Motif ID: Pitx3
Z-value: 0.967

Transcription factors associated with Pitx3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pitx3 | ENSMUSG00000025229.9 | Pitx3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 4.1 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.7 | 2.0 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
0.7 | 2.0 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
0.6 | 3.1 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.6 | 1.8 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.6 | 3.4 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.5 | 2.4 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.4 | 1.5 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
0.3 | 1.0 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170) |
0.3 | 2.4 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
0.3 | 0.9 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
0.3 | 0.9 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.3 | 1.4 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
0.3 | 0.8 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.3 | 1.3 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
0.3 | 0.8 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
0.3 | 1.3 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.2 | 1.2 | GO:0044838 | cell quiescence(GO:0044838) |
0.2 | 0.8 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.2 | 0.6 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.2 | 0.6 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045) |
0.2 | 0.6 | GO:0018094 | protein polyglycylation(GO:0018094) |
0.2 | 0.9 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.2 | 1.0 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
0.2 | 0.5 | GO:0002925 | regulation of dendritic cell cytokine production(GO:0002730) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) detection of peptidoglycan(GO:0032499) negative regulation of interleukin-18 production(GO:0032701) |
0.2 | 0.7 | GO:0002677 | negative regulation of chronic inflammatory response(GO:0002677) |
0.2 | 0.6 | GO:1990743 | protein sialylation(GO:1990743) |
0.2 | 0.8 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 0.7 | GO:0021764 | amygdala development(GO:0021764) |
0.1 | 0.4 | GO:1905223 | epicardium morphogenesis(GO:1905223) |
0.1 | 0.8 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.1 | 0.4 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.1 | 1.1 | GO:0060613 | fat pad development(GO:0060613) |
0.1 | 0.6 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.1 | 0.4 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
0.1 | 1.8 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
0.1 | 0.3 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
0.1 | 0.5 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
0.1 | 0.6 | GO:1904953 | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) |
0.1 | 1.0 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.1 | 0.9 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.1 | 1.9 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
0.1 | 0.4 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.1 | 0.4 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.1 | 0.6 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
0.1 | 0.2 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.1 | 0.2 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
0.1 | 1.3 | GO:0045056 | transcytosis(GO:0045056) |
0.1 | 0.2 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
0.1 | 0.2 | GO:1900365 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365) |
0.1 | 0.1 | GO:0097694 | establishment of RNA localization to telomere(GO:0097694) |
0.1 | 0.4 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.1 | 0.6 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.2 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.1 | 1.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.1 | 0.4 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 0.8 | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
0.1 | 1.0 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
0.1 | 0.3 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.1 | 0.2 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.1 | 1.0 | GO:0097502 | mannosylation(GO:0097502) |
0.1 | 1.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 0.2 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
0.1 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.1 | 0.2 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
0.1 | 0.4 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 0.5 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.1 | 0.2 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.1 | 0.2 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
0.1 | 1.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.1 | 0.2 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.0 | 0.1 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.0 | 0.5 | GO:0033683 | nucleotide-excision repair, DNA incision(GO:0033683) |
0.0 | 0.2 | GO:0046874 | quinolinate metabolic process(GO:0046874) |
0.0 | 0.4 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.0 | 0.4 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.0 | 0.2 | GO:0048539 | bone marrow development(GO:0048539) replicative senescence(GO:0090399) |
0.0 | 4.1 | GO:0001824 | blastocyst development(GO:0001824) |
0.0 | 0.1 | GO:0002423 | natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) |
0.0 | 0.3 | GO:0008343 | adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.0 | 0.2 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
0.0 | 0.3 | GO:0033227 | dsRNA transport(GO:0033227) |
0.0 | 0.2 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.7 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.2 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.0 | 0.4 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.0 | 0.4 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.3 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
0.0 | 0.5 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
0.0 | 1.4 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.0 | 0.4 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.0 | 0.2 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.0 | 0.5 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.0 | 0.1 | GO:1902256 | endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) atrial septum primum morphogenesis(GO:0003289) negative regulation of alkaline phosphatase activity(GO:0010693) negative regulation of macrophage cytokine production(GO:0010936) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
0.0 | 0.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.1 | GO:0035878 | nail development(GO:0035878) |
0.0 | 0.6 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 1.1 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 0.1 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
0.0 | 0.1 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.0 | 0.2 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.0 | 0.2 | GO:0097475 | motor neuron migration(GO:0097475) |
0.0 | 0.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.1 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
0.0 | 0.1 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
0.0 | 0.4 | GO:0003094 | glomerular filtration(GO:0003094) |
0.0 | 0.1 | GO:0021972 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
0.0 | 0.1 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.0 | 0.2 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 1.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 0.3 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.0 | 0.1 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
0.0 | 0.1 | GO:0016237 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) modulation by virus of host autophagy(GO:0039519) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157) |
0.0 | 0.8 | GO:0051058 | negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.2 | GO:0003334 | keratinocyte development(GO:0003334) |
0.0 | 0.1 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
0.0 | 0.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 0.6 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.2 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
0.0 | 0.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.1 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
0.0 | 0.0 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.0 | 0.2 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.3 | GO:0031297 | replication fork processing(GO:0031297) |
0.0 | 1.5 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0000802 | transverse filament(GO:0000802) |
0.2 | 0.5 | GO:0035101 | FACT complex(GO:0035101) |
0.1 | 0.9 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.1 | 1.1 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
0.1 | 0.4 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.1 | 0.9 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.1 | 0.7 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 1.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 0.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 0.7 | GO:0002177 | manchette(GO:0002177) |
0.1 | 1.1 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.1 | 0.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 0.3 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 1.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.1 | 0.3 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 0.8 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.6 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 1.1 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.2 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.0 | 0.9 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.7 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 1.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.3 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
0.0 | 0.6 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.5 | GO:0033202 | DNA helicase complex(GO:0033202) |
0.0 | 2.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.3 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.0 | 0.3 | GO:0044754 | autolysosome(GO:0044754) |
0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.0 | 0.2 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.7 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 2.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.2 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.4 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
0.0 | 0.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.1 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.2 | GO:1904115 | axon cytoplasm(GO:1904115) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.4 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
0.7 | 2.0 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
0.5 | 3.1 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.5 | 1.5 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
0.4 | 2.0 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.4 | 1.1 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
0.3 | 0.9 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.3 | 0.8 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
0.3 | 1.6 | GO:0019841 | retinol binding(GO:0019841) |
0.2 | 1.3 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.2 | 0.6 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.2 | 0.6 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
0.2 | 0.6 | GO:0070736 | protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) |
0.2 | 2.0 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.2 | 0.7 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
0.2 | 0.9 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 1.1 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 0.7 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.1 | 1.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.1 | 1.3 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 0.5 | GO:0042834 | peptidoglycan binding(GO:0042834) |
0.1 | 0.7 | GO:0097001 | ceramide binding(GO:0097001) |
0.1 | 0.6 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.1 | 0.4 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.1 | 0.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.1 | 1.8 | GO:0030275 | LRR domain binding(GO:0030275) |
0.1 | 0.5 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
0.1 | 0.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.1 | 0.2 | GO:0036004 | GAF domain binding(GO:0036004) |
0.1 | 0.2 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.1 | 0.7 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.1 | 0.3 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.1 | 0.2 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
0.1 | 0.3 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.1 | 0.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.1 | 1.4 | GO:0042287 | MHC protein binding(GO:0042287) |
0.1 | 0.5 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.1 | 0.8 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 1.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 1.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.1 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.0 | 0.2 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
0.0 | 0.1 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
0.0 | 0.2 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
0.0 | 0.8 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.0 | 0.9 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 0.2 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.0 | 0.5 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 1.0 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 0.7 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
0.0 | 0.2 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.0 | 1.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.2 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.0 | 0.3 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
0.0 | 0.3 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
0.0 | 0.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.0 | 0.2 | GO:0098505 | single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) |
0.0 | 0.5 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.3 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.3 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 0.1 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
0.0 | 0.2 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
0.0 | 0.4 | GO:0005123 | death receptor binding(GO:0005123) |
0.0 | 0.2 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.0 | 0.1 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.0 | 0.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.5 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.9 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.9 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.1 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.4 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.1 | GO:0019779 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
0.0 | 0.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 0.0 | GO:0030172 | troponin C binding(GO:0030172) |
0.0 | 0.5 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 1.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.9 | GO:0034212 | peptide N-acetyltransferase activity(GO:0034212) |
0.0 | 0.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.1 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.5 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.2 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.0 | 0.4 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 3.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.3 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 1.5 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 0.8 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 1.3 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 0.6 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.7 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.6 | ST_GAQ_PATHWAY | G alpha q Pathway |
0.0 | 0.6 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.4 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.5 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 0.5 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 1.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.1 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 1.9 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.1 | 2.7 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 1.9 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.1 | 5.0 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 1.7 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 0.8 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 1.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.6 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 2.8 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 2.0 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 1.0 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.8 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.6 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 3.5 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.0 | 0.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.3 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.0 | 0.2 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.5 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
0.0 | 1.3 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.5 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.3 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
0.0 | 1.5 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.2 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 0.4 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 0.1 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 0.2 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.3 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |