Motif ID: Relb
Z-value: 0.641

Transcription factors associated with Relb:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Relb | ENSMUSG00000002983.10 | Relb |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Relb | mm10_v2_chr7_-_19629355_19629451 | 0.64 | 3.9e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.4 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.5 | 3.3 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.5 | 2.8 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.4 | 2.1 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
0.4 | 1.1 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.3 | 0.8 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
0.2 | 0.5 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
0.1 | 0.7 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.1 | 0.6 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
0.1 | 1.0 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.1 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.1 | 0.4 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
0.1 | 0.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.1 | 0.7 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.1 | 2.2 | GO:0010842 | retina layer formation(GO:0010842) |
0.1 | 0.4 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.1 | 2.6 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.1 | 0.3 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.0 | 0.1 | GO:0061744 | motor behavior(GO:0061744) |
0.0 | 0.6 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 0.4 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.0 | 0.4 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
0.0 | 0.4 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.0 | 0.6 | GO:0016322 | neuron remodeling(GO:0016322) |
0.0 | 1.7 | GO:0060612 | adipose tissue development(GO:0060612) |
0.0 | 0.3 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.1 | GO:0009597 | detection of virus(GO:0009597) |
0.0 | 0.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.1 | GO:0071499 | response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499) |
0.0 | 0.1 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.3 | 2.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.2 | 2.6 | GO:0042581 | specific granule(GO:0042581) |
0.2 | 2.8 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 0.5 | GO:0033010 | paranodal junction(GO:0033010) |
0.0 | 0.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.0 | 0.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 1.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.3 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.8 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.3 | 2.4 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.2 | 0.6 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.5 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903) |
0.1 | 0.4 | GO:0004103 | choline kinase activity(GO:0004103) |
0.1 | 0.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.1 | 3.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.1 | 2.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.3 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.0 | 0.3 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.0 | 0.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.0 | 0.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.6 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.4 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.6 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
0.0 | 1.7 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 1.1 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 2.8 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.0 | 0.4 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.0 | 0.4 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.7 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 0.5 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.7 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 2.8 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 0.6 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 0.4 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.4 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.0 | 0.2 | REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL | Genes involved in NF-kB is activated and signals survival |
0.0 | 0.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.6 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.1 | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
0.0 | 0.3 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.3 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |