Motif ID: Cux1

Z-value: 0.768


Transcription factors associated with Cux1:

Gene SymbolEntrez IDGene Name
Cux1 ENSMUSG00000029705.11 Cux1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cux1mm10_v2_chr5_-_136565432_1365655300.513.2e-02Click!


Activity profile for motif Cux1.

activity profile for motif Cux1


Sorted Z-values histogram for motif Cux1

Sorted Z-values for motif Cux1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cux1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_96210107 1.614 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr5_+_117841839 1.606 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr2_+_71528657 1.432 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr7_-_103827922 1.252 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr2_+_71529085 1.207 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr5_+_66968961 1.124 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr5_-_122050102 1.114 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr17_-_6449571 1.100 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr5_+_66968559 1.072 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chrX_-_94212638 1.009 ENSMUST00000113922.1
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr8_+_12385769 0.985 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr4_+_119814495 0.936 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr16_-_4003750 0.936 ENSMUST00000171658.1
ENSMUST00000171762.1
Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

chr14_+_121035194 0.879 ENSMUST00000135010.1
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_66386968 0.877 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr5_-_145201829 0.875 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr7_+_25268387 0.804 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr7_-_74013676 0.767 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr7_-_19166119 0.760 ENSMUST00000094790.3
Gipr
gastric inhibitory polypeptide receptor
chr15_-_67113909 0.753 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr8_-_8639363 0.740 ENSMUST00000152698.1
Efnb2
ephrin B2
chr11_+_69095217 0.739 ENSMUST00000101004.2
Per1
period circadian clock 1
chr13_-_30974023 0.734 ENSMUST00000021785.6
Exoc2
exocyst complex component 2
chr2_+_158610731 0.663 ENSMUST00000045738.4
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr1_+_165302625 0.658 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chr9_+_111271832 0.654 ENSMUST00000060711.5
Epm2aip1
EPM2A (laforin) interacting protein 1
chr19_-_8819278 0.635 ENSMUST00000088092.5
Ttc9c
tetratricopeptide repeat domain 9C
chr4_-_119492563 0.600 ENSMUST00000049994.7
Rimkla
ribosomal modification protein rimK-like family member A
chr1_+_179546303 0.599 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr16_+_29579347 0.597 ENSMUST00000038867.6
ENSMUST00000161186.1
Opa1

optic atrophy 1

chr7_-_140154712 0.574 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr1_+_72583245 0.555 ENSMUST00000145868.1
ENSMUST00000133123.1
ENSMUST00000047615.8
Smarcal1


SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1


chr4_-_42034726 0.552 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr1_-_119837613 0.538 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr13_+_24614608 0.529 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr1_+_34005872 0.527 ENSMUST00000182296.1
Dst
dystonin
chr12_+_105453831 0.523 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chr7_+_44384604 0.514 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III

chr18_+_37447641 0.508 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr5_+_110544326 0.506 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr10_+_67096456 0.500 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr17_-_45686899 0.489 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chrX_+_136741821 0.484 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr15_+_21111452 0.483 ENSMUST00000075132.6
Cdh12
cadherin 12
chr4_-_62360524 0.465 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr6_+_41605482 0.460 ENSMUST00000114732.2
Ephb6
Eph receptor B6
chr13_-_66852017 0.460 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr16_-_91597636 0.460 ENSMUST00000023686.8
Tmem50b
transmembrane protein 50B
chr19_+_8819401 0.453 ENSMUST00000096753.3
Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr7_+_44590886 0.451 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr1_-_83408190 0.441 ENSMUST00000160953.1
Sphkap
SPHK1 interactor, AKAP domain containing
chr3_+_89715016 0.441 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr9_-_40346290 0.433 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr13_+_43615710 0.430 ENSMUST00000059986.2
Rnf182
ring finger protein 182
chr9_-_112232449 0.425 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr11_-_106487833 0.424 ENSMUST00000106801.1
Ern1
endoplasmic reticulum (ER) to nucleus signalling 1
chr17_-_85090204 0.421 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr6_-_97617536 0.421 ENSMUST00000113355.2
Frmd4b
FERM domain containing 4B
chr8_-_22694061 0.419 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr18_-_38211957 0.403 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr18_+_37484955 0.398 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr7_+_7171330 0.395 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr5_+_3596066 0.392 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr15_+_25758755 0.389 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr2_-_114175274 0.389 ENSMUST00000102543.4
Aqr
aquarius
chr1_-_119837338 0.387 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr13_-_110280103 0.385 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr8_-_4217133 0.381 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr17_-_87797994 0.381 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr1_+_179961110 0.381 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr2_+_30982350 0.381 ENSMUST00000061544.4
ENSMUST00000138161.1
ENSMUST00000142232.1
Usp20


ubiquitin specific peptidase 20


chr2_+_102706356 0.379 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr4_+_133369702 0.377 ENSMUST00000030669.7
Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr2_+_22622183 0.375 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr7_+_44384803 0.369 ENSMUST00000120262.1
Syt3
synaptotagmin III
chr10_-_127121125 0.365 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chrX_-_20950597 0.364 ENSMUST00000009550.7
Elk1
ELK1, member of ETS oncogene family
chr9_-_112185726 0.363 ENSMUST00000160240.1
ENSMUST00000162065.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr11_+_75486813 0.359 ENSMUST00000018449.4
ENSMUST00000102510.1
ENSMUST00000131283.1
Prpf8


pre-mRNA processing factor 8


chr2_-_167060417 0.356 ENSMUST00000155281.1
Znfx1
zinc finger, NFX1-type containing 1
chr10_-_32890462 0.355 ENSMUST00000092602.1
Nkain2
Na+/K+ transporting ATPase interacting 2
chrX_+_152233228 0.351 ENSMUST00000112588.2
ENSMUST00000082177.6
Kdm5c

lysine (K)-specific demethylase 5C

chr7_+_46033698 0.350 ENSMUST00000033121.6
Nomo1
nodal modulator 1
chr7_-_28962223 0.349 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr2_+_178414512 0.348 ENSMUST00000094251.4
Fam217b
family with sequence similarity 217, member B
chr6_+_48395652 0.345 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr10_+_103367748 0.344 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr1_-_84935089 0.343 ENSMUST00000027422.5
Slc16a14
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr11_-_60352869 0.343 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chr15_-_78120011 0.340 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr4_+_148448605 0.337 ENSMUST00000103221.3
ENSMUST00000057580.7
Mtor

mechanistic target of rapamycin (serine/threonine kinase)

chr1_+_34801704 0.336 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr8_-_77610668 0.336 ENSMUST00000141202.1
ENSMUST00000152168.1
Tmem184c

transmembrane protein 184C

chr4_+_42035113 0.335 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr6_-_40436104 0.334 ENSMUST00000039008.6
ENSMUST00000101492.3
E330009J07Rik

RIKEN cDNA E330009J07 gene

chr13_-_23368969 0.327 ENSMUST00000152557.1
Zfp322a
zinc finger protein 322A
chr8_-_73353477 0.324 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr11_+_71019859 0.324 ENSMUST00000155236.1
ENSMUST00000143762.1
ENSMUST00000136137.1
Mis12


MIS12 homolog (yeast)


chr4_-_155869394 0.324 ENSMUST00000105586.1
ENSMUST00000030950.1
Gltpd1

glycolipid transfer protein domain containing 1

chr8_+_85037151 0.324 ENSMUST00000166592.1
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr11_+_115765420 0.322 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene



chr1_-_183297256 0.322 ENSMUST00000163528.2
Brox
BRO1 domain and CAAX motif containing
chr11_-_42182924 0.321 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr2_+_164074122 0.320 ENSMUST00000018353.7
Stk4
serine/threonine kinase 4
chrY_+_90755657 0.318 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr2_+_128967383 0.318 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr7_+_12965831 0.315 ENSMUST00000038701.7
Zfp324
zinc finger protein 324
chr5_+_134099704 0.315 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr7_-_28372597 0.310 ENSMUST00000144700.1
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr2_+_131909951 0.309 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr1_-_135688094 0.307 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr9_-_21312255 0.307 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr13_+_44729535 0.307 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr9_-_112185939 0.305 ENSMUST00000070218.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr11_-_116198701 0.297 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_97744659 0.297 ENSMUST00000018691.8
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr16_+_29579331 0.296 ENSMUST00000160597.1
Opa1
optic atrophy 1
chr7_+_44384098 0.294 ENSMUST00000118962.1
ENSMUST00000118831.1
Syt3

synaptotagmin III

chr6_+_48554776 0.294 ENSMUST00000114545.1
ENSMUST00000153222.1
ENSMUST00000101436.2
Lrrc61


leucine rich repeat containing 61


chr3_+_88607742 0.294 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chrX_+_74309089 0.292 ENSMUST00000130581.1
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr14_+_48446128 0.291 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr14_+_68083853 0.290 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr1_+_75436002 0.288 ENSMUST00000131545.1
ENSMUST00000141124.1
Gmppa

GDP-mannose pyrophosphorylase A

chr11_-_70410010 0.287 ENSMUST00000019065.3
ENSMUST00000135148.1
Pelp1

proline, glutamic acid and leucine rich protein 1

chr19_+_60755947 0.287 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr6_+_48395586 0.285 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
Krba1


KRAB-A domain containing 1


chrM_+_9870 0.284 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr11_-_96916366 0.283 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr3_-_88772578 0.280 ENSMUST00000090945.4
Syt11
synaptotagmin XI
chr2_+_131909928 0.279 ENSMUST00000091288.6
Prnp
prion protein
chr11_+_32286946 0.278 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr2_-_92434027 0.277 ENSMUST00000111278.1
ENSMUST00000090559.5
Cry2

cryptochrome 2 (photolyase-like)

chr17_-_6782775 0.274 ENSMUST00000064234.6
Ezr
ezrin
chr15_+_12824815 0.271 ENSMUST00000169061.1
Drosha
drosha, ribonuclease type III
chr1_+_91053422 0.270 ENSMUST00000097650.3
ENSMUST00000068167.6
ENSMUST00000097649.3
Lrrfip1


leucine rich repeat (in FLII) interacting protein 1


chr3_-_53657339 0.269 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr3_-_63964659 0.267 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chrX_-_7947763 0.267 ENSMUST00000154244.1
Hdac6
histone deacetylase 6
chr14_-_75754475 0.267 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr15_+_76660564 0.266 ENSMUST00000004294.10
Kifc2
kinesin family member C2
chr7_+_141461728 0.264 ENSMUST00000167491.1
ENSMUST00000165194.1
Efcab4a

EF-hand calcium binding domain 4A

chr15_+_12824841 0.263 ENSMUST00000090292.5
Drosha
drosha, ribonuclease type III
chr11_-_6200411 0.262 ENSMUST00000066496.3
Nudcd3
NudC domain containing 3
chr1_-_24612700 0.261 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrX_+_101274023 0.260 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr11_-_78497734 0.259 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr3_+_98013503 0.258 ENSMUST00000079812.6
Notch2
notch 2
chr17_-_32822200 0.255 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr11_-_106487796 0.252 ENSMUST00000001059.2
ENSMUST00000106799.1
ENSMUST00000106800.1
Ern1


endoplasmic reticulum (ER) to nucleus signalling 1


chr3_-_129755305 0.248 ENSMUST00000029653.2
Egf
epidermal growth factor
chr2_-_178414460 0.247 ENSMUST00000058678.4
Ppp1r3d
protein phosphatase 1, regulatory subunit 3D
chr4_+_148039097 0.247 ENSMUST00000141283.1
Mthfr
5,10-methylenetetrahydrofolate reductase
chr9_+_114731177 0.246 ENSMUST00000035007.8
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr4_-_62360436 0.245 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr6_-_88875035 0.243 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr5_+_115565254 0.243 ENSMUST00000064454.7
Gcn1l1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr14_+_70077375 0.242 ENSMUST00000035908.1
Egr3
early growth response 3
chr9_+_56418624 0.240 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr1_+_132477361 0.240 ENSMUST00000027700.8
Rbbp5
retinoblastoma binding protein 5
chr9_+_54764748 0.240 ENSMUST00000034830.8
Crabp1
cellular retinoic acid binding protein I
chr2_+_153291404 0.237 ENSMUST00000028977.6
Kif3b
kinesin family member 3B
chr7_-_35215248 0.236 ENSMUST00000118444.1
ENSMUST00000122409.1
Lrp3

low density lipoprotein receptor-related protein 3

chr8_-_111027752 0.236 ENSMUST00000040241.8
Ddx19b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
chr1_-_77515048 0.233 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr2_-_165388245 0.232 ENSMUST00000103084.3
Zfp334
zinc finger protein 334
chr3_+_99141068 0.232 ENSMUST00000004343.2
Wars2
tryptophanyl tRNA synthetase 2 (mitochondrial)
chr11_-_86757483 0.231 ENSMUST00000060766.9
ENSMUST00000103186.4
Cltc

clathrin, heavy polypeptide (Hc)

chr15_+_84232030 0.229 ENSMUST00000023072.6
Parvb
parvin, beta
chr5_+_107437908 0.227 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr7_-_99695809 0.225 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr15_+_80287234 0.223 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr10_-_25200110 0.220 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr1_+_87404916 0.218 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr5_-_34288318 0.218 ENSMUST00000094868.3
Zfyve28
zinc finger, FYVE domain containing 28
chr8_-_54724317 0.218 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr11_-_96916407 0.216 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_+_29309429 0.215 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr3_-_85722474 0.213 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr6_+_71831441 0.210 ENSMUST00000171057.1
Immt
inner membrane protein, mitochondrial
chr11_+_69088490 0.209 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr15_-_37791993 0.208 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr10_+_81628570 0.207 ENSMUST00000153573.1
ENSMUST00000119336.1
Ankrd24

ankyrin repeat domain 24

chr19_-_46395722 0.207 ENSMUST00000040270.4
Actr1a
ARP1 actin-related protein 1A, centractin alpha
chr6_-_114969986 0.207 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)
chr18_+_77185979 0.205 ENSMUST00000075290.6
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr1_-_74588117 0.203 ENSMUST00000066986.6
Zfp142
zinc finger protein 142
chr4_+_120854786 0.203 ENSMUST00000071093.2
Rims3
regulating synaptic membrane exocytosis 3
chr11_+_120713919 0.198 ENSMUST00000026139.7
ENSMUST00000151852.1
Lrrc45

leucine rich repeat containing 45

chr11_-_65162904 0.197 ENSMUST00000093002.5
ENSMUST00000047463.8
Arhgap44

Rho GTPase activating protein 44

chr1_-_183297008 0.195 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr19_-_57360668 0.194 ENSMUST00000181921.1
B230217O12Rik
RIKEN cDNA B230217O12 gene
chr17_-_33760306 0.193 ENSMUST00000173860.1
Rab11b
RAB11B, member RAS oncogene family
chr2_+_178118975 0.193 ENSMUST00000108917.1
Phactr3
phosphatase and actin regulator 3
chr11_+_74649462 0.192 ENSMUST00000092915.5
ENSMUST00000117818.1
Cluh

clustered mitochondria (cluA/CLU1) homolog

chr4_-_118179628 0.191 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr19_-_8819314 0.190 ENSMUST00000096751.4
Ttc9c
tetratricopeptide repeat domain 9C
chr9_-_58204310 0.187 ENSMUST00000114144.2
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_+_21337828 0.187 ENSMUST00000034697.7
Slc44a2
solute carrier family 44, member 2
chr12_+_64917901 0.185 ENSMUST00000058135.4
Gm527
predicted gene 527

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.5 1.6 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 0.9 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.3 1.1 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.2 0.6 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 1.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.7 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.3 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735) regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.7 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.3 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.3 GO:1900041 intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.1 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.3 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.1 GO:0060558 regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.1 0.4 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.2 GO:0016115 terpenoid catabolic process(GO:0016115)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.1 0.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.2 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0007262 STAT protein import into nucleus(GO:0007262) negative regulation of cholesterol efflux(GO:0090370) regulation of hyaluronan biosynthetic process(GO:1900125) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 1.1 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0035844 positive regulation of polarized epithelial cell differentiation(GO:0030862) cloaca development(GO:0035844)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.2 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.8 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.0 0.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.3 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 2.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.5 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.7 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 1.3 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.7 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.2 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.9 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.3 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.3 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.6 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.4 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.5 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.8 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.5 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)