Motif ID: Crx_Gsc

Z-value: 0.566

Transcription factors associated with Crx_Gsc:

Gene SymbolEntrez IDGene Name
Crx ENSMUSG00000041578.9 Crx
Gsc ENSMUSG00000021095.4 Gsc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Crxmm10_v2_chr7_-_15879844_158799680.361.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Crx_Gsc

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_+_1010543 2.313 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr4_+_74013442 1.624 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr11_+_104231390 1.569 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr9_-_53975246 1.460 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr2_+_69722797 1.094 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr1_-_154725920 0.981 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr7_+_44384803 0.971 ENSMUST00000120262.1
Syt3
synaptotagmin III
chr1_+_85575676 0.943 ENSMUST00000178024.1
G530012D18Rik
RIKEN cDNA G530012D1 gene
chr14_+_61138445 0.938 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr8_-_54724317 0.914 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr7_+_44384098 0.909 ENSMUST00000118962.1
ENSMUST00000118831.1
Syt3

synaptotagmin III

chr14_+_65968483 0.892 ENSMUST00000022616.6
Clu
clusterin
chr12_-_69357120 0.823 ENSMUST00000021368.8
Nemf
nuclear export mediator factor
chr13_+_110395041 0.812 ENSMUST00000022212.7
Plk2
polo-like kinase 2
chr11_-_70459957 0.759 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr7_+_44384604 0.683 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III

chr2_-_164404606 0.670 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4


matrilin 4


chr8_-_54724474 0.668 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr7_+_99535439 0.651 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr12_-_25096080 0.637 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr17_+_37002527 0.636 ENSMUST00000174747.1
Zfp57
zinc finger protein 57
chr2_-_104257400 0.619 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr6_-_59426279 0.615 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr10_+_90576872 0.599 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr4_+_84884418 0.588 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr10_-_53379816 0.570 ENSMUST00000095691.5
Cep85l
centrosomal protein 85-like
chr5_+_129584169 0.563 ENSMUST00000031390.8
Mmp17
matrix metallopeptidase 17
chrX_+_7919816 0.560 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_24763047 0.555 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr10_+_83543941 0.552 ENSMUST00000038388.5
A230046K03Rik
RIKEN cDNA A230046K03 gene
chr15_-_84065329 0.552 ENSMUST00000156187.1
Efcab6
EF-hand calcium binding domain 6
chr11_+_101246405 0.549 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr19_+_26605106 0.542 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr17_+_55445550 0.539 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr12_+_81631369 0.534 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr14_-_19977249 0.533 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr4_+_84884276 0.519 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chrX_-_85776606 0.518 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
Gyk


glycerol kinase


chr15_+_82252397 0.515 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr8_-_45975224 0.513 ENSMUST00000095323.1
ENSMUST00000098786.2
1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr2_+_181680284 0.498 ENSMUST00000103042.3
Tcea2
transcription elongation factor A (SII), 2
chr17_+_37002510 0.492 ENSMUST00000069250.7
Zfp57
zinc finger protein 57
chr1_-_189688074 0.484 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr6_+_41605482 0.482 ENSMUST00000114732.2
Ephb6
Eph receptor B6
chr11_+_70459940 0.481 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr7_+_99535652 0.472 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr18_+_37477768 0.457 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr13_-_27582168 0.438 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr11_+_49203465 0.437 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr4_+_134496996 0.432 ENSMUST00000095074.3
Paqr7
progestin and adipoQ receptor family member VII
chr4_-_138396438 0.426 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr9_+_13827708 0.418 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr2_+_65845767 0.417 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr6_+_58831748 0.414 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chrX_+_73483602 0.413 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr8_+_20136455 0.411 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chr1_-_155417394 0.411 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr7_-_140082246 0.408 ENSMUST00000166758.2
Caly
calcyon neuron-specific vesicular protein
chr14_-_19977151 0.404 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr14_-_19977040 0.401 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr9_+_95954744 0.389 ENSMUST00000034981.7
Xrn1
5'-3' exoribonuclease 1
chr1_-_119837613 0.381 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr11_-_116412965 0.377 ENSMUST00000100202.3
ENSMUST00000106398.2
Rnf157

