Motif ID: Cenpb

Z-value: 1.481


Transcription factors associated with Cenpb:

Gene SymbolEntrez IDGene Name
Cenpb ENSMUSG00000068267.4 Cenpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cenpbmm10_v2_chr2_-_131179985_131180092-0.371.3e-01Click!


Activity profile for motif Cenpb.

activity profile for motif Cenpb


Sorted Z-values histogram for motif Cenpb

Sorted Z-values for motif Cenpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cenpb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_98662227 20.054 ENSMUST00000099684.3
Gm10801
predicted gene 10801
chr2_+_172550991 6.886 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr8_-_87959560 6.172 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr13_+_48261427 4.525 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr1_-_138848576 4.405 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr7_-_137314394 4.268 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr9_-_8004585 3.527 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr5_-_99037342 2.989 ENSMUST00000161490.1
Prkg2
protein kinase, cGMP-dependent, type II
chr16_-_17125106 2.883 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr8_-_25201349 2.841 ENSMUST00000084512.4
ENSMUST00000084030.4
Tacc1

transforming, acidic coiled-coil containing protein 1

chr12_-_45074112 2.814 ENSMUST00000120531.1
ENSMUST00000143376.1
Stxbp6

syntaxin binding protein 6 (amisyn)

chr11_+_101316917 2.741 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr6_+_66535418 2.712 ENSMUST00000101343.1
Mad2l1
MAD2 mitotic arrest deficient-like 1
chr14_+_65805832 2.692 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr6_-_94700137 2.508 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr10_+_25359798 2.336 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr14_-_15438974 2.304 ENSMUST00000055211.4
Lrrc3b
leucine rich repeat containing 3B
chr17_+_87282880 2.282 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr2_+_168081004 2.192 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr12_+_59013379 2.156 ENSMUST00000021379.7
Gemin2
gem (nuclear organelle) associated protein 2
chr12_+_113156403 2.138 ENSMUST00000049271.8
4930427A07Rik
RIKEN cDNA 4930427A07 gene
chr8_+_31187317 2.120 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr6_+_85187438 2.105 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr16_-_18811972 2.098 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr1_+_87264345 2.093 ENSMUST00000118687.1
ENSMUST00000027472.6
Efhd1

EF hand domain containing 1

chr15_+_72913357 2.045 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chrX_-_48034842 2.026 ENSMUST00000039026.7
Apln
apelin
chr14_+_65806066 2.025 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr11_-_4746778 2.000 ENSMUST00000009219.2
Cabp7
calcium binding protein 7
chr13_-_23698454 1.989 ENSMUST00000102967.1
Hist1h4c
histone cluster 1, H4c
chr3_+_19188288 1.949 ENSMUST00000132035.1
Mtfr1
mitochondrial fission regulator 1
chr1_+_184034381 1.927 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr6_+_4755327 1.893 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr6_+_117907795 1.874 ENSMUST00000167657.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr10_+_67979709 1.853 ENSMUST00000117086.1
Rtkn2
rhotekin 2
chr12_-_45074457 1.738 ENSMUST00000053768.6
Stxbp6
syntaxin binding protein 6 (amisyn)
chr2_+_157279065 1.716 ENSMUST00000029171.5
Rpn2
ribophorin II
chr2_-_122369130 1.685 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr2_+_157279026 1.682 ENSMUST00000116380.2
Rpn2
ribophorin II
chr2_+_119112793 1.682 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr9_+_44379490 1.664 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr9_+_44379536 1.602 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr9_+_48495345 1.587 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr2_+_28468056 1.585 ENSMUST00000038600.3
Mrps2
mitochondrial ribosomal protein S2
chr10_+_67979592 1.579 ENSMUST00000105437.1
Rtkn2
rhotekin 2
chr9_-_36726374 1.542 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr7_-_118855984 1.530 ENSMUST00000116280.2
ENSMUST00000106550.3
ENSMUST00000063607.5
Knop1


lysine rich nucleolar protein 1


chr1_-_184033998 1.504 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr5_-_135394499 1.490 ENSMUST00000065638.4
ENSMUST00000111171.2
Pom121

nuclear pore membrane protein 121

chr17_+_23679363 1.483 ENSMUST00000024699.2
Cldn6
claudin 6
chr10_+_67979569 1.471 ENSMUST00000118160.1
Rtkn2
rhotekin 2
chr5_+_47984571 1.433 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr16_-_18876522 1.391 ENSMUST00000119273.1
Mrpl40
mitochondrial ribosomal protein L40
chr16_-_10543028 1.347 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr5_+_47984793 1.347 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2



slit homolog 2 (Drosophila)



chr16_+_36071624 1.344 ENSMUST00000164916.1
ENSMUST00000163352.1
Ccdc58

coiled-coil domain containing 58

chr5_-_138170992 1.314 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_-_35516780 1.310 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr2_-_30093642 1.292 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr18_-_84685615 1.291 ENSMUST00000025546.9
Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr19_-_10949238 1.280 ENSMUST00000025639.6
Ccdc86
coiled-coil domain containing 86
chr6_-_39557830 1.280 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr19_-_4928241 1.269 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr7_-_118856254 1.235 ENSMUST00000033277.7
Knop1
lysine rich nucleolar protein 1
chr3_-_63899437 1.223 ENSMUST00000159188.1
ENSMUST00000177143.1
Plch1

phospholipase C, eta 1

chr4_-_119232661 1.219 ENSMUST00000141112.1
AU022252
expressed sequence AU022252
chr17_+_31057686 1.216 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr10_-_7663245 1.210 ENSMUST00000163085.1
ENSMUST00000159917.1
Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr2_-_26503814 1.203 ENSMUST00000028288.4
Notch1
notch 1
chr10_+_118141787 1.158 ENSMUST00000163238.1
ENSMUST00000020437.5
ENSMUST00000164077.1
ENSMUST00000169817.1
Mdm1



transformed mouse 3T3 cell double minute 1



chr17_-_74294834 1.156 ENSMUST00000078459.6
Memo1
mediator of cell motility 1
chr7_-_5014645 1.137 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr5_-_138171248 1.129 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_-_143827391 1.126 ENSMUST00000087316.5
Capn6
calpain 6
chr2_-_39226343 1.109 ENSMUST00000028087.3
Ppp6c
protein phosphatase 6, catalytic subunit
chr6_-_47813512 1.100 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr3_+_135307711 1.090 ENSMUST00000051849.8
Slc9b2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr11_-_113751309 1.086 ENSMUST00000106616.1
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr1_+_180942452 1.073 ENSMUST00000027800.8
Tmem63a
transmembrane protein 63a
chr5_+_107900859 1.067 ENSMUST00000153590.1
Rpl5
ribosomal protein L5
chr16_+_10835046 1.056 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr1_+_16665189 1.050 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr5_-_52566264 1.049 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr2_-_30093607 1.038 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr8_-_124021008 1.027 ENSMUST00000093039.5
Taf5l
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr17_-_26095487 1.023 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr7_-_114117761 1.012 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr10_-_75860250 1.005 ENSMUST00000038169.6
Mif
macrophage migration inhibitory factor
chr17_+_24426676 0.990 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr2_-_9883993 0.984 ENSMUST00000114915.2
9230102O04Rik
RIKEN cDNA 9230102O04 gene
chr5_-_4104654 0.977 ENSMUST00000001507.4
Cyp51
cytochrome P450, family 51
chr2_-_119787504 0.970 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
Rpap1


RNA polymerase II associated protein 1


chr8_+_12395287 0.965 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr16_+_58408443 0.961 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr8_+_83997613 0.958 ENSMUST00000095228.3
Samd1
sterile alpha motif domain containing 1
chr14_-_57133585 0.954 ENSMUST00000039380.8
Gjb6
gap junction protein, beta 6
chr8_-_122678653 0.947 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr10_+_13008442 0.943 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr7_-_118855602 0.938 ENSMUST00000106549.1
ENSMUST00000126792.1
Knop1

lysine rich nucleolar protein 1

chr5_+_147860615 0.925 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chr13_-_81710937 0.920 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr1_-_175625580 0.908 ENSMUST00000027810.7
Fh1
fumarate hydratase 1
chr11_-_87086752 0.894 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr2_-_172940299 0.893 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr12_-_81594958 0.876 ENSMUST00000002756.7
ENSMUST00000161598.1
ENSMUST00000161211.1
Med6


mediator of RNA polymerase II transcription, subunit 6 homolog (yeast)


chr7_+_29983948 0.869 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr16_-_18876655 0.865 ENSMUST00000023391.8
Mrpl40
mitochondrial ribosomal protein L40
chr19_+_17394037 0.863 ENSMUST00000025617.3
Rfk
riboflavin kinase
chr10_-_85185003 0.862 ENSMUST00000020227.9
Cry1
cryptochrome 1 (photolyase-like)
chr3_+_90072641 0.852 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr5_-_33936301 0.849 ENSMUST00000030993.6
Nelfa
negative elongation factor complex member A, Whsc2
chr3_+_69721985 0.837 ENSMUST00000029358.8
Nmd3
NMD3 homolog (S. cerevisiae)
chr11_+_88099146 0.834 ENSMUST00000018522.6
Cuedc1
CUE domain containing 1
chr7_+_29238323 0.821 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yif1b


Yip1 interacting factor homolog B (S. cerevisiae)


chr10_-_18546049 0.809 ENSMUST00000020000.5
Hebp2
heme binding protein 2
chr3_+_138443085 0.804 ENSMUST00000005964.2
Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
chr2_-_26352067 0.787 ENSMUST00000028295.8
Dnlz
DNL-type zinc finger
chr2_-_3419019 0.770 ENSMUST00000115084.1
ENSMUST00000115083.1
Meig1

meiosis expressed gene 1

chr1_-_97661668 0.770 ENSMUST00000153115.1
ENSMUST00000142234.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chr16_+_44724271 0.760 ENSMUST00000048788.7
BC027231
cDNA sequence BC027231
chr5_+_107900502 0.748 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr18_-_36744518 0.747 ENSMUST00000014438.4
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr15_+_99126513 0.746 ENSMUST00000063517.4
Spats2
spermatogenesis associated, serine-rich 2
chr9_+_120127766 0.735 ENSMUST00000035105.5
Rpsa
ribosomal protein SA
chr12_-_69724830 0.732 ENSMUST00000021370.8
L2hgdh
L-2-hydroxyglutarate dehydrogenase
chr18_+_76930017 0.727 ENSMUST00000026487.4
Ier3ip1
immediate early response 3 interacting protein 1
chr2_-_3419066 0.715 ENSMUST00000115082.3
Meig1
meiosis expressed gene 1
chr15_-_75909319 0.710 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr3_+_89773562 0.708 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr12_-_103242143 0.696 ENSMUST00000074416.3
Prima1
proline rich membrane anchor 1
chr5_-_142906702 0.691 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr8_-_70659645 0.691 ENSMUST00000070173.7
Pgpep1
pyroglutamyl-peptidase I
chr17_-_15498263 0.689 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr12_+_4817545 0.688 ENSMUST00000046207.7
0610009D07Rik
RIKEN cDNA 0610009D07 gene
chr7_+_29238434 0.687 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr17_-_34603675 0.681 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr15_-_82016134 0.672 ENSMUST00000152227.1
Desi1
desumoylating isopeptidase 1
chr7_+_4915202 0.669 ENSMUST00000116354.2
Zfp628
zinc finger protein 628
chr7_-_42578588 0.661 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr15_-_76521902 0.652 ENSMUST00000164703.1
ENSMUST00000096365.3
Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr16_+_20673264 0.651 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr10_+_50895651 0.649 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr12_+_3806513 0.646 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr17_+_80290206 0.643 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr11_+_120491840 0.637 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr11_-_120457936 0.625 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr7_+_125552260 0.621 ENSMUST00000033004.6
Il4ra
interleukin 4 receptor, alpha
chr13_+_14613242 0.620 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr12_-_108275409 0.619 ENSMUST00000136175.1
Ccdc85c
coiled-coil domain containing 85C
chr11_+_69991633 0.608 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr9_-_48495321 0.597 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr14_+_66297029 0.593 ENSMUST00000022623.6
ENSMUST00000121006.1
Trim35

tripartite motif-containing 35

chr2_-_26122769 0.589 ENSMUST00000140993.1
ENSMUST00000028300.5
Nacc2

nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

chr17_-_57031468 0.577 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr2_-_69885557 0.575 ENSMUST00000060447.6
Mettl5
methyltransferase like 5
chr19_+_47014672 0.573 ENSMUST00000037636.3
Ina
internexin neuronal intermediate filament protein, alpha
chr7_+_45434833 0.564 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr16_-_96127604 0.564 ENSMUST00000133885.1
ENSMUST00000050884.7
Hmgn1

high mobility group nucleosomal binding domain 1

chr9_+_57560934 0.560 ENSMUST00000045791.9
Scamp2
secretory carrier membrane protein 2
chr11_+_97703394 0.558 ENSMUST00000103147.4
Psmb3
proteasome (prosome, macropain) subunit, beta type 3
chr5_+_10236829 0.541 ENSMUST00000101606.3
Gm10482
predicted gene 10482
chr2_-_9890026 0.528 ENSMUST00000130615.1
Gata3
GATA binding protein 3
chr1_+_63273261 0.525 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chrX_+_52791179 0.516 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr3_-_116662643 0.513 ENSMUST00000029570.5
Hiat1
hippocampus abundant gene transcript 1
chrX_-_140543177 0.512 ENSMUST00000055738.5
Tsc22d3
TSC22 domain family, member 3
chr1_+_135818593 0.494 ENSMUST00000038760.8
Lad1
ladinin
chr5_-_144358103 0.491 ENSMUST00000055190.7
Baiap2l1
BAI1-associated protein 2-like 1
chr7_+_118855735 0.482 ENSMUST00000098087.2
ENSMUST00000106547.1
Iqck

IQ motif containing K

chr14_-_43819639 0.481 ENSMUST00000100691.3
Ear1
eosinophil-associated, ribonuclease A family, member 1
chr17_+_25240166 0.471 ENSMUST00000063574.6
Tsr3
TSR3 20S rRNA accumulation
chr4_-_149454971 0.463 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr4_+_155491353 0.462 ENSMUST00000165335.1
ENSMUST00000105616.3
ENSMUST00000030940.7
Gnb1


guanine nucleotide binding protein (G protein), beta 1


chr11_-_33147400 0.452 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr1_+_136415267 0.448 ENSMUST00000027655.6
Ddx59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr1_+_171213969 0.444 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3


nuclear receptor subfamily 1, group I, member 3


chr7_+_45434876 0.443 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr1_-_97661950 0.437 ENSMUST00000053033.7
ENSMUST00000149927.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chr7_-_30729505 0.433 ENSMUST00000006478.8
Tmem147
transmembrane protein 147
chr2_+_180456234 0.424 ENSMUST00000038259.6
Slco4a1
solute carrier organic anion transporter family, member 4a1
chr7_-_132852657 0.419 ENSMUST00000033257.8
Mettl10
methyltransferase like 10
chr13_-_14613017 0.405 ENSMUST00000015816.3
Mrpl32
mitochondrial ribosomal protein L32
chr9_+_55209190 0.401 ENSMUST00000146201.1
Fbxo22
F-box protein 22
chr11_+_80428598 0.398 ENSMUST00000173938.1
ENSMUST00000017572.7
Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr15_+_82016369 0.395 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr6_-_86733268 0.388 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr1_+_172148015 0.385 ENSMUST00000074144.5
Dcaf8
DDB1 and CUL4 associated factor 8
chr16_-_5203981 0.380 ENSMUST00000147567.1
ENSMUST00000023911.4
Nagpa

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chr17_-_36951636 0.371 ENSMUST00000040402.7
ENSMUST00000174711.1
Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr18_+_10725651 0.360 ENSMUST00000165555.1
Mib1
mindbomb homolog 1 (Drosophila)
chr4_+_133130505 0.359 ENSMUST00000084241.5
ENSMUST00000138831.1
Wasf2

WAS protein family, member 2

chr11_+_101448403 0.359 ENSMUST00000010502.6
Ifi35
interferon-induced protein 35
chr15_+_61987410 0.357 ENSMUST00000160009.1
Myc
myelocytomatosis oncogene
chr7_-_144553657 0.357 ENSMUST00000168134.3
Ppfia1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr1_+_75521521 0.338 ENSMUST00000027414.9
ENSMUST00000113553.1
Stk11ip

serine/threonine kinase 11 interacting protein

chr17_-_36951338 0.330 ENSMUST00000173540.1
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr5_-_24730635 0.329 ENSMUST00000068693.5
Wdr86
WD repeat domain 86
chr9_+_120571498 0.323 ENSMUST00000165532.1
Rpl14
ribosomal protein L14
chr2_-_3512746 0.323 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr10_-_80387642 0.319 ENSMUST00000062946.6
ENSMUST00000105350.1
Mex3d

mex3 homolog D (C. elegans)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
1.1 4.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.9 2.8 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.9 4.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.8 2.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.7 2.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.7 2.0 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.6 1.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.6 3.5 GO:0060242 contact inhibition(GO:0060242)
0.6 1.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.4 0.9 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.4 3.0 GO:2001225 cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.4 1.2 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.4 1.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.4 4.6 GO:0051601 exocyst localization(GO:0051601)
0.4 1.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.4 1.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.4 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 3.3 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.3 1.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.3 0.9 GO:0006106 fumarate metabolic process(GO:0006106)
0.3 2.7 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 0.9 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.3 0.9 GO:2000850 protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.3 2.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 0.8 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.3 1.0 GO:0002035 brain renin-angiotensin system(GO:0002035) positive regulation of arachidonic acid secretion(GO:0090238)
0.2 0.7 GO:0006407 rRNA export from nucleus(GO:0006407)
0.2 0.7 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 0.8 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.2 0.8 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.2 1.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.2 0.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 0.6 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 0.5 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.2 0.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 2.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 0.6 GO:0015744 succinate transport(GO:0015744)
0.1 2.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.7 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 0.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.5 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 2.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1 2.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.0 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.5 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 1.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 3.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 2.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.6 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.2 GO:0031038 meiotic chromosome movement towards spindle pole(GO:0016344) myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) regulation of bleb assembly(GO:1904170)
0.1 1.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 1.5 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 4.7 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 2.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.2 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.1 0.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 1.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.7 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.3 GO:0031053 primary miRNA processing(GO:0031053) G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0097494 regulation of vesicle size(GO:0097494)
0.0 0.6 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 2.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 1.1 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 1.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.3 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 2.2 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 1.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0048793 pronephros development(GO:0048793)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.9 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.4 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.8 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.4 GO:0001947 heart looping(GO:0001947)
0.0 0.1 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 1.1 GO:0042471 ear morphogenesis(GO:0042471)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.1 GO:0045216 cell-cell junction organization(GO:0045216)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.7 2.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 2.7 GO:0008537 proteasome activator complex(GO:0008537)
0.4 2.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 4.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 4.6 GO:0000145 exocyst(GO:0000145)
0.2 3.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.8 GO:0032021 NELF complex(GO:0032021)
0.2 2.6 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.7 GO:0000800 lateral element(GO:0000800)
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.9 GO:0005839 proteasome core complex(GO:0005839)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.9 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 4.4 GO:0005643 nuclear pore(GO:0005643)
0.1 0.2 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 1.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.5 GO:0005657 replication fork(GO:0005657)
0.0 2.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 2.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.5 1.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.4 1.2 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.3 2.8 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.3 5.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 2.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 0.9 GO:0009881 photoreceptor activity(GO:0009881)
0.3 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 3.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 1.8 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.7 GO:0000150 recombinase activity(GO:0000150)
0.2 0.7 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 0.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.0 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 4.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385)
0.1 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.3 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.1 2.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 1.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126) pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 6.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 1.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.2 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 3.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 5.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 7.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 0.9 PID_ALK2_PATHWAY ALK2 signaling events
0.1 3.1 PID_ATR_PATHWAY ATR signaling pathway
0.1 2.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 0.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.7 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.7 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.5 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.2 2.5 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.2 2.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 3.0 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 1.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.7 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 3.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 3.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.5 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.0 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.9 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.9 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 3.6 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 1.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.0 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 6.7 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 0.5 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.7 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.4 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus