Motif ID: Hcfc1_Six5_Smarcc2_Zfp143

Z-value: 1.752


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Six5mm10_v2_chr7_+_19094594_190946330.409.9e-02Click!
Hcfc1mm10_v2_chrX_-_73966329_739663760.322.0e-01Click!
Zfp143mm10_v2_chr7_+_110061702_1100617320.292.5e-01Click!
Smarcc2mm10_v2_chr10_+_128459236_1284592480.097.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Hcfc1_Six5_Smarcc2_Zfp143

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_44997221 1.964 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr7_-_44997535 1.750 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr14_+_64950037 1.697 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr7_+_12897800 1.596 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
Zscan22



zinc finger and SCAN domain containing 22



chr17_+_80127447 1.451 ENSMUST00000039205.4
Galm
galactose mutarotase
chr7_+_19024387 1.391 ENSMUST00000153976.1
Sympk
symplekin
chr2_+_118598209 1.339 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr4_-_116708312 1.334 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr5_+_24423851 1.312 ENSMUST00000141966.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr14_-_64949632 1.301 ENSMUST00000176832.1
Hmbox1
homeobox containing 1
chr5_-_149636331 1.109 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1



heat shock 105kDa/110kDa protein 1



chr11_+_4704642 1.044 ENSMUST00000009220.4
Zmat5
zinc finger, matrin type 5
chr5_-_5514730 1.022 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr5_-_134314378 0.992 ENSMUST00000174867.1
Gtf2i
general transcription factor II I
chr1_+_131867224 0.992 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr7_+_13278778 0.986 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr5_-_33657889 0.966 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr14_-_64949838 0.948 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
Hmbox1





homeobox containing 1





chr5_-_5514873 0.946 ENSMUST00000060947.7
Cldn12
claudin 12
chr10_-_81407641 0.936 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr5_-_134314637 0.920 ENSMUST00000173504.1
Gtf2i
general transcription factor II I
chr7_-_45092198 0.916 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr6_+_124829540 0.904 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr5_+_24423805 0.876 ENSMUST00000153274.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr11_+_101552188 0.873 ENSMUST00000147239.1
Nbr1
neighbor of Brca1 gene 1
chr19_-_10203880 0.858 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr7_+_24270420 0.857 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr4_+_134396320 0.841 ENSMUST00000105869.2
Pafah2
platelet-activating factor acetylhydrolase 2
chr7_-_24208093 0.803 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr7_-_45092130 0.803 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr8_-_72443772 0.802 ENSMUST00000019876.5
Calr3
calreticulin 3
chr14_+_64652524 0.798 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr7_+_19024364 0.777 ENSMUST00000023882.7
Sympk
symplekin
chr5_-_134314678 0.771 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
Gtf2i







general transcription factor II I







chr12_-_87147883 0.744 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2
chr7_-_29518566 0.740 ENSMUST00000181975.1
Sipa1l3
signal-induced proliferation-associated 1 like 3
chr1_-_128102412 0.736 ENSMUST00000112538.1
ENSMUST00000086614.5
Zranb3

zinc finger, RAN-binding domain containing 3

chr9_-_103202113 0.726 ENSMUST00000035157.8
Srprb
signal recognition particle receptor, B subunit
chr12_-_100159601 0.725 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chr5_+_24394388 0.721 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr10_+_59879617 0.717 ENSMUST00000142819.1
ENSMUST00000020309.6
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr1_-_128103016 0.711 ENSMUST00000097597.2
Zranb3
zinc finger, RAN-binding domain containing 3
chr6_-_34177048 0.707 ENSMUST00000019143.8
Slc35b4
solute carrier family 35, member B4
chr11_+_69995777 0.703 ENSMUST00000018716.3
Phf23
PHD finger protein 23
chr5_+_34369909 0.701 ENSMUST00000180376.1
Fam193a
family with sequence similarity 193, member A
chr15_-_9140374 0.700 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr1_+_106171752 0.689 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr11_+_69995874 0.682 ENSMUST00000101526.2
Phf23
PHD finger protein 23
chr1_+_72583245 0.677 ENSMUST00000145868.1
ENSMUST00000133123.1
ENSMUST00000047615.8
Smarcal1


SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1


chr10_+_94036001 0.668 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr4_-_41275091 0.667 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr4_+_116708571 0.664 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr4_+_156109971 0.659 ENSMUST00000072554.6
ENSMUST00000169550.1
ENSMUST00000105576.1
9430015G10Rik


RIKEN cDNA 9430015G10 gene


chr1_-_58973421 0.656 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr11_-_60046477 0.650 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
Pemt


phosphatidylethanolamine N-methyltransferase


chr1_+_156040884 0.646 ENSMUST00000060404.4
Tor1aip2
torsin A interacting protein 2
chr9_-_48480540 0.643 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr6_-_120038647 0.635 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr2_+_152847993 0.634 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr10_-_81496329 0.634 ENSMUST00000020463.7
Ncln
nicalin homolog (zebrafish)
chrX_-_49288229 0.634 ENSMUST00000114918.2
ENSMUST00000033437.8
ENSMUST00000114912.1
ENSMUST00000114911.1
Enox2



ecto-NOX disulfide-thiol exchanger 2



chr7_-_30588717 0.633 ENSMUST00000006470.7
ENSMUST00000108154.2
Kmt2b

lysine (K)-specific methyltransferase 2B

chr2_-_84727350 0.625 ENSMUST00000028475.8
Clp1
CLP1, cleavage and polyadenylation factor I subunit
chr2_+_152847961 0.621 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr7_-_128237984 0.619 ENSMUST00000078816.3
9130023H24Rik
RIKEN cDNA 9130023H24 gene
chr4_+_116708624 0.611 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr12_+_79297345 0.609 ENSMUST00000079533.5
ENSMUST00000171210.1
Rad51b

RAD51 homolog B

chr1_+_178187721 0.601 ENSMUST00000159284.1
Desi2
desumoylating isopeptidase 2
chr1_-_20820213 0.596 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr3_+_88081997 0.592 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr11_-_100527862 0.591 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr18_-_80469664 0.588 ENSMUST00000036229.6
Ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr7_+_101663705 0.584 ENSMUST00000106998.1
Clpb
ClpB caseinolytic peptidase B
chr5_-_148928619 0.584 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1

katanin p60 subunit A-like 1

chr7_+_29983948 0.577 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr15_-_81729864 0.574 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
Rangap1


RAN GTPase activating protein 1


chr6_+_124829582 0.568 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr5_+_33658123 0.566 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr8_+_105860634 0.566 ENSMUST00000008594.7
Nutf2
nuclear transport factor 2
chr7_+_25268387 0.563 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr17_-_25985641 0.562 ENSMUST00000041641.8
Capn15
calpain 15
chrX_+_140956892 0.560 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr8_+_91313529 0.554 ENSMUST00000069718.7
Fto
fat mass and obesity associated
chr2_+_153345809 0.552 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr8_+_85492568 0.552 ENSMUST00000034136.5
Gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr4_-_126202335 0.551 ENSMUST00000142125.1
ENSMUST00000106141.2
Thrap3

thyroid hormone receptor associated protein 3

chr2_-_168767136 0.547 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr9_+_106281061 0.547 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr7_+_126861947 0.546 ENSMUST00000037248.3
Hirip3
HIRA interacting protein 3
chr3_+_79629074 0.546 ENSMUST00000029388.8
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr2_-_153241402 0.541 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr11_+_60699758 0.535 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr9_+_44134562 0.535 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr7_+_101663633 0.534 ENSMUST00000001884.7
Clpb
ClpB caseinolytic peptidase B
chr4_-_107178282 0.533 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr19_-_41802028 0.533 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr1_+_175880775 0.530 ENSMUST00000039725.6
Exo1
exonuclease 1
chr13_-_12258093 0.530 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr19_+_7494427 0.529 ENSMUST00000025668.7
Atl3
atlastin GTPase 3
chr2_-_38287174 0.527 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr18_+_34758890 0.525 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr4_+_116708687 0.517 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr1_+_74661794 0.515 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr18_-_35703108 0.509 ENSMUST00000025208.5
Dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr17_-_57247632 0.503 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr19_+_46056539 0.500 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr11_-_101551837 0.494 ENSMUST00000017290.4
Brca1
breast cancer 1
chr6_+_108065035 0.487 ENSMUST00000049246.6
Setmar
SET domain without mariner transposase fusion
chr4_+_62408770 0.486 ENSMUST00000084524.3
Prpf4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chrX_-_49288195 0.484 ENSMUST00000114914.1
Enox2
ecto-NOX disulfide-thiol exchanger 2
chr9_-_35176039 0.482 ENSMUST00000119847.1
ENSMUST00000034539.5
Dcps

decapping enzyme, scavenger

chr9_+_109875541 0.479 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr15_+_102296256 0.479 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr17_+_35121455 0.477 ENSMUST00000173380.1
ENSMUST00000173043.3
ENSMUST00000165306.2
Gpank1


G patch domain and ankyrin repeats 1


chr4_-_132422394 0.474 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr7_-_45062393 0.473 ENSMUST00000129101.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr17_-_35673517 0.472 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
Gtf2h4



general transcription factor II H, polypeptide 4



chr7_-_99858872 0.467 ENSMUST00000036274.6
Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr16_-_55934845 0.465 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr4_-_132422484 0.465 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr9_+_83548309 0.464 ENSMUST00000113215.3
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr2_+_119112793 0.464 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr10_+_59879556 0.464 ENSMUST00000147914.1
ENSMUST00000146590.1
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr11_+_60699718 0.464 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr6_+_13871517 0.463 ENSMUST00000181090.1
ENSMUST00000181225.1
1110019D14Rik

RIKEN cDNA 1110019D14 gene

chr9_+_49055574 0.463 ENSMUST00000034803.8
Zw10
zw10 kinetochore protein
chr15_-_98662858 0.462 ENSMUST00000162384.1
ENSMUST00000003450.8
Ddx23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr13_+_65278839 0.462 ENSMUST00000155732.1
Zfp369
zinc finger protein 369
chr2_-_27475600 0.461 ENSMUST00000147736.1
Brd3
bromodomain containing 3
chr1_-_44118757 0.460 ENSMUST00000027213.7
ENSMUST00000065767.2
Kdelc1

KDEL (Lys-Asp-Glu-Leu) containing 1

chr1_+_172482199 0.460 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr4_-_43562397 0.460 ENSMUST00000030187.7
Tln1
talin 1
chr6_+_71909046 0.459 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr11_-_100527896 0.454 ENSMUST00000107389.1
ENSMUST00000007131.9
Acly

ATP citrate lyase

chr10_-_81496313 0.454 ENSMUST00000118498.1
Ncln
nicalin homolog (zebrafish)
chr15_+_85859689 0.453 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr16_-_4789887 0.450 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chr15_-_34495180 0.448 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chr1_-_93343482 0.445 ENSMUST00000128253.1
Pask
PAS domain containing serine/threonine kinase
chr1_+_60098254 0.443 ENSMUST00000124986.1
Carf
calcium response factor
chr6_-_85333412 0.443 ENSMUST00000059034.6
ENSMUST00000045846.5
ENSMUST00000113788.1
Sfxn5


sideroflexin 5


chr15_-_102722150 0.441 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chrX_+_101254528 0.439 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr19_+_6335093 0.439 ENSMUST00000078137.5
Men1
multiple endocrine neoplasia 1
chr1_+_172481788 0.438 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr10_-_78591945 0.437 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr4_-_41503046 0.437 ENSMUST00000054920.4
AI464131
expressed sequence AI464131
chr12_-_31950170 0.435 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr7_+_127511976 0.432 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr7_+_97332311 0.432 ENSMUST00000054107.5
Kctd21
potassium channel tetramerisation domain containing 21
chr19_-_9899450 0.431 ENSMUST00000025562.7
Incenp
inner centromere protein
chr11_+_117849223 0.430 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr17_-_23673557 0.429 ENSMUST00000115489.1
Thoc6
THO complex 6 homolog (Drosophila)
chr11_+_61956779 0.423 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_+_32757234 0.421 ENSMUST00000009707.7
ENSMUST00000177382.1
ENSMUST00000140999.1
Tor2a


torsin family 2, member A


chr4_-_126202583 0.419 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr4_+_107367757 0.419 ENSMUST00000139560.1
Ndc1
NDC1 transmembrane nucleoporin
chr15_-_76069681 0.419 ENSMUST00000002603.5
ENSMUST00000063747.5
Scrib

scribbled homolog (Drosophila)

chrX_+_7697131 0.413 ENSMUST00000049896.6
Gpkow
G patch domain and KOW motifs
chr8_+_70042768 0.413 ENSMUST00000011450.6
Sugp1
SURP and G patch domain containing 1
chr6_-_13871459 0.412 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr10_-_128565827 0.412 ENSMUST00000131728.1
ENSMUST00000026425.6
Pa2g4

proliferation-associated 2G4

chr15_-_102722120 0.412 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr2_-_75981967 0.411 ENSMUST00000099994.3
Ttc30a1
tetratricopeptide repeat domain 30A1
chr7_+_100372224 0.409 ENSMUST00000051777.8
ENSMUST00000098259.4
C2cd3

C2 calcium-dependent domain containing 3

chr4_+_116708467 0.409 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr16_-_4789984 0.409 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr17_+_43667389 0.405 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr4_-_117182623 0.404 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr3_-_87885558 0.404 ENSMUST00000005015.8
Prcc
papillary renal cell carcinoma (translocation-associated)
chr4_-_119173849 0.400 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr7_-_30552255 0.395 ENSMUST00000108165.1
ENSMUST00000153594.1
BC053749

cDNA sequence BC053749

chr11_+_53519920 0.395 ENSMUST00000147912.1
Sept8
septin 8
chr1_+_181150926 0.393 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr8_+_61487715 0.391 ENSMUST00000034058.6
ENSMUST00000126575.1
Cbr4

carbonyl reductase 4

chr19_+_7494033 0.388 ENSMUST00000170373.1
Atl3
atlastin GTPase 3
chr16_+_58727910 0.386 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr15_-_76069760 0.386 ENSMUST00000109946.2
Scrib
scribbled homolog (Drosophila)
chr10_+_93453382 0.386 ENSMUST00000016033.7
Lta4h
leukotriene A4 hydrolase
chr5_-_31179901 0.386 ENSMUST00000101411.2
ENSMUST00000140793.1
Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr11_+_117849286 0.385 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr2_-_155074447 0.384 ENSMUST00000137242.1
ENSMUST00000054607.9
Ahcy

S-adenosylhomocysteine hydrolase

chr1_+_36307745 0.382 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr6_+_91473695 0.382 ENSMUST00000032183.4
Tmem43
transmembrane protein 43
chr11_-_71004387 0.382 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33

DEAH (Asp-Glu-Ala-His) box polypeptide 33

chr2_+_153241502 0.377 ENSMUST00000049863.5
ENSMUST00000099192.3
ENSMUST00000109794.1
Pofut1


protein O-fucosyltransferase 1


chr2_+_173021902 0.376 ENSMUST00000029014.9
Rbm38
RNA binding motif protein 38
chr9_+_107533945 0.375 ENSMUST00000010189.1
Tmem115
transmembrane protein 115
chr2_-_69206146 0.374 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr9_+_107587711 0.371 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr4_-_129640959 0.370 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chr6_-_120357342 0.369 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr16_-_43889669 0.368 ENSMUST00000023387.7
Qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr7_+_19119853 0.368 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr7_+_44997648 0.368 ENSMUST00000003284.8
ENSMUST00000107835.1
Irf3

interferon regulatory factor 3

chr10_-_41809607 0.365 ENSMUST00000019951.9
Cep57l1
centrosomal protein 57-like 1
chr5_+_134099704 0.365 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr11_+_53519871 0.365 ENSMUST00000120878.2
Sept8
septin 8
chr2_+_129100995 0.364 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chr16_+_92301266 0.364 ENSMUST00000063641.4
ENSMUST00000118064.1
Smim11

small integral membrane protein 11


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.5 1.4 GO:0036292 DNA rewinding(GO:0036292)
0.4 1.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.4 4.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.3 1.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 0.3 GO:0016078 tRNA catabolic process(GO:0016078)
0.3 1.5 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.3 0.8 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3 1.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.3 1.9 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.3 1.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.2 0.9 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.6 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.2 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 0.6 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.4 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.2 0.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 0.9 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 0.8 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.2 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.5 GO:0036090 cleavage furrow ingression(GO:0036090)
0.2 0.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.7 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0042148 strand invasion(GO:0042148)
0.1 2.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.7 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.6 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.6 GO:1905076 regulation of interleukin-17 secretion(GO:1905076)
0.1 0.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 1.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 2.2 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.1 0.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.5 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.6 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.7 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.4 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 1.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.3 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.1 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.6 GO:0001840 neural plate development(GO:0001840)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.7 GO:0016246 RNA interference(GO:0016246)
0.1 0.1 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.5 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.1 1.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.6 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.8 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.3 GO:0019236 response to pheromone(GO:0019236)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.1 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.2 GO:0072554 blood vessel lumenization(GO:0072554)
0.1 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.5 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 1.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.3 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.2 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.2 GO:1904729 regulation of intestinal lipid absorption(GO:1904729)
0.1 0.2 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.5 GO:0009642 response to light intensity(GO:0009642)
0.1 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.4 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.0 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 2.5 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.3 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.0 0.3 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.0 0.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.3 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.6 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.8 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 0.1 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 2.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 1.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.9 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.0 GO:0035306 positive regulation of dephosphorylation(GO:0035306)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 1.0 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.0 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.1 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.0 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.2 GO:0006301 postreplication repair(GO:0006301)
0.0 0.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.0 GO:0002489 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822)
0.0 0.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0097298 regulation of nucleus size(GO:0097298)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:0070552 BRISC complex(GO:0070552)
0.2 1.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 2.2 GO:0097165 nuclear stress granule(GO:0097165)
0.2 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 0.6 GO:1990423 RZZ complex(GO:1990423)
0.2 0.7 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 0.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 1.3 GO:0005818 aster(GO:0005818)
0.1 0.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.1 1.6 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 0.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.7 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 2.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.1 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 2.4 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.6 GO:0034464 BBSome(GO:0034464)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 2.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 1.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 2.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.5 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.0 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0031105 septin complex(GO:0031105)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 1.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 1.4 GO:0048256 flap endonuclease activity(GO:0048256)
0.2 0.9 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 1.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 2.1 GO:0036310 annealing helicase activity(GO:0036310)
0.2 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.1 GO:0000150 recombinase activity(GO:0000150)
0.2 0.8 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 1.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.9 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.6 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.1 0.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.7 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.8 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.4 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.3 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.3 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.3 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 3.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 2.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.0 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 0.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.8 PID_MYC_PATHWAY C-MYC pathway
0.1 2.7 PID_ATR_PATHWAY ATR signaling pathway
0.0 2.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID_E2F_PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 1.6 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 0.1 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 1.3 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 0.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.5 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.9 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.4 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 3.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.9 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 2.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules