Motif ID: Nkx2-3

Z-value: 1.198


Transcription factors associated with Nkx2-3:

Gene SymbolEntrez IDGene Name
Nkx2-3 ENSMUSG00000044220.12 Nkx2-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-3mm10_v2_chr19_+_43612299_436123250.701.2e-03Click!


Activity profile for motif Nkx2-3.

activity profile for motif Nkx2-3


Sorted Z-values histogram for motif Nkx2-3

Sorted Z-values for motif Nkx2-3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_38783503 4.914 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr12_+_38783455 4.462 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr2_+_73271925 3.175 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr19_-_59170978 2.964 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr12_-_56535047 2.608 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr6_-_6882068 2.442 ENSMUST00000142635.1
ENSMUST00000052609.8
Dlx5

distal-less homeobox 5

chr2_+_22622183 2.307 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr12_+_38780284 2.166 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr7_+_144838590 2.124 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr3_-_154330543 2.086 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr15_+_92597104 2.002 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr12_-_56536895 1.899 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr12_+_38780817 1.890 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr11_-_98053415 1.666 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr19_+_43612299 1.599 ENSMUST00000057178.9
Nkx2-3
NK2 homeobox 3
chr3_-_154328634 1.359 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr13_+_42866247 1.287 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr12_+_38781093 1.284 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr2_-_36104060 1.280 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr5_-_72587544 1.224 ENSMUST00000031124.4
Gm5868
predicted gene 5868
chr1_+_187997821 1.221 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr1_+_187997835 1.182 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr8_-_48555846 1.180 ENSMUST00000110345.1
ENSMUST00000110343.1
Tenm3

teneurin transmembrane protein 3

chr3_+_55461758 1.157 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr13_+_83504032 1.139 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chrX_-_143933089 1.092 ENSMUST00000087313.3
Dcx
doublecortin
chr1_-_190170178 1.082 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr15_+_21111452 1.065 ENSMUST00000075132.6
Cdh12
cadherin 12
chr3_-_87174657 1.039 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr12_-_83487708 1.038 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr1_+_66321708 1.011 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr14_+_25607797 0.973 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr1_+_66322102 0.944 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr1_+_72284367 0.942 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr2_-_65529275 0.905 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_+_127172866 0.875 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr11_+_16257706 0.795 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr18_+_4993795 0.777 ENSMUST00000153016.1
Svil
supervillin
chr9_+_32116040 0.749 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr8_-_109251698 0.740 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr10_+_94576254 0.737 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr3_-_126998408 0.728 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr11_+_94044111 0.702 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr4_-_129261394 0.665 ENSMUST00000145261.1
C77080
expressed sequence C77080
chr11_-_37235882 0.644 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr5_+_19907774 0.635 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_190170671 0.635 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr5_-_5266038 0.633 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr1_-_93101825 0.625 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr11_-_79504078 0.621 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr19_+_38264761 0.594 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr10_+_99263224 0.593 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr11_+_120232921 0.586 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr3_+_62419668 0.584 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr3_+_84952146 0.581 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr2_-_114013619 0.573 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr5_+_144100387 0.573 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr10_+_94575257 0.571 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr9_-_96437434 0.567 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr1_-_37496095 0.564 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr9_-_44305595 0.547 ENSMUST00000034629.4
Hinfp
histone H4 transcription factor
chr18_+_4920509 0.543 ENSMUST00000126977.1
Svil
supervillin
chr14_-_48667508 0.541 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr6_+_15196949 0.539 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr12_+_52699297 0.520 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr12_+_74297474 0.519 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr15_+_92051153 0.515 ENSMUST00000169825.1
Cntn1
contactin 1
chr6_+_29853746 0.514 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr5_+_89027959 0.513 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr13_+_42680565 0.501 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr6_-_136171722 0.491 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_-_20968526 0.483 ENSMUST00000141298.2
ENSMUST00000125783.2
Arhgap21

Rho GTPase activating protein 21

chr8_-_22694061 0.481 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr18_+_88971790 0.478 ENSMUST00000023828.7
Rttn
rotatin
chr12_-_16589743 0.476 ENSMUST00000111067.2
ENSMUST00000067124.5
Lpin1

lipin 1

chr6_+_34354119 0.461 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr4_-_45408646 0.458 ENSMUST00000153904.1
ENSMUST00000132815.2
ENSMUST00000107796.1
ENSMUST00000116341.3
Slc25a51



solute carrier family 25, member 51



chr5_-_73191848 0.454 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr2_+_67748212 0.448 ENSMUST00000180887.1
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr4_+_119814495 0.447 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr15_+_25773985 0.434 ENSMUST00000125667.1
Myo10
myosin X
chrX_-_23285532 0.431 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr19_+_8802486 0.429 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr9_+_54980880 0.418 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr5_+_117781017 0.415 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr6_-_47830867 0.413 ENSMUST00000058844.5
Zfp786
zinc finger protein 786
chr12_+_58211772 0.412 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr3_+_122419772 0.410 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr7_-_37772868 0.402 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr1_-_193370225 0.389 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr3_+_118430299 0.387 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr18_+_37755718 0.383 ENSMUST00000061279.7
Pcdhga9
protocadherin gamma subfamily A, 9
chr16_+_43235856 0.376 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr6_-_23248264 0.375 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr19_+_23723279 0.371 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chrX_+_37126777 0.366 ENSMUST00000016553.4
Nkap
NFKB activating protein
chrX_-_139871637 0.366 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr6_-_99044414 0.365 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr5_-_116288944 0.364 ENSMUST00000086483.3
Ccdc60
coiled-coil domain containing 60
chr15_-_100424208 0.361 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chrX_+_73675500 0.356 ENSMUST00000171398.1
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr5_-_116288978 0.350 ENSMUST00000050178.6
Ccdc60
coiled-coil domain containing 60
chr6_-_138421379 0.349 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chrX_-_59567348 0.344 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr14_-_52237791 0.342 ENSMUST00000149975.1
Chd8
chromodomain helicase DNA binding protein 8
chr11_-_95310186 0.339 ENSMUST00000103159.3
ENSMUST00000107734.3
ENSMUST00000107733.3
Kat7


K(lysine) acetyltransferase 7


chr2_+_152847993 0.337 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chrX_-_59568068 0.337 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr3_+_134236483 0.337 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr6_-_120038647 0.336 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr2_-_166155624 0.335 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr15_+_102073773 0.328 ENSMUST00000169681.1
Eif4b
eukaryotic translation initiation factor 4B
chr1_-_162859684 0.327 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr2_-_45112890 0.324 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr1_-_193370260 0.321 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr15_-_81360739 0.320 ENSMUST00000023040.7
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chrX_-_48208870 0.319 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr8_-_8639363 0.317 ENSMUST00000152698.1
Efnb2
ephrin B2
chr2_-_32424005 0.316 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr16_-_3909192 0.307 ENSMUST00000181699.1
1700016D08Rik
RIKEN cDNA 1700016D08 gene
chr18_-_75697639 0.307 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr16_-_74411776 0.303 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chrX_+_93654863 0.298 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr9_+_106170918 0.293 ENSMUST00000020490.5
Wdr82
WD repeat domain containing 82
chr2_-_7395879 0.293 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chrX_-_48208566 0.292 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr17_+_3397189 0.289 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr19_+_11912389 0.289 ENSMUST00000061618.7
Patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr1_-_152625212 0.285 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr2_-_147186389 0.284 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr16_-_16829276 0.276 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr14_-_62454793 0.275 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr4_-_59783800 0.268 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chrX_+_150547375 0.268 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr4_+_99955715 0.264 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr3_+_159839729 0.263 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr9_+_34486125 0.263 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr10_-_20725023 0.261 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr6_+_124304646 0.259 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr12_-_11436607 0.259 ENSMUST00000072299.5
Vsnl1
visinin-like 1
chr11_-_95309557 0.258 ENSMUST00000092766.5
ENSMUST00000072621.5
Kat7

K(lysine) acetyltransferase 7

chr3_+_137624031 0.256 ENSMUST00000165845.1
Ddit4l
DNA-damage-inducible transcript 4-like
chr3_+_138065052 0.252 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr12_+_71048338 0.247 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr12_-_98259416 0.247 ENSMUST00000021390.7
Galc
galactosylceramidase
chr6_-_148946146 0.245 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chrX_-_74246534 0.244 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr1_+_179961110 0.241 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr15_-_37459327 0.240 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr5_+_150756295 0.238 ENSMUST00000110486.1
Pds5b
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_-_166155272 0.237 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr4_-_129378116 0.232 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chrX_+_99975570 0.231 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr7_-_37773555 0.231 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr19_-_46969474 0.229 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr7_+_27553244 0.228 ENSMUST00000067386.7
2310022A10Rik
RIKEN cDNA 2310022A10 gene
chr13_-_113663670 0.222 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr5_+_89028035 0.222 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr1_-_165934900 0.220 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr13_-_117025505 0.220 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chrX_-_143933204 0.219 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr8_+_45627946 0.215 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr18_+_37320374 0.214 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr10_+_69925954 0.212 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr6_+_29859686 0.210 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr12_-_87443800 0.204 ENSMUST00000162961.1
Alkbh1
alkB, alkylation repair homolog 1 (E. coli)
chr6_-_138422898 0.204 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr11_+_103133333 0.203 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr12_-_72408934 0.201 ENSMUST00000078505.7
Rtn1
reticulon 1
chr6_+_29859662 0.194 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr8_+_45628176 0.192 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr7_-_19699008 0.191 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr4_+_85205120 0.190 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr1_+_180111339 0.190 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chrX_-_74249819 0.186 ENSMUST00000114299.1
Flna
filamin, alpha
chr2_+_112284561 0.185 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr18_-_66022580 0.184 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr1_+_183388981 0.182 ENSMUST00000097043.5
Taf1a
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr4_+_102589687 0.182 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr8_+_13060908 0.180 ENSMUST00000033822.2
Proz
protein Z, vitamin K-dependent plasma glycoprotein
chr7_-_121074501 0.180 ENSMUST00000047194.2
Igsf6
immunoglobulin superfamily, member 6
chr16_+_14705832 0.175 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr11_-_116189542 0.174 ENSMUST00000148601.1
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr17_+_25188380 0.167 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chrX_-_95658416 0.164 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr2_+_3114220 0.164 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr15_-_79285502 0.157 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chrX_-_95658392 0.150 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr7_+_123123870 0.145 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr8_+_23669653 0.143 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr8_+_4238815 0.142 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr4_+_141115660 0.141 ENSMUST00000181450.1
4921514A10Rik
RIKEN cDNA 4921514A10 gene
chr9_+_106368594 0.140 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr3_+_55782500 0.140 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr13_-_75943812 0.139 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr15_-_100424092 0.137 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_-_40346290 0.137 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr19_-_14597983 0.137 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr13_+_23555023 0.136 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr6_+_63255971 0.131 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0021759 globus pallidus development(GO:0021759)
1.3 14.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.8 2.4 GO:0060166 olfactory pit development(GO:0060166)
0.6 1.7 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5 2.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.4 0.8 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.4 1.1 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.4 3.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.3 2.1 GO:0030916 otic vesicle formation(GO:0030916)
0.3 1.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 1.8 GO:0097264 self proteolysis(GO:0097264)
0.2 0.6 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.2 0.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.9 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.5 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.1 0.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.7 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 4.8 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.7 GO:0036371 T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0015867 ATP transport(GO:0015867)
0.1 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.2 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.1 3.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 2.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.3 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 1.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 1.0 GO:0007588 excretion(GO:0007588)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) testosterone biosynthetic process(GO:0061370) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.7 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.4 GO:0072337 modified amino acid transport(GO:0072337)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0061738 late endosomal microautophagy(GO:0061738) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.5 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 2.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.0 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0005818 aster(GO:0005818)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 2.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 2.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 3.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 9.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.6 GO:0017022 myosin binding(GO:0017022)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.5 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 2.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 2.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.7 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 2.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols