Motif ID: Hoxc6

Z-value: 0.301


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_73740277 0.908 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr5_+_17574268 0.739 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_22315792 0.713 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr11_-_26210553 0.686 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr4_+_144893127 0.634 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_+_65620829 0.511 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr19_+_32619997 0.418 ENSMUST00000025833.6
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr3_+_66985680 0.413 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr3_-_113574242 0.413 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chrX_-_143933089 0.390 ENSMUST00000087313.3
Dcx
doublecortin
chr3_+_5218589 0.387 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr3_+_5218516 0.368 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr19_+_26748268 0.365 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr19_+_11469353 0.362 ENSMUST00000165310.1
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr8_-_54724317 0.340 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr3_+_5218546 0.313 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chrX_-_143933204 0.283 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr16_-_21995478 0.270 ENSMUST00000074230.4
ENSMUST00000060673.6
Liph

lipase, member H

chr6_-_65144908 0.248 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chr10_-_100589205 0.225 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr10_-_70655934 0.212 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr18_+_37484955 0.207 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr1_-_189922338 0.193 ENSMUST00000027897.7
Smyd2
SET and MYND domain containing 2
chr11_-_109472611 0.191 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_+_123123870 0.186 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr7_-_19604444 0.172 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr3_+_151437887 0.172 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr8_-_54724474 0.172 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr10_-_53647080 0.116 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr7_-_24299310 0.114 ENSMUST00000145131.1
Zfp61
zinc finger protein 61
chr3_+_66985647 0.114 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr7_-_16285454 0.102 ENSMUST00000174270.1
Ccdc9
coiled-coil domain containing 9
chr8_-_9976294 0.098 ENSMUST00000095476.4
Lig4
ligase IV, DNA, ATP-dependent
chr10_+_61175206 0.096 ENSMUST00000079235.5
Tbata
thymus, brain and testes associated
chr6_+_128399766 0.091 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr1_-_43827751 0.083 ENSMUST00000128261.1
ENSMUST00000126008.1
ENSMUST00000139451.1
Uxs1


UDP-glucuronate decarboxylase 1


chr8_-_109962127 0.081 ENSMUST00000001722.7
ENSMUST00000051430.6
Marveld3

MARVEL (membrane-associating) domain containing 3

chr7_+_5020376 0.074 ENSMUST00000076251.4
Zfp865
zinc finger protein 865
chr3_+_136670076 0.071 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr17_-_78985428 0.068 ENSMUST00000118991.1
Prkd3
protein kinase D3
chr18_-_56572888 0.066 ENSMUST00000174518.1
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr13_+_93304066 0.048 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr5_-_23616528 0.047 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr13_+_93304799 0.032 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chrM_+_14138 0.031 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr17_-_35115428 0.030 ENSMUST00000172854.1
ENSMUST00000062657.4
Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr1_+_88103229 0.023 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr10_-_58718210 0.011 ENSMUST00000169859.1
Gm17542
predicted gene, 17542
chr7_-_34655500 0.009 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr1_+_88134786 0.006 ENSMUST00000113134.1
ENSMUST00000140092.1
Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr15_+_100154379 0.001 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.4 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules