Motif ID: Atf7_E4f1

Z-value: 1.561

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf7mm10_v2_chr15_-_102529025_102529025-0.743.9e-04Click!
E4f1mm10_v2_chr17_-_24455265_24455345-0.551.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_106458440 7.805 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr6_-_23248264 6.742 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr3_+_67374116 5.764 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr13_-_23761223 5.566 ENSMUST00000102964.2
Hist1h4a
histone cluster 1, H4a
chr3_+_67374091 5.289 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr1_+_74791516 5.274 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr9_-_20976762 4.618 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr13_+_23531044 4.313 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr12_-_69159109 4.128 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr3_-_36571952 4.054 ENSMUST00000029270.3
Ccna2
cyclin A2
chr11_-_84525514 3.898 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr11_+_84525669 3.897 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr12_+_112644828 3.787 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chr8_+_116921735 3.720 ENSMUST00000034205.4
Cenpn
centromere protein N
chr7_-_137314394 3.613 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr17_-_36958437 3.603 ENSMUST00000113669.2
Znrd1
zinc ribbon domain containing, 1
chr4_+_141301228 3.582 ENSMUST00000006614.2
Epha2
Eph receptor A2
chr4_+_111720187 3.552 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr4_-_97584605 3.523 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr17_-_36958206 3.469 ENSMUST00000172823.1
Znrd1
zinc ribbon domain containing, 1
chrX_-_60893430 3.398 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_-_97584612 3.394 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_+_45718121 3.367 ENSMUST00000135500.2
Rpl18
ribosomal protein L18
chr17_+_36958623 3.367 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr17_+_34982154 3.316 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_+_84525647 3.312 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr10_+_121033960 3.311 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr11_+_69324069 3.305 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr1_+_95313607 3.300 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr9_-_96478660 3.287 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr17_-_71526819 3.257 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_+_89459118 3.254 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr13_+_8885501 3.238 ENSMUST00000169314.2
Idi1
isopentenyl-diphosphate delta isomerase
chr15_+_34238026 3.186 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr11_+_69324055 3.170 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr17_+_34982099 3.164 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_-_36958533 3.158 ENSMUST00000172518.1
Znrd1
zinc ribbon domain containing, 1
chr17_-_31277327 3.133 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr3_+_40800054 3.131 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr7_-_144939823 3.069 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr3_-_127553233 3.053 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr8_+_92674289 3.052 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr11_-_78165521 3.052 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr7_+_3703979 2.995 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr10_-_30200492 2.991 ENSMUST00000099985.4
Cenpw
centromere protein W
chr17_+_36958571 2.982 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr11_-_6444352 2.904 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr9_-_96478596 2.857 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr11_+_69323963 2.844 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr7_+_45718058 2.841 ENSMUST00000072503.6
Rpl18
ribosomal protein L18
chr10_+_79682169 2.749 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chr15_-_50889691 2.720 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr11_+_101468164 2.709 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr8_+_45885479 2.704 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr7_-_118533298 2.665 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr17_+_34981847 2.653 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_50566535 2.629 ENSMUST00000161401.1
Cycs
cytochrome c, somatic
chr4_+_130360132 2.517 ENSMUST00000105994.3
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr7_-_38271310 2.489 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr12_+_79130777 2.463 ENSMUST00000021550.6
Arg2
arginase type II
chr7_+_3704307 2.420 ENSMUST00000108624.1
ENSMUST00000126562.1
Rps9

ribosomal protein S9

chr10_+_96616998 2.406 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr8_+_92674826 2.364 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chrX_+_106187100 2.364 ENSMUST00000081593.6
Pgk1
phosphoglycerate kinase 1
chr12_+_108792946 2.363 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr10_-_128176568 2.333 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr11_-_88718223 2.276 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr2_+_105668888 2.262 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr3_+_89459325 2.250 ENSMUST00000107410.1
Pmvk
phosphomevalonate kinase
chr7_+_139389072 2.232 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr7_+_3704025 2.219 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr3_-_146108047 2.203 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr5_+_142960343 2.166 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr11_+_22990519 2.120 ENSMUST00000173867.1
ENSMUST00000020562.4
Cct4

chaperonin containing Tcp1, subunit 4 (delta)

chr4_-_134245579 2.079 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr11_+_59208321 2.045 ENSMUST00000020719.6
2310033P09Rik
RIKEN cDNA 2310033P09 gene
chr8_-_84662841 2.031 ENSMUST00000060427.4
Ier2
immediate early response 2
chr1_-_71653162 2.029 ENSMUST00000055226.6
Fn1
fibronectin 1
chr16_-_23890805 2.024 ENSMUST00000004480.3
Sst
somatostatin
chr19_+_59260878 1.997 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr5_+_114444266 1.997 ENSMUST00000043760.8
ENSMUST00000112239.2
ENSMUST00000125650.1
Mvk


mevalonate kinase


chr11_-_69980468 1.996 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr15_+_99074968 1.986 ENSMUST00000039665.6
Troap
trophinin associated protein
chr13_+_8885937 1.983 ENSMUST00000177397.1
ENSMUST00000177400.1
ENSMUST00000177447.1
Idi1


isopentenyl-diphosphate delta isomerase


chr4_-_131838231 1.982 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr10_+_80141457 1.976 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr13_-_64274879 1.964 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr8_-_92355764 1.933 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr2_-_132253227 1.929 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr4_+_3938888 1.909 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr2_-_57114970 1.901 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr10_+_44268328 1.893 ENSMUST00000039286.4
Atg5
autophagy related 5
chr1_-_92473801 1.861 ENSMUST00000027478.6
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
chr1_+_92831614 1.840 ENSMUST00000045970.6
Gpc1
glypican 1
chr3_+_135212557 1.824 ENSMUST00000062893.7
Cenpe
centromere protein E
chr11_+_76243715 1.805 ENSMUST00000040577.4
Rnmtl1
RNA methyltransferase like 1
chr11_-_76243687 1.777 ENSMUST00000017430.5
Glod4
glyoxalase domain containing 4
chrX_+_112311334 1.770 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr11_-_76243610 1.768 ENSMUST00000164022.1
ENSMUST00000168055.1
ENSMUST00000169701.1
Glod4


glyoxalase domain containing 4


chr15_+_79516396 1.767 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr18_+_82914632 1.767 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr1_-_134079114 1.738 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr17_+_23679363 1.736 ENSMUST00000024699.2
Cldn6
claudin 6
chr12_+_52097737 1.723 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr1_+_175880775 1.699 ENSMUST00000039725.6
Exo1
exonuclease 1
chr11_-_69920892 1.695 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr13_-_22042949 1.683 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr17_-_31658729 1.682 ENSMUST00000166526.1
ENSMUST00000014684.4
U2af1

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1

chr2_+_164746028 1.659 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr9_+_48495345 1.658 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr6_-_49264014 1.649 ENSMUST00000031841.7
Tra2a
transformer 2 alpha homolog (Drosophila)
chr13_+_22043189 1.632 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr2_+_164745979 1.616 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr2_-_127133909 1.613 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr11_-_69921057 1.592 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr18_+_11657349 1.574 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chr11_+_64435315 1.554 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr8_-_22653406 1.543 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr17_+_72918298 1.535 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr5_-_110653348 1.521 ENSMUST00000042147.5
Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr19_-_4625612 1.495 ENSMUST00000025823.3
Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr4_-_123750236 1.453 ENSMUST00000102636.3
Akirin1
akirin 1
chr3_-_45378206 1.443 ENSMUST00000181047.1
2610316D01Rik
RIKEN cDNA 2610316D01 gene
chr11_+_52232183 1.440 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr11_+_40733639 1.429 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr11_-_97629685 1.429 ENSMUST00000052281.4
E130012A19Rik
RIKEN cDNA E130012A19 gene
chr7_+_102441685 1.427 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr10_-_128493834 1.424 ENSMUST00000164181.1
Myl6
myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
chr18_+_66458587 1.420 ENSMUST00000025399.7
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr8_-_70873477 1.419 ENSMUST00000007865.5
Ccdc124
coiled-coil domain containing 124
chr5_+_9100681 1.388 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr7_-_118584669 1.376 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr11_-_97782377 1.367 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr11_-_69921190 1.366 ENSMUST00000108607.1
Eif5a
eukaryotic translation initiation factor 5A
chr7_+_82867327 1.359 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr7_+_141447645 1.350 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr8_-_92356103 1.346 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr7_-_25250720 1.346 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr11_-_97782409 1.343 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr7_-_13034722 1.332 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr11_+_40733936 1.330 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr13_-_30545254 1.317 ENSMUST00000042834.3
Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr7_-_105744312 1.306 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_-_70237852 1.306 ENSMUST00000108575.2
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr6_+_135065651 1.304 ENSMUST00000050104.7
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr19_-_5085483 1.304 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr17_-_27907706 1.302 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chrX_-_8145713 1.280 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr5_-_125389177 1.273 ENSMUST00000108707.2
Ubc
ubiquitin C
chr4_-_117182623 1.269 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr17_+_84511832 1.262 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr5_+_125389284 1.243 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr4_+_155704789 1.236 ENSMUST00000030905.2
Ssu72
Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
chr4_+_3938904 1.235 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr7_-_30664986 1.228 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr14_+_47472547 1.222 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr11_+_69965396 1.220 ENSMUST00000018713.6
Cldn7
claudin 7
chr14_+_47472628 1.211 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr11_-_70237886 1.189 ENSMUST00000108577.1
ENSMUST00000108579.1
ENSMUST00000021181.6
ENSMUST00000108578.2
ENSMUST00000102569.3
0610010K14Rik




RIKEN cDNA 0610010K14 gene




chr8_+_72135247 1.188 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr9_-_103364970 1.188 ENSMUST00000116517.2
Cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chrX_+_74254782 1.181 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr11_+_100320596 1.177 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr19_+_6057925 1.169 ENSMUST00000179142.1
Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr10_+_72654873 1.162 ENSMUST00000105431.1
ENSMUST00000160337.1
Zwint

ZW10 interactor

chr17_+_53479212 1.161 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family
chr2_+_109280738 1.157 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr11_-_69921329 1.150 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
Eif5a


eukaryotic translation initiation factor 5A


chr5_-_5559521 1.139 ENSMUST00000088842.4
ENSMUST00000115441.2
Gtpbp10

GTP-binding protein 10 (putative)

chr8_+_79711792 1.137 ENSMUST00000048147.7
Anapc10
anaphase promoting complex subunit 10
chr11_+_110968056 1.133 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr16_-_4077778 1.131 ENSMUST00000006137.8
Trap1
TNF receptor-associated protein 1
chr10_+_13008442 1.117 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr19_+_6057888 1.108 ENSMUST00000043074.5
ENSMUST00000178310.1
Fau

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

chr17_-_33824346 1.107 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr3_+_103171655 1.104 ENSMUST00000005830.8
Bcas2
breast carcinoma amplified sequence 2
chr11_-_70237761 1.103 ENSMUST00000108576.3
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr13_-_64274962 1.092 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr3_-_138143352 1.086 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr11_-_69323768 1.080 ENSMUST00000092973.5
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr9_+_64179289 1.078 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr17_+_35979851 1.067 ENSMUST00000087200.3
Gnl1
guanine nucleotide binding protein-like 1
chr6_+_124931378 1.066 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr6_-_131293187 1.065 ENSMUST00000032307.5
Magohb
mago-nashi homolog B (Drosophila)
chr8_-_80739497 1.060 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_+_105668935 1.055 ENSMUST00000142772.1
Pax6
paired box gene 6
chr2_+_156065180 1.050 ENSMUST00000038860.5
Spag4
sperm associated antigen 4
chr16_+_38562806 1.050 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr11_-_70237638 1.044 ENSMUST00000100950.3
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr5_-_108434373 1.043 ENSMUST00000049628.9
ENSMUST00000118632.1
Atp5k

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

chr4_-_117156144 1.036 ENSMUST00000102696.4
Rps8
ribosomal protein S8
chr3_+_40800013 1.011 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr16_-_4790220 1.010 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr12_+_102743750 1.009 ENSMUST00000057416.6
Tmem251
transmembrane protein 251
chr10_+_72654845 1.001 ENSMUST00000020081.4
Zwint
ZW10 interactor
chr16_-_33967032 0.968 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chrM_+_5319 0.965 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr16_-_16829276 0.954 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr11_+_113619318 0.946 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr1_+_38987806 0.941 ENSMUST00000027247.5
Pdcl3
phosducin-like 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.7 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.9 7.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.7 10.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
1.3 1.3 GO:1903722 regulation of centriole elongation(GO:1903722)
1.3 3.9 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.3 3.9 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
1.2 3.6 GO:0014028 notochord formation(GO:0014028)
1.1 6.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.1 6.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.9 4.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.9 5.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.8 3.2 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.8 9.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 2.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.7 2.7 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.7 3.3 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.6 1.9 GO:0035973 aggrephagy(GO:0035973)
0.6 2.5 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.6 1.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.6 4.1 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.6 5.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.6 2.8 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.5 2.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.5 10.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.5 6.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.5 1.6 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.5 5.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.5 1.9 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.5 3.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.5 1.9 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.5 5.2 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.5 5.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 3.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.4 2.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 2.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 4.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.4 1.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.4 1.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.4 2.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.4 1.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.4 1.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 0.7 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 2.0 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 1.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 1.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 1.3 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3 2.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 1.5 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.3 2.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.3 1.5 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.3 0.9 GO:0051030 snRNA transport(GO:0051030)
0.3 2.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 3.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 0.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 0.8 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.3 0.8 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.3 3.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.2 0.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 0.7 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 6.7 GO:0034508 centromere complex assembly(GO:0034508)
0.2 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 1.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 1.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.2 0.9 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 1.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 7.8 GO:0001709 cell fate determination(GO:0001709)
0.2 1.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.2 2.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.8 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 4.3 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.8 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.2 2.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 0.9 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.6 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.7 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 2.4 GO:0031639 plasminogen activation(GO:0031639)
0.2 0.9 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 2.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 3.7 GO:0007530 sex determination(GO:0007530)
0.2 1.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 1.2 GO:0051036 regulation of endosome size(GO:0051036)
0.2 0.5 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 2.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.4 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 1.4 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.4 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.5 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 4.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 1.6 GO:0042407 cristae formation(GO:0042407)
0.1 0.9 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 1.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.7 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.5 GO:0044828 negative regulation by host of viral process(GO:0044793) negative regulation by host of viral genome replication(GO:0044828)
0.1 0.8 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 3.8 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.9 GO:0030432 peristalsis(GO:0030432)
0.1 1.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 3.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.6 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.4 GO:0009597 detection of virus(GO:0009597)
0.1 3.8 GO:0009409 response to cold(GO:0009409)
0.1 0.3 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 2.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 1.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.5 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.9 GO:0006824 cobalt ion transport(GO:0006824)
0.1 1.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 3.1 GO:0035082 axoneme assembly(GO:0035082)
0.1 1.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 3.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 1.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 1.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 6.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 5.3 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.6 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 0.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.3 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.1 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.6 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.6 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 1.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 1.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.6 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 1.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 2.1 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 1.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.4 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0071028 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 1.8 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 8.3 GO:0006412 translation(GO:0006412)
0.0 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.1 GO:0070344 fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
0.0 5.6 GO:0008380 RNA splicing(GO:0008380)
0.0 2.0 GO:0048864 stem cell development(GO:0048864)
0.0 0.6 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 2.0 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.4 GO:0051591 response to cAMP(GO:0051591)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.3 9.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.8 3.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.7 4.1 GO:0098536 deuterosome(GO:0098536)
0.7 2.0 GO:0005577 fibrinogen complex(GO:0005577)
0.6 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 10.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.6 1.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.6 6.6 GO:0005642 annulate lamellae(GO:0005642)
0.6 9.3 GO:0030008 TRAPP complex(GO:0030008)
0.6 4.1 GO:0001940 male pronucleus(GO:0001940)
0.5 1.6 GO:0000799 nuclear condensin complex(GO:0000799)
0.5 2.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.5 3.3 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.4 2.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 5.7 GO:0016589 NURF complex(GO:0016589)
0.4 3.1 GO:0001520 outer dense fiber(GO:0001520)
0.4 1.5 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.4 1.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 17.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 9.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.5 GO:0030689 Noc complex(GO:0030689)
0.3 12.1 GO:0097546 ciliary base(GO:0097546)
0.3 1.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 1.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 2.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 2.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.3 GO:0000125 PCAF complex(GO:0000125)
0.2 0.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 1.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.6 GO:0070652 HAUS complex(GO:0070652)
0.2 1.8 GO:0061617 MICOS complex(GO:0061617)
0.2 1.7 GO:0089701 U2AF(GO:0089701)
0.2 0.9 GO:1990246 uniplex complex(GO:1990246)
0.2 2.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 2.2 GO:0071437 invadopodium(GO:0071437)
0.2 1.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 1.1 GO:0000796 condensin complex(GO:0000796)
0.2 4.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 2.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.4 GO:0031011 Ino80 complex(GO:0031011)
0.2 1.1 GO:0033503 HULC complex(GO:0033503)
0.2 2.6 GO:0031045 dense core granule(GO:0031045)
0.1 10.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.5 GO:0097447 dendritic tree(GO:0097447)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 3.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 3.6 GO:0044815 DNA packaging complex(GO:0044815)
0.1 1.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.3 GO:0042827 platelet dense granule(GO:0042827)
0.1 3.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 4.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 9.7 GO:0000776 kinetochore(GO:0000776)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 12.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 3.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.1 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 2.2 GO:0030286 dynein complex(GO:0030286)
0.1 0.4 GO:0034709 methylosome(GO:0034709)
0.1 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.3 GO:0005844 polysome(GO:0005844)
0.1 0.8 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 3.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 8.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 7.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.0 GO:0031514 motile cilium(GO:0031514)
0.0 2.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0005840 ribosome(GO:0005840)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.4 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.8 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.8 2.5 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.8 6.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 3.6 GO:0032027 myosin light chain binding(GO:0032027)
0.7 10.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.7 2.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.6 1.9 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.6 1.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.6 1.8 GO:0070052 collagen V binding(GO:0070052)
0.6 2.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.5 4.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 2.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.5 3.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 1.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.5 2.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 5.5 GO:0001618 virus receptor activity(GO:0001618)
0.4 1.7 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.4 6.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 2.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 5.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4 9.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 1.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.4 1.8 GO:0043515 kinetochore binding(GO:0043515)
0.3 2.0 GO:0045340 mercury ion binding(GO:0045340)
0.3 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.2 GO:0042731 PH domain binding(GO:0042731)
0.3 1.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 0.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 3.1 GO:0031996 thioesterase binding(GO:0031996)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.7 GO:0050733 RS domain binding(GO:0050733)
0.2 1.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.2 2.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 1.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 0.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 3.3 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.6 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 3.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 3.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 3.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 1.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 7.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 1.5 GO:0032564 dATP binding(GO:0032564)
0.2 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 0.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 5.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.6 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 2.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 5.6 GO:0005109 frizzled binding(GO:0005109)
0.1 3.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.4 GO:0030519 snoRNP binding(GO:0030519)
0.1 21.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 6.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 2.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 5.5 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 3.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 3.6 GO:0009055 electron carrier activity(GO:0009055)
0.1 1.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 2.0 GO:0019843 rRNA binding(GO:0019843)
0.1 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 3.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 1.4 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 9.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 2.7 GO:0004497 monooxygenase activity(GO:0004497)
0.0 3.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 2.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 2.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 5.4 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 1.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.3 GO:0002020 protease binding(GO:0002020)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.0 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 3.9 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 2.8 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.6 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 6.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 4.2 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.3 ST_STAT3_PATHWAY STAT3 Pathway
0.1 3.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.7 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 3.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.6 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 5.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 1.3 PID_MYC_PATHWAY C-MYC pathway
0.1 2.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.6 PID_FOXO_PATHWAY FoxO family signaling
0.1 2.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.9 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID_CASPASE_PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 12.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 12.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.3 17.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 6.6 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 4.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 2.0 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 1.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 4.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 10.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 2.0 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.5 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.6 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.5 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 3.2 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.2 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 3.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 2.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 7.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 3.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.3 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 4.6 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 8.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.6 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 5.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.1 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.1 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.9 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 2.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 7.7 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 5.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.8 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.6 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 2.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 3.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis