Motif ID: Crem_Jdp2

Z-value: 0.696

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cremmm10_v2_chr18_-_3281712_3281747-0.653.5e-03Click!
Jdp2mm10_v2_chr12_+_85599388_85599416-0.107.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_43952999 2.539 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr6_-_23248264 2.500 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr17_+_43953191 2.259 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr1_+_74791516 2.226 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr1_-_71653162 2.139 ENSMUST00000055226.6
Fn1
fibronectin 1
chr15_+_34238026 2.112 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr11_-_84525514 2.053 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr9_-_52679429 1.561 ENSMUST00000098768.2
AI593442
expressed sequence AI593442
chr8_-_24438937 1.543 ENSMUST00000052622.4
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr16_-_23890805 1.532 ENSMUST00000004480.3
Sst
somatostatin
chr9_+_44134562 1.520 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr4_+_32238950 1.520 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr11_+_84525669 1.348 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr1_+_71652837 1.336 ENSMUST00000097699.2
Apol7d
apolipoprotein L 7d
chr7_+_79500018 1.239 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr2_+_105668935 1.236 ENSMUST00000142772.1
Pax6
paired box gene 6
chr4_+_32238713 1.196 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr14_+_47472628 1.185 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr1_-_134079114 1.173 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr14_+_47472547 1.160 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr13_+_15463202 1.128 ENSMUST00000130065.1
Gli3
GLI-Kruppel family member GLI3
chr12_+_4082596 1.119 ENSMUST00000049584.5
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr4_+_141301228 1.113 ENSMUST00000006614.2
Epha2
Eph receptor A2
chr7_-_142899985 1.105 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr17_+_23679363 1.087 ENSMUST00000024699.2
Cldn6
claudin 6
chr15_-_12321899 1.069 ENSMUST00000180521.1
1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr5_-_106458440 1.066 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr7_-_38271310 1.057 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr2_+_19909769 1.035 ENSMUST00000114610.1
Etl4
enhancer trap locus 4
chr3_+_125404292 1.030 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_125404072 1.030 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_-_20976762 0.989 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr13_+_19623163 0.973 ENSMUST00000002883.5
Sfrp4
secreted frizzled-related protein 4
chr16_+_38562821 0.959 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chrX_-_56598069 0.958 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr11_+_84525647 0.958 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr1_+_184034381 0.914 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr9_+_102718424 0.892 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr7_+_79500081 0.886 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr5_+_142960343 0.883 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr8_+_45885479 0.850 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr16_+_38562806 0.844 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr9_-_96478660 0.839 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr7_-_137314394 0.837 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr10_-_42583628 0.832 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr13_-_64274879 0.808 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr7_-_30664986 0.806 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr12_+_4082574 0.797 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr2_+_167777467 0.788 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr5_-_69341699 0.784 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr12_+_52097737 0.782 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr11_+_52396414 0.776 ENSMUST00000109057.1
ENSMUST00000036952.4
9530068E07Rik

RIKEN cDNA 9530068E07 gene

chr4_-_123750236 0.775 ENSMUST00000102636.3
Akirin1
akirin 1
chr6_+_112273758 0.764 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr7_-_144939823 0.758 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr7_+_139389072 0.749 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr2_+_105668888 0.745 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr10_+_44268328 0.738 ENSMUST00000039286.4
Atg5
autophagy related 5
chr11_+_64435315 0.713 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr9_+_106170918 0.704 ENSMUST00000020490.5
Wdr82
WD repeat domain containing 82
chr4_+_56802337 0.703 ENSMUST00000045368.5
BC026590
cDNA sequence BC026590
chr9_+_66713719 0.690 ENSMUST00000085420.5
Car12
carbonic anyhydrase 12
chr9_+_66713686 0.686 ENSMUST00000071889.6
Car12
carbonic anyhydrase 12
chr3_-_36571952 0.685 ENSMUST00000029270.3
Ccna2
cyclin A2
chr7_-_118584669 0.685 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr1_-_79440039 0.682 ENSMUST00000049972.4
Scg2
secretogranin II
chr11_-_76243687 0.671 ENSMUST00000017430.5
Glod4
glyoxalase domain containing 4
chr10_+_96616998 0.659 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr2_+_164746028 0.657 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr6_+_134035691 0.655 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr6_-_50566535 0.651 ENSMUST00000161401.1
Cycs
cytochrome c, somatic
chr12_-_69159109 0.649 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr4_-_131838231 0.644 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr7_-_102210120 0.637 ENSMUST00000070165.5
Nup98
nucleoporin 98
chr9_-_64172879 0.636 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr1_+_95313607 0.631 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr7_+_46845832 0.624 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr1_+_107511489 0.621 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr8_-_84840627 0.616 ENSMUST00000003911.6
ENSMUST00000109761.2
ENSMUST00000128035.1
Rad23a


RAD23a homolog (S. cerevisiae)


chr14_-_67072465 0.590 ENSMUST00000089230.5
Ppp2r2a
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr4_+_21931291 0.589 ENSMUST00000029908.7
Faxc
failed axon connections homolog (Drosophila)
chr6_-_134792596 0.581 ENSMUST00000100857.3
Dusp16
dual specificity phosphatase 16
chr11_-_59163696 0.572 ENSMUST00000137433.1
ENSMUST00000054523.5
Iba57

IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

chr1_+_107511416 0.572 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr18_+_36348653 0.566 ENSMUST00000050584.3
Cystm1
cysteine-rich transmembrane module containing 1
chr11_+_101468164 0.560 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr2_+_122738495 0.546 ENSMUST00000005954.8
Bloc1s6
biogenesis of organelles complex-1, subunit 6, pallidin
chr12_+_79130777 0.543 ENSMUST00000021550.6
Arg2
arginase type II
chr8_+_72135247 0.542 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr11_+_52232183 0.534 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr6_+_113531675 0.529 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr5_+_24164963 0.521 ENSMUST00000049887.6
Nupl2
nucleoporin like 2
chr6_-_30304513 0.513 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr11_+_69324069 0.510 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr5_-_114443993 0.507 ENSMUST00000112245.1
Mmab
methylmalonic aciduria (cobalamin deficiency) type B homolog (human)
chr6_+_29694204 0.499 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr8_-_110997764 0.498 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chr5_-_25223153 0.496 ENSMUST00000066954.1
E130116L18Rik
RIKEN cDNA E130116L18 gene
chr16_-_4790220 0.494 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr2_-_3474954 0.488 ENSMUST00000060618.6
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr6_-_83033422 0.487 ENSMUST00000089651.5
Dok1
docking protein 1
chr5_-_137530990 0.485 ENSMUST00000132525.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr17_+_84511832 0.485 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr2_-_3475027 0.470 ENSMUST00000027956.2
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr1_-_92473801 0.467 ENSMUST00000027478.6
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
chr3_+_67374091 0.466 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr17_-_27907706 0.464 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_-_76243610 0.454 ENSMUST00000164022.1
ENSMUST00000168055.1
ENSMUST00000169701.1
Glod4


glyoxalase domain containing 4


chr8_-_4325096 0.452 ENSMUST00000098950.4
Elavl1
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr19_+_59260878 0.452 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr2_+_120609383 0.451 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr9_-_96478596 0.451 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr13_-_54688264 0.450 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr10_-_128176568 0.449 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr8_+_79711792 0.449 ENSMUST00000048147.7
Anapc10
anaphase promoting complex subunit 10
chr11_+_69324055 0.443 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr3_-_88762244 0.441 ENSMUST00000183267.1
Syt11
synaptotagmin XI
chr11_-_100939457 0.439 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr3_+_67374116 0.436 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr19_-_42129043 0.425 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr1_+_75236439 0.423 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr15_-_50889691 0.421 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr11_-_113751813 0.419 ENSMUST00000053536.4
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr1_-_165236892 0.412 ENSMUST00000043235.5
Tiprl
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
chr15_+_12321472 0.405 ENSMUST00000059680.5
Golph3
golgi phosphoprotein 3
chr1_-_184033998 0.404 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr5_-_121191365 0.402 ENSMUST00000100770.2
ENSMUST00000054547.7
Ptpn11

protein tyrosine phosphatase, non-receptor type 11

chr3_+_90248172 0.398 ENSMUST00000015467.8
Slc39a1
solute carrier family 39 (zinc transporter), member 1
chr8_-_92355764 0.397 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr11_-_59163281 0.395 ENSMUST00000069631.2
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr10_-_92722356 0.394 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr17_+_34982154 0.388 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_80629646 0.386 ENSMUST00000085435.5
Csnk1g2
casein kinase 1, gamma 2
chr17_+_34981847 0.384 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_132075250 0.381 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr17_+_34982099 0.381 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_-_4789887 0.380 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chr8_-_60954726 0.379 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr4_+_115737738 0.378 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr16_-_4789984 0.374 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr3_-_150073620 0.374 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr10_+_42583787 0.371 ENSMUST00000105497.1
ENSMUST00000144806.1
Ostm1

osteopetrosis associated transmembrane protein 1

chr10_+_128337761 0.369 ENSMUST00000005826.7
Cs
citrate synthase
chr11_+_52098681 0.369 ENSMUST00000020608.2
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr14_-_54870913 0.367 ENSMUST00000146642.1
Homez
homeodomain leucine zipper-encoding gene
chr2_-_156839790 0.365 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chrX_-_7188713 0.363 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr13_+_113035111 0.362 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr11_-_100939357 0.358 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr5_-_93206428 0.354 ENSMUST00000144514.1
Ccni
cyclin I
chr13_-_19395728 0.350 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr16_-_16829276 0.350 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr17_-_31855782 0.349 ENSMUST00000024839.4
Sik1
salt inducible kinase 1
chr11_-_100939540 0.349 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr18_+_36348739 0.343 ENSMUST00000152804.2
Cystm1
cysteine-rich transmembrane module containing 1
chr12_+_40222758 0.341 ENSMUST00000038121.4
Gm7008
predicted gene 7008
chr11_-_102185239 0.338 ENSMUST00000021297.5
Lsm12
LSM12 homolog (S. cerevisiae)
chr17_+_75005523 0.338 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr12_-_21417356 0.336 ENSMUST00000103002.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr9_+_77917364 0.334 ENSMUST00000034904.7
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr17_+_70929006 0.334 ENSMUST00000092011.6
Gm16519
predicted gene, 16519
chr18_-_56562187 0.333 ENSMUST00000171844.2
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr4_-_56802265 0.333 ENSMUST00000030140.2
Ikbkap
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr7_+_139248477 0.331 ENSMUST00000093993.3
ENSMUST00000172136.1
Pwwp2b

PWWP domain containing 2B

chr13_+_113342548 0.329 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr2_+_164745979 0.328 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr2_+_164456936 0.328 ENSMUST00000109352.1
Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr17_-_45573253 0.325 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr15_+_99393610 0.323 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr3_-_138143352 0.315 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr16_-_4077778 0.314 ENSMUST00000006137.8
Trap1
TNF receptor-associated protein 1
chr12_-_21417591 0.313 ENSMUST00000135088.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr19_-_24961545 0.311 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr17_-_84466186 0.310 ENSMUST00000047524.8
Thada
thyroid adenoma associated
chr8_-_106011422 0.310 ENSMUST00000058579.5
Ddx28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr13_-_53473074 0.305 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr8_+_92674289 0.304 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr3_-_146108047 0.303 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr12_-_21417526 0.302 ENSMUST00000049531.9
ENSMUST00000155480.1
Ywhaq

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

chr7_+_138846335 0.302 ENSMUST00000041097.6
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr7_-_44748306 0.301 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
Zfp473


zinc finger protein 473


chr11_+_108682602 0.300 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr11_-_88718223 0.298 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr6_-_131293187 0.298 ENSMUST00000032307.5
Magohb
mago-nashi homolog B (Drosophila)
chr15_-_12592556 0.295 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr3_+_90072641 0.295 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr2_-_36136602 0.294 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr11_-_102185202 0.294 ENSMUST00000107156.2
Lsm12
LSM12 homolog (S. cerevisiae)
chr19_-_42128982 0.293 ENSMUST00000161873.1
Avpi1
arginine vasopressin-induced 1
chr15_+_59648644 0.292 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr2_+_156840077 0.292 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr3_+_129199919 0.290 ENSMUST00000029657.9
ENSMUST00000106382.4
Pitx2

paired-like homeodomain transcription factor 2

chr10_-_117845935 0.289 ENSMUST00000064667.7
Rap1b
RAS related protein 1b
chr8_+_92674826 0.286 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chr18_-_80151467 0.286 ENSMUST00000066743.9
Adnp2
ADNP homeobox 2
chrX_-_167209149 0.279 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr4_+_8690399 0.278 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr12_-_40223149 0.277 ENSMUST00000171553.1
ENSMUST00000001672.5
Ifrd1

interferon-related developmental regulator 1

chr11_+_69323963 0.274 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr5_-_22550279 0.272 ENSMUST00000030872.5
Orc5
origin recognition complex, subunit 5

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.7 2.1 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.6 1.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.5 1.4 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.4 2.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 2.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.4 1.5 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.4 1.1 GO:0014028 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319)
0.3 1.0 GO:0035973 aggrephagy(GO:0035973)
0.3 1.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.3 1.1 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3 1.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.3 4.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 2.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 0.9 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 0.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 1.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 0.5 GO:0010958 regulation of amino acid import(GO:0010958)
0.2 1.4 GO:0055064 carbon dioxide transport(GO:0015670) chloride ion homeostasis(GO:0055064)
0.2 1.0 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.2 0.5 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.4 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.4 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 0.3 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 1.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 0.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 1.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.3 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 1.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.5 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.3 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 1.0 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.7 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 1.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.2 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 0.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.2 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.3 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 0.3 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0061084 negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.6 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 1.1 GO:0001709 cell fate determination(GO:0001709)
0.0 0.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0010886 regulation of cholesterol storage(GO:0010885) positive regulation of cholesterol storage(GO:0010886) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.5 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0030432 peristalsis(GO:0030432)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0006706 steroid catabolic process(GO:0006706) negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0003016 respiratory system process(GO:0003016)
0.0 0.9 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.0 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 1.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.4 1.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 0.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 0.6 GO:1990423 RZZ complex(GO:1990423)
0.2 0.8 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0071437 invadopodium(GO:0071437)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.0 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 2.1 GO:0045340 mercury ion binding(GO:0045340)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 2.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 0.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 2.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 1.1 GO:0035240 dopamine binding(GO:0035240)
0.2 1.0 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 0.7 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 1.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 1.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 1.0 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 1.1 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.7 GO:0032564 dATP binding(GO:0032564)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0035473 lipase binding(GO:0035473)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 1.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.0 GO:0048156 tau protein binding(GO:0048156)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.4 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.6 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.8 ST_STAT3_PATHWAY STAT3 Pathway
0.1 0.4 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 2.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 4.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway
0.0 0.0 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.5 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 2.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.7 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells