Motif ID: Nr6a1
Z-value: 0.667

Transcription factors associated with Nr6a1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr6a1 | ENSMUSG00000063972.7 | Nr6a1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr6a1 | mm10_v2_chr2_-_38926217_38926454 | -0.31 | 2.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:0060166 | olfactory pit development(GO:0060166) |
0.5 | 1.8 | GO:0046073 | dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073) |
0.3 | 2.2 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.3 | 0.8 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.2 | 0.9 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.2 | 0.7 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.2 | 0.7 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.2 | 0.8 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.1 | 0.7 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.7 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
0.1 | 1.1 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
0.1 | 0.4 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
0.1 | 1.1 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.1 | 0.8 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.1 | 0.3 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
0.1 | 0.8 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.1 | 0.2 | GO:0009838 | abscission(GO:0009838) |
0.1 | 0.4 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.1 | 1.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 0.2 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.0 | 0.2 | GO:0035087 | siRNA loading onto RISC involved in RNA interference(GO:0035087) |
0.0 | 0.6 | GO:0044065 | regulation of respiratory system process(GO:0044065) |
0.0 | 0.5 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
0.0 | 0.4 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.0 | 0.1 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.0 | 1.1 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 1.3 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 1.1 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.8 | GO:0030317 | sperm motility(GO:0030317) |
0.0 | 0.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 0.6 | GO:0003341 | cilium movement(GO:0003341) |
0.0 | 1.2 | GO:0051225 | spindle assembly(GO:0051225) |
0.0 | 0.7 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.9 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.1 | 0.7 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 0.9 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 1.1 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.1 | 0.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 0.7 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 2.2 | GO:0001741 | XY body(GO:0001741) |
0.1 | 0.5 | GO:0033391 | eukaryotic translation initiation factor 4F complex(GO:0016281) chromatoid body(GO:0033391) |
0.1 | 1.1 | GO:0044453 | nuclear membrane part(GO:0044453) |
0.1 | 0.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
0.0 | 0.3 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.4 | GO:0000812 | Swr1 complex(GO:0000812) |
0.0 | 0.8 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 0.7 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 1.5 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905) |
0.4 | 1.4 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.3 | 0.9 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
0.3 | 2.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.3 | 0.8 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.3 | 0.8 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.2 | 0.7 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.1 | 0.7 | GO:0043532 | angiostatin binding(GO:0043532) |
0.1 | 0.4 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 1.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.1 | 0.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.1 | 0.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.1 | 1.1 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.4 | GO:0071253 | connexin binding(GO:0071253) |
0.0 | 0.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.6 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 1.5 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 1.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 1.3 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.2 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.0 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 2.2 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.4 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 1.6 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.8 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 0.4 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 1.0 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.7 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 1.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.8 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.1 | 1.3 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.0 | 0.7 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.0 | 0.9 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 2.4 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.6 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.0 | 0.5 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 1.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.4 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.0 | 1.4 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |