Motif ID: Brca1

Z-value: 0.505


Transcription factors associated with Brca1:

Gene SymbolEntrez IDGene Name
Brca1 ENSMUSG00000017146.6 Brca1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Brca1mm10_v2_chr11_-_101551837_1015518930.145.7e-01Click!


Activity profile for motif Brca1.

activity profile for motif Brca1


Sorted Z-values histogram for motif Brca1

Sorted Z-values for motif Brca1



Network of associatons between targets according to the STRING database.



First level regulatory network of Brca1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 1.551 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_+_44617310 0.548 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr5_-_25223153 0.452 ENSMUST00000066954.1
E130116L18Rik
RIKEN cDNA E130116L18 gene
chr18_-_47333311 0.437 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr16_-_16829276 0.425 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr7_-_144939823 0.391 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr10_-_42583628 0.376 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr17_+_71204647 0.373 ENSMUST00000126681.1
Lpin2
lipin 2
chr2_-_105399286 0.368 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr1_-_75278345 0.359 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chr13_-_49320219 0.356 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr19_-_24225015 0.352 ENSMUST00000099558.4
Tjp2
tight junction protein 2
chr11_+_59306920 0.346 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr11_-_106998483 0.341 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr1_+_192190771 0.340 ENSMUST00000078470.5
ENSMUST00000110844.1
Kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr6_-_125191535 0.314 ENSMUST00000043848.4
Ncapd2
non-SMC condensin I complex, subunit D2
chr12_+_4082596 0.280 ENSMUST00000049584.5
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr17_-_70853482 0.275 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr16_+_30065333 0.275 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr18_+_7869707 0.272 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chr3_-_138131356 0.268 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr4_-_116708312 0.267 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr3_-_61365951 0.264 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chr4_-_131838231 0.250 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr11_+_6291660 0.249 ENSMUST00000101554.2
ENSMUST00000093350.3
Ogdh

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

chr15_-_97020322 0.230 ENSMUST00000166223.1
Slc38a4
solute carrier family 38, member 4
chr3_+_87930256 0.229 ENSMUST00000055984.6
Isg20l2
interferon stimulated exonuclease gene 20-like 2
chr3_+_96172327 0.227 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr3_+_87906321 0.221 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr11_-_98625661 0.217 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chrM_+_8600 0.216 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr17_+_35841668 0.215 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr2_-_155945282 0.214 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr19_-_10203880 0.202 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chrM_+_9452 0.200 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr13_-_98890974 0.196 ENSMUST00000179301.1
ENSMUST00000179271.1
Tnpo1

transportin 1

chr12_+_52097737 0.194 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr11_+_6291607 0.192 ENSMUST00000003461.8
Ogdh
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr5_-_138187177 0.191 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr6_-_122340499 0.188 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr12_-_12940600 0.184 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr1_-_46854046 0.181 ENSMUST00000027131.4
Slc39a10
solute carrier family 39 (zinc transporter), member 10
chr5_-_115158169 0.181 ENSMUST00000053271.5
ENSMUST00000112121.1
Mlec

malectin

chr17_+_6430112 0.180 ENSMUST00000179569.1
Dynlt1b
dynein light chain Tctex-type 1B
chr17_-_47611449 0.180 ENSMUST00000024783.8
Bysl
bystin-like
chr7_-_102100227 0.178 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr9_-_37657189 0.178 ENSMUST00000117654.1
Tbrg1
transforming growth factor beta regulated gene 1
chr12_-_10900296 0.173 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr7_+_129591859 0.168 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr19_+_44562841 0.167 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr8_+_84872105 0.165 ENSMUST00000136026.1
ENSMUST00000170296.1
Syce2

synaptonemal complex central element protein 2

chr13_-_100775844 0.158 ENSMUST00000075550.3
Cenph
centromere protein H
chr17_-_6655939 0.156 ENSMUST00000179554.1
Dynlt1f
dynein light chain Tctex-type 1F
chr2_-_34870921 0.154 ENSMUST00000028225.5
Psmd5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr4_+_133176336 0.153 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr8_-_47990535 0.153 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr1_+_74791516 0.152 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr19_-_7295394 0.152 ENSMUST00000025921.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr19_+_46152505 0.145 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr14_-_67715585 0.145 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr17_+_35841491 0.144 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr9_+_88327592 0.144 ENSMUST00000034992.6
Nt5e
5' nucleotidase, ecto
chr7_+_51878967 0.143 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr8_+_25017211 0.143 ENSMUST00000033961.5
Tm2d2
TM2 domain containing 2
chr18_+_36952621 0.141 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chrX_+_71663665 0.139 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr19_-_32466575 0.133 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr8_+_26977336 0.131 ENSMUST00000154256.1
ENSMUST00000127097.1
Zfp703

zinc finger protein 703

chr3_-_100489324 0.129 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr9_-_109082372 0.128 ENSMUST00000167504.1
Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr16_-_11066141 0.126 ENSMUST00000162323.1
Litaf
LPS-induced TN factor
chr15_-_27681498 0.124 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr2_+_167932327 0.123 ENSMUST00000029053.7
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr15_-_82016134 0.120 ENSMUST00000152227.1
Desi1
desumoylating isopeptidase 1
chr6_-_108185552 0.120 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr4_+_100776664 0.120 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr2_+_174330006 0.118 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr11_+_82035569 0.117 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr10_-_33624587 0.116 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chrX_+_169685191 0.115 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr8_-_70700070 0.115 ENSMUST00000116172.1
Gm11175
predicted gene 11175
chr15_+_102460076 0.109 ENSMUST00000164688.1
Prr13
proline rich 13
chr7_+_82337218 0.106 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr11_-_30198232 0.106 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr12_+_4082574 0.106 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr12_-_108894116 0.105 ENSMUST00000109848.3
Wars
tryptophanyl-tRNA synthetase
chr10_-_77902467 0.102 ENSMUST00000057608.4
Lrrc3
leucine rich repeat containing 3
chr2_-_155582656 0.102 ENSMUST00000126322.1
Gss
glutathione synthetase
chr4_+_86053887 0.101 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
Adamtsl1



ADAMTS-like 1



chr14_-_54864055 0.100 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr10_-_13388830 0.100 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr2_+_68104671 0.099 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_-_120357342 0.094 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr7_-_113369326 0.093 ENSMUST00000047091.7
ENSMUST00000119278.1
Btbd10

BTB (POZ) domain containing 10

chr2_-_25224653 0.093 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr5_+_143651222 0.092 ENSMUST00000110727.1
Cyth3
cytohesin 3
chr12_-_69159109 0.091 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr6_-_120357440 0.089 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr19_+_6047081 0.087 ENSMUST00000025723.8
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr5_-_135064063 0.086 ENSMUST00000111205.1
ENSMUST00000141309.1
Wbscr22

Williams Beuren syndrome chromosome region 22

chr12_-_99393010 0.085 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr7_+_27553244 0.084 ENSMUST00000067386.7
2310022A10Rik
RIKEN cDNA 2310022A10 gene
chr3_-_51277470 0.084 ENSMUST00000108053.2
ENSMUST00000108051.1
Elf2

E74-like factor 2

chr2_-_9883993 0.083 ENSMUST00000114915.2
9230102O04Rik
RIKEN cDNA 9230102O04 gene
chr13_+_100651607 0.082 ENSMUST00000167256.1
Taf9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_-_102230127 0.081 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
Hdac5



histone deacetylase 5



chr19_+_36083696 0.080 ENSMUST00000025714.7
Rpp30
ribonuclease P/MRP 30 subunit
chr3_-_90433603 0.080 ENSMUST00000029542.5
ENSMUST00000071488.3
Ints3

integrator complex subunit 3

chr11_+_97415527 0.079 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr7_-_102099932 0.078 ENSMUST00000106934.1
Art5
ADP-ribosyltransferase 5
chrX_+_150589907 0.077 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_-_41464816 0.077 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr7_+_101896817 0.076 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr7_-_17027853 0.075 ENSMUST00000003183.5
Ppp5c
protein phosphatase 5, catalytic subunit
chr12_+_103388656 0.074 ENSMUST00000101094.2
ENSMUST00000021620.6
Otub2

OTU domain, ubiquitin aldehyde binding 2

chr19_+_55741810 0.072 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_-_28916668 0.071 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr13_+_24943144 0.066 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr11_-_11890368 0.065 ENSMUST00000155690.1
Ddc
dopa decarboxylase
chr16_+_22009471 0.065 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr17_-_33685386 0.064 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm


heterogeneous nuclear ribonucleoprotein M


chr1_+_66386968 0.064 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr13_-_98891036 0.064 ENSMUST00000109399.2
Tnpo1
transportin 1
chr6_-_122340525 0.064 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_-_17027807 0.061 ENSMUST00000142597.1
Ppp5c
protein phosphatase 5, catalytic subunit
chr11_-_102230091 0.061 ENSMUST00000008999.5
Hdac5
histone deacetylase 5
chr12_+_87266696 0.060 ENSMUST00000021425.6
Ahsa1
AHA1, activator of heat shock protein ATPase 1
chr17_-_15498263 0.057 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr17_-_65613521 0.057 ENSMUST00000024897.8
Vapa
vesicle-associated membrane protein, associated protein A
chr6_-_120357422 0.056 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr7_-_64872993 0.055 ENSMUST00000094331.2
Ndnl2
necdin-like 2
chr2_-_91183017 0.054 ENSMUST00000066420.5
Madd
MAP-kinase activating death domain
chr4_+_10874498 0.054 ENSMUST00000080517.7
ENSMUST00000101504.2
2610301B20Rik

RIKEN cDNA 2610301B20 gene

chr8_-_95853501 0.053 ENSMUST00000040481.3
Slc38a7
solute carrier family 38, member 7
chr13_-_95891905 0.053 ENSMUST00000068603.6
Iqgap2
IQ motif containing GTPase activating protein 2
chr14_-_61556746 0.051 ENSMUST00000100496.4
Spryd7
SPRY domain containing 7
chr5_-_21701332 0.051 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr1_+_182124737 0.050 ENSMUST00000111018.1
ENSMUST00000027792.5
Srp9

signal recognition particle 9

chr18_-_15063560 0.048 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr13_+_100651328 0.046 ENSMUST00000084721.6
ENSMUST00000022135.8
Taf9
Taf9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_+_108894272 0.046 ENSMUST00000167816.1
ENSMUST00000047115.7
Wdr25

WD repeat domain 25

chr3_-_88951146 0.045 ENSMUST00000173135.1
Dap3
death associated protein 3
chr18_+_7869342 0.042 ENSMUST00000092112.4
ENSMUST00000172018.1
ENSMUST00000168446.1
Wac


WW domain containing adaptor with coiled-coil


chr1_-_170867761 0.041 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chrX_+_150594420 0.039 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr6_+_115601907 0.039 ENSMUST00000000449.7
Mkrn2
makorin, ring finger protein, 2
chr13_+_42681513 0.038 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chrX_+_74309089 0.038 ENSMUST00000130581.1
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr11_-_109472611 0.038 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr10_-_13388753 0.036 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chrM_+_7759 0.036 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr10_-_128923948 0.036 ENSMUST00000131271.1
Bloc1s1
biogenesis of lysosome-related organelles complex-1, subunit 1
chr5_+_138187485 0.036 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr13_+_93304940 0.035 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr9_+_108392820 0.035 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr9_+_82829806 0.034 ENSMUST00000113245.2
ENSMUST00000034783.4
Irak1bp1

interleukin-1 receptor-associated kinase 1 binding protein 1

chr4_+_129058133 0.031 ENSMUST00000030584.4
ENSMUST00000168461.1
ENSMUST00000152565.1
Rnf19b


ring finger protein 19B


chr17_+_33909481 0.031 ENSMUST00000173626.1
ENSMUST00000174541.1
Daxx

Fas death domain-associated protein

chr4_-_98817537 0.030 ENSMUST00000102790.3
Kank4
KN motif and ankyrin repeat domains 4
chr8_-_107263248 0.029 ENSMUST00000080443.6
Rps18-ps3
ribosomal protein S18, pseudogene 3
chr1_+_172148015 0.029 ENSMUST00000074144.5
Dcaf8
DDB1 and CUL4 associated factor 8
chr15_+_82016369 0.028 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr8_-_86580664 0.028 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr14_+_20674311 0.026 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr7_+_5080214 0.026 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr2_-_152831665 0.024 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr5_+_147077050 0.023 ENSMUST00000050970.3
Polr1d
polymerase (RNA) I polypeptide D
chr9_+_44773027 0.021 ENSMUST00000125877.1
Ift46
intraflagellar transport 46
chr11_+_97703394 0.019 ENSMUST00000103147.4
Psmb3
proteasome (prosome, macropain) subunit, beta type 3
chr7_-_80947765 0.018 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
Sec11a


SEC11 homolog A (S. cerevisiae)


chr13_+_55714624 0.017 ENSMUST00000021959.9
Txndc15
thioredoxin domain containing 15
chr17_+_7945653 0.013 ENSMUST00000097423.2
Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr15_+_10952332 0.010 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr5_-_123666682 0.009 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr7_+_16816299 0.009 ENSMUST00000108495.2
Strn4
striatin, calmodulin binding protein 4
chr11_-_50325599 0.009 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr5_+_146833106 0.009 ENSMUST00000075453.2
ENSMUST00000099272.2
Rpl21

ribosomal protein L21

chrX_-_101222426 0.009 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr11_-_110251736 0.008 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr14_-_61556881 0.008 ENSMUST00000022497.8
Spryd7
SPRY domain containing 7
chr7_-_80947499 0.004 ENSMUST00000120285.1
Sec11a
SEC11 homolog A (S. cerevisiae)
chr11_-_101171302 0.004 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr8_-_60954726 0.003 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr18_+_36793918 0.002 ENSMUST00000001419.8
Zmat2
zinc finger, matrin type 2
chr11_-_69920581 0.001 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.4 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 0.3 GO:0021557 oculomotor nerve development(GO:0021557)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:2000427 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling