Motif ID: Gsx1_Alx1_Mixl1_Lbx2

Z-value: 0.640


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gsx1mm10_v2_chr5_+_147188678_147188696-0.503.6e-02Click!
Alx1mm10_v2_chr10_-_103028771_1030287820.145.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx1_Alx1_Mixl1_Lbx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_62766153 3.462 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_103550368 3.404 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr5_+_139543889 3.251 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr13_+_44121167 1.899 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr1_+_137928100 1.799 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chrX_+_56454871 1.625 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chrM_+_7005 1.623 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr17_+_45734506 1.423 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr2_-_116067391 1.379 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr3_-_110143937 1.376 ENSMUST00000051253.3
Ntng1
netrin G1
chr2_+_116067213 1.326 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr5_-_62765618 1.313 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_152754156 1.224 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr8_-_84662841 1.117 ENSMUST00000060427.4
Ier2
immediate early response 2
chrX_-_157415286 1.115 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr7_+_29071597 0.995 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr16_-_26989974 0.884 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr1_-_163725123 0.862 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr11_+_29373618 0.857 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr5_-_84417359 0.785 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr3_-_66296807 0.771 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr14_+_124005355 0.734 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr7_+_64185459 0.706 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr5_+_15516489 0.675 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr6_+_134929118 0.639 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chrM_+_2743 0.634 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr11_+_23306884 0.612 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr4_-_24430838 0.609 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr4_-_14621805 0.608 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chrX_-_37110257 0.570 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr3_-_88410295 0.569 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr11_+_23306910 0.543 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr12_-_111813834 0.530 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr14_+_53324632 0.526 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr13_-_83729544 0.514 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr1_-_72284248 0.512 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr13_+_23575753 0.504 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chrX_-_9256899 0.482 ENSMUST00000115553.2
Gm14862
predicted gene 14862
chr6_-_147264124 0.480 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr8_-_105637403 0.468 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr13_+_23544052 0.438 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr2_-_84425258 0.433 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr7_-_19699008 0.414 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr9_-_112187766 0.413 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chrM_+_11734 0.406 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr1_+_110099295 0.403 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chrM_+_10167 0.394 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr3_+_125404072 0.390 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr2_+_25372315 0.370 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr13_-_53473074 0.366 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr2_-_72986716 0.351 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr9_+_113930934 0.345 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1

upstream binding protein 1

chr17_+_46161021 0.336 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr9_-_55919605 0.333 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr16_-_45724600 0.319 ENSMUST00000096057.4
Tagln3
transgelin 3
chr4_-_14621669 0.318 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr15_+_55307743 0.317 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr12_+_59066908 0.313 ENSMUST00000021381.4
Pnn
pinin
chr13_-_103764502 0.311 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr13_-_27582168 0.310 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr3_-_49757257 0.303 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr6_+_143285988 0.303 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr7_+_5015466 0.302 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chr13_+_8202885 0.297 ENSMUST00000139438.1
ENSMUST00000135574.1
Adarb2

adenosine deaminase, RNA-specific, B2

chr3_-_87930121 0.297 ENSMUST00000005016.9
Rrnad1
ribosomal RNA adenine dimethylase domain containing 1
chr5_+_135106881 0.295 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr6_-_124779686 0.292 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr13_-_78196373 0.291 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr3_+_125404292 0.290 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chrM_-_14060 0.290 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr17_+_34039437 0.283 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr12_+_49401277 0.282 ENSMUST00000056234.3
Gm9804
predicted gene 9804
chr17_-_57247632 0.282 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr12_+_74297474 0.281 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr4_-_42661893 0.281 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr15_+_36179299 0.280 ENSMUST00000047348.3
Spag1
sperm associated antigen 1
chr13_+_118714678 0.279 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr4_+_154964117 0.278 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr7_+_30565410 0.277 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr10_+_39612934 0.276 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr9_+_118478344 0.273 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_+_170308802 0.271 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr9_-_71163224 0.269 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr7_+_43690418 0.268 ENSMUST00000056329.6
Klk14
kallikrein related-peptidase 14
chr4_-_14621494 0.267 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chrX_+_103356464 0.265 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr13_-_41273977 0.261 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chrM_+_7759 0.259 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr3_+_94398517 0.259 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr9_+_72806874 0.255 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr10_-_53647080 0.254 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chrX_-_134111852 0.251 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr5_+_138187485 0.249 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr12_+_109545390 0.247 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr2_-_147186389 0.241 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr6_-_136875794 0.239 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr6_+_37870786 0.235 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr5_+_14025305 0.232 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_+_79818031 0.231 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr5_-_20882072 0.231 ENSMUST00000118174.1
Phtf2
putative homeodomain transcription factor 2
chr12_+_102128718 0.229 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_79515618 0.226 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr1_-_75046639 0.223 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr3_-_146495115 0.220 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr1_+_195017399 0.219 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chrX_-_133981765 0.219 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
Sytl4



synaptotagmin-like 4



chr7_+_6474088 0.216 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr7_+_49910112 0.212 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr16_+_14705832 0.212 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr7_+_123123870 0.211 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr7_-_19399859 0.209 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr8_-_120228221 0.207 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr3_-_54714353 0.207 ENSMUST00000178832.1
Gm21958
predicted gene, 21958
chr11_+_16752203 0.206 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr11_-_98053415 0.206 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr10_-_76110956 0.206 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr6_-_85765744 0.205 ENSMUST00000050780.7
Cml3
camello-like 3
chr13_+_67833235 0.205 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr4_+_136143497 0.205 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr1_+_186749368 0.204 ENSMUST00000180869.1
A430105J06Rik
RIKEN cDNA A430105J06 gene
chr1_+_63176818 0.203 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr6_-_57535422 0.200 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr3_+_96269695 0.200 ENSMUST00000051089.3
ENSMUST00000177113.1
Hist2h2bb

histone cluster 2, H2bb

chr3_+_32436151 0.197 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr17_-_47834682 0.193 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr5_+_8893677 0.192 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr17_+_36958623 0.191 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr10_-_95673451 0.185 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr2_-_27475622 0.185 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
Brd3


bromodomain containing 3


chr9_-_22208546 0.184 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr15_-_35938009 0.183 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr17_+_35424842 0.182 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr13_-_113663670 0.180 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr12_+_111814170 0.178 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr7_+_51879041 0.178 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr15_+_18818895 0.178 ENSMUST00000166873.2
Cdh10
cadherin 10
chr8_-_67818284 0.177 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr10_-_45470201 0.176 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr11_+_59306920 0.173 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr8_-_67818218 0.172 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr11_+_69838514 0.171 ENSMUST00000133967.1
ENSMUST00000094065.4
Tmem256

transmembrane protein 256

chr3_-_130730375 0.170 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr9_-_123678782 0.168 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr6_+_17749170 0.167 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr3_-_79841729 0.167 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr8_+_45658666 0.167 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr2_-_168767029 0.163 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chrX_-_139871637 0.161 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr13_-_97747373 0.161 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_79456750 0.161 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr6_+_3993776 0.160 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_85288419 0.156 ENSMUST00000121930.1
Acyp1
acylphosphatase 1, erythrocyte (common) type
chr1_+_10056922 0.154 ENSMUST00000149214.1
Cspp1
centrosome and spindle pole associated protein 1
chr2_+_9882622 0.153 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr4_+_3940747 0.152 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr7_-_87493371 0.151 ENSMUST00000004770.5
Tyr
tyrosinase
chr5_+_17574268 0.151 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_128549125 0.149 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
Rpl41


ribosomal protein L41


chr10_-_88683021 0.148 ENSMUST00000004473.8
Spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr13_-_32781716 0.148 ENSMUST00000134352.1
ENSMUST00000057428.4
Mylk4

myosin light chain kinase family, member 4

chr9_+_13827708 0.148 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr13_-_71963713 0.147 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr11_-_109298090 0.147 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr17_+_34592248 0.146 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr8_+_45658731 0.144 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr15_+_102326172 0.143 ENSMUST00000170627.1
Pfdn5
prefoldin 5
chr4_+_154960915 0.142 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr8_-_106573461 0.140 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr18_+_59062282 0.137 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr11_-_29247208 0.136 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr8_-_57653023 0.135 ENSMUST00000034021.5
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr5_+_136116631 0.134 ENSMUST00000111127.1
ENSMUST00000041366.7
ENSMUST00000111129.1
Polr2j


polymerase (RNA) II (DNA directed) polypeptide J


chr16_-_74411292 0.134 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr12_+_38783503 0.134 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr15_+_102326116 0.134 ENSMUST00000166658.1
ENSMUST00000062492.4
Pfdn5

prefoldin 5

chr11_-_31671863 0.133 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr3_-_46447939 0.132 ENSMUST00000166505.1
Pabpc4l
poly(A) binding protein, cytoplasmic 4-like
chr12_+_52516077 0.131 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr5_+_123907175 0.131 ENSMUST00000023869.8
Denr
density-regulated protein
chr2_+_18064564 0.131 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr7_-_100656953 0.130 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr15_+_9436028 0.130 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr9_-_13827029 0.128 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr15_+_102326400 0.126 ENSMUST00000165717.1
Pfdn5
prefoldin 5
chr10_-_128744014 0.126 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chrX_+_9885622 0.125 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr7_+_114745685 0.124 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr1_+_164503306 0.124 ENSMUST00000181831.1
Gm26685
predicted gene, 26685
chr19_-_42129043 0.124 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr1_+_104768510 0.124 ENSMUST00000062528.8
Cdh20
cadherin 20
chr6_-_83121385 0.122 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr10_+_128747850 0.122 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr13_+_22043189 0.121 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr3_+_122044428 0.121 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr15_-_35938186 0.118 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr5_-_107875035 0.118 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr1_+_128103297 0.117 ENSMUST00000036288.4
R3hdm1
R3H domain containing 1
chr2_-_119271202 0.117 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr5_-_137836210 0.116 ENSMUST00000110980.1
ENSMUST00000058897.4
Pilra

paired immunoglobin-like type 2 receptor alpha

chr2_+_91257323 0.115 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.2 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.1 0.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.8 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 0.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.3 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 2.7 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.0 2.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 1.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.5 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.9 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.6 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.2 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 0.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.4 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 3.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 4.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0000150 recombinase activity(GO:0000150)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0003681 bent DNA binding(GO:0003681)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 0.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 4.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants