1
myc target 1
chr5_+_33018816 0.333 ENSMUST00000019109.7
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr12_-_65073927 0.332 ENSMUST00000021332.8
Fkbp3
FK506 binding protein 3
chr2_+_14388316 0.331 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr5_-_124579045 0.330 ENSMUST00000135361.1
ENSMUST00000031334.8
Eif2b1

eukaryotic translation initiation factor 2B, subunit 1 (alpha)

chr5_+_104046980 0.323 ENSMUST00000134313.1
Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr15_-_100424092 0.322 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr6_-_39810881 0.316 ENSMUST00000114797.1
ENSMUST00000031978.8
Mrps33

mitochondrial ribosomal protein S33

chr1_-_140183404 0.308 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr11_+_69395647 0.305 ENSMUST00000144531.1
Lsmd1
LSM domain containing 1
chr3_-_104864420 0.305 ENSMUST00000094028.5
Capza1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_-_44019929 0.287 ENSMUST00000061421.3
Mettl21c
methyltransferase like 21C
chr3_+_124321031 0.286 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr15_+_41447438 0.284 ENSMUST00000110297.2
ENSMUST00000090096.4
Oxr1

oxidation resistance 1

chr5_-_124578992 0.282 ENSMUST00000128920.1
Eif2b1
eukaryotic translation initiation factor 2B, subunit 1 (alpha)
chr6_-_13871459 0.279 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr15_+_99006056 0.272 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr2_-_21205342 0.269 ENSMUST00000027992.2
Enkur
enkurin, TRPC channel interacting protein
chr5_-_5266038 0.267 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr3_-_20242173 0.266 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr6_+_17636983 0.265 ENSMUST00000015877.7
Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chrX_-_136741155 0.262 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr3_+_97901190 0.261 ENSMUST00000029476.2
ENSMUST00000122288.1
Sec22b

SEC22 vesicle trafficking protein homolog B (S. cerevisiae)

chr19_-_47919269 0.252 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr4_+_21727726 0.252 ENSMUST00000102997.1
ENSMUST00000120679.1
ENSMUST00000108240.2
Ccnc


cyclin C


chr11_-_79962374 0.251 ENSMUST00000108241.1
ENSMUST00000043152.5
Utp6

UTP6, small subunit (SSU) processome component, homolog (yeast)

chr5_+_48242549 0.250 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr6_-_30693676 0.249 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr15_-_101054399 0.247 ENSMUST00000178140.1
Fignl2
fidgetin-like 2
chr2_-_51149100 0.242 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr13_+_21495218 0.240 ENSMUST00000104942.1
AK157302
cDNA sequence AK157302
chrX_-_59568068 0.237 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr16_-_57754707 0.236 ENSMUST00000089332.4
Col8a1
collagen, type VIII, alpha 1
chr16_+_20672716 0.233 ENSMUST00000044783.7
ENSMUST00000115463.1
ENSMUST00000142344.1
ENSMUST00000073840.5
ENSMUST00000140576.1
ENSMUST00000115457.1
Eif4g1





eukaryotic translation initiation factor 4, gamma 1





chrX_-_103483205 0.232 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr15_+_41830921 0.231 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chrX_+_159303266 0.229 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr12_+_72441933 0.225 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chrX_-_17572241 0.221 ENSMUST00000176638.1
ENSMUST00000026016.6
Fundc1

FUN14 domain containing 1

chrX_-_59567348 0.220 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chrY_+_13252442 0.218 ENSMUST00000178599.1
Gm21440
predicted gene, 21440
chrX_-_134751331 0.218 ENSMUST00000113194.1
ENSMUST00000052431.5
Armcx6

armadillo repeat containing, X-linked 6

chr7_-_62420139 0.217 ENSMUST00000094340.3
Mkrn3
makorin, ring finger protein, 3
chr4_+_123282778 0.203 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chrX_+_163911401 0.201 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr19_+_55742242 0.200 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr12_+_98771018 0.199 ENSMUST00000021399.7
Zc3h14
zinc finger CCCH type containing 14
chrX_+_75095854 0.194 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr6_-_13871477 0.192 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr6_-_102464667 0.189 ENSMUST00000032159.6
Cntn3
contactin 3
chr15_-_100424208 0.183 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_-_38019505 0.180 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr6_+_91684061 0.179 ENSMUST00000032185.7
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr3_-_108536466 0.177 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
5330417C22Rik


RIKEN cDNA 5330417C22 gene


chr10_-_34207551 0.175 ENSMUST00000048010.7
Dse
dermatan sulfate epimerase
chr2_-_140671440 0.175 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr14_+_74640840 0.171 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr3_-_121171678 0.170 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr8_-_36732897 0.167 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr15_-_103215285 0.165 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr11_+_110968056 0.164 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_+_85574109 0.164 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
Pet112


PET112 homolog (S. cerevisiae)


chr11_+_52232009 0.159 ENSMUST00000037324.5
ENSMUST00000166537.1
Skp1a

S-phase kinase-associated protein 1A

chr11_+_101582236 0.159 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
Tmem106a



transmembrane protein 106A




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 11.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.6 7.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.7 2.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.5 1.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.4 1.3 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 1.8 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.4 2.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.3 1.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 1.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 1.1 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 0.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 4.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 1.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 1.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0021546 rhombomere development(GO:0021546)
0.2 0.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 0.9 GO:0032796 uropod organization(GO:0032796)
0.1 0.6 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 1.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.7 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 1.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.7 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.9 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.8 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.1 1.2 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.5 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.3 GO:0051030 snRNA transport(GO:0051030)
0.1 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.3 GO:0046032 ADP catabolic process(GO:0046032)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 0.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.3 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 1.0 GO:0006012 galactose metabolic process(GO:0006012)
0.1 2.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.1 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.1 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 2.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.2 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069)
0.0 1.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0097274 urea homeostasis(GO:0097274)
0.0 0.1 GO:0060214 stem cell fate specification(GO:0048866) endocardium formation(GO:0060214) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.9 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280) negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 1.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.4 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.6 GO:0048538 thymus development(GO:0048538)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 3.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 1.1 GO:0031262 Ndc80 complex(GO:0031262)
0.2 0.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0000805 X chromosome(GO:0000805)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.4 GO:0045120 telomerase holoenzyme complex(GO:0005697) pronucleus(GO:0045120)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0070469 respiratory chain(GO:0070469)
0.0 1.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 2.8 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 3.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.0 GO:0004335 galactokinase activity(GO:0004335)
0.2 1.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.8 GO:0019808 polyamine binding(GO:0019808)
0.2 0.8 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.5 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 8.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.0 2.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 2.4 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 2.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID_GLYPICAN_1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 8.0 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 1.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.7 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.1 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.5 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.1 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.6 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_KINESINS Genes involved in Kinesins