Motif ID: Pitx3

Z-value: 0.967


Transcription factors associated with Pitx3:

Gene SymbolEntrez IDGene Name
Pitx3 ENSMUSG00000025229.9 Pitx3



Activity profile for motif Pitx3.

activity profile for motif Pitx3


Sorted Z-values histogram for motif Pitx3

Sorted Z-values for motif Pitx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_62899118 3.057 ENSMUST00000174189.1
Tet1
tet methylcytosine dioxygenase 1
chr16_+_17276291 2.852 ENSMUST00000164950.1
ENSMUST00000159242.1
Tmem191c

transmembrane protein 191C

chrX_+_7909542 2.301 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr11_-_79296906 2.257 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr6_+_90550789 2.015 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr5_+_90759299 2.007 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr11_-_100770926 1.872 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr5_+_138280538 1.707 ENSMUST00000162245.1
ENSMUST00000161691.1
Stag3

stromal antigen 3

chr2_+_28506095 1.699 ENSMUST00000074761.4
Gm10134
predicted gene 10134
chr7_-_79386943 1.607 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr1_+_85575676 1.589 ENSMUST00000178024.1
G530012D18Rik
RIKEN cDNA G530012D1 gene
chr10_+_81718919 1.536 ENSMUST00000085664.5
Zfp433
RIKEN cDNA 1700123A16 gene
chr17_-_32189457 1.529 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3

epoxide hydrolase 3

chrX_+_142226765 1.520 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr17_-_71460395 1.510 ENSMUST00000180522.1
Gm4707
predicted gene 4707
chr16_+_17276337 1.462 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
Tmem191c


transmembrane protein 191C


chr17_+_49428359 1.424 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
Mocs1


molybdenum cofactor synthesis 1


chr3_+_86070915 1.418 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr1_-_153408429 1.413 ENSMUST00000097535.4
E330020D12Rik
Riken cDNA E330020D12 gene
chr9_+_118506226 1.397 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr5_+_138280516 1.396 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr12_-_87775755 1.386 ENSMUST00000164517.2
Gm21319
predicted gene, 21319
chrX_-_103623648 1.368 ENSMUST00000156211.1
Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr9_-_15357692 1.367 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr8_+_65967157 1.363 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chr10_-_53379816 1.362 ENSMUST00000095691.5
Cep85l
centrosomal protein 85-like
chr2_+_127008711 1.353 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chr3_-_88456397 1.347 ENSMUST00000141471.1
ENSMUST00000123753.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr9_-_7836980 1.345 ENSMUST00000054878.5
C330006D17Rik
RIKEN cDNA C330006D17 gene
chrY_+_818646 1.336 ENSMUST00000115894.1
Uba1y
ubiquitin-activating enzyme, Chr Y
chr17_-_35188427 1.325 ENSMUST00000097336.4
Lst1
leukocyte specific transcript 1
chr8_+_69300776 1.325 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr16_-_38341812 1.302 ENSMUST00000114740.2
ENSMUST00000023501.8
Maats1

MYCBP-associated, testis expressed 1

chr4_+_138775735 1.299 ENSMUST00000030528.2
Pla2g2d
phospholipase A2, group IID
chr11_+_102041509 1.276 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
Cd300lg



CD300 antigen like family member G



chr7_-_81855794 1.276 ENSMUST00000085094.3
Gm10160
predicted gene 10160
chr13_-_67609617 1.268 ENSMUST00000138725.1
AA987161
expressed sequence AA987161
chr4_-_155645408 1.255 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr10_+_39612934 1.249 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr6_+_149130170 1.248 ENSMUST00000087348.3
Gm10203
predicted gene 10203
chr2_-_132578128 1.241 ENSMUST00000028822.7
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr7_+_18987518 1.239 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr11_+_67025144 1.237 ENSMUST00000079077.5
ENSMUST00000061786.5
Tmem220

transmembrane protein 220

chr11_-_100472725 1.233 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr5_+_3571664 1.154 ENSMUST00000008451.5
1700109H08Rik
RIKEN cDNA 1700109H08 gene
chr10_-_68278713 1.126 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr1_-_133701881 1.102 ENSMUST00000167348.1
Gm17678
predicted gene, 17678
chr2_-_132578244 1.099 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr13_-_100104064 1.097 ENSMUST00000038104.5
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr11_-_62457772 1.091 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr2_-_132578155 1.087 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr17_-_32800938 1.078 ENSMUST00000080905.6
Zfp811
zinc finger protein 811
chr11_+_105146893 1.075 ENSMUST00000100338.1
Gm10842
predicted gene 10842
chr19_+_7494033 1.072 ENSMUST00000170373.1
Atl3
atlastin GTPase 3
chr4_-_101844023 1.041 ENSMUST00000106919.1
B020004J07Rik
RIKEN cDNA B020004J07 gene
chrX_-_103623704 1.039 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr5_-_138155694 1.038 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr10_+_88459569 1.035 ENSMUST00000020252.3
ENSMUST00000125612.1
Sycp3

synaptonemal complex protein 3

chr7_-_80324418 1.031 ENSMUST00000047362.4
ENSMUST00000121882.1
Rccd1

RCC1 domain containing 1

chr10_-_86011833 1.025 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr5_-_143895025 1.008 ENSMUST00000079624.5
ENSMUST00000110717.2
Ankrd61

ankyrin repeat domain 61

chr12_-_85097080 1.008 ENSMUST00000177289.2
Prox2
prospero homeobox 2
chr13_-_77131276 1.003 ENSMUST00000159300.1
Ankrd32
ankyrin repeat domain 32
chr9_-_49798905 0.999 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr5_+_122643878 0.991 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr12_+_51348019 0.985 ENSMUST00000054308.6
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr17_-_6079693 0.958 ENSMUST00000024570.5
ENSMUST00000097432.3
Serac1

serine active site containing 1

chr13_-_67609667 0.957 ENSMUST00000012873.8
AA987161
expressed sequence AA987161
chr4_+_155812489 0.939 ENSMUST00000030944.4
Ccnl2
cyclin L2
chrX_+_9885622 0.930 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr8_-_129221950 0.929 ENSMUST00000079272.6
2610044O15Rik8
RIKEN cDNA 2610044O15 gene
chr9_-_89092835 0.928 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr19_-_61176309 0.924 ENSMUST00000180168.1
Gm7102
predicted gene 7102
chr15_+_99295087 0.923 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr12_+_51348265 0.922 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr2_-_156007919 0.919 ENSMUST00000086145.3
ENSMUST00000144686.1
ENSMUST00000140657.1
6430550D23Rik


RIKEN cDNA 6430550D23 gene


chr10_+_80702649 0.915 ENSMUST00000095426.3
Izumo4
IZUMO family member 4
chr12_+_51348370 0.911 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr7_-_45370559 0.903 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr1_-_39651165 0.901 ENSMUST00000053355.4
Creg2
cellular repressor of E1A-stimulated genes 2
chr17_+_35067317 0.891 ENSMUST00000173478.1
ENSMUST00000174876.1
Ly6g6c

lymphocyte antigen 6 complex, locus G6C

chr14_-_77036081 0.886 ENSMUST00000142300.1
Lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr17_+_94873986 0.884 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr10_+_111164794 0.876 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr13_-_23430826 0.875 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr17_+_56764738 0.872 ENSMUST00000007747.8
Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chrX_+_101640056 0.870 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr2_-_73312701 0.858 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr1_-_135167606 0.849 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr17_+_57769570 0.847 ENSMUST00000076038.5
Cntnap5c
contactin associated protein-like 5C
chr1_-_58586191 0.844 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chrX_+_159532655 0.840 ENSMUST00000112464.1
A830080D01Rik
RIKEN cDNA A830080D01 gene
chr7_+_24176152 0.832 ENSMUST00000086010.5
Zfp114
zinc finger protein 114
chr9_-_49798729 0.823 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr7_+_131410601 0.820 ENSMUST00000015829.7
ENSMUST00000117518.1
Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr10_-_62792243 0.808 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr13_-_12464925 0.807 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr4_-_101981049 0.805 ENSMUST00000106916.1
Gm12790
predicted gene 12790
chr14_+_66635251 0.805 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
Adra1a


adrenergic receptor, alpha 1a


chr14_-_20702991 0.802 ENSMUST00000180987.1
6230400D17Rik
RIKEN cDNA 6230400D17 gene
chr5_-_62766153 0.801 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_22307638 0.799 ENSMUST00000086278.6
Zfp810
zinc finger protein 810
chr17_+_24549950 0.798 ENSMUST00000035565.3
Pkd1
polycystic kidney disease 1 homolog
chr11_-_116131073 0.797 ENSMUST00000106440.2
ENSMUST00000067632.3
Trim65

tripartite motif-containing 65

chrX_-_36645359 0.795 ENSMUST00000051906.6
Akap17b
A kinase (PRKA) anchor protein 17B
chr18_-_10610346 0.773 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr6_-_85762480 0.773 ENSMUST00000168531.1
Cml3
camello-like 3
chr4_-_140323302 0.772 ENSMUST00000063789.2
Gm9867
predicted gene 9867
chr1_-_157256682 0.767 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr10_+_81661998 0.764 ENSMUST00000105315.2
Gm10778
predicted gene 10778
chr10_-_127620922 0.763 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr10_-_127620960 0.760 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chrX_-_7907835 0.742 ENSMUST00000085330.4
Gm10491
predicted gene 10491
chr3_-_113630068 0.739 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr4_+_141213948 0.739 ENSMUST00000097813.2
Rsg1
REM2 and RAB-like small GTPase 1
chr7_+_24257644 0.738 ENSMUST00000072713.6
Zfp108
zinc finger protein 108
chr9_-_22208546 0.735 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr11_-_115133981 0.728 ENSMUST00000106561.1
ENSMUST00000051264.7
ENSMUST00000106562.2
Cd300lf


CD300 antigen like family member F


chr3_-_36053512 0.720 ENSMUST00000166644.2
ENSMUST00000062056.8
Ccdc144b

coiled-coil domain containing 144B

chr13_-_67061131 0.719 ENSMUST00000167565.1
Zfp712
zinc finger protein 712
chr4_+_12140263 0.717 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chr7_+_24902912 0.714 ENSMUST00000117796.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr2_+_140152043 0.710 ENSMUST00000104994.2
Gm17374
predicted gene, 17374
chr5_-_86172747 0.709 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr13_-_74482943 0.706 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr2_+_69670100 0.705 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr4_-_32923455 0.701 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr4_-_86612009 0.692 ENSMUST00000125481.1
ENSMUST00000070607.7
Haus6

HAUS augmin-like complex, subunit 6

chr2_+_69722797 0.684 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr16_+_32271468 0.681 ENSMUST00000093183.3
Smco1
single-pass membrane protein with coiled-coil domains 1
chr16_+_93832121 0.677 ENSMUST00000044068.6
Morc3
microrchidia 3
chr15_+_36179530 0.676 ENSMUST00000171205.1
Spag1
sperm associated antigen 1
chr9_+_88839164 0.671 ENSMUST00000163255.2
Trim43c
tripartite motif-containing 43C
chr16_+_17208135 0.669 ENSMUST00000169803.1
Rimbp3
RIMS binding protein 3
chr11_+_58867230 0.668 ENSMUST00000132570.1
2810021J22Rik
RIKEN cDNA 2810021J22 gene
chr2_-_119541513 0.666 ENSMUST00000171024.1
Exd1
exonuclease 3'-5' domain containing 1
chr9_-_120068263 0.663 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr7_-_64374071 0.663 ENSMUST00000163289.1
Fan1
FANCD2/FANCI-associated nuclease 1
chr10_+_128499364 0.661 ENSMUST00000180477.1
A430046D13Rik
Riken cDNA A430046D13 gene
chr5_+_117133567 0.655 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr2_+_104886318 0.654 ENSMUST00000111114.1
Ccdc73
coiled-coil domain containing 73
chr10_+_58497918 0.643 ENSMUST00000036576.8
Ccdc138
coiled-coil domain containing 138
chr2_-_26380600 0.639 ENSMUST00000114115.2
ENSMUST00000035427.4
Snapc4

small nuclear RNA activating complex, polypeptide 4

chr16_-_38713235 0.638 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr10_+_58394381 0.632 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr18_+_64254359 0.631 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr10_+_58394361 0.630 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr5_+_66968559 0.630 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr7_+_24903011 0.629 ENSMUST00000047873.9
ENSMUST00000098683.4
Arhgef1

Rho guanine nucleotide exchange factor (GEF) 1

chr10_+_79996479 0.612 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr11_-_4160286 0.612 ENSMUST00000093381.4
ENSMUST00000101626.2
Ccdc157

coiled-coil domain containing 157

chr7_+_118597295 0.610 ENSMUST00000121715.1
ENSMUST00000098088.4
Tmc5

transmembrane channel-like gene family 5

chr6_-_143100028 0.607 ENSMUST00000111758.2
ENSMUST00000171349.1
ENSMUST00000087485.4
C2cd5


C2 calcium-dependent domain containing 5


chr18_+_51117754 0.606 ENSMUST00000116639.2
Prr16
proline rich 16
chr1_-_16093286 0.606 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr16_+_20517000 0.601 ENSMUST00000171572.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr17_-_46831413 0.594 ENSMUST00000040624.5
Gltscr1l
GLTSCR1-like
chr15_+_102407144 0.591 ENSMUST00000169619.1
Sp1
trans-acting transcription factor 1
chr6_+_58833689 0.587 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr9_-_78443204 0.586 ENSMUST00000070742.7
ENSMUST00000034898.7
Mb21d1

Mab-21 domain containing 1

chr18_-_46280820 0.583 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr10_-_62342674 0.580 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr2_+_79707780 0.579 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr1_-_74305607 0.576 ENSMUST00000130763.1
Tmbim1
transmembrane BAX inhibitor motif containing 1
chr7_+_45526330 0.573 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr18_-_22850738 0.571 ENSMUST00000092015.4
ENSMUST00000069215.6
Nol4

nucleolar protein 4

chr2_-_127584668 0.567 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chrX_-_37104523 0.559 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr19_-_38819156 0.558 ENSMUST00000025963.7
Noc3l
nucleolar complex associated 3 homolog (S. cerevisiae)
chr6_+_113392417 0.552 ENSMUST00000032414.4
ENSMUST00000038889.5
Ttll3

tubulin tyrosine ligase-like family, member 3

chr7_+_30169861 0.551 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr2_+_92382911 0.549 ENSMUST00000054316.2
ENSMUST00000111280.2
1700029I15Rik

RIKEN cDNA 1700029I15 gene

chr7_-_15627876 0.543 ENSMUST00000086122.3
ENSMUST00000174443.1
Obox3

oocyte specific homeobox 3

chr9_+_69397933 0.542 ENSMUST00000117610.1
ENSMUST00000145538.1
ENSMUST00000117246.1
Narg2


NMDA receptor-regulated gene 2


chr13_-_97747399 0.526 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_+_169928648 0.520 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr9_-_73039697 0.516 ENSMUST00000184035.1
ENSMUST00000098566.4
Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chrX_-_162888426 0.505 ENSMUST00000033723.3
Syap1
synapse associated protein 1
chr5_-_3893907 0.501 ENSMUST00000117463.1
ENSMUST00000044746.4
Mterf

mitochondrial transcription termination factor

chr19_+_44992127 0.500 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr8_+_88651341 0.500 ENSMUST00000109634.2
Nod2
nucleotide-binding oligomerization domain containing 2
chr9_-_29963112 0.496 ENSMUST00000075069.4
Ntm
neurotrimin
chr15_-_76639840 0.493 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr9_+_88581036 0.479 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr2_-_30359278 0.478 ENSMUST00000163668.2
ENSMUST00000028214.8
ENSMUST00000113621.3
Sh3glb2


SH3-domain GRB2-like endophilin B2


chr11_-_107348130 0.477 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_51261719 0.474 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr5_-_139775631 0.471 ENSMUST00000072607.4
Ints1
integrator complex subunit 1
chrX_-_61185558 0.467 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr16_+_11406618 0.461 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr7_+_110018301 0.461 ENSMUST00000084731.3
Ipo7
importin 7
chr7_-_44751050 0.459 ENSMUST00000126366.2
Zfp473
zinc finger protein 473
chr4_+_74242468 0.458 ENSMUST00000077851.3
Kdm4c
lysine (K)-specific demethylase 4C
chr4_+_133176336 0.451 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr9_-_73039644 0.449 ENSMUST00000184389.1
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr11_-_96916448 0.449 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr3_-_152340350 0.448 ENSMUST00000073089.6
ENSMUST00000068243.6
Fam73a

family with sequence similarity 73, member A

chr16_-_91618986 0.448 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr2_-_30359190 0.443 ENSMUST00000100215.4
ENSMUST00000113620.3
Sh3glb2

SH3-domain GRB2-like endophilin B2

chr10_-_81600857 0.442 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.7 2.0 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.7 2.0 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.6 3.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.6 1.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.6 3.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 2.4 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.4 1.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.3 2.4 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.3 0.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.3 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3 0.8 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.3 1.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 0.8 GO:0060854 patterning of lymph vessels(GO:0060854)
0.3 1.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 1.2 GO:0044838 cell quiescence(GO:0044838)
0.2 0.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.6 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.2 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.2 0.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 0.5 GO:0002925 regulation of dendritic cell cytokine production(GO:0002730) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) detection of peptidoglycan(GO:0032499) negative regulation of interleukin-18 production(GO:0032701)
0.2 0.7 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.2 0.6 GO:1990743 protein sialylation(GO:1990743)
0.2 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.7 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:1905223 epicardium morphogenesis(GO:1905223)
0.1 0.8 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 1.1 GO:0060613 fat pad development(GO:0060613)
0.1 0.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.5 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.6 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.1 1.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 1.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:1900365 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.1 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 1.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.0 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 1.0 GO:0097502 mannosylation(GO:0097502)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.5 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539) replicative senescence(GO:0090399)
0.0 4.1 GO:0001824 blastocyst development(GO:0001824)
0.0 0.1 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 1.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) atrial septum primum morphogenesis(GO:0003289) negative regulation of alkaline phosphatase activity(GO:0010693) negative regulation of macrophage cytokine production(GO:0010936) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) modulation by virus of host autophagy(GO:0039519) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.0 0.8 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 1.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0000802 transverse filament(GO:0000802)
0.2 0.5 GO:0035101 FACT complex(GO:0035101)
0.1 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.9 GO:0042588 zymogen granule(GO:0042588)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0033202 DNA helicase complex(GO:0033202)
0.0 2.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.7 2.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.5 3.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 1.5 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 2.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 1.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 0.8 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.3 1.6 GO:0019841 retinol binding(GO:0019841)
0.2 1.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.6 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.2 2.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 0.6 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.5 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.2 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.4 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.8 GO:0031005 filamin binding(GO:0031005)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.9 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.5 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.3 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.6 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 5.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 3.5 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.3 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 1.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism