Motif ID: Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 7.218


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ybx1mm10_v2_chr4_-_119294520_1192946040.771.9e-04Click!
Nfybmm10_v2_chr10_-_82764088_82764144-0.701.2e-03Click!
Cebpzmm10_v2_chr17_-_78937031_78937074-0.493.7e-02Click!
Nfycmm10_v2_chr4_-_120815703_1208157610.456.2e-02Click!
Nfyamm10_v2_chr17_-_48409729_48409906-0.322.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_124829582 25.617 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr8_+_83955507 22.273 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr16_-_17125106 21.764 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr3_-_89418287 18.237 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr13_-_23745511 17.490 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr6_+_124829540 16.878 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr3_-_8667033 16.820 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr6_+_124830217 16.107 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr8_+_57511833 14.814 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr14_+_46760526 14.559 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chrX_+_58030622 14.197 ENSMUST00000088627.4
Zic3
zinc finger protein of the cerebellum 3
chr2_+_34772089 13.982 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr11_-_87108656 13.881 ENSMUST00000051395.8
Prr11
proline rich 11
chr14_+_19751257 13.591 ENSMUST00000022340.3
Nid2
nidogen 2
chr13_-_56252163 12.901 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr11_+_54902743 12.857 ENSMUST00000082430.3
Gpx3
glutathione peroxidase 3
chr17_-_24251382 12.286 ENSMUST00000115390.3
Ccnf
cyclin F
chr11_+_95337012 12.284 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr16_+_30065333 12.149 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr7_-_120982260 12.067 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr2_+_164769892 12.049 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr3_-_27153861 11.408 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr8_-_94918012 10.828 ENSMUST00000077955.5
Ccdc102a
coiled-coil domain containing 102A
chr13_-_24761440 10.727 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chr3_-_27153844 10.696 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr16_+_14163275 10.694 ENSMUST00000023359.6
ENSMUST00000117958.1
Nde1

nuclear distribution gene E homolog 1 (A nidulans)

chr6_-_82774448 10.689 ENSMUST00000000642.4
Hk2
hexokinase 2
chr1_+_131527901 10.628 ENSMUST00000068613.4
Fam72a
family with sequence similarity 72, member A
chr16_+_14163316 10.541 ENSMUST00000115795.2
Nde1
nuclear distribution gene E homolog 1 (A nidulans)
chr4_-_124936852 10.503 ENSMUST00000030690.5
ENSMUST00000084296.3
Cdca8

cell division cycle associated 8

chr7_-_4752972 10.493 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr6_+_29694204 10.470 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr11_-_99024179 10.317 ENSMUST00000068031.7
Top2a
topoisomerase (DNA) II alpha
chr11_-_94474088 10.284 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr5_-_106458440 10.243 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr13_-_24761861 10.230 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr11_-_84525514 10.071 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr13_+_51645232 10.041 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr5_+_114130386 9.960 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr9_-_70421533 9.811 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr2_-_172370506 9.545 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chrX_+_58030999 9.525 ENSMUST00000088631.4
ENSMUST00000088629.3
Zic3

zinc finger protein of the cerebellum 3

chr8_+_23411490 9.510 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr1_+_184034381 9.501 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr11_+_40733639 9.497 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr11_-_97187872 9.369 ENSMUST00000001479.4
Kpnb1
karyopherin (importin) beta 1
chr7_-_48881596 9.339 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr18_-_61707583 9.293 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr11_+_87109221 9.214 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2
chr4_+_132768325 9.155 ENSMUST00000102561.4
Rpa2
replication protein A2
chr12_-_99883429 9.075 ENSMUST00000046485.3
Efcab11
EF-hand calcium binding domain 11
chr13_+_23535411 9.056 ENSMUST00000080859.5
Hist1h3g
histone cluster 1, H3g
chr10_-_69352886 8.901 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1

cyclin-dependent kinase 1

chr5_+_30666886 8.891 ENSMUST00000144742.1
Cenpa
centromere protein A
chr11_-_106999482 8.835 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr19_+_44493472 8.834 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr1_+_191821444 8.714 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr15_+_99074968 8.677 ENSMUST00000039665.6
Troap
trophinin associated protein
chr7_-_143460989 8.585 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr17_+_56304313 8.570 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr3_+_32708546 8.565 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr17_-_56830916 8.525 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr9_-_91365778 8.521 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr1_+_132316112 8.514 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr11_-_120572822 8.507 ENSMUST00000168360.1
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr9_-_44113470 8.458 ENSMUST00000056328.5
Rnf26
ring finger protein 26
chr11_+_72042455 8.425 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr2_+_25372315 8.321 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr10_-_128821576 8.319 ENSMUST00000026409.3
Ormdl2
ORM1-like 2 (S. cerevisiae)
chr13_-_23762378 8.180 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr1_-_184033998 8.162 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr11_-_78550777 8.075 ENSMUST00000103242.4
Tmem97
transmembrane protein 97
chr11_+_40733936 8.022 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr11_-_106999369 8.006 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr14_+_55824795 7.968 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr5_+_33658123 7.962 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr9_+_83834684 7.936 ENSMUST00000070326.7
Ttk
Ttk protein kinase
chr18_+_34625009 7.876 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr9_-_91365756 7.849 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chr2_-_119618455 7.847 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr11_+_84525669 7.819 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr13_-_53473074 7.799 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr19_-_7039987 7.756 ENSMUST00000025918.7
Stip1
stress-induced phosphoprotein 1
chr2_-_127831817 7.752 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr5_+_33658567 7.744 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr4_-_118437331 7.736 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr14_-_52104015 7.687 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr2_-_144011202 7.671 ENSMUST00000016072.5
ENSMUST00000037875.5
Rrbp1

ribosome binding protein 1

chr14_-_19823807 7.644 ENSMUST00000022341.5
2700060E02Rik
RIKEN cDNA 2700060E02 gene
chr7_+_16781341 7.548 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_+_69045640 7.532 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr12_-_110978981 7.532 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr11_+_54902917 7.429 ENSMUST00000149324.1
Gpx3
glutathione peroxidase 3
chr5_+_110839973 7.420 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr7_-_48881032 7.403 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr6_-_125191535 7.389 ENSMUST00000043848.4
Ncapd2
non-SMC condensin I complex, subunit D2
chr19_-_9899450 7.362 ENSMUST00000025562.7
Incenp
inner centromere protein
chr5_-_37824580 7.348 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr7_+_79660196 7.336 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr4_+_109978004 7.334 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr5_+_120431770 7.307 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr10_-_81350305 7.272 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr10_+_128821745 7.261 ENSMUST00000105230.2
Sarnp
SAP domain containing ribonucleoprotein
chr18_-_77047243 7.211 ENSMUST00000137354.1
ENSMUST00000137498.1
Katnal2

katanin p60 subunit A-like 2

chr17_-_35516780 7.149 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr14_-_67715585 7.148 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr11_+_112782182 7.137 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr7_-_17062384 7.110 ENSMUST00000153833.1
ENSMUST00000108492.2
Hif3a

hypoxia inducible factor 3, alpha subunit

chr18_-_33213832 7.077 ENSMUST00000025236.2
Stard4
StAR-related lipid transfer (START) domain containing 4
chr3_+_96219858 7.047 ENSMUST00000073115.4
Hist2h2ab
histone cluster 2, H2ab
chr4_+_106561027 7.031 ENSMUST00000047973.3
Dhcr24
24-dehydrocholesterol reductase
chr13_+_104229366 6.932 ENSMUST00000022227.6
Cenpk
centromere protein K
chr3_-_27153782 6.918 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr17_-_24886304 6.885 ENSMUST00000044252.5
Nubp2
nucleotide binding protein 2
chr19_-_15924928 6.848 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr17_-_34000257 6.822 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr14_+_67716095 6.793 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr13_+_104228929 6.761 ENSMUST00000070761.3
Cenpk
centromere protein K
chr3_+_96269695 6.759 ENSMUST00000051089.3
ENSMUST00000177113.1
Hist2h2bb

histone cluster 2, H2bb

chr9_+_65890237 6.735 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr2_+_119618717 6.719 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr4_-_43000451 6.713 ENSMUST00000030164.7
Vcp
valosin containing protein
chr2_-_30474199 6.693 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr18_-_34751502 6.690 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr11_-_75348261 6.678 ENSMUST00000000767.5
ENSMUST00000092907.5
Rpa1

replication protein A1

chr1_-_171196229 6.676 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr2_-_154569845 6.674 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr13_-_116309639 6.613 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr7_-_49636847 6.604 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr7_+_141215852 6.596 ENSMUST00000046890.5
ENSMUST00000133763.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr5_+_136084022 6.588 ENSMUST00000100570.3
Rasa4
RAS p21 protein activator 4
chr10_-_30842765 6.542 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr11_-_102925086 6.495 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr2_+_152847961 6.468 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr7_+_35397046 6.443 ENSMUST00000079414.5
Cep89
centrosomal protein 89
chrX_-_133688978 6.402 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr17_-_63863791 6.339 ENSMUST00000050753.3
A930002H24Rik
RIKEN cDNA A930002H24 gene
chr5_+_33658550 6.289 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr2_+_152847993 6.262 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr14_+_21052574 6.234 ENSMUST00000045376.9
Adk
adenosine kinase
chrX_+_73639414 6.216 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr1_+_134962553 6.216 ENSMUST00000027687.7
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr2_-_168767136 6.210 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr3_+_137864487 6.203 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr3_+_95929246 6.202 ENSMUST00000165307.1
ENSMUST00000015893.6
Anp32e

acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

chr6_-_67037399 6.189 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr10_-_81350389 6.181 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr11_+_84525647 6.181 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr5_+_136083916 6.173 ENSMUST00000042135.7
Rasa4
RAS p21 protein activator 4
chr19_-_46044914 6.144 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr13_+_21717626 6.123 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr4_-_120815703 6.114 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr14_+_99046406 6.028 ENSMUST00000022656.6
Bora
bora, aurora kinase A activator
chr9_-_111271568 6.012 ENSMUST00000035079.3
Mlh1
mutL homolog 1 (E. coli)
chr2_-_154569720 6.009 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr11_-_120573253 5.998 ENSMUST00000026122.4
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr11_+_68968107 5.996 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr13_+_8885501 5.985 ENSMUST00000169314.2
Idi1
isopentenyl-diphosphate delta isomerase
chr13_+_23544052 5.966 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr16_-_18811615 5.959 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr6_-_87851074 5.951 ENSMUST00000032138.8
ENSMUST00000113619.1
Cnbp

cellular nucleic acid binding protein

chr5_+_114444266 5.940 ENSMUST00000043760.8
ENSMUST00000112239.2
ENSMUST00000125650.1
Mvk


mevalonate kinase


chr6_-_85451248 5.910 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr10_-_81350191 5.899 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr18_+_34624621 5.874 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr9_-_106891870 5.862 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
Manf


mesencephalic astrocyte-derived neurotrophic factor


chr3_+_137864573 5.841 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr1_+_169969409 5.838 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr12_+_111814170 5.826 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr2_+_157279026 5.821 ENSMUST00000116380.2
Rpn2
ribophorin II
chr17_-_12960729 5.815 ENSMUST00000007005.7
Acat2
acetyl-Coenzyme A acetyltransferase 2
chr2_+_157279065 5.806 ENSMUST00000029171.5
Rpn2
ribophorin II
chr5_-_149053038 5.768 ENSMUST00000085546.6
Hmgb1
high mobility group box 1
chr1_-_138619687 5.745 ENSMUST00000027642.2
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr7_+_27486910 5.730 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr7_+_122159422 5.721 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chr15_-_79062866 5.683 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr9_-_106891965 5.669 ENSMUST00000159283.1
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr16_-_18811972 5.661 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr4_-_132510493 5.653 ENSMUST00000030724.8
Sesn2
sestrin 2
chr13_-_23562369 5.556 ENSMUST00000105107.1
Hist1h3e
histone cluster 1, H3e
chr13_+_117220584 5.536 ENSMUST00000022242.7
Emb
embigin
chrX_-_93832106 5.529 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr11_+_119022962 5.468 ENSMUST00000026662.7
Cbx2
chromobox 2
chr2_-_69206146 5.435 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr7_+_28810886 5.435 ENSMUST00000038572.8
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr2_+_166906026 5.427 ENSMUST00000002790.7
Cse1l
chromosome segregation 1-like (S. cerevisiae)
chr5_-_114690974 5.424 ENSMUST00000012028.7
Gltp
glycolipid transfer protein
chr2_-_25224653 5.412 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr11_-_6444352 5.405 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr2_-_69206133 5.405 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr9_+_44334685 5.404 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr18_-_77047282 5.399 ENSMUST00000154665.1
ENSMUST00000026486.6
ENSMUST00000123650.1
ENSMUST00000126153.1
Katnal2



katanin p60 subunit A-like 2



chr12_-_83921899 5.343 ENSMUST00000117217.1
Numb
numb gene homolog (Drosophila)
chr17_+_43667389 5.330 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr6_-_47813512 5.310 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr2_-_132253227 5.248 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr8_+_75033673 5.245 ENSMUST00000078847.5
ENSMUST00000165630.1
Tom1

target of myb1 homolog (chicken)

chr14_-_8666236 5.237 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr5_+_124439891 5.214 ENSMUST00000059580.4
Setd8
SET domain containing (lysine methyltransferase) 8

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 40.9 GO:0072049 comma-shaped body morphogenesis(GO:0072049)
5.7 17.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
5.0 15.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
4.7 14.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
4.3 13.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
4.3 12.9 GO:1903334 positive regulation of protein folding(GO:1903334)
4.2 12.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
4.2 33.3 GO:0016321 female meiosis chromosome segregation(GO:0016321)
4.1 8.2 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
4.0 23.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
3.9 11.6 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.8 11.5 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
3.7 11.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
3.6 7.1 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
3.6 24.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
3.4 10.1 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
3.3 10.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
3.2 9.5 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
3.1 9.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
3.0 11.9 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
2.9 8.8 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
2.8 8.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.8 14.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
2.8 8.3 GO:0019401 alditol biosynthetic process(GO:0019401)
2.8 11.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
2.7 16.4 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
2.7 5.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
2.7 8.1 GO:0032474 otolith morphogenesis(GO:0032474)
2.7 83.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
2.7 8.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
2.6 7.8 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
2.6 10.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
2.5 10.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
2.4 14.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
2.3 4.6 GO:0072199 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
2.3 11.5 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
2.3 9.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
2.2 6.7 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
2.2 6.6 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
2.2 6.5 GO:0003195 tricuspid valve formation(GO:0003195)
2.2 8.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
2.2 15.2 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
2.1 21.4 GO:0051255 spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
2.1 6.2 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
2.0 14.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
2.0 12.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
2.0 6.0 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
1.9 5.8 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
1.9 7.7 GO:0090365 regulation of mRNA modification(GO:0090365)
1.9 5.7 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.9 3.8 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
1.9 7.4 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
1.8 27.7 GO:0007100 mitotic centrosome separation(GO:0007100)
1.8 22.0 GO:0030953 astral microtubule organization(GO:0030953)
1.8 3.6 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.8 3.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.8 8.9 GO:0006868 glutamine transport(GO:0006868)
1.8 5.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7 17.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
1.7 6.9 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.7 10.1 GO:0000279 M phase(GO:0000279)
1.7 5.0 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.7 46.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
1.7 3.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.6 11.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.6 3.2 GO:0030222 eosinophil differentiation(GO:0030222)
1.6 4.7 GO:0036292 DNA rewinding(GO:0036292)
1.5 4.6 GO:0007290 spermatid nucleus elongation(GO:0007290)
1.5 6.2 GO:0006272 leading strand elongation(GO:0006272)
1.5 6.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.5 13.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
1.5 6.1 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.5 4.5 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
1.5 4.4 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
1.5 8.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.5 7.3 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.4 4.3 GO:0061198 fungiform papilla formation(GO:0061198)
1.4 11.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.4 17.0 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
1.4 17.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.4 2.8 GO:0060066 oviduct development(GO:0060066)
1.4 28.2 GO:0043486 histone exchange(GO:0043486)
1.4 8.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
1.4 4.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
1.4 5.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.3 4.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.3 17.1 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
1.3 32.7 GO:0006270 DNA replication initiation(GO:0006270)
1.3 6.5 GO:1990839 response to endothelin(GO:1990839)
1.3 15.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.3 3.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
1.3 3.8 GO:0042637 catagen(GO:0042637)
1.3 8.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.3 25.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
1.2 5.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.2 3.7 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
1.2 6.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.2 11.0 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
1.2 7.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
1.2 3.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.2 3.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
1.2 3.5 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
1.2 10.6 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.2 4.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
1.2 7.0 GO:0033504 floor plate development(GO:0033504)
1.2 17.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
1.2 2.3 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
1.1 3.4 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
1.1 5.5 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
1.1 13.1 GO:0030539 male genitalia development(GO:0030539)
1.1 5.4 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.1 14.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
1.1 12.6 GO:0002227 innate immune response in mucosa(GO:0002227)
1.1 5.3 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
1.0 8.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.0 10.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.0 7.2 GO:0070092 regulation of glucagon secretion(GO:0070092)
1.0 8.2 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
1.0 1.0 GO:0051660 establishment of centrosome localization(GO:0051660)
1.0 5.0 GO:0007386 compartment pattern specification(GO:0007386)
1.0 5.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.0 3.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.0 4.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
1.0 5.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.0 3.9 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.9 2.8 GO:0042732 D-xylose metabolic process(GO:0042732)
0.9 1.9 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.9 22.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.9 1.8 GO:0006407 rRNA export from nucleus(GO:0006407)
0.9 1.8 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.9 2.8 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.9 3.6 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.9 6.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.9 2.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.9 6.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.9 2.7 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.9 9.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.9 3.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.9 3.5 GO:0071609 chemokine (C-C motif) ligand 5 production(GO:0071609)
0.9 10.6 GO:0030238 male sex determination(GO:0030238)
0.9 4.3 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.9 2.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.9 6.0 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.8 4.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.8 1.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.8 1.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8 13.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.8 0.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.8 2.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.8 8.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.8 2.4 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.8 7.3 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.8 4.8 GO:0000733 DNA strand renaturation(GO:0000733)
0.8 0.8 GO:0051299 centrosome separation(GO:0051299)
0.8 16.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.8 3.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.8 3.9 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.8 3.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.8 4.6 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.8 3.1 GO:0015888 thiamine transport(GO:0015888)
0.8 6.2 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.8 1.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.8 2.3 GO:0021759 globus pallidus development(GO:0021759)
0.8 33.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.8 2.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.7 17.1 GO:0006298 mismatch repair(GO:0006298)
0.7 2.2 GO:0006553 lysine metabolic process(GO:0006553)
0.7 5.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.7 2.9 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.7 2.9 GO:1905065 regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.7 2.9 GO:0030202 heparin metabolic process(GO:0030202)
0.7 9.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.7 4.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.7 65.1 GO:0006342 chromatin silencing(GO:0006342)
0.7 1.4 GO:0006106 fumarate metabolic process(GO:0006106)
0.7 7.7 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.7 4.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.7 2.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.7 2.8 GO:0034214 protein hexamerization(GO:0034214)
0.7 8.9 GO:0001675 acrosome assembly(GO:0001675)
0.7 4.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.7 2.1 GO:0042908 xenobiotic transport(GO:0042908)
0.7 4.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.7 2.0 GO:1905223 epicardium morphogenesis(GO:1905223)
0.7 3.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.7 2.6 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.6 7.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.6 1.9 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.6 1.9 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.6 6.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.6 3.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.6 1.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.6 3.0 GO:0048665 neuron fate specification(GO:0048665)
0.6 1.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.6 4.8 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.6 12.1 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.6 2.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.6 14.4 GO:0001709 cell fate determination(GO:0001709)
0.6 0.6 GO:0009106 lipoate metabolic process(GO:0009106)
0.6 2.4 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.6 2.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 3.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.6 1.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.6 1.7 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.6 2.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.6 1.7 GO:1904874 positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.6 3.4 GO:0060290 transdifferentiation(GO:0060290)
0.6 11.2 GO:0007099 centriole replication(GO:0007099)
0.6 3.9 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.6 6.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.6 5.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.6 1.7 GO:0043686 co-translational protein modification(GO:0043686)
0.6 3.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.6 4.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 3.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 1.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 2.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 3.8 GO:0060056 mammary gland involution(GO:0060056)
0.5 3.2 GO:0070836 caveola assembly(GO:0070836)
0.5 2.6 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.5 1.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5 1.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.5 0.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.5 16.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.5 2.0 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.5 1.5 GO:0019323 pentose catabolic process(GO:0019323)
0.5 0.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.5 1.0 GO:0072143 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.5 1.5 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.5 4.4 GO:0051310 metaphase plate congression(GO:0051310)
0.5 9.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.5 1.0 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.5 7.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.5 3.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 1.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.5 3.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.5 2.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.5 1.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.5 6.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.5 3.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.5 2.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.5 2.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.5 5.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.4 3.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 0.9 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 2.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 1.3 GO:0045590 positive regulation of interleukin-12 biosynthetic process(GO:0045084) negative regulation of regulatory T cell differentiation(GO:0045590)
0.4 1.3 GO:0072050 S-shaped body morphogenesis(GO:0072050)
0.4 4.9 GO:0051451 myoblast migration(GO:0051451)
0.4 1.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.4 7.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.4 0.9 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.4 2.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.4 0.9 GO:0072719 cellular response to cisplatin(GO:0072719)
0.4 12.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.4 2.2 GO:0006108 malate metabolic process(GO:0006108)
0.4 6.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.4 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 1.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 2.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.4 21.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.4 3.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 4.6 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.4 1.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.4 1.6 GO:0030091 protein repair(GO:0030091)
0.4 4.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 0.4 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.4 1.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.4 1.6 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239)
0.4 1.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 1.6 GO:0002339 B cell selection(GO:0002339)
0.4 5.6 GO:0030220 platelet formation(GO:0030220)
0.4 8.4 GO:0045116 protein neddylation(GO:0045116)
0.4 0.8 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.4 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.4 5.4 GO:0006465 signal peptide processing(GO:0006465)
0.4 5.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.4 2.7 GO:0044241 lipid digestion(GO:0044241)
0.4 2.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 1.5 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.4 1.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.4 0.4 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.4 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.4 8.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.4 1.5 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.4 1.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.4 2.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.4 3.7 GO:0018065 protein-cofactor linkage(GO:0018065)
0.4 0.7 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.4 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 1.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.4 2.9 GO:0043589 skin morphogenesis(GO:0043589)
0.4 0.7 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.4 4.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.4 0.4 GO:0051026 chiasma assembly(GO:0051026)
0.4 1.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.4 9.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 1.8 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 2.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.3 1.7 GO:0033762 response to glucagon(GO:0033762)
0.3 1.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 0.7 GO:0071455 response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.3 0.3 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.3 3.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.6 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.3 3.9 GO:0060736 prostate gland growth(GO:0060736)
0.3 8.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.3 1.0 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121)
0.3 1.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 4.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3 0.3 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.3 1.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 4.4 GO:0043248 proteasome assembly(GO:0043248)
0.3 0.9 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 0.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 1.2 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.3 10.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.7 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.3 1.5 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 0.9 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.3 3.3 GO:0060539 diaphragm development(GO:0060539)
0.3 2.1 GO:0007530 sex determination(GO:0007530)
0.3 2.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 1.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 0.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.3 6.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 1.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 1.7 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.3 0.9 GO:0042823 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 1.4 GO:0002467 germinal center formation(GO:0002467)
0.3 4.9 GO:0016556 mRNA modification(GO:0016556)
0.3 4.0 GO:0042407 cristae formation(GO:0042407)
0.3 5.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.3 1.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.3 1.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.3 0.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.3 1.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.3 17.7 GO:0006334 nucleosome assembly(GO:0006334)
0.3 2.8 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 0.6 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.3 1.9 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.3 0.5 GO:0090670 RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672)
0.3 0.8 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.3 0.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 2.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 0.8 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 4.8 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.3 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.3 1.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 1.6 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.3 0.8 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.3 2.1 GO:0006477 protein sulfation(GO:0006477)
0.3 4.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 1.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3 4.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.3 0.3 GO:2000823 regulation of androgen receptor activity(GO:2000823) positive regulation of androgen receptor activity(GO:2000825)
0.3 0.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 2.3 GO:0031639 plasminogen activation(GO:0031639)
0.3 0.5 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 2.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.2 1.0 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.2 1.7 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.2 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 3.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 0.7 GO:0036490 regulation of translation in response to endoplasmic reticulum stress(GO:0036490)
0.2 1.2 GO:0019236 response to pheromone(GO:0019236)
0.2 2.1 GO:0030049 muscle filament sliding(GO:0030049)
0.2 3.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 2.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 8.5 GO:0043029 T cell homeostasis(GO:0043029)
0.2 0.5 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 1.4 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.2 3.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.4 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 0.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 0.7 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.2 2.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 2.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 4.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 1.5 GO:0034508 centromere complex assembly(GO:0034508)
0.2 8.8 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.2 0.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 1.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 2.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.3 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.2 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 0.8 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 12.3 GO:0042307 positive regulation of protein import into nucleus(GO:0042307)
0.2 0.2 GO:0021747 cochlear nucleus development(GO:0021747)
0.2 3.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2 0.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 2.5 GO:0007398 ectoderm development(GO:0007398)
0.2 3.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 1.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 4.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 1.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 1.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.4 GO:0006551 leucine metabolic process(GO:0006551)
0.2 2.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 28.0 GO:0006457 protein folding(GO:0006457)
0.2 1.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 7.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.4 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.2 1.7 GO:0021511 spinal cord patterning(GO:0021511)
0.2 0.4 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 0.9 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 1.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 0.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 3.3 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.2 0.7 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 0.4 GO:0002922 positive regulation of humoral immune response(GO:0002922)
0.2 2.7 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.2 2.5 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.2 3.1 GO:0060972 left/right pattern formation(GO:0060972)
0.2 8.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 1.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.2 3.5 GO:0016180 snRNA processing(GO:0016180)
0.2 5.3 GO:0048477 oogenesis(GO:0048477)
0.2 0.7 GO:0003177 pulmonary valve development(GO:0003177) pulmonary valve morphogenesis(GO:0003184)
0.2 0.5 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 6.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 0.8 GO:0048102 autophagic cell death(GO:0048102)
0.2 10.0 GO:0007050 cell cycle arrest(GO:0007050)
0.2 3.1 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.2 0.5 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 3.3 GO:0006301 postreplication repair(GO:0006301)
0.2 0.6 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 1.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 3.6 GO:0070207 protein homotrimerization(GO:0070207)
0.2 2.8 GO:0019835 cytolysis(GO:0019835)
0.2 1.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 2.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.6 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550)
0.1 4.6 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 1.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.5 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.1 1.6 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 1.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.1 1.9 GO:0006833 water transport(GO:0006833)
0.1 1.4 GO:0071426 ribonucleoprotein complex export from nucleus(GO:0071426)
0.1 0.9 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 0.7 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 2.1 GO:0034453 microtubule anchoring(GO:0034453)
0.1 2.2 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.1 4.5 GO:0006805 xenobiotic metabolic process(GO:0006805) cellular response to xenobiotic stimulus(GO:0071466)
0.1 3.8 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 6.8 GO:0051028 mRNA transport(GO:0051028)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 7.7 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.1 GO:0031295 T cell costimulation(GO:0031295)
0.1 1.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 3.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 2.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.4 GO:0007602 phototransduction(GO:0007602)
0.1 0.4 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) benzene-containing compound metabolic process(GO:0042537) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.1 0.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.1 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 0.7 GO:0008272 sulfate transport(GO:0008272)
0.1 0.7 GO:0006972 hyperosmotic response(GO:0006972)
0.1 3.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.9 GO:0006415 translational termination(GO:0006415)
0.1 1.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 1.6 GO:0006907 pinocytosis(GO:0006907)
0.1 3.5 GO:0030901 midbrain development(GO:0030901)
0.1 0.6 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.1 1.8 GO:0014002 astrocyte development(GO:0014002)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.8 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.1 0.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 1.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 1.6 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 1.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 1.0 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1 3.7 GO:0006414 translational elongation(GO:0006414)
0.1 1.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.6 GO:0001947 heart looping(GO:0001947)
0.1 1.6 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.6 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.8 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.1 0.5 GO:0046208 spermine catabolic process(GO:0046208)
0.1 2.0 GO:0006821 chloride transport(GO:0006821)
0.1 0.2 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 0.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 8.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.7 GO:0001841 neural tube formation(GO:0001841)
0.1 0.1 GO:0006404 RNA import into nucleus(GO:0006404)
0.1 0.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.7 GO:0006760 folic acid-containing compound metabolic process(GO:0006760)
0.1 1.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 6.7 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.1 0.2 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.0 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.1 2.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 3.0 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.1 1.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 1.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 0.1 GO:0021678 third ventricle development(GO:0021678)
0.1 1.9 GO:0006284 base-excision repair(GO:0006284)
0.1 1.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.1 GO:1904528 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1 0.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.3 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 4.8 GO:0009408 response to heat(GO:0009408)
0.1 2.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 1.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.2 GO:0061371 determination of heart left/right asymmetry(GO:0061371)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 1.3 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 6.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 2.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.9 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1 1.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 8.5 GO:0051604 protein maturation(GO:0051604)
0.1 0.9 GO:0035329 hippo signaling(GO:0035329)
0.1 0.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 1.7 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 0.1 GO:0061743 motor learning(GO:0061743)
0.1 1.8 GO:1901998 toxin transport(GO:1901998)
0.1 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.1 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)
0.1 2.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 22.5 GO:0051301 cell division(GO:0051301)
0.1 0.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.4 GO:0019081 viral translation(GO:0019081)
0.1 1.2 GO:0000154 rRNA modification(GO:0000154)
0.1 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.1 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 0.6 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.2 GO:0060323 head morphogenesis(GO:0060323)
0.1 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.0 GO:0046148 pigment biosynthetic process(GO:0046148)
0.1 0.6 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.4 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 1.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.8 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.6 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 1.8 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.2 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.0 0.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 2.2 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.1 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.3 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.4 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.5 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.4 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.3 GO:0043627 response to estrogen(GO:0043627)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0003170 heart valve development(GO:0003170)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.3 GO:0060425 lung morphogenesis(GO:0060425)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.0 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.5 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.0 GO:0060438 trachea development(GO:0060438)
0.0 0.0 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.0 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 33.6 GO:0097149 centralspindlin complex(GO:0097149)
5.5 27.6 GO:0032133 chromosome passenger complex(GO:0032133)
4.8 19.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
4.5 17.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
4.2 54.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
3.9 11.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
3.6 10.9 GO:0000799 nuclear condensin complex(GO:0000799)
3.5 3.5 GO:0042585 germinal vesicle(GO:0042585)
3.3 13.0 GO:0035339 SPOTS complex(GO:0035339)
2.8 14.2 GO:0031262 Ndc80 complex(GO:0031262)
2.6 5.1 GO:0097431 mitotic spindle pole(GO:0097431)
2.5 10.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.5 12.7 GO:0035189 Rb-E2F complex(GO:0035189)
2.5 7.4 GO:0000801 central element(GO:0000801)
2.4 19.2 GO:0005818 aster(GO:0005818)
2.2 38.1 GO:0031616 spindle pole centrosome(GO:0031616)
2.2 6.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
2.0 6.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
2.0 6.0 GO:0033186 CAF-1 complex(GO:0033186)
1.9 5.8 GO:0005584 collagen type I trimer(GO:0005584)
1.8 128.7 GO:0000786 nucleosome(GO:0000786)
1.8 8.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.7 5.2 GO:0070557 PCNA-p21 complex(GO:0070557)
1.6 6.5 GO:0071942 XPC complex(GO:0071942)
1.6 4.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
1.6 23.9 GO:0042555 MCM complex(GO:0042555)
1.5 6.0 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.5 4.5 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.5 3.0 GO:0033061 DNA recombinase mediator complex(GO:0033061)
1.4 1.4 GO:0000811 GINS complex(GO:0000811)
1.4 12.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.3 5.3 GO:0032127 dense core granule membrane(GO:0032127)
1.3 10.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.3 3.8 GO:0005577 fibrinogen complex(GO:0005577)
1.2 5.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.2 4.8 GO:0043202 lysosomal lumen(GO:0043202)
1.2 28.7 GO:0005680 anaphase-promoting complex(GO:0005680)
1.2 17.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.1 16.1 GO:0005662 DNA replication factor A complex(GO:0005662)
1.1 13.7 GO:0042612 MHC class I protein complex(GO:0042612)
1.1 9.0 GO:0042382 paraspeckles(GO:0042382)
1.1 22.5 GO:0045120 pronucleus(GO:0045120)
1.1 8.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.0 5.1 GO:0032389 MutLalpha complex(GO:0032389)
1.0 7.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.0 4.1 GO:0036449 microtubule minus-end(GO:0036449)
1.0 6.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.0 5.0 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 10.0 GO:0031080 nuclear pore outer ring(GO:0031080)
1.0 6.0 GO:0034448 EGO complex(GO:0034448)
0.9 13.7 GO:0031011 Ino80 complex(GO:0031011)
0.9 12.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.9 4.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.9 6.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.9 0.9 GO:1903349 omegasome membrane(GO:1903349)
0.9 2.6 GO:0035061 interchromatin granule(GO:0035061)
0.9 43.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8 6.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.8 7.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.8 10.6 GO:0030061 mitochondrial crista(GO:0030061)
0.8 5.7 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.8 5.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.8 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.8 2.3 GO:1990423 RZZ complex(GO:1990423)
0.8 4.6 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.8 10.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.8 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.7 17.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.7 10.9 GO:0010369 chromocenter(GO:0010369)
0.7 7.9 GO:0005688 U6 snRNP(GO:0005688)
0.7 8.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.7 3.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7 7.1 GO:0045298 tubulin complex(GO:0045298)
0.7 3.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 2.7 GO:0043293 apoptosome(GO:0043293)
0.7 5.4 GO:0005787 signal peptidase complex(GO:0005787)
0.7 3.4 GO:0031298 replication fork protection complex(GO:0031298)
0.7 6.0 GO:0034709 methylosome(GO:0034709)
0.6 5.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.6 2.4 GO:0045098 type III intermediate filament(GO:0045098)
0.6 1.7 GO:0071914 prominosome(GO:0071914)
0.6 27.0 GO:0005657 replication fork(GO:0005657)
0.6 2.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.6 3.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 1.7 GO:0034457 Mpp10 complex(GO:0034457)
0.6 0.6 GO:0061574 ASAP complex(GO:0061574)
0.6 3.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.6 62.6 GO:0000776 kinetochore(GO:0000776)
0.5 6.5 GO:0016580 Sin3 complex(GO:0016580)
0.5 6.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.5 2.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.5 1.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.5 1.6 GO:0034657 GID complex(GO:0034657)
0.5 4.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.5 2.6 GO:1990037 Lewy body core(GO:1990037)
0.5 2.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.5 4.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.5 2.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.5 6.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 1.9 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.5 1.9 GO:0097447 dendritic tree(GO:0097447)
0.5 8.5 GO:0005682 U5 snRNP(GO:0005682)
0.5 5.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.5 2.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 3.2 GO:0072687 meiotic spindle(GO:0072687)
0.5 1.8 GO:0030870 Mre11 complex(GO:0030870)
0.4 0.4 GO:0001739 sex chromatin(GO:0001739)
0.4 12.9 GO:0005876 spindle microtubule(GO:0005876)
0.4 28.6 GO:0005643 nuclear pore(GO:0005643)
0.4 2.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.4 9.7 GO:0051233 spindle midzone(GO:0051233)
0.4 8.8 GO:0000242 pericentriolar material(GO:0000242)
0.4 4.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.4 1.7 GO:0070187 telosome(GO:0070187)
0.4 7.8 GO:0000346 transcription export complex(GO:0000346)
0.4 4.7 GO:0016589 NURF complex(GO:0016589)
0.4 3.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.4 1.5 GO:0032300 mismatch repair complex(GO:0032300)
0.4 2.3 GO:0097452 GAIT complex(GO:0097452)
0.4 1.5 GO:0033269 internode region of axon(GO:0033269)
0.4 3.3 GO:0043219 lateral loop(GO:0043219)
0.4 8.0 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.4 0.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 4.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 5.0 GO:0030008 TRAPP complex(GO:0030008)
0.3 2.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 0.3 GO:0070552 BRISC complex(GO:0070552)
0.3 4.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 3.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.3 2.0 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.3 3.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 1.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.6 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.3 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 2.8 GO:0061617 MICOS complex(GO:0061617)
0.3 29.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 1.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 4.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 1.1 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.3 2.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 3.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 1.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 21.0 GO:0005814 centriole(GO:0005814)
0.3 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 10.3 GO:0016592 mediator complex(GO:0016592)
0.3 1.6 GO:0030914 STAGA complex(GO:0030914)
0.3 3.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 3.3 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 5.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 0.7 GO:1990597 TRAF2-GSTP1 complex(GO:0097057) AIP1-IRE1 complex(GO:1990597)
0.2 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 9.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 2.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.9 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.5 GO:0031415 NatA complex(GO:0031415)
0.2 1.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 2.5 GO:0031209 SCAR complex(GO:0031209)
0.2 61.5 GO:0016607 nuclear speck(GO:0016607)
0.2 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 58.8 GO:0000790 nuclear chromatin(GO:0000790)
0.2 1.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.2 GO:0031021 equatorial microtubule organizing center(GO:0000923) gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) interphase microtubule organizing center(GO:0031021)
0.2 10.0 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.2 2.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 4.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 2.5 GO:0005839 proteasome core complex(GO:0005839)
0.2 7.8 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 11.7 GO:0005844 polysome(GO:0005844)
0.2 10.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 2.3 GO:0045180 basal cortex(GO:0045180)
0.2 1.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 2.4 GO:0031932 TORC2 complex(GO:0031932)
0.2 7.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 20.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.2 2.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 18.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 7.9 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 0.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.2 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 0.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 7.1 GO:0016459 myosin complex(GO:0016459)
0.2 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 4.3 GO:0000922 spindle pole(GO:0000922)
0.1 12.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.4 GO:0071564 npBAF complex(GO:0071564)
0.1 1.7 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.1 1.9 GO:0036038 MKS complex(GO:0036038)
0.1 1.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 11.7 GO:0005604 basement membrane(GO:0005604)
0.1 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 7.2 GO:0016605 PML body(GO:0016605)
0.1 0.4 GO:0001741 XY body(GO:0001741)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 10.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 10.8 GO:0030496 midbody(GO:0030496)
0.1 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 2.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.7 GO:1904949 ATPase complex(GO:1904949)
0.1 3.8 GO:0070469 respiratory chain(GO:0070469)
0.1 5.4 GO:0016234 inclusion body(GO:0016234)
0.1 5.0 GO:0031985 Golgi cisterna(GO:0031985)
0.1 4.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 9.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 2.0 GO:0005921 gap junction(GO:0005921)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 18.1 GO:0005635 nuclear envelope(GO:0005635)
0.1 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 2.6 GO:0031519 PcG protein complex(GO:0031519)
0.1 4.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.4 GO:0030286 dynein complex(GO:0030286)
0.1 2.0 GO:0097546 ciliary base(GO:0097546)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0005912 adherens junction(GO:0005912)
0.1 1.5 GO:0030904 retromer complex(GO:0030904)
0.1 8.0 GO:0005681 spliceosomal complex(GO:0005681)
0.1 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 0.1 GO:0044301 climbing fiber(GO:0044301)
0.1 1.4 GO:0005795 Golgi stack(GO:0005795)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0045178 basal part of cell(GO:0045178)
0.1 0.4 GO:0042587 glycogen granule(GO:0042587)
0.1 13.5 GO:0005925 focal adhesion(GO:0005925)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 51.5 GO:0005615 extracellular space(GO:0005615)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 36.9 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 67.7 GO:0005634 nucleus(GO:0005634)
0.0 0.8 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 32.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
7.8 23.4 GO:0035939 microsatellite binding(GO:0035939)
4.3 17.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
3.6 18.1 GO:0035174 histone serine kinase activity(GO:0035174)
2.9 14.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
2.6 5.2 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
2.5 7.6 GO:0032137 guanine/thymine mispair binding(GO:0032137)
2.5 10.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
2.5 10.0 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
2.5 121.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
2.5 14.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
2.4 14.2 GO:0050786 RAGE receptor binding(GO:0050786)
2.3 9.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.3 9.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.1 22.8 GO:0008430 selenium binding(GO:0008430)
2.0 2.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.0 6.0 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
2.0 5.9 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
1.9 13.5 GO:0070888 E-box binding(GO:0070888)
1.9 5.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.9 5.6 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.8 8.9 GO:0043515 kinetochore binding(GO:0043515)
1.7 18.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
1.7 6.7 GO:0036435 deubiquitinase activator activity(GO:0035800) K48-linked polyubiquitin binding(GO:0036435)
1.7 5.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.7 23.3 GO:0003688 DNA replication origin binding(GO:0003688)
1.6 6.5 GO:0048408 epidermal growth factor binding(GO:0048408)
1.5 16.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
1.5 1.5 GO:0015616 DNA translocase activity(GO:0015616)
1.5 13.2 GO:0035173 histone kinase activity(GO:0035173)
1.5 5.9 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
1.4 11.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.4 4.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.4 5.6 GO:0032357 oxidized purine DNA binding(GO:0032357)
1.4 5.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.4 8.3 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
1.4 4.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
1.3 4.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.3 17.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.3 9.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.3 2.6 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
1.3 22.9 GO:0000400 four-way junction DNA binding(GO:0000400)
1.3 6.4 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.3 5.1 GO:0008142 oxysterol binding(GO:0008142)
1.2 11.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
1.2 6.1 GO:0004594 pantothenate kinase activity(GO:0004594)
1.2 4.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.2 11.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.2 7.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
1.2 4.7 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
1.1 2.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.1 2.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
1.1 8.8 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
1.1 3.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.1 4.2 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.0 3.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
1.0 8.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.0 1.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.0 10.1 GO:0015266 protein channel activity(GO:0015266)
1.0 6.0 GO:0070728 leucine binding(GO:0070728)
1.0 5.9 GO:0042731 PH domain binding(GO:0042731)
0.9 6.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.9 28.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.9 3.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.9 4.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.9 2.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.9 2.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.9 3.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.9 3.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.9 3.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 3.5 GO:0004111 creatine kinase activity(GO:0004111)
0.9 6.1 GO:0015925 galactosidase activity(GO:0015925)
0.9 0.9 GO:0008502 melatonin receptor activity(GO:0008502)
0.9 1.7 GO:0009881 photoreceptor activity(GO:0009881)
0.9 6.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 6.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.9 2.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.8 14.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.8 5.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.8 7.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.8 2.4 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
0.8 3.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.8 4.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.8 11.6 GO:0046977 TAP binding(GO:0046977)
0.8 6.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 3.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.7 17.1 GO:0097602 cullin family protein binding(GO:0097602)
0.7 7.4 GO:0036310 annealing helicase activity(GO:0036310)
0.7 11.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 2.2 GO:0030519 snoRNP binding(GO:0030519)
0.7 6.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.7 9.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.7 4.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.7 2.7 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.7 6.1 GO:0030274 LIM domain binding(GO:0030274)
0.7 2.7 GO:0047134 phosphotransferase activity, carboxyl group as acceptor(GO:0016774) protein-disulfide reductase activity(GO:0047134)
0.7 4.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.7 15.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.7 2.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.7 18.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.7 4.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 1.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.7 2.6 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.6 3.9 GO:0045340 mercury ion binding(GO:0045340)
0.6 9.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.6 5.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 7.5 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.6 2.5 GO:0044020 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.6 2.4 GO:1990254 keratin filament binding(GO:1990254)
0.6 5.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.6 12.0 GO:0008483 transaminase activity(GO:0008483)
0.6 1.8 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.6 8.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 5.8 GO:0050733 RS domain binding(GO:0050733)
0.6 1.8 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.6 2.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.6 1.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.6 2.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.6 1.7 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.6 8.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 56.0 GO:0051082 unfolded protein binding(GO:0051082)
0.6 3.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 2.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.5 7.1 GO:0003680 AT DNA binding(GO:0003680)
0.5 7.4 GO:0042605 peptide antigen binding(GO:0042605)
0.5 2.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5 2.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.5 16.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 1.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.5 6.7 GO:0031386 protein tag(GO:0031386)
0.5 2.1 GO:0030984 kininogen binding(GO:0030984)
0.5 2.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.5 5.1 GO:0035198 miRNA binding(GO:0035198)
0.5 23.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.5 5.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.5 2.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.5 8.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.5 1.9 GO:0050700 CARD domain binding(GO:0050700)
0.5 2.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 0.5 GO:0003681 bent DNA binding(GO:0003681)
0.5 5.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.5 1.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.5 1.4 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.5 2.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.5 3.2 GO:0042301 phosphate ion binding(GO:0042301)
0.5 3.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 1.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 6.7 GO:0017166 vinculin binding(GO:0017166)
0.4 3.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.4 1.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 4.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.4 1.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.4 0.9 GO:0005119 smoothened binding(GO:0005119)
0.4 1.7 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.4 3.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.4 1.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 1.7 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.4 1.3 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.4 2.6 GO:0008301 DNA binding, bending(GO:0008301)
0.4 27.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 0.8 GO:0005113 patched binding(GO:0005113)
0.4 2.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 2.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 4.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.4 1.2 GO:0004454 ketohexokinase activity(GO:0004454)
0.4 4.1 GO:0070990 snRNP binding(GO:0070990)
0.4 4.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 2.4 GO:0097016 L27 domain binding(GO:0097016)
0.4 0.8 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.4 1.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.4 3.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 28.4 GO:0051087 chaperone binding(GO:0051087)
0.4 2.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 4.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 1.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 1.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.4 2.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 1.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 1.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.4 1.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.4 34.8 GO:0035326 enhancer binding(GO:0035326)
0.4 3.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.4 0.4 GO:0001851 complement component C3b binding(GO:0001851)
0.4 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 2.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 1.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.4 4.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 8.0 GO:0017091 AU-rich element binding(GO:0017091)
0.3 6.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 1.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 22.5 GO:0003777 microtubule motor activity(GO:0003777)
0.3 2.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 1.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.3 20.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 1.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 1.0 GO:0033142 progesterone receptor binding(GO:0033142)
0.3 1.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 2.8 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.3 5.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 1.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.5 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3 1.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3 1.5 GO:0070404 NADH binding(GO:0070404)
0.3 0.6 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.3 0.9 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 2.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.3 2.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 4.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 41.3 GO:0001047 core promoter binding(GO:0001047)
0.3 2.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.3 5.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 5.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 9.9 GO:0050699 WW domain binding(GO:0050699)
0.3 1.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.1 GO:0048039 ubiquinone binding(GO:0048039)
0.3 1.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 2.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 1.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 2.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 6.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 4.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 2.1 GO:0005537 mannose binding(GO:0005537)
0.3 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 1.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 4.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 4.3 GO:0015026 coreceptor activity(GO:0015026)
0.3 2.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.3 7.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 3.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 3.9 GO:0016594 glycine binding(GO:0016594)
0.2 5.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 8.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 1.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 4.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 0.7 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.2 1.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.7 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 2.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 3.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 10.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 2.9 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 0.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.2 2.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 4.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.2 10.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 0.6 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.2 6.9 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.2 1.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 3.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 1.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 2.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 3.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 4.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 12.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 0.7 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 0.5 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.2 1.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 10.4 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.9 GO:1990188 euchromatin binding(GO:1990188)
0.2 3.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.2 1.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.8 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 2.9 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 0.3 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.2 24.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.6 GO:0005534 galactose binding(GO:0005534)
0.2 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 2.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 3.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 3.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.9 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 4.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 3.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 4.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 2.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 6.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 15.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 10.6 GO:0008083 growth factor activity(GO:0008083)
0.1 0.5 GO:0019808 polyamine binding(GO:0019808)
0.1 0.3 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 5.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 3.4 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.9 GO:0010181 FMN binding(GO:0010181)
0.1 23.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 23.6 GO:0008017 microtubule binding(GO:0008017)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 9.2 GO:0005506 iron ion binding(GO:0005506)
0.1 1.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 3.7 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 4.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 16.3 GO:0042393 histone binding(GO:0042393)
0.1 3.3 GO:0009055 electron carrier activity(GO:0009055)
0.1 5.1 GO:0003774 motor activity(GO:0003774)
0.1 8.0 GO:0004386 helicase activity(GO:0004386)
0.1 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 2.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.1 1.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.9 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 4.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.5 GO:0016151 nickel cation binding(GO:0016151)
0.1 19.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 1.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.5 GO:0004527 exonuclease activity(GO:0004527)
0.1 2.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 23.3 GO:0045296 cadherin binding(GO:0045296)
0.1 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 5.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.7 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 8.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 3.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 2.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 2.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 1.0 GO:0017069 snRNA binding(GO:0017069)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.2 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 2.3 GO:0005179 hormone activity(GO:0005179)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.7 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.2 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.2 GO:0043176 amine binding(GO:0043176)
0.0 3.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.4 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 1.6 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) chloride ion binding(GO:0031404) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0015093 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.6 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0030145 manganese ion binding(GO:0030145)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 138.2 PID_PLK1_PATHWAY PLK1 signaling events
2.0 28.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.5 55.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
1.1 51.9 PID_FANCONI_PATHWAY Fanconi anemia pathway
1.1 30.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.9 32.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.7 40.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.7 14.4 PID_ATR_PATHWAY ATR signaling pathway
0.6 1.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.6 6.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.6 6.8 PID_BARD1_PATHWAY BARD1 signaling events
0.6 14.5 PID_MYC_PATHWAY C-MYC pathway
0.6 13.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.5 17.6 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.5 6.4 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.5 34.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.5 20.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.5 10.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.4 11.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 39.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.4 11.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.4 13.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.4 11.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.3 15.0 PID_E2F_PATHWAY E2F transcription factor network
0.3 2.7 PID_ATM_PATHWAY ATM pathway
0.3 24.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.3 2.6 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 19.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.3 11.7 PID_IL12_2PATHWAY IL12-mediated signaling events
0.3 4.6 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.2 5.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 2.9 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 3.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.2 6.0 PID_FOXO_PATHWAY FoxO family signaling
0.2 10.3 PID_CDC42_PATHWAY CDC42 signaling events
0.2 6.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 1.3 PID_EPO_PATHWAY EPO signaling pathway
0.2 9.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 1.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.2 10.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.2 2.0 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.2 8.0 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 1.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.2 2.3 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.2 2.0 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.2 5.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 3.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 11.4 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.2 7.8 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 0.6 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 2.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.8 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 4.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 1.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.4 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 4.8 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 2.3 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 5.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 5.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 2.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 1.1 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.7 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.0 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 0.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.7 PID_BMP_PATHWAY BMP receptor signaling
0.1 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 1.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.6 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 0.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 1.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 7.4 REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
3.0 6.1 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
2.8 47.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
2.7 43.2 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
2.5 22.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.5 130.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
2.3 34.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
1.9 31.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.8 44.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.7 43.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.7 16.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.6 34.8 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
1.4 19.9 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.3 9.0 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
1.3 3.8 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.1 29.7 REACTOME_KINESINS Genes involved in Kinesins
1.1 13.8 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.0 12.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.9 76.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.8 10.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.8 9.0 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.8 14.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.8 9.4 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.8 22.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.8 4.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.8 4.5 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8 1.5 REACTOME_DNA_REPLICATION Genes involved in DNA Replication
0.7 23.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.7 8.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.6 5.1 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 9.6 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.5 0.5 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5 2.7 REACTOME_G2_M_CHECKPOINTS Genes involved in G2/M Checkpoints
0.5 6.3 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.5 34.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.5 6.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5 1.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.5 23.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.5 4.0 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 8.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 10.5 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5 8.0 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.5 2.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 9.4 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.5 12.0 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 58.1 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.4 15.1 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.4 5.8 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 19.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.4 1.3 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.4 22.8 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.4 6.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.4 5.9 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 5.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.4 7.4 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.4 4.5 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.4 4.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 8.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.4 6.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.4 3.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 4.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.4 3.8 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 5.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.4 13.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 17.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 2.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 1.7 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 1.7 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 1.7 REACTOME_TELOMERE_MAINTENANCE Genes involved in Telomere Maintenance
0.3 6.9 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.3 4.6 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 2.6 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.3 7.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 1.1 REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.3 13.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 1.8 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3 18.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 6.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.2 3.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.9 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 3.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 4.8 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2 13.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 3.7 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 5.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 16.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 14.3 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 0.8 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.2 3.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE Genes involved in Acyl chain remodelling of PE
0.2 2.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.2 2.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.2 8.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 4.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 0.7 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 2.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 4.0 REACTOME_TRANSLATION Genes involved in Translation
0.2 1.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 7.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 5.2 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.1 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 10.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 10.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.3 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.8 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.8 REACTOME_SIGNALLING_TO_RAS Genes involved in Signalling to RAS
0.1 1.9 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 8.6 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 1.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.7 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.8 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.6 REACTOME_METABOLISM_OF_NUCLEOTIDES Genes involved in Metabolism of nucleotides
0.1 2.1 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.8 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 0.7 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 0.3 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.2 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.1 REACTOME_PROTEIN_FOLDING Genes involved in Protein folding
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.1 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway