Motif ID: Tcf7l1

Z-value: 1.139


Transcription factors associated with Tcf7l1:

Gene SymbolEntrez IDGene Name
Tcf7l1 ENSMUSG00000055799.7 Tcf7l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72788952_727890610.781.3e-04Click!


Activity profile for motif Tcf7l1.

activity profile for motif Tcf7l1


Sorted Z-values histogram for motif Tcf7l1

Sorted Z-values for motif Tcf7l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf7l1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_131110350 3.958 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr14_-_98169542 3.739 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr17_-_70851189 3.493 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr9_+_85842852 3.185 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr14_+_27039001 3.097 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr11_+_108920800 2.838 ENSMUST00000140821.1
Axin2
axin2
chr15_+_34238026 2.566 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr2_+_70474923 2.566 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr18_-_62756275 2.418 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr11_+_108921648 2.379 ENSMUST00000144511.1
Axin2
axin2
chr7_-_49636847 2.137 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr3_-_57575760 2.115 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chrX_-_134161928 2.060 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr13_-_102905740 2.032 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr7_+_45216671 2.011 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr13_-_102906046 1.997 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr1_+_110099295 1.949 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr1_-_183147461 1.934 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chrX_-_48034842 1.765 ENSMUST00000039026.7
Apln
apelin
chr6_-_148944750 1.746 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr7_-_115824699 1.712 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr4_+_62583568 1.683 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr17_-_89910449 1.644 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr18_+_82914632 1.641 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr19_-_41802028 1.621 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr7_-_144939823 1.610 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr9_+_35423582 1.590 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr3_-_25212720 1.570 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr2_-_180889660 1.546 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr2_+_173022360 1.538 ENSMUST00000173997.1
Rbm38
RNA binding motif protein 38
chr2_+_173021902 1.527 ENSMUST00000029014.9
Rbm38
RNA binding motif protein 38
chr7_+_100493795 1.485 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_+_153031852 1.483 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr6_+_29735667 1.437 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr1_+_59482133 1.412 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr3_-_57575907 1.320 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr12_-_54986363 1.279 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr19_-_47919269 1.243 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr9_+_107569112 1.210 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr9_+_119402444 1.196 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr19_-_37330613 1.187 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr7_-_118129567 1.163 ENSMUST00000032888.7
Arl6ip1
ADP-ribosylation factor-like 6 interacting protein 1
chrX_+_71556874 1.125 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr17_-_35697971 1.110 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr8_+_45507768 1.094 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr2_+_174760619 1.061 ENSMUST00000029030.2
Edn3
endothelin 3
chr10_+_80150448 1.060 ENSMUST00000153477.1
Midn
midnolin
chr4_-_126468580 1.053 ENSMUST00000097888.3
Ago1
argonaute RISC catalytic subunit 1
chr7_+_73375494 1.041 ENSMUST00000094312.5
ENSMUST00000119206.1
Rgma

RGM domain family, member A

chr7_+_67655414 1.024 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr11_+_117332335 0.999 ENSMUST00000106349.1
Sept9
septin 9
chr5_+_44100442 0.991 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr7_+_127233044 0.989 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr11_+_108920342 0.973 ENSMUST00000052915.7
Axin2
axin2
chr7_+_127233227 0.972 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr4_+_107367757 0.971 ENSMUST00000139560.1
Ndc1
NDC1 transmembrane nucleoporin
chr18_-_46212595 0.944 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr1_+_88227005 0.939 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr17_+_75005523 0.921 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr8_+_79028587 0.917 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr9_+_110132015 0.916 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr10_-_13388830 0.916 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr7_-_105787544 0.914 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr2_+_152081529 0.899 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr6_-_47813512 0.892 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr14_-_52020698 0.887 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr19_-_5729618 0.853 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr2_-_26092149 0.851 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr16_-_17132377 0.833 ENSMUST00000023453.7
Sdf2l1
stromal cell-derived factor 2-like 1
chr4_+_132638987 0.822 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
Eya3




eyes absent 3 homolog (Drosophila)




chr2_+_27079371 0.814 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr5_-_148392810 0.814 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_+_11609256 0.795 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr12_-_98737405 0.790 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr12_-_21417591 0.788 ENSMUST00000135088.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr12_-_21417526 0.780 ENSMUST00000049531.9
ENSMUST00000155480.1
Ywhaq

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

chr18_-_88894203 0.773 ENSMUST00000123826.1
Socs6
suppressor of cytokine signaling 6
chr9_+_21616166 0.769 ENSMUST00000034707.8
ENSMUST00000098948.3
Smarca4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr14_+_50924968 0.765 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
Apex1


apurinic/apyrimidinic endonuclease 1


chr17_-_47924400 0.762 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr17_+_20570362 0.756 ENSMUST00000095633.3
Gm5145
predicted pseudogene 5145
chr7_-_105787567 0.751 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr9_+_102717668 0.743 ENSMUST00000035121.7
Amotl2
angiomotin-like 2
chr1_+_136467958 0.741 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr10_-_13388753 0.737 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr17_-_47924460 0.737 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr5_+_65131184 0.711 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr5_-_134946917 0.706 ENSMUST00000051401.2
Cldn4
claudin 4
chr4_+_32983008 0.703 ENSMUST00000098190.3
ENSMUST00000029946.7
Rragd

Ras-related GTP binding D

chr3_+_32708546 0.695 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr4_-_142239356 0.686 ENSMUST00000036476.3
Kazn
kazrin, periplakin interacting protein
chrX_+_169879596 0.683 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr10_+_80151154 0.675 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr17_+_28691419 0.672 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr8_+_79028317 0.672 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr6_+_83137089 0.668 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr19_-_32466575 0.668 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr12_-_21417356 0.664 ENSMUST00000103002.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr8_+_92357787 0.662 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr10_+_53596936 0.657 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr15_-_50890396 0.639 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr10_-_4387436 0.638 ENSMUST00000100077.3
Zbtb2
zinc finger and BTB domain containing 2
chr6_+_86628174 0.626 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr8_+_86745679 0.623 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr2_+_157560078 0.615 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr1_-_78968079 0.614 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr1_+_158362330 0.610 ENSMUST00000170718.1
Astn1
astrotactin 1
chr8_+_31111816 0.609 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr9_-_65021645 0.597 ENSMUST00000036615.5
Ptplad1
protein tyrosine phosphatase-like A domain containing 1
chr11_-_87074055 0.597 ENSMUST00000020804.7
Gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr18_+_24205937 0.580 ENSMUST00000164998.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr18_-_88894322 0.578 ENSMUST00000070116.5
ENSMUST00000125362.1
Socs6

suppressor of cytokine signaling 6

chr13_-_29984219 0.568 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr6_+_38918969 0.561 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr11_-_120661175 0.561 ENSMUST00000150458.1
Notum
notum pectinacetylesterase homolog (Drosophila)
chr11_+_3649759 0.550 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr11_+_88068242 0.542 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr13_-_119408985 0.536 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr10_-_4388037 0.536 ENSMUST00000100078.2
Zbtb2
zinc finger and BTB domain containing 2
chr12_-_84408991 0.529 ENSMUST00000120942.1
ENSMUST00000110272.2
Entpd5

ectonucleoside triphosphate diphosphohydrolase 5

chr19_+_55895508 0.521 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr4_+_115057683 0.512 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr12_-_16800674 0.510 ENSMUST00000162112.1
Greb1
gene regulated by estrogen in breast cancer protein
chr9_-_99876147 0.499 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr6_+_54039558 0.499 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr10_-_117063764 0.499 ENSMUST00000047672.7
Cct2
chaperonin containing Tcp1, subunit 2 (beta)
chr5_-_123012874 0.497 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr15_-_50889691 0.496 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr5_+_110135823 0.488 ENSMUST00000112519.2
ENSMUST00000014812.8
Chfr

checkpoint with forkhead and ring finger domains

chr10_-_61979073 0.486 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr17_+_12119274 0.474 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr11_-_6274830 0.469 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chr12_+_24831583 0.466 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr3_-_127837419 0.466 ENSMUST00000051737.6
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr8_-_122678072 0.462 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr7_-_83884289 0.462 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chr11_-_87108656 0.448 ENSMUST00000051395.8
Prr11
proline rich 11
chr2_+_163658370 0.442 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr18_+_4921662 0.425 ENSMUST00000143254.1
Svil
supervillin
chr17_+_46202740 0.416 ENSMUST00000087031.5
Xpo5
exportin 5
chr11_-_77725281 0.411 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr2_+_167932327 0.410 ENSMUST00000029053.7
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr8_-_34146974 0.406 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr14_+_61599493 0.402 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr2_+_35582829 0.385 ENSMUST00000135741.1
Dab2ip
disabled 2 interacting protein
chr5_-_131538687 0.382 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr1_-_153487639 0.377 ENSMUST00000042141.5
Dhx9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr5_-_114380505 0.375 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr5_-_114380459 0.371 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chr8_-_69184177 0.368 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr12_+_53248677 0.368 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr9_-_66124872 0.368 ENSMUST00000034946.8
Snx1
sorting nexin 1
chr16_+_4968936 0.367 ENSMUST00000090457.5
4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr1_-_182019927 0.354 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr2_-_165034770 0.349 ENSMUST00000122070.1
ENSMUST00000121377.1
Ncoa5

nuclear receptor coactivator 5

chr6_+_17065129 0.349 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr18_+_24205722 0.346 ENSMUST00000170243.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr1_+_181150926 0.342 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr2_+_124610573 0.328 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr6_-_122340499 0.327 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr9_-_45984816 0.325 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr14_+_70774304 0.318 ENSMUST00000022698.7
Dok2
docking protein 2
chr13_-_54687644 0.318 ENSMUST00000129881.1
Rnf44
ring finger protein 44
chr1_-_12991109 0.311 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr3_-_89998656 0.310 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr10_+_80300997 0.307 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr2_-_165034821 0.305 ENSMUST00000153905.1
ENSMUST00000040381.8
Ncoa5

nuclear receptor coactivator 5

chr2_+_18055203 0.301 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_131153175 0.296 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
Eif2d


eukaryotic translation initiation factor 2D


chr5_+_31193227 0.287 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
Snx17


sorting nexin 17


chr12_-_83597140 0.283 ENSMUST00000048319.4
Zfyve1
zinc finger, FYVE domain containing 1
chr12_+_21111778 0.283 ENSMUST00000050990.9
Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chrX_-_57392962 0.282 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome
chr3_+_53463666 0.282 ENSMUST00000058577.4
Proser1
proline and serine rich 1
chr13_-_54687696 0.277 ENSMUST00000177950.1
ENSMUST00000146931.1
Rnf44

ring finger protein 44

chr2_+_164823001 0.276 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr14_-_70766598 0.274 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7

exportin 7

chr13_-_97747373 0.253 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr17_+_7925990 0.253 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr17_-_34603675 0.251 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr2_-_69586021 0.246 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr13_-_41358990 0.242 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr1_+_158362261 0.241 ENSMUST00000046110.9
Astn1
astrotactin 1
chr7_-_27195727 0.226 ENSMUST00000163311.2
ENSMUST00000126211.1
Snrpa

small nuclear ribonucleoprotein polypeptide A

chr8_+_35587780 0.225 ENSMUST00000037666.5
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr17_-_34031644 0.220 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr12_+_31265234 0.220 ENSMUST00000169088.1
Lamb1
laminin B1
chr19_-_10604258 0.211 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr6_-_122340525 0.209 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr5_-_5266038 0.208 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr17_+_53566971 0.206 ENSMUST00000000724.8
Kat2b
K(lysine) acetyltransferase 2B
chr17_-_34031684 0.205 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr7_+_126760591 0.200 ENSMUST00000091328.2
Mapk3
mitogen-activated protein kinase 3
chr4_+_11758147 0.192 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17

cadherin 17

chr6_-_122340200 0.191 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr19_-_5894100 0.189 ENSMUST00000055911.4
Tigd3
tigger transposable element derived 3
chr10_+_43479140 0.187 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3

BEN domain containing 3

chr12_+_31265279 0.185 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr8_-_60954726 0.181 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr1_+_132008285 0.180 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
1.3 4.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.2 3.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.7 1.4 GO:0060242 contact inhibition(GO:0060242)
0.6 1.8 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.6 1.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.5 3.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 1.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.4 1.4 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 0.9 GO:1903334 positive regulation of protein folding(GO:1903334)
0.3 1.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.2 GO:0042117 monocyte activation(GO:0042117)
0.2 3.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 1.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 1.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 3.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.4 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 1.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 1.2 GO:0002036 regulation of L-glutamate transport(GO:0002036) endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 0.6 GO:0006507 GPI anchor release(GO:0006507)
0.2 0.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 2.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.2 1.9 GO:0060539 diaphragm development(GO:0060539)
0.2 0.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 1.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 0.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 1.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.8 GO:0007403 glial cell fate determination(GO:0007403)
0.1 1.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 2.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 2.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.0 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.2 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.1 2.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.7 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.7 GO:0031424 keratinization(GO:0031424)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.4 GO:2000767 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) CRD-mediated mRNA stabilization(GO:0070934) positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 1.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.8 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.8 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 1.6 GO:0009409 response to cold(GO:0009409)
0.0 1.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0042711 maternal behavior(GO:0042711)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.2 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.6 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.9 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 1.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 1.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.9 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.5 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 4.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 1.3 GO:0008623 CHRAC(GO:0008623)
0.3 0.9 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 1.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 1.8 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 0.5 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 0.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.4 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.0 GO:0031105 septin complex(GO:0031105)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.4 GO:0001772 immunological synapse(GO:0001772)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 10.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.0 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 4.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 3.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 1.7 GO:0050436 microfibril binding(GO:0050436)
0.4 1.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 6.2 GO:0070411 I-SMAD binding(GO:0070411)
0.3 1.2 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 1.4 GO:0005113 patched binding(GO:0005113)
0.3 0.8 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 3.5 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 2.1 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.2 GO:0043559 insulin binding(GO:0043559)
0.1 2.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.2 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 2.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.8 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 9.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 0.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 3.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 2.8 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.2 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.7 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_MYC_PATHWAY C-MYC pathway
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.1 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 1.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_ERBB4_PATHWAY ErbB4 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 2.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 2.9 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.3 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA