Motif ID: Hand1

Z-value: 1.002


Transcription factors associated with Hand1:

Gene SymbolEntrez IDGene Name
Hand1 ENSMUSG00000037335.7 Hand1



Activity profile for motif Hand1.

activity profile for motif Hand1


Sorted Z-values histogram for motif Hand1

Sorted Z-values for motif Hand1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hand1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_59076069 2.889 ENSMUST00000047511.7
ENSMUST00000163821.1
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr15_+_92051153 2.444 ENSMUST00000169825.1
Cntn1
contactin 1
chr15_+_81936911 2.381 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr19_-_5796924 2.256 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr19_-_5797410 2.187 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr1_+_75507077 2.184 ENSMUST00000037330.4
Inha
inhibin alpha
chr4_-_138396438 1.997 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr7_-_30445508 1.957 ENSMUST00000006828.7
Aplp1
amyloid beta (A4) precursor-like protein 1
chr15_+_80097866 1.939 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr19_-_4698315 1.935 ENSMUST00000096325.3
Gm960
predicted gene 960
chr17_-_81649607 1.769 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr10_+_58255465 1.678 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
Gcc2


GRIP and coiled-coil domain containing 2


chr1_-_37865040 1.678 ENSMUST00000041815.8
Tsga10
testis specific 10
chr15_+_81936753 1.534 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr2_+_118663235 1.532 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_+_27622433 1.531 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr5_+_75152274 1.523 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_84723003 1.519 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr17_+_3532554 1.417 ENSMUST00000168560.1
Cldn20
claudin 20
chr1_-_176807124 1.408 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr10_-_29144194 1.379 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr4_-_20778527 1.337 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr13_+_29014399 1.310 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr13_-_92131494 1.308 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr9_-_20879718 1.295 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr4_-_141598206 1.293 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr12_+_73997749 1.286 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr19_+_4855129 1.257 ENSMUST00000119694.1
Ctsf
cathepsin F
chr11_+_101246960 1.250 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr11_+_57011945 1.246 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_78188737 1.227 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr15_-_58214882 1.225 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr15_-_71727815 1.212 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr11_-_81968415 1.211 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr9_-_122862128 1.181 ENSMUST00000056467.7
Zfp445
zinc finger protein 445
chr17_+_21491256 1.165 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr11_+_3330781 1.148 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr11_+_57011798 1.134 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr19_-_4698668 1.124 ENSMUST00000177696.1
Gm960
predicted gene 960
chr10_+_29143996 1.117 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr3_+_86084434 1.108 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr5_+_19907502 1.100 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_66968559 1.100 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr3_+_96576984 1.095 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr4_+_102760294 1.071 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr16_+_38089001 1.062 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr5_+_81021202 1.061 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr15_+_82274935 1.040 ENSMUST00000023095.6
Sept3
septin 3
chr5_+_19907774 1.040 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_+_82138253 1.032 ENSMUST00000105314.2
AU041133
expressed sequence AU041133
chr4_-_45084538 1.029 ENSMUST00000052236.6
Fbxo10
F-box protein 10
chr14_-_26971232 1.026 ENSMUST00000036570.4
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr11_+_70459940 1.023 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr6_-_41636389 1.023 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr11_-_60115226 1.014 ENSMUST00000130746.1
4930412M03Rik
RIKEN cDNA 4930412M03 gene
chr11_-_106613370 0.986 ENSMUST00000128933.1
Tex2
testis expressed gene 2
chr13_-_21531032 0.983 ENSMUST00000156674.2
ENSMUST00000110481.2
Zkscan8

zinc finger with KRAB and SCAN domains 8

chr2_-_150451486 0.980 ENSMUST00000109916.1
Zfp442
zinc finger protein 442
chr9_-_101251810 0.977 ENSMUST00000075941.5
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr9_-_50739365 0.967 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr1_-_170110491 0.966 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr5_+_66968961 0.954 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr4_+_102760135 0.954 ENSMUST00000066824.7
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr19_+_11469353 0.949 ENSMUST00000165310.1
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr19_-_42086338 0.923 ENSMUST00000051772.8
Morn4
MORN repeat containing 4
chr2_-_168741752 0.921 ENSMUST00000029060.4
Atp9a
ATPase, class II, type 9A
chrX_-_95166307 0.920 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
Arhgef9







CDC42 guanine nucleotide exchange factor (GEF) 9







chr16_-_16599978 0.907 ENSMUST00000162671.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr1_-_79761752 0.903 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
Wdfy1






WD repeat and FYVE domain containing 1






chr4_-_151108454 0.898 ENSMUST00000105670.1
Camta1
calmodulin binding transcription activator 1
chr12_+_112588753 0.877 ENSMUST00000101029.2
Inf2
inverted formin, FH2 and WH2 domain containing
chr18_+_37484955 0.873 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr12_-_72070991 0.851 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr17_-_13131791 0.845 ENSMUST00000084966.5
Unc93a
unc-93 homolog A (C. elegans)
chr13_-_21531084 0.837 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr18_+_37400845 0.834 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr11_+_78188422 0.829 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chr13_-_34077992 0.826 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr11_-_42000284 0.823 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr12_+_65075582 0.818 ENSMUST00000058889.4
Fancm
Fanconi anemia, complementation group M
chr4_-_20778852 0.815 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr1_+_136624901 0.815 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr18_+_37435602 0.805 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr5_+_138171997 0.797 ENSMUST00000019662.4
ENSMUST00000151318.1
Ap4m1

adaptor-related protein complex AP-4, mu 1

chr7_-_79131018 0.796 ENSMUST00000032827.7
Hapln3
hyaluronan and proteoglycan link protein 3
chr4_+_126609818 0.789 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr4_-_148500449 0.782 ENSMUST00000030840.3
Angptl7
angiopoietin-like 7
chr15_-_81697256 0.780 ENSMUST00000072910.5
Chadl
chondroadherin-like
chrX_+_153237466 0.773 ENSMUST00000143880.1
Klf8
Kruppel-like factor 8
chr11_-_109298090 0.772 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr3_+_107101551 0.770 ENSMUST00000038695.1
Kcna2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr16_+_4036942 0.764 ENSMUST00000137748.1
ENSMUST00000006136.4
ENSMUST00000157044.1
ENSMUST00000120009.1
Dnase1



deoxyribonuclease I



chr7_+_28693032 0.762 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr5_+_66968416 0.754 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr5_-_84417359 0.751 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr5_-_38220400 0.749 ENSMUST00000114113.1
ENSMUST00000094833.3
Zbtb49

zinc finger and BTB domain containing 49

chr10_-_118868903 0.742 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr7_-_47133395 0.740 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr11_-_102296618 0.736 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr2_-_173276144 0.735 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr4_-_127313980 0.721 ENSMUST00000053753.7
Gja4
gap junction protein, alpha 4
chr7_-_47133684 0.721 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr1_+_165788746 0.714 ENSMUST00000161559.2
Cd247
CD247 antigen
chr11_-_96916366 0.710 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr4_-_118179946 0.705 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr7_+_126950518 0.703 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr12_-_40134175 0.703 ENSMUST00000078481.7
ENSMUST00000002640.5
Scin

scinderin

chr4_-_118180043 0.697 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr8_+_20567716 0.689 ENSMUST00000178995.1
Gm21092
predicted gene, 21092
chr7_-_27553138 0.685 ENSMUST00000127240.1
ENSMUST00000117095.1
ENSMUST00000117611.1
Pld3


phospholipase D family, member 3


chr1_+_165788681 0.684 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr15_+_82275197 0.684 ENSMUST00000116423.1
Sept3
septin 3
chr7_-_19604444 0.680 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr7_-_19310035 0.674 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr5_-_71658308 0.672 ENSMUST00000031121.5
Gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr1_-_135167606 0.670 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr11_+_78188806 0.666 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chr3_+_36159522 0.663 ENSMUST00000165956.2
D3Ertd254e
DNA segment, Chr 3, ERATO Doi 254, expressed
chr11_+_4135233 0.659 ENSMUST00000124670.1
Rnf215
ring finger protein 215
chr3_+_65109343 0.657 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr11_+_32000496 0.638 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr7_+_126950687 0.633 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr17_+_27018005 0.632 ENSMUST00000122106.1
Ggnbp1
gametogenetin binding protein 1
chr13_+_37345338 0.620 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr4_-_42034726 0.619 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr18_+_24709436 0.619 ENSMUST00000037097.7
Fhod3
formin homology 2 domain containing 3
chr17_-_45686899 0.614 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr16_-_34095983 0.614 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr7_+_141061274 0.611 ENSMUST00000048002.5
B4galnt4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr18_-_31317043 0.602 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr5_-_108132513 0.596 ENSMUST00000119784.1
ENSMUST00000117759.1
Tmed5

transmembrane emp24 protein transport domain containing 5

chr2_+_175010241 0.590 ENSMUST00000109069.1
ENSMUST00000109070.2
Gm14444

predicted gene 14444

chr16_-_36784924 0.590 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr5_+_108132885 0.590 ENSMUST00000047677.7
Ccdc18
coiled-coil domain containing 18
chr14_-_118925314 0.582 ENSMUST00000004055.8
Dzip1
DAZ interacting protein 1
chr19_-_42202150 0.574 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr4_-_118179628 0.568 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr2_+_96318014 0.564 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr12_+_119945957 0.554 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr5_-_108132541 0.554 ENSMUST00000119437.1
ENSMUST00000118036.1
Tmed5

transmembrane emp24 protein transport domain containing 5

chr7_-_45366714 0.553 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr13_-_117025505 0.552 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr10_+_60399726 0.552 ENSMUST00000164428.1
Gm17455
predicted gene, 17455
chr5_+_71699918 0.549 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr7_+_47050628 0.539 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr10_-_127041513 0.532 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr2_+_119174483 0.531 ENSMUST00000069711.2
Gm14137
predicted gene 14137
chr17_-_47692466 0.528 ENSMUST00000113300.1
Prickle4
prickle homolog 4 (Drosophila)
chrX_+_109095359 0.521 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr4_-_155653184 0.519 ENSMUST00000030937.1
Mmp23
matrix metallopeptidase 23
chrX_-_153696195 0.518 ENSMUST00000039424.8
ENSMUST00000112572.1
Kctd12b

potassium channel tetramerisation domain containing 12b

chr2_+_85136355 0.518 ENSMUST00000057019.7
Aplnr
apelin receptor
chr4_+_136357423 0.516 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr14_+_51893610 0.514 ENSMUST00000047726.5
ENSMUST00000161888.1
Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr1_-_39478734 0.507 ENSMUST00000054462.5
Tbc1d8
TBC1 domain family, member 8
chr16_+_31422268 0.507 ENSMUST00000089759.2
Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr6_+_17491216 0.504 ENSMUST00000080469.5
Met
met proto-oncogene
chr2_+_178141920 0.502 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr19_-_5845471 0.502 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr11_-_106612928 0.498 ENSMUST00000042780.7
Tex2
testis expressed gene 2
chr15_+_98092569 0.496 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chr2_+_149830840 0.493 ENSMUST00000109934.1
ENSMUST00000140870.1
Syndig1

synapse differentiation inducing 1

chr2_+_149830894 0.493 ENSMUST00000137280.1
ENSMUST00000149705.1
Syndig1

synapse differentiation inducing 1

chr15_+_60822947 0.480 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr2_-_27027909 0.478 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chr5_-_75978447 0.470 ENSMUST00000113516.1
Kdr
kinase insert domain protein receptor
chr10_-_62880014 0.470 ENSMUST00000050826.7
Tet1
tet methylcytosine dioxygenase 1
chr6_+_127453667 0.462 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr12_-_76822510 0.459 ENSMUST00000021459.7
Rab15
RAB15, member RAS oncogene family
chr2_+_154551771 0.456 ENSMUST00000104928.1
Actl10
actin-like 10
chr16_-_16600533 0.450 ENSMUST00000159542.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chrX_+_10485121 0.447 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr7_+_81523555 0.447 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr12_+_105453831 0.444 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chr8_+_93810832 0.443 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr4_-_117883428 0.442 ENSMUST00000030266.5
B4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr11_-_95041335 0.437 ENSMUST00000038431.7
Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
chr4_+_43632185 0.437 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr5_-_108132577 0.431 ENSMUST00000061203.6
ENSMUST00000002837.4
Tmed5

transmembrane emp24 protein transport domain containing 5

chr9_+_58823512 0.429 ENSMUST00000034889.8
Hcn4
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
chr6_-_85762480 0.427 ENSMUST00000168531.1
Cml3
camello-like 3
chr3_+_88685785 0.426 ENSMUST00000029696.6
2810403A07Rik
RIKEN cDNA 2810403A07 gene
chr15_+_81400132 0.422 ENSMUST00000163754.1
ENSMUST00000041609.4
Xpnpep3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr2_+_79255500 0.422 ENSMUST00000099972.4
Itga4
integrin alpha 4
chr7_-_98112618 0.419 ENSMUST00000153657.1
Myo7a
myosin VIIA
chr5_-_52669677 0.414 ENSMUST00000031069.6
Sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr13_-_41847626 0.413 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr2_+_37443273 0.413 ENSMUST00000133434.1
ENSMUST00000061179.5
Rabgap1

RAB GTPase activating protein 1

chr11_-_109298121 0.406 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr19_-_4163285 0.393 ENSMUST00000118483.1
ENSMUST00000025749.7
Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

chr7_+_81858993 0.385 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr9_+_88839164 0.384 ENSMUST00000163255.2
Trim43c
tripartite motif-containing 43C
chr7_-_134232005 0.383 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr15_-_37458523 0.382 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr2_+_30392405 0.379 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr15_+_78428564 0.373 ENSMUST00000166142.2
ENSMUST00000162517.1
ENSMUST00000089414.4
Kctd17


potassium channel tetramerisation domain containing 17


chr2_+_110597298 0.372 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr1_+_93235836 0.371 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr18_+_77938452 0.371 ENSMUST00000044622.5
Epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr4_-_129623870 0.364 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
Ccdc28b


coiled coil domain containing 28B



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0035063 nuclear speck organization(GO:0035063)
0.8 3.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.7 2.0 GO:0071873 response to norepinephrine(GO:0071873)
0.5 2.7 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.5 1.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.4 1.2 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4 1.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.4 2.2 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.4 1.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.4 1.8 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.3 1.0 GO:0007525 somatic muscle development(GO:0007525)
0.3 2.1 GO:2001023 regulation of response to drug(GO:2001023)
0.3 1.7 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.3 2.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 0.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.2 2.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.6 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 2.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 0.5 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 0.5 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.2 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 1.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 2.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.9 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.8 GO:0021631 optic nerve morphogenesis(GO:0021631) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.6 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.4 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 0.6 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.1 0.4 GO:1901608 regulation of vesicle transport along microtubule(GO:1901608)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:1904996 diapedesis(GO:0050904) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 1.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.5 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 0.3 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.9 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.1 0.7 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.6 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989) actin filament severing(GO:0051014)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 2.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 2.4 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 2.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117) NMDA glutamate receptor clustering(GO:0097114)
0.0 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.2 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.7 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.5 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.4 GO:0035881 amacrine cell differentiation(GO:0035881) retinal rod cell development(GO:0046548)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.3 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.9 GO:0043113 receptor clustering(GO:0043113)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 3.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 1.5 GO:0007613 memory(GO:0007613)
0.0 1.0 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.0 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.4 2.7 GO:0044308 axonal spine(GO:0044308)
0.4 1.7 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.3 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 2.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:0097447 dendritic tree(GO:0097447)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 2.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 2.1 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.1 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.5 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 2.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 3.5 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.5 2.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 1.8 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 2.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 2.4 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 1.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 2.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 2.2 GO:0034711 inhibin binding(GO:0034711)
0.2 1.2 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.6 GO:0042936 dipeptide transporter activity(GO:0042936)
0.2 0.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 2.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.3 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 1.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.0 GO:0030276 clathrin binding(GO:0030276)
0.0 2.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.5 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 2.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 0.9 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 1.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 3.0 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 1.1 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.0 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.9 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.8 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.2 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.4 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 1.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 3.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.1 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.0 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 0.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.9 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.2 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.4 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer