Motif ID: Hic2

Z-value: 1.799


Transcription factors associated with Hic2:

Gene SymbolEntrez IDGene Name
Hic2 ENSMUSG00000050240.8 Hic2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hic2mm10_v2_chr16_+_17233560_172336640.058.4e-01Click!


Activity profile for motif Hic2.

activity profile for motif Hic2


Sorted Z-values histogram for motif Hic2

Sorted Z-values for motif Hic2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_117781017 6.073 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr4_-_64046925 5.714 ENSMUST00000107377.3
Tnc
tenascin C
chr11_+_104231573 5.415 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr11_+_104231515 5.118 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr15_-_66831625 5.065 ENSMUST00000164163.1
Sla
src-like adaptor
chr11_+_104231465 4.959 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr1_-_56969864 4.907 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr11_+_104231390 4.760 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr10_+_127725392 4.660 ENSMUST00000026466.3
Tac2
tachykinin 2
chr6_+_103510874 4.582 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr1_-_56969827 4.454 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56978534 4.199 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_154725920 4.098 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_-_134234492 3.894 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr12_-_79007276 3.778 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr15_+_99224976 3.378 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr2_+_76406529 3.171 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
Osbpl6


oxysterol binding protein-like 6


chr1_-_134235420 3.142 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr1_+_74854954 2.963 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr15_-_43869993 2.949 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr15_+_92051153 2.860 ENSMUST00000169825.1
Cntn1
contactin 1
chr11_-_116654245 2.853 ENSMUST00000021166.5
Cygb
cytoglobin
chr15_-_83724979 2.792 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
Scube1



signal peptide, CUB domain, EGF-like 1



chr16_-_17576206 2.770 ENSMUST00000090165.4
ENSMUST00000164623.1
Slc7a4

solute carrier family 7 (cationic amino acid transporter, y+ system), member 4

chr6_-_97487801 2.769 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr7_+_49246131 2.645 ENSMUST00000064395.6
Nav2
neuron navigator 2
chr10_-_109010955 2.608 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr12_+_61523889 2.584 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr12_+_87026564 2.527 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr18_-_23038656 2.513 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr2_-_85196697 2.422 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr2_-_181156993 2.394 ENSMUST00000055990.7
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr4_+_136284658 2.373 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr6_+_141524379 2.356 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr11_+_75193783 2.305 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr10_+_58813359 2.293 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr16_+_45093611 2.277 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr7_+_91090697 2.261 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr4_+_152338887 2.242 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr7_-_46099752 2.222 ENSMUST00000180081.1
Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr1_-_136260873 2.205 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr11_+_97415527 2.194 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr7_+_91090728 2.184 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr13_+_42709482 2.171 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr11_-_81968415 2.166 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr1_-_134332928 2.157 ENSMUST00000168515.1
Ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr2_+_180499893 2.145 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr14_+_101729907 2.140 ENSMUST00000100337.3
Lmo7
LIM domain only 7
chr9_+_45430293 2.137 ENSMUST00000034592.8
Dscaml1
Down syndrome cell adhesion molecule like 1
chr18_+_35965036 2.110 ENSMUST00000176873.1
ENSMUST00000177432.1
Psd2

pleckstrin and Sec7 domain containing 2

chr2_-_163918683 2.104 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr5_+_81021583 2.092 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr2_+_70563435 2.087 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr3_+_68584154 2.048 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr13_-_14523178 2.017 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chrX_+_73503074 2.016 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr9_+_121366958 2.001 ENSMUST00000045903.6
Trak1
trafficking protein, kinesin binding 1
chr5_+_98180866 1.977 ENSMUST00000112959.1
Prdm8
PR domain containing 8
chr18_+_35965088 1.911 ENSMUST00000175734.1
Psd2
pleckstrin and Sec7 domain containing 2
chr2_+_71981184 1.910 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr4_+_152338619 1.907 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr12_-_67222549 1.906 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr5_-_71095765 1.898 ENSMUST00000000572.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr14_+_27622433 1.889 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr10_+_84576626 1.880 ENSMUST00000020223.7
Tcp11l2
t-complex 11 (mouse) like 2
chr1_+_134193432 1.838 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr2_+_118663235 1.814 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_25096080 1.778 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr10_-_83533383 1.774 ENSMUST00000146640.1
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr5_+_110544326 1.770 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr13_-_54055650 1.753 ENSMUST00000021932.5
Drd1a
dopamine receptor D1A
chr2_+_156475803 1.717 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr7_-_103813913 1.683 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr7_+_109010825 1.668 ENSMUST00000033341.5
Tub
tubby candidate gene
chr7_+_46396439 1.655 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr11_+_97450136 1.649 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr8_+_65618009 1.647 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
March1


membrane-associated ring finger (C3HC4) 1


chr3_+_156562141 1.637 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr8_+_72646679 1.636 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chrX_-_73880831 1.619 ENSMUST00000102871.3
L1cam
L1 cell adhesion molecule
chr5_+_66968961 1.618 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr4_+_136284708 1.589 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr12_+_74288735 1.588 ENSMUST00000095617.1
1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr10_+_79716588 1.587 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr11_+_16752203 1.583 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr18_+_34220890 1.574 ENSMUST00000171187.1
Apc
adenomatosis polyposis coli
chr12_-_100725028 1.550 ENSMUST00000043599.6
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr2_+_91945703 1.536 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr4_+_13743424 1.536 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_122671378 1.524 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr2_+_70562854 1.523 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr8_+_104170513 1.509 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr11_+_73018986 1.509 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr2_-_104257400 1.505 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr15_-_81697256 1.502 ENSMUST00000072910.5
Chadl
chondroadherin-like
chr4_-_129440800 1.489 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr7_+_130936172 1.486 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr18_-_78123324 1.474 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr8_+_72646728 1.467 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr9_-_57467985 1.442 ENSMUST00000046587.6
Scamp5
secretory carrier membrane protein 5
chr19_+_8664005 1.433 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr5_-_118244861 1.432 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr3_-_26133734 1.431 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr3_+_123267445 1.425 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr4_+_102570065 1.415 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_+_29373618 1.414 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr3_-_146770603 1.405 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr9_-_107710475 1.405 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_-_31126945 1.398 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr13_+_58807884 1.380 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr11_+_98836775 1.379 ENSMUST00000107479.2
Rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr3_+_68494208 1.375 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr19_+_6497772 1.365 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr7_+_113765998 1.357 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr15_-_77956658 1.351 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr3_-_84270782 1.337 ENSMUST00000054990.4
Trim2
tripartite motif-containing 2
chr4_+_43384332 1.336 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr13_+_54949388 1.329 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr13_-_54611332 1.319 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr2_+_156475844 1.314 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr2_+_68117713 1.301 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_27247260 1.299 ENSMUST00000102886.3
ENSMUST00000129975.1
Sardh

sarcosine dehydrogenase

chr3_+_55242526 1.295 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr3_-_89245829 1.294 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chr2_-_113217051 1.293 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr17_-_25433775 1.290 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr1_+_90998722 1.264 ENSMUST00000068116.6
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
chrX_+_73064787 1.256 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr9_-_79718631 1.252 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr17_-_24209377 1.239 ENSMUST00000024931.4
Ntn3
netrin 3
chr12_+_87026286 1.226 ENSMUST00000146292.1
Tmem63c
transmembrane protein 63c
chr12_+_102949450 1.224 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr18_+_34220978 1.220 ENSMUST00000079362.5
ENSMUST00000115781.3
Apc

adenomatosis polyposis coli

chr1_-_21961581 1.215 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr11_+_104132841 1.215 ENSMUST00000093925.4
Crhr1
corticotropin releasing hormone receptor 1
chr10_-_127666598 1.215 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr10_+_127165118 1.201 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr12_-_78980758 1.197 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr17_-_24205514 1.192 ENSMUST00000097376.3
ENSMUST00000168410.2
ENSMUST00000167791.2
ENSMUST00000040474.7
Tbc1d24



TBC1 domain family, member 24



chr5_+_81021202 1.190 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr10_-_43174521 1.185 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr19_+_4231899 1.177 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr12_+_16653470 1.169 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr17_+_8340399 1.167 ENSMUST00000069742.6
Prr18
proline rich region 18
chr9_-_79718518 1.167 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr7_+_122671401 1.165 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr2_-_73386396 1.143 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr1_+_75546522 1.142 ENSMUST00000138814.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr5_+_17574268 1.129 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr19_+_37550397 1.129 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr18_-_36515798 1.127 ENSMUST00000025363.5
Hbegf
heparin-binding EGF-like growth factor
chr13_+_20090500 1.125 ENSMUST00000165249.2
Elmo1
engulfment and cell motility 1
chrX_+_74329058 1.125 ENSMUST00000004326.3
Plxna3
plexin A3
chr2_-_11502090 1.122 ENSMUST00000179584.1
ENSMUST00000170196.2
ENSMUST00000171188.2
ENSMUST00000114845.3
ENSMUST00000114844.1
ENSMUST00000100411.2
Pfkfb3





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3





chr13_+_20090538 1.121 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr13_-_54611274 1.119 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr14_+_57524734 1.109 ENSMUST00000089494.4
Il17d
interleukin 17D
chr19_-_40402267 1.101 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1



chr17_-_25433263 1.095 ENSMUST00000159623.1
Cacna1h
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr7_+_110768169 1.092 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr2_+_119351222 1.086 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr9_+_45838572 1.075 ENSMUST00000078111.4
ENSMUST00000034591.4
Bace1

beta-site APP cleaving enzyme 1

chr2_-_11502067 1.071 ENSMUST00000028114.6
ENSMUST00000049849.6
Pfkfb3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

chr7_+_25306085 1.071 ENSMUST00000119703.1
ENSMUST00000108409.1
Tmem145

transmembrane protein 145

chr4_-_149307506 1.064 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr2_-_6721606 1.060 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
Celf2



CUGBP, Elav-like family member 2



chr2_+_32629467 1.059 ENSMUST00000068271.4
Ak1
adenylate kinase 1
chr4_-_42034726 1.052 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr2_+_179442427 1.043 ENSMUST00000000314.6
Cdh4
cadherin 4
chr12_-_72408934 1.041 ENSMUST00000078505.7
Rtn1
reticulon 1
chr18_-_6241470 1.041 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr11_+_62575981 1.040 ENSMUST00000102643.1
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr1_+_23761749 1.037 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr7_+_29307924 1.034 ENSMUST00000108230.1
ENSMUST00000065181.5
Dpf1

D4, zinc and double PHD fingers family 1

chr6_-_84593810 1.029 ENSMUST00000077705.3
ENSMUST00000168003.2
Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chr5_+_21186267 1.029 ENSMUST00000036031.8
Gsap
gamma-secretase activating protein
chr9_-_54560138 1.029 ENSMUST00000041901.6
Cib2
calcium and integrin binding family member 2
chr17_+_26715644 1.028 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr5_+_35057059 1.027 ENSMUST00000050709.3
Dok7
docking protein 7
chr15_-_59082026 1.027 ENSMUST00000080371.6
Mtss1
metastasis suppressor 1
chr10_-_105574435 1.025 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr2_-_166713758 1.024 ENSMUST00000036719.5
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chrX_+_93675088 1.022 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr3_+_68572245 1.022 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chrX_+_159627265 1.014 ENSMUST00000112456.2
Sh3kbp1
SH3-domain kinase binding protein 1
chrY_+_897782 1.011 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr19_+_10041548 1.007 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr18_+_34840575 1.006 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr2_-_45110241 1.001 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr18_+_34247685 0.998 ENSMUST00000066133.6
Apc
adenomatosis polyposis coli
chr1_-_190979280 0.986 ENSMUST00000166139.1
Vash2
vasohibin 2
chr3_-_146770218 0.984 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr19_-_24031006 0.983 ENSMUST00000096164.4
Fam189a2
family with sequence similarity 189, member A2
chr1_+_75375271 0.981 ENSMUST00000087122.5
Speg
SPEG complex locus
chr9_-_21918089 0.979 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
Rab3d



RAB3D, member RAS oncogene family



chr3_-_9610074 0.979 ENSMUST00000041124.7
Zfp704
zinc finger protein 704
chr7_+_44590886 0.968 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr3_+_30602056 0.963 ENSMUST00000047502.7
Mynn
myoneurin
chr5_+_30588078 0.962 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr14_+_62837679 0.961 ENSMUST00000014691.8
Wdfy2
WD repeat and FYVE domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
2.3 7.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
2.3 20.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.4 5.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.2 4.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.9 3.8 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.8 3.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.8 0.8 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.8 2.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.8 12.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.7 3.0 GO:0021586 pons maturation(GO:0021586)
0.7 2.0 GO:0050915 sensory perception of sour taste(GO:0050915)
0.6 0.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.6 1.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.6 1.8 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.6 4.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 1.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.6 1.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.6 3.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 2.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.5 1.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.5 3.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 2.5 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.5 1.5 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.5 1.5 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.5 1.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.5 1.9 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.5 0.5 GO:0060137 maternal process involved in parturition(GO:0060137)
0.5 1.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 1.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 2.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.4 1.6 GO:0070459 prolactin secretion(GO:0070459)
0.4 1.1 GO:0051542 elastin biosynthetic process(GO:0051542)
0.4 3.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 1.8 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.3 1.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.3 1.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 4.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.3 2.0 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 2.6 GO:0005513 detection of calcium ion(GO:0005513)
0.3 4.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.3 1.6 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.3 2.1 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.3 0.9 GO:0061144 alveolar secondary septum development(GO:0061144)
0.3 0.9 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 1.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 0.9 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.3 0.6 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 2.5 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.3 0.8 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.3 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 3.0 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.3 2.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 1.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 1.0 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.2 5.7 GO:0048266 behavioral response to pain(GO:0048266)
0.2 1.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 2.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 4.7 GO:0001553 luteinization(GO:0001553)
0.2 1.4 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 0.5 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 1.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.7 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 0.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 1.5 GO:0035902 response to immobilization stress(GO:0035902)
0.2 2.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 1.3 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.2 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 2.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.1 GO:0019236 response to pheromone(GO:0019236)
0.2 1.0 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 1.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 0.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 0.6 GO:0060596 mammary placode formation(GO:0060596)
0.2 1.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 0.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126) guanylate kinase-associated protein clustering(GO:0097117)
0.2 0.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 1.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 1.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.2 0.8 GO:0015744 succinate transport(GO:0015744)
0.2 0.8 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 0.8 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.2 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.7 GO:0009644 response to high light intensity(GO:0009644)
0.2 1.1 GO:0032796 uropod organization(GO:0032796)
0.2 0.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 4.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.9 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 1.1 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.2 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.7 GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.2 0.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.3 GO:0021508 ventral midline development(GO:0007418) floor plate formation(GO:0021508) floor plate development(GO:0033504) floor plate morphogenesis(GO:0033505)
0.2 0.2 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.2 0.7 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.2 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.2 2.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.2 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.2 0.9 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 1.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.5 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.2 0.5 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 2.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 3.3 GO:0033198 response to ATP(GO:0033198)
0.1 0.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.1 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.1 1.0 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 2.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 0.5 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.5 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 1.0 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 1.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 4.6 GO:0035640 exploration behavior(GO:0035640)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.4 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate specification(GO:0048866)
0.1 2.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.4 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.7 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 2.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.1 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.3 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.7 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.8 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 3.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.7 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 0.6 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.9 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.3 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.3 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 1.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.1 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.7 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.2 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.7 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 2.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.3 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452) positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.9 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.4 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 1.5 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.1 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.7 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.9 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 2.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.2 GO:0051295 establishment of meiotic spindle localization(GO:0051295) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.2 GO:1990927 negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of tumor necrosis factor secretion(GO:1904468) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:2000124 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.4 GO:0006983 ER overload response(GO:0006983)
0.1 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.1 GO:0080144 amino acid homeostasis(GO:0080144)
0.1 0.1 GO:0007494 midgut development(GO:0007494) vein smooth muscle contraction(GO:0014826)
0.1 1.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 1.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.7 GO:0007413 axonal fasciculation(GO:0007413)
0.1 1.3 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 0.7 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.1 0.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.6 GO:0048278 vesicle docking(GO:0048278)
0.1 0.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 1.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.7 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.2 GO:0019732 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.7 GO:0097502 mannosylation(GO:0097502)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.0 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.0 0.2 GO:0039535 regulation of RIG-I signaling pathway(GO:0039535)
0.0 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.9 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 1.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.6 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.5 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.7 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:2000778 positive regulation of interleukin-6 secretion(GO:2000778)
0.0 0.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.6 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.4 GO:2001197 positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.9 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.2 GO:0033034 positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0002922 positive regulation of humoral immune response(GO:0002922)
0.0 0.1 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.9 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.2 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.8 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.3 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.0 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.7 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.3 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.2 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 1.3 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 0.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.4 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.0 GO:0070099 regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100) negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.0 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.0 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.5 GO:0016236 macroautophagy(GO:0016236)
0.0 0.5 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 1.4 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.3 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:0006308 DNA catabolic process(GO:0006308)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 20.3 GO:0045298 tubulin complex(GO:0045298)
1.1 3.4 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.0 3.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.7 10.6 GO:0005614 interstitial matrix(GO:0005614)
0.6 1.9 GO:0005927 muscle tendon junction(GO:0005927)
0.6 2.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 6.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.5 2.1 GO:0032280 symmetric synapse(GO:0032280)
0.5 1.6 GO:0098855 HCN channel complex(GO:0098855)
0.4 8.5 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 2.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 1.6 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.4 1.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 0.4 GO:0097542 ciliary tip(GO:0097542)
0.4 1.9 GO:0044316 cone cell pedicle(GO:0044316)
0.4 3.8 GO:0070852 cell body fiber(GO:0070852)
0.3 1.3 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.9 GO:0005859 muscle myosin complex(GO:0005859)
0.3 0.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 0.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.3 5.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 1.0 GO:0097450 astrocyte end-foot(GO:0097450)
0.2 0.7 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2 2.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 9.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 9.9 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.2 5.5 GO:0030673 axolemma(GO:0030673)
0.2 0.4 GO:0008091 spectrin(GO:0008091)
0.2 1.4 GO:0005638 lamin filament(GO:0005638)
0.2 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 2.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.2 2.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 3.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.2 4.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 15.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 2.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.8 GO:0000145 exocyst(GO:0000145)
0.1 2.3 GO:0005771 multivesicular body(GO:0005771)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.8 GO:0033263 CORVET complex(GO:0033263)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0005901 caveola(GO:0005901)
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 2.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.8 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.0 GO:0042588 zymogen granule(GO:0042588)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 4.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 3.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.3 GO:0031201 SNARE complex(GO:0031201)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.4 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.3 GO:0038201 TOR complex(GO:0038201)
0.1 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.5 GO:0043194 axon initial segment(GO:0043194)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 4.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.0 GO:0044309 neuron spine(GO:0044309)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 1.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 21.3 GO:0099609 microtubule lateral binding(GO:0099609)
2.0 6.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.0 4.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.0 7.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
1.0 5.7 GO:0045545 syndecan binding(GO:0045545)
0.7 2.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 2.9 GO:0004096 catalase activity(GO:0004096)
0.7 2.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.6 1.8 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.6 1.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.6 2.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 2.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.6 3.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 1.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 3.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.5 1.5 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.4 1.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.4 1.7 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.4 1.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 5.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 3.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 2.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 1.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 1.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 2.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 0.9 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 1.5 GO:0015265 urea channel activity(GO:0015265)
0.3 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 0.8 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.3 1.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.6 GO:0033691 sialic acid binding(GO:0033691)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 3.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.3 2.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 0.7 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.2 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 0.7 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.2 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 3.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 2.3 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.5 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.2 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 2.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 2.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 5.9 GO:0022839 ion gated channel activity(GO:0022839)
0.2 0.5 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 4.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.1 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 3.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 2.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 5.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 4.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 4.1 GO:0030552 cAMP binding(GO:0030552)
0.1 0.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.3 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 2.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0097001 ceramide binding(GO:0097001)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 2.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.4 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.4 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.2 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 1.6 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.2 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.1 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 3.1 GO:0017022 myosin binding(GO:0017022)
0.1 1.6 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 3.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.2 GO:0042805 actinin binding(GO:0042805)
0.1 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 2.6 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.6 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0051787 filamin binding(GO:0031005) misfolded protein binding(GO:0051787)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0019104 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) DNA N-glycosylase activity(GO:0019104)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 2.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 20.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 3.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.2 7.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 3.8 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.4 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 2.8 PID_ARF_3PATHWAY Arf1 pathway
0.1 1.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 1.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 3.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 2.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 0.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.8 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.7 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.8 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.6 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 2.0 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 2.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.4 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 0.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.0 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.4 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 20.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 7.7 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 2.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 3.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 0.5 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.2 6.2 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 8.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 3.8 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 2.0 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 4.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.4 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 2.8 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 2.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.9 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.9 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.4 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.6 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 2.2 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.4 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 1.2 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.1 0.8 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.7 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 0.8 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.0 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.1 1.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.9 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 3.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.7 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 4.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.5 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.1 1.9 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.8 REACTOME_BOTULINUM_NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.9 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 0.9 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.9 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.1 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.5 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis