Motif ID: Zfp219_Zfp740

Z-value: 1.208

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp740mm10_v2_chr15_+_102203639_1022037090.663.0e-03Click!
Zfp219mm10_v2_chr14_-_52020698_52020737-0.087.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_127620922 4.928 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr10_-_127620960 4.165 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr3_+_28263563 4.104 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr7_+_127511976 3.588 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr2_+_48949495 3.508 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr12_+_102949450 3.323 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr7_+_127777095 3.194 ENSMUST00000144406.1
Setd1a
SET domain containing 1A
chr1_-_56972437 3.090 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr16_+_44173271 2.939 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr11_-_69369377 2.827 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr13_-_29984219 2.489 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr4_+_152338619 2.426 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr7_-_78578308 2.414 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr19_-_59170978 2.387 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr12_-_27342696 2.227 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr7_-_78577771 2.224 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_64121389 2.189 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr9_-_44881274 2.161 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chr4_+_152338887 2.110 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr18_-_43393346 2.105 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr6_+_4903350 2.037 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr2_-_31141802 2.010 ENSMUST00000073879.5
ENSMUST00000100208.2
ENSMUST00000100207.2
ENSMUST00000113555.1
ENSMUST00000075326.4
ENSMUST00000113552.2
ENSMUST00000136181.1
Fnbp1






formin binding protein 1






chr2_-_36105271 1.985 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chrX_+_151803642 1.929 ENSMUST00000156616.2
Huwe1
HECT, UBA and WWE domain containing 1
chr16_+_43503607 1.877 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr1_-_168431695 1.837 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chrX_-_94123087 1.814 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr2_-_120850364 1.793 ENSMUST00000131389.1
Ttbk2
tau tubulin kinase 2
chr9_+_44499126 1.773 ENSMUST00000074989.5
Bcl9l
B cell CLL/lymphoma 9-like
chr15_-_100599864 1.718 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr7_+_25282784 1.712 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr16_+_44173239 1.634 ENSMUST00000119746.1
Gm608
predicted gene 608
chr2_-_121271315 1.558 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr10_-_127341583 1.551 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr1_-_168431502 1.533 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr15_+_57694651 1.497 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr1_+_59764264 1.476 ENSMUST00000087435.5
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr4_-_45012093 1.461 ENSMUST00000131991.1
Zbtb5
zinc finger and BTB domain containing 5
chr16_-_4213404 1.394 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr8_-_11008458 1.365 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chrX_+_9199865 1.343 ENSMUST00000069763.2
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr2_-_156392829 1.324 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chrX_-_104201126 1.321 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chr4_+_127172866 1.312 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr11_+_77216180 1.311 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr5_-_25498748 1.309 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr6_+_4903298 1.300 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr11_+_69765970 1.270 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr2_-_161109017 1.264 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr12_-_118301429 1.257 ENSMUST00000026367.9
Sp4
trans-acting transcription factor 4
chr17_-_34121944 1.252 ENSMUST00000151986.1
Brd2
bromodomain containing 2
chr5_+_75152274 1.245 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr7_-_127824469 1.228 ENSMUST00000106267.3
Stx1b
syntaxin 1B
chr2_-_120850389 1.226 ENSMUST00000143051.1
ENSMUST00000057135.7
ENSMUST00000085840.4
Ttbk2


tau tubulin kinase 2


chr1_-_56969827 1.221 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr11_+_84179852 1.203 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr4_-_118179946 1.200 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr2_+_153031852 1.192 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr5_-_25498702 1.190 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr19_+_41482632 1.189 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr8_-_46294592 1.161 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr6_-_136173492 1.155 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_-_146511899 1.146 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr17_-_45686120 1.141 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr1_-_56969864 1.132 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_45113255 1.111 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr14_+_62837679 1.105 ENSMUST00000014691.8
Wdfy2
WD repeat and FYVE domain containing 2
chr2_-_116065798 1.105 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr2_-_29253001 1.099 ENSMUST00000071201.4
Ntng2
netrin G2
chr4_+_119539716 1.097 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr4_-_151861667 1.076 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr1_+_158362330 1.076 ENSMUST00000170718.1
Astn1
astrotactin 1
chr9_+_31280525 1.075 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr15_+_102406143 1.071 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr3_+_103576081 1.065 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
Syt6



synaptotagmin VI



chr11_+_98203314 1.053 ENSMUST00000003203.7
ENSMUST00000107538.1
Cdk12

cyclin-dependent kinase 12

chr7_+_30291941 1.048 ENSMUST00000144508.1
Clip3
CAP-GLY domain containing linker protein 3
chr8_+_70501116 1.048 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr5_+_19227046 1.032 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_12385769 1.032 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr11_+_69765899 1.032 ENSMUST00000108640.1
ENSMUST00000108639.1
Zbtb4

zinc finger and BTB domain containing 4

chr1_-_168432270 1.012 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr18_-_72351009 0.992 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr4_-_88033328 0.985 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_45112890 0.961 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chrX_+_13071470 0.953 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr5_+_118560719 0.951 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr18_-_72351029 0.949 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chrX_+_151803313 0.941 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr2_-_119477613 0.940 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr17_-_34122311 0.938 ENSMUST00000025193.6
Brd2
bromodomain containing 2
chr2_-_45113216 0.935 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_160994665 0.934 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr10_-_127621107 0.933 ENSMUST00000049149.8
Lrp1
low density lipoprotein receptor-related protein 1
chr4_-_118180043 0.932 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr10_+_13966268 0.932 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_28180272 0.917 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr3_+_28263205 0.911 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr1_-_56971762 0.903 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr18_+_69346143 0.894 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr12_-_31950210 0.893 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr2_-_120850598 0.890 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr18_+_35965088 0.868 ENSMUST00000175734.1
Psd2
pleckstrin and Sec7 domain containing 2
chr3_-_89245159 0.866 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr11_-_6065538 0.855 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr14_+_21500879 0.845 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr8_+_22859528 0.840 ENSMUST00000110696.1
ENSMUST00000044331.6
Kat6a

K(lysine) acetyltransferase 6A

chr18_+_34777008 0.835 ENSMUST00000043775.7
Kdm3b
KDM3B lysine (K)-specific demethylase 3B
chr7_-_66689474 0.835 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr4_+_139380658 0.832 ENSMUST00000165860.1
ENSMUST00000097822.3
Ubr4

ubiquitin protein ligase E3 component n-recognin 4

chr3_+_88142536 0.820 ENSMUST00000107558.2
ENSMUST00000107559.2
Mef2d

myocyte enhancer factor 2D

chr7_+_28180226 0.809 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr9_+_100643755 0.809 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr19_-_28010995 0.806 ENSMUST00000172907.1
ENSMUST00000046898.9
Rfx3

regulatory factor X, 3 (influences HLA class II expression)

chr2_-_162661075 0.806 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr9_-_108190352 0.799 ENSMUST00000035208.7
Bsn
bassoon
chr11_-_69801716 0.792 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr9_-_59036387 0.785 ENSMUST00000068664.5
Neo1
neogenin
chr12_-_31950170 0.784 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chrX_+_99042581 0.783 ENSMUST00000036606.7
Stard8
START domain containing 8
chr18_+_65581704 0.773 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr4_+_144892813 0.748 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr7_-_68749170 0.748 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr9_-_44721383 0.743 ENSMUST00000148929.1
ENSMUST00000123406.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chr6_+_125009232 0.742 ENSMUST00000112428.1
Zfp384
zinc finger protein 384
chr10_+_127380799 0.737 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr5_-_134314378 0.736 ENSMUST00000174867.1
Gtf2i
general transcription factor II I
chr12_+_86678685 0.724 ENSMUST00000021681.3
Vash1
vasohibin 1
chr5_+_65764073 0.717 ENSMUST00000138239.1
ENSMUST00000087264.3
N4bp2

NEDD4 binding protein 2

chr1_-_64121456 0.716 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr16_-_38713235 0.707 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr9_+_57072024 0.705 ENSMUST00000169879.1
Sin3a
transcriptional regulator, SIN3A (yeast)
chr17_+_26941420 0.703 ENSMUST00000081285.3
ENSMUST00000177932.1
Syngap1

synaptic Ras GTPase activating protein 1 homolog (rat)

chr16_+_20673264 0.702 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr19_+_6418731 0.700 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
Nrxn2


neurexin II


chr6_+_92091378 0.696 ENSMUST00000113460.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr3_-_95217741 0.696 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr7_+_73740277 0.690 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr17_+_85620816 0.688 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr17_+_35135463 0.685 ENSMUST00000173535.1
ENSMUST00000173952.1
Bag6

BCL2-associated athanogene 6

chr7_+_44310213 0.680 ENSMUST00000107938.1
Shank1
SH3/ankyrin domain gene 1
chr5_-_134314637 0.679 ENSMUST00000173504.1
Gtf2i
general transcription factor II I
chr11_+_95712673 0.675 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr7_+_127777376 0.674 ENSMUST00000126761.1
ENSMUST00000047157.6
Setd1a

SET domain containing 1A

chr15_+_89532816 0.668 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr10_+_106470281 0.667 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr11_+_107547925 0.664 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr8_+_117257019 0.659 ENSMUST00000166750.1
Cmip
c-Maf inducing protein
chrX_-_105928547 0.659 ENSMUST00000101305.2
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr10_-_87493651 0.658 ENSMUST00000020243.7
Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr10_+_127078886 0.654 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_-_45012287 0.652 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
Zbtb5


zinc finger and BTB domain containing 5


chr2_+_156196642 0.652 ENSMUST00000037401.8
Phf20
PHD finger protein 20
chr4_-_41464816 0.651 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr15_-_53902472 0.650 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr11_+_98203059 0.646 ENSMUST00000107539.1
Cdk12
cyclin-dependent kinase 12
chr4_-_118179628 0.646 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr16_-_14159232 0.639 ENSMUST00000090300.4
Marf1
meiosis arrest female 1
chr6_+_125009261 0.639 ENSMUST00000112427.1
Zfp384
zinc finger protein 384
chr4_+_129461581 0.625 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1

BSD domain containing 1

chr5_+_64803513 0.625 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr3_+_88532314 0.623 ENSMUST00000172699.1
Mex3a
mex3 homolog A (C. elegans)
chr2_-_180225812 0.618 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr11_+_79339792 0.617 ENSMUST00000108251.2
ENSMUST00000071325.2
Nf1

neurofibromatosis 1

chr4_-_148038769 0.615 ENSMUST00000030879.5
ENSMUST00000137724.1
Clcn6

chloride channel 6

chr10_-_43174521 0.611 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr2_+_164960809 0.607 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr5_-_3803081 0.601 ENSMUST00000043551.6
Ankib1
ankyrin repeat and IBR domain containing 1
chr3_-_89245005 0.595 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr11_-_69758223 0.592 ENSMUST00000071213.3
Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr2_-_146511992 0.587 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr2_-_33371400 0.586 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr12_+_3806513 0.586 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr4_+_144893077 0.583 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr11_-_106920359 0.582 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr5_-_38684743 0.582 ENSMUST00000057258.4
ENSMUST00000178760.1
ENSMUST00000179555.1
ENSMUST00000180214.1
Zfp518b



zinc finger protein 518B



chr7_+_39588931 0.579 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr19_-_4397052 0.577 ENSMUST00000075856.4
Kdm2a
lysine (K)-specific demethylase 2A
chr13_-_101768154 0.576 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr15_+_39198244 0.572 ENSMUST00000082054.5
ENSMUST00000042917.9
Rims2

regulating synaptic membrane exocytosis 2

chr12_-_91849081 0.564 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr7_+_97579868 0.558 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr15_-_78120011 0.557 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr6_-_120038647 0.556 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr5_-_106696819 0.554 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr7_-_25132473 0.554 ENSMUST00000108418.4
ENSMUST00000108415.3
ENSMUST00000098679.3
ENSMUST00000175774.2
ENSMUST00000108417.3
ENSMUST00000108416.3
ENSMUST00000108414.1
ENSMUST00000108413.1
ENSMUST00000176408.1
Pou2f2








POU domain, class 2, transcription factor 2








chr17_+_23803179 0.552 ENSMUST00000088621.4
Srrm2
serine/arginine repetitive matrix 2
chr16_+_20517076 0.552 ENSMUST00000171774.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr2_-_73892530 0.545 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
Atf2



activating transcription factor 2



chr12_+_102948843 0.543 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chrX_-_20920911 0.542 ENSMUST00000081893.6
ENSMUST00000115345.1
Syn1

synapsin I

chr11_+_63133068 0.541 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr18_+_49832622 0.541 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr5_+_30232581 0.539 ENSMUST00000145167.1
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr11_-_69605829 0.531 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr9_-_43105718 0.529 ENSMUST00000165665.1
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chrX_-_20291728 0.527 ENSMUST00000115393.2
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr7_-_19458494 0.525 ENSMUST00000085715.5
Mark4
MAP/microtubule affinity-regulating kinase 4
chr8_+_93810832 0.522 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr4_+_119539652 0.518 ENSMUST00000044564.8
ENSMUST00000162267.1
ENSMUST00000106310.2
ENSMUST00000138845.2
Foxj3



forkhead box J3




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.5 4.6 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.2 3.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.1 4.6 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
1.0 5.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.7 2.2 GO:0060023 soft palate development(GO:0060023)
0.7 2.9 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.6 4.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 1.9 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.5 3.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 1.5 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.4 3.9 GO:0048149 behavioral response to ethanol(GO:0048149)
0.4 6.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.4 1.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.4 2.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.4 2.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 0.4 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.4 1.6 GO:0060032 notochord regression(GO:0060032)
0.4 3.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.4 1.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.4 3.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 1.4 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.3 1.7 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 0.7 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117)
0.3 1.0 GO:0097402 neuroblast migration(GO:0097402)
0.3 1.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 1.2 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.3 1.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 0.9 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.3 0.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 1.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 2.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 1.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 3.9 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.7 GO:2000331 regulation of terminal button organization(GO:2000331)
0.2 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 0.8 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.2 1.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.8 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.2 2.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 1.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 1.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.2 0.6 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.2 0.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 0.5 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752)
0.2 0.7 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.2 0.3 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.2 4.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2 0.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.5 GO:0070602 regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.2 1.1 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.1 GO:0043585 nose morphogenesis(GO:0043585)
0.1 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.3 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.8 GO:0072718 response to cisplatin(GO:0072718)
0.1 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.4 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.5 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.4 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.5 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.8 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 0.1 GO:2000830 vacuolar phosphate transport(GO:0007037) vitamin D3 metabolic process(GO:0070640) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 1.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.0 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 2.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.6 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.8 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.4 GO:0061010 gall bladder development(GO:0061010)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.3 GO:0014735 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) regulation of muscle atrophy(GO:0014735)
0.1 0.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.1 GO:1902661 regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.1 1.5 GO:0099612 protein localization to axon(GO:0099612)
0.1 2.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030)
0.1 0.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.7 GO:0046959 habituation(GO:0046959)
0.1 0.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 2.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.2 GO:0097298 regulation of nucleus size(GO:0097298)
0.1 0.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.3 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.1 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 2.1 GO:0009994 oocyte differentiation(GO:0009994)
0.1 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.7 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 2.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.3 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.2 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1904017 positive regulation of female receptivity(GO:0045925) response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.7 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.6 GO:0007143 female meiotic division(GO:0007143)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.4 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.8 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.6 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.2 GO:0007051 spindle organization(GO:0007051)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.6 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.7 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:1990859 cellular response to endothelin(GO:1990859)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.6 1.7 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.5 2.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 1.5 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 0.8 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.3 6.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 3.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 1.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 3.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 3.8 GO:0010369 chromocenter(GO:0010369)
0.2 1.9 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.7 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.2 2.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 1.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 11.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.6 GO:0097542 ciliary tip(GO:0097542)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 3.9 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.9 GO:0031011 Ino80 complex(GO:0031011)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0043511 inhibin complex(GO:0043511)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 6.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.2 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.1 2.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 6.0 GO:0055037 recycling endosome(GO:0055037)
0.1 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.6 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 1.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 5.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0000791 euchromatin(GO:0000791)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0030118 clathrin coat(GO:0030118)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 2.5 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.3 GO:0044306 neuron projection terminus(GO:0044306)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
1.1 4.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.9 4.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.8 3.9 GO:1990188 euchromatin binding(GO:1990188)
0.5 2.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 1.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.4 5.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 2.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 2.6 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.3 1.9 GO:0005042 netrin receptor activity(GO:0005042)
0.3 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 2.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 1.5 GO:0097001 ceramide binding(GO:0097001)
0.2 1.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 2.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.5 GO:0098821 BMP receptor activity(GO:0098821)
0.2 3.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 1.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.1 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 1.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.7 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 3.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 2.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.9 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 2.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.2 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.1 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.5 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 1.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0032451 demethylase activity(GO:0032451) histone demethylase activity(GO:0032452)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 5.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.7 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.5 PID_ALK2_PATHWAY ALK2 signaling events
0.1 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.3 PID_ALK1_PATHWAY ALK1 signaling events
0.1 0.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 2.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 0.9 ST_STAT3_PATHWAY STAT3 Pathway
0.1 4.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 2.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 3.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 3.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 3.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 2.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 2.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.8 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.2 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.0 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 2.0 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 2.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.8 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 0.9 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 0.9 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 2.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.9 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants