Motif ID: Spic
Z-value: 0.690

Transcription factors associated with Spic:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Spic | ENSMUSG00000004359.10 | Spic |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Spic | mm10_v2_chr10_-_88683021_88683025 | 0.15 | 5.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:0032240 | mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
0.2 | 0.7 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.2 | 1.6 | GO:0071569 | protein ufmylation(GO:0071569) |
0.2 | 1.7 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.2 | 0.5 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.1 | 0.6 | GO:0050904 | diapedesis(GO:0050904) |
0.1 | 0.4 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
0.1 | 0.7 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
0.1 | 0.8 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.1 | 0.4 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.1 | 0.5 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) |
0.1 | 0.4 | GO:2001180 | negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180) |
0.1 | 0.4 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
0.1 | 0.4 | GO:1902220 | positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220) |
0.1 | 0.4 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
0.1 | 0.3 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.1 | 0.6 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
0.1 | 0.5 | GO:0035617 | stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150) |
0.1 | 0.3 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
0.1 | 0.3 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
0.1 | 0.3 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
0.1 | 0.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 0.3 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.1 | 0.4 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
0.1 | 0.3 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.1 | 0.6 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.1 | 0.1 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
0.1 | 0.1 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
0.1 | 0.3 | GO:0032796 | uropod organization(GO:0032796) |
0.1 | 0.2 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
0.1 | 0.2 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.1 | 0.1 | GO:0033864 | positive regulation of NAD(P)H oxidase activity(GO:0033864) |
0.1 | 0.2 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
0.0 | 0.1 | GO:1900673 | olefin metabolic process(GO:1900673) |
0.0 | 0.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.0 | 0.3 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.0 | 0.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.0 | 0.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.0 | 0.1 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
0.0 | 0.1 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289) |
0.0 | 0.1 | GO:1904959 | regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
0.0 | 0.6 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 0.3 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 0.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
0.0 | 0.1 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.0 | 0.4 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.0 | 0.7 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.0 | 0.1 | GO:1904809 | dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811) |
0.0 | 0.2 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.0 | 0.2 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
0.0 | 0.4 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.0 | 0.1 | GO:0045869 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) |
0.0 | 0.7 | GO:0007035 | vacuolar acidification(GO:0007035) |
0.0 | 0.1 | GO:0090024 | negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) |
0.0 | 0.4 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.0 | 0.2 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.1 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.0 | 0.1 | GO:1905076 | regulation of interleukin-17 secretion(GO:1905076) positive regulation of T-helper 17 type immune response(GO:2000318) |
0.0 | 0.2 | GO:1901911 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.3 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.0 | 0.2 | GO:0007195 | adenosine receptor signaling pathway(GO:0001973) adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
0.0 | 0.3 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
0.0 | 0.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.1 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.0 | 0.1 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.0 | 0.4 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
0.0 | 0.6 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
0.0 | 0.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.1 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.0 | 0.1 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
0.0 | 0.1 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.0 | 0.1 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.0 | 0.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.0 | 0.3 | GO:0015816 | glycine transport(GO:0015816) |
0.0 | 0.1 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.0 | 0.3 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.2 | GO:0051014 | actin filament severing(GO:0051014) |
0.0 | 0.3 | GO:0016559 | peroxisome fission(GO:0016559) |
0.0 | 0.2 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.0 | 0.1 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.0 | 0.6 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 0.1 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
0.0 | 0.3 | GO:0003413 | chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) |
0.0 | 0.1 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
0.0 | 0.2 | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
0.0 | 0.1 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
0.0 | 0.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.1 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 0.1 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.0 | 0.4 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.0 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.0 | 0.3 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.3 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.0 | 0.1 | GO:0051013 | microtubule severing(GO:0051013) |
0.0 | 0.2 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
0.0 | 0.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.2 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.1 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.0 | 0.2 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.1 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.0 | 0.0 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.0 | 0.2 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.0 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
0.0 | 0.2 | GO:0006298 | mismatch repair(GO:0006298) |
0.0 | 0.1 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
0.0 | 0.5 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 0.6 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.3 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.2 | 1.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.2 | 0.8 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.2 | 0.7 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
0.2 | 0.5 | GO:0035061 | interchromatin granule(GO:0035061) |
0.2 | 0.5 | GO:0099631 | postsynaptic endocytic zone cytoplasmic component(GO:0099631) |
0.1 | 0.8 | GO:1990393 | 3M complex(GO:1990393) |
0.1 | 0.4 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
0.1 | 0.6 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 0.7 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 0.6 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
0.1 | 0.5 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.1 | 0.3 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.1 | 0.4 | GO:0070820 | tertiary granule(GO:0070820) |
0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.1 | 0.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 0.5 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 0.6 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.1 | 0.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.1 | 0.2 | GO:0097651 | phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
0.1 | 0.8 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.2 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
0.0 | 0.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.0 | 0.3 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.0 | 0.1 | GO:0055087 | Ski complex(GO:0055087) |
0.0 | 2.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.9 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.1 | GO:0044307 | dendritic branch(GO:0044307) |
0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
0.0 | 0.3 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 0.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 1.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.2 | GO:0042581 | specific granule(GO:0042581) |
0.0 | 0.4 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.2 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.1 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.0 | 0.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.0 | 0.3 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.1 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 0.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 0.4 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.6 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.2 | 1.7 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.2 | 0.7 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
0.2 | 0.5 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.1 | 0.4 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.1 | 0.6 | GO:0070051 | fibrinogen binding(GO:0070051) |
0.1 | 0.7 | GO:0016936 | galactoside binding(GO:0016936) |
0.1 | 0.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 0.5 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.1 | 0.6 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
0.1 | 0.7 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.1 | 0.4 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
0.1 | 0.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.4 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.1 | 0.7 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.1 | 0.2 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
0.1 | 1.0 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 0.1 | GO:0001179 | RNA polymerase I transcription factor binding(GO:0001179) |
0.1 | 0.5 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.1 | 0.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 1.0 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.1 | 0.3 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.0 | 0.1 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.0 | 0.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 0.1 | GO:0004875 | complement receptor activity(GO:0004875) |
0.0 | 0.6 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
0.0 | 0.2 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.0 | 0.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 1.2 | GO:0070840 | dynein complex binding(GO:0070840) |
0.0 | 0.1 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.0 | 0.3 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.0 | 0.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.0 | 0.4 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
0.0 | 0.1 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 0.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 0.2 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.1 | GO:0005118 | sevenless binding(GO:0005118) |
0.0 | 0.3 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.3 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
0.0 | 0.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 0.1 | GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.0 | 0.2 | GO:0034711 | inhibin binding(GO:0034711) |
0.0 | 0.8 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.0 | 0.1 | GO:0097001 | ceramide binding(GO:0097001) |
0.0 | 0.1 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 3.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.0 | 0.1 | GO:0089720 | caspase binding(GO:0089720) |
0.0 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 0.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.2 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.0 | 0.1 | GO:0051425 | PTB domain binding(GO:0051425) |
0.0 | 0.1 | GO:0016531 | copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136) |
0.0 | 0.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.0 | 0.2 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.3 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 0.2 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.1 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.0 | 0.1 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.2 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.8 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
0.0 | 0.2 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.0 | 0.4 | GO:0050699 | WW domain binding(GO:0050699) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.1 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.4 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.0 | 0.8 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.2 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 1.1 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 1.0 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.2 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.6 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.7 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.1 | 0.2 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 0.3 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 1.3 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 0.1 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 0.6 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.0 | 0.5 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 1.9 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.6 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
0.0 | 0.3 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
0.0 | 1.0 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
0.0 | 0.2 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.0 | 0.5 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 0.2 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
0.0 | 0.5 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.5 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.3 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 1.5 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.2 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.0 | 0.2 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.0 | 0.1 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PI | Genes involved in Acyl chain remodelling of PI |
0.0 | 0.1 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.2 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 0.3 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.4 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
0.0 | 0.4 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.3 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.5 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
0.0 | 0.7 | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |