Motif ID: Klf8

Z-value: 1.015


Transcription factors associated with Klf8:

Gene SymbolEntrez IDGene Name
Klf8 ENSMUSG00000041649.7 Klf8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf8mm10_v2_chrX_+_153359613_153359613-0.865.6e-06Click!


Activity profile for motif Klf8.

activity profile for motif Klf8


Sorted Z-values histogram for motif Klf8

Sorted Z-values for motif Klf8



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_70851189 5.757 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr19_+_25610533 3.856 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr7_-_127026479 3.855 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_-_72788952 3.808 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr3_+_87948666 3.285 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr4_+_46450892 2.230 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_172550991 2.156 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr3_+_94377432 2.146 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr4_-_97778042 2.133 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr9_-_8004585 1.966 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr2_+_165595009 1.963 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr7_-_30973464 1.933 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr13_+_48261427 1.869 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr3_+_94377505 1.775 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr16_+_30599717 1.763 ENSMUST00000059078.3
Fam43a
family with sequence similarity 43, member A
chr7_-_144939823 1.635 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr2_-_54085542 1.592 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr7_+_4119525 1.514 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr10_+_4710119 1.513 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr7_+_4119556 1.502 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr13_-_60177357 1.485 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr6_+_85187438 1.443 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chrX_+_71050160 1.441 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr14_-_8666236 1.405 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr3_+_146500071 1.373 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr17_-_70851710 1.372 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr19_+_6975048 1.332 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_27886416 1.321 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr3_+_146499828 1.302 ENSMUST00000090031.5
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr3_+_146499850 1.281 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chrX_-_51205990 1.271 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr8_-_87959560 1.264 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr15_+_39006272 1.259 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr3_-_89393294 1.216 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr15_-_75909543 1.190 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr11_+_69632927 1.185 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr1_+_92831614 1.170 ENSMUST00000045970.6
Gpc1
glypican 1
chr17_+_34898931 1.170 ENSMUST00000097342.3
ENSMUST00000013931.5
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr9_+_45138437 1.133 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr12_+_8771405 1.104 ENSMUST00000171158.1
Sdc1
syndecan 1
chr10_-_80399478 1.072 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr12_-_57546121 1.069 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr18_+_74442500 1.049 ENSMUST00000074157.6
Myo5b
myosin VB
chr3_+_87906321 1.044 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr5_-_114690974 1.029 ENSMUST00000012028.7
Gltp
glycolipid transfer protein
chr19_+_7268296 1.015 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr1_-_20820213 1.013 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr6_+_34354119 0.993 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr19_-_4615453 0.979 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr2_+_156840077 0.979 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr19_-_12765447 0.969 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr2_-_168590315 0.962 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr11_+_114765363 0.939 ENSMUST00000138804.1
ENSMUST00000084368.5
Kif19a

kinesin family member 19A

chr12_-_69228167 0.925 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr16_+_64851991 0.919 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr13_-_3918157 0.890 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr5_+_74195281 0.889 ENSMUST00000051937.7
Rasl11b
RAS-like, family 11, member B
chr12_+_8771317 0.885 ENSMUST00000020911.7
Sdc1
syndecan 1
chr2_-_30093642 0.883 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_+_70657687 0.880 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr17_+_34898463 0.833 ENSMUST00000114033.2
ENSMUST00000078061.6
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chrM_-_14060 0.821 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr12_+_109452833 0.820 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chrX_-_73921917 0.789 ENSMUST00000114389.3
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr4_-_155043143 0.775 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr4_-_136602641 0.774 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a

lysine (K)-specific demethylase 1A

chr16_-_18811615 0.770 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr2_-_65238625 0.768 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobll1


Cobl-like 1


chr14_+_65358661 0.764 ENSMUST00000066994.6
Zfp395
zinc finger protein 395
chr10_-_77089428 0.761 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr7_-_19399859 0.758 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr6_+_120666388 0.757 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr15_-_75909289 0.747 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr7_+_100495987 0.745 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_-_63938862 0.744 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr14_+_55854115 0.739 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr3_+_129213920 0.733 ENSMUST00000042587.10
Pitx2
paired-like homeodomain transcription factor 2
chr15_-_89373810 0.719 ENSMUST00000167643.2
Sco2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr15_-_75909319 0.719 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr2_-_30093607 0.708 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_-_101466222 0.701 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr4_+_41762309 0.677 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr4_-_57956283 0.676 ENSMUST00000030051.5
Txn1
thioredoxin 1
chr1_-_172027269 0.674 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr9_-_106158109 0.674 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr7_-_142657466 0.671 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr5_-_101665195 0.669 ENSMUST00000044125.8
Nkx6-1
NK6 homeobox 1
chrX_-_51205773 0.668 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr14_+_54476100 0.666 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr9_+_66158206 0.655 ENSMUST00000034944.2
Dapk2
death-associated protein kinase 2
chrX_-_73921828 0.653 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
Naa10



N(alpha)-acetyltransferase 10, NatA catalytic subunit



chr2_-_38644087 0.650 ENSMUST00000028083.5
Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr4_-_57143437 0.647 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr8_+_105170668 0.646 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr19_-_4615647 0.633 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr13_-_99900645 0.631 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr11_-_69579320 0.628 ENSMUST00000048139.5
Wrap53
WD repeat containing, antisense to Trp53
chr11_-_102407455 0.625 ENSMUST00000107098.1
ENSMUST00000018821.2
Slc25a39

solute carrier family 25, member 39

chr1_+_172499948 0.624 ENSMUST00000111230.1
Tagln2
transgelin 2
chr15_+_89355730 0.622 ENSMUST00000074552.5
ENSMUST00000088717.6
Ncaph2

non-SMC condensin II complex, subunit H2

chrX_-_73921930 0.618 ENSMUST00000033763.8
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr15_+_89355716 0.615 ENSMUST00000036987.5
Ncaph2
non-SMC condensin II complex, subunit H2
chr11_+_70657196 0.611 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr5_+_64160207 0.609 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr7_-_139582790 0.605 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr10_+_96616998 0.597 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chrX_-_7967817 0.585 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr4_+_116877376 0.565 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr17_+_46646225 0.565 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr1_-_75505641 0.563 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chr2_+_30416031 0.562 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr6_+_43265582 0.556 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_-_13193096 0.547 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr17_-_24696147 0.544 ENSMUST00000046839.8
Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr11_-_5261558 0.540 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr2_-_156839790 0.538 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr15_+_99702278 0.534 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr16_+_20673517 0.531 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chrX_+_96096034 0.511 ENSMUST00000117399.1
Msn
moesin
chr2_+_30416096 0.497 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr10_-_7663245 0.493 ENSMUST00000163085.1
ENSMUST00000159917.1
Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr7_-_127930066 0.489 ENSMUST00000032988.8
Prss8
protease, serine, 8 (prostasin)
chr17_-_57247632 0.481 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr7_+_16842896 0.478 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr4_+_97777780 0.471 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr19_+_46305682 0.468 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr4_-_135873801 0.466 ENSMUST00000030436.5
Pnrc2
proline-rich nuclear receptor coactivator 2
chr1_+_191098414 0.463 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr7_+_144838590 0.463 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr1_-_106714217 0.458 ENSMUST00000112751.1
Bcl2
B cell leukemia/lymphoma 2
chr15_-_89355655 0.437 ENSMUST00000023283.5
Lmf2
lipase maturation factor 2
chr7_+_126695355 0.433 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr16_-_94370994 0.431 ENSMUST00000113914.1
ENSMUST00000113905.1
Pigp

phosphatidylinositol glycan anchor biosynthesis, class P

chr2_+_174327747 0.431 ENSMUST00000087871.4
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr1_-_182282738 0.429 ENSMUST00000035295.5
Degs1
degenerative spermatocyte homolog 1 (Drosophila)
chr1_-_180813534 0.427 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr11_-_70656467 0.424 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr7_+_112427706 0.419 ENSMUST00000033030.7
Parva
parvin, alpha
chr11_+_98795495 0.417 ENSMUST00000037915.2
Msl1
male-specific lethal 1 homolog (Drosophila)
chr17_+_86963077 0.417 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr11_-_102407315 0.414 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39

solute carrier family 25, member 39

chr1_+_192190771 0.410 ENSMUST00000078470.5
ENSMUST00000110844.1
Kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr17_-_25868727 0.409 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr5_-_52566264 0.402 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr1_-_82291370 0.399 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr15_-_97767644 0.396 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr7_+_30565410 0.396 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chrX_+_161717055 0.395 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr18_+_60925644 0.394 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr6_+_124931378 0.392 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr9_-_110742577 0.384 ENSMUST00000006005.7
Pth1r
parathyroid hormone 1 receptor
chr7_+_16843049 0.383 ENSMUST00000086104.4
Prkd2
protein kinase D2
chr11_-_82871133 0.378 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr8_-_70659645 0.376 ENSMUST00000070173.7
Pgpep1
pyroglutamyl-peptidase I
chr3_+_51693771 0.375 ENSMUST00000099104.2
Gm10729
predicted gene 10729
chr10_-_80798476 0.359 ENSMUST00000036805.5
Plekhj1
pleckstrin homology domain containing, family J member 1
chr14_+_28511344 0.351 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr7_+_24884611 0.350 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr7_+_82337218 0.345 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr2_+_28205648 0.345 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr9_+_64960892 0.343 ENSMUST00000037504.5
Vwa9
von Willebrand factor A domain containing 9
chr5_-_3473178 0.337 ENSMUST00000168422.1
Gm17590
predicted gene, 17590
chr18_+_60925612 0.332 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr8_+_22192800 0.330 ENSMUST00000033866.8
Vps36
vacuolar protein sorting 36 (yeast)
chr4_-_150914401 0.330 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr13_-_55488038 0.329 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
Dbn1


drebrin 1


chr7_+_126847908 0.327 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr2_+_32535315 0.324 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr10_+_36974536 0.323 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr1_+_135818593 0.312 ENSMUST00000038760.8
Lad1
ladinin
chr7_-_132852606 0.309 ENSMUST00000120425.1
Mettl10
methyltransferase like 10
chrX_+_56963325 0.305 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr11_+_3202612 0.305 ENSMUST00000110049.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr7_+_24884651 0.299 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chr12_+_53248677 0.297 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr1_+_87183310 0.297 ENSMUST00000044533.8
Prss56
protease, serine 56
chr7_-_27355944 0.296 ENSMUST00000003857.6
Shkbp1
Sh3kbp1 binding protein 1
chr7_-_133015248 0.296 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr2_-_3419066 0.292 ENSMUST00000115082.3
Meig1
meiosis expressed gene 1
chr9_+_64960814 0.292 ENSMUST00000170517.1
Vwa9
von Willebrand factor A domain containing 9
chr14_+_122534305 0.289 ENSMUST00000154206.1
ENSMUST00000038374.6
ENSMUST00000135578.1
Pcca


propionyl-Coenzyme A carboxylase, alpha polypeptide


chr11_+_101325063 0.287 ENSMUST00000041095.7
ENSMUST00000107264.1
Aoc2

amine oxidase, copper containing 2 (retina-specific)

chr11_-_62539257 0.284 ENSMUST00000018653.1
Cenpv
centromere protein V
chr6_-_85933379 0.283 ENSMUST00000162660.1
Nat8b
N-acetyltransferase 8B
chr17_-_27820445 0.282 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chr7_-_127615208 0.279 ENSMUST00000122066.1
Zfp629
zinc finger protein 629
chr12_-_103242143 0.277 ENSMUST00000074416.3
Prima1
proline rich membrane anchor 1
chr15_-_36608959 0.276 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr16_-_94370647 0.268 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr17_-_46705002 0.268 ENSMUST00000002839.8
Ppp2r5d
protein phosphatase 2, regulatory subunit B (B56), delta isoform
chr7_+_45705518 0.264 ENSMUST00000107740.1
ENSMUST00000107741.1
Dbp

D site albumin promoter binding protein

chr11_+_60537978 0.264 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chrX_-_7947848 0.259 ENSMUST00000115642.1
ENSMUST00000033501.8
ENSMUST00000145675.1
Hdac6


histone deacetylase 6


chr7_-_31042078 0.258 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
Fxyd5






FXYD domain-containing ion transport regulator 5






chr7_+_97480928 0.254 ENSMUST00000026126.8
Ints4
integrator complex subunit 4
chr5_+_143403819 0.253 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr13_+_49187485 0.247 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr9_+_119937606 0.246 ENSMUST00000035100.5
Ttc21a
tetratricopeptide repeat domain 21A
chr9_+_58134535 0.245 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr18_+_61953048 0.244 ENSMUST00000051720.5
Sh3tc2
SH3 domain and tetratricopeptide repeats 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.7 2.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.7 2.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.7 4.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 2.0 GO:0036166 phenotypic switching(GO:0036166)
0.6 1.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.6 3.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 1.0 GO:0016115 terpenoid catabolic process(GO:0016115)
0.5 3.9 GO:0072615 interleukin-17 secretion(GO:0072615)
0.5 1.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.4 7.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.4 2.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4 0.4 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.4 2.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.4 1.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 1.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.4 3.9 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.3 3.8 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.3 2.0 GO:0060242 contact inhibition(GO:0060242)
0.3 1.0 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.3 2.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 0.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 0.8 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 1.2 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.2 1.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 0.7 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 1.5 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.2 0.6 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 0.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 0.7 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 1.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.2 1.0 GO:0032439 endosome localization(GO:0032439)
0.2 0.6 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.5 GO:0046671 regulation of cellular pH reduction(GO:0032847) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 1.5 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 1.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) protein kinase D signaling(GO:0089700)
0.1 1.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.4 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 2.2 GO:0043486 histone exchange(GO:0043486)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0031508 chromatin remodeling at centromere(GO:0031055) pericentric heterochromatin assembly(GO:0031508)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.8 GO:0001842 neural fold formation(GO:0001842)
0.1 0.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.1 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.1 0.2 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 2.7 GO:0009299 mRNA transcription(GO:0009299)
0.1 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 3.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.1 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.5 GO:0097421 liver regeneration(GO:0097421)
0.1 1.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.2 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.7 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.9 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.2 GO:2000054 regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.7 GO:0046697 decidualization(GO:0046697)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 1.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.5 GO:0070633 transepithelial transport(GO:0070633)
0.0 1.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.5 GO:0002467 germinal center formation(GO:0002467)
0.0 0.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.5 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762) response to mercury ion(GO:0046689)
0.0 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.0 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.5 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 0.2 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.3 GO:0050953 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.4 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.5 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.0 3.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7 2.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 2.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.9 GO:0061689 tricellular tight junction(GO:0061689)
0.3 2.1 GO:0031415 NatA complex(GO:0031415)
0.3 0.8 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 0.7 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.2 1.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 0.8 GO:0090537 CERF complex(GO:0090537)
0.2 0.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.2 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.5 GO:0034448 EGO complex(GO:0034448)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:1902737 dendritic filopodium(GO:1902737)
0.1 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.2 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 2.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 6.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.0 6.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0008142 oxysterol binding(GO:0008142)
0.8 3.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 3.3 GO:0019841 retinol binding(GO:0019841)
0.5 1.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 2.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.4 1.2 GO:0070052 collagen V binding(GO:0070052)
0.3 7.1 GO:0070410 co-SMAD binding(GO:0070410)
0.3 2.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.8 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.4 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 2.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.3 GO:0005118 sevenless binding(GO:0005118)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 7.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.0 GO:0051861 glycolipid binding(GO:0051861)
0.1 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 3.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 2.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.0 GO:0042393 histone binding(GO:0042393)
0.0 0.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 9.4 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 10.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 0.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 2.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.8 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.2 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.4 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.6 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 4.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 2.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 3.2 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.4 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.9 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 3.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 2.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.0 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.2 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression