Motif ID: Nfix

Z-value: 1.224


Transcription factors associated with Nfix:

Gene SymbolEntrez IDGene Name
Nfix ENSMUSG00000001911.10 Nfix

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfixmm10_v2_chr8_-_84773381_847734270.902.8e-07Click!


Activity profile for motif Nfix.

activity profile for motif Nfix


Sorted Z-values histogram for motif Nfix

Sorted Z-values for motif Nfix



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfix

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_141524379 10.498 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr4_+_48045144 5.008 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr1_-_56969864 4.566 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969827 4.450 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr13_+_16014457 4.350 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr16_+_42907563 3.784 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr13_+_83504032 3.646 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr5_+_66745835 3.393 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr9_+_89909775 3.392 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr18_-_78123324 3.262 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr7_-_103827922 3.217 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr5_+_66968961 3.182 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr4_-_46991842 3.025 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr3_+_156562141 3.018 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr18_+_34247685 2.974 ENSMUST00000066133.6
Apc
adenomatosis polyposis coli
chr13_+_42866247 2.902 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr7_-_97417730 2.851 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr4_+_102570065 2.631 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr18_-_23038656 2.584 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chrX_-_143933089 2.558 ENSMUST00000087313.3
Dcx
doublecortin
chr6_+_135362931 2.462 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr1_-_155417394 2.249 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr1_+_66321708 2.219 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr11_+_63128973 2.106 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr13_-_97747399 2.077 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr11_-_102897123 2.067 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr17_-_49564262 2.026 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr4_-_148287927 1.986 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr7_+_130936172 1.968 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr6_-_126166726 1.908 ENSMUST00000112244.2
ENSMUST00000050484.7
Ntf3

neurotrophin 3

chr12_-_83487708 1.853 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr8_-_83955205 1.802 ENSMUST00000098595.2
Gm10644
predicted gene 10644
chr11_-_116654245 1.800 ENSMUST00000021166.5
Cygb
cytoglobin
chr3_-_127409014 1.780 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr4_+_102430047 1.762 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_+_120842824 1.725 ENSMUST00000047875.8
Eef2k
eukaryotic elongation factor-2 kinase
chr2_-_45113255 1.702 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr7_-_134232005 1.697 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr5_-_18360384 1.658 ENSMUST00000074694.5
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr16_+_41532851 1.597 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr7_+_120843551 1.591 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr10_+_57784914 1.587 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr11_+_98836775 1.579 ENSMUST00000107479.2
Rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr11_+_97450136 1.575 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr10_-_109010955 1.562 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr10_+_57784859 1.560 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr4_-_42034726 1.548 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr6_+_92092369 1.543 ENSMUST00000113463.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr3_-_127408937 1.532 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr8_+_104170513 1.509 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr10_-_105574435 1.501 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr2_+_118663235 1.470 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_117133567 1.458 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr13_-_113663670 1.428 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr11_+_69095217 1.406 ENSMUST00000101004.2
Per1
period circadian clock 1
chr11_+_106084577 1.393 ENSMUST00000002044.9
Map3k3
mitogen-activated protein kinase kinase kinase 3
chr18_+_37955126 1.387 ENSMUST00000176902.1
ENSMUST00000176104.1
Rell2

RELT-like 2

chr4_+_102254739 1.365 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr14_+_64652524 1.364 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr10_-_125328957 1.259 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_+_42229726 1.219 ENSMUST00000066196.1
Gm9915
predicted gene 9915
chr5_+_64812336 1.197 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr12_-_27160311 1.151 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr2_-_45113216 1.143 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chr5_-_84417359 1.142 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr16_+_11405648 1.130 ENSMUST00000096273.2
Snx29
sorting nexin 29
chr4_-_14621805 1.129 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr10_-_89257578 1.098 ENSMUST00000182341.1
ENSMUST00000182613.1
Ano4

anoctamin 4

chr2_-_147186389 1.089 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr1_-_44218952 1.086 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr3_+_123267445 1.084 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr12_-_72408934 1.072 ENSMUST00000078505.7
Rtn1
reticulon 1
chr4_+_42035113 1.051 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr7_+_27195781 1.048 ENSMUST00000108379.1
ENSMUST00000179391.1
BC024978

cDNA sequence BC024978

chr3_-_127409044 1.039 ENSMUST00000182704.1
Ank2
ankyrin 2, brain
chr8_-_115706994 1.034 ENSMUST00000069009.6
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr7_+_28179469 1.022 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr16_+_43235856 1.018 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_+_20696175 1.010 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chrX_-_20950597 1.001 ENSMUST00000009550.7
Elk1
ELK1, member of ETS oncogene family
chr3_+_76593550 0.996 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chrX_-_57338598 0.995 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr12_-_84361802 0.982 ENSMUST00000021659.1
ENSMUST00000065536.2
Fam161b

family with sequence similarity 161, member B

chr9_-_44965519 0.966 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a


ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)


chr4_+_118961578 0.958 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr1_+_169929929 0.937 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr3_-_127408986 0.932 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
Ank2


ankyrin 2, brain


chr11_+_103133333 0.910 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr7_+_28180272 0.903 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr15_-_98871175 0.888 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr15_-_37458523 0.886 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr14_-_34503323 0.842 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr9_+_121366958 0.831 ENSMUST00000045903.6
Trak1
trafficking protein, kinesin binding 1
chr4_-_155992604 0.821 ENSMUST00000052185.3
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr1_+_23761749 0.813 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr11_-_102897146 0.810 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr18_-_6241470 0.810 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr9_-_42399709 0.806 ENSMUST00000160940.1
Tecta
tectorin alpha
chr5_-_123132651 0.798 ENSMUST00000031401.5
Rhof
ras homolog gene family, member f
chr11_+_54314960 0.787 ENSMUST00000064690.3
ENSMUST00000108899.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr6_-_115251839 0.786 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr3_-_58885212 0.781 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
Clrn1


clarin 1


chr17_-_24209377 0.759 ENSMUST00000024931.4
Ntn3
netrin 3
chr11_+_77216180 0.757 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr4_-_11981265 0.754 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr11_+_16257706 0.754 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr9_-_42399915 0.747 ENSMUST00000042190.7
Tecta
tectorin alpha
chr7_+_28180226 0.746 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr15_-_81697256 0.737 ENSMUST00000072910.5
Chadl
chondroadherin-like
chrX_+_163909132 0.728 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr1_-_64121389 0.718 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr16_+_27389911 0.691 ENSMUST00000143823.1
Ccdc50
coiled-coil domain containing 50
chr10_-_95415283 0.689 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr9_-_103222063 0.681 ENSMUST00000170904.1
Trf
transferrin
chr10_-_57532416 0.680 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr3_-_121283096 0.672 ENSMUST00000135818.1
ENSMUST00000137234.1
Tmem56

transmembrane protein 56

chrX_+_10485121 0.671 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chrX_+_166344692 0.655 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr5_+_137518880 0.655 ENSMUST00000031727.7
Gigyf1
GRB10 interacting GYF protein 1
chr10_-_95415484 0.632 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2

suppressor of cytokine signaling 2

chr10_-_89257790 0.628 ENSMUST00000045601.7
Ano4
anoctamin 4
chr9_-_123717576 0.619 ENSMUST00000026274.7
Lztfl1
leucine zipper transcription factor-like 1
chr11_-_75451083 0.615 ENSMUST00000132442.1
Wdr81
WD repeat domain 81
chr19_-_40588374 0.599 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr6_-_41636389 0.595 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr5_-_137741601 0.584 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr2_+_165992625 0.578 ENSMUST00000109252.1
ENSMUST00000088095.5
Ncoa3

nuclear receptor coactivator 3

chr1_+_23761926 0.569 ENSMUST00000063663.5
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chrX_+_104482774 0.565 ENSMUST00000087867.5
Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chrX_-_59568068 0.560 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr4_+_42714926 0.556 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr17_+_35135463 0.548 ENSMUST00000173535.1
ENSMUST00000173952.1
Bag6

BCL2-associated athanogene 6

chr7_-_105399991 0.548 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr1_-_162859919 0.537 ENSMUST00000134098.1
ENSMUST00000111518.1
Fmo1

flavin containing monooxygenase 1

chr15_-_75982442 0.527 ENSMUST00000183130.1
ENSMUST00000182172.1
Ccdc166

coiled-coil domain containing 166

chr1_-_132367879 0.527 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr15_-_88978958 0.521 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr6_+_128399766 0.519 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr2_-_116065798 0.511 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr16_-_55895279 0.510 ENSMUST00000099705.3
Nxpe3
neurexophilin and PC-esterase domain family, member 3
chr12_+_84362029 0.501 ENSMUST00000110278.1
ENSMUST00000145522.1
Coq6

coenzyme Q6 homolog (yeast)

chr19_-_40612160 0.496 ENSMUST00000132452.1
ENSMUST00000135795.1
ENSMUST00000025981.8
Tctn3


tectonic family member 3


chr4_+_148000722 0.492 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr2_+_163995503 0.486 ENSMUST00000131288.1
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr12_-_75735729 0.478 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr13_-_97747373 0.468 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr11_+_54314896 0.462 ENSMUST00000072178.4
ENSMUST00000101211.2
ENSMUST00000101213.2
Acsl6


acyl-CoA synthetase long-chain family member 6


chr4_+_82065855 0.451 ENSMUST00000151038.1
Gm5860
predicted gene 5860
chr16_+_65520503 0.449 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr2_-_37443096 0.444 ENSMUST00000102789.2
ENSMUST00000067043.4
ENSMUST00000112932.1
Zbtb26

Zbtb6
zinc finger and BTB domain containing 26

zinc finger and BTB domain containing 6
chrX_-_111697069 0.441 ENSMUST00000113422.2
ENSMUST00000038472.5
Hdx

highly divergent homeobox

chr12_-_40445754 0.436 ENSMUST00000069692.8
ENSMUST00000069637.7
Zfp277

zinc finger protein 277

chr11_+_49244191 0.424 ENSMUST00000167400.1
ENSMUST00000081794.6
Mgat1

mannoside acetylglucosaminyltransferase 1

chr1_-_64121456 0.413 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr11_-_94549165 0.413 ENSMUST00000040487.3
Rsad1
radical S-adenosyl methionine domain containing 1
chr8_+_120488416 0.408 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr3_-_57847478 0.408 ENSMUST00000120289.1
ENSMUST00000066882.8
Pfn2

profilin 2

chr2_-_4652086 0.405 ENSMUST00000035721.7
ENSMUST00000152362.1
Prpf18

PRP18 pre-mRNA processing factor 18 homolog (yeast)

chr13_-_41847626 0.383 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr7_-_102477902 0.382 ENSMUST00000061482.5
Olfr543
olfactory receptor 543
chr11_+_75348433 0.351 ENSMUST00000044530.2
Smyd4
SET and MYND domain containing 4
chr10_-_58675631 0.347 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr11_-_33276334 0.336 ENSMUST00000183831.1
Gm12117
predicted gene 12117
chr9_+_21184103 0.325 ENSMUST00000115458.2
Pde4a
phosphodiesterase 4A, cAMP specific
chr1_-_192855723 0.314 ENSMUST00000155579.1
Sertad4
SERTA domain containing 4
chr3_+_88616133 0.313 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr7_+_133637543 0.308 ENSMUST00000051169.6
2700050L05Rik
RIKEN cDNA 2700050L05 gene
chr13_-_28953690 0.306 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr10_-_81364846 0.301 ENSMUST00000131736.1
4930404N11Rik
RIKEN cDNA 4930404N11 gene
chr18_+_55057557 0.297 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr6_-_102464667 0.295 ENSMUST00000032159.6
Cntn3
contactin 3
chr6_+_128399881 0.295 ENSMUST00000120405.1
Nrip2
nuclear receptor interacting protein 2
chr2_+_72297895 0.292 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr7_+_27653906 0.288 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr12_+_84361968 0.282 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr7_+_130577334 0.280 ENSMUST00000059145.7
ENSMUST00000084513.4
Tacc2

transforming, acidic coiled-coil containing protein 2

chr1_+_87404916 0.272 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr1_-_172219715 0.262 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr7_+_133637686 0.254 ENSMUST00000128901.2
2700050L05Rik
RIKEN cDNA 2700050L05 gene
chr7_-_113347273 0.248 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr10_+_116177351 0.233 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr6_-_34910869 0.225 ENSMUST00000081214.5
Wdr91
WD repeat domain 91
chr15_-_81045467 0.222 ENSMUST00000135047.1
Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr2_+_153161303 0.219 ENSMUST00000089027.2
Tm9sf4
transmembrane 9 superfamily protein member 4
chr4_+_84884366 0.208 ENSMUST00000102819.3
Cntln
centlein, centrosomal protein
chr7_+_25659153 0.206 ENSMUST00000079634.6
Exosc5
exosome component 5
chr6_+_38551786 0.205 ENSMUST00000161227.1
Luc7l2
LUC7-like 2 (S. cerevisiae)
chr1_+_74544345 0.203 ENSMUST00000027362.7
Plcd4
phospholipase C, delta 4
chr5_-_123749393 0.200 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr2_+_35622160 0.200 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr9_-_44134481 0.197 ENSMUST00000180670.1
Gm10687
predicted gene 10687
chr5_+_104775911 0.195 ENSMUST00000055593.7
Gm8258
predicted gene 8258
chr2_-_165884636 0.176 ENSMUST00000177633.1
ENSMUST00000018050.7
ENSMUST00000088113.4
Zmynd8


zinc finger, MYND-type containing 8


chr18_-_56925509 0.173 ENSMUST00000102912.1
March3
membrane-associated ring finger (C3HC4) 3
chr12_-_55492587 0.172 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr5_-_103977360 0.169 ENSMUST00000048118.8
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr4_-_119415494 0.151 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chr1_-_52499980 0.145 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr9_+_59539643 0.136 ENSMUST00000026262.6
Hexa
hexosaminidase A
chr7_-_15879844 0.112 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx

cone-rod homeobox containing gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.2 3.6 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
1.1 3.3 GO:0071918 urea transmembrane transport(GO:0071918)
1.0 10.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.9 4.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.7 3.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.6 5.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 1.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.6 9.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 1.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 2.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 2.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 5.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 1.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 2.9 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.4 1.9 GO:0007403 glial cell fate determination(GO:0007403)
0.4 1.8 GO:0015671 oxygen transport(GO:0015671)
0.3 2.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.3 1.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.3 1.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 0.8 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.3 0.8 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.2 4.6 GO:0032060 bleb assembly(GO:0032060)
0.2 1.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 1.6 GO:0005513 detection of calcium ion(GO:0005513)
0.2 3.1 GO:0060134 prepulse inhibition(GO:0060134)
0.2 3.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.1 GO:0019532 oxalate transport(GO:0019532)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 0.4 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 2.8 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 2.9 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 4.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 3.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.5 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.6 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.3 GO:0003289 atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357)
0.1 0.7 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 3.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.6 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.5 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 2.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.5 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.2 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 3.2 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.5 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 8.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.2 GO:0045006 DNA deamination(GO:0045006)
0.0 0.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.9 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:1903756 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.7 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.7 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.0 GO:1903546 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.4 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.1 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.8 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0043512 inhibin A complex(GO:0043512)
0.8 3.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 2.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.6 3.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 3.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 2.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 5.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 5.3 GO:0031430 M band(GO:0031430)
0.2 3.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.6 GO:0031045 dense core granule(GO:0031045)
0.1 2.1 GO:0043218 compact myelin(GO:0043218)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 1.9 GO:0071565 nBAF complex(GO:0071565)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 7.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 5.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.7 GO:0099738 cell cortex region(GO:0099738)
0.0 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.1 GO:0030017 sarcomere(GO:0030017)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 1.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 2.6 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.9 GO:0005901 caveola(GO:0005901)
0.0 4.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 13.2 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.1 3.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.8 3.2 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.7 2.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.7 4.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.7 3.3 GO:0015265 urea channel activity(GO:0015265)
0.6 1.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.5 3.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 1.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 1.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.3 1.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 2.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 3.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 6.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 3.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.5 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.2 1.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 5.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 2.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.7 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 2.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 5.3 GO:0030507 spectrin binding(GO:0030507)
0.1 2.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 2.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 4.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 6.8 GO:0003779 actin binding(GO:0003779)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 4.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 6.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.7 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 3.0 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 3.7 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.9 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 1.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 3.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.5 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 2.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.3 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.1 4.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 3.0 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 4.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 3.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 3.0 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 5.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 3.4 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.9 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.9 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.3 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.2 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 4.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.7 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 2.6 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis