Motif ID: Sox4

Z-value: 0.487


Transcription factors associated with Sox4:

Gene SymbolEntrez IDGene Name
Sox4 ENSMUSG00000076431.4 Sox4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox4mm10_v2_chr13_-_28953690_28953713-0.494.0e-02Click!


Activity profile for motif Sox4.

activity profile for motif Sox4


Sorted Z-values histogram for motif Sox4

Sorted Z-values for motif Sox4



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103853199 3.084 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr17_-_70851189 1.346 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chrX_+_73639414 1.195 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr7_+_45216671 1.191 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr3_+_131110350 1.099 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr9_+_85842852 0.999 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr18_-_62756275 0.853 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr12_-_54986363 0.785 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr13_+_117220584 0.779 ENSMUST00000022242.7
Emb
embigin
chr9_-_103480328 0.773 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr17_-_70853482 0.763 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr7_-_100514800 0.694 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr19_+_56874249 0.669 ENSMUST00000026068.7
Vwa2
von Willebrand factor A domain containing 2
chr11_+_88068242 0.589 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr1_+_153665274 0.583 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr5_+_115908644 0.576 ENSMUST00000141101.1
Cit
citron
chr5_+_75075464 0.571 ENSMUST00000160104.1
ENSMUST00000040477.3
Gsx2

GS homeobox 2

chr3_+_146500071 0.564 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr7_+_100493795 0.545 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_+_102296256 0.532 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr17_-_35704000 0.525 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr7_+_127233044 0.525 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr12_+_24708984 0.504 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr14_+_27039001 0.486 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr7_-_105752193 0.483 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr7_+_127233227 0.463 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr12_-_54986328 0.456 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr11_-_115813621 0.454 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr6_-_39557830 0.444 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr18_-_15063560 0.438 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr11_-_98625661 0.387 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr10_+_80150448 0.383 ENSMUST00000153477.1
Midn
midnolin
chr17_-_35704574 0.382 ENSMUST00000117301.1
ENSMUST00000134995.1
Ddr1

discoidin domain receptor family, member 1

chr4_+_41762309 0.368 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr7_+_100494044 0.356 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr14_+_64589802 0.337 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr19_+_40831248 0.337 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chrX_+_71556874 0.337 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr17_+_75005523 0.335 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr17_-_35697971 0.333 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr6_-_47813512 0.329 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr7_-_105787544 0.310 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr6_-_38875965 0.299 ENSMUST00000160360.1
Hipk2
homeodomain interacting protein kinase 2
chr10_+_80151154 0.296 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr9_+_13765970 0.284 ENSMUST00000152532.1
Mtmr2
myotubularin related protein 2
chrX_-_145505136 0.277 ENSMUST00000112835.1
Amot
angiomotin
chr2_+_78869009 0.268 ENSMUST00000028398.7
Ube2e3
ubiquitin-conjugating enzyme E2E 3
chrX_-_10117597 0.267 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
Srpx


sushi-repeat-containing protein


chr9_+_104002546 0.263 ENSMUST00000035167.8
ENSMUST00000117054.1
Nphp3

nephronophthisis 3 (adolescent)

chr9_-_32541589 0.261 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr4_+_115057683 0.254 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr1_+_59482133 0.250 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr8_+_108714644 0.231 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr12_-_24252181 0.224 ENSMUST00000169148.1
Gm9312
predicted gene 9312
chr7_-_105787567 0.220 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr11_+_101442440 0.213 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr19_+_34922351 0.212 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr16_-_84835557 0.205 ENSMUST00000138279.1
ENSMUST00000023608.7
Atp5j

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

chr5_+_44100442 0.203 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr11_-_106160101 0.203 ENSMUST00000045923.3
Limd2
LIM domain containing 2
chr14_+_47298260 0.199 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr15_-_79254737 0.194 ENSMUST00000039752.3
Slc16a8
solute carrier family 16 (monocarboxylic acid transporters), member 8
chr3_-_95882031 0.194 ENSMUST00000161994.1
Gm129
predicted gene 129
chr11_-_100650693 0.192 ENSMUST00000103119.3
Zfp385c
zinc finger protein 385C
chr15_-_44428303 0.184 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr2_-_101649501 0.183 ENSMUST00000160722.1
ENSMUST00000160037.1
ENSMUST00000078494.5
B230118H07Rik

Rag1
RIKEN cDNA B230118H07 gene

recombination activating gene 1
chr11_+_101442298 0.174 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr3_+_89164790 0.173 ENSMUST00000121212.2
ENSMUST00000152205.1
ENSMUST00000090927.5
ENSMUST00000148265.1
ENSMUST00000121931.1
Clk2




CDC-like kinase 2




chr11_-_106159902 0.169 ENSMUST00000064545.4
Limd2
LIM domain containing 2
chr1_+_181150926 0.159 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr16_-_90284300 0.158 ENSMUST00000163419.1
Scaf4
SR-related CTD-associated factor 4
chr5_-_31291026 0.157 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr17_-_79355082 0.157 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr16_+_20516962 0.155 ENSMUST00000003318.5
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr18_+_56707725 0.152 ENSMUST00000025486.8
Lmnb1
lamin B1
chrX_-_145505175 0.150 ENSMUST00000143610.1
Amot
angiomotin
chr4_-_91399984 0.149 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr16_-_90284412 0.138 ENSMUST00000039280.7
Scaf4
SR-related CTD-associated factor 4
chr16_-_84835484 0.117 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr18_+_37300799 0.109 ENSMUST00000051754.1
Pcdhb3
protocadherin beta 3
chr11_+_70432627 0.107 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
Arrb2






arrestin, beta 2






chr15_-_76656905 0.106 ENSMUST00000176274.1
Cyhr1
cysteine and histidine rich 1
chr12_-_79296266 0.104 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chr2_-_165898951 0.101 ENSMUST00000136842.1
Zmynd8
zinc finger, MYND-type containing 8
chr17_+_12119274 0.099 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr11_-_114066174 0.080 ENSMUST00000041627.7
Sdk2
sidekick homolog 2 (chicken)
chr5_-_24445166 0.078 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr18_+_82554463 0.073 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr12_-_112674193 0.073 ENSMUST00000001780.3
Akt1
thymoma viral proto-oncogene 1
chr11_+_22512088 0.073 ENSMUST00000059319.7
Tmem17
transmembrane protein 17
chr1_+_135729147 0.071 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr5_-_24445254 0.071 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr17_+_37193889 0.070 ENSMUST00000038844.6
Ubd
ubiquitin D
chr5_-_138155694 0.066 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr12_+_24831583 0.061 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr4_+_129513581 0.059 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr2_-_168206875 0.058 ENSMUST00000057793.4
Adnp
activity-dependent neuroprotective protein
chr12_-_112673944 0.056 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1
chr11_-_86807624 0.051 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr3_-_95133989 0.046 ENSMUST00000172572.2
ENSMUST00000173462.2
Scnm1

sodium channel modifier 1

chr2_-_180776900 0.043 ENSMUST00000108878.1
Bhlhe23
basic helix-loop-helix family, member e23
chr12_+_21111778 0.042 ENSMUST00000050990.9
Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr5_-_134456702 0.041 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr2_-_180776749 0.039 ENSMUST00000061098.2
Bhlhe23
basic helix-loop-helix family, member e23
chr16_+_84835070 0.038 ENSMUST00000009120.7
Gabpa
GA repeat binding protein, alpha
chr3_-_75956888 0.034 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr3_+_135826075 0.029 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr6_+_17065129 0.023 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr1_-_153487639 0.023 ENSMUST00000042141.5
Dhx9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr11_-_49187159 0.022 ENSMUST00000046522.6
Btnl9
butyrophilin-like 9
chr9_-_111057235 0.018 ENSMUST00000111888.1
Ccrl2
chemokine (C-C motif) receptor-like 2
chr18_-_36766198 0.017 ENSMUST00000061522.7
Dnd1
dead end homolog 1 (zebrafish)
chr12_+_19606929 0.014 ENSMUST00000105167.1
Gm9257
predicted gene 9257
chr13_-_97747373 0.007 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr5_-_114380505 0.003 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr6_-_47594967 0.002 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2


enhancer of zeste homolog 2 (Drosophila)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0015671 oxygen transport(GO:0015671)
0.4 1.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.2 0.7 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 2.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 1.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.2 GO:0001705 ectoderm formation(GO:0001705)
0.1 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.0 0.8 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.6 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392) follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 3.1 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.2 GO:0008623 CHRAC(GO:0008623)
0.2 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 1.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.6 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.