ring finger protein 157

chr4_-_141078302 0.374 ENSMUST00000030760.8
Necap2
NECAP endocytosis associated 2
chr1_-_155417283 0.372 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr5_+_117120120 0.371 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr11_+_101246960 0.370 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr10_-_9901079 0.367 ENSMUST00000141722.1
Stxbp5
syntaxin binding protein 5 (tomosyn)
chr9_-_95750335 0.358 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr1_-_150392719 0.357 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr6_+_86404336 0.351 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr8_+_119344490 0.347 ENSMUST00000034300.6
Hsbp1
heat shock factor binding protein 1
chr2_+_65845833 0.345 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_-_127341583 0.339 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr4_+_141368116 0.335 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr1_+_150392794 0.331 ENSMUST00000124973.2
Tpr
translocated promoter region
chr18_+_42511496 0.330 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr5_-_139484420 0.327 ENSMUST00000150992.1
Zfand2a
zinc finger, AN1-type domain 2A
chr17_+_35517100 0.323 ENSMUST00000164242.2
ENSMUST00000045956.7
Cchcr1

coiled-coil alpha-helical rod protein 1

chr9_+_87144285 0.323 ENSMUST00000113149.1
ENSMUST00000143779.1
ENSMUST00000179313.1
ENSMUST00000049457.7
ENSMUST00000153444.1
Mrap2




melanocortin 2 receptor accessory protein 2




chr6_+_86404219 0.319 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chr6_+_86404257 0.308 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr19_+_3767397 0.306 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chr18_+_37489465 0.302 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr4_+_12906838 0.301 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr13_+_119462752 0.300 ENSMUST00000026519.8
4833420G17Rik
RIKEN cDNA 4833420G17 gene
chr11_-_69837781 0.296 ENSMUST00000108634.2
Nlgn2
neuroligin 2
chr12_+_55124528 0.295 ENSMUST00000177768.1
Fam177a
family with sequence similarity 177, member A
chr2_+_19344820 0.294 ENSMUST00000150514.1
ENSMUST00000136456.1
4930447M23Rik

RIKEN cDNA 4930447M23 gene

chr14_-_105177263 0.292 ENSMUST00000163499.1
Rbm26
RNA binding motif protein 26
chr17_-_10320229 0.288 ENSMUST00000053066.6
Qk
quaking
chr10_-_56228636 0.286 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr5_+_13399309 0.272 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr1_-_44218952 0.271 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr4_+_84884366 0.260 ENSMUST00000102819.3
Cntln
centlein, centrosomal protein
chr5_-_92278155 0.259 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr11_-_29247208 0.258 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr10_-_62379852 0.247 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr14_-_105177280 0.243 ENSMUST00000100327.3
ENSMUST00000022715.7
Rbm26

RNA binding motif protein 26

chr1_+_137966529 0.241 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr9_+_88581036 0.234 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr2_+_69861562 0.226 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr7_-_134938264 0.225 ENSMUST00000171394.1
Fam196a
family with sequence similarity 196, member A
chr9_+_108991902 0.224 ENSMUST00000147989.1
ENSMUST00000051873.8
Pfkfb4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

chr5_-_34513892 0.218 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chrX_-_75578188 0.216 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr10_-_62327757 0.215 ENSMUST00000139228.1
Hk1
hexokinase 1
chr9_+_109051090 0.213 ENSMUST00000059097.8
Shisa5
shisa homolog 5 (Xenopus laevis)
chr1_+_74153981 0.212 ENSMUST00000027372.7
ENSMUST00000106899.2
Cxcr2

chemokine (C-X-C motif) receptor 2

chr14_+_64588112 0.212 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr7_+_7171330 0.211 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr17_-_25570678 0.207 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr10_+_82378593 0.205 ENSMUST00000165906.1
Gm4924
predicted gene 4924
chr2_+_3770673 0.202 ENSMUST00000177037.1
Fam107b
family with sequence similarity 107, member B
chr10_+_111972664 0.202 ENSMUST00000163048.1
ENSMUST00000174653.1
Krr1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr5_-_142608785 0.197 ENSMUST00000037048.7
Mmd2
monocyte to macrophage differentiation-associated 2
chr11_+_69622024 0.193 ENSMUST00000108656.2
ENSMUST00000092969.1
Sat2

spermidine/spermine N1-acetyl transferase 2

chr9_+_45370185 0.191 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr1_-_121327672 0.191 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr5_-_139484475 0.190 ENSMUST00000110851.1
ENSMUST00000079996.6
Zfand2a

zinc finger, AN1-type domain 2A

chr13_+_49608030 0.190 ENSMUST00000021822.5
Ogn
osteoglycin
chr14_-_20546512 0.189 ENSMUST00000022355.4
ENSMUST00000161445.1
ENSMUST00000159027.1
Ppp3cb


protein phosphatase 3, catalytic subunit, beta isoform


chrX_+_74304992 0.187 ENSMUST00000015435.4
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chrX_+_38600626 0.187 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr4_-_14621494 0.184 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr9_+_37528071 0.182 ENSMUST00000002011.7
Esam
endothelial cell-specific adhesion molecule
chr9_-_13827029 0.179 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr17_-_24455265 0.178 ENSMUST00000056032.7
E4f1
E4F transcription factor 1
chr10_-_17947997 0.178 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr13_-_92354943 0.178 ENSMUST00000022220.6
Msh3
mutS homolog 3 (E. coli)
chr7_+_24399606 0.176 ENSMUST00000002280.4
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr7_-_103741322 0.174 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr11_+_67966442 0.173 ENSMUST00000021286.4
ENSMUST00000108675.1
Stx8

syntaxin 8

chrX_-_103186618 0.172 ENSMUST00000121720.1
Nap1l2
nucleosome assembly protein 1-like 2
chr11_-_100472725 0.169 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr10_+_128267997 0.167 ENSMUST00000050901.2
Apof
apolipoprotein F
chr2_+_62664279 0.165 ENSMUST00000028257.2
Gca
grancalcin
chr2_+_69861638 0.162 ENSMUST00000112260.1
Ssb
Sjogren syndrome antigen B
chr4_-_82859571 0.162 ENSMUST00000156055.1
ENSMUST00000030110.8
Zdhhc21

zinc finger, DHHC domain containing 21

chr5_+_143758293 0.154 ENSMUST00000180951.1
D130017N08Rik
RIKEN cDNA D130017N08 gene
chr14_-_77036081 0.153 ENSMUST00000142300.1
Lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr3_-_59344256 0.150 ENSMUST00000039419.6
Igsf10
immunoglobulin superfamily, member 10
chr2_+_29761528 0.150 ENSMUST00000113810.2
ENSMUST00000113809.2
ENSMUST00000113808.2
Gm13547


predicted gene 13547


chr16_-_55838827 0.147 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr17_+_25016068 0.145 ENSMUST00000137386.1
Ift140
intraflagellar transport 140
chr3_+_28781305 0.141 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr16_+_23290464 0.135 ENSMUST00000115335.1
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr10_-_59616667 0.134 ENSMUST00000020312.6
Mcu
mitochondrial calcium uniporter
chr7_-_46795661 0.131 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr2_-_32381909 0.131 ENSMUST00000048792.4
1110008P14Rik
RIKEN cDNA 1110008P14 gene
chr1_+_24678536 0.129 ENSMUST00000095062.3
Lmbrd1
LMBR1 domain containing 1
chr9_-_50617228 0.128 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
AU019823


expressed sequence AU019823


chr7_+_6474088 0.128 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr18_+_3471630 0.124 ENSMUST00000179907.1
G430049J08Rik
RIKEN cDNA G430049J08 gene
chr16_-_94526830 0.123 ENSMUST00000023615.6
Dscr3
Down syndrome critical region gene 3
chr3_-_89365233 0.122 ENSMUST00000070820.6
Dcst1
DC-STAMP domain containing 1
chr6_-_149101506 0.120 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr11_+_95010277 0.119 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr7_-_43533171 0.119 ENSMUST00000004728.5
ENSMUST00000039861.5
Cd33

CD33 antigen

chr7_+_28825202 0.118 ENSMUST00000066264.6
Ech1
enoyl coenzyme A hydratase 1, peroxisomal
chr10_-_39899238 0.115 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr1_-_43827751 0.115 ENSMUST00000128261.1
ENSMUST00000126008.1
ENSMUST00000139451.1
Uxs1


UDP-glucuronate decarboxylase 1


chr10_-_32890462 0.113 ENSMUST00000092602.1
Nkain2
Na+/K+ transporting ATPase interacting 2
chr1_-_152625212 0.112 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr19_+_5024006 0.112 ENSMUST00000025826.5
Slc29a2
solute carrier family 29 (nucleoside transporters), member 2
chr11_+_115475645 0.110 ENSMUST00000035240.6
Armc7
armadillo repeat containing 7
chr6_-_134566913 0.108 ENSMUST00000032322.8
Lrp6
low density lipoprotein receptor-related protein 6
chr10_-_4432312 0.104 ENSMUST00000126102.1
ENSMUST00000131853.1
ENSMUST00000042251.4
Rmnd1


required for meiotic nuclear division 1 homolog (S. cerevisiae)


chr13_-_90089060 0.104 ENSMUST00000161396.1
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr5_-_45450143 0.102 ENSMUST00000154962.1
Qdpr
quinoid dihydropteridine reductase
chr5_-_92435219 0.100 ENSMUST00000038514.8
Nup54
nucleoporin 54
chr10_-_78487842 0.099 ENSMUST00000069431.4
Gm9978
predicted gene 9978
chr13_+_54789377 0.099 ENSMUST00000026993.7
ENSMUST00000131692.2
ENSMUST00000163796.1
Tspan17


tetraspanin 17


chr3_+_142496924 0.096 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr4_-_56947411 0.096 ENSMUST00000107609.3
ENSMUST00000068792.6
Tmem245

transmembrane protein 245

chr11_-_48871344 0.094 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr8_-_94876269 0.091 ENSMUST00000046461.7
Dok4
docking protein 4
chr19_-_10881723 0.091 ENSMUST00000144681.1
Tmem109
transmembrane protein 109
chr16_-_63864114 0.091 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr10_+_80855275 0.089 ENSMUST00000035597.8
Sppl2b
signal peptide peptidase like 2B
chr14_-_87141206 0.089 ENSMUST00000022599.7
Diap3
diaphanous homolog 3 (Drosophila)
chr8_-_60954726 0.088 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr11_-_59809774 0.088 ENSMUST00000047706.2
ENSMUST00000102697.3
Flcn

folliculin

chr17_+_47385386 0.086 ENSMUST00000024774.7
ENSMUST00000145462.1
Guca1b

guanylate cyclase activator 1B

chr17_-_66519666 0.081 ENSMUST00000167962.1
ENSMUST00000070538.4
Rab12

RAB12, member RAS oncogene family

chr8_-_79711631 0.079 ENSMUST00000080536.6
Abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr6_+_17749170 0.079 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr1_-_163403627 0.078 ENSMUST00000045138.4
Gorab
golgin, RAB6-interacting
chr5_+_124552845 0.077 ENSMUST00000071057.7
Ddx55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr1_-_155232710 0.077 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr15_-_64382908 0.077 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr4_+_43493345 0.075 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr8_+_3393018 0.074 ENSMUST00000004684.6
ENSMUST00000145394.1
Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

chr1_-_52490736 0.073 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr19_-_8880883 0.072 ENSMUST00000096253.5
AI462493
expressed sequence AI462493
chr2_-_9878580 0.070 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr8_-_34107816 0.070 ENSMUST00000118811.1
Dctn6
dynactin 6
chr4_+_48585193 0.069 ENSMUST00000107703.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_-_104248499 0.069 ENSMUST00000050211.5
Tk2
thymidine kinase 2, mitochondrial
chr8_+_94838321 0.068 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 1.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.9 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 2.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.1 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324)
0.1 0.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 1.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.5 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.6 GO:0042756 drinking behavior(GO:0042756)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.3 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 0.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.6 GO:0033574 response to testosterone(GO:0033574)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.2 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.0 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound metabolic process(GO:0042558) pteridine-containing compound biosynthetic process(GO:0042559) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 1.0 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.6 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.5 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.2 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.0 GO:0004096 catalase activity(GO:0004096)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.4 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins