Motif ID: Alx4

Z-value: 0.530


Transcription factors associated with Alx4:

Gene SymbolEntrez IDGene Name
Alx4 ENSMUSG00000040310.6 Alx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx4mm10_v2_chr2_+_93642307_93642388-0.465.8e-02Click!


Activity profile for motif Alx4.

activity profile for motif Alx4


Sorted Z-values histogram for motif Alx4

Sorted Z-values for motif Alx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Alx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_26989974 1.715 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr10_+_97479470 1.569 ENSMUST00000105287.3
Dcn
decorin
chr9_+_123366921 1.423 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr9_+_119063429 1.307 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr11_+_58171648 1.295 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr10_-_77166545 1.224 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr3_+_146121655 1.189 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chrM_+_9452 1.173 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr10_-_37138863 1.163 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr8_-_4779513 0.997 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr2_+_20737306 0.988 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr15_+_9436028 0.932 ENSMUST00000042360.3
Capsl
calcyphosine-like
chrM_+_8600 0.921 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrM_+_2743 0.905 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr6_-_136875794 0.898 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr13_-_100786402 0.892 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chrX_-_134111852 0.865 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr3_+_94372794 0.863 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr13_+_104229366 0.846 ENSMUST00000022227.6
Cenpk
centromere protein K
chr4_+_105789869 0.840 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr5_-_149053038 0.809 ENSMUST00000085546.6
Hmgb1
high mobility group box 1
chr1_-_89933290 0.805 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr11_+_59306920 0.801 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr19_-_29334646 0.798 ENSMUST00000044143.5
Rln1
relaxin 1
chr19_+_55895508 0.769 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr8_-_106573461 0.757 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr2_+_71389239 0.756 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr17_-_53867041 0.742 ENSMUST00000061311.7
Mrps36-ps1
mitichondrial ribosomal protein S36, pseudogene 1
chr10_-_81350389 0.716 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr10_-_81350191 0.707 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr8_+_23411490 0.694 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr13_-_81710937 0.690 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr9_+_108339048 0.679 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr2_-_144270852 0.673 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr2_+_126556128 0.673 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr9_+_109832998 0.655 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr10_-_81350305 0.643 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr3_+_55782500 0.637 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr3_+_89459118 0.633 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr1_-_152386675 0.617 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr17_-_48432723 0.615 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr17_-_26099257 0.607 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr10_-_128626464 0.586 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr7_+_28808795 0.584 ENSMUST00000172529.1
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr12_-_80643799 0.582 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr14_-_118237016 0.560 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chrM_+_7005 0.559 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr13_+_90923122 0.549 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr1_-_133610253 0.546 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr11_+_98026695 0.546 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr7_+_101896340 0.538 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr13_-_102905740 0.528 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr10_-_128804353 0.520 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr1_-_175979114 0.518 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr1_-_152386589 0.515 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr16_-_45844228 0.515 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr2_-_105017015 0.512 ENSMUST00000111110.2
ENSMUST00000028592.5
Eif3m

eukaryotic translation initiation factor 3, subunit M

chr11_-_115419917 0.507 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr17_-_15527281 0.495 ENSMUST00000154293.1
ENSMUST00000054450.6
Pdcd2

programmed cell death 2

chrX_+_56787701 0.489 ENSMUST00000151033.1
Fhl1
four and a half LIM domains 1
chr8_-_84662841 0.488 ENSMUST00000060427.4
Ier2
immediate early response 2
chr4_+_132274385 0.488 ENSMUST00000105963.1
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_+_24490678 0.484 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr9_-_22117123 0.483 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr2_+_91257323 0.480 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr15_-_79774383 0.467 ENSMUST00000069877.5
Dnal4
dynein, axonemal, light chain 4
chr10_+_37139558 0.463 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr17_-_55915870 0.458 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr1_-_72284248 0.457 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr17_+_31520115 0.456 ENSMUST00000046288.8
ENSMUST00000064798.8
Ndufv3

NADH dehydrogenase (ubiquinone) flavoprotein 3

chr2_+_174327747 0.449 ENSMUST00000087871.4
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr1_-_163725123 0.448 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr14_+_54686171 0.448 ENSMUST00000038539.6
1700123O20Rik
RIKEN cDNA 1700123O20 gene
chr7_+_127233227 0.447 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr15_-_64922290 0.441 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr5_-_3647806 0.440 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr15_-_79774408 0.429 ENSMUST00000023055.6
Dnal4
dynein, axonemal, light chain 4
chr5_-_138170992 0.427 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_-_9140374 0.426 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr5_-_151651216 0.426 ENSMUST00000038131.9
Rfc3
replication factor C (activator 1) 3
chr18_-_56975333 0.420 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr7_-_45103747 0.419 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr13_-_102906046 0.417 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr4_+_136172367 0.413 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr11_+_98026918 0.412 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr15_+_102326400 0.408 ENSMUST00000165717.1
Pfdn5
prefoldin 5
chr9_+_102834961 0.403 ENSMUST00000035142.6
Ryk
receptor-like tyrosine kinase
chr11_-_4095344 0.402 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr10_+_18845071 0.398 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr4_+_132274369 0.392 ENSMUST00000030731.4
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr1_+_161070767 0.391 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr18_-_36454487 0.380 ENSMUST00000025204.5
Pfdn1
prefoldin 1
chr1_+_93685574 0.379 ENSMUST00000027499.6
Bok
BCL2-related ovarian killer protein
chr8_-_70510322 0.376 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
Uba52


ubiquitin A-52 residue ribosomal protein fusion product 1


chr17_+_80290206 0.373 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr5_-_138171248 0.368 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr3_+_89459325 0.368 ENSMUST00000107410.1
Pmvk
phosphomevalonate kinase
chr9_-_71163224 0.357 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr9_-_78480736 0.355 ENSMUST00000156988.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr17_-_43543639 0.354 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr3_-_57294880 0.351 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr12_-_113361232 0.350 ENSMUST00000103423.1
Ighg3
Immunoglobulin heavy constant gamma 3
chr7_+_38183217 0.347 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chrX_-_23266751 0.345 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr10_-_8886033 0.344 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr3_+_32708546 0.340 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr12_+_111814170 0.337 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr7_+_3703979 0.336 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr3_-_100489324 0.334 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr1_+_24177610 0.324 ENSMUST00000054588.8
Col9a1
collagen, type IX, alpha 1
chr11_-_51606840 0.324 ENSMUST00000074669.3
ENSMUST00000101249.2
ENSMUST00000109103.3
Hnrnpab


heterogeneous nuclear ribonucleoprotein A/B


chr11_-_11970540 0.323 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr4_+_145510759 0.322 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr9_-_55512156 0.315 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr2_-_155357392 0.314 ENSMUST00000165234.1
ENSMUST00000077626.6
Pigu

phosphatidylinositol glycan anchor biosynthesis, class U

chr13_+_44121167 0.312 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr15_+_102326369 0.311 ENSMUST00000169637.1
ENSMUST00000165671.1
Pfdn5

prefoldin 5

chr5_-_87490869 0.311 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr5_+_114707760 0.304 ENSMUST00000094441.4
Tchp
trichoplein, keratin filament binding
chr2_-_73453918 0.303 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr2_+_144270900 0.303 ENSMUST00000028910.2
ENSMUST00000110027.1
Mgme1

mitochondrial genome maintainance exonuclease 1

chr4_-_129227883 0.300 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr12_-_87444017 0.299 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr1_-_172027269 0.299 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr8_-_21906412 0.297 ENSMUST00000051965.4
Defb11
defensin beta 11
chr19_+_5474681 0.296 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr19_-_11604828 0.294 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr11_+_109543694 0.289 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr13_-_58354862 0.288 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr7_-_30559828 0.282 ENSMUST00000108164.1
Lin37
lin-37 homolog (C. elegans)
chr16_-_16869255 0.277 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr2_+_32606946 0.277 ENSMUST00000113290.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr2_+_109917639 0.275 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr10_-_80798476 0.273 ENSMUST00000036805.5
Plekhj1
pleckstrin homology domain containing, family J member 1
chr8_+_84689308 0.273 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chr2_-_160619971 0.271 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr14_-_66124482 0.268 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr2_-_132247747 0.264 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chrM_+_10167 0.263 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr14_-_69707546 0.263 ENSMUST00000118374.1
R3hcc1
R3H domain and coiled-coil containing 1
chr5_+_135994796 0.262 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
Dtx2




deltex 2 homolog (Drosophila)




chr6_-_87335758 0.255 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr17_-_47834682 0.251 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr8_+_84689247 0.249 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
Trmt1




tRNA methyltransferase 1




chr7_-_30559600 0.249 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr4_-_150914401 0.239 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr2_-_33718789 0.239 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr8_+_94152607 0.231 ENSMUST00000034211.8
Mt3
metallothionein 3
chr1_-_155527083 0.231 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr5_-_114823460 0.228 ENSMUST00000140374.1
ENSMUST00000100850.4
Gm20499
2610524H06Rik
predicted gene 20499
RIKEN cDNA 2610524H06 gene
chr2_+_131491764 0.227 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr16_-_10543028 0.224 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr6_-_69243445 0.219 ENSMUST00000101325.3
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr7_+_101896817 0.219 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr16_-_35363842 0.217 ENSMUST00000043521.4
Sec22a
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr5_-_100373484 0.216 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr14_-_69707493 0.216 ENSMUST00000121142.1
R3hcc1
R3H domain and coiled-coil containing 1
chr7_+_29238434 0.215 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_116843278 0.211 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr2_+_151542483 0.210 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr5_+_3543812 0.208 ENSMUST00000115527.3
Fam133b
family with sequence similarity 133, member B
chr2_+_125068118 0.204 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr10_-_33951190 0.204 ENSMUST00000048222.4
Zufsp
zinc finger with UFM1-specific peptidase domain
chr7_-_142656018 0.203 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr11_-_115187321 0.196 ENSMUST00000103038.1
ENSMUST00000103039.1
ENSMUST00000103040.4
Nat9


N-acetyltransferase 9 (GCN5-related, putative)


chr4_+_43493345 0.195 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr16_+_18836573 0.192 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chr11_+_62551676 0.191 ENSMUST00000136938.1
Ubb
ubiquitin B
chr10_+_128337761 0.186 ENSMUST00000005826.7
Cs
citrate synthase
chr11_-_102946688 0.185 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr3_-_67515487 0.185 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr18_-_10706688 0.185 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr7_-_19562377 0.183 ENSMUST00000058444.8
Ppp1r37
protein phosphatase 1, regulatory subunit 37
chr12_+_10390756 0.178 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr1_-_78488846 0.176 ENSMUST00000068333.7
ENSMUST00000170217.1
Farsb

phenylalanyl-tRNA synthetase, beta subunit

chr1_-_65186456 0.176 ENSMUST00000169032.1
Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chr4_+_95557494 0.176 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr17_+_29274078 0.175 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr6_-_83506895 0.172 ENSMUST00000113888.1
ENSMUST00000014698.3
Dguok

deoxyguanosine kinase

chr9_-_123678873 0.170 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr19_+_8735808 0.164 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr8_-_83442648 0.163 ENSMUST00000167525.1
Scoc
short coiled-coil protein
chr9_-_123678782 0.162 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr14_+_73138755 0.161 ENSMUST00000171070.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr11_-_79962374 0.157 ENSMUST00000108241.1
ENSMUST00000043152.5
Utp6

UTP6, small subunit (SSU) processome component, homolog (yeast)

chr15_+_98571004 0.157 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr7_+_19361207 0.155 ENSMUST00000047621.7
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr1_+_86021935 0.154 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chrM_+_11734 0.153 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr9_+_99629823 0.153 ENSMUST00000112886.2
Dzip1l
DAZ interacting protein 1-like
chr19_+_5088534 0.151 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr12_-_55302974 0.151 ENSMUST00000021410.8
Ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
chr7_+_12927410 0.147 ENSMUST00000045870.4
2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr19_-_41933276 0.142 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr17_-_56036546 0.138 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chr17_-_59013264 0.136 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr14_-_59365410 0.135 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d

PHD finger protein 11D

chr6_+_134640940 0.131 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr10_-_33624587 0.126 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr1_-_161070613 0.123 ENSMUST00000035430.3
Dars2
aspartyl-tRNA synthetase 2 (mitochondrial)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.3 1.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 0.8 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.3 1.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.7 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 0.7 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 1.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.8 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.7 GO:0018158 protein oxidation(GO:0018158)
0.1 2.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.4 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.8 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.8 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.9 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.1 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.9 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 1.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.4 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.4 GO:0046689 response to mercury ion(GO:0046689)
0.1 1.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.9 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.3 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.3 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.0 0.1 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.5 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.7 GO:0006907 pinocytosis(GO:0006907)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 1.8 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0010424 DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.0 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.4 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 1.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.9 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0051900 regulation of mitochondrial depolarization(GO:0051900)
0.0 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 1.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 1.2 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.9 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.9 GO:0000125 PCAF complex(GO:0000125)
0.1 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.1 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.7 GO:0097422 tubular endosome(GO:0097422)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.7 GO:0097413 Lewy body(GO:0097413)
0.1 1.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.6 GO:0034709 methylosome(GO:0034709)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 2.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0044301 climbing fiber(GO:0044301)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0070469 respiratory chain(GO:0070469)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.1 GO:1990393 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 0.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 0.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 1.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 0.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 2.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 2.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.7 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.8 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.0 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.0 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.6 PID_MYC_PATHWAY C-MYC pathway
0.0 1.5 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID_P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.9 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.7 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.8 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.0 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.0 0.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 1.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